CN1064611A - Intraocular lens with variable optical strength of astigmatism correction ability - Google Patents

Intraocular lens with variable optical strength of astigmatism correction ability Download PDF

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Publication number
CN1064611A
CN1064611A CN 91109670 CN91109670A CN1064611A CN 1064611 A CN1064611 A CN 1064611A CN 91109670 CN91109670 CN 91109670 CN 91109670 A CN91109670 A CN 91109670A CN 1064611 A CN1064611 A CN 1064611A
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lens
lens body
ring
micromotion
periphery
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罗伯特·G·威利
威廉·G·马丁
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ROBERT G WILEY
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ROBERT G WILEY
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Priority claimed from US07/667,671 external-priority patent/US5108429A/en
Priority claimed from US07/669,499 external-priority patent/US5203788A/en
Application filed by ROBERT G WILEY filed Critical ROBERT G WILEY
Publication of CN1064611A publication Critical patent/CN1064611A/en
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Abstract

A kind of adjustable focal length intraocular lens 32 has on lens body 34 and a plurality of predetermined extra power is reacted with the position that changes the lens body in the eyes selectively to carry out the actuation body 38 that focal power and astigmatism are adjusted.After human lens 20 underwent operative were extractd, the intraocular lens who implants ophthalmic was very near the optical signature of natural lens.Crystalline lens implantation person can by the adjustable focal length intraocular lens repeatedly the vision behind the corrective surgery improve or do not need to operate again or use uninterruptable power to reach near perfect vision.Crystalline lens keep stable up to external control signal be applied on the actuation body with proofread and correct by other reason cause depart from the deviation of improving vision the time end.

Description

Intraocular lens with variable optical strength of astigmatism correction ability
The present invention relates to a kind of intraocular lens, be specifically related to a kind of intraocular lens's of change focal power and make it have the device of astigmatism correction ability.
The crystalline lens of human eye is positioned at the center position of pupil back and is subjected to corneal protection.In normal human eye, crystalline lens is limpid and is symmetric basically that its relative nonreentrant surface forms roughly globular intercept.Crystalline lens and cornea are collaborative to be focused light on the retina.Retina then with neural and brain synergism, make the photoinduction that projects on the retina become video.
The refraction that occurs in cornea and crystalline intravital light converts the optical correction that diopter is about 60 degree to, and wherein the diopter of cornea is about 40 degree, and lenticular diopter is about 20 degree.Also have other refraction structure in the eyes, but do not consider for the description of simplifying theme.
Cataract be eyes normally be that limpid crystalline lens becomes opaque a kind of state gradually.This opacification generally will experience one long period, reduces by the growth of lenticular light quantity with opacity.Along with weakening of the transmittancy of cataractous lens, the ability of eye response video is also just along with weakening.Finally may cause losing one's sight.Owing to do not eliminate the known method of the turbidity of cataractous lens, generally must be with the crystalline lens of surgical removal muddiness so that light is not arrived on the retina by pupil by the moon with hindering.Cataractous lens is extractd by the otch that the top in cornea and sclera junction cuts out an approximate horizontal.
In case crystalline lens falls with surgical removal, light just can waltz through pupil and pass on the retina.As mentioned above, eye's lens plays very important aggregation capability.Therefore, behind the lens extraction, the diopter of the visual system of eyes is " lacking " 20 degree approximately, and light no longer can correctly focus on the retina.Glasses, contact lens and intraocular lens can adopt after the cataract surgery to make light focus on three kinds of optical visual aids on the retina again usually.
Glasses comprise with eye's cornea and separate the lens that a distance is provided with.The air gap between lens and the cornea forms one greater than 7% image magnification.Unfortunately, it is the same that brain can not make this amplification become in two eyes, and the result is that echo has appearred in an object.This is a specific question, if a people only has an oriented cataract of eyes.Glasses have in fact also limited peripheral visual acuity.
Contact lens directly is attached on the eye's cornea, thereby has eliminated the air gap.As a result, the image magnification of contact lens is more much smaller than the image magnification of glasses, and brain generally can merge eyes and the image that the eyes of not wearing contact lens are seen that has contact lens by.Yet contact lens is not so perfect.For example, contact lens is quite fragile and be easy to remove from its tram on cornea.In addition, contact lens must regularly replace, because protein accumulation on minute surface, may cause conjunctivitis.And, need do many people among the old people of cataract operation and not have and correctly take or embed the desired hand coordination of contact lens.
Before and after nineteen fifty-five, the intraocular lens can replace the cataractous lens of excision first as optical visual aid.This intraocular lens is planted to be placed in the eyes, thereby can very closely simulate the optical signature by its natural lens that is replaced.Different with glasses, adopt the intraocular lens who correctly makes and place in fact not have deformation of image.Equally, limit with stealth that mirror is different to be, do not have protein accumulation on the intraocular lens and need not patient to take care of.
For the intraocular lens is implanted in the eyes, the surgeon will cut an otch or opening usually so that the intraocular lens is embedded in the eyes on sclera and cornea.Usually, the stable lasso of intraocular lens's adhering member is flexible and can bends Zhe where necessary and come by this opening.The minimal openings length that therefore, must cut out normally by basically rigid, have a lens body of circular periphery or cry the diameter decision of eyeglass usually.Certainly, the opening that cuts out on the eyes is preferably as much as possible little so that the risk of ocular damage reduces to minimum.In several years, some intraocular lenss are with making as the flexible material of silicones, therefore can folding up by less otch and implant in the eyes always in the past.
The practice of transplanting at present the intraocular lens is to use such as by the PMMA(polymethyl methacrylate) the suitable biocompatible material of material make be substituted in surgical operation such as camera oculi anterior crystalline lens or the lenticular intraocular lens of camera oculi posterior the time, such as the normal crystalline human lens of extracing when the cataract surgery.But one of present existing problem of intraocular lens is to determine lenticular focal power before surgical operation.This can be for example by at surgical operation previous crops ultrasonic scanning and measure patient's diopter, then lenticular focal power made correct clinical estimation and realize in the such mode of the correct diopter of determining eyes.Yet, even adopt existing best medical skill and most advanced and sophisticated optical device, the ophthalmologist is also from failing to proofread and correct the regulative mechanism of this focal length variations ability from the distance vision to the near vision, even and do not exist in the intraocular lens system that can regulate the minor variations of spherical focal power or astigmatic focal power after the implantation.Like this, most patient needs distance vision and the near vision of using glasses to obtain accurately to focus on after the crystalline lens implant surgery of routine.
The intraocular lens of prior art generally is not that plano-convex structure is exactly the structure of biconvex, and each curved surfaces forms a spherical intercept.Crystalline lens is put into eyes by same a kerf that the excision cataractous lens cuts out.As mentioned above, this otch generally is to cut out along close cornea in the top of eyes and sclera intersection.Among all postoperative patients, have 1/3rd to have tangible astigmatism approximately, and there have 1/3rd patient to carry out spherical adjusting at the used after operation glasses approximately to be clear in the hope of seeing clearly.In fact in all cases, itself causes astigmatism surgical operation, this astigmatism postoperative several leading week of surgery or even the several months in have significant fluctuation.
The astigmatism that causes after the operation is attributable to adjoin on the eyes healing characteristic of the cutting part that passes through when extracing cataractous lens and embedding the intraocular lens.More particularly, the otch on the eyes often heals very slowly, just healing fully of eight thoughtful years possibly.Between the eyes healing stage, wound location tends to spread apart, and makes before the surgical operation that to be that globular cornea becomes basically non-spherical.Because otch is horizontal alignment haply, this diffusion generally is along vertical meridian of eye.Behind surgical operation, originally cornea is steeper on vertical meridian of eye.Along with the eyes healing, cornea becomes more smooth on vertical meridian of eye.Therefore, originally may be that the optical system of globular eyes becomes the toroid shape always, the vertical meridian of eye of this optical system can provide a kind of optics focal power different with horizontal meridian of eye.This non-spherical configuration of visual system is commonly referred to as " astigmatism ".
This scattered-light number of degrees that of causing change to some extent according to the physical characteristic of type, the quantity that whether has suture or used suture and the type of being sure to mouthful, skill that the surgeon adopted and treatment and eyes.For example, use that thin nylon suture material caused to depart from spheric deviation generally smaller than using silk thread or absorbable suture.Generally speaking, the scattered-light diopter that causes changes in 0.5 to 5 degree scope.Postoperative initial astigmatism is generally caused by the vertical meridian of eye steepening.The astigmatism in later stage then is that the vertical meridian by cornea flattens and causes.The postoperative scattered-light orientation and the number of degrees in most of the cases can not calculate to a nicety.Postoperative astigmatism generally will be with needing the medical glasses of periodic replacement to proofread and correct along with the eyes healing.
In some cases, although the ophthalmologist has done maximum effort, be placed into crystalline lens in the patient's eyes because spherical estimation difference and owing to the astigmatic situation that is changing does not provide good long distance visual acuity with surgical operation.Because surgical operation itself may cause the scattered-light number of degrees that occur after cataract surgery and astigmatism axle that significant the variation taken place, thus the postoperative certain hour of surgery-generally be several weeks or the several months-before can not determine accurate astigmatism degree and astigmatism spool exactly.Owing to can not easily old intraocular lens be won and reach the vision of the new intraocular lens with different focal powers being packed into surgical operation and can suitably endanger patient, so patient must rely on glasses that the true visual acuity that focuses on is provided accurately.In other words, although there is no need to wear the glasses of heavy, the bulky higher number of degrees, patient must put on one's glasses usually and obtain the vision of best focusing again.
Once did repeatedly to attempt to provide a kind of correction in astigmatism of expecting behind the surgical operation to occur or the intraocular lens's that its focal power can change after implantation trial.United States Patent (USP) 4,575,373 disclose the intraocular lens that a kind of available laser is regulated, and this crystalline lens adopts laser to change the intraocular lens's of implantation focal power on the spot.This intraocular lens's outer shroud is to be with color plastic processing manufacturing to make it to absorb the laser energy selectively with a kind of nontoxic hot shortness, thereby makes intraocular lens's shape that irreversible variation take place, and increases its focal power.
