CN106073828B - A kind of detection of intraductal ultrasonography and therapeutic device - Google Patents
A kind of detection of intraductal ultrasonography and therapeutic device Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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- A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
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- A61N7/022—Localised ultrasound hyperthermia intracavitary
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Abstract
The present invention proposes that a kind of intraductal ultrasonography detects and therapeutic device, the device include pipe end of probe and background process equipment.Pipe end of probe includes high-power transmitting probe, soft pipe, thin-film covering, highly sensitive receiving transducer array, entrant sound flow container, mechanical control unit, signal processing unit and communication unit.High-power transmitting probe emits ultrasonic wave in vitro, ultrasonic wave travels to intracorporeal organ along the entrant sound liquid in soft pipe, again by the highly sensitive receiving transducer array received being inserted into intracorporal thin-film covering after detection, received detection data is transferred to background process equipment processing display and is supplied to diagnosis.In addition increasing transmission power also directly can carry out ultrasonic therapy to certain lesions.The present invention realizes Global-Coupling or locally coupled or point coupling using different thin-film coverings for different detection positions, it is practical, oesophagus, tracheae and part internal organs can be carried out with internal ultrasound detection and treatment, three-dimensional scan data can carry out quantitative analysis to illness.
Description
Technical field
The present invention relates to ultrasonic medicals and ultrasonic detecting technology, and in particular to a kind of to enter intracorporal ultrasound detection and treatment
Device.
Background technique
Medically, since ultrasonic wave is to the innocuousness of human body, ultrasonic detection technology is widely used in tissue topography's inspection
It surveys, the diagnosis of organ lesion, judges the degree of mobility of blood vessel, fetus growth situation identification etc., doctor can see in advance
The lesion situation of inside of human body tissue, diagnoses, treated as soon as possible ahead of time.It can also make human body furthermore with the huge energy of ultrasonic wave
Interior calculus is done violent forced vibration and is crushed, to slow down slight illness, achievees the purpose that healing.In addition to this, ultrasound is utilized
The high-energy of wave can also destroy bacterial structure, carry out sterilizing.Utilize the fuel factor and mechanical effect of the lower ultrasonic wave of intensity
It answers, " heating " and mechanical stimulus is carried out to disease location with focusing or non-focusing acoustic beam to treat certain diseases, to promotion wound
Healing and the absorption of tumour etc. have preferable effect.
Above ultrasound diagnosis and ultrasonic medical, all detection devices of ultrasound are all in vitro.Ultrasonic wave is in vitro
Transmitting is received by external reception device, path length experienced again after tissue reflects, and interferes more, received echo
It is faint, influence detection accuracy.And ultrasonic wave from vitro pass in vivo, often because bone block or certain organ gas
The influence of bubble and can not detect.If detection device can be extend into vivo will overcome this deficiency.
Currently without intracorporal ultrasonic medical device is protruded into, it is only extend into the optical detection device checked in vivo, referred to as
Endoscope has different endoscopes for the different application scenarios of different organs.Such as, there are oesophagoscope, bronchoscope etc..For
Oesophagus, oesophagoscope are the important tools for carrying out foreign body in esophagus folder, esophagus detecting and other important operations, mostly soft using fiber now
Matter oesophagoscope, it uses electronic CCD (charge coupled cell) optical system, external camera shooting central host and cold light source host energy
Doctor's clearly CCD image is provided, various surgical instruments are cooperated, doctor can go deep into oesophagus, carry out alimentary canal hand
Art helps doctor to check and diagnose.Such method obtains detectable substance surface image, Yi Shengju by the irradiation principle of optical frames
This by virtue of experience carrys out the subjective judgement state of an illness, and could not obtain the data of detectable substance interior tissue, to not can be carried out quantitative point
Analysis.And to enter the intracorporal instrument of human body relatively more for this method, and additional injury is brought to the organ of patient, increases the pain of patient
It is bitter.
Front is also mentioned ultrasound and tissue topography can be imaged, can also be right if ultrasonic probe can be inserted into vivo
The imaging such as internal organ, tracheae, oesophagus, from without the use of optical frames.If but ultrasonic probe transmitting and receiving transducer (or transceiver
Probe) be all inserted into vivo, make whole system huge since transmitting probe is generally large in size, insertion is difficult.Have specially
Benefit " esophagoscope system (the application number: 201010614344.3) " that medical color is more with color Doppler ultrasonic scanning function
The general endoscopic system strangling ultrasonic probe and being used in combination with soft oesophagoscope.This method is that soft fibre food is inserted into esophageal patient
The probe working tips of Guan Jing, Color Doppler ultrasound probe enter oesophagus through the instrument channel of soft fibre oesophagoscope, to food
Tube wall and surrounding tissue are scanned, and thus obtain the data that can carry out the organ-tissue of quantitative analysis.This method is to eat
Flow with Color Doppler Ultrasound System is added on the basis of Guan Jing, therefore more into the intracorporal instrument of human body, to the organ band of patient
Carry out additional injury, increases the pain of patient.The image of oesophagus can also be obtained by being inserted into intracorporal ultrasonic probe in fact, so as to
Endoscopic system need not be used.
If directly supersonic sounding can be applied to (in pipeline), can both to have obtained three-dimensional detection figure in body in real time
Picture is to realize the function of endoscope in addition to surface is there are also tissue surface structural images below；Also available organ group
Careful three-dimensional detection data is knitted, and then its lesion is carefully analyzed and divided, the case where not using optical frames
The lower effect for promoting endoscope.It is easier to generate energy using its fuel factor and mechanical effect in addition, protruding into intracorporal ultrasound
Expectoration absorbs tumour etc., treats certain diseases with this.
