CN106596962B - A kind of CODE definite value modification methods based on the attenuation of blood sugar test paper test value - Google Patents
A kind of CODE definite value modification methods based on the attenuation of blood sugar test paper test value Download PDFInfo
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- 238000012360 testing method Methods 0.000 title claims abstract description 156
- 239000008280 blood Substances 0.000 title claims abstract description 106
- 210000004369 blood Anatomy 0.000 title claims abstract description 106
- 238000002715 modification method Methods 0.000 title claims abstract description 8
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 62
- 239000008103 glucose Substances 0.000 claims abstract description 62
- 238000004519 manufacturing process Methods 0.000 claims abstract description 24
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 5
- 238000005516 engineering process Methods 0.000 claims description 11
- 239000002994 raw material Substances 0.000 claims description 8
- 230000007423 decrease Effects 0.000 claims description 4
- 238000000034 method Methods 0.000 abstract description 11
- 239000006227 byproduct Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 description 11
- 239000000126 substance Substances 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 5
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- 238000003487 electrochemical reaction Methods 0.000 description 4
- 238000004587 chromatography analysis Methods 0.000 description 3
- 238000013499 data model Methods 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000013011 mating Effects 0.000 description 3
- 238000003908 quality control method Methods 0.000 description 3
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical compound O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108010015776 Glucose oxidase Proteins 0.000 description 2
- 239000004366 Glucose oxidase Substances 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 229940088598 enzyme Drugs 0.000 description 2
- 229940116332 glucose oxidase Drugs 0.000 description 2
- 235000019420 glucose oxidase Nutrition 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 239000004816 latex Substances 0.000 description 2
- 229920000126 latex Polymers 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000012429 reaction media Substances 0.000 description 2
- 238000012827 research and development Methods 0.000 description 2
- QSHQKIURKJITMZ-OBUPQJQESA-N 5β-cholane Chemical compound C([C@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CCC)[C@@]2(C)CC1 QSHQKIURKJITMZ-OBUPQJQESA-N 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
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- 230000008859 change Effects 0.000 description 1
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- 238000011982 device technology Methods 0.000 description 1
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- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000000835 electrochemical detection Methods 0.000 description 1
- 238000002848 electrochemical method Methods 0.000 description 1
- 230000005518 electrochemistry Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000033116 oxidation-reduction process Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000012123 point-of-care testing Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000012372 quality testing Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 229940075420 xanthine Drugs 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
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Abstract
The present invention relates to a kind of CODE definite value modification methods based on the attenuation of blood sugar test paper test value, it is linear relationship Y=a*X+b according to the test value of blood sugar test paper and blood glucose concentration value, X is blood glucose concentration value, Y is test value, a, b is respectively blood glucose concentration value, the linear relationship parameter of test value, by obtaining a, b numerical value after linear fit, the test value stability fluctuation pattern of blood sugar test paper is：Test value fall is linear relationship p=1 c*t with the time, and p is test value fall, and t is the time, and unit is the moon, and c is parameter, by the numerical value that c is obtained after linear fit；It is by the relationship between this CODE revised blood sugar test value Y and concentration value X, testing time and the date of production interval months t：Y=(a*X+b) * (1 c*t), so the CODE original values of batch blood sugar test paper are (date of production, a, b, c).By this method it is possible to prevente effectively from blood sugar test paper quantitatively detects the shorter practical problem of the term of validity caused by product is fluctuated due to stability, effectively extend the term of validity and test accuracy for expanding basis weight products.
Description
Technical field
The invention belongs to enzymatic-electrochemical reaction technology, microelectrode surface Electroanalytical Chemistry technology, photoelectric type bio-sensings
Device technology and POCT field of fast detection are specifically related to a kind of CODE definite values amendment side to decay based on blood sugar test paper test value
Method.
Background technology
Electroanalytical Chemistry (Electroanalytical Chemistry) is an important branch of Instrumental Analysis, it
It is a kind of analysis method set up based on the electroresponse for measuring a certain chemical system or sample.It is the object of measure
The component part of a chemical cell is formed, by measuring certain physical quantitys of battery, such as current potential, electric current, conductance or electricity,
It acquires the content of substance or measures certain electrochemical properties.
