CN105943056A - Neonate pertacuneous jaundice tester and client - Google Patents
Neonate pertacuneous jaundice tester and client Download PDFInfo
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- CN105943056A CN105943056A CN201610334677.8A CN201610334677A CN105943056A CN 105943056 A CN105943056 A CN 105943056A CN 201610334677 A CN201610334677 A CN 201610334677A CN 105943056 A CN105943056 A CN 105943056A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/04—Babies, e.g. for SIDS detection
- A61B2503/045—Newborns, e.g. premature baby monitoring
Abstract
The invention provides a neonate pertacuneous jaundice tester comprising the following elements: a lighting module used for alternatively emitting a first light ray and a second light ray to a neonate according to a preset frequency under the control of a control module, wherein the first and second light rays contain the lights different from a preset wavelength and used for measuring the neonate bilirubin real concentration; a light acquisition module controlled by the control module so as to regularly collect first and second light rays emitted into and reflected from the neonate skin, and the collected light rays are converted to obtain corresponding a first signal and a second signal; a communication module used for outputting the first and second electric signals so as to allow the terminal, having the bilirubin concentration information, to real time monitor the neonate bilirubin concentration, thus making fast diagnosis reaction when the neonate bilirubin concentration is abnormal, reducing neonate sickening risks in the maximum level, and ensuring neonate health.
Description
Technical field
The invention belongs to measuring instrument technical field, particularly to a kind of neonatal percutaneous jaundice instrument
And client.
Background technology
Medically non-full moon (in being born 28 days) neonatal jaundice, referred to as neonate is yellow
Subcutaneous ulcer.Neonatal jaundice refers to non-neonate, owing to bilirubin metabolism is abnormal, causes in blood
Bilirubin concentration raises, and comes across the disease of skin, mucosa and yellow sclera, and primary disease has life
Rationality and pathologic point.Physiologic jaundice occurs after birth for 2～3 days, within 4～6 days, reaches high
Peak, disappears for 7～10 days, and premature infant's persistent period is longer, in addition to having slight inappetence, without it
His clinical symptoms.If within latter 24 hours, jaundice i.e. occur raw, every day, serum bilirubin increased to over
5mg/dl or per hour > 0.5mg/dl；Persistent period is long, term infant > 2 weeks, premature infant > 4 weeks still
Do not move back, even continue to repeat after intensification increases the weight of or disappears, or raw one week after is to ability in several weeks
Start that jaundice occurs, be pathological jaundice.Unconjugated bilirubin has certain toxicity, can pass through
Biomembrane and blood brain barrier.In blood, unconjugated bilirubin is too high, and central nervous system can be caused to be subject to
Damaging, produce bilirubin encephalopathy, concurrent bilirubin encephalopathy or brain tissue damage, serious threat neonate is raw
Life and health, mortality rate is the highest.
Skin icterus tester is that one is more effective and neonatal bilirubin undamaged to neonate
Concentration measuring instrument.The cardinal principle of Skin icterus tester is the suction utilizing skin mesobilirubin to light
Receive reflection, the reflected light signal after light source incidence skin is converted into bilirubin concentration.People
Body skin is typically made up of, wherein epidermal area, skin corium and three major parts of hypodermis layer
Bilirubin and hemoglobin are all present in the blood capillary of skin corium, light incidence skin, pass through
Specular scattering, understands some light diffuse-reflectance again from skin out, and this part light carries skin
The relevant information of interior material.Bilirubin is the most obvious to the optical absorption of 460nm wavelength, but
Also exist in the hemoglobin of skin corium the light of this wavelength be there is also partially absorb, in order to go
Except the interference of hemoglobin, the reflection light of reselection 550nm wavelength, the light of this wavelength is red to gallbladder
Plain is absorbed as 0, simultaneously equal, by this with at 460nm wavelength to the absorption value of hemoglobin
The reflection light gathered under two kinds of wavelength carries out difference, the impact of the most removable hemoglobin, obtains
Only the reflection light containing bilirubin information, demarcates reception light with standard bilirubin concentration afterwards,
Determine its linear relationship, obtain conversion formula, determine bilirubin concentration.