United States Patent (USP) 4,816,031 discloses a kind of intraocular lens system, this system comprises second crystalline lens that a slice PMMA crystalline lens implant, softness that is placed on it and shape are easy to adapt to, thereby and is used to adjust the electromechanical circuits that two distances between the crystalline lens are regulated the focus of intraocular lens systems.
United States Patent (USP) 4,601,722 disclose a kind of intraocular lens, this intraocular lens has the lens body and the magnetic devices that are partly formed by a plurality of lens body, and this magnetic devices is used for after each several part embeds by the otch on the eyes separately each several part being assembled into lens body in eyes.
United States Patent (USP) 4,512,039 discloses a kind of postoperative scattered-light intraocular lens that remedies, and this lenticular vertical meridian of eye that places at last optically is weaker than horizontal meridian of eye.Guarantee correct placement by touching the tip along the vertical meridian of eye setting.
The U.S. special 4,298,996 discloses a kind of intraocular lens's of being used for magnetic and has lived system admittedly, and this system has one or more supports that stretch out from lens body.Each support has a pair of magnetic fixed component that is placed on the relative both sides of iris, and the magnetive attraction that runs through iris whereby need not the crystalline lens fix in position suture or cut out otch on iris.
United States Patent (USP) 4,277,852 disclose a kind of intraocular lens who has the astigmatism correction function, and this intraocular lens is with a bearing support or touch pin structure and combine to guarantee the correct optics orientation of implant.
Once did repeatedly to attempt to provide a kind of intraocular lens's of variable optical strength trial, this intraocular lens's focal power changes to proofread and correct according to the power that applies from the crystalline lens outside and expect the astigmatism that occurs behind surgical operation.United States Patent (USP) 4,787,903 disclose a kind of intraocular lens who takes charge of Nei Ershi (prism) lens in the annular expense that includes, and it is to use such as the material with high refractive index of polymethyl methacrylate to make.Cover a kind of composite so that slick outer surface to be provided on department's Nei Ershi element in the expense, this composite can be with suitable material, for example can change its refractive index when being subjected to the excitation of electric energy or radiant energy lattice or liquid crystal material are made.Crystalline lens have one be used for accepting the cooperation lasso or the picking up of other of energy from the electric field that produces to coupling lasso power supply station by external power source can device.The coupling lasso can be contained on the frame, implant or place by wearing lenticular patient or ophthalmologist round eye socket.In this patent application document, mention, some cladding material be can be between two or more states conversion, each state has different refractive indexs; Some other material then can provide the refractive index of continuous variable, and this index may be to stablize constant maybe may be returned to its initial value after energy disappears.But it is that this patent does not indicate these materials for what material.
United States Patent (USP) 4,601,545 disclose a kind of variable optical strength intraocular lens system, and this system comprises a kind of optically active molecule material such as liquid crystal.By an in check stimulus field, such as a voltage matrix by geometrical configuration, be applied on the crystalline lens, just can obtain the refractive index of a variable gradient.The level of a correspondence and vertical conductor matrix apply the electrostatic field that is produced by the applied voltage of controlling selectively at each discrete point, thereby produce the gradient refractive index.
United States Patent (USP) 4,564,267 disclose a kind of pancratic crystalline lens, and this crystalline lens can comprise at least one lenticular compound crystalline lens that is formed by photoelectric crystal and implements electric control by an electric field being applied to one.Photoelectric crystal also places between first and second transparent electrode plates, and each battery lead plate includes a plurality of concentric annular transparent electrodes.Receive power supply on the electrode and can produce and traverse crystalline electric field, this electric field produces the refractive index with lensing and distributes.Electric field can change lenticular focal length according to the current potential of input.
United States Patent (USP) 4,373,218 disclose a kind of intraocular lens of variable optical strength, and this intraocular lens comprises a fluid expansion capsule that is used to hold liquid crystal material, and a liquid crystal material and an electrode and a microprocessor combination are to change lenticular refractive index.An electrode is set in corpus ciliare can implants the intrascleral microprocessor of human eye to offer one with the proportional input signal of desired adjusting with one.This microprocessor produces the current potential that traverses liquid crystal material and controls refractive index, to obtain according to the desired adjusting of the relative position of eye.It can be to form on the electrode of the tectal thin transparent material of one deck on the inside of fluid expansion capsule that the output voltage of this microprocessor is applied to.
In recent years, magnetic resonance imaging (MRI) has been substituted surgery and the radiography method as the observation inside of human body of seeking and visiting.Health stands an effect that makes the atom of health along the high-intensity magnetic field of the southern orientations in north.A frequency modulation does not have the radio signal and is transmitted through health so that molecule produces vibration till their upsets.When radio signal stopped, molecule can back turn over, and made each atom become a small fm radio station, and its signal is detected by a MRI scanning device.
Purpose of the present invention be exactly will by apply an external fields of force that crystalline intravital actuating device is arranged, to change lenticular focal power and astigmatism correction amount in the eyes with the similar identical mode of MRI.
The present invention relates to a kind of intraocular lens with a flexible lens body middle body, this middle body be by a kind of by an outer shroud around the limpid material of optics form, this outer shroud is responsive to external fields of force, such as magnetic force.Utilize external fields of force, can change the shape of outer shroud, make lens body come correction of astigmatism along predetermined axis is elongated.Outer shroud can also be used for changing lenticular focal power by the mode that changes the crystalline lens spheroid form.
In general, the intraocular lens device that is used to implant in the eyes of the present invention comprises: optics limpid, flexible, be circular and have the lens body of a periphery haply; Harder ring with the inner rim on the periphery that is attached to lens body; Be attached to lens body and this encircle both one of on actuating device, with reach the shape that can change lens body selectively with reversing and keep changing after shape with one or more characteristics of regulating lens body, comprise focal power and astigmatism correction, this actuating device reacts to change the shape of lens body to the appearance of external fields of force.
The present invention relates to a kind of crystalline lens of adjustable focal length, this crystalline lens can be made the intraocular lens who implants in the human eye.This lens device comprises a transparent lens body with a periphery; An installing ring that stretches around the periphery of at least a portion of lens body; And a plurality of being connected between this ring and the lens body periphery installed round the micromotion that is equally spaced former (micromo-tor).Each micromotion original device reacts to external control signal and changes position and the diameter and/or the circumference of relevant portion of the periphery of lens body with action selectively, with the change focal power with carry out astigmatism correction.Handling the former power of micromotion can be by external power source input and the internal memory energy supply that deposits in when the implantation lens device for future use.
In one embodiment, but lens device comprises the internal ring of a breathing and harder outer shroud, a micromotion original device is attached on this outer shroud and adjustable ground and interior engagement of loops.This micromotion original device can be made the tuning fork form with the parallel fork thigh of a pair of cardinal principle, and this stretches in the internal ring both sides the fork thigh and is connected on the pedestal that is attached on the outer shroud.Internal ring is formed with pair of flanges, is formed with in order to clamp this groove to flange releasedly on the apparent surface of two fork thighs.The micromotion original device also comprises a linear orientation device that is connected between tuning fork pedestal and the internal ring.The power that drives the micromotion original device can be provided by extra power, and this extra power can be ultrasound wave, static, magnetic field, laser equal energy source.The power of micromotion original device also can be before implanting, for example be stored in as potential energy in the micromotion original device for future use.
In another embodiment, installing ring is formed by a plurality of sections, and the micromotion original device is controlled the lap of sections, is formed with the groove of collaborative work on the apparent surface of lap.Be formed with a hollow marginal portion on the periphery of lens body, lap stretches by this hollow marginal portion.The effect of micromotion original device is the circumference that changes ring, changes the configuration of lens body thus.
In other embodiments, the micromotion original device can comprise nut device or orbital motion device of fluid-operated piston being connected between the inner and outer ring and cylinder apparatus, spiral groove type screw thread and collaborative work.These allow adjoining of two rings produce relative axial and radial motion between the part, thereby change the position or the configuration of the lens body in the eyes.
In an artificial lenticular example application, perfection or approaching perfectly vision can be proofreaied and correct or be adjusted to crystalline lens implantation person's postoperative vision repeatedly.It is stable that focal power after the lenticular change and astigmatism correction can keep, till when implantation person need apply external fields of force proofread and correct the deviation that departs from perfect vision that caused by other factors (changing such as the astigmatism that occurs usually) in agglutination, thereby need not to change glasses and make eyes keep good focusing.In addition, because of the existence of passive constrained system is arranged, crystalline lens of the present invention is stable, can keep focal length and astigmatism correction constant after removing external fields of force.This crystalline lens does not need successive power source, does not need by circuit and electrode matrix power source to be coupled on the crystalline lens material yet, also need not with power coupling lasso to the continuous power of crystalline lens supply.This crystalline lens can be regulated at an easy rate: increases and decreases spherical crystalline lens focal power, perhaps increases and decreases astigmatic crystalline lens focal power, thus can frequently lenticular focal length be finely tuned on demand in life patient.
The invention still further relates to a kind of adjustable focal length crystalline lens, this crystalline lens can be made a kind of intraocular lens who implants in the human eye.This lens device comprise one transparent and flexible and have a lens body of a periphery; Be used for this lens body is installed in the interior device of eyes, such as leg, lasso or ring; The control device in chosen position and orientation, this device is to occur with the form round the micromotion original device that is equally spaced between a plurality of peripheries that are connected lens body and the erecting device, each micromotion original device to a predetermined external energy (for example ultrasound wave) thus react and change focal power and carry out astigmatism adjusting to change the lens body in the eyes or the position of part lens body selectively.
In one embodiment, but erecting device comprises internal ring and a harder outer shroud of the breathing on the periphery that is formed on lens body, and the micromotion original device is connected between outer shroud and the internal ring.In another embodiment, erecting device can be a pair of lasso that is connected to the termination on the periphery of lens body by the micromotion original device that has.In another embodiment again, erecting device then is a pair of hook circle that is connected to the termination on the periphery of lens body by the micromotion original device that has.
