CN105997303A - 3DP customized bionic lenses as well as preparation method and device thereof - Google Patents
3DP customized bionic lenses as well as preparation method and device thereof Download PDFInfo
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- CN105997303A CN105997303A CN201610309594.3A CN201610309594A CN105997303A CN 105997303 A CN105997303 A CN 105997303A CN 201610309594 A CN201610309594 A CN 201610309594A CN 105997303 A CN105997303 A CN 105997303A
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- eyeglass
- bionical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y10/00—Processes of additive manufacturing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y50/00—Data acquisition or data processing for additive manufacturing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Manufacturing & Machinery (AREA)
- Materials Engineering (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The invention in particular relates to 3DP customized bionic lenses as well as a preparation method and a preparation device of the 3DP customized bionic lenses. The preparation method comprises the following steps: acquiring morphological parameters of eyeballs of a wearer, wherein the morphological parameters of eyeballs comprise cornea diameter, curvature radius, refraction state, microcoria skiascopy parameter and mydriasis skiascopy parameter; calculating three-dimensional model data of the bionic lenses to be prepared according to the morphological parameters of the eyeballs; controlling a 3D printer to print a three-dimensional model of the bionic lenses to be prepared according to the three-dimensional model data; placing the three-dimensional model into a cold trap for freezing formation, thus obtaining the formed bionic lenses; and sequentially carrying out polishing, grinding and deburring treatment on the formed bionic lenses. According to the technical scheme provided by the invention, the manufacturing process of the implantable collamer lenses is simplified, the cost of the implantable collamer lenses is reduced, and the range of choice of a user for wearing the implantable contact lenses is widened.
Description
Technical field
The present invention relates to bionical eyeglass manufacture technology field, be specifically related to a kind of 3DP customize bionical eyeglass and
Its manufacture method and device.
Background technology
Implantable contact lens (ICL, Implantable Collamer Lens), it is current safety, height
The myoporthosis scheme of end.Operation from laser and other cutting corneal tissue is different, its not cutting angle
Film, by Minimally Invasive Surgery by Lens implantation ophthalmic, corneal not damaged.After rectification, vision is apparent,
Being the new trend of near-sightedness correction technology, existing more than 60 country in the whole world carries out this correcting technology, every 6 points
Clock just has 1 piece of ICL to implant.
In China, in high myopia, especially high myopia (>=800 degree) patient, many people are because of angle
Film thickness is inadequate or relatively thin, and can not carry out excimer laser rectification, and ICL is to high myopia
Patient brings new hope.Briefly, it is simply that " being designed to the ultra-thin eyeglass of myopia correction " is positioned over
Back room gap in eye refraction system, and be fixed in ciliary groove, reach permanent correction of refractive errors
Purpose.ICL can permanently insert ophthalmic.But, rectify or owe to rectify if it occur that cross, or occur
Complication, or when the vision of patient changes, can be by the ophthalmic surgeon through training by ICL
Take out or be replaced.ICL be presently believed to be alternative LASIK, PRK and other cutting perform the operation into
The state-of-the-art technology of row correction of refractive errors, is one of the up-to-date and safest technology of correction of myopia.
ICL artificial intraocular lenses is the proprietary material that a kind of refrangibility intraocular surgery is used: Collamer, is
A kind of FA crystalline material, beThe most special material of Surgical company, should
For various photorefractive crystals.The raw material of ICL artificial intraocular lenses is that the collagen that STAAR company exclusively produces is many
Polymers (Collamer), it is polymerized by collagen purification, has good biocompatibility, within the eye
Without any untoward reaction, meet structoure of the human body.But owing to ICL artificial intraocular lenses's requirement eye is customized, then
From Switzerland's import, so price is relatively costly.
Summary of the invention
In view of this, it is an object of the invention to overcome the deficiencies in the prior art, it is provided that a kind of 3DP customization
Bionical eyeglass and preparation method thereof and device, reduce the cost of implantable contact lens in prior art.
