CN106983499A - Optical profile type blood pressure detector and its operating method - Google Patents
Optical profile type blood pressure detector and its operating method Download PDFInfo
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- CN106983499A CN106983499A CN201610040519.1A CN201610040519A CN106983499A CN 106983499 A CN106983499 A CN 106983499A CN 201610040519 A CN201610040519 A CN 201610040519A CN 106983499 A CN106983499 A CN 106983499A
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- blood pressure
- value
- pressure detector
- processing unit
- pulse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02141—Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/0816—Measuring devices for examining respiratory frequency
Abstract
A kind of blood pressure detecting method, is comprised the steps of：Using Photosensing Units body of light product variable signal is obtained from skin surface；Pressure value is calculated during each relative described pulse of time difference in during a pulse of model and body of light product variable signal is estimated according at least one blood pressure between two characteristic points；Calculate the respiratory cycle；Multiple pressure values in the average respiratory cycle are to produce mean blood pressure value；And the mean blood pressure value is shown with display device.
Description
Technical field
The relevant a kind of blood pressure detector of the present invention, particularly about a kind of optical profile type blood that variable signal is accumulated based on body of light
Press detection means and its operating method.
Background technology
When known blood pressure measuring is taken blood pressure, when costing the long period and repeated measurement is generally required compared with confidence values can be obtained.
Furthermore it is known that sphygmomanometer be only capable of carry out passive measurement, and can not continuation active measurement.It is thus known that the survey of sphygmomanometer
Value is only the pressure value of particular condition (such as after user's mood and action tranquil a period of time), and can not reflect institute really
There are situation, such as pressure value when sleeping.
In view of this, it is necessary to propose a kind of blood pressure detector for enough continuing to monitor pressure value.
The content of the invention
The present invention provides one kind, and using body of light product variable signal, (Photoplethysmography, PPG call PPG letters in the following text
Number) obtain the pressure value of user and the optical profile type blood pressure detector and its operating method of respiratory rate.
The present invention provides optical profile type blood pressure detector and its operation of a kind of average multiple pressure values of utilization respiratory cycle
Method, in the hope of relatively stable mean blood pressure value.
The present invention provides a kind of blood pressure detector, includes light source, Photosensing Units and processing unit.The light source is used to
Illumination skin surface makes light through the tissue of the skin surtace.The Photosensing Units detects the human body group
The emergent light knitted accumulates variable signal to produce body of light.The processing unit is used to estimate model and described according at least one blood pressure
Time difference in during the pulse of body of light product variable signal between two characteristic points with respect to pulse each described during calculate to
A few pressure value, calculates multiple pressure values in respiratory cycle, and the average respiratory cycle to produce mean blood pressure value；Its
In, described at least one blood pressure estimation model includes the time difference between two characteristic points described in during with the pulse
For the multinomial of variable.
The present invention also provides a kind of blood pressure detector, includes light source, Photosensing Units, internal memory and processing unit.It is described
Light source is to illuminate the tissue that skin surface makes light pass through the skin surtace.The Photosensing Units detects institute
The emergent light of tissue is stated to produce body of light product variable signal.The internal memory to store at least one correcting value, wherein, institute
It is estimated blood pressure value and the difference of the measurement pressure value of sphygmomanometer to state correcting value.The processing unit is used to according at least one blood
Time difference in during the pulse of pressure estimation model and body of light product variable signal between two characteristic points is with respect to each institute
Pressure value is calculated during stating pulse, calculates multiple pressure values in respiratory cycle, the average respiratory cycle to produce average blood
Pressure value, and the mean blood pressure value is corrected with the correcting value；Wherein, at least one blood pressure estimation model is included with described
The time difference described in during pulse between two characteristic points is the multinomial of variable.
The present invention also provides a kind of operating method of blood pressure detector, comprises the steps of：Using Photosensing Units from
Skin surface obtains body of light product variable signal；Estimate that model and body of light product become according at least one blood pressure using processing unit
Time difference in during changing the pulse of signal between two characteristic points with respect to pulse each described during calculate pressure value, its
In, described at least one blood pressure estimation model includes the time difference between two characteristic points described in during with the pulse
For the multinomial of variable；The respiratory cycle is calculated using the processing unit；And utilize the average breathing of the processing unit
Multiple pressure values in cycle are to produce mean blood pressure value.
In order to which the above and other objects, features and advantages of the present invention can be become apparent from, it will hereafter coordinate appended diagram, in detail
Carefully it is described as follows.In addition, in the explanation of the present invention, identical components are represented with identical symbol, are first stated clearly herein.