The micromotion original device can be a kind of linear orientation device, and it has the pedestal and the tensile bar that is attached on the lens body that are attached on outer shroud, lasso or the hook circle.The power of micromotion original device can be provided by extra power, and this extra power can be ultrasound wave, static, magnetic field, laser equal energy source.In addition, potential energy for example can be stored in outer shroud or the linear orientation device so that after implantation external trigger device is reacted.
In an artificial lenticular example application, crystalline lens implantation person's postoperative vision can proofread and correct repeatedly or be adjusted near ideally tightly burnt vision.It is stable that focal power after the lenticular change and astigmatism correction can keep, till when implantation person need apply external fields of force proofread and correct the deviation that departs from perfect vision that caused by other factors (changing such as the astigmatism that occurs usually) in agglutination, thereby need not to change glasses and make eyes keep good focusing.In addition, because of the existence of passive constrained system is arranged, crystalline lens of the present invention is stable, can keep focal length and astigmatism correction constant after removing external fields of force.This crystalline lens does not need successive power source, does not need by circuit and electrode matrix power source to be coupled on the crystalline lens material yet, also need not with power coupling lasso to the continuous power of crystalline lens supply.This crystalline lens can be regulated at an easy rate: increases and decreases spherical crystalline lens focal power, perhaps increases and decreases astigmatic crystalline lens focal power, thus can frequently lenticular focal length be finely tuned on demand in life patient.
By below in conjunction with the accompanying drawing detailed description of the preferred embodiment, the people who is familiar with this professional technique promptly can be easy to above-mentioned and other advantage of the present invention had clearly and understand, in the accompanying drawings:
Fig. 1 is the side sectional view of normal eye before extracing natural lens;
Fig. 2 is typical prior art intraocular lens's a front view;
Fig. 3 has been a crystalline lens shown in Figure 2 along the commentaries on classics of vertical meridian of eye 3-3 intercepting 90 ° cutaway view;
Fig. 4 is the cutaway view of crystalline lens shown in Figure 2 along horizontal meridian of eye 4-4 intercepting;
Fig. 5 is the side sectional view of human eye shown in Figure 1 after implanting intraocular lens shown in Figure 2;
Fig. 6 is the front view of intraocular lens device of the present invention;
Fig. 7 is the cutaway view of lens device shown in Figure 6 along the intercepting of 7-7 line;
Fig. 8 is the front view of the intraocular lens device of the first substituted type embodiment of the present invention;
Fig. 9 is the cutaway view of lens device shown in Figure 8 along the intercepting of 9-9 line;
Figure 10 is the front view of the intraocular lens device of the second substituted type embodiment of the present invention;
Figure 11 is the cutaway view of lens device shown in Figure 10 along the intercepting of 11-11 line;
Figure 12 is the cutaway view of lens device shown in Figure 10 along the intercepting of 12-12 line, has changeed an angle;
Figure 13 is the front view of the intraocular lens device of the 3rd substituted type embodiment of the present invention;
Figure 14 is the phantom of lens device shown in Figure 13 along the periphery of 14-14 line intercepting;
Figure 15 is the partial enlarged drawing of a part of the ring of lens device shown in Figure 14;
Figure 16 is the amplification partial rear view of the flexible lens body of lens device shown in Figure 14;
Figure 17 is the front view of the intraocular lens device of the 4th substituted type embodiment of the present invention;
Figure 18 is that lens device shown in Figure 7 is set in the partial front elevation view under the focal power enlarging state;
Figure 19 is the partial front elevation view of the intraocular lens device of the 5th substituted type embodiment of the present invention;
Figure 20 is the front view of the intraocular lens device of the 6th substituted type embodiment of the present invention;
Figure 21 is included in the partial enlarged drawing of the shape keeper that can regulate selectively in the lens device shown in Figure 20;
Figure 22 is the phantom that the part of the periphery of lens device shown in Figure 20 intercepts along the 22-22 line;
Figure 23 is the partial front elevation view of the intraocular lens device of the 7th substituted type embodiment of the present invention;
Figure 24 is the schematic block diagram in order to the basic controlling device of handling the actuation body in each crystalline lens assembly of the present invention;
Figure 25 is the front view of the device that uses with control device shown in Figure 24;
Figure 26 is the schematic block diagram in order to the automaton of handling device of the present invention shown in Figure 25 and the actuation body in each crystalline lens assembly;
Figure 27 is the front view of an intraocular lens device of the present invention;
Figure 28 is the amplification view of a part of lens device shown in Figure 27 along the intercepting of 28-28 line;
Figure 29 is the amplification view of a part of lens device shown in Figure 27 along the intercepting of 29-29 line;
Figure 30 is the front view of a substituted type embodiment of intraocular lens device of the present invention;
Figure 31 is the amplification view of a part of lens device shown in Figure 30 along the intercepting of 31-31 line;
Figure 32 is the amplification view of a part of lens device shown in Figure 30 along the intercepting of 32-32 line;
Figure 33 is the amplification view that is used for the second former substituted type embodiment of the micromotion of lens device shown in Figure 28;
Figure 34 is the amplification view that is used for the 3rd former substituted type embodiment of the micromotion of lens device shown in Figure 28;
Figure 35 is the amplification view that is used for the 4th former substituted type embodiment of the micromotion of lens device shown in Figure 28;
Figure 36 is the front view with intraocular lens device of a ring-like attachment arrangement of the present invention;
Figure 37 is the front view of the substituted type embodiment of the intraocular lens device with a pair of ferrule type attachment arrangement of the present invention;
Figure 38 is the amplification view of a part of the second substituted type embodiment of the intraocular lens device with a supporting leg type attachment arrangement of the present invention;
Figure 39 is the amplification view of a part of the 3rd substituted type embodiment of the intraocular lens device with a supporting leg type attachment arrangement of the present invention;
Figure 40 is used to detect and stores be used for selectively intraocular lens device of the present invention being positioned and the block diagram of the system of directed data;
Figure 41 is used for after in intraocular lens device of the present invention is implanted eyes selectively it being positioned and the block diagram of directed system.
Referring to Fig. 1, there is shown a normal eye who marks totally by label 10.Eyes 10 comprise one, and to cover be the cornea 12 of an opening on the spheric sclera 14 basically.Cornea 12 has an iris 16 with a pupil 18 on the opening of inherent sclera 14.The back location of pupil 18 has the light that will enter to focus on crystalline lens 20 on the retina 22 on the eyes inner surface, and this retina is connected to the brain (not shown) by optic nerve 24.Crystalline lens 20 is located on the position that pupil 18 hits exactly later and by cornea 12 and is protected.In normal eyes 10, crystalline lens 20 is limpid and is symmetric basically that it is spherical intercept haply that its relative nonreentrant surface forms.The light that crystalline lens 20 and cornea 22 will shine synergistically focuses on the retina 22.Retina 22 then with optic nerve 24 and brain synergism, the photoinduction that projects on the retina 22 is become video.
The refraction that occurs in the light in cornea 12 and the crystalline lens 20 converts the optical correction that diopter is about 60 degree to, and wherein the diopter of cornea 12 is about 40 degree, and the diopter of crystalline lens 20 is about 20 degree.Also have other refraction structure in the eyes 10, but do not consider in order to simplify description at this.
Cataract be eyes 10 normally be that limpid crystalline lens 20 becomes opaque a kind of state gradually.This opacification generally will experience one long period, and the light quantity by crystalline lens 20 reduces with the growth of opacity.Along with the transmittancy of cataractous lens 20 weakens, the ability of eyes 10 induction videos is also just along with weakening.Finally may cause losing one's sight.Owing to do not eliminate the known method of the turbidity of cataractous lens 20, generally must be with the crystalline lens 20 of surgical removal muddiness so that light arrive on the retinas 22 by pupil 18 in the clear.Cataractous lens is extractd by the otch that the top in cornea 12 and sclera 14 junctions 26 cuts out an approximate horizontal.
In case cataractous lens 20 usefulness surgical removal are fallen, light just can waltz through pupil 18 and pass on the retina 22.But, 20 very important light focusing functions of crystalline lens.Therefore, after crystalline lens 20 was extractd, the diopter of the visual system of eyes is " lacking " 20 degree approximately, and light no longer can correctly focus on the retina 22.When a crystalline lens 20 picked-off when eliminating cataract, must replace it with a prosthetic lens.After cataract surgery, focus on again on the retina 22 in order to make light, adopt an intraocular lens, all prior art intraocular lenss 28 as shown in Figure 2 usually.
Intraocular lens 28 can with any biologically be inert and be applicable to vision correction, make such as the transparent material of silicones.Crystalline lens 28 is intercepts of a spheroid, sees that from the front cardinal principle is rounded, and its diameter is about 6 millimeters.The a pair of tip 30 that touches plays a part on the tram in the back room that supporting leg or stable lasso be supported on crystalline lens 28 eyes 10 (Fig. 5).Each touches the tip 30 and stretches out about 4 millimeters, is stretched over the arc tips that is attached on the eyes from its rectilinear end that is attached to the periphery of crystalline lens 28.Like this, crystalline lens 28 and two overall widths that touch the tip 30 are about 14 millimeters.
Intraocular lens 28 is embedded in the rear of iris 16 as shown in Figure 5.Such crystalline lens is called posterior chamber phakic, it be up-to-date in many designs of intraocular lens also be the most general type.
Should be understood that the intraocular lens 28 of prior art can manufacture and adapt to back room other position in addition.For example, crystalline lens 28 can be placed in the anterior chamber, i.e. zone between cornea 12 and iris 16.But it is bad that such placement location is considered to sometimes, because the position that crystalline lens is placed on very near cornea may cause corneal endothelium wound to occur.