But existing hand-held Skin icterus tester have a problem in that existing hand-held warp
Beijing opera subcutaneous ulcer instrument is all that single reading is measured, it is impossible to realize monitoring in real time in 24 hours, for just birth
For one week this neonatal jaundice high-incidence season, it is difficult to determine that bilirubin concentration is different in the very first time
Often, it is impossible to quickly make diagnostic reaction.Additionally, the dual wavelength that existing Skin icterus tester uses
Method only accounts for the hemoglobin impact on measuring, but the melanin suction to light under 460nm wavelength
Receipts there is also certain share, say, that existing double-wavelength method cannot remove baby's colour of skin for
The interference measured.And existing hand-held Skin icterus tester build is big, portability is poor, surveys every time
Amount is both needed to manually participate in, inconvenient during repetitive measurement.Function is the most single simultaneously, it is impossible in inspection
Look into bilirubinic other physical signs to other babies simultaneously of baby.
Summary of the invention
It is an object of the present invention to provide a kind of neonatal percutaneous jaundice instrument, solve in prior art
At least one technical problem existed.
In order to achieve the above object, the invention provides a kind of neonatal percutaneous jaundice instrument and visitor
Family end.
First aspect, the invention provides a kind of neonatal percutaneous jaundice instrument, including: luminous mould
Block, light acquisition module, processing module, communication module and control module；
Wherein,
Described light emitting module, for pressing the frequency preset to neonate under the control of control module
Alternate emission the first light and the second light, wherein, described first light and the second light have
Different preset wavelengths, for measuring the light of neonatal bilirubin actual concentrations；
Described light acquisition module, injects new life for taken at regular intervals under the control of control module
The first light that youngster's skin is reflected out and the second light, and converted process obtains accordingly
First signal and secondary signal；
Described communication module, for exporting described first signal of telecommunication and second signal of telecommunication.
Preferably,
Described light emitting module, is additionally operable under the control of control module by default frequency to new life
Youngster's alternate emission the first light, the second light and the 3rd light, wherein, described 3rd light
It is different from described first light and the second light for wavelength, is used for eliminating newborn skin melanin
Light on the impact of bilirubin actual concentrations；
Described light acquisition module, is additionally operable to taken at regular intervals under the control of control module and injects newly
The first light, the second light and the 3rd light that raw youngster's skin is reflected out, and converted
Process obtains corresponding first signal of telecommunication, second signal of telecommunication and the 3rd signal of telecommunication；
Described communication module, for by described first signal of telecommunication, second signal of telecommunication and the 3rd electricity
Signal exports.
Preferably, described Skin icterus tester also includes temperature-measuring module and pulses measure module；
Described temperature-measuring module, is used for measuring neonatal body temperature and being converted to corresponding temperature
Information；
Described pulses measure module, is used for measuring neonatal pulse and being converted to corresponding pulse
Information；
Described communication module, is additionally operable to export described temperature information and pulse information.
Preferably, described light emitting module includes several LED light sources and several optical filters,
Each LED light source is the light of outgoing preset wavelength under corresponding optical filter coordinates.
Preferably, described communication module is bluetooth module.
Preferably, described control module is embedded microprocessor.
Second aspect, the invention provides a kind of client, including:
Acquiring unit, for obtaining the signal of telecommunication received by terminal, the described signal of telecommunication is such as power
Profit requires the signal of telecommunication of communication module output in the arbitrary described neonatal percutaneous jaundice instrument of 1-6；
Processing module, for obtaining bilirubin concentration information according to the described signal of telecommunication；
Judging unit, for when receiving bilirubin concentration information for the first time, works as if judging to know
Front bilirubin concentration information is the bilirubin concentration information measured in neonate is born one hour,
And this bilirubin concentration information more than first threshold time, then control described terminal send warning instruction；
Described judging unit, when being additionally operable to receive after the first bilirubin concentration information, if
Judge to know that current bilirubin concentration information more than Second Threshold, then controls described terminal and sends
Report to the police and indicate；If judging to know that current bilirubin concentration information is less than Second Threshold and adjacent
The interpolation of the bilirubin concentration information of twice reception is more than the 3rd threshold value, then control described terminal and send out
Go out instruction of reporting to the police.
Preferably, described acquiring unit, it is further used for obtaining the first electricity received by terminal
Signal and second signal of telecommunication；
Described processing module, is further used for carrying out described first signal of telecommunication and second signal of telecommunication
Difference, then method based on linear regression obtains bilirubin concentration information.
Preferably, described acquiring unit, it is further used for obtaining the first electricity received by terminal
Signal, second signal of telecommunication and the 3rd signal of telecommunication, described first signal of telecommunication, second signal of telecommunication with
And the 3rd the signal of telecommunication be in Skin icterus tester as claimed in claim 2 communication module output
The signal of telecommunication.