Brief description of the drawings
The body of light that Fig. 1 is detected by the blood pressure detector of the embodiment of the present invention accumulates the schematic diagram of variable signal；
Fig. 2 is the schematic diagram for the pressure value tried to achieve according to the estimation model of the embodiment of the present invention；
Fig. 3 A-3B are the use state of the blood pressure detector of the embodiment of the present invention；
Fig. 4 is the block schematic diagram of the blood pressure detector of the embodiment of the present invention；
Fig. 5 is the schematic diagram of the mean blood pressure value according to the embodiment of the present invention；
Fig. 6 is the flow chart of the operating method of the blood pressure detector of the embodiment of the present invention.
Description of reference numerals
11 body of light accumulate variable signal
21 systolic pressure signals
22 diastolic pressure signals
300 blood pressure detectors
301 light sources
302 Photosensing Units
303 processing units
304 coffrets
305 display devices
306 vibrating elements
307 loudspeakers
308 indicating lights
501 estimated systolic blood pressures
502 estimation diastolic pressures
S skin surfaces
THS、THDBlood pressure thresholds
The Pb respiratory cycles
During Pt pulses
PS1~PS4、PS1'~PS4' characteristic point.
Embodiment
Body of light is accumulated variable signal (PPG) signal and is made up of two parts, during heart contraction, pressure in system vascular,
Volume of blood flow etc., can produce continuity change, and when diastole, aforementioned pressure is relative to be lowered, now a preceding heart
The blood got during contraction, can circulate the phenomenon hit cardiac valves and produce reflexed.
Therefore a complete PPG waveform contains the comprehensive effect that heart contraction is acted on vascular wall pressure itself, profit
Photographically detect the Volume Changes of blood vessel, foregoing PPG signals can be obtained.
In order to obtain the breath signal and blood pressure signal of user from PPG signals, PPG signals are necessarily obtained first, are connect
(such as Fig. 1 Pt) calculates pressure value respectively during each pulse that the relatively described PPG signals of model are estimated using blood pressure, and
Respiratory rate is calculated according to the change of multiple pressure values.
As it was previously stated, a complete PPG waveform contains the comprehensive effect that heart contraction is acted on vascular wall pressure itself
Should.The present invention detects the Volume Changes of blood vessel using optical mode, can obtain foregoing PPG signals.
From the foregoing it will be appreciated that frequency when PPG signals can represent cardiac cycle, but because PPG measures the body of light product of blood vessel
Change, and the blood vessel of Whole Body is connected to each other, therefore by parsing PPG signals, on signal that can be analytically, closed
In blood pressure and the relevant information of respiratory cycle.
For example upon inhalation, muscular exertion, and then further extruding is produced to blood vessel, this can cause PPG signals overall
Up gradually step up and change the shape of PPG signals；Conversely, upon exhalation, loosening all muscles can then make it that PPG signals are integrally past
Under gradually reduce and change the shape of PPG signals.Therefore, by parsing the characteristic point of PPG signals, it can identify user's
Pressure value and respiratory rate (respirationrate).
Moreover, by the Comparison of Gardening Activities with user, blood pressure detecting system output indication can be made, user is used to refer to
Blood pressure and breath state.When such as causing blood pressure to raise because of nervous as user, can by by with detection
The equipment that PPG signals are linked, point out user should loosen, or user caused in Changes in weather blood pressure raise or
When person reduces, user can be pointed out to change clothing amount.The earphone that can be worn by user, with the sense of hearing of voice or music
Prompting mode will be prompted to inform user, or the device carried with by user, and display visual cues are to user, Huo Zhetong
Cross body surface perceptive mode and be prompted to user, for example, vibrate.In addition, also can in sleep when continue recording blood pressure change, with as
The data of long-term health monitoring.
Below in relation to the embodiment that blood pressure and respiratory cycle Pb how are obtained by PPG signals.
First, PPG signals are obtained by blood pressure detector, as shown in figure 1, wherein PPG signals 11 include multiple features
Point PS1-PS4、PS1'-PS4'.Then, the time difference between two characteristic points by recognizing the PPG signals 11 and estimation of arranging in pairs or groups
Model (appearance be specified in after), can with respect to each pulse during Pt try to achieve at least one pressure value, as shown in Figure 2.Fig. 2 is shown respectively
So that line segment is connected and continuous blood pressure value signal is presented between pressure value；Wherein, 21 for example represent systolic pressure signals and 22 for example
Represent diastolic pressure signal.