With the correct problem that links of implanting of intraocular lens be to determine to want after the operation the lenticular definite nominal light focal power in the implant patient eyes or the problem of diopter power exactly.Ophthalmologist or optometrist can for example manage to estimate the nominal light focal power of patient's natural crystalline lens 20 and by using various measuring devices, for example ultrasonic unit to measure the degree of depth and the diameter of eyes 10.These are measured in conjunction with clinical experience, make ophthalmologist or optometrist can determine the intraocular lens's 28 that will implant correct diopter or focal power more exactly.
But in some cases, although ophthalmologist or optometrist have been done maximum effort, the lenticular diopter that is placed in the eyes with surgical operation is not correct, and patient can not obtain good naked eyes visual acuity.Between the postoperative healing stage of surgery, patient's astigmatism degree changes, and has the refractive defects of knowing video that a kind of obstruction is focused into clear-cut.Some astigmatism that appear at after the cataract surgery are because the variation of the corneal curvature that operating otch and wound healing cause is caused.
The curvature of crystalline lens 28 can become asymmetrical, and the vertical meridian of eye that makes cutting line 3-3 along Fig. 2 shown in Figure 3 is visually than a little less than the horizontal meridian of eye of cutting line 4-4 along Fig. 2 shown in Figure 4 a little (diameter than small curve is bigger).Crystalline lens 28 remains unchanged at the thickness at center 28a place.Like this, the difference of the corresponding visual capacity of the vertical and horizontal meridian of eyeball be by eyeball vertical with horizontal meridian on different structure profile (for example different radius of curvature) 28b cause different ametropia characteristic generations respectively with 28c.Like this, crystalline lens 28 defines a spheroid intercept.Centering correctly in implanting eyes the time, two are touched the tip 30 and depart from vertical meridian respectively and stagger and be provided with and parallel with it.Like this, as mentioned above, 28 pairs of astigmatic focal powers of the intraocular lens of prior art only have fixed correcting value and angle value, and spherical focal power also is fixed.
This shows that the intraocular lens 28 of prior art has fixed astigmatism correction amount and fixed focal power.In Fig. 6 and 7, show an intraocular lens device 32, according to the present invention, this lens device disposes the device that is used for changing the device of lenticular focal power selectively and astigmatism correction is provided selectively.Lens device 32 comprises a central lens body 34 of being made by a kind of transparent flexible material, and this body is on the inner rim of its peripheral attachment to one by the ring of making than its hard material 36.The a pair of tip 30 that touches can be attached on this ring 36.
The actuating device that is a plurality of actuation body 38 forms is equally spaced round the circumference that encircles 36.Actuation body 38 can be attached on ring 36 the surface or be embedding in it when loop forming.The magnetizable material of actuation body 38 usefulness is made, and makes each single actuation body all play an effect with permanent magnet of north and south poles.If the actuation body of adjoining 38 is magnetized into the phase mutual repulsion, ring 36 will expand, and girth is increased, and causes the degree of convexity of lens body 34 to reduce, and therefore, its focal power also dies down.If the actuation body of adjoining 38 is magnetized into attract each other, ring 36 will shrink, and girth is shortened, and causes the degree of convexity of lens body 34 to increase, therefore, and its focal power grow.Like this, actuation body 38 just can adopt the shape of coming to control its focal power selectively after lens device 32 is implanted in the eyes and keeping selected lens body 36 till resetting.
Scattered-light degree can be easy to determine with conventional method.Thereby then an outside magnetic force is applied in the actuation body 38 expand on the predetermined actuation body or retraction ring 36 on produce required toroid configuration with the aligned part of astigmatism.
Magnetization actuation body 38 required magnetic force should be by force to being enough to prevent that crystalline lens 32 is reset under the situation of the normal intensity that is exposed to daily magnetic force.
In Fig. 8 and 9, show a substituted type embodiment of the present invention.Lens device 40 has a flexible central lens body 42 on the inner rim that is attached to a ring harder than it 44 on its periphery.A plurality of magnetizable actuation body 46 are equally spaced round ring 44, so that change focal power and astigmatism correction amount selectively as discussing in conjunction with lens device 32.But the part between actuation body 46 of ring 44 is compared with the part of adjoining of sealing actuation body, and has been attenuate on thickness.Like this, ring has just obtained additional flexible, thereby compresses this ring or make the required power of its shape of changing lens body of expanding just little.The a pair of tip 30 that touches can be attached on the ring 44.
The lens body 34 and 42 of the crystalline lens assembly shown in Fig. 6 to 9 have one towards the nonreentrant surface of pupil 18 and one towards after recessed surface.In addition, the second substituted type embodiment is illustrated among Figure 10 to 12 as the lens device 50 with protruding forward and backward surface.Lens body 52 be with a kind of transparent, the flexible material of tool is made slightly, its flat shape is that circular, side view is for oval.Periphery around body 52 is stretching an annular groove 54.Be provided with a ring 56 that is embedded with a plurality of magnetizable actuation body 58 in it in the groove 54.Attract each other or the phase mutual repulsion if all actuation body of adjoining all are magnetized into, ring 56 just will be distinguished contraction or expansion equally in all parts, so that change lenticular shape selectively, thereby change lenticular focal power.Equally, also can be that two or three actuation body of adjoining are magnetized to produce astigmatism correction, these actuation body can be to be positioned on the opposite end of diameter, in order to the correction rule astigmatism, as shown in figure 11, or be positioned on the end of diameter, in order to proofread and correct non-regular astigmatism, as shown in figure 12.A pair of actuation body 58a that adjoins and 58b are magnetized into and attract each other, and change the shape of crystalline lens 52 along the top in the cross section that 12-12 line among Figure 10 cuts thus.The a pair of tip 30 that touches can be attached on the ring 56.
The 3rd substituted type embodiment is illustrated on Figure 13 to 16 as the lens device 60 of the lens body 62 of a material (for example silicones) with the flexible or flexible on the ring 64 that releasably is attached to a hard material (such as PMMA).The a pair of tip that touches can be attached on the ring 64.The ring 64 on preceding surface 68, be formed with many circumferential grooves 66 of separating the different-diameter of distribution.Lens body 62 have be formed on its towards after surface 72 on circumferential joint tongue 70.Groove 66 and joint tongue 70 can make any suitable cross-sectional shape, such as illustrated trapezoidal shape, separate with ring 64 to prevent lens body 62 as long as groove can clamp joint tongue securely.The focal power of the lens body 62 of flexible or flexible can be by moving to joint tongue 70 the mode change selectively in suitable in the groove 66, that of outermost causes minimum focal power in the groove, and interior that then causes the highest focal power.Form with groove 66 by a plurality of interruptions or adjusting gap 74, can be implemented between groove and move.Similarly, with joint tongue 70 segmentations, each section is not more than the length in this gap corresponding to regulating gap 74 and its length on the position.
Lens device 60 presets any required focal power before can be in implanting eyes, and this can be by aiming at joint tongue 70 in the grooves 66 selected that and rotating lens body 62 with respect to ring 64 and realize so that joint tongue is embedded in this groove.If require to change focal power, can rotate lens body 62 and make each fan-shaped section of joint tongue 70 aim at, then joint tongue be moved on that select by required focal power in the groove 66, then joint tongue be rotated in the new selected groove with regulating gap 74.Whole joint tongue 70 can be made with a kind of material that magnetic is reacted, perhaps can be with an actuation body 76(Figure 16 who uses material that magnetic is reacted to make) be embedded on each fan-shaped section of joint tongue.Can adopt an external magnetic field to make each actuation body 76 motion.
In Figure 17 and 18, show the 4th substituted type embodiment of the present invention.Lens device 78 comprises a central lens body 80 on the inner rim that is attached to a ring harder than it 82 on its periphery.A plurality of magnetizable actuation body 84 are equally spaced round ring 82, in order to change focal power and astigmatism correction amount selectively.Actuation body 84 can with one in order to the shape that keeps lens device 78, be inlaid in together in the ring 82 such as shape keeper 86 such devices made from tinsel.Tinsel 86 circumferentially stretches by ring 82 between the neighboring of actuation body 84 and ring.Tinsel 86 adjoins at each the part between the actuation body 84 is inwardly stretched towards central lens body 80, and racing outwards forms V-arrangement then.As an external electric magnetic force is applied to this is moved with retraction ring 82 in opposite directions to actuation body, meanwhile, the V-shaped part adjoining between the actuation body on the tinsel 86 can narrow down.After removing external force, tinsel 86 can keep its new shape till the actuation body 84 of adjoining moves once more, also is like this even this does not have permanent magnetization to actuation body.Like this, all actuation body 86 can move to be compressed or the ring 82 that swells, thereby increases and reduce the focal power of lens device 78 respectively.In addition, can also actuate in the desired zone of lens device 78, to produce astigmatism correction selected actuation body 84.The example that ring 82 shrinks from shape shown in Figure 17 is illustrated in Figure 18.
In Figure 19, show the 5th substituted type embodiment of the present invention.Lens device 88 comprises the lens body 80 among the last embodiment, and this body also is on the inner rim that is attached to a ring 90 on its periphery.Be embedded with a plurality of actuation body 84 and shape keeper 86 in the ring 90.The neighboring 92 of ring 90 has the V-notch 94 of a plurality of formation V-shape portion position, that adjoin shape keeper 86 thereon, so that encircle the 90 pairs of compressions and easier the reacting that stretch.Like this, ring 90 flexible better, it is more smaller than previously described ring 82 to carry out the required power of contraction or expansion.
Figure 20 to 22 shows the 6th substituted type embodiment of the present invention.Lens device 96 has a flexible central lens body 98 on the inner rim that is attached to an internal ring 100 on its periphery.A plurality of magnetizable actuation body 102 100 are equally spaced round ring, in order to change focal power and astigmatism correction amount as top selectively discussing in conjunction with other crystalline lens assembly.But the neighboring of internal ring 100 is attached on the inner rim with shape keeper 104 setting-ins outer shroud 106 within it.Shape keeper 104 is represented more clearlyly in Figure 21, and it is shaped as tubular, and with concertina style elongation and shortening.When two actuation body of adjoining 102 in opposite directions or during opposing motion, internal ring 100 and outer shroud 106 promptly can be distinguished pucker ﹠ bloat.Shape keeper 104 also can contraction or expansion, and it is to keep the material of its state to make with a kind of before actuation body 102 forces its motion once more.Therefore, the shape hold facility of motion by actuation body 102 and shape keeper 104 promptly can be controlled the focal power and the astigmatism correction amount of crystalline lens 96.