Described processing module, be further used for by described first signal of telecommunication, second signal of telecommunication and
3rd signal of telecommunication of two times carries out difference, then method based on linear regression obtains bilirubin concentration
Information.
Preferably, also include memory element, for storing the bilirubin received in chronological order
Concentration information.
In the neonatal percutaneous jaundice instrument that the present invention provides, light acquisition module taken at regular intervals is through new
The light that raw youngster's skin reflex goes out, thus the gallbladder after processing module is periodically processed by communication module is red
Element concentration information output, so that the terminal obtaining bilirubin concentration information can be to neonatal gallbladder
Lycopene concentration monitors in real time, it is simple to can quickly do when neonatal bilirubin concentration abnormality
Go out diagnostic reaction, reduce neonate risk to greatest extent, it is ensured that neonatal health.
Accompanying drawing explanation
In order to be illustrated more clearly that the embodiment of the present invention or technical scheme of the prior art, below
In describing embodiment, the required accompanying drawing used is briefly described, it should be apparent that under,
Accompanying drawing in the description of face is only some examples of the present invention, for those of ordinary skill in the art
From the point of view of, on the premise of not paying creative work, it is also possible to obtain other according to these accompanying drawings
Accompanying drawing.
Fig. 1 is the example structure schematic diagram of the neonatal percutaneous jaundice instrument that the present invention provides；
Fig. 2 is the double-wavelength method arrangement schematic diagram that the present invention provides；
Fig. 3 is the Spectrophotometry Method Using Three-wavelength arrangement schematic diagram that the present invention provides；
Fig. 4 is the example structure schematic diagram of the client that the present invention provides；
Fig. 5 is the embodiment flow chart of the client alarm algorithm that the present invention provides；
Fig. 6 is that the double-wavelength method that the present invention provides carries out light difference schematic diagram；
Fig. 7 is that the Spectrophotometry Method Using Three-wavelength that the present invention provides carries out light difference schematic diagram.
Detailed description of the invention
Below in conjunction with the accompanying drawing in the embodiment of the present invention, to the technical side in the embodiment of the present invention
Case is clearly and completely described, it is clear that described embodiment is only the present invention one
Divide embodiment rather than whole embodiments.Based on the embodiment in the present invention, this area is general
The every other embodiment that logical technology people is obtained under not making creative work premise, all
Belong to the scope of protection of the invention.
First aspect, the invention provides the embodiment of a kind of neonatal percutaneous jaundice instrument, such as Fig. 1
Shown in, including: light emitting module 101, light acquisition module 102, communication module 103 and control
Module 104；
Wherein,
Light emitting module 101, for pressing the frequency preset to new life under the control of control module 104
Youngster's alternate emission the first light and the second light, wherein, the first light and the second light have not
With preset wavelength, for measuring the light of neonatal bilirubin actual concentrations；
Light acquisition module 102, injects newly for taken at regular intervals under the control of control module 104
Give birth to the first light and the second light that youngster's skin is reflected out, and converted process obtains accordingly
The first signal and secondary signal；
Communication module 103, for exporting described first signal of telecommunication and second signal of telecommunication.
In the neonatal percutaneous jaundice instrument that the embodiment of the present invention provides, light acquisition module is periodically adopted
The light that collection reflects through newborn skin, thus after processing module is periodically processed by communication module
Bilirubin concentration information output so that obtain bilirubin concentration information terminal can be to new life
The bilirubin concentration of youngster monitors in real time, it is simple to can when neonatal bilirubin concentration abnormality
Quickly make diagnostic reaction, reduce neonate risk to greatest extent, it is ensured that neonatal
Healthy.
In actual applications, light emitting module 101 here and the arrangement side of light acquisition module 102
Formula is with as shown in Figure 2.Light acquisition module 102 may be located at the first light emitting module 101a and second
The both sides of light emitting module 101b.The light of the first light emitting module 101a outgoing here can be tool
There is the light of 460nm wavelength, for being inhaled by the bilirubin in newborn skin and hemoglobin
Receiving, the light of the second light emitting module 101b outgoing can be the light with 550nm wavelength, is used for
By in newborn skin and hemoglobin absorption.Light acquisition module 102 can be by through neonate
The light of the 460nm wavelength of skin reflex and the light absorption of 550nm wavelength, and turn accordingly
It is changed to first signal of telecommunication and second signal of telecommunication.