Summary of the invention
It is diagnosed for current ultrasound and ultrasonic medical is all based on external transmitting and received, reception weak output signal, and is right
Oesophagus, tracheae and part internal organs detection difficult, and endoscope obtains image using optical principle, it is difficult to carry out organ group
The quantitative analysis etc. knitted.The present invention proposes a kind of detection of intraductal ultrasonography and therapeutic device, emits powerful ultrasonic wave in vitro,
Ultrasound travels in vivo along the entrant sound liquid in soft pipe, is connect again by being inserted into intracorporal highly sensitive receiving transducer array after detection
It receives, received detection data is transferred to background process equipment processing display again and is supplied to diagnosis.In addition when increase is sent out
Penetrate power directly can also carry out ultrasonic therapy or physical therapy to certain lesions in vivo.
The purpose of the present invention is realized at least through one of following technical solution.
A kind of detection of intraductal ultrasonography and therapeutic device, including pipe end of probe and set by host, operation keyboard or hand-held
The background process equipment of standby and its display composition；Pipe end of probe includes high-power transmitting probe, entrant sound flow container, soft pipe, thin
Membrane cover, highly sensitive receiving transducer array, mechanical control unit, signal processing unit and communication unit, end of probe pass through communication unit
Member is communicated with background process equipment；The head end of the soft pipe is connected with high-power transmitting probe, and other end, that is, end is cased with
Thin-film covering, is provided with the external port being connected with entrant sound flow container near the head end of soft pipe, and entrant sound flow container passes through external when work
Entrant sound liquid is injected to soft pipe in port；The highly sensitive receiving transducer array is attached on thin-film covering inner wall；The Mechanical course list
Member control is inserted into intracorporal soft pipe, thin-film covering, highly sensitive receiving transducer array and is moved together, and movement includes insertion, rise, under
Drop and rotation；The signal processing unit be mainly responsible for the signal that background process equipment transmits is cached, digital-to-analogue conversion, function
Rate control and power amplification carry out preposition amplification, analog-to-digital conversion and caching to the signal of highly sensitive receiving transducer array received.
Further, the communication unit is responsible for the wireless communication or wired between pipe end of probe and background process equipment
Communication.
Further, the highly sensitive receiving transducer array is the array of receiving transducer composition.
Further, when thin-film covering uses uniform thickness, receiving transducer is uniformly placed inside entire thin-film covering.
Further, thin-film covering uses thickness heterogeneous, places receiving transducer in thin place, receiving transducer is capacitor
It declines and processes ultrasonic probe or film-type probe.
Further, soft tube wall applies non-acoustic window material, so that ultrasound is only propagated inside soft pipe；The entrant sound liquid
Entrant sound liquid is kept in inside tank；The thin-film covering is made of acoustic window material.
Further, the high-power transmitting probe is powerful piezoelectric ceramic transducer, sends ultrasonic wave.
Further, entrant sound flow container by the external port of soft pipe injects entrant sound liquid, entrant sound towards soft pipe at work
Liquid reaches thin-film covering along soft pipe, and thin-film covering expansion becomes larger, the highly sensitive receiving transducer array being arranged on thin-film covering inner wall
It is close to detection position, each receiving transducer of highly sensitive receiving transducer array is in the different position in space；When thin-film covering is equal
When even thickness, thin-film covering can in large area with detection position Global-Coupling；When thin-film covering non-uniform thickness, then thin-film covering expands
At irregular shape, thin place protrusion, thin-film covering and detection position is locally coupled or point coupling.
Further, the cable between the receiving transducer and signal processing unit of the highly sensitive receiving transducer array
For thin wire, along the inner tubal wall of soft pipe and the inner wall arrangement of thin-film covering, when work soft pipe and thin-film covering be filled with entrant sound liquid,
Entrant sound liquid is the material of insulation, such as edible oil.
Further, entrant sound flow container, mechanical control unit, signal processing unit, the communication unit of the pipe end of probe
It is located at external, mechanical control unit, signal processing unit, communication unit and high-power transmitting probe collection with high-power transmitting probe
On Cheng Yi block plank；The end of soft pipe, thin-film covering and highly sensitive receiving transducer array be inserted into when working intracorporal tracheae or
Person's esophagus.
Cable between the receiving transducer and signal processing unit of the highly sensitive receiving transducer array of above-mentioned pipe end of probe
For thin wire, along the inner tubal wall of soft pipe and the inner wall arrangement of thin-film covering, when work soft pipe and thin-film covering be filled with entrant sound liquid,
Therefore entrant sound liquid selects the material of insulation, such as edible oil.
Further, there are two types of operating modes for the intraductal ultrasonography detection and therapeutic device, first is that detection pattern, detector
The pathological condition of official；Second is that treatment mode, carries out ultrasonic therapy.Wherein detection pattern, the one-time detection process at some position are as follows:
(1) soft pipe is inserted into the organs such as intracorporal tracheae or esophagus with thin-film covering and highly sensitive receiving transducer array,
Thin-film covering is flat at this time；
(2) entrant sound liquid is injected.Entrant sound liquid inside entrant sound flow container is injected soft pipe by the external port of soft pipe, and
Thin-film covering is reached along soft pipe, so that thin-film covering expansion becomes larger, last entrant sound liquid is full of soft pipe and thin-film covering；
(3) external acoustically-driven.Background process equipment determines the transmission power of ultrasound detection signal, is sent to by communication unit
Signal processing unit；Signal processing unit carries out digital-to-analogue turn by the signal that send that communication unit transmits to background process equipment
It changes with after corresponding power amplification, ultrasonic wave transmission is carried out by high-power transmitting probe, ultrasonic wave passes through soft pipe and thin-film covering
Interior entrant sound liquid reaches film jacket wall, is close to due to thin-film covering using acoustic window material and after expanding with detection position, couples, because
This ultrasonic wave easily propagates through film jacket wall and reaches detection position；
(4) reflecting ultrasonic wave for detection position is received.Ultrasonic wave reaches detection position, after testing position lower-hierarchy
Reflection forms back wave, and each receiving transducer of the highly sensitive receiving transducer array in thin-film covering receives a back wave,
It is converted into electric signal, signal processing unit is reached by thin wire.Multiple receiving transducers receive signal processing unit by multiple
Reflection wave groups at one group of signal, signal processing unit amplification preposition to this group of signal, analog-to-digital conversion and caching, later again by leading to
Letter unit is transmitted to background process equipment.