Figure 23 shows the 7th substituted type embodiment of the present invention, and this embodiment is based on lens device shown in Figure 20 96.Lens device 108 has adopted lens body 98 recited above, internal ring 100, actuation body 102 and outer shroud 106.But shape keeper 104 is made spiral helicine wire form keeper 110 with one and is replaced, and this shape keeper promptly keeps this shape invariance later in case set its shape by the motion of actuation body 102.
Figure 24 shows a block diagram in order to the control system of handling the actuation body in above-mentioned each crystalline lens assembly.Power supply 112 has an outfan of receiving the input of a field intensity control device 114.An outfan of field intensity control device 114 is connected on first coil 116.Second outfan of field intensity control device 114 is connected on second coil 118. Coil 116 and 118 each can be contained on the support 120.This support can be any coil 116 and 118 to be pressed close to the suitable device that the relevant actuation body in any above-mentioned crystalline lens assembly is placed.Field intensity control device 114 can be regulated selectively and be applied to come up mode of operation according to a kind of crystalline lens assembly of the present invention of in the coil 116 and 118 each respectively with the electrical power with wide range and make relevant actuation body be subjected to permanent magnetization or just merely make its motion.Coil 116 and 118 can be one can with each actuation body single coil of spaced alignment sequentially, it also can be this coil of any other number, wherein each actuation body can be handled all actuation body in the lens device all to an independently coil should be arranged simultaneously.
As shown in figure 25, support 120 can form the part of device 122, in order to handle the actuation body of lens device of the present invention.Support 120 can be the ring with a central openings 124, and this perforate can be used for making device 122 and of the present invention a kind of crystalline lens assembly alignment of implanting in the human eye.Coil 116 and 118 is installed on the annular support 120, each coil be placed to lens device in a relevant actuation body in the actuation body that will be handled aim at.Schematically show the interpole coil 126 that is contained on the support 120 among the figure, its number can be the number of any needs.Coil 116 is received on any control device suitable, all field intensity control device 114 as shown in figure 24 by pair of lead wires 128.Equally, coil 118 is also received on the suitable control device by pair of lead wires 130.
By can being made by the polarity in coil 116 and 118 magnetic fields that produce, the electric current paraphase of flowing through associated tracks 128 and 130 swings to.Coil 116 and 118 can also dispose machinery with its orientation to handle actuation body selectively by required mode.For example, coil 116 can be installed on the support 132 that is clamped in slidably in the groove 134 on the face that is formed on support 124, that circumferentially stretch.Support 132 can move along groove 134 towards either direction so that coil 116 is located with respect to relevant actuation body exactly.In addition, the coil shown in the figure 118 is contained on the circular support 136 that is contained in rotationally on the support 120.Like this, the angle orientation change selectively on demand with respect to the radius of support 120 of coil 118.
Device 122 can be put in a kind of device, and patient can adopt this device to change the shape of lens body when situation needs.For example, device 122 can be packed in a pair of glasses or be made the control device that a hands is taken, by patient-operated to change the crystalline lens focal length between near vision and distance vision.
Figure 26 illustrates one and is used for the control device the automatically actuation body of any above-mentioned crystalline lens assembly of the present invention handled.Previously described power supply 112 is connected on the input of a control unit 138.The pair of output of control unit 138 is connected on the coil 116 and 118 that is installed on the support 120.Control unit 138 can include a general program control microprocessor, this microprocessor has a standard operation software system and one in order to receive the program of the instruction of being sent by the keyboard 140 on the input that is connected to control unit 138, the instruction of being sent is about be applied to the intensity of the electrical power on coil 116 and 118 and the instruction of persistent period from power supply 112, so that handle actuation body on demand.In addition, a position sensor 142 can be connected on the input of control unit 138, to produce a signal of representing support 120 and coil 116,118 with respect to the position of lens device to be handled.Position sensor 142 can be any device that is suitable for measuring any physical features on the lens device, normally light-sensitive unit.For example, position sensor 142 can detect the periphery of the actuation body shown in any aforesaid lens device embodiment, lens body or the periphery of ring.
Actuation body can be with a kind of ferromagnetic elements material or is used a kind of making in various alloy of ferromagnetic element that contiguous magnetic field is reacted and other element.In some cases, actuation element can still be in magnetized state even remove the external magnetic field, or arrange according to the arrangement of electromagnetic field simply by " forever " magnetization, has adopted the shape keeper in the case.
In general, provide a kind of rule or irregular astigmatism that after improved intraocular lens eliminates or reduces operation, occurs.The present invention adopts a kind of intraocular lens with a flexible central lens body, this central lens body by one have to such as the outer shroud of the actuation body of the external force sensitivity in magnetic field around.By the effect of outside magnetic force, lenticular shape is changed, crystalline lens is elongated correction of astigmatism along predetermined axis.If variation has taken place the astigmatism axle, can lenticular shape be changed by apply external force again along different axis.Also can adopt ring to change lenticular spheroid form and change its focal power.Adopt this intraocular lens, can make the cataract patient in the recovery from illness no longer need to wear glasses or contact lens.Exempt glasses or contact lens and bring great benefit can for the cataract patient in the recovery from illness, because the many people among them are old peoples, even if do not wear glasses or the burden of contact lens just has been enough difficulties.In addition, if necessary, the external force source can be put in a pair of glasses, perhaps puts in the device that a hands takes, and is handled selectively to adapt to different focal lengths by patient.
Though actuation body is described as being made by the ferrimagnet that magnetic field is reacted, this actuation body can be made by any suitable material that electromagnetic or mechanical energy waves is reacted, and these energy waves make circumferentially compression or expand of ring.
Various lens device recited above can be divided into " activity " (" active ") or " nonactive " (" passive ") system two classes." activity " system (32,40 and 50) need be applied to the field of force on the actuating device to change the shape of lens body selectively and reversibly.Actuating device is followed active real estate and is conigenous oneself shape of the field of force to keep selecting." nonactive " system also requires the field of force is applied on the actuating device to change the shape of lens body selectively and reversibly.But, the shape that its actuating device and keep without any need for the field of force is selected.Any actuating device of " activity " system among diagram and the described embodiment and any actuating device of " nonactive " system be mutual alternative on demand.In addition, any of illustrated actuating sections can be contained in relevant ring internal rotation with the coil 116 shown in Figure 25 and support 136 are the same.A kind of like this actuating sections can keep magnetized state, and can be made it to rotate the actuating sections that adjoins with attraction or repulsion or be oriented in neutral position by device 122.
In Figure 27 to 29, show the variable focal length intraocular lens device of a former actuating of micromotion of the present invention, this device indicates totally by label 32, and its crystalline lens disposes in order to the device that changes lenticular spherical focal power selectively with in order to the device of astigmatism correction to be provided selectively.Lens device 32 comprises the central lens body 34 that an a kind of clear flexible material such as silicones of usefulness is made.Lens body 34 is disc haply, and has and be suitable for aiming at the convex front face at eye pupil center and smooth rear surface.But front and rear surfaces can be the combination of concave surface, plane and the convex surface of any needs.Internal ring 36 by any suitable device, such as shown in figure 28 with the integrally moulded device that goes out of lens body, be attached thereto round the periphery of lens body 34.This internal ring or a plurality of internal ring 36 can be made with any suitable elastomeric material so that its periphery have suitable expansion and shrinkage thereby can become ellipse according to the former orientation of micromotion, segmentation is fan-shaped or the shape of waveform and so on.
Ring 36 is stretched by a plurality of radially inside centers towards lens body 34 and the separate micromotion that is arranged former 38 clamps.Micromotion former 38 respectively has a inner that is used for clamping internal ring 36 and one to be attached to outer end on the outer shroud 40 that stretches with one heart round internal ring 36.External support ring or installing ring 40 usefulness duroplastss or its material are made, and fixed support are provided for micromotion former 38 and lens body 34.The a pair of tip 30 that touches can be attached on the ring 40 lens device 32 is supported on the tram in the eyes.
As shown in figure 28, each micromotion former 38 can be made one and have a pair of fork thigh setting, almost parallel or supporting leg 42 and 44 of separating, and this diverges from a pedestal or a handle 46 that is attached on the outer shroud 40 to the fork thigh.Be formed with groove or sawtooth 48 and 50 respectively on the apparent surface of fork thigh 42 and 44. Groove 48 and 50 and a pair of opposed flange 52 and 54 synergism that are respectively formed on the internal ring 36 remains on the part of adjoining of lens body 34 and internal ring 36 apart from 40 1 selected distances of outer shroud.
If internal ring 36 expands, diameter is increased, the curvature of lens body 34 will diminish, and the focal power of crystalline lens assembly 32 is reduced.If internal ring 36 shrinks, make reduced, the curvature of lens body 34 will become greatly, and the focal power of crystalline lens assembly 32 is increased.Micromotion former 38 is selectively regulated to face lenticular focal power outside eyes with internal ring 36 synergism.Each micromotion former 38 can by one from not shown, give power such as the control signal of the extra power of the ultrasonic energy with predetermined in check frequency and amplitude, this control signal will make fork burst 42 and 44 vibrations, make it to vibrate along the direction of double-head arrow 58 and 60 respectively.This can produce the wave action that can cause flange 52 and 54 to move along the electing property of direction of double-head arrow 58 and 60 respectively.When fork thigh 42 and 44 moves horizontally separately, relevant flange 52 and 54 will be deviate from from groove 48 and 50 respectively, then be bonded on again in outer shroud 40 or nearer another grooves far away, this depends on outside in check frequency, has so just produced the propelling wave action along fork thigh 42 and 44 vertical.Micromotion former 38 can react to the various amplitude of ultrasonic energy: it can react to the ultrasonic energy of first preset frequency internal ring 36 is shunk, and the ultrasonic energy of second preset frequency is reacted expands internal ring 36.