Blood sugar test paper in existing system for detecting blood sugar, basic principle are glucose oxidase electrode methods, it is will to pass
A kind of method that the glucolase chemical detection of system combines with electrochemical detection method.Utilize the product of oxydasis glucose
By being reacted with special reaction medium, in electrode surface the electrochemical reaction of electronics transfer occurs for the oxidisability of hydrogen peroxide.
Due to the gain and loss of electronics, so as to generate electric current on the electrode.Due to the difference of glucose content, the amount of generated hydrogen peroxide
Also different, the electron amount that reaction medium participates in the gain and loss of electrochemical reaction institute in electrode surface is also different, is macroscopically showing as
Generate the of different sizes of electric current.Therefore we can design a kind of reaction system, by the size of detecting electrode kinetic current come
Judge the content of glucose in solutions.Reactive Mechanism of Electrode signal is as shown in Figure 1.
Electrochemical method is potentiostatic method used by detecting electric current, and by applying certain current potential, which should be situated between
Oxidation-reduction potential of the matter in reaction system solution.Kinetic current is larger when initial is then gradually reduced, with the increasing of time
Long, when electrochemistry and chemical reaction reach stable state, electric current is held essentially constant.Control regular hour acquisition current value, the ginseng
Number reflects the content for the glucose for participating in reaction to a certain extent.One can be made according to size of current and the concentration of glucose
Fixed relation curve, otherwise according to the curve, we can obtain the glucose content in solution to be measured.
Based on the system for detecting blood sugar that design, research and development are got up on the basis of enzyme electrode, for detecting in blood sample
Glucose content.Other than glucose, this method can also be used to detect other important biomolecule media, as cholesterol, lactate,
Xanthine, cholane, flesh ammonia enzyme and alcohol etc. have the substance of electro-chemical activity.
Due to blood sugar test paper prepared by production technology horizontal factor, difference batch, in quantitative context of detection, there are certain batches
Between it is poor, so as to cause the deviation of test result, so existing similar product is in terms of production technology on the market, using batch default
Value CODE methods define the quantitative testing result reduction formula of every batch of test paper product.So as to ensure the test knot of every batch of product
The accuracy of fruit.
However, since blood sugar test paper is designed into bioactivity raw material, and it is known that the activity of bioactivity raw material with
Time can gradually decay.So with a batch blood sugar test paper, according to specification require place environment place, test result also with
Time and gradually reduce, when its test result reduce amplitude reache a certain level after, that is, cause its test result deviation excessive from
And test result fails, i.e., the blood sugar test paper for quantitatively detecting is more than the term of validity and fails.Generally refer to according to correlations such as regulations
It leads, test value deviation reaches and is set to failure after 10%, is instructed with this, causes for the effective of the blood sugar test paper that quantitatively detects
Phase is limited and shorter.
Invention content
The purpose of the present invention be based on quantitative testing test paper such as blood sugar test paper stability experiment study, analyze its test value with
Time fluctuation rule, it is proposed that a kind of CODE definite value modification methods based on the attenuation of blood sugar test paper test value；The present invention is based on
A kind of definite value modification method that blood sugar test paper test value is established with time fluctuation rule, on the basis of existing definite value CODE
On, test value stability fluctuation pattern is brought into CODE formulating methods, is worked out by CODE, effectively corrects blood sugar test paper test
As a result, test value is avoided to be influenced with time fluctuation, so as to effectively improve accuracy in detection；Simultaneously because CODE establishments are introduced and are surveyed
Examination value, so as to effectively break through the restriction of test value deviation 10% before amendment, can effectively increase amendment with time fluctuation rule
Preceding test value deviation amplitude, so as to the term of validity for extending quantitative detection product of actual high degree.