(5) processing of background process equipment and imaging display.The data that background process equipment receives be multiple spatial positions not
Multiple back waves of same receiving transducer acquisition, and due to the highly sensitive receiving transducer battle array in background process equipment known film set
The position of each receiving transducer is arranged, therefore obtains the three-dimensional imaging that this position is this time detected after being handled.
It is to be set by controlling background process furthermore it is also possible to carry out the detection of different directions to the same detection position
Standby operation keyboard or hand-held equipment, and then this control command is transmitted to mechanical control unit by communication unit, by machinery
The intracorporal soft pipe rotation of control unit control insertion, and then thin-film covering and highly sensitive receiving transducer array rotation are driven, then weigh
Multiple (3) (4) (5).The three-dimensional imaging of different directions can be spliced into relatively sharp rotatable three by known location
Tie up three-dimensional imaging.The detection at next position is carried out, then passes through the operation keyboard or hand-held equipment of background process equipment
Control, moves up and down the position of soft pipe, reaches next detection position, repeat (3) (4) (5).
Treatment mode can be enabled when certain positions need to carry out ultrasonic therapy.This mode needs to increase ultrasonic signal
Transmission power, so that the ultrasonic wave of high-power transmitting probe transmitting passes through the entrant sound liquid in soft pipe and thin-film covering and reaches therapy section
Position, and then carry out ultrasonic therapy.When having phlegm such as esophagus, transmission power can be increased to achieve the purpose that ultrasonic resolving sputum.
Its course of work can are as follows: detects that some position has exception directly to increase ultrasound when needing to treat in detection pattern
The transmission power of signal to carry out ultrasonic therapy to the position.It is also possible to enable detection pattern not yet, directly arrives treatment mould
Formula, process are as follows:
(1) soft pipe is inserted into the organs such as intracorporal tracheae or esophagus with thin-film covering and highly sensitive receiving transducer array；
(2) entrant sound liquid is injected.Entrant sound liquid inside entrant sound flow container is injected soft pipe by the external port of soft pipe, and
Thin-film covering is reached along soft pipe, so that thin-film covering expansion becomes larger, last entrant sound liquid is full of soft pipe and thin-film covering；
(3) external acoustically-driven.Background process equipment determines ultrasonic therapy signal transmission power, is sent to letter by communication unit
Number processing unit；Signal processing unit carries out digital-to-analogue conversion by the signal that send that communication unit transmits to background process equipment
After corresponding power amplification, ultrasonic wave transmission is carried out by high-power transmitting probe；
(4) internal ultrasonic therapy.The ultrasonic wave of high-power transmitting probe transmitting passes through the entrant sound in soft pipe and thin-film covering
Liquid reaches therapentic part, carries out ultrasonic therapy；
The treatment of different directions can be carried out to the same therapentic part after the completion of the seance process at some position,
It is the operation keyboard or hand-held equipment by controlling background process equipment, and then this control command is passed by communication unit
It to mechanical control unit, is rotated by the intracorporal soft pipe of mechanical control unit control insertion, and then drives thin-film covering and highly sensitive
Receiving transducer array rotation repeats (3) (4).The treatment at next position is carried out, then passes through background process equipment
Keyboard or the control of hand-held equipment are operated, the position of soft pipe is moved up and down, reaches next therapentic part, repeat (3) (4)
?.
Above-mentioned detection pattern and treatment mode at work directly alternately can be not required to take out soft pipe.If examining
Discovery needs to treat in survey mode, then operator is switched to treatment mode, and transmission power is changed to carry out ultrasound to the position
Treatment.If discovery needs to detect in treatment mode, operator is switched to detection pattern, changes transmission power and comes to the portion
Position carries out ultrasound detection；
After above-mentioned detection or treatment are completed, with an absorption plant entrant sound liquid from thin-film covering and soft pipe interior suction
Out, thin-film covering is deflated becomes smaller, then with the taking-up of the soft pipe of thin-film covering and highly sensitive receiving transducer array.
Compared with prior art, the invention has the following advantages that
(1) present invention is directly applied to supersonic sounding in body (in pipeline), with external supersonic sounding medical treatment skill
Art is compared, and is greatly shortened reflected ultrasonic wave to the distance of receiving transducer, is greatly improved the intensity for receiving signal, therefore letter can be improved
It makes an uproar and compares, improve detection accuracy.
(2) the careful three-dimensional detection data of the available organ-tissue of the present invention, is in addition to there are also the tissues on surface
Surface structure organization image below, and then its lesion is carefully analyzed and divided, the case where not using optical frames
The lower effect for promoting endoscope.
(3) present invention realizes Global-Coupling or locally coupled or point using different thin-film coverings for different detection tissues
Coupling, coupling is good so that interference when supersonic sounding tissue by other bubbles etc. is small, improves detection accuracy, while practical.