Figure 29 illustrates a substituted type embodiment of micromotion former 38.Micromotion is former 38 ' shaping to be similar to micromotion former 38, but it includes linear orientation devices 64 that are arranged between two forks strands 42 and 44.Positioner 64 has a body 66 that at one end is attached on the pedestal 46.Bar 68 stretches out from the other end of body 66, and has a free end that is attached on the internal ring 36.The linear orientation device reacts expansion link 68 to a control signal from the extra power (not shown), thereby ring 36 is moved to change the shape of lens body 34 along the direction of arrow 62.The energy can be the ultrasonic energy recited above, also can be electromagnetic-energy (laser, radio wave, or the like).In two kinds of situations, be known with the conventional equipment of the linear motion 62 of this Conversion of energy.
If handle all micromotions former 38 and 38 ' internal ring 36 is held in circular configuration, then have only the focal power of crystalline lens assembly 32 to change.If the former shape of separately handling the relevant sections that changes lens body 34 of some micromotions just can selectively be proofreaied and correct astigmatism.Can be to former an actuating of micromotion to proofread and correct non-regular astigmatism, can be to two former actuatings of micromotion vis-a-vis with the correction rule astigmatism.Each micromotion former 38 and 38 ' can react to a different frequency activates to carry out selectivity, and in other words, each micromotion is former can be actuated selectively by the selective stimulating of outside.
Figure 30 to 33 illustrates another substituted type embodiment of the present invention.Lens device 70 has one at its peripheral attachment to one harder installing ring that is formed by a plurality of eclipsed arc segment or the flexible central lens body 72 on the support ring 74.Though three sections 76,78 and 80 only are shown among the figure, encircling 74 can be made of the sections of any suitable number.Ring 74 can be attached on the periphery of lens body 72 as described in conjunction with Figure 31 below, perhaps can pass the hollow marginal portion of lens body 72 as described in conjunction with Figure 32 below.The a pair of tip 30 that touches can be attached on the ring 74, and one of them touches the tip 30 and is attached on the sections 78, and another touches 30 at the tip and is attached on the sections 80.
Referring to Figure 31, the transverse section of overlapping sections 67,78 that micromotion of formation shown in the figure is former and 80 amplification.On the apparent surface of the lap of sections 76 and 80, respectively be formed with synergistic groove 82.On the apparent surface of the lap of sections 78 and 80, also respectively be formed with synergistic groove 84.Groove 82 and 84 allows to produce relative motion between the relevant sections selectively, and focal power and the astigmatism correction amount with lens device 70 is fixed on the selected numerical value thus, and this will illustrate below.
Referring to Figure 32, a part of lens device shown in the figure 70, wherein sections 76 and 78 overlaps, and to form a micromotion former.Respectively be formed with synergistic groove 86 on the apparent surface of the lap of sections 76 and 78, groove 86 allows to produce between the two segment relative motion selectively, and this will illustrate below.Sections 76 and 78 lap pass the hollow marginal portion 88 of lens body 72 slidably.
The lap of sections shown in Figure 31 and 32 and groove forms micromotion former 90 and 92 respectively.The element of these two a plurality of these classes of the former representative of micromotion, these elements can be separated setting round the periphery of crystalline lens 72 in micromotion shown in Figure 27 former 38 and 38 ' same mode.The micromotion that uses is former many more, and the curvature of lens body 72 is also even more, and the ability limit of regulating spheroid correction and astigmatism correction is accurate more.
Only need smaller sliding motion just can change the shape of lens body 72 between the eclipsed sections.A method that realizes this motion is to form groove 82,84 and 86, make the vibration of sections under first frequency can cause between the sections producing relative motion along a direction, the vibration under second frequency then can cause producing rightabout relative motion.This vibration can be brought out by the ultrasonic energy that applies from the outside.Another method that realizes this motion is to generate magnetic pole in sections, and these magnetic poles can be formed the pole pair of inhaling mutually or repelling each other as requested.Under any circumstance, groove allows to produce relative motion between the relevant sections selectively, and focal power and the astigmatism correction amount with lens device 70 is fixed on the selected numerical value thus.Acting on the exterior mechanical pressure that touches on the tip 30, can be used for triggering micromotion former so that eclipsed ridge edge produces circumferential movement.Have the ability of storage potential energy if micromotion is former, act on the exterior mechanical pressure that touches on the tip so and can adopt and discharge this energy or store this energy again.For example, the compression spring that is arranged in the positioner 64 just can be released or recompress.
Figure 33 illustrates a micromotion former 94 that is connected between internal ring 36 and the outer shroud 40.Micromotion former 94 has a central body 96, and this central body can be general cylindrical shape and be covered by pair of end walls 96a and 96b at its two ends.An end wall 96b of this body can be attached on the outer shroud 40.Stretch out one from the other end of body and have a bar 98a who is attached to the exposed junction on the internal ring 36.Bar 98a runs through end wall 96a and enters in the cylinder chamber 100a that is formed in the body 96.Piston 98b remains in the 100a of cylinder chamber and surperficial being attached on the butt end of bar 98a slidably thereon.Charged the compression fluid such as gas in the 100a of cylinder chamber, the gas on top, cylinder chamber has higher pressure, and this pressure forces piston 98b to move towards the lower end of cylinder chamber 100a.
Be formed with a memory 100b who charges the compressible fluid of pressurized with one heart round cylinder chamber 100a.The upper end of cylinder chamber 100a is connected to the upper end of memory 100b by a two-port valve 102a who is arranged in the end wall 96a.The lower end of cylinder chamber 100a is arranged on the lower end that two-port valve 102b in the body 96 and circumferentially extending path 10 4 that is formed in the end wall 96b are connected to memory 100b by one.Memory 100b is divided into two parts up and down by an annular piston 106.Piston 106 can react to the control signal such as the external power supply that is used to actuate and move downward, and is reduced in interior fluidic pressure and the fluidic pressure of increase in memory 100b lower part of upper part of memory 100b.Fluid will flow into the upper part of memory 100b from the upper part of cylinder chamber 100a by valve 102a, lower part from storage 100b flows into the lower part of cylinder chamber 100a by path 10 4 and valve 102b simultaneously, thereby forces piston 98b and bar 98a to move upward by direction shown in the arrow 108.Piston 106 moves upward and will cause piston 98b to do rightabout motion.This motion of piston 98b will cause producing relative displacement between internal ring 36 and the outer shroud 40, thereby cause the shape of lens body 34 to change.Thereby can also adopt the memory of other form, such as the flexible film that outside mechanical pressure is reacted, former or fluid is charged into again accumulate energy in the memory for future use to actuate micromotion.Exterior mechanical pressure be can use or micromotion former or valve 102a and 102b actuated such as the external trigger device of ultrasonic or laser, thereby perhaps for example by making fluid or gas expansion among the 100a of cylinder chamber accumulate energy for future use to fill energy to memory again.
Figure 34 illustrates an alternative embodiment of the invention.Micromotion former 110 has body 112, and this body is general cylindrical shape and has an end that is attached on the outer shroud 40.Bar 104 runs through the end wall that deviates from outer shroud 40 of body 112.The outer end of bar 114 is attached on the internal ring 36.The inner of bar 114 is then stretched in the central cavity 116 that an inside can be shaped on helical form groove or screw thread.One is shaped on externally threaded nut 118 and engages by the inwall of threaded engagement with hole 116.Nut 118 can react and rotates external power supply.Nut 118 is fix in position on bar 114, bar 114 will 116 longitudinal axis moves and moves along the direction of double-head arrow 120 along with the rotation of nut with along the hole, thereby produces the shape that relative motion changes lens body 34 between internal ring 36 and outer shroud 40.
Figure 35 illustrates another embodiment of the present invention.Micromotion former 122 has body 124, and this body can be any suitable shape, and its inner is attached on the internal ring 36.Micromotion former 122 comprises that also one is contained in body 124 and adjoins telecontrol equipment 126 on the outer end of outer shroud 40.A circular orbit device 128 was attached on the interior week of outer shroud 40, was formed with inside spiral type groove 130 on this rail set.Telecontrol equipment 126 can be any can moving so that the suitable device that lens body 34 is rotated round its center along groove 130, such as roller or endless-belt.Telecontrol equipment 126 can drive external power supply and control signal the mode with routine of reacting and rotate lens body 34 and move along the direction of double-head arrow 132, changes axial location and the sense focal power (functional power) of implanting the lens body 34 in the eyes thus.Micromotion former 122 the representative a plurality of can be by separating this class device of setting round internal ring 36 with micromotion shown in Figure 27 former 38 and 38 ' same mode.
If groove shown in Figure 35 35 is made into many cannelures rather than a single head helicla flute, and lens body 34 and a kind of flexible material of internal ring 36 usefulness make, and this just can carry out astigmatism correction.On the cell wall between the groove that adjoins, can be formed with the opening (not shown) that traverses cell wall, telecontrol equipment 124 can be walked about between these grooves.Have the different degree of depth if these grooves are made, each telecontrol equipment 124 just can move independently to select required groove, and the configuration that changes relevant portion on internal ring 36 and the lens body 34 thus is to provide astigmatism correction.
Adopt this intraocular lens of the present invention can make the cataract patient in the recovery from illness no longer need to wear glasses or contact lens.Exempt glasses or contact lens and bring great benefit can for the cataract patient in the recovery from illness, often more forgetful because the many people among them are old peoples, and also many people also have economically the difficulty with the health aspect.In addition, if necessary, the external force source can be put in a pair of glasses or a hands is taken in the device, selectively it is handled by patient; Perhaps micromotion is former can react so that focal length (focus) changes to applied pressure outside eyes, thereby makes crystalline lens have regulating power (from the ability as far as nearly change focal length).The present invention has the advantage that is better than prior-art devices, and it need not carry out connection entity or electric and change crystalline lens between power source and crystalline lens.
