CN107242870A - The conduction of velocity assay method of nerve fibre - Google Patents
The conduction of velocity assay method of nerve fibre Download PDFInfo
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- CN107242870A CN107242870A CN201710433445.2A CN201710433445A CN107242870A CN 107242870 A CN107242870 A CN 107242870A CN 201710433445 A CN201710433445 A CN 201710433445A CN 107242870 A CN107242870 A CN 107242870A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/389—Electromyography [EMG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
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Abstract
The invention discloses a kind of conduction of velocity assay method of nerve fibre, including S1, the wrist of electro photoluminescence normal human, obtain the muscle movement oscillogram A at palm and mark t1、t3And P1；S2, electro photoluminescence ancon, obtain oscillogram B and mark t2；If t=t2‑t1；S3, stimulator A stimulate stimulator B after wrist, delay t to stimulate ancon, obtain muscle movement oscillogram and mark P2；S4, Fiber number of the calculating conduction of velocity less than (L/t) and total nerve fibre ratio are P2/P1；S5, judge whether P2=P1, if into S7, otherwise into S6；S6, t=t+ Δ t, perform S3；S7, drawn according to conduction of velocity (L/t) and the ratio normal human nerve fibre conduction of velocity distribution map.The distribution of the conduction of velocity of speed nerve fibre can be measured, this is conducive to the disease damage situation of subsequent analysis patients' neural's fiber.
Description
Technical field
The present invention relates to the technical field that electromyogram evoked potentuial measuring system detects MNCV, more particularly to a kind of nerve
The conduction of velocity assay method of fiber.
Background technology
Nerve fibre can be divided into A classes, B classes, C class three major types, and wherein A classes nerve fibre is the myelinated fibre of somatic nerves, B classes
Nerve fibre is that autonomic nerve has marrow preganglionic fiber, and C class nerve fibres are the unmyelinated nerve fibers of somatic nerves or autonomic nerve.A classes god
Conduction of velocity through fiber is most fast, can reach 12-120m/s.The bigger nerve fibre of diameter, conduction of velocity is faster, and electromyogram exists
In clinical examination, the conduction velocity in nerve fiber surveyed is typically only capable to be measured to the speed of most fast big nerve fibre, it is impossible to anti-
Reflect the impaired situation of overall nerve fibre.
Such as diabetic, it will usually occur peripheral nerve fibrosis, and lesion is often opened from small nervous fibres
Begin, that is, the conduction of velocity of small nervous fibres can be involved first, and big nerve fibre is then slowly involved again, if
With traditional movement conduction determination techniques, the speed for measuring most fast nerve fibre that can only be single, as a result without representativeness.
For example, the measure of existing MNCV is to provide human nerve certain electricity by electromyogram instrument to pierce
Swash, reach after certain intensity and time threshold, cause the excitement of nerve fibre, and arrive neuromuscular juinction along the trend of nerve
Target muscles, muscle can be converted to the action potential of a muscle, instrument record to action electricity after the excitement of nerve is received
Behind position, after the time of the distance specifically conducted divided by conduction, the speed of nerve fibers conduct can be detected.Such as Fig. 1 and 2
It is shown.
The content of the invention
There is provided a kind of survey of the conduction of velocity of new nerve fibre for the problem of present invention exists for prior art and deficiency
Determine method.