For realizing object above, the present invention adopts the following technical scheme that
A kind of 3DP customizes bionical eyeglass manufacture method, including:
Step S1, the eyeball shape parameter of acquisition wearer, wherein, described eyeball shape parameter bag
Include corneal diameter, radius of curvature, refractive status, microcoria inspection shadow parameter and mydriasis inspection shadow parameter；
Step S2, according to described eyeball shape parameter, calculate the threedimensional model of bionical eyeglass to be prepared
Data；
Step S3, according to described three-dimensional modeling data, control 3D printer and print bionical mirror to be prepared
The threedimensional model of sheet；
Step S4, being put into by described threedimensional model and carry out freeze forming in cold-trap, obtain after molding is bionical
Eyeglass；
Step S5, to the bionical eyeglass after molding, be polished successively, polish and flash removed process.
Preferably, after described step S5, also include:
By through polishing, polishing and flash removed process bionical eyeglass be put into circulation dish carry out surface quality and
Focal power check, and will check after eyeglass put into packaging container is carried out seal sterilizing.
Preferably, described eyeball shape parameter also includes: use the angle that slit lamp microscope observation obtains
Film, anterior chamber measurement；Use the eye anterior chamber angle parameter that corneal topography inspection obtains；Use cornea is bent
Corneal thickness that rate meter obtains, corneal endothelial cell counting, pupil diameter；Eye PET/CT is used to carry out three-dimensional
Tomoscan, the eye three-dimensional parameter obtained.
Preferably, the printed material that 3D printer printing bionical eyeglass to be prepared is used includes poly
HEMA hydrogel, water and pig collagen, wherein, the quality accounting of poly HEMA hydrogel is 63%,
The quality accounting of water is 33% and the quality accounting of pig collagen is 0.2%.
A kind of 3DP customizes bionical eyeglass producing device, including:
Acquiring unit, for obtaining the eyeball shape parameter of wearer, wherein, described eyeball shape
Parameter includes corneal diameter, radius of curvature, refractive status, microcoria inspection shadow parameter and mydriasis inspection shadow parameter；
Computing unit, for according to described eyeball shape parameter, calculates the three of bionical eyeglass to be prepared
Dimension module data；
Control unit, for according to described three-dimensional modeling data, controls 3D printer and prints to be prepared imitating
The threedimensional model of raw eyeglass；
Freeze forming unit, carries out freeze forming for being put into by described threedimensional model, is become in cold-trap
Bionical eyeglass after type；
Processing unit, for the bionical eyeglass after molding, is polished successively, polishes and at flash removed
Reason.
Preferably, described implanted contact lens producing device, also include:
Encapsulation unit, for being put into circulation dish by the bionical eyeglass processed through polishing, polishing and flash removed
Carry out surface quality and focal power inspection, and the eyeglass after checking is put into and carried out in packaging container sealing sterilizing.
A kind of 3DP customizes bionical eyeglass, and described contact lens customizes bionical eyeglass system according to above-mentioned 3DP
Make method preparation, and implanted the ophthalmic of wearer by ICL operation.
The present invention uses above technical scheme, at least possesses following beneficial effect:
This 3DP that the present invention provides customizes bionical eyeglass and preparation method thereof and device, according to wearer
Eyeball shape parameter, calculate the three-dimensional modeling data of bionical eyeglass to be prepared and control 3D printer
Print the threedimensional model of bionical eyeglass to be prepared, then described threedimensional model is carried out freeze forming, throwing
Light, polishing and flash removed process, and compared to existing technology, simplify the making stream of implantable contact lens
Journey, reduces the cost of implantable contact lens, adds user and wears implantable contact lens
The range of choice.
It is understood that the eyeball shape parameter of each wearer varies, due to this
This 3DP that invention provides customizes bionical eyeglass and preparation method thereof and device is real based on 3D printer
Existing, different three-dimensional modeling datas, 3D can be calculated according to the eyeball shape parameter of different wearers
Printer carries out eyeglass according to these three-dimensional modeling datas and prints, and therefore can ensure low cost
Under premise, meet customization the sexual needs of various user.
Accompanying drawing explanation
The flow process that Fig. 1 customizes bionical eyeglass manufacture method for a kind of 3DP that one embodiment of the invention provides is shown
It is intended to；
Fig. 2 customizes the schematic block of bionical eyeglass producing device for a kind of 3DP that one embodiment of the invention provides
Figure.