It should be noted that said method is also referred to as double-wavelength method, although and double-wavelength method can
Obtain bilirubin concentration measurement result, but a part injects the 460nm wavelength light in newborn skin
Line also can be by the melanin absorption in newborn skin, and the most in the specific implementation, the present invention is also
Provide the embodiment of a kind of modified model Skin icterus tester using Spectrophotometry Method Using Three-wavelength, specifically:
Light emitting module 101, is additionally operable under the control of control module 104 by default frequency to newly
Raw youngster's alternate emission the first light, the second light and the 3rd light, wherein, described 3rd light
Line is that wavelength is different from described first light and the second light, is used for eliminating newborn skin black
The element light on the impact of bilirubin actual concentrations；
Light acquisition module 102, is additionally operable to taken at regular intervals under the control of control module 104 and injects
The first light, the second light and the 3rd light that newborn skin is reflected out, and through turning
Change process and obtain corresponding first signal of telecommunication, second signal of telecommunication and the 3rd signal of telecommunication.
Communication module 103, is additionally operable to described first signal of telecommunication, second signal of telecommunication and the 3rd electricity
Signal exports.
Above-mentioned modified model Skin icterus tester is by increasing outgoing the 3rd light at light emitting module, newly
3rd light can be absorbed by the melanin in raw youngster's skin, thus by final calculating
Process, the impact of bilirubin actual concentrations is eliminated by newborn skin melanin, it is thus achieved that more
Measurement result accurately, provides more structurally sound foundation for neonate diagnosis.
In actual applications, the arrangement mode of light emitting module 101 and light acquisition module 102 is permissible
As it is shown on figure 3, the first granting module 101a and second here provides double with above of module 101b
Identical in wavelength.First provides module 101c can have the 3rd light of 707nm wavelength with outgoing
Line, for removing the impact for bilirubin actual concentrations of the melanin in newborn skin.
In the specific implementation, in order to measure neonate while measuring neonatal bilirubin concentration
Body temperature and pulse, the embodiment of Skin icterus tester that the present invention provides also includes temperature survey mould
Block and pulses measure module；
Wherein, temperature-measuring module, it is used for measuring neonatal body temperature and being converted to corresponding temperature
Degree information；Pulses measure module, is used for measuring neonatal pulse and being converted to corresponding pulse
Information；Communication module, is additionally operable to export described temperature information and pulse information.
By increasing temperature-measuring module and pulses measure module, it is attached to newly at Skin icterus tester
Body temperature and pulse can be measured while on raw youngster's skin, and be exported by communication module.Thus
The terminal receiving information is made to will appreciate that the current body index more comprehensively of neonate.
In the specific implementation, in the Skin icterus tester of above-mentioned introduction and modified model Skin icterus tester,
Light emitting module 101 can include several LED light sources and several optical filters, each LED
Light source is the light of outgoing preset wavelength under corresponding optical filter coordinates.
Use xenon lamp as light source compared to existing Skin icterus tester, need to include agitator,
Transformators etc., at interior complex high voltage start-up circuit, take a lot of space the most in design, and
Running voltage is high, power consumption big, and such to arrange power consumption little, and framework is simple.Additionally, this
When the Skin icterus tester of bright offer works, LED light source makes LED by posting the filter plate of correspondence
Lamp alternately flicker, incident skin is reflected out, photoelectric sensor receive, distinguished
The 460nm, 550nm and the 524nm that come or the signal of 707nm wavelength light.This is different from existing
Coaxial optical fiber probe in some jaundice instrument, its design is to use white light source, percutaneous skin
Reflection light is divided into required two wavelength by light splitting filter system again, and by contrast, the present invention will
Complicated coaxial optical fiber system is omitted, and only employs two or three LED more, reaches
Same effect.The Skin icterus tester build that the present invention is provided is small and exquisite, can directly be affixed on baby
Youngster's pleurobranch measures, easy to use, it is simple to carry, and also reduces instrument cost simultaneously.
In the specific implementation, above-mentioned light acquisition module 102 can be silicon cell, silicon light
The optical signal absorption of 300nm to 800nm wavelength taken into account by battery, converts optical signals into close with light
The point signal that degree is directly proportional.It should be appreciated that light acquisition module 102 can also pass through it
He realizes mode, and this is not especially limited by the present invention.
In the specific implementation, above-mentioned communication module 103 can be bluetooth module, is used for passing through
Described bilirubin concentration information, temperature information and pulse information are exported by bluetooth.It is to be understood that
, communication module can also implement by other means, the most wireless WIFI module, red
Outer transport module etc., this is not especially limited by the present invention.