The present invention is to solve above-mentioned technical problem by following technical proposals：
The present invention provides a kind of conduction of velocity assay method of nerve fibre, and its feature is that it comprises the following steps：
S1, the wrist using stimulator A electro photoluminescence normal humans, the muscle that electromyogram evoked potentuial measuring system obtains at palm are moved
Make potential waveform figure A and electro photoluminescence to the period obtained before muscle action potential oscillogram A is designated as t1, electro photoluminescence is to obtaining
Obtaining the period after muscle action potential oscillogram A is designated as t3, and muscle action potential oscillogram A crest value is P1；
S2, the ancon using stimulator B electro photoluminescence normal humans, the electromyogram evoked potentuial measuring system obtain the muscle at palm
Electro photoluminescence to the period for obtaining muscle action potential oscillogram B is simultaneously designated as t by action potential waveform figure B2；
If t initial value=t2-t1；
Stimulator B stimulates the ancon after S3, the stimulator A electro photoluminescence wrist, delay time t, and the electromyogram induces
Potentiometer obtains the muscle action potential oscillogram of the palm, in the muscle action potential oscillogram as caused by stimulator B
The crest value of contraction of muscle waveform is designated as P2；
S4, the quantity for calculating nerve fibre of the conduction of velocity less than (L/t) and nerve fibre sum ratio are P2/P1,
Wherein, L is distance of the ancon to the wrist；
S5, judge whether P2=P1, if then entering step S7, otherwise into step S6；
S6, t=t+ Δ t, and step S3 is repeated, Δ t is constant；
S7, drawn according to conduction of velocity (L/t) and the ratio normal human nerve fibre conduction of velocity distribution map.
It is preferred that further comprising the steps of：
The conduction of velocity distribution map of the nerve fibre of patient is drawn according to step S1-S7；
Relatively and analyze patient nerve fibre conduction of velocity distribution map and normal human nerve fibre conduction speed
Spend distribution map.
On the basis of common sense in the field is met, above-mentioned each optimum condition can be combined, and produce each preferable reality of the present invention
Example.
The positive effect of the present invention is：
The present invention provides a kind of conduction of velocity assay method of nerve fibre, can measure the conduction of speed nerve fibre
The distribution of speed, this is conducive to the disease damage situation of subsequent analysis patients' neural's fiber.
Brief description of the drawings
Fig. 1 is the detection figure of the speed of the nerve fibers conduct of prior art.
Fig. 2 is muscle action potential oscillogram of the nerve fibre of prior art after electro photoluminescence.
Fig. 3 is the flow chart of the conduction of velocity assay method of the nerve fibre of present pre-ferred embodiments.
Fig. 4 is the structural representation of the conduction of velocity assay method of the nerve fibre of present pre-ferred embodiments.
Fig. 5 stimulates corresponding muscle action potential oscillogram for the wrist of present pre-ferred embodiments.
Fig. 6 stimulates corresponding muscle action potential oscillogram for the ancon of present pre-ferred embodiments.
Fig. 7 stimulates corresponding muscle action potential oscillogram for the wrist and ancon of present pre-ferred embodiments.
Embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention
In accompanying drawing, the technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is
A part of embodiment of the present invention, rather than whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art
The every other embodiment obtained on the premise of creative work is not made, belongs to the scope of protection of the invention.
The present embodiment provides a kind of conduction of velocity assay method of nerve fibre, can measure the biography of speed nerve fibre
Lead the distribution of speed.
As shown in figure 3, the conduction of velocity assay method of the nerve fibre comprises the following steps：
Step 101, the wrist (see Fig. 4) that stimulator A is placed on to normal human, the wrist of electro photoluminescence normal human, hand
Corresponding muscle action potential occurs for the short abductor muscle of thumb of the palm, and electromyogram evoked potentuial measuring system obtains wrist and stimulated at corresponding palm
Muscle action potential oscillogram A, as shown in figure 5, electro photoluminescence to the period obtained before muscle action potential oscillogram A is remembered
For t1, electro photoluminescence to the period obtained after muscle action potential oscillogram A is designated as t3, and muscle action potential oscillogram A
Crest value be P1.
Step 102, the ancon (see Fig. 4) that stimulator B is placed on to normal human, the ancon of electro photoluminescence normal human should
Electromyogram evoked potentuial measuring system obtains the muscle action potential oscillogram B at palm, as shown in fig. 6, by electro photoluminescence to obtaining the flesh
Meat action potential waveform figure B period is designated as t2.T in Fig. 6 waveform2It is significantly greater than the t in Fig. 21, because neural
The excited transmission distance of fiber is from ancon to palm, to be increased much to palm distance compared to wrist.