The technical scheme is that：
It is a kind of based on blood sugar test paper test value attenuation CODE definite value modification methods, it is characterised in that according to the following steps into
Row：It is linear relationship Y=a*X+b first according to the test value of blood sugar test paper and blood glucose concentration value, therefore derives X=(Y-b)/a,
Wherein X is blood glucose concentration value, and Y is test value, and a, b are respectively blood glucose concentration value, the linear relationship parameter of test value, using blood glucose
Test paper tests the test value of three groups or more known blood glucose concentration values, after linear fit, the numerical value of a, b is obtained, according to stabilization
Journal of Sex Research is made under existing manufacturing condition as a result, under the premise of bioactivity raw material and production technology are not altered
The test value stability fluctuation pattern of standby blood sugar test paper is：Test value fall and time are linear relationship, p=1-c*t,
Wherein p is test value fall, and t is the time, and unit is the moon, and c is test value fall, the parameter of linearly relationship,
After linear fit, the numerical value of c is obtained；By the revised blood sugar test value Y of this CODE and blood glucose concentration value X, survey
Examination time and the date of production interval months t between relationship be：Y=(a*X+b) * (1-c*t), so the CODE of batch blood sugar test paper
Original value is (date of production, a, b, c).
Blood glucose meter can either be manually entered code or the setting inspection of network-side remote input code means by code bar
Blood glucose instrument CODE before survey.Blood glucose meter has self-clocking and date calibration function.Blood sugar test paper in blood glucose meter is based on silk
The enzymatic-electrochemical biosensor that the electrochemical reaction technology of the glucose oxidase catalysis on wire mark brush electrode surface is developed.
It can realize the quick and precisely detection of the glucose content of denier sample.
Blood glucose meter is first set by the modified CODE values of the present invention according to printing above blood sugar test paper outer packing before use
CODE, after modified CODE input blood glucose meter, by machine plug-in, system for detecting blood sugar detection can be converted into automatically
As a result conversion formula, and test value stability fluctuation pattern formula is also introduced simultaneously, so as to which effectively subsequent test be tied
Fruit is converted to the concentration value of instrument report result, and corrects product use time with producing the interval at the time of making the product to test result
Influence, improve the accuracy of testing result.
It is existing that the test value stability fluctuation pattern of blood sugar test paper according to the present invention is not limited to only our company
The data model obtained under manufacturing condition can also be the data model of other type function, these data models
Purpose is in order to preferably be fitted the stability fluctuation of description test value, convenient for Mathematical treatment.
CODE valued methods according to the present invention and its detecting system are applicable in but are not limited to blood sugar test paper, colloidal gold is exempted from
Epidemic disease chromatographic test paper, latex immune chromatography test paper, fluorescence immune chromatography test paper etc. are related to the quantitative inspection of bioactivity raw material stability
Examining system.It is such to be related to the stepping quantitative detection system of detected value caused by bioactivity raw material stability,
To use CODE valued methods of the present invention, accuracy in detection and its term of validity are effectively improved.
The present invention, can using the blood sugar test system of the CODE based on blood sugar test paper test value stability fluctuation pattern definite value
Decline phenomenon effectively to correct the test value occurred during blood sugar test paper use with the time, avoid the decline of test value
The phenomenon that causing test result grade less than normal inaccurate, test accuracy is improved, while extremely significantly extend test paper to make
With the term of validity, significant economic benefit is brought for enterprise's production and user's use.
Description of the drawings
Fig. 1 is the Reactive Mechanism of Electrode schematic diagram of the blood sugar test paper in existing system for detecting blood sugar.
Specific embodiment
A preferred embodiment example according to the present invention, is illustrated, invention by taking blood sugar test paper and blood glucose meter as an example
The immune chromatography test papers quantitative detection systems such as applicable and colloidal gold, latex.