In the specific implementation, above-mentioned control module 104 can be embedded microprocessor, compares
It is controlled consuming energy in existing employing single-chip microcomputer less, is more beneficial for extending Skin icterus tester
Cruising time.It should be appreciated that control module can also use, other power consumptions are relatively low, volume
Less control module, this is not especially limited by the present invention.
Second aspect, the invention provides a kind of client, as shown in Figure 4, and including:
Acquiring unit 401, for obtaining the signal of telecommunication received by terminal, the described signal of telecommunication is above-mentioned
The signal of telecommunication of communication module output in described neonatal percutaneous jaundice instrument；
Processing module 402, for obtaining bilirubin concentration information according to the described signal of telecommunication；
Judging unit 403, for when receiving bilirubin concentration information for the first time, if judging to know
Current bilirubin concentration information is the bilirubin concentration letter measured in neonate is born a hour
Breath, and when this bilirubin concentration information is more than first threshold, then controls terminal and send warning instruction；
Judging unit 403, when being additionally operable to receive after the first bilirubin concentration information, if sentencing
Disconnected know that current bilirubin concentration information more than Second Threshold, then controls terminal and sends warning and refer to
Show；If judging to know that current bilirubin concentration information is less than Second Threshold, and connect for adjacent twice
The interpolation of the bilirubin concentration information received more than the 3rd threshold value, then controls terminal and sends warning instruction.
It is understood that client here also has so that place terminal shows currently in real time
The function of bilirubin concentration information, enables real-time dense to neonatal bilirubin of terminal use
Degree detects.
Additionally, first threshold here is 35 μm ol/L, Second Threshold here is 205 μm ol/L,
Here the 3rd threshold value is 85.5 μm ol/L.Its judge flow process can as it is shown in figure 5, specifically,
First determine whether whether measure for the first time is to locate measurement in upper one hour, if it is, judge that concentration is
No it is more than 35 μm ol/L, is that reporting to the police is not, store the judgement after carrying out, will measure every time
Bilirubin concentration record in order, it is judged that the standard of jaundice is that single measurement concentration is the biggest
Whether the difference in 205 μm ol/L and adjacent two days concentration is more than 85.5 μm ol/L, is to report to the police.
In the specific implementation, the signal of telecommunication exported when communication module is first signal of telecommunication and second
During the signal of telecommunication, acquiring unit 401, it is further used for obtaining first signal of telecommunication received by terminal
And second signal of telecommunication；Processing module 402, is further used for described first signal of telecommunication and second
The signal of telecommunication carries out difference, then method based on linear regression obtains bilirubin concentration information.
Specifically, as shown in Figure 6, say, that processing module 402 is by the first signal of telecommunication X and
Two signal of telecommunication Y are poor, namely K=X-Y, eliminate the shadow that actual bilirubin is measured by hemoglobin
Ring, obtaining final bilirubin concentration measurement result according to equation of linear regression C=aK+b, its
In, C is bilirubin concentration value, a and b is the matching of bilirubin measured value and bilirubin standard value
Coefficient.
In the specific implementation, the signal of telecommunication exported when communication module is first signal of telecommunication, the second electricity
When signal and three signals of telecommunication, acquiring unit 401, it is further used for acquisition and is received by terminal
First signal of telecommunication, second signal of telecommunication and the 3rd signal of telecommunication；Processing module 402, uses further
In the 3rd signal of telecommunication of described first signal of telecommunication, second signal of telecommunication and two times is carried out difference,
Method based on linear regression obtains bilirubin concentration information again.
Specifically, as it is shown in fig. 7, processing module 402 be further used for by described first signal of telecommunication X,
3rd signal of telecommunication 2Z of the second signal of telecommunication Y and two times carries out difference, namely K=X-Y-2Z,
Final bilirubin concentration measurement result is obtained again based on equation of linear regression C=aK+b, wherein,
C is bilirubin concentration value, a and b is the matching system of bilirubin measured value and bilirubin standard value
Number.
In the specific implementation, the client that the present invention provides also includes memory element, on time
Between the bilirubin concentration information that receives of sequential storage.
To sum up, the client that the present invention provides can obtain the bilirubin concentration that terminal receives in real time
Information, it is achieved neonatal bilirubin concentration was monitored in real time in 24 hours, it is simple in new life
Can quickly make diagnostic reaction during youngster's bilirubin concentration exception, reduce neonate to greatest extent
Risk, it is ensured that neonatal health.
Client embodiment described above is only schematically, wherein said as separating
The unit of part description can be or may not be physically separate, shows as unit
Parts can be or may not be physical location, i.e. may be located at a place, or
Can also be distributed on multiple NE.Part therein can be selected according to the actual needs
Or all module realizes the purpose of the present embodiment scheme.Those of ordinary skill in the art are not
In the case of paying performing creative labour, i.e. it is appreciated that and implements.