After the stimulator A electro photoluminescence wrist, delay time t, the stimulator B electro photoluminescence ancon works as t<t2-t1When,
After wrist is stimulated, the neuromuscular juinction of nerve fibre is two-way, is transferred to palm toward distal end, short abductor muscle of thumb can be caused to shrink, past
Near-end transmission can pass through ancon, when be delayed time t after, stimulator B carry out electro photoluminescence, the neuromuscular juinction of the nerve fibre of ancon
It is also two-way, the transmission of the past distal end of ancon can liquidate and be completely counterbalanced by with the transmission of the past near-end of wrist, formed by
Waveform is identical with the waveform in Fig. 5.
After the stimulator A electro photoluminescence wrist, delay time t, the stimulator B electro photoluminescence ancon, as P2=P1,
After wrist is stimulated, the neuromuscular juinction of nerve fibre is two-way, is transferred to palm toward distal end, short abductor muscle of thumb can be caused to shrink, past
Near-end transmission can pass through ancon, when be delayed time t after, stimulator B carry out electro photoluminescence, the neuromuscular juinction of the nerve fibre of ancon
It is also two-way, ancon is toward during distal end transmission (being transmitted from wrist to palm), and now the transmission of the past near-end of wrist is complete
It is passed on entirely, then the transmission of the past near-end of the transmission of the past distal end of ancon and wrist is not offset completely, the waveform formed by
The waveform gone out for the addition of waveforms in Fig. 5 and 6.
Thus, if t initial value=t2-t1。
Stimulator B stimulates the ancon after step 103, the stimulator A electro photoluminescence wrist, delay time t, now ancon
Transmitting portions of the meeting with wrist proximally of transmitting toward distal end liquidate and offset, after having some nervous excitations to be cancelled, ancon
Stimulation caused by short abductor muscle of thumb shrink wave amplitude can reduce, as shown in fig. 7, the contraction of muscle as caused by stimulator B in Fig. 7
Waveform (second less waveform) crest value is P2.
Step 104, the quantity for calculating nerve fibre of the conduction of velocity less than (L/t) and the total ratio of nerve fibre are
P2/P1, wherein, L is distance of the ancon to the wrist.
By that analogy, auto-programming is set by instrument internal, the delay time t between A, B stimulator in t2-t1In≤t
Travel through until P2=P1, it is possible to draw the conduction of velocity distribution map of all nerve fibres of normal human, this is favourable
In the disease damage situation of later observation person under inspection's nerve fibre.Specifically：
Step 105, judge whether P2=P1, if then entering step 107, otherwise into step 106；
Step 106, t=t+ Δ t, and step S3 is repeated, Δ t is constant；
Step 107, the conduction of velocity distribution according to conduction of velocity (L/t) and the nerve fibre of ratio drafting normal human
Figure.
Then, the conduction of velocity distribution map of the nerve fibre of patient is drawn according to step 101-107, relatively and patient is analyzed
Nerve fibre conduction of velocity distribution map and normal human nerve fibre conduction of velocity distribution map, so as to analyze patient
Nerve fibre disease damage situation.
Although the foregoing describing the embodiment of the present invention, it will be appreciated by those of skill in the art that these
It is merely illustrative of, protection scope of the present invention is defined by the appended claims.Those skilled in the art is not carrying on the back
On the premise of principle and essence from the present invention, various changes or modifications can be made to these embodiments, but these are changed
Protection scope of the present invention is each fallen within modification.