Variable forcus lens of the present invention also has various application except as the intraocular lens.For example, variable forcus lens can be used as camera lens.This crystalline lens can be in order to substitute or to use in conjunction with having fixed lens, adjustable camera lens or a plurality of len changeable camera gun.
In Figure 36 to 39, show the embodiment of the adjustable focal length intraocular lens device of various, the former actuating of micromotion of the present invention.In Figure 36, lens device indicates totally by label 32, and its crystalline lens disposes in order to change spherical focal power of lenticular sense and the device that astigmatism correction is provided selectively selectively.Lens device 32 comprises the central lens body 34 that an a kind of transparent flexible material such as silicones of usefulness is made.Lens body 34 is that roughly disc and having is adapted to aim at the nonreentrant surface at the center of eye pupil and the rear surface that can have spill, smooth or convex.The periphery 36 of lens body 34 can be formed by the internal ring that any suitable material is made, and thinks that actuation body provides a stable erecting device.For example, periphery 36 can be followed lens body 34 integrally moulded shapings, but cross section is thicker.
A plurality of micromotion former 38 inside center circumferentially extendings of separating setting towards lens body 34.Each micromotion former 38 all has one to be attached to the inner on the internal ring 36 and one and to be attached to outer end on the outer shroud 40 that stretches with one heart round lens body 34.Outer shroud 40 is to make with a kind of harder material, and it provides a fixed support for micro generator 38 and lens body 34.Outer shroud 40 is supported on lens device 32 on the tram in the eyes.
In Figure 36, suppose from the front, observe crystalline lens assembly 32 from the outside of eyes cornea, according to well-known optical principle, lens body 34 travels forward the lenticular sense focal power of increase towards observer's direction.Otherwise, the sense focal power that lens body 34 is moved backward and will be reduced crystalline lens assembly 32 towards the direction of optic nerve.Micromotion former 38 and internal ring 36 and outer shroud 40 synergism can selectively be regulated lenticular focal power from the eyes outside.Each micromotion former 38 can by one unshowned, provide power such as the extra power of the ultrasonic energy, this ultrasonic energy carries out work with such frequency, all micromotions former 38 are actuated promote equably lens body 34 along continuous straight runs forward, simultaneously lens body 34 is remained in the plane of approximate vertical, thereby cause the expansion action.The energy that applies a different frequency will make all micromotions former 38 be actuated to promote equably lens body 34 along continuous straight runs backward, simultaneously lens body 34 is remained in the plane of approximate vertical, thereby cause contractive action.
A radius 42 of lens device shown in Figure 36 32 outwards stretches the former 38a of micromotion that passes one of micromotion former 38 from the central point 44 of lens body 34.Lens body 34 round perpendicular at cornea 12 and look refreshing footpath 24(Fig. 5) between the plane of opticpath in any rotation of an axis can cause all that a kind of correction is scattered-light brings out astigmatic effect.If character is the non-regular astigmatism of segmenting (segmental) to be dropped on the position of radius 42 and lens body is made with flexible material, then can actuate the former 38a of micromotion one section of lens body 34 is bent with respect to the lens body remainder.More common astigmatism is the regular astigmatism of traversing optical axis fully.Can regulate backward or conversely with the former 38c of micromotion forward by actuating the former 38a of micromotion correction along the regular astigmatism of axis 46 orientation.
Before implanting crystalline lens in the eyes, can to lenticular optical characteristics measure and the data-storing of the combination of various actuating modes that for example relevant micromotion is former in computer, after in crystalline lens is implanted eyes, the data that are stored in the computer can the information behind surgical operation adopt the actuating of instructing micromotion former, to produce required diopter power and astigmatic correction.In order to proofread and correct non-rule and regular astigmatism and in order to proofread and correct the regulated quantity of diopter power, can by one by analyze information calculations from the following message source go out the former need of each micromotion with the computer program of actuating amount come the assisted control micromotion former, these information sources comprise: the axial length of the topography of cornea, the radius of curvature of cornea, refractive index, eyes and other eyes and lenticular data.
Figure 37 illustrates a substituted type embodiment of lens device 32.Lens device 48 comprises having the lens device 38 that is attached to the internal ring 36 on a plurality of micromotions former 38.The attachment arrangement of a pair of lasso 50 forms is attached on the lens body 34, and an end of each lasso 50 is attached on one relevant in the micromotion former 38.The working method of lens device 48 is the same with lens device 32.
Figure 38 illustrates another substituted type embodiment of the present invention.Lens device 52 comprises the lens body 34 on the end that its periphery 36 one of is attached in the micromotion former 38 that approximate horizontal stretches.On the end that the former other end of micromotion one of is attached in the supporting leg 30.Like this, micromotion former 38 can activated along the direction of arrow 54, thereby changes the focal power and the astigmatic focal power of lens body 34.
Referring to Figure 39, the amplification view of another substituted type of the present invention shown in figure embodiment.Lens device 56 comprises the lens body 34 of the end that its periphery 36 one of is attached in the micromotion former 38 that approximate vertical stretches.On the end that the other end of micromotion former 38 one of is attached in the supporting leg 30.Like this, micromotion former 38 can activated along the direction of arrow 58, thereby changes the focal power and the astigmatic focal power of lens body 34.The other end of micromotion former 38 is attached on the ring 36 by one armature assembly 62 if an end of micromotion former 38 is attached on the supporting leg 30 by armature assembly 60, and micromotion former 38 just can activated and stretch like that as shown in phantom in FIG. and along the arc-shaped path of movement shown in the arrow 64.
Figure 40 is one and is used to test and stores and will be used for selectively intraocular lens device 32 being positioned and the block diagram of the system 66 of directed data.Each controls the former actuating of each micromotion that is arranged in the lens device 32 dividually the former control device of micromotion 68.The former control device 68 of micromotion produces one and activates former required control signal of micromotion and power.Simultaneously, control device 68 sends index signal for computer 70, determines that those micromotions are former to activated.Being provided with an optical detection apparatus 72 is used for detecting the optical characteristics of lens device 32 and this information is offered computer 70.The optical information that computer 70 will come from checkout gear is with storing for future use from the control information of control device 68.
Figure 41 is one and it is located and the block diagram of directed system 74 selectively after being used in lens device 32 is implanted eyes.When needs change the sense focal power of lens device 32 and astigmatism correction is provided, computer 70 will provide required output signal to the former control device 68 of micromotion.68 pairs of information from computer 70 of the former control device of micromotion react, and produce one group of predetermined required suitable control signal and the power of the former combination of micromotion that activates in the lens device 32, to produce desired effect.
Not only the adjustment process that is described with reference to Figure 40 and 41 can for example be carried out in doctor's clinic or in medical institutions, and is used for selectively intraocular lens device being positioned with directed system offering patient's use.The former control device 68 of computer 70 and micromotion can be arranged in a pair of glasses frame, has the control device that is used by patient.When patient need to feel change official energy focal power, patient can put on this mirror holder, presses corresponding button, and intraocular lens device will automatically change.An example of Shi Yonging is like this: want to be transformed near vision so that carry out such as when reading or repairing the such low coverage work of clock and watch from distance vision patient, can provide this system of the present invention for patient, patient can be handled oneself regulating intraocular lens device, even can be adjusted to from 6 inches so near distances of workpiece good vision is also arranged.
Adopt this intraocular lens of the present invention, can make the cataract patient in the recovery from illness no longer need to wear glasses or contact lens.Exempt glasses or contact lens and bring great benefit can for the cataract patient in the recovery from illness, often more forgetful because the many people among them are old peoples, and also many people also have economically the difficulty with the health aspect.
Adjustable focal length crystalline lens of the present invention also has various application except as the intraocular lens.For example, the adjustable focal length crystalline lens can be used as camera lens.This crystalline lens can be in order to substitute or to use in conjunction with having fixed lens, adjustable camera lens or a plurality of len changeable camera gun.
According to the clause of Patent Law, the present invention is by thinking to have represented the content of the preferred embodiments of the present invention to be described.But, should be noted that the present invention can also implement and do not break away from the spirit and scope of the present invention by the mode that is different from herein concrete diagram and describe.

Claims (20)

1, a kind of intraocular lens device that is used to implant in the eyes is characterized in that including:
Limpid on optics, flexible, be circular and have the lens body of a periphery haply;
Harder ring with the inner rim on the described periphery that is attached to described lens body; With
Be attached to the actuating device on one of described lens body and described ring, this actuating device be used for reaching selectively the shape that reversibly changes described lens body and keep changing after shape with the feature of regulating this lens body, comprise focal power and astigmatic feature, described actuating device reacts to change described shape to the appearance of external fields of force.
2,, it is characterized in that described actuating device comprises a plurality of ferrimagnet actuation body that are equally spaced round the circumference of described ring according to the lens device of claim 1.
3, according to the lens device of claim 1, it is characterized in that including an annular groove on the described periphery that is formed on described lens body, described ring is arranged in this groove.
4, according to the lens device of claim 1, it is characterized in that described ring has at least two circumferential grooves that form within it, described lens body has formation joint tongue thereon, and this joint tongue and described groove synergism are attached to described lens body on the described ring.
5, according to the lens device of claim 1, it is characterized in that described actuating device comprises a plurality of ferrimagnet actuation body and shape keepers that are attached on the described ring that are equally spaced round the circumference of described ring, described actuation body reacts to change the shape after described shape and described shape keeper maintain described change to the appearance of external magnetic field.
6,, it is characterized in that comprising a control system of handling described actuating device according to the lens device of claim 1.
7, a kind of intraocular lens device that is used to implant in the eyes is characterized in that including:
Limpid on optics, flexible, be circular and have the lens body of a periphery haply;
Harder ring with the inner rim on the described periphery that is attached to described lens body; With
A plurality of actuation body that are attached on one of described lens body and described ring, shape after the change that these actuation body are used for reaching the shape that reversibly changes described lens body selectively and keeping this lens body with the feature of regulating this lens body, comprise focal power and astigmatic feature, described actuation body reacts to move the shape after described ring limits described change to the appearance of external fields of force.
