CN106618801B - A kind of insertion type artificial cardiac valve conveying device with biasing release structure - Google Patents
A kind of insertion type artificial cardiac valve conveying device with biasing release structure Download PDFInfo
- Publication number
- CN106618801B CN106618801B CN201710033797.9A CN201710033797A CN106618801B CN 106618801 B CN106618801 B CN 106618801B CN 201710033797 A CN201710033797 A CN 201710033797A CN 106618801 B CN106618801 B CN 106618801B
- Authority
- CN
- China
- Prior art keywords
- conveying device
- valve
- insertion type
- type artificial
- elastic support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/2439—Expansion controlled by filaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a kind of insertion type artificial cardiac valve conveying device with biasing release structure to include conveying device and care device, described conveying device is by delivery pipe, cavity, elastic support, releasing sleeve forms, valve memory is provided with described cavity, described elastic support is located at the junction of delivery pipe and cavity, described releasing sleeve is located at the junction of delivery pipe and elastic support, described care device nesting axially moves on a conveyor, care device is by haemostatic clamp, liquid guide flow pipe, biasing assembly, medicine ring group into, described haemostatic clamp is connected with locking silk, described liquid guide flow pipe and hemostasis clipper joint, described medicine ring is connected with heart valve bracket.The apparatus structure of the present invention is simple, easy to use, and release success rate is high, is conveyed suitable for the insertion type artificial cardiac valve of number of ways.
Description
Technical field
The present invention relates to a kind of substitute of tissue and its implanted device, and in particular to one kind has biasing release knot
The insertion type artificial cardiac valve conveying device of structure.
Background technology
Heart is the most important organ of human body, and heart is divided into left and right two parts, and each section includes atrium and ventricle again.It is left
Atrium dextrum and left and right ventricles are separated by atrial septum and interventricular septum respectively.Four cardiac valves, i.e. tricuspid valve, lung in heart be present
Arterial valve, bicuspid valve and aorta petal.In blood circulation of human body system, four cardiac valves play vital effect.
The anoxic blood of systemic circulatory system enters atrium dextrum through vena cave, then enters right ventricle by tricuspid valve, right ventricle shrinks will
Blood is pressed into systemic pulmonary circulation by pulmonary valve, and the blood after lung oxygen saturation returns to atrium sinistrum through pulmonary vein, then through two
Cusp reaches left ventricle, and blood is discharged into sustainer to return to systemic circulatory system by left ventricular contraction by aorta petal.Sustainer
There is left and right coronary ostium under valve.Valve-open when four valvular structures ensure that blood clockwise direction, reverse direction
When close, it is therefore prevented that heart burden caused by blood reflux.But due to a variety of causes, cardiac valves can be caused
Posteriority damage or lesion, such as rheumatism, atherosclerosis etc..In addition, congenital heart disease such as fallot's disease, postoperative
Long term can also produce cusps of pulmonary valve lesion.Valvular function is shown as after valve lesion gradually to lose, as valvular inadequacy is led
Blood reflux is caused, valvular stenosis causes blood circulation not smooth, or incompetence and the two narrow merger, is born so that aggravating heart
Load, causes cardiac failure.It is out chest, heart for the damage of valvular posteriority or lesion, traditional treatment method
After stoping jumping, under Hypothermic Cardiopulmonary Bypass support, open the surgical repair of heart progress diseased valve or manually cardiac valves is put
Change.Existing heart valve prosthesis is divided to two major classes:Metal machinery valve and biovalve.Biovalve is quiet by bovine pericardium, ox neck
It is made after the processing of the animal materials such as arteries and veins valve, porcine aortic valve.
Generally, it is the open openheart surgery carried out under general anesthesia that cardiac valves, which changes operation, in the process the heart
It is dirty stopping and blood flow controlled by cardiopulmonary bypass machine.Traditional open surgery causes significant patient trauma and uncomfortable, and
Expose patients to a variety of potential dangerous, such as infection, apoplexy, kidney failure and for example associated with the use of cardiopulmonary bypass machine
Detrimental effect.
The shortcomings that due to open surgery step, increasingly interested is valvular minimally-invasive and percutaneously puts
Change.By means of being percutaneously compacted to be delivered in conduit, then for example being moved by stock through conduit (or puncture) technology, valve prosthesis
Opening in arteries and veins simultaneously proceeds to heart by descending aorta, and then prosthese is in valve annulus (for example, aortic valvular ring) to be restored
Interior deployment.Although being opened relative to traditional support is conveyed to recover vascular, extensive receiving has been obtained through microcatheter technology,
In the case of entering percutaneous conveying for more complicated prosthetic heart valve, this only has mixing resultant.Prosthetic heart valve
All kinds and construction can be used for percutaneous valve replacement process, and sustained improvement.