(4) receiving transducer of highly sensitive receiving transducer array that the present invention uses is small in size, can inside thin-film covering cloth
Many receiving transducers are set, receiving transducer is conducive to high-precision imaging more.
(5) present invention increases transmission power can carry out ultrasonic therapy in vivo.The ultrasound of high-power transmitting probe transmitting
It treats entrant sound liquid of the signal in soft pipe and thin-film covering and reaches therapentic part, carry out ultrasonic therapy.Protrude into intracorporal ultrasound
Device can also carry out the spraying of drug by the way, it is easier to utilize its fuel factor and mechanical effect, generate energy and carry out expectoration, absorb
Tumour, and be conducive to the organ-tissue absorption of drugs etc. for the treatment of.
(6) device of the invention for protruding into patient's body is smaller and few, can mitigate the sense of discomfort of patient；In addition in addition to answering
Human body is used, also can be applied to other organisms.
Detailed description of the invention
Fig. 1 is the schematic diagram of the present embodiment intraductal ultrasonography detection device.
Fig. 2 is the schematic diagram of the present embodiment intraductal ultrasonography detection device pipe end of probe.
Fig. 3 is the structural schematic diagram of the present embodiment intraductal ultrasonography detection device.
Schematic diagram when Fig. 4 a is the thin-film covering work expansion of the uniform thickness of the present embodiment intraductal ultrasonography detection device.
Signal when Fig. 4 b is the thin-film covering work expansion of the non-uniform thickness of the present embodiment intraductal ultrasonography detection device
Figure.
Fig. 5 is the use schematic diagram of the pipe end of probe of the present embodiment intraductal ultrasonography detection device.
Fig. 6 is the course of work of the present embodiment intraductal ultrasonography detection method detection pattern.
Fig. 7 is the course of work of the present embodiment intraductal ultrasonography detection method treatment mode.
Fig. 8 is the work flow diagram of the present embodiment intraductal ultrasonography detection method.
Specific embodiment
Specific embodiments of the present invention will be further explained with reference to the accompanying drawing, but implementation of the invention is not limited to
This.
As shown in Figure 1, being a kind of schematic diagram of intraductal ultrasonography detection device described in the present embodiment.A kind of intraductal ultrasonography detection
Device includes pipe end of probe 1 and by host (ultrasound system mainframe can be used), operation keyboard or hand-held equipment (such as manipulator
Handle) and its display composition background process equipment 2.Pipe end of probe be responsible for detection acquisition data, background process equipment be responsible for pair
The data of acquisition carry out processing imaging display and human-computer interaction.Host is responsible for the control of whole system, operates keyboard or hand-held behaviour
It is mainly the input equipment of host as equipment and the insertion position of pipe end of probe is controlled, display is mainly aobvious to setting parameter
Show and the imaging of detection data is shown.Pipe end of probe and background process equipment can be by wired or wirelessly connect
It connects, illustrates wireless connection type.
As shown in Fig. 2, being a kind of schematic diagram of intraductal ultrasonography detection device pipe end of probe described in the present embodiment.Pipe end of probe
1 includes high-power transmitting probe 11, soft pipe 12, thin-film covering 13, highly sensitive receiving transducer array 14, entrant sound flow container 15, machinery
Control unit 16, signal processing unit 17 and communication unit 18.Wherein high-power transmitting probe 11 is powerful piezoelectric ceramics
Energy converter sends ultrasonic wave；Entrant sound liquid is kept in inside entrant sound flow container 15；Soft 12 one end of pipe (head end) and high-power transmitting probe
Connection, other end (end) is thin-film covering, and an osculum (referred to as external port) and entrant sound liquid tank hose are opened near head end
It is connected, soft tube wall applies non-acoustic window material, and the 19 entrant sound flow container of switch valve that when work opens entrant sound flow container passes through external port
Entrant sound liquid is injected to soft pipe, so that ultrasound is only propagated inside soft pipe, the size of soft pipe is according to the size of sense organ
Tube wall is selected to apply non-acoustic window material；13 sets of the thin-film covering ends in soft pipe, highly sensitive receiving transducer array 14 are receiving transducer
The array of composition is attached on 13 inner wall of thin-film covering；Receiving transducer can be the multiclass such as capacitance type micromachined ultrasonic probe or film
The probe of type.The control of mechanical control unit 16 is inserted into intracorporal soft pipe, thin-film covering, highly sensitive receiving transducer array one and is started shipment
It is dynamic, including insertion, up and down and rotation.Signal processing unit 17 be background process equipment is transmitted to send signal
Caching, DA, power control and power amplification, and preposition amplification, AD are carried out to the signal of highly sensitive receiving transducer array received
And caching.Communication unit 18 is responsible for the wireless communication between background process equipment or provides wired communication interface.Greatly
Power emission probe 11, mechanical control unit 16, signal processing unit 17 and communication unit 18, which integrate, to be fixed on one piece of plank.