The blood pressure detector of the embodiment of the present invention can also recognize the rising part of the blood pressure value signal 21,22 respectively
And sloping portion.Such as Fig. 2 embodiment, rising part for example represents air-breathing and sloping portion for example represents expiration.At other
Embodiment among because estimation model is different, rising part may also represent expiration and sloping portion represents air-breathing, have no spy
Definite limitation.After aforementioned information is obtained, respiratory rate further can be calculated according to the blood pressure value signal 21,22, and in real time
Export to property the one at least within this blood pressure value signal and respiratory rate.In addition, can by suggestion device according to pressure value and/
Or respiratory rate and the comparative result of at least one threshold value produce prompting for user's reference.
Therefore, by the blood pressure detector of the embodiment of the present invention, user can be allowed further to understand the life of oneself
Reason situation, reaches the effect of self adjustment.
And the present invention can also note down the blood pressure and breath state of user for a long time, user's conduct is given to export statistics
The reference of adjustment, and the statistics is alternatively arranged as the foundation of decision threshold.
It refer to shown in Fig. 3 A-3B, it is the use state of the blood pressure detector 300 of the embodiment of the present invention.The blood
Pressure detection means 300 is by detecting the PPG signals of the tissue of user, to analyze and show the blood pressure value signal of the user
Change with time.Therefore, the blood pressure detector 300 may be disposed at any appropriate location to detect PPG signals, for example, set
The wrist (as shown in Figure 3A) or arm (as shown in Figure 3 B) of the user are placed in, but is not limited to this.In other embodiment,
The blood pressure detector 300 for example can be combined on portable electronic devices or Wearable electronic installation, for example bracelet, arm
The device that ring, finger ring, pin ring, mobile phone, earphone, personal digital assistant etc. can be contacted with least a portion skin surface.This
Outside, the blood pressure detector 300 also can wire or wirelessly couple Medical Devices, home appliance, vehicle, safety system etc..
It is preferred that the equipment that the blood pressure detector 300 is connected has to show the blood pressure detector 300 in real time
The display device of testing result.
It refer to shown in Fig. 4, the block schematic diagram of its blood pressure detector 300 implemented for the present invention.The blood pressure inspection
Survey device 300 and include light source 301, Photosensing Units 302 and processing unit 303.In some embodiments, the blood pressure detecting dress
300 are put also to include to the display device 305 for the testing result for showing the blood pressure detector 300.In some embodiments, institute
State blood pressure detector 300 and also include the coffret 304 for being used to wire or wirelessly couple with outside display device 305,
Shown in real time with testing result to the display device 305 for exporting the blood pressure detector 300.In other words, institute
Stating display device 305 can include or be not included in the blood pressure detector 300, depending on its application.
The display device 305 for example can be liquid crystal display, plasma display panel, organic light emitting diode display, throwing
The equipment that shadow machine etc. can be used to display image, has no specific limitation, as long as the average blood such as Fig. 5 can be shown by display screen
Pressure value 501,502 (after appearance is specified in).
The light source 301 is, for example, light emitting diode or laser diode, and tissue and energy are adapted to penetrate through to send
The enough light absorbed by tissue.For example, a length of 610 nanometers or 910 nanometers of the light wave of the transmitting light of the light source 301, but simultaneously
It is not limited.The light source 301 makes light through the tissue below the skin surface S to illuminate skin surface S.
It is preferred that there is the blood pressure detector 300 transparent surface can be attached at the skin surface S and protect the light source
301, the light source 301 is then arranged on the inside of the transparent area.Transparent surface transparent material such as with plastics or glass
It is made, have no specific limitation.In some embodiments, the transparent surface is, for example, the surface of light guide, and the light guide
Function with guiding light path.
In some embodiments, when the blood pressure detector 300 simultaneously to detect blood oxygen concentration when, the blood pressure detecting
Device 300 can include the light two light sources to send different wave length respectively；Wherein, the method for detection blood oxygen concentration for example can refer to
The co-owned U.S. Patent Application No. of applicant in this case 13/614,999, the disclosure of which is incorporated by ginseng herein
Examine.