Detailed description of the invention
Below by drawings and Examples, technical scheme is described in further detail.Ginseng
Seeing Fig. 1, a kind of 3DP that one embodiment of the invention provides customizes bionical eyeglass manufacture method, including:
Step S1, the eyeball shape parameter of acquisition wearer, wherein, described eyeball shape parameter bag
Include corneal diameter, radius of curvature, refractive status, microcoria inspection shadow parameter and mydriasis inspection shadow parameter；
Step S2, according to described eyeball shape parameter, calculate the threedimensional model of bionical eyeglass to be prepared
Data；
Step S3, according to described three-dimensional modeling data, control 3D printer and print bionical mirror to be prepared
The threedimensional model of sheet；
Step S4, being put into by described threedimensional model and carry out freeze forming in cold-trap, obtain after molding is bionical
Eyeglass；
Step S5, to the bionical eyeglass after molding, be polished successively, polish and flash removed process.
As shown from the above technical solution, this 3DP that the present invention provides customizes bionical eyeglass manufacture method,
Eyeball shape parameter according to wearer, calculates the three-dimensional modeling data of bionical eyeglass to be prepared and controls
3D printer processed prints the threedimensional model of bionical eyeglass to be prepared, then carries out cold to described threedimensional model
Be frozen into type, polish, polish and flash removed process, compared to existing technology, simplify implantable stealth eye
The Making programme of mirror, reduces the cost of implantable contact lens, adds user and wears implantable
The range of choice of contact lens.
It is understood that the eyeball shape parameter of each wearer varies, due to this
This 3DP that invention provides customizes bionical eyeglass manufacture method and realizes based on 3D printer, can root
Calculate different three-dimensional modeling datas according to the eyeball shape parameter of different wearers, 3D printer according to
These three-dimensional modeling datas carry out eyeglass and print, therefore can be full on the premise of ensureing low cost
Foot various users customization sexual needs (such as: myopia degree, astigmatism degree, the radian of eyeglass,
Hardness, toughness, wettability, transmittance etc.).
Preferably, after described step S5, also include:
By through polishing, polishing and flash removed process bionical eyeglass be put into circulation dish carry out surface quality and
Focal power check, and will check after eyeglass put into packaging container is carried out seal sterilizing.
It is understood that bionical eyeglass is packaged sterilizing, eyeglass is made to be in gnotobasis, can
Prevent eyeglass from occurring during transport and use rotten, it is ensured that the safe wearing of implantable contact lens.
Preferably, described eyeball shape parameter also includes: use the angle that slit lamp microscope observation obtains
Film, anterior chamber measurement；Use the eye anterior chamber angle parameter that corneal topography inspection obtains；Use cornea is bent
Corneal thickness that rate meter obtains, corneal endothelial cell counting, pupil diameter；Eye PET/CT is used to carry out three-dimensional
Tomoscan, the eye three-dimensional parameter obtained.
Preferably, the printed material that 3D printer printing bionical eyeglass to be prepared is used includes poly
HEMA hydrogel, water and pig collagen, wherein, the quality accounting of poly HEMA hydrogel is 63%,
The quality accounting of water is 33% and the quality accounting of pig collagen is 0.2%.
It addition, see Fig. 2, present invention also offers a kind of 3DP and customize bionical eyeglass producing device 100,
Including:
Acquiring unit 101, for obtaining the eyeball shape parameter of wearer, wherein, described eyeball shape
Learn parameter and include corneal diameter, radius of curvature, refractive status, microcoria inspection shadow parameter and mydriasis inspection shadow ginseng
Number；
Computing unit 102, for according to described eyeball shape parameter, calculates bionical eyeglass to be prepared
Three-dimensional modeling data；
Control unit 103, for according to described three-dimensional modeling data, controls 3D printer and prints to be prepared
The threedimensional model of bionical eyeglass；
Freeze forming unit 104, carries out freeze forming for being put into by described threedimensional model, obtains in cold-trap
Bionical eyeglass after molding；
Processing unit 105, for the bionical eyeglass after molding, is polished successively, polishes and flash removed
Process.