As shown in figure 3, being a kind of structural schematic diagram of intraductal ultrasonography detection device described in the present embodiment.Background process
Equipment determines the transmission power of ultrasound detection signal and sends signal, is sent to signal processing unit by communication unit；In addition
The operation keyboard of background process equipment or the sending control command of hand-held equipment, are transmitted to Mechanical course list by communication unit
Member is inserted into intracorporal soft pipe with thin-film covering and highly sensitive receiving transducer array to the position of determination by mechanical control unit control
It sets；Signal processing unit carries out digital-to-analogue conversion and corresponding by the signal that send that communication unit transmits to background process equipment
After power amplification, ultrasonic wave transmission is carried out by high-power transmitting probe.Ultrasonic wave reaches detection position (detection tissue), by inspection
The reflection of position lower-hierarchy is surveyed, back wave, each receiving transducer of the highly sensitive receiving transducer array in thin-film covering are formed
A back wave is received, electric signal is converted into, signal processing unit is reached by thin wire.Multiple receiving transducers make at signal
Reason unit receive by multiple reflection wave groups at one group of signal, signal processing unit is to the preposition amplification of this group of signal, analog-to-digital conversion
And caching, background process equipment is transmitted to by communication unit again later.The data that background process equipment receives are multiple spatial positions
Multiple back waves of different receiving transducer acquisitions, and due to the highly sensitive receiving transducer in background process equipment known film set
The position of each receiving transducer of array, therefore the three-dimensional imaging that this position is this time detected is obtained after being handled.
It is a kind of intraductal ultrasonography detection device pipe end of probe thin-film covering work described in the present embodiment as shown in Fig. 4 a, Fig. 4 b
When the schematic diagram that expands.13 sets of the thin-film covering ends in soft pipe of pipe end of probe, thin-film covering can be adopted according to the needs of application
With thickness uniform or heterogeneous.Thin-film covering uses uniform thickness, then uniformly places to receive inside entire thin-film covering and visit
Head；Using thickness heterogeneous, then receiving transducer is placed in thin place.Diagram 4a illustrates thin-film covering using uniform thick
Degree, diagram 4b illustrate thin-film covering using thickness heterogeneous.Entrant sound flow container passes through the external port court of soft pipe at work
Soft pipe injects entrant sound liquid, and entrant sound liquid reaches thin-film covering along soft pipe, and thin-film covering expansion becomes larger, is arranged on thin-film covering inner wall
Highly sensitive receiving transducer array and detection position be close to, each receiving transducer of highly sensitive receiving transducer array is in space not
Same position.When thin-film covering uniform thickness (diagram 4a), thin-film covering can in large area with detection position Global-Coupling；When thin
When Membrane cover non-uniform thickness (diagram 4b), then thin-film covering is expanded into irregular shape, thin place protrusion, thin-film covering and detection
Position is locally coupled or point couples.
In from the graph it can be seen that, the receiving transducer and signal processing list of the highly sensitive receiving transducer array of pipe end of probe
Cable 110 between member is thin wire along the inner tubal wall of soft pipe and the inner wall arrangement of thin-film covering, when work soft pipe and thin
Membrane cover is filled with entrant sound liquid, therefore entrant sound liquid selects the material of insulation, such as edible oil.
As shown in figure 5, being a kind of use schematic diagram of intraductal ultrasonography detection device pipe end of probe described in the present embodiment.Such as inspection
Oesophagus is surveyed, patient lies low, does appropriate position, be put into eyelid retractor and fixation to patient oral cavity portion, work be ready, then to trouble
Person's oesophagus is slowly inserted into soft pipe, and soft pipe 12 is inserted into intracorporal with flat thin-film covering 13 and highly sensitive receiving transducer array 14
Esophagus, and the high-power transmitting probe 11 of pipe end of probe and entrant sound flow container 15, mechanical control unit 16, signal processing unit
17 and communication unit 18, it is all in vitro.The operation keyboard or hand-held equipment of background process equipment issue control command,
Mechanical control unit is transmitted to by communication unit, mechanical control unit controls soft pipe and protrudes into suitable position, starts to work.First beat
The switch valve 19 of entrant sound flow container is opened, the entrant sound liquid inside entrant sound flow container injects soft pipe, reaches thin-film covering, film along soft pipe
Set becomes larger, and is finally full of soft pipe and thin-film covering.Highly sensitive receiving transducer array and detection position Global-Coupling at thin-film covering.
External high-power transmitting probe emits ultrasound, and the entrant sound liquid in soft pipe and thin-film covering reaches detection position, reflection
Ultrasonic wave is transferred to signal processing unit by Thin cable line by highly sensitive receiving transducer array received, received detection data, then
Background process equipment processing display is transferred to by communication unit and is supplied to diagnosis.After detection is completed, with one
Absorption plant is sucked out entrant sound liquid out of thin-film covering and soft pipe, and thin-film covering is deflated to become smaller, then with thin-film covering and highly sensitive
The soft pipe of receiving transducer array takes out.
As shown in fig. 6, being a kind of course of work of intraductal ultrasonography detection device detection pattern described in the present embodiment.Some portion
The one-time detection process of position are as follows:
(1) soft pipe is inserted into the organs such as intracorporal tracheae or esophagus with thin-film covering and highly sensitive receiving transducer array,
Thin-film covering is flat at this time；
(2) entrant sound liquid is injected.Entrant sound liquid inside entrant sound flow container is injected soft pipe by the external port of soft pipe, and
Thin-film covering is reached along soft pipe, so that thin-film covering expansion becomes larger, last entrant sound liquid is full of soft pipe and thin-film covering；
(3) external acoustically-driven.Background process equipment determines the transmission power of ultrasound detection signal, is sent to by communication unit
Signal processing unit；Signal processing unit carries out digital-to-analogue turn by the signal that send that communication unit transmits to background process equipment
It changes with after corresponding power amplification, ultrasonic wave transmission is carried out by high-power transmitting probe, ultrasonic wave passes through soft pipe and thin-film covering
Interior entrant sound liquid reaches film jacket wall, is close to due to thin-film covering using acoustic window material and after expanding with detection position, couples, because
This ultrasonic wave easily propagates through film jacket wall and reaches detection position；
(4) reflecting ultrasonic wave for detection position is received.Ultrasonic wave reaches detection position, after testing position lower-hierarchy
Reflection forms back wave, and each receiving transducer of the highly sensitive receiving transducer array in thin-film covering receives a back wave,
It is converted into electric signal, signal processing unit is reached by thin wire.Multiple receiving transducers receive signal processing unit by multiple
Reflection wave groups at one group of signal, signal processing unit amplification preposition to this group of signal, analog-to-digital conversion and caching, later again by leading to
Letter unit is transmitted to background process equipment.