The Photosensing Units 302 is, for example, optical diode (photodiode) or image sensing arrays (image
Sensor array), such as CMOS sensor array (CMOS sensor array), to detect from institute
The emergent light of tissue injection is stated to produce light Volume Changes (PPG) signal, as shown in Figure 1.Using optical diode detection simultaneously
The mode of output PPG signals has been, it is known that therefore being repeated no more in this.The invention reside according to the PPG signal identification blood detected
Pressure value and respiratory rate.The mode for detecting three-dimensional physiological characteristic distribution using image sensing arrays for example can refer to applicant in this case institute
Jointly owned U.S. Patent Application No. 14/955,463, the disclosure of which is incorporated to as reference herein.Described image sense
PPG signals can be exported respectively by surveying each pixel of array, or described image senses the intensity sum of all pixels of array
PPG signals can be used as.Similarly, the Photosensing Units 302 is arranged on the inside of the transparent area.
The processing unit 303 is, for example, microcontroller (MCU), central processing unit (CPU) or application-specific IC
(ASIC), light source 301 described in its electric property coupling and the light sensing unit 302, to control the light source 301 and the light sensation
Survey the corresponding operation of unit 302.The processing unit 303 is used to estimate that model and body of light product become according at least one blood pressure
Pt calculates pressure value, meter during time difference relatively each pulse during changing the pulse of signal 11 in Pt between two characteristic points
Multiple pressure values in the respiratory cycle Pb and average respiratory cycle Pb are calculated to produce mean blood pressure value.In the present embodiment,
The relative value for person's actual blood pressure that the mean blood pressure value is, for example, relative usage, user can be known from according to the mean blood pressure value
The blood pressure of body.
In the present embodiment, during at least one blood pressure estimation model is included with pulse in Pt between two characteristic points
Time difference is the multinomial of variable；Wherein, the multinomial can be an order polynomial, quadratic polynomial or high-order moment, its
Curve for example during fitting the pulse using fitting process (fitting method) described in Pt between two characteristic points and obtain.
The blood pressure estimation model can be for example realized to be built into the processing unit 303 with software and/or hardware.
For example, in Fig. 1, Pt includes multiple characteristic point P during pulseS1-PS4, described two characteristic points are body of light product
Peak P during the pulse of variable signal 11 in PtS2, secondary high level PS4, minimum PS1And secondary low value PS3In wherein two
It is individual.In addition, at least one blood pressure estimation model estimates model and diastolic pressure (DBP) estimation model comprising systolic pressure (SBP).
Fitting process is for example fitted the characteristic point PS1With the characteristic point PS2Between curve, the characteristic point PS2With it is described
Characteristic point PS3Between curve, the characteristic point PS3With the characteristic point PS4Between curve, the characteristic point PS2With the characteristic point
PS1' between curve or the characteristic point PS2With the characteristic point PS4Between curve and obtain, have no specific limitation.
For example, a kind of systolic pressure estimation model can be according to the characteristic point PS2With the characteristic point PS1' (it is next
Pt minimum during pulse) between curve obtained by equation；Wherein, the characteristic point PS2With the characteristic point PS1' when
Between difference for example represented with DT
SBP=-0.095 × DT+188.581 (1)
A kind of diastolic pressure estimation model can be according to the characteristic point PS2With the characteristic point PS4Between curve obtained by equation
Formula；Wherein, the characteristic point PS2With the characteristic point PS4Time difference for example represented with T1.To clearly show that, T1 shows in Fig. 1
It is shown as characteristic point PS2' and characteristic point PS4' time difference.
DBP=-0.344 × T1+174.308 (2)
Foregoing diastolic pressure and the model of systolic pressure are for example, PPG measured values can be corresponded into blood pressure values roughly.
, can be with other mathematical modelings come correspondence, such as comprising more multivariable or more differences if trying to achieve more accurate model
Many powers multinomial of time difference, is not the limitation of the present invention.
Such as SBP and DBP can be write as ∑ akXk(K powers)+C, wherein XkThe time difference is represented, C represents known constant.
A systolic pressure estimation model and a diastolic pressure estimation model are can obtain between any two characteristic points, is only that
It reflects that the degree of blood pressure is different.In the present embodiment, systolic pressure estimation model and diastolic pressure estimation model preferably in
The Share Model (common model) tried to achieve before dispatching from the factory via the PPG signals for counting many people is simultaneously stored in the processing unit
In 303 non-voltile memory.It should be noted that, the characteristic point is not limited to the characteristic point that the present invention is enumerated, its example
Also can according to the single orders of the PPG signals, second-order differential curve extreme value relatively as described in the positions of PPG signals determine.This
Outside, feature point number used in determining the blood pressure estimation model is also not limited to two.