Preferably, described implanted contact lens producing device 100, also include:
Encapsulation unit 106, for being put into circulation by the bionical eyeglass processed through polishing, polishing and flash removed
Dish carries out surface quality and focal power inspection, and the eyeglass after checking is put into and carried out sealing in packaging container and go out
Bacterium.
It addition, the present embodiment additionally provides a kind of 3DP customizes bionical eyeglass, described 3DP customizes bionical mirror
Sheet customizes the preparation of bionical eyeglass manufacture method according to above-mentioned 3DP, and implants wearer by ICL operation
Ophthalmic.
It should be noted that before carrying out ICL operation, wearer needs to check as follows:
1, intraocular pressure: high intraocular pressure is easily caused too much aqueous humor and is trapped in ophthalmic eyewall is formed pressure, thus leads
Cause the ophthalmic diseasess such as glaucoma, so it is necessary for surveying intraocular pressure.
2, cornea and corneal curvature inspection: can effectively check the transparency of cornea and dissipating of eyes
Light state, significant to operation selection and postoperative judgement.
3, anterior chamber and angle of anterior chamber inspection: aqueous flare positive prompting iridocyclitis, preoperative should fit
Work as treatment.The trouble eye that angle of anterior chamber is narrow, can the excision of combined with peripheral iris in art.
4, vision: check respectively near vision and distance vision two kinds, this is definitely that ICL is preoperative to closing weight
The inspection wanted, only determines the situation of vision, could customize suitable ICL crystal, thus be patient
Obtain optimal correcting defects of vision.
5, the visual field: the most simultaneous glaucoma or other oculopathy should be made perimetry.
6, posterior segment inspection: check understand as far as possible under mydriasis vitreous body, retina, regarding nipple, macula lutea
District is the most normal and choroid is with or without pathological changes, can understand with or without disease of vitreous by A type and B ultrasound
Become, detachment of retina or ophthalmic swell thing.Electroretinogram has important value to evaluating retinal function.
7, the mensuration of the bionical eyeglass number of degrees: surpass the axiallength of mensuration and with crooking rate of cornea meter or angle according to A
The corneal refractive power that film topography is measured, application SRK II formula calculates the number of degrees of bionical eyeglass.
8, iris and pupil examination: iris has new vessels person, can use coagulation when excising iris in art
The iris scissors of effect.Check reaction of pupil to light and platycoria ability, if having adhesion, contribute to system
Determine operation plan.
The present invention is not limited to above-mentioned preferred forms, and anyone can draw under the enlightenment of the present invention
Other various forms of products, no matter but in its shape or structure, make any change, every have and this
Apply for same or like as technical scheme, within all falling within protection scope of the present invention.
Claims (7)
1. a 3DP customizes bionical eyeglass manufacture method, it is characterised in that including:
Step S1, the eyeball shape parameter of acquisition wearer, wherein, described eyeball shape parameter bag
Include corneal diameter, radius of curvature, refractive status, microcoria inspection shadow parameter and mydriasis inspection shadow parameter；
Step S2, according to described eyeball shape parameter, calculate the threedimensional model of bionical eyeglass to be prepared
Data；
Step S3, according to described three-dimensional modeling data, control 3D printer and print bionical mirror to be prepared
The threedimensional model of sheet；
Step S4, being put into by described threedimensional model and carry out freeze forming in cold-trap, obtain after molding is bionical
Eyeglass；
Step S5, to the bionical eyeglass after molding, be polished successively, polish and flash removed process.
3DP the most according to claim 1 customizes bionical eyeglass manufacture method, it is characterised in that
After described step S5, also include:
By through polishing, polishing and flash removed process bionical eyeglass be put into circulation dish carry out surface quality and
Focal power check, and will check after eyeglass put into packaging container is carried out seal sterilizing.
3DP the most according to claim 1 customizes bionical eyeglass manufacture method, it is characterised in that institute
State eyeball shape parameter also to include: the cornea, the anterior chamber shape that use slit lamp microscope observation to obtain are joined
Number；Use the eye anterior chamber angle parameter that corneal topography inspection obtains；Use the cornea that keratometer obtains
Thickness, corneal endothelial cell counting, pupil diameter；Use eye PET/CT to carry out three-dimensional tomographic, obtain
Eye three-dimensional parameter.