The content of the invention
The technical problem to be solved in the present invention is to provide a kind of insertion type artificial cardiac valve with biasing release structure
Conveying device.
To solve the above problems, technical scheme proposed by the present invention is:A kind of insertion type people with biasing release structure
Work cardiac valves conveying device, including conveying device and care device, described conveying device are by delivery pipe, cavity, elasticity
Support, releasing sleeve form, described delivery pipe one end connection handle, other end connection cavity, are provided with described handle
Controller, valve memory is provided with described cavity, described valve memory is connected by seal wire with elastic support, valve
Flexible torque axis is set in film memory, expandable heart valve bracket is provided with described flexible torque axis, it is described
Elastic support be located at the junction of delivery pipe and cavity, elastic support is connected with handle by wire drawing, set on elastic support
There are seal wire gim peg and locking silk gim peg, extend locking silk, described locking silk and shield on described locking silk gim peg
Device connection is managed, described releasing sleeve is located at the junction of delivery pipe and elastic support, and described care device is nested in defeated
Send and axially moved on device, care device is into described stops by haemostatic clamp, liquid guide flow pipe, biasing assembly, medicine ring group
Blood clamps to be connected with locking silk, positioned at the outside of cavity, described liquid guide flow pipe and hemostasis clipper joint, described medicine ring and the heart
Dirty valve bracket connection.
Further, described delivery pipe is by using zirconium dioxide as dispersed phase, using zirconate as presoma, by molten
Tubular structure made of nano composite material prepared by glue-gel method, the mol ratio between the zirconium dioxide and zirconate are
1:(1.2-1.3), manufactured delivery pipe mechanical strength is big, and tearing strength and tensile strength are big, heat endurance and chemical stability
It is good.
Further, described heart valve bracket is radially expandable and compressible support frame, cardiac valves branch
Frame includes flowing into end, outflow end, expansion cell, and described inflow end is connected with medicine ring, and described expansion cell is arranged on stream
Enter between end and outflow end, multiple expansion cells are interconnected with one another the strut member to form network structure, can guarantee that artificial heart
Valve is completely implanted into, and can be combined closely with tissue, improves the success rate of valve implantation.
Further, the both ends of described heart valve bracket are provided with overlay film sewing hole, set overlay film sewing hole energy
The combination degree of tissue and heart valve prosthesis is improved, improves the success rate of valve implantation.
Further, tracer ring is additionally provided with described heart valve bracket, described tracer ring is helical circle, by
No. 45 carbon steel steel wires are made, and set tracer ring effectively to monitor whether heart valve prosthesis is transplanted to correct position on request
Put, while can guarantee that and can be found in time when valve departs from implantation position, take measures in time, prevent valve from blocking vascularization
Thrombus.
Further, by expanding anchor connection, implantation process between described heart valve bracket and flexible torque axis
Middle anchor connection is easily separated from, and is reduced valve release during valve implantation and is lost time, improves the efficiency of transplanting.
Further, the medicine in described medicine ring is anticoagulation medicine, and anticoagulation medicine can guarantee that in artificial heart
The rejection of human body causes blood clotting on heart valve prosthesis when valve implantation is initial, causes the de- of heart valve prosthesis
Fall, while block blood vessel and cause thrombus, improve the transplanting efficiency of heart valve prosthesis.
Further, described biasing assembly sets quantity many between heart valve bracket and flexible torque axis
In 3, set biasing assembly to can guarantee that combining closely between cardiac valves and flexible torque axis, prevent in heart valve xenograft
In cause position deviation, influence transplanting efficiency.
Compared with prior art, beneficial effects of the present invention are embodied in:It is provided by the invention that there is biasing to discharge structure
Insertion type artificial cardiac valve conveying device is implanted into after can artificial valve be compressed by interventional method, artificial after expansion release
The function of valve is identical with happy surgery valve, while is both easy to be loaded into conveying device using elastic support, is easy to again fast
Quick-release is put into target location and combined closely with target location surrounding tissue, when installing conveying, is easy to support tightening up loading
In the conveying device of finite volume, and can struts rapidly after being discharged from conveying device, is easy to be brought into close contact with destination organization,
Sufficient channel of blood flow is formed, while is provided with care device on the apparatus, can guarantee that hemostasis is simultaneously when cardiac valves is implanted into
The blood of outflow is discharged in time, while after the implantation, medicine ring can discharge anticoagulation medicine, mitigate body to artificial heart valve
The rejection of film.The apparatus structure of the present invention is simple, easy to use, and release success rate is high, suitable for the intervention of number of ways
Formula heart valve prosthesis conveying-release strategy, the quick and precisely release of insertion type artificial cardiac valve can be achieved.