The processing unit 303 for example can try to achieve systolic pressure respectively according to Pt during each relative pulse of equation (1),
To form the systolic pressure signal 21 such as Fig. 2；Wherein, the every bit in the systolic pressure signal 21 represents required by equation (1)
The systolic blood pressure value obtained, and be connected with each other with line segment.The processing unit 303 for example can be according to the relatively each arteries and veins of equation (2)
The diastolic pressure that the period Pt that fights is tried to achieve respectively, to form the diastolic pressure signal 22 such as Fig. 2；Wherein, in the diastolic pressure signal 22
Every bit represents the diastolic blood pressure values tried to achieve by equation (2), and is connected with each other with line segment.
In the present embodiment, the processing unit 303 can also be according to the systolic pressure signal 21 and/or the diastolic pressure signal
22 calculate respiratory cycle Pb.In one embodiment, the processing unit 303 can be using fast fourier algorithm (FFT) according to described
Multiple pressure values of systolic pressure signal 21 and/or the diastolic pressure signal 22 calculate the respiratory cycle Pb.In another embodiment,
The processing unit 303 can utilize two-phase in multiple pressure values of the systolic pressure signal 21 and/or the diastolic pressure signal 22
Time difference between adjacent minimal blood pressure value calculates the respiratory cycle Pb.In other words, the systolic pressure signal 21 and/or it is described relax
The respiratory cycle Pb can be used as by opening the cycle of pressure signal 22.
As can be seen from Figure 2, the systolic pressure signal 21 and diastolic pressure signal 22 calculated by the processing unit 303 are with person user
Breathing and change, and unstable situation is presented.Therefore, the processing unit 303 can be also calculated in the respiratory cycle Pb
Multiple pressure values average value (such as root mean square, but not limited to this), to obtain mean blood pressure value as shown in Figure 5；Wherein,
501 represent estimated systolic blood pressure, and 502 represent estimation diastolic pressure.Fig. 5 shows the embodiment that the respiratory cycle Pb is 6 seconds, according to not
With shape situation, the length of the respiratory cycle Pb can be differed.From Fig. 5 it can be seen that, Fig. 5 mean blood pressure value is than Fig. 2's
Pressure value substantially stablizes many.
Referring again to shown in Fig. 5, it is also shown with multiple measurement pressure values measured by sphygmomanometer.As it was previously stated, this
Person measured by the blood pressure detector 300 of inventive embodiments can be described as relative pressure value.In some embodiments, in the internal memory
At least one correcting value is also stored, wherein, the correcting value is the difference of the measurement pressure value of estimated blood pressure value and sphygmomanometer.
Therefore, then can be by the estimation blood after processing unit 303 obtains estimated blood pressure value (i.e. mean blood pressure value 501,502)
Pressure value plus or minus the correcting value obtain more accurate or personalized pressure value to be corrected；That is, the school
Positive quantity can be measured and stored respectively according to each user, to obtain individualized correcting value.
The coffret 304 is for example wirelessly or by hard wire exported in the mean blood pressure value and respiratory rate at least within
One, such as with the data of the one at least within the default frequency transmission mean blood pressure value and respiratory rate to display device
305 displays in real time；Wherein, wirelessly or non-wirelessly transmission technology has been, it is known that therefore being repeated no more in this.The respiratory rate can be according to institute
State respiratory cycle Pb to be tried to achieve, such as described respiratory cycle Pb inverse is multiplied by 60 seconds.It will be appreciated that when blood pressure inspection
Device 300 is surveyed while when including the display device 305, the coffret 304 can not be implemented, or the coffret
304 are arranged inside the blood pressure detector 300 and between the processing unit 303 and the display device 305.
The display device 305 to show in real time the mean blood pressure value versus time curve (such as Fig. 5's
Estimated blood pressure value 501,502) and/or the respiratory rate numerical value.In addition, the processing unit 303 is also read from the internal memory
The pressure value related at least one blood pressure thresholds THs, THD, and the multiple numerical value is connect directly or by the transmission
Mouth 304 is sent to the display device 305 and shown.For example be shown on the display screen of the display device 305 with lines,
Blood pressure thresholds THs, TH described in numeral or graphicDAnd the numerical value of the respiratory rate, to allow user can be simply from described aobvious
Show that equipment 305 observes itself blood pressure and breathing state.