Embodiment 1：By taking blood glucose meter as an example
It is a kind of based on blood sugar test paper test value attenuation CODE definite value modification methods, it is characterised in that according to the following steps into
Row：It is linear relationship Y=a*X+b first according to the test value of blood sugar test paper and blood glucose concentration value, therefore derives X=(Y-b)/a,
Wherein X is blood glucose concentration value, and Y is test value, and a, b are respectively blood glucose concentration value, the linear relationship parameter of test value, using blood glucose
Test paper tests the test value of three groups or more known blood glucose concentration values, after linear fit, obtains the numerical value 200 of a, the numerical value of b
It is 300, therefore Y=200*X+300, according to results of stability, before bioactivity raw material and production technology are not altered
It puts, under existing manufacturing condition, the test value stability fluctuation pattern of prepared blood sugar test paper is：Test value declines
Amplitude is linear relationship with the time, and p=1-c*t, wherein p are test value fall, and t is the time, and unit is the moon, and c is test
It is worth fall, the parameter of linearly relationship, after linear fit, the numerical value for obtaining c is 0.0034；Therefore p=1-
0.0034*t, by the revised blood sugar test value Y of this CODE and between blood glucose concentration value X, testing time and the date of production every other month
Number t between relationship be：Y=(a*X+b) * (1-c*t), so the CODE original values of batch blood sugar test paper for (20160606,200,
300,0.0034).By the CODE tables built in blood glucose meter it is known that (20160606,200,300,0.0034) simplify,
2478. event CODE definite values are 2478.Test is before use, it is 2478 first to manually adjust blood glucose meter CODE, then inside blood glucose meter automatically
Select corresponding parameter (20160606,200,300,0.0034), date when blood glucose meter is then used according to tester, automatically
To t values；Blood glucose meter obtains test value after tester's test, then according to according to revised test value concentration value relationship y=
(200*X+300) * (1-0.0034*t) calculates the blood sugar concentration of test sample automatically, is then reported out institute's test sample
Concentration value and early warning.
Embodiment 2：By taking blood glucose meter as an example
In the case where bioactivity raw material and production technology do not change, according under the existing manufacturing condition of our company
Research and development technology and creation data count blood sugar test paper test value stability fluctuation pattern as p=1-0.0034*t, and wherein p is
Test value fall, t are the time, and unit is the moon；By taking a collection of blood sugar test paper that our company develops in the recent period as an example, finished product production
Date be on 06 07th, 2014, test value linear fit curve be Y=215X+210, linear fit coefficient R2=
0.9968, therefore CODE definite values are corrected used by this batch blood sugar test paper as (20140607,215,210,0.0034), Ran Houtong
The CODE tables built in blood glucose meter are crossed it is known that (20140607,215,210,0.0034) can be reduced to 1328, wherein first
Position 1 represents the date 20140607, and second 3 represents 215, and third position 2 represents 210, and the 4th 8 represents 0.0034；So batch examination
The CODE definite values of paper are 1328.
The blood glucose meter for being built-in with the modified CODE definite values compilation facility of the present invention is taken, this blood glucose meter has clocking capability simultaneously
And date calibration function.The code bar for being built-in with CODE values 1328 is inserted into blood glucose meter read port, blood glucose meter reads CODE values,
Then test paper is inserted into blood glucose meter, the quality-control product that definite value is 5.5mmol/l glucose is taken to test, instrument report result is
5.4mmol/l。
The blood glucose meter of no modified CODE definite values compilation facility of the built-in present invention is taken, according to company's blood glucose meter production note
Record, the CODE for consulting the mating original blood glucose meter of this batch of test paper are 32, i.e., built-in linear fitting formula is Y=215X+210, according to
Quality testing department records, the mating original blood glucose meter of this batch of test paper, and test result preparation meets national standard and company standard during manufacture.But
The test paper term of validity is 2 years, through expired.The Quality Control for being 5.5mmol/l according to specification direct operation test concentration of glucose
As a result liquid is shown as 3.2mmol/l, hence it is evident that and definite value quality-control product concentration deviation is excessive and fails.Therefore after the present invention is used to correct
CODE blood glucose meters, keeping life is obviously prolonged.
The a collection of blood sugar test paper of the production on the 15th of September in 2015 is taken, the CODE of mating original blood glucose meter is 37, according to Ben Faxiu
Positive CODE definite values are 3378, and the control liquid that concentration of glucose is taken to be 11.5mmol/l detects respectively, original blood glucose meter test knot
Fruit is 11.0mmol/l, and deviation takes the blood glucose for the blood glucose meter definite value function of being built-in with modified CODE according to the present invention close to 5%
Instrument is tested, and code CODE is 3378, as a result the control liquid that test concentration of glucose is 11.5mmol/l is shown as 11.3mmol/
L, deviation is significantly less than 5%, therefore test accuracy is obviously improved.