Brief description of the drawings
Fig. 1 is the overall structure diagram of conveying device provided by the invention;
Fig. 2 is cavity body structure enlarged drawing;
Fig. 3 is heart valve bracket structure chart;
Wherein:1- conveying devices, 2- care devices, 3- delivery pipes, 4- cavitys, 5- elastic supports, 6- releasing sleeves, 7- hands
Handle, 8- controllers, 9- valve memories, 10- seal wires, 11- flexibility torque axis, 12- heart valve brackets, 13- wire drawings, 14- are led
Silk gim peg (14), 15- locking silk gim pegs, 16- locking silks, 17- haemostatic clamp, 18- liquid guide flow pipes, 19- biasing assemblies,
20- medicine rings, 21- flow into end, 22- outflow ends, 23- expansion cells, 24- overlay film sewing holes, 25- tracer rings.
Embodiment
The invention will be further described with reference to the accompanying drawings and examples, and embodiments of the present invention include but is not limited to
The following example.
As shown in Figures 1 to 3, a kind of insertion type artificial cardiac valve conveying device with biasing release structure, including it is defeated
Device 1 and care device 2 are sent, conveying device 1 is made up of delivery pipe 3, cavity 4, elastic support 5, releasing sleeve 6, delivery pipe 3
It is by using zirconium dioxide as dispersed phase, using zirconate as presoma, the nano composite material prepared by sol-gel process is made
Tubular structure, mol ratio between the zirconium dioxide and zirconate is 1:1.2, manufactured delivery pipe mechanical strength is big, tears
Resistance to spalling and tensile strength are big, and heat endurance and chemical stability are good, the one end of delivery pipe 3 connection handle 7, other end connection cavity
4, controller 8 is provided with handle 7, valve memory 9 is provided with cavity 4, and valve memory 9 passes through seal wire 10 and propped up with elasticity
Frame 5 is connected, and flexible torque axis 11 is set in valve memory 9, expandable cardiac valves is provided with flexible torque axis 11
Support 12, heart valve bracket 12 are radially expandable and compressible support frame, and heart valve bracket 12 includes flowing into end
21st, outflow end 22, expansion cell 23, flow into end and be connected with medicine ring 20, expansion cell 23, which is arranged on, flows into end 21 and outflow end
Between 22, multiple expansion cells 23 are interconnected with one another the strut member to form network structure, can guarantee that heart valve prosthesis is complete
Implantation, and can be combined closely with tissue, the success rate of valve implantation is improved, the both ends of heart valve bracket 12 are provided with
Overlay film sewing hole 24, set overlay film sewing hole to improve the combination degree of tissue and heart valve prosthesis, improve valve and move
The success rate of plant, tracer ring 25 is additionally provided with heart valve bracket 12, tracer ring 25 is helical circle, by No. 45 carbon steel steel wires
It is made, sets tracer ring effectively to monitor whether heart valve prosthesis is transplanted to correct position on request, can guarantee that simultaneously
It can in time find when valve departs from implantation position, take measures in time, prevent valve from blocking vascularization thrombus, cardiac valves
By expanding anchor connection between support 12 and flexible torque axis 11, in implantation process anchor connection be easily separated from, reduce valve
Valve release is lost time in film migration process, improves the efficiency of transplanting, elastic support 5 is located at the company of delivery pipe 3 and cavity 4
Place is met, elastic support 5 is connected by wire drawing 13 with handle 7, and seal wire gim peg 14 is provided with elastic support 5 and locking silk is fixed
Bolt 15, lock and extend locking silk 16 on silk gim peg 15, locking silk 16 is connected with care device 2, and releasing sleeve 6 is positioned at conveying
The junction of pipe 3 and elastic support 5, care device 2 are nested in conveying device 1 and axially moved, and care device 2 is by stopping blooding
Pincers 17, liquid guide flow pipe 18, biasing assembly 19, medicine ring 20 are formed, and haemostatic clamp 17 is connected with locking silk 16, positioned at cavity 4
Outside, liquid guide flow pipe 18 are connected with haemostatic clamp 17, biasing assembly 19 be located at heart valve bracket 12 and flexible torque axis 11 it
Between, set quantity to be no less than 3, set biasing assembly to can guarantee that combining closely between cardiac valves and flexible torque axis, prevent
Position deviation is only caused in heart valve xenograft, influences the efficiency of transplanting, medicine ring 20 is connected with heart valve bracket 12, medicine
Medicine in thing ring 20 is anticoagulation medicine, and anticoagulation medicine can guarantee that the rejection of the human body when heart valve prosthesis transplanting is initial
Reaction causes blood clotting on heart valve prosthesis, causes coming off for heart valve prosthesis, while blocks blood vessel and cause thrombus,
Improve the transplanting efficiency of heart valve prosthesis.