From unlike known blood pressure detector, blood pressure detector 300 of the invention can show user's in real time
Blood pressure and breathing state.Stated differently, since the blood pressure detector 300 analyzes what the Photosensing Units 302 was detected
PPG signals, therefore when the processing unit 303 receives the PPG signals, you can proceed by and analyze and export the blood
Pressure value signal 21,22 and/or respiratory rate to the display device 305 are shown.Because the processing unit 303 is according to breathing
The cycle average blood pressure value signal 21,22, therefore the display device 305 can start display after a respiratory cycle Pb
Blood pressure.In general, under normal work and rest, the respiratory cycle Pb is about 5-6 seconds.It will be appreciated that different users' meeting
There are different respiratory cycle Pb, different situations also have different respiratory cycle Pb.In other embodiment, when the processing unit 303
When not calculating mean blood pressure value, the display device 305 can show the blood pressure value signal 21,22 such as Fig. 2 in real time.
In addition, in order to lift user's experience, the blood pressure detector 300 can also include suggestion device 305, to root
Cue is sent according to the mean blood pressure value and/or the respiratory cycle and the comparative result of at least one threshold value；Wherein, institute
It is, for example, vibration signal, optical signal, voice signal and/or picture signal to state cue, but is not limited thereto, as long as can
Point out user.
The blood pressure detector 300 of the embodiment of the present invention can be applied to mood and work and rest adjustment.
For example, when the mean blood pressure value of user is not up to or more than blood pressure thresholds THS、THDWhen, the suggestion device 305 is then
Send the cue.Thereby, user can be adjusted by mood, take medicine, adjust clothing amount etc. to cause mean blood pressure value
Recover to normal condition.
For example, when the respiratory rate of user is not up to or during more than threshold value, the suggestion device 305 then sends the prompting
Signal.The respiratory rate is for example shown on display screen simultaneously with frequency values and the estimated blood pressure value 501,502.Such as preceding institute
State, the processing unit 303 is that can calculate the respiratory rate according to a respiratory cycle Pb, and need not be accumulative one minute
Count value.
Depending on the display mode of the cue is according to different application.
For example, the display device 305 is used as the suggestion device simultaneously.When mean blood pressure value and/or respiratory rate do not reach
Arrive or during more than threshold value, the processing unit 303 makes the display device 305 show the prompting by picture signal, for example
Prompting is represented with word, figure, brightness etc..
For example, the blood pressure detector 300 can also be used as the suggestion device comprising vibrating elements 306.When average blood
Pressure value and/or respiratory rate are not up to or during more than threshold value, and the processing unit 303 makes the vibrating elements by vibration signal
306 occur alerting by vibration user.
For example, the blood pressure detector 300 can also be used as the suggestion device comprising loudspeaker 307.Work as mean blood pressure
Value and/or respiratory rate are not up to or during more than threshold value, and the processing unit 303 sends out the loudspeaker 307 by voice signal
Go out sound to remind user.
For example, the blood pressure detector 300 can also be used as the suggestion device comprising indicating light 308.When average blood
Pressure value and/or respiratory rate are not up to or during more than threshold value, and the processing unit 303 makes the indicating light 308 by optical signal
Light to remind user.
In some embodiments, the processing unit 303 is for example (such as real with software and/or hardware with learning algorithm
It is existing), above-mentioned each threshold value can be determined according to the historical record of user, such as blood pressure thresholds, respiratory rate threshold value, but not as
Limit.Such as the multiple threshold value can be classified as sleep during, work during, motion during.The multiple historical record is related
Data be for example stored in non-volatile internal memory.
It refer to shown in Fig. 6, it is the flow chart of the operating method of the blood pressure detector of the embodiment of the present invention, comprising under
Row step：Using Photosensing Units body of light product variable signal (step S61) is obtained from skin surface；Using processing unit according to extremely
Time difference in during the pulse of few blood pressure estimation model and body of light product variable signal between two characteristic points is relative
Pressure value (step S62) is calculated during each described pulse；The respiratory cycle (step S63) is calculated using the processing unit；
And using multiple pressure values in the processing unit average respiratory cycle to produce mean blood pressure value (step S64).
Step S61：Preferably relatively described skin surface S is fixes to the blood pressure detector 300 when operation, to avoid
The PPG signals that the Photosensing Units 302 is sensed are by the influence of noise produced by moving.In addition, the processing unit 303 is also
There can be the algorithm for eliminating mobile produced noise in PPG signals, wherein, the method for eliminating mobile noise for example can refer to this case
The co-owned U.S. Patent Application No. of applicant 13/614,999, the disclosure of which is incorporated by reference herein.