The present invention is using the blood sugar test of the CODE based on blood sugar test paper test value stability fluctuation pattern definite value, Ke Yiyou
Effect corrects the test value occurred during blood sugar test paper use with the time and declines phenomenon, and avoiding the decline of test value causes
The phenomenon that test result grade less than normal is inaccurate effectively realizes accurate and stable quantitative detection.It is extremely significant simultaneously to extend
Test paper is effectively improved the feasibility of manufacturer's yield amplification, band is used for enterprise's production and user using the term of validity
Significant economic benefit is carried out.
It should be noted last that more than specific embodiment is merely illustrative of the technical solution of the present invention and unrestricted,
Although the present invention is described in detail with reference to preferred embodiment, it will be understood by those of ordinary skill in the art that, it can be right
Technical scheme of the present invention is modified or replaced equivalently, equal without departing from the spirit and scope of technical solution of the present invention
It is intended to be within the scope of the claims of the invention.
Claims (1)
1. a kind of CODE definite value modification methods based on the attenuation of blood sugar test paper test value, it is characterised in that carry out according to the following steps：
Linear relationship Y=a*X+b first according to the test value of blood sugar test paper and blood glucose concentration value, thus derive X=（Y-b）/ a, wherein X
For blood glucose concentration value, Y is test value, and a, b are respectively blood glucose concentration value, the linear relationship parameter of test value, using blood sugar test paper
The test value of three groups or more known blood glucose concentration values is tested, after linear fit, the numerical value of a, b is obtained, is ground according to stability
Study carefully as a result, under the premise of bioactivity raw material and production technology are not altered, it is prepared under existing manufacturing condition
The test value stability fluctuation pattern of blood sugar test paper is：Test value fall is linear relationship p=1-c*t, wherein p with the time
For the blood glucose value after decline and the ratio of original test value, c*t is test value fall, and t is the time, and unit is the moon, and c is
The parameter of test value fall, linearly relationship after linear fit, obtains the numerical value of c；It is repaiied by this CODE
Relationship between just preceding blood sugar test value Y and concentration value X, testing time and the date of production interval months t is：Y=(a*X+b)*
(1-c*t), so the CODE original values of batch blood sugar test paper are：The date of production, a, b, c.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201788165U (en) * | 2009-06-19 | 2011-04-06 | 广州达优医疗设备有限公司 | Portable intelligent blood glucose meter |
| CN103901079A (en) * | 2013-12-20 | 2014-07-02 | 杭州世佳电子有限公司 | Test paper with code information and manufacturing method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DK1077636T3 (en) * | 1998-05-13 | 2004-05-24 | Cygnus Therapeutic Systems | Signal processing for measurement of physiological analytes |
| EP1943006A4 (en) * | 2005-10-28 | 2009-11-11 | Prime Solution Inc | Rotary fan press |
| RU2706691C2 (en) * | 2007-12-10 | 2019-11-20 | Асцензия Диабетс Кэар Холдингс АГ | Method of determining analyte concentration |
| WO2009125930A1 (en) * | 2008-04-08 | 2009-10-15 | All Medicus Co.,Ltd. | Bio-sensor |
| US20100166942A1 (en) * | 2008-12-29 | 2010-07-01 | Chia-Nan Wang | Method for Searching Parameter Codes of a Biosensor and Method for Producing a Biosensor Chip Matching a Biosensor |
| US9289168B2 (en) * | 2008-12-29 | 2016-03-22 | Medtronic Minimed, Inc. | System and/or method for glucose sensor calibration |
| US10330629B2 (en) * | 2013-03-14 | 2019-06-25 | Ascensia Diabetes Care Holdings Ag | System error compensation of analyte concentration determinations |
| US9649058B2 (en) * | 2013-12-16 | 2017-05-16 | Medtronic Minimed, Inc. | Methods and systems for improving the reliability of orthogonally redundant sensors |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201788165U (en) * | 2009-06-19 | 2011-04-06 | 广州达优医疗设备有限公司 | Portable intelligent blood glucose meter |
| CN103901079A (en) * | 2013-12-20 | 2014-07-02 | 杭州世佳电子有限公司 | Test paper with code information and manufacturing method thereof |
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