Claims (2)
1. the conduction of velocity assay method of a kind of nerve fibre, it is characterised in that it comprises the following steps：
S1, the wrist using stimulator A electro photoluminescence normal humans, electromyogram evoked potentuial measuring system obtain the muscle movement electricity at palm
Electro photoluminescence to the period obtained before muscle action potential oscillogram A is simultaneously designated as t by digit wave form figure A1, electro photoluminescence is to being somebody's turn to do
Period after muscle action potential oscillogram A is designated as t3, and muscle action potential oscillogram A crest value is P1；
S2, the ancon using stimulator B electro photoluminescence normal humans, the electromyogram evoked potentuial measuring system obtain the muscle movement at palm
Electro photoluminescence to the period for obtaining muscle action potential oscillogram B is simultaneously designated as t by potential waveform figure B2；
If t initial value=t2-t1；
Stimulator B stimulates the ancon after S3, the stimulator A electro photoluminescence wrist, delay time t, the electromyogram Evoked ptential
Instrument obtains the muscle action potential oscillogram of the palm, the muscle as caused by stimulator B in the muscle action potential oscillogram
The crest value for shrinking waveform is designated as P2；
S4, the quantity for calculating nerve fibre of the conduction of velocity less than (L/t) and nerve fibre sum ratio are P2/P1, wherein,
L is distance of the ancon to the wrist；
S5, judge whether P2=P1, if then entering step S7, otherwise into step S6；
S6, t=t+ Δ t, and step S3 is repeated, Δ t is constant；
S7, drawn according to conduction of velocity (L/t) and the ratio normal human nerve fibre conduction of velocity distribution map.
2. the conduction of velocity assay method of nerve fibre as claimed in claim 1, it is characterised in that further comprising the steps of：
The conduction of velocity distribution map of the nerve fibre of patient is drawn according to step S1-S7；
Relatively and analyze patient nerve fibre conduction of velocity distribution map and normal human nerve fibre conduction of velocity point
Butut.
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| CN201710433445.2A CN107242870A (en) | 2017-06-09 | 2017-06-09 | The conduction of velocity assay method of nerve fibre |
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| CN201710433445.2A CN107242870A (en) | 2017-06-09 | 2017-06-09 | The conduction of velocity assay method of nerve fibre |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6132387A (en) * | 1997-07-01 | 2000-10-17 | Neurometrix, Inc. | Neuromuscular electrode |
| US20070149892A1 (en) * | 2005-12-22 | 2007-06-28 | Neurotron Medical Inc. | Apparatus for neuromuscular function signal acquisition |
| US8568312B2 (en) * | 2010-03-12 | 2013-10-29 | MaryRose Cusimano Reaston | Electro diagnostic functional assessment unit (EFA-3) |
| KR20140102879A (en) * | 2013-02-15 | 2014-08-25 | 한국과학기술원 | Electro-acupuncture system |
| CN204336914U (en) * | 2014-12-19 | 2015-05-20 | 李跃群 | Infant nerve conduction velocity monitor |
| CN106473737A (en) * | 2016-11-24 | 2017-03-08 | 张珊珊 | A kind of measuring system based on the sEMG muscle and deep signal of telecommunication |
-
2017
- 2017-06-09 CN CN201710433445.2A patent/CN107242870A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6132387A (en) * | 1997-07-01 | 2000-10-17 | Neurometrix, Inc. | Neuromuscular electrode |
| US20070149892A1 (en) * | 2005-12-22 | 2007-06-28 | Neurotron Medical Inc. | Apparatus for neuromuscular function signal acquisition |
| US8568312B2 (en) * | 2010-03-12 | 2013-10-29 | MaryRose Cusimano Reaston | Electro diagnostic functional assessment unit (EFA-3) |
| KR20140102879A (en) * | 2013-02-15 | 2014-08-25 | 한국과학기술원 | Electro-acupuncture system |
| CN204336914U (en) * | 2014-12-19 | 2015-05-20 | 李跃群 | Infant nerve conduction velocity monitor |
| CN106473737A (en) * | 2016-11-24 | 2017-03-08 | 张珊珊 | A kind of measuring system based on the sEMG muscle and deep signal of telecommunication |
Non-Patent Citations (2)
| Title |
|---|
| 栾松等: "糖尿病周围神经病运动神经传导速度分布", 《中华神经科杂志》 * |
| 赵定麟主编: "《现代脊柱外科学》", 31 January 2017, 上海世界图书出版公司 * |
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