Step S62：The processing unit 303 is opened after the PPG signals from the Photosensing Units 302 are received
Characteristic point (P as shown in Figure 1 during the pulse of the beginning identification body of light product variable signal in PtS1-PS4), it is for example with soft
Part and/or hardware are realized.At least one blood pressure estimation model is prestored in internal memory；Wherein, at least one blood pressure estimation model bag
Containing the multinomial using the time difference between two characteristic points in Pt during the pulse as variable, such as equation (1) and (2).
The processing unit 303 is then by measured the multiple characteristic point PS1-PS4Between time difference (such as ST, DT, T1) bring into
Pt calculates pressure value during at least one described blood pressure estimates model with each relative described pulse, as shown in Figure 2.
Step S63-S64：The processing unit 303 is calculated after multiple pressure values, then breathing week can be directly calculated in time domain
Phase Pb (as shown in Figure 2), or in frequency-domain calculations go out the respiratory cycle Pb using FFT.In the present embodiment,
The respiratory cycle Pb can be used to calculating respiratory rate and be shown for the display device 305, and can be used to averagely described processing
Multiple pressure values that unit 303 is calculated are in the hope of estimated blood pressure value 501,502, as shown in Figure 5.
Then, the respiratory rate and/or the estimated blood pressure value 501,502 are transferred into display device 305 and shown.
In addition, the processing unit 303 also may compare the respiratory rate and/or the estimated blood pressure value 501,502 and at least one threshold
Value sends cue according to this to confirm whether its numerical value is in normal range (NR).
In some embodiments, estimated blood pressure value and sphygmomanometer can be stored in individualized pressure value, internal memory in order to try to achieve
The difference of pressure value is measured to be used as correcting value；Wherein, the correcting value is for example stored in calibration phase by application software, example
Stored as user can input the difference between estimated blood pressure value in Fig. 5 and measurement pressure value to user interface.Formal
During operation, the processing unit 303 is then automatic to correct the estimated blood pressure value 501,502 with the correcting value.
It should be noted that, the display device 305 can show the estimated blood pressure value 501,502 and respiratory rate, but not
Show the measurement pressure value.In some embodiments, the display device 305 may also display Fig. 2 systolic pressure signal 21 and/or
Diastolic pressure signal 22, depending on its application.
It should be noted that, although illustrated in above-described embodiment by taking reflective optic blood pressure detector as an example, but
It is not limited to the present invention.In other embodiment, the blood pressure detector is alternatively penetration Optical devices, wherein only
The set location of light source and Photosensing Units is not quite similar, and its sensing principle is then identical, therefore is repeated no more in this.
It should be noted that, though said in above-described embodiment so that the internal memory is located in the processing unit 303 as an example
It is bright, but the present invention is not limited thereto.In other embodiment, the internal memory can be located at outside the processing unit 303, as long as institute
State processing unit 303 and the internal memory can be read, have no specific limitation.
In addition, in some embodiments, when the processing unit 303 judges change (such as standard of tried to achieve pressure value
Deviation) when exceeding preset range, then stop calculating mean blood pressure value or stop the tried to achieve estimated blood pressure value of output, until required
The pressure value obtained recovers untill preset range.
In summary, it is known that blood pressure detector simultaneously can not show the pressure value of user in real time and can not carry out continuing for a long time
Monitoring, therefore with using upper limitation.Therefore, the present invention also provides a kind of blood pressure detector (such as Fig. 4) and its operating method
(such as Fig. 6), the pressure value and breathing state of user can be calculated and be shown in real time for it.In addition, the blood pressure detector of the present invention
And user can be allowed to adjust the body reason situation of itself by prompting mechanism, effectively to lift user's experience and application.
Although the present invention is disclosed by previous embodiment, it is not limited to the present invention, any institute of the present invention
Belong to the technical staff in technical field with usual knowledge, it is without departing from the spirit and scope of the present invention, various when that can make
Change and modification.Therefore protection scope of the present invention is worked as and is defined depending on the scope that appended claims are defined.
Claims (20)
1. a kind of blood pressure detector, the blood pressure detector is included：
Light source, to illuminate the tissue that skin surface makes light pass through the skin surtace；
Photosensing Units, detects the emergent light of the tissue to produce body of light product variable signal；And
Processing unit, is used to
In being estimated according at least one blood pressure during the pulse of model and body of light product variable signal between two characteristic points
Time difference with respect to pulse each described during calculate at least one pressure value, wherein at least one described blood pressure estimate model bag
Containing the multinomial using the time difference between two characteristic points described in during the pulse as variable,
The respiratory cycle is calculated, and
Multiple pressure values in the average respiratory cycle are to produce mean blood pressure value.