Through the above description of the embodiments, those skilled in the art it can be understood that
The mode of required general hardware platform can be added by software to each embodiment to realize, certainly
Hardware can also be passed through.Based on such understanding, technique scheme is the most in other words to existing
The part having technology to contribute can embody with the form of software product, and this computer is soft
Part product can store in a computer-readable storage medium, such as ROM/RAM, magnetic disc, CD
Deng, including some instructions with so that a computer equipment (can be personal computer, take
Business device, or the network equipment etc.) perform described in some part of each embodiment or embodiment
Method.
The present invention will be described rather than carries out the present invention to it should be noted above-described embodiment
Limit, and those skilled in the art without departing from the scope of the appended claims may be used
Design alternative embodiment.In the claims, any reference between bracket should not will be located in
Symbol construction becomes limitations on claims.Word " comprises " not exclude the presence of and is not listed in right
Element in requirement or step.Word "a" or "an" before being positioned at element is not excluded for
There is multiple such element.The present invention can be by means of the hardware including some different elements
And realize by means of properly programmed computer.If listing the unit right of equipment for drying
In requirement, several in these devices can be specifically to be embodied by same hardware branch.
Word first, second and third use do not indicate that any order.Can be by these words
It is construed to title.
Last it is noted that above example is only in order to illustrate technical scheme, and
Non-to its restriction；Although the present invention being described in detail with reference to previous embodiment, ability
The those of ordinary skill in territory is it is understood that it still can be to the skill described in foregoing embodiments
Art scheme is modified, or wherein portion of techniques feature is carried out equivalent；And these are repaiied
Change or replace, not making the essence of appropriate technical solution depart from various embodiments of the present invention technical side
The spirit and scope of case.
Claims (10)
1. a neonatal percutaneous jaundice instrument, it is characterised in that including: light emitting module, light
Acquisition module, communication module and control module；
Wherein,
Described light emitting module, for pressing the frequency preset to neonate under the control of control module
Alternate emission the first light and the second light, wherein, described first light and the second light have
Different preset wavelengths, for measuring the light of neonatal bilirubin actual concentrations；
Described light acquisition module, injects new life for taken at regular intervals under the control of control module
The first light that youngster's skin is reflected out and the second light, and converted process obtains accordingly
First signal and secondary signal；
Described communication module, for exporting described first signal of telecommunication and second signal of telecommunication.
2. Skin icterus tester as claimed in claim 1, it is characterised in that
Described light emitting module, is additionally operable under the control of control module by default frequency to new life
Youngster's alternate emission the first light, the second light and the 3rd light, wherein, described 3rd light
It is different from described first light and the second light for wavelength, is used for eliminating newborn skin melanin
Light on the impact of bilirubin actual concentrations；
Described light acquisition module, is additionally operable to taken at regular intervals under the control of control module and injects newly
The first light, the second light and the 3rd light that raw youngster's skin is reflected out, and converted
Process obtains corresponding first signal of telecommunication, second signal of telecommunication and the 3rd signal of telecommunication；
Described communication module, for by described first signal of telecommunication, second signal of telecommunication and the 3rd electricity
Signal exports.
3. Skin icterus tester as claimed in claim 1, it is characterised in that described percutaneous jaundice
Instrument also includes temperature-measuring module and pulses measure module；
Described temperature-measuring module, is used for measuring neonatal body temperature and being converted to corresponding temperature
Information；
Described pulses measure module, is used for measuring neonatal pulse and being converted to corresponding pulse
Information；
Described communication module, is additionally operable to export described temperature information and pulse information.
4. the Skin icterus tester as described in claim 1-3 is arbitrary, it is characterised in that described luminescence
Module includes several LED light sources and several optical filters, and each LED light source is in correspondence
Optical filter coordinate the light of lower outgoing preset wavelength.
5. the Skin icterus tester as described in claim 1-3 is arbitrary, it is characterised in that described communication
Module is bluetooth module.
6. the Skin icterus tester as described in claim 1-3 is arbitrary, it is characterised in that described control
Module is embedded microprocessor.