(5) processing of background process equipment and imaging display.The data that background process equipment receives be multiple spatial positions not
Multiple back waves of same receiving transducer acquisition, and due to the highly sensitive receiving transducer battle array in background process equipment known film set
The position of each receiving transducer is arranged, therefore obtains the three-dimensional imaging that this position is this time detected after being handled.
It is to be set by controlling background process furthermore it is also possible to carry out the detection of different directions to the same detection position
Standby operation keyboard or hand-held equipment, and then this control command is transmitted to mechanical control unit by communication unit, by machinery
The intracorporal soft pipe rotation of control unit control insertion, and then thin-film covering and highly sensitive receiving transducer array rotation are driven, then weigh
Multiple (3) (4) (5).The three-dimensional imaging of different directions can be spliced into relatively sharp rotatable three by known location
Tie up three-dimensional imaging.The detection at next position is carried out, then passes through the operation keyboard or hand-held equipment of background process equipment
Control, moves up and down the position of soft pipe, reaches next detection position, repeat (3) (4) (5).
As shown in fig. 7, being a kind of course of work of intraductal ultrasonography detection device treatment mode described in the present embodiment.When certain
Position can enable this mode when needing to carry out ultrasonic therapy.This mode needs to increase the transmission power of ultrasonic signal, so that greatly
The ultrasonic wave of power emission probe transmitting passes through the entrant sound liquid in soft pipe and thin-film covering and reaches detection position, and then carries out ultrasound
Treatment.When having phlegm such as esophagus, transmission power can be increased to achieve the purpose that ultrasonic resolving sputum.
Its course of work can are as follows: detects that some position has exception directly to increase ultrasound when needing to treat in detection pattern
The transmission power of signal to carry out ultrasonic therapy to the position.It is also possible to enable detection pattern not yet, directly arrives treatment mould
Formula, then process are as follows:
(1) soft pipe is inserted into the organs such as intracorporal tracheae or esophagus with thin-film covering and highly sensitive receiving transducer array；
(2) entrant sound liquid is injected.Entrant sound liquid inside entrant sound flow container is injected soft pipe by the external port of soft pipe, and
Thin-film covering is reached along soft pipe, so that thin-film covering expansion becomes larger, last entrant sound liquid is full of soft pipe and thin-film covering；
(3) external acoustically-driven.Background process equipment determines ultrasonic therapy signal transmission power, is sent to letter by communication unit
Number processing unit；Signal processing unit carries out digital-to-analogue conversion by the signal that send that communication unit transmits to background process equipment
After corresponding power amplification, ultrasonic wave transmission is carried out by high-power transmitting probe；
(4) internal ultrasonic therapy.The ultrasonic wave of high-power transmitting probe transmitting passes through the entrant sound in soft pipe and thin-film covering
Liquid reaches therapentic part, carries out ultrasonic therapy；
The treatment of different directions can be carried out to the same therapentic part after the completion of the seance process at some position,
It is the operation keyboard or hand-held equipment by controlling background process equipment, and then this control command is passed by communication unit
It to mechanical control unit, is rotated by the intracorporal soft pipe of mechanical control unit control insertion, and then drives thin-film covering and highly sensitive
Receiving transducer array rotation repeats (3) (4).The treatment at next position is carried out, then passes through background process equipment
Keyboard or the control of hand-held equipment are operated, the position of soft pipe is moved up and down, reaches next therapentic part, repeat (3) (4)
?.
As shown in figure 8, being a kind of course of work of intraductal ultrasonography detection method described in the present embodiment.
(1) parameter setting.Set the signal to be sent in background process equipment end, transmission power selection, model selection,
Display parameters.The signal to be sent can use the ultrasound detection of different frequency bands according to detection or therapentic part difference or surpass
Sound treats signal；Transmission power selection, and different transmission powers is selected according to detection or therapentic part difference；Mode choosing
It has selected detection pattern and two kinds for the treatment of mode optional；The parameter that display parameters are then mainly imaged.