2. blood pressure detector according to claim 1, wherein, described two characteristic points are that the body of light accumulates variable signal
The pulse during in peak, secondary high level, minimum and secondary low value in two of which.
3. blood pressure detector according to claim 1, wherein, the processing unit using fast fourier algorithm according to
Multiple pressure values calculate the respiratory cycle.
4. blood pressure detector according to claim 1, wherein, the processing unit utilizes two phases in multiple pressure values
Time difference between adjacent minimal blood pressure value calculates the respiratory cycle.
5. blood pressure detector according to claim 1, wherein, at least one blood pressure estimation model includes systolic pressure
Estimate model and diastolic pressure estimation model.
6. blood pressure detector according to claim 1, the blood pressure detecting model is also included shows the average blood in real time
The display device of one at least within pressure value and respiratory rate, wherein, the respiratory rate is tried to achieve according to the respiratory cycle.
7. blood pressure detector according to claim 1, the blood pressure detector also includes Tip element, to according to institute
State mean blood pressure value and/or the respiratory cycle produces cue.
8. blood pressure detector according to claim 1, wherein, the Photosensing Units is optical diode or image sensing
Array.
9. blood pressure detector according to claim 1, wherein, the blood pressure detector is incorporated into portable electronic dress
Put or Wearable electronic installation.
10. a kind of blood pressure detector, the blood pressure detector is included：
Light source, to illuminate the tissue that skin surface makes light pass through the skin surtace；
Photosensing Units, detects the emergent light of the tissue to produce body of light product variable signal；
Internal memory, to store at least one correcting value, wherein, the correcting value is the measurement blood pressure of estimated blood pressure value and sphygmomanometer
The difference of value；And
Processing unit, is used to
In being estimated according at least one blood pressure during the pulse of model and body of light product variable signal between two characteristic points
Time difference with respect to pulse each described during calculate pressure value, wherein at least one described blood pressure estimation model include with described
The time difference described in during pulse between two characteristic points is the multinomial of variable,
Calculate the respiratory cycle,
Multiple pressure values in the average respiratory cycle to produce mean blood pressure value, and
The mean blood pressure value is corrected with the correcting value.
11. blood pressure detector according to claim 10, wherein, two characteristic point is that the body of light accumulates variable signal
The pulse during in peak, secondary high level, minimum and secondary low value in two of which.
12. blood pressure detector according to claim 10, wherein, the processing unit utilizes fast fourier algorithm root
The respiratory cycle is calculated according to multiple pressure values.
13. blood pressure detector according to claim 10, wherein, the processing unit utilizes in multiple pressure values two
Time difference between adjacent minimal blood pressure value calculates the respiratory cycle.
14. blood pressure detector according to claim 10, wherein, at least one blood pressure estimation model includes contraction
Pressure estimation model and diastolic pressure estimation model.
15. blood pressure detector according to claim 10, the blood pressure detector also includes described average to export
One at least within pressure value and respiratory rate to display device coffret, wherein, the respiratory rate is exhaled according to
The suction cycle is tried to achieve.
16. blood pressure detector according to claim 10, wherein, the Photosensing Units is optical diode or image sense
Survey array.
17. a kind of operating method of blood pressure detector, the blood pressure detector includes Photosensing Units and processing unit, institute
Operating method is stated to include：
Using the Photosensing Units body of light product variable signal is obtained from skin surface；
In being estimated using the processing unit according at least one blood pressure during the pulse of model and body of light product variable signal
Time difference between two characteristic points with respect to pulse each described during calculate pressure value, wherein, at least one described blood pressure
Estimate that model includes the multinomial using the time difference between two characteristic points described in during the pulse as variable；
The respiratory cycle is calculated using the processing unit；And
Using multiple pressure values in the processing unit average respiratory cycle to produce mean blood pressure value.
18. operating method according to claim 17, the operating method is also included：
The mean blood pressure value is corrected with correcting value using the processing unit, wherein, the correcting value be estimated blood pressure value with
The difference of the measurement pressure value of sphygmomanometer.
19. operating method according to claim 17, wherein, described two characteristic points are that the body of light accumulates variable signal
The two of which in peak, secondary high level, minimum and secondary low value in during the pulse.
20. operating method according to claim 17, wherein, at least one blood pressure estimation model is estimated comprising systolic pressure
Count model and diastolic pressure estimation model.
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| CN201610040519.1A CN106983499A (en) | 2016-01-21 | 2016-01-21 | Optical profile type blood pressure detector and its operating method |
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Application publication date: 20170728 |