7. a client, it is characterised in that including:
Acquiring unit, for obtaining the signal of telecommunication received by terminal, the described signal of telecommunication is such as power
Profit requires the signal of telecommunication of communication module output in the arbitrary described neonatal percutaneous jaundice instrument of 1-6；
Processing module, for obtaining bilirubin concentration information according to the described signal of telecommunication；
Judging unit, for when receiving bilirubin concentration information for the first time, works as if judging to know
Front bilirubin concentration information is the bilirubin concentration information measured in neonate is born one hour,
And this bilirubin concentration information more than first threshold time, then control described terminal send warning instruction；
Described judging unit, when being additionally operable to receive after the first bilirubin concentration information, if
Judge to know that current bilirubin concentration information more than Second Threshold, then controls described terminal and sends
Report to the police and indicate；If judging to know that current bilirubin concentration information is less than Second Threshold and adjacent
The interpolation of the bilirubin concentration information of twice reception is more than the 3rd threshold value, then control described terminal and send out
Go out instruction of reporting to the police.
8. client as claimed in claim 7, it is characterised in that
Described acquiring unit, be further used for obtaining first signal of telecommunication that received by terminal and
Second signal of telecommunication；
Described processing module, is further used for carrying out described first signal of telecommunication and second signal of telecommunication
Difference, then method based on linear regression obtains bilirubin concentration information.
9. client as claimed in claim 7, it is characterised in that
Described acquiring unit, be further used for obtaining received by terminal first signal of telecommunication, the
Two signals of telecommunication and the 3rd signal of telecommunication, described first signal of telecommunication, second signal of telecommunication and the 3rd electricity
Signal is the signal of telecommunication of the communication module output in Skin icterus tester as claimed in claim 2.
Described processing module, be further used for by described first signal of telecommunication, second signal of telecommunication and
3rd signal of telecommunication of two times carries out difference, then method based on linear regression obtains bilirubin concentration
Information.
10. terminal as claimed in claim 7, it is characterised in that also include memory element, use
In storing the bilirubin concentration information received in chronological order.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610334677.8A CN105943056A (en) | 2016-05-19 | 2016-05-19 | Neonate pertacuneous jaundice tester and client |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610334677.8A CN105943056A (en) | 2016-05-19 | 2016-05-19 | Neonate pertacuneous jaundice tester and client |
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|---|---|
| CN105943056A true CN105943056A (en) | 2016-09-21 |
Family
ID=56912932
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|---|---|---|---|
| CN201610334677.8A Pending CN105943056A (en) | 2016-05-19 | 2016-05-19 | Neonate pertacuneous jaundice tester and client |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106725519A (en) * | 2016-12-28 | 2017-05-31 | 济南市儿童医院 | Percutaneous neonate's target organ therapeutic drug monitoring device |
| CN107961445A (en) * | 2017-12-20 | 2018-04-27 | 深圳乐普智能医疗器械有限公司 | Skin icterus tester |
| CN109157224A (en) * | 2018-06-06 | 2019-01-08 | 电子科技大学 | A kind of pulse blood oxygen monitoring system and method increasing reference light source calibration |
| CN110811639A (en) * | 2019-11-06 | 2020-02-21 | 浙江清华柔性电子技术研究院 | Total bilirubin detection patch and total bilirubin detection system |
| CN111493838A (en) * | 2020-06-04 | 2020-08-07 | 京东方科技集团股份有限公司 | Icterus diagnosis and treatment system and computer readable storage medium |
| CN113040712A (en) * | 2021-03-08 | 2021-06-29 | 歌尔科技有限公司 | Jaundice detection device, equipment and storage medium |
| CN114259229A (en) * | 2021-12-28 | 2022-04-01 | 深圳市比特原子科技有限公司 | Multi-parameter vital sign monitoring device and method |