Finally it should be noted that:The above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations;Although
The present invention is described in detail with reference to the foregoing embodiments, it will be understood by those within the art that:It still may be used
To be modified to the technical scheme described in previous embodiment, or equivalent substitution is carried out to which part technical characteristic;And
These modifications are replaced, and the essence of appropriate technical solution is departed from the spirit and model of technical scheme of the embodiment of the present invention
Enclose.
Claims (7)
1. a kind of insertion type artificial cardiac valve conveying device with biasing release structure, it is characterised in that filled including conveying
(1) and care device (2) are put, described conveying device (1) is by delivery pipe (3), cavity (4), elastic support (5) and release set
Cylinder (6) composition, described delivery pipe (3) one end connection handle (7), other end connection cavity (4), described handle are set on (7)
Controller (8) is equipped with, valve memory (9) is provided with described cavity (4), described valve memory (9) passes through seal wire
(10) it is connected with elastic support (5), flexible torque axis (11), described flexible torque axis is set in valve memory (9)
(11) expandable heart valve bracket (12) is provided with, described elastic support (5) is located at delivery pipe (3) and cavity (4)
Junction, elastic support (5) is connected by wire drawing (13) with handle (7), and elastic support is provided with seal wire gim peg on (5)
(14) and silk gim peg (15) is locked, extends locking silk (16), described locking silk on described locking silk gim peg (15)
(16) it is connected with care device (2), described releasing sleeve (6) is located at the junction of delivery pipe (3) and elastic support (5), institute
The care device (2) stated is nested in conveying device (1) and axially moved, and care device (2) is led by haemostatic clamp (17), liquid
Flow tube (18), biasing assembly (19), medicine ring (20) composition, described haemostatic clamp (17) is connected with locking silk (16), positioned at chamber
The outside of body (4), described liquid guide flow pipe (18) are connected with haemostatic clamp (17), described medicine ring (20) and cardiac valves branch
Frame (12) connects.
2. a kind of insertion type artificial cardiac valve conveying device with biasing release structure as claimed in claim 1, it is special
Sign is that described delivery pipe (3) is by using zirconium dioxide as dispersed phase, using zirconate as presoma, passing through sol-gel process
Tubular structure made of the nano composite material of preparation, the mol ratio between the zirconium dioxide and zirconate are 1:(1.2-
1.3)。
3. a kind of insertion type artificial cardiac valve conveying device with biasing release structure as claimed in claim 1, it is special
Sign is, described heart valve bracket (12) is radially expandable and compressible support frame, heart valve bracket (12)
Including flowing into end (21), outflow end (22), expansion cell (23), described inflow end is connected with medicine ring (20), and described is swollen
Swollen unit (23), which is arranged on, to be flowed between end (21) and outflow end (22), and multiple expansion cells (23) are interconnected with one another to form net
The strut member of shape structure.
4. a kind of insertion type artificial cardiac valve conveying device with biasing release structure as claimed in claim 1, it is special
Sign is that the both ends of described heart valve bracket (12) are provided with overlay film sewing hole (24).
5. a kind of insertion type artificial cardiac valve conveying device with biasing release structure as claimed in claim 1, it is special
Sign is, tracer ring (25) is additionally provided with described heart valve bracket (12), and described tracer ring (25) is helical circle,
It is made up of No. 45 carbon steel steel wires.
6. a kind of insertion type artificial cardiac valve conveying device with biasing release structure as claimed in claim 1, it is special
Sign is, by expanding anchor connection between described heart valve bracket (12) and flexible torque axis (11).