8, a kind ofly be used to implant intraocular lens device in the eyes and a kind of, it is characterized in that including in order to handle this lens device with the focal power that changes this lens device and the control system of astigmatism correction amount:
Limpid, flexible central lens body on the optics;
Harder ring with the inner rim on the periphery that is attached to described lens body;
Be attached to the actuating device that electromagnetic energy is reacted on one of described lens body and described ring, this actuating device is used to change focal power and the astigmatism correction amount of this lenticular shape to regulate this lens body; With
One in order to produce a control system in the field of force of variation selectively that is used to handle described actuating device.
9, a kind of adjustable focal length intraocular lens device that is used to implant in the eyes is characterized in that including:
Transparent lens body with a periphery;
An installing ring that adjoins the described periphery setting of described lens body; With
Described installing ring is connected to the micromotion original device on the described periphery of described lens body, the control signal that described micromotion original device produces the outside reacts and realizes focal power and scattered-light correction with the shape of the described periphery that changes this lens body selectively and at least one among the position respectively to regulate lenticular focal length.
10, according to the lens device of claim 9, but it is characterized in that described periphery comprises the internal ring of a breathing, described installing ring comprises a harder outer shroud, and described micromotion original device is attached on the described outer shroud and releasedly with engagement of loops in described.
11, according to the lens device of claim 9, it is characterized in that described periphery and described installing ring are formed by a plurality of ring sections, described micromotion original device comprises the lap of described ring section.
12, according to the lens device of claim 9, it is characterized in that but described periphery comprises the internal ring of a breathing, described installing ring comprises a harder outer shroud, described micromotion original device is attached on the described outer shroud and releasedly with engagement of loops in described, and described micromotion original device has described control signal is reacted to activate described micromotion original device and to make described internal ring and outer shroud make the source of potential energy of relative motion.
13, a kind of adjustable focal length intraocular lens device that is used to implant in the eyes is characterized in that including:
Transparent lens body with a periphery;
The ring of the adjustable circumference on described periphery that is attached to described lens body; With
A plurality of micromotion original devices of separating setting and being connected thereto round described ring, the control signal that these micromotion original devices produce the outside reacts and realizes focal power and scattered-light correction with the circumferential length that changes described ring selectively to regulate lenticular shape.
14, according to the lens device of claim 13, it is characterized in that comprising a harder outer shroud, but described ring comprises the internal ring of a breathing, each described micromotion original device is made the form of a tuning fork, this tuning fork has the fork thigh of a pair of almost parallel, the fork thigh stretches out in the both sides of described internal ring and engages releasedly, and is connected on the pedestal that is attached on the described outer shroud.
15, according to the lens device of claim 13, it is characterized in that described ring is formed by multistage, each described micromotion original device comprises at least two described section lap.
16, according to the lens device of claim 13, it is characterized in that comprising a harder outer shroud, but described ring comprises the internal ring of a breathing, described micromotion original device is attached on the described outer shroud and releasedly with engagement of loops in described, and described micromotion original device has described control signal is reacted to activate described micromotion original device and to make described internal ring and outer shroud make the source of potential energy of relative motion.
17, a kind of adjustable focal length intraocular lens device that is used to implant in the eyes is characterized in that including:
Transparent lens body with a periphery;
An installing ring that stretches round the described periphery of described lens body; With
A plurality ofly be equally spaced and be attached on it and the micromotion original device that is connected with the described periphery of described lens body round described installing ring, each described micromotion original device reacts to external control signal and realizes focal power and scattered-light correction with the girth of the relevant portion of the described periphery that changes described lens body selectively and at least one among the axial location to regulate crystalline lens.
18, a kind of adjustable focal length intraocular lens device that is used to implant in the eyes is characterized in that including:
Transparent lens body with a periphery;
An attachment arrangement that is adjoining the described periphery of described lens body; With
Be connected the described periphery of described lens body ring and the micromotion original device between the described attachment arrangement, regulate the sense focal power and the astigmatism correction amount of the described lens body in the eyes with respect to eye's cornea and amphiblestroid position to change described lens body selectively thereby this micromotion original device reacts to external control signal.
19, a kind of adjustable focal length intraocular lens device that is used to implant in the eyes is characterized in that including:
Transparent lens body with a periphery;
An attachment arrangement that is adjoining the described periphery of described lens body; With
A plurality of described periphery and micromotions between the described attachment arrangement that are connected described lens body ring are former, thereby former external control signal is reacted of each micromotion regulated the sense focal power and the astigmatism correction amount of the described lens body in the eyes with respect to eye's cornea and amphiblestroid position with the relevant portion that changes described lens body selectively.
20, a kind of being used for selectively locatees and directed adjustable focal length intraocular lens system it after lens body is implanted eyes, it is characterized in that containing:
Transparent lens body with a periphery;
An attachment arrangement that is adjoining the described periphery of described lens body;
A plurality of described periphery and micromotions between the described attachment arrangement that are connected described lens body ring are former, thereby former external control signal is reacted of each micromotion regulated the sense focal power and the astigmatism correction amount of the described lens body in the eyes with respect to eye's cornea and amphiblestroid position with the relevant portion that changes described lens body selectively;
A control device that is used to produce described control signal in the eyes outside; With
A computer that is connected on the former control device of described micromotion, this computer sends the control data of required sense focal power regulated quantity of representative and astigmatism correction amount for described control device, and described control device reacts to produce described control signal to described control data.
CN 91109670 1991-03-11 1991-10-08 Intraocular lens with variable optical strength of astigmatism correction ability Pending CN1064611A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/667,671 US5108429A (en) 1991-03-11 1991-03-11 Micromotor actuated adjustable focus lens
US667,671 1991-03-11
US07/669,499 US5203788A (en) 1991-03-14 1991-03-14 Micromotor actuated adjustable focus lens
US669,499 1991-03-14

Publications (1)

Publication Number Publication Date
CN1064611A true CN1064611A (en) 1992-09-23

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ID=27099739

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 91109670 Pending CN1064611A (en) 1991-03-11 1991-10-08 Intraocular lens with variable optical strength of astigmatism correction ability

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Country Link
CN (1) CN1064611A (en)

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CN101203192B (en) * 2005-03-30 2010-09-15 纽镜有限公司 Adjustable intraocular lens assemblies and discrete components thereof
CN102196789A (en) * 2008-10-28 2011-09-21 庄臣及庄臣视力保护公司 Apparatus and method for activation of components of an energized ophthalmic lens
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US9182613B2 (en) 2008-10-28 2015-11-10 Johnson & Johnson Vision Care, Inc. Apparatus and method for activation of components of an energized ophthalmic lens
CN105247406A (en) * 2013-05-30 2016-01-13 庄臣及庄臣视力保护公司 An energizable ophthalmic lens device with a programmable media insert
CN105556348A (en) * 2013-08-13 2016-05-04 卡尔蔡司医疗技术股份公司 Eye lens having a specifically shaped transition region of an optical part
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US11464622B2 (en) 2013-11-01 2022-10-11 Lensgen, Inc. Two-part accommodating intraocular lens device
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CN101203192B (en) * 2005-03-30 2010-09-15 纽镜有限公司 Adjustable intraocular lens assemblies and discrete components thereof
CN102196789A (en) * 2008-10-28 2011-09-21 庄臣及庄臣视力保护公司 Apparatus and method for activation of components of an energized ophthalmic lens
CN102196789B (en) * 2008-10-28 2014-11-05 庄臣及庄臣视力保护公司 Apparatus and method for activation of components of an energized ophthalmic lens
US9182613B2 (en) 2008-10-28 2015-11-10 Johnson & Johnson Vision Care, Inc. Apparatus and method for activation of components of an energized ophthalmic lens
CN104127261A (en) * 2013-05-03 2014-11-05 天津晶明新技术开发有限公司 Adjustable artificial lens and contact lens
CN105247406A (en) * 2013-05-30 2016-01-13 庄臣及庄臣视力保护公司 An energizable ophthalmic lens device with a programmable media insert
CN105556348A (en) * 2013-08-13 2016-05-04 卡尔蔡司医疗技术股份公司 Eye lens having a specifically shaped transition region of an optical part
CN105556348B (en) * 2013-08-13 2018-01-12 卡尔蔡司医疗技术股份公司 The eye lens of the transitional region of specially-shaped with optical element
CN105765414A (en) * 2013-09-27 2016-07-13 艾亮有限公司 Improvements in or relating to deformable membrane assemblies
CN105765414B (en) * 2013-09-27 2017-08-11 艾亮有限公司 The improvement of deformable film component or the improvement for being related to deformable film component
US11464622B2 (en) 2013-11-01 2022-10-11 Lensgen, Inc. Two-part accommodating intraocular lens device
US11464624B2 (en) 2013-11-01 2022-10-11 Lensgen, Inc. Two-part accommodating intraocular lens device
US11471273B2 (en) 2013-11-01 2022-10-18 Lensgen, Inc. Two-part accommodating intraocular lens device
CN110236737B (en) * 2014-07-31 2021-12-14 雷恩斯根公司 Accommodating intraocular lens device
US11464621B2 (en) 2014-07-31 2022-10-11 Lensgen, Inc. Accommodating intraocular lens device
CN110236737A (en) * 2014-07-31 2019-09-17 雷恩斯根公司 Adjust intraocular lens body device
US11826246B2 (en) 2014-07-31 2023-11-28 Lensgen, Inc Accommodating intraocular lens device
US11471270B2 (en) 2015-12-01 2022-10-18 Lensgen, Inc. Accommodating intraocular lens device
CN109069266B (en) * 2016-05-02 2021-09-21 G·巴尔齐莱 Intraocular lenses and methods and/or assemblies related thereto
CN109069266A (en) * 2016-05-02 2018-12-21 G·巴尔齐莱 Intraocular lens and associated method and/or component
CN109481084B (en) * 2018-10-30 2021-02-09 田东华 Ophthalmic lens with thin film coating
CN109481084A (en) * 2018-10-30 2019-03-19 田东华 A kind of ophthalmic lens with film coating
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