4. customize bionical eyeglass manufacture method, its feature according to the 3DP described in any one of claims 1 to 3
Being, the printed material that 3D printer printing bionical eyeglass to be prepared is used includes poly HEMA
Hydrogel, water and pig collagen, wherein, the quality accounting of poly HEMA hydrogel is 63%, the matter of water
Amount accounting is 33% and the quality accounting of pig collagen is 0.2%.
5. a 3DP customizes bionical eyeglass producing device, it is characterised in that including:
Acquiring unit, for obtaining the eyeball shape parameter of wearer, wherein, described eyeball shape
Parameter includes corneal diameter, radius of curvature, refractive status, microcoria inspection shadow parameter and mydriasis inspection shadow parameter；
Computing unit, for according to described eyeball shape parameter, calculates the three of bionical eyeglass to be prepared
Dimension module data；
Control unit, for according to described three-dimensional modeling data, controls 3D printer and prints to be prepared imitating
The threedimensional model of raw eyeglass；
Freeze forming unit, carries out freeze forming for being put into by described threedimensional model, is become in cold-trap
Bionical eyeglass after type；
Processing unit, for the bionical eyeglass after molding, is polished successively, polishes and at flash removed
Reason.
3DP the most according to claim 5 customizes bionical eyeglass producing device, it is characterised in that also
Including:
Encapsulation unit, for being put into circulation dish by the bionical eyeglass processed through polishing, polishing and flash removed
Carry out surface quality and focal power inspection, and the eyeglass after checking is put into and carried out in packaging container sealing sterilizing.
7. a 3DP customizes bionical eyeglass, it is characterised in that described 3DP customize bionical eyeglass according to
3DP described in any one of Claims 1 to 4 customizes the preparation of bionical eyeglass manufacture method, and by ICL hands
Art implants the ophthalmic of wearer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201610309594.3A CN105997303A (en) | 2016-05-11 | 2016-05-11 | 3DP customized bionic lenses as well as preparation method and device thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201610309594.3A CN105997303A (en) | 2016-05-11 | 2016-05-11 | 3DP customized bionic lenses as well as preparation method and device thereof |
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| CN201610309594.3A Pending CN105997303A (en) | 2016-05-11 | 2016-05-11 | 3DP customized bionic lenses as well as preparation method and device thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106901873A (en) * | 2017-03-09 | 2017-06-30 | 首都医科大学附属北京同仁医院 | The preparation method of intraocular lens |
| CN110039806A (en) * | 2019-04-23 | 2019-07-23 | 首都医科大学附属北京同仁医院 | A kind of high-accuracy 3D printing method of personalized eye eyeglass |
| CN113001986A (en) * | 2021-03-23 | 2021-06-22 | 上海红阵信息科技有限公司 | Method for manufacturing 3D model based on bionic material |
| WO2021232972A1 (en) * | 2020-05-19 | 2021-11-25 | 微智医疗器械有限公司 | Method for manufacturing electrode array forming die, shaping method, clamping tool, and medium |
| CN114179361A (en) * | 2017-03-22 | 2022-03-15 | 爱尔康公司 | 3D printing of intraocular lenses with smooth curved surfaces |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106901873A (en) * | 2017-03-09 | 2017-06-30 | 首都医科大学附属北京同仁医院 | The preparation method of intraocular lens |
| CN114179361A (en) * | 2017-03-22 | 2022-03-15 | 爱尔康公司 | 3D printing of intraocular lenses with smooth curved surfaces |
| US11897190B2 (en) | 2017-03-22 | 2024-02-13 | Alcon Inc. | 3D printing of an intraocular lens having smooth, curved surfaces |
| CN110039806A (en) * | 2019-04-23 | 2019-07-23 | 首都医科大学附属北京同仁医院 | A kind of high-accuracy 3D printing method of personalized eye eyeglass |
| WO2021232972A1 (en) * | 2020-05-19 | 2021-11-25 | 微智医疗器械有限公司 | Method for manufacturing electrode array forming die, shaping method, clamping tool, and medium |
| CN113001986A (en) * | 2021-03-23 | 2021-06-22 | 上海红阵信息科技有限公司 | Method for manufacturing 3D model based on bionic material |
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