(2) soft pipe is inserted into the organs such as intracorporal tracheae or esophagus with thin-film covering and highly sensitive receiving transducer array；
(3) entrant sound liquid is injected.Entrant sound liquid inside entrant sound flow container is injected soft pipe by the external port of soft pipe, and
Thin-film covering is reached along soft pipe, so that thin-film covering expansion becomes larger, last entrant sound liquid is full of soft pipe and thin-film covering；
If selecting detection pattern:
(4) external acoustically-driven.Background process equipment determines the transmission power of ultrasound detection signal, is sent to by communication unit
Signal processing unit；Signal processing unit carries out digital-to-analogue turn by the signal that send that communication unit transmits to background process equipment
It changes with after corresponding power amplification, ultrasonic wave transmission is carried out by high-power transmitting probe, ultrasonic wave passes through soft pipe and thin-film covering
Interior entrant sound liquid reaches film jacket wall, is close to due to thin-film covering using acoustic window material and after expanding with detection position, couples, because
This ultrasonic wave easily passes through film jacket wall and reaches detection position；
(5) reflecting ultrasonic wave for detection position is received.Ultrasonic wave reaches detection position, after testing position lower-hierarchy
Reflection forms back wave, and each receiving transducer of the highly sensitive receiving transducer array in thin-film covering receives a back wave,
It is converted into electric signal, signal processing unit is reached by thin wire.Multiple receiving transducers receive signal processing unit by multiple
Reflection wave groups at one group of signal, signal processing unit amplification preposition to this group of signal, analog-to-digital conversion and caching, later again by leading to
Letter unit is transmitted to background process equipment；
(6) processing of background process equipment and imaging display.The data that background process equipment receives be multiple spatial positions not
Multiple back waves of same receiving transducer acquisition, and due to the highly sensitive receiving transducer battle array in background process equipment known film set
The position of each receiving transducer is arranged, therefore obtains the three-dimensional imaging that this position is this time detected after being handled；
(7) rotation detection.By controlling the operation keyboard or hand-held equipment of background process equipment, and then this is controlled
Order is transmitted to mechanical control unit by communication unit, is rotated by the intracorporal soft pipe of mechanical control unit control insertion, and then band
Dynamic thin-film covering and the certain direction (or angle) of highly sensitive receiving transducer array rotation, then this detection position is detected.Weight
Multiple step (4) (5) (6) (7), until all-directional rotation is completed.Background process equipment obtains the omnidirectional detection data in this position,
More careful rotatable ultrasonic three-dimensional three-dimensional imaging and analysis is obtained with this；
(8) detection at next position.By controlling the operation keyboard or hand-held equipment of background process equipment, in turn
This control command is transmitted to mechanical control unit by communication unit, is moved by the intracorporal soft pipe of mechanical control unit control insertion
It is dynamic, and then thin-film covering and highly sensitive receiving transducer array is driven to be moved to next position, this detection position is detected.Weight
Multiple step (4) (5) (6) (7) (8), until all sites detection is completed；
If selecting treatment mode:
(4) external acoustically-driven.Background process equipment determines ultrasonic therapy signal transmission power, is sent to letter by communication unit
Number processing unit；Signal processing unit carries out digital-to-analogue conversion by the signal that send that communication unit transmits to background process equipment
After corresponding power amplification, ultrasonic wave transmission is carried out by high-power transmitting probe；
(5) internal ultrasonic therapy.The ultrasonic wave of high-power transmitting probe transmitting passes through the entrant sound in soft pipe and thin-film covering
Liquid reaches therapentic part, carries out ultrasonic therapy；
(6) rotation therapy.By controlling the operation keyboard or hand-held equipment of background process equipment, and then this is controlled
Order is transmitted to mechanical control unit by communication unit, is rotated by the intracorporal soft pipe of mechanical control unit control insertion, and then band
Dynamic thin-film covering and the certain direction (or angle) of highly sensitive receiving transducer array rotation, then this therapentic part is treated.Weight
Multiple step (4) (5) (6), until all-directional rotation is completed；
(7) treatment at next position.By controlling the operation keyboard or hand-held equipment of background process equipment, in turn
This control command is transmitted to mechanical control unit by communication unit, is moved by the intracorporal soft pipe of mechanical control unit control insertion
It is dynamic, and then thin-film covering and highly sensitive receiving transducer array is driven to be moved to next position, this therapentic part is treated.Weight
Multiple step (4) (5) (6) (7), until all sites treatment is completed；
Detection pattern and treatment mode can at work directly alternately, without taking out soft pipe.If in detection mould
In formula discovery need to treat, then operator is switched to treatment mode, increase ultrasonic signal transmission power come to the position into
Row ultrasonic therapy.If discovery needs to detect in treatment mode, operator is switched to detection pattern, reduces ultrasonic signal
Transmission power to carry out ultrasound detection to the position.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention,
It should be equivalent substitute mode, be included in protection scope of the present invention.
Claims (10)
1. a kind of intraductal ultrasonography detection and therapeutic device, it is characterised in that including pipe end of probe and by host, operation keyboard or hand
Hold the background process equipment of operation equipment and its display composition；Pipe end of probe includes high-power transmitting probe, entrant sound flow container, soft
Matter pipe, thin-film covering, highly sensitive receiving transducer array, mechanical control unit, signal processing unit and communication unit, end of probe pass through
Communication unit is communicated with background process equipment；The head end of the soft pipe is connected with high-power transmitting probe, and other end is end
End cap has thin-film covering, is provided with the external port being connected with entrant sound flow container near the head end of soft pipe, and entrant sound flow container is logical when work
It crosses external port and injects entrant sound liquid to soft pipe；The highly sensitive receiving transducer array is attached on thin-film covering inner wall；The machinery
Control unit control is inserted into intracorporal soft pipe, thin-film covering, highly sensitive receiving transducer array and is moved together, and movement includes insertion,
Up and down and rotation；The signal processing unit be mainly responsible for the signal that background process equipment transmits is cached, digital-to-analogue
Conversion, power control and power amplification, to the signal of highly sensitive receiving transducer array received carry out preposition amplification, analog-to-digital conversion and
Caching.
2. a kind of intraductal ultrasonography detection according to claim 1 and therapeutic device, it is characterised in that the communication unit is negative
Blame the wireless communication or wire communication between pipe end of probe and background process equipment.
3. a kind of intraductal ultrasonography detection according to claim 1 and therapeutic device, it is characterised in that the highly sensitive reception
Linear transducer array is the array of receiving transducer composition.
4. a kind of intraductal ultrasonography detection according to claim 3 and therapeutic device, it is characterised in that thin-film covering is using uniform
Thickness when, uniformly place receiving transducer inside entire thin-film covering.