7. a kind of insertion type artificial cardiac valve conveying device with biasing release structure as claimed in claim 1, it is special
Sign is that described biasing assembly (19) is located between heart valve bracket (12) and flexible torque axis (11), sets quantity not
Less than 3.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710033797.9A CN106618801B (en) | 2017-01-18 | 2017-01-18 | A kind of insertion type artificial cardiac valve conveying device with biasing release structure |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710033797.9A CN106618801B (en) | 2017-01-18 | 2017-01-18 | A kind of insertion type artificial cardiac valve conveying device with biasing release structure |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106618801A CN106618801A (en) | 2017-05-10 |
CN106618801B true CN106618801B (en) | 2018-03-02 |
Family
ID=58841704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710033797.9A Expired - Fee Related CN106618801B (en) | 2017-01-18 | 2017-01-18 | A kind of insertion type artificial cardiac valve conveying device with biasing release structure |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106618801B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108670498A (en) * | 2018-05-25 | 2018-10-19 | 海口市人民医院(中南大学湘雅医学院附属海口医院) | Intravascular stent and using method thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8216302B2 (en) * | 2005-10-26 | 2012-07-10 | Cardiosolutions, Inc. | Implant delivery and deployment system and method |
AU2011248658B2 (en) * | 2010-04-27 | 2014-09-11 | Medtronic Inc. | Transcatheter prosthetic heart valve delivery device with biased release features |
EP2739247B1 (en) * | 2011-08-05 | 2018-10-10 | California Institute of Technology | Percutaneous heart valve delivery systems |
US9445897B2 (en) * | 2012-05-01 | 2016-09-20 | Direct Flow Medical, Inc. | Prosthetic implant delivery device with introducer catheter |
CN204709078U (en) * | 2015-04-20 | 2015-10-21 | 上海纽脉医疗科技有限公司 | A kind of insertion type artificial cardiac valve induction system |
-
2017
- 2017-01-18 CN CN201710033797.9A patent/CN106618801B/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN106618801A (en) | 2017-05-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11241569B2 (en) | Method and apparatus for long-term assisting a left ventricle to pump blood | |
JP7036556B2 (en) | Stent with valve for replacement of heart mitral and tricuspid valves | |
CN105520792B (en) | A kind of D-shaped insertion type artificial cardiac valve | |
JP2018047242A5 (en) | ||
US8758430B2 (en) | Medical apparatus for the therapeutic treatment of an insufficient cardiac valve | |
CN102458309B (en) | Monoblock type quick-connect prosthetic heart valve and development system and method | |
CN109310497A (en) | For treating the device and its method for implantation of tricuspid regurgitation | |
WO2006026912A1 (en) | An implantable artificial heart valve and implanting and retracting device | |
CN101091675B (en) | Atrioventricular valve bracket of artificial valve of dual discal straps | |
CN109922756A (en) | Valve delivery system | |
CN106794064A (en) | Prothesis implant body conveying device | |
BRPI0822756B1 (en) | HEART VALVE PROSTHESIS SYSTEM AND PROCESS TO PRODUCE HEART VALVE PROSTHESIS. | |
CN104771249B (en) | A kind of insertion type artificial cardiac valve and preparation method thereof | |
JP2013542761A (en) | Intra-annular mounting frame for aortic valve repair | |
CN104068947A (en) | Quick-connect prosthetic heart valve and methods | |
CN104799974A (en) | Involvement type prosthetic heart valve stent with barbs and preparation method thereof | |
CN101045023B (en) | Wire intaking compacting mechanism for self-expanding stent | |
JP2021527545A (en) | Relocation wires and methods for repositioning the prosthetic valve device in the heart chamber, as well as related systems, devices, and methods. | |
CN104758090B (en) | A kind of holder of insertion type artificial cardiac valve and preparation method thereof convenient for being accurately positioned | |
CN106618801B (en) | A kind of insertion type artificial cardiac valve conveying device with biasing release structure | |
JP2023554647A (en) | Venous and arterial compliance restoration | |
CN104758091A (en) | Support for involvement type artificial cardiac valve and preparation method thereof | |
CN204600797U (en) | A kind of supporting structure of the insertion type artificial cardiac valve with agnail | |
Jett et al. | Circulatory support for right ventricular dysfunction | |
CN215130877U (en) | Trunk support assembly capable of shortening cycle time and trunk support implantation system |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180302 Termination date: 20210118 |
|
CF01 | Termination of patent right due to non-payment of annual fee |