5. a kind of intraductal ultrasonography detection according to claim 3 and therapeutic device, it is characterised in that thin-film covering is using non-equal
Even thickness places receiving transducer in thin place, and receiving transducer is that capacitance type micromachined ultrasonic is popped one's head in or film-type is popped one's head in.
6. a kind of intraductal ultrasonography detection according to claim 3 and therapeutic device, it is characterised in that soft tube wall applies non-
Acoustic window material, so that ultrasound is only propagated inside soft pipe；Entrant sound liquid is kept in inside the entrant sound flow container；The thin-film covering uses
Acoustic window material production.
7. intraductal ultrasonography detection and therapeutic device according to claim 1, it is characterised in that the high-power transmitting probe
For powerful piezoelectric ceramic transducer, ultrasonic wave is sent.
8. intraductal ultrasonography detection and therapeutic device according to claim 1, it is characterised in that entrant sound flow container passes through at work
Entrant sound liquid is injected towards soft pipe in the external port of soft pipe, and entrant sound liquid reaches thin-film covering along soft pipe, and thin-film covering expansion becomes larger,
The highly sensitive receiving transducer array and detection position that are arranged on thin-film covering inner wall are close to, highly sensitive receiving transducer array it is each
Receiving transducer is in the different position in space；When thin-film covering uniform thickness, thin-film covering can be global with detection position in large area
Coupling；When thin-film covering non-uniform thickness, then thin-film covering is expanded into irregular shape, thin place protrusion, thin-film covering and inspection
It is locally coupled to survey position.
9. intraductal ultrasonography detection and therapeutic device according to claim 1, it is characterised in that the highly sensitive receiving transducer
Cable between the receiving transducer and signal processing unit of array is thin wire, along the inner tubal wall and thin-film covering of soft pipe
Wall arrangement, when work soft pipe and thin-film covering be filled with entrant sound liquid, entrant sound liquid be the material to insulate.
10. any one intraductal ultrasonography detection and therapeutic device according to claim 1 ~ 9, it is characterised in that the pipe detection
Entrant sound flow container, mechanical control unit, signal processing unit, communication unit and the high-power transmitting probe at end are located at external, machinery
Control unit, signal processing unit, communication unit and high-power transmitting probe are integrated on one piece of plank；The end of soft pipe,
Thin-film covering and highly sensitive receiving transducer array are inserted into intracorporal tracheae or esophagus when working.
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Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5078144A (en) * | 1988-08-19 | 1992-01-07 | Olympus Optical Co. Ltd. | System for applying ultrasonic waves and a treatment instrument to a body part |
| DE19932261A1 (en) * | 1999-07-07 | 2001-01-11 | Univ Schiller Jena | Device for transbronchial and transtracheal endosonography has conventional tube with circular cuff near distal end and channel for accommodating ultrasonic catheter on tube wall |
| CN201015682Y (en) * | 2007-02-12 | 2008-02-06 | 重庆海扶(Hifu)技术有限公司 | Headgear for ultrasonic therapy |
| CN201790835U (en) * | 2010-09-19 | 2011-04-13 | 中国人民解放军第三军医大学第三附属医院 | Endoscope lens with water sac |
| CN103385694A (en) * | 2012-05-11 | 2013-11-13 | 三星电子株式会社 | Optical coherence tomography apparatus for diagnosing breast cancer and method of controlling same |
| CN204394572U (en) * | 2014-12-30 | 2015-06-17 | 上海派拉纶生物技术有限公司 | A kind of penetration type Ultrasonic-B probe |
| CN204698605U (en) * | 2015-06-11 | 2015-10-14 | 青岛市第八人民医院 | A kind of rotary type multifunctional vaginal Ultrasonic-B probe |
| CN204950995U (en) * | 2015-03-17 | 2016-01-13 | 广东省人民医院 | Area cover bag is through esophagus ultrasonic probe |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3954888B2 (en) * | 2002-04-11 | 2007-08-08 | テルモ株式会社 | Ultrasound catheter |
| JP6129509B2 (en) * | 2012-10-04 | 2017-05-17 | 東芝メディカルシステムズ株式会社 | Ultrasonic medical apparatus and ultrasonic diagnostic imaging apparatus |
-
2016
- 2016-05-26 CN CN201610365299.XA patent/CN106073828B/en not_active Expired - Fee Related
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5078144A (en) * | 1988-08-19 | 1992-01-07 | Olympus Optical Co. Ltd. | System for applying ultrasonic waves and a treatment instrument to a body part |
| DE19932261A1 (en) * | 1999-07-07 | 2001-01-11 | Univ Schiller Jena | Device for transbronchial and transtracheal endosonography has conventional tube with circular cuff near distal end and channel for accommodating ultrasonic catheter on tube wall |
| CN201015682Y (en) * | 2007-02-12 | 2008-02-06 | 重庆海扶(Hifu)技术有限公司 | Headgear for ultrasonic therapy |
| CN201790835U (en) * | 2010-09-19 | 2011-04-13 | 中国人民解放军第三军医大学第三附属医院 | Endoscope lens with water sac |
| CN103385694A (en) * | 2012-05-11 | 2013-11-13 | 三星电子株式会社 | Optical coherence tomography apparatus for diagnosing breast cancer and method of controlling same |
| CN204394572U (en) * | 2014-12-30 | 2015-06-17 | 上海派拉纶生物技术有限公司 | A kind of penetration type Ultrasonic-B probe |
| CN204950995U (en) * | 2015-03-17 | 2016-01-13 | 广东省人民医院 | Area cover bag is through esophagus ultrasonic probe |
| CN204698605U (en) * | 2015-06-11 | 2015-10-14 | 青岛市第八人民医院 | A kind of rotary type multifunctional vaginal Ultrasonic-B probe |
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