| US11744489B2 (en) * | 2017-05-12 | 2023-09-05 | National University Of Singapore | Noninvasive optical sensor for analyzing a level of a substance in a subject by illuminating the sclera |
| CN116746917A (en) * | 2023-05-24 | 2023-09-15 | 深圳京柏医疗科技股份有限公司 | Jaundice tester calibrating device |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1228290A (en) * | 1998-03-09 | 1999-09-15 | 北京驰名科技开发公司 | Neonatal physiological parameter monitor |
| US20020021444A1 (en) * | 1997-12-18 | 2002-02-21 | Chromatics Colorsciences Inc., | Color measurement system with color index for skin, teeth, hair and material substances |
| CN101023863A (en) * | 2007-04-20 | 2007-08-29 | 中山大学中山医学院科技开发中心 | Percutaneous detecting new-born baby icterus alarm |
| CN201899488U (en) * | 2010-12-09 | 2011-07-20 | 苏州生物医学工程技术研究所 | Portable medical monitoring system for newborn infant major diseases |
| CN102379703A (en) * | 2011-08-24 | 2012-03-21 | 苏州生物医学工程技术研究所 | Noninvasive neonatal jaundice monitoring system |
| CN102525651A (en) * | 2010-12-09 | 2012-07-04 | 苏州生物医学工程技术研究所 | Portable medical monitoring system for new arrival suffering from major disease |
| CN102564983A (en) * | 2012-02-14 | 2012-07-11 | 天津大学 | Optical detection device and method for concentration of components in turbid medium based on limited range wavelength method |
| CN103300927A (en) * | 2013-05-30 | 2013-09-18 | 重庆宇珂医疗设备有限公司 | Man-machine data exchange and database management newborn monitoring bed |
| CN205849458U (en) * | 2016-05-19 | 2017-01-04 | 苏州阿尔星科电子科技有限公司 | Neonatal percutaneous jaundice instrument |
-
2016
- 2016-05-19 CN CN201610334677.8A patent/CN105943056A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020021444A1 (en) * | 1997-12-18 | 2002-02-21 | Chromatics Colorsciences Inc., | Color measurement system with color index for skin, teeth, hair and material substances |
| CN1228290A (en) * | 1998-03-09 | 1999-09-15 | 北京驰名科技开发公司 | Neonatal physiological parameter monitor |
| CN101023863A (en) * | 2007-04-20 | 2007-08-29 | 中山大学中山医学院科技开发中心 | Percutaneous detecting new-born baby icterus alarm |
| CN201899488U (en) * | 2010-12-09 | 2011-07-20 | 苏州生物医学工程技术研究所 | Portable medical monitoring system for newborn infant major diseases |
| CN102525651A (en) * | 2010-12-09 | 2012-07-04 | 苏州生物医学工程技术研究所 | Portable medical monitoring system for new arrival suffering from major disease |
| CN102379703A (en) * | 2011-08-24 | 2012-03-21 | 苏州生物医学工程技术研究所 | Noninvasive neonatal jaundice monitoring system |
| CN102564983A (en) * | 2012-02-14 | 2012-07-11 | 天津大学 | Optical detection device and method for concentration of components in turbid medium based on limited range wavelength method |
| CN103300927A (en) * | 2013-05-30 | 2013-09-18 | 重庆宇珂医疗设备有限公司 | Man-machine data exchange and database management newborn monitoring bed |
| CN205849458U (en) * | 2016-05-19 | 2017-01-04 | 苏州阿尔星科电子科技有限公司 | Neonatal percutaneous jaundice instrument |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106725519A (en) * | 2016-12-28 | 2017-05-31 | 济南市儿童医院 | Percutaneous neonate's target organ therapeutic drug monitoring device |
| US11744489B2 (en) * | 2017-05-12 | 2023-09-05 | National University Of Singapore | Noninvasive optical sensor for analyzing a level of a substance in a subject by illuminating the sclera |
| CN107961445A (en) * | 2017-12-20 | 2018-04-27 | 深圳乐普智能医疗器械有限公司 | Skin icterus tester |
| CN107961445B (en) * | 2017-12-20 | 2024-01-26 | 深圳乐普智能医疗器械有限公司 | Percutaneous jaundice instrument |
| CN109157224A (en) * | 2018-06-06 | 2019-01-08 | 电子科技大学 | A kind of pulse blood oxygen monitoring system and method increasing reference light source calibration |
| CN110811639A (en) * | 2019-11-06 | 2020-02-21 | 浙江清华柔性电子技术研究院 | Total bilirubin detection patch and total bilirubin detection system |
| CN110811639B (en) * | 2019-11-06 | 2023-11-21 | 浙江清华柔性电子技术研究院 | Total bilirubin detection patch and total bilirubin detection system |
| WO2021244253A1 (en) * | 2020-06-04 | 2021-12-09 | 京东方科技集团股份有限公司 | Jaundice diagnosis and treatment system and computer-readable storage medium |
| CN111493838B (en) * | 2020-06-04 | 2023-04-07 | 京东方科技集团股份有限公司 | Jaundice diagnosis and treatment system and computer readable storage medium |
| CN111493838A (en) * | 2020-06-04 | 2020-08-07 | 京东方科技集团股份有限公司 | Icterus diagnosis and treatment system and computer readable storage medium |
| CN113040712A (en) * | 2021-03-08 | 2021-06-29 | 歌尔科技有限公司 | Jaundice detection device, equipment and storage medium |
| CN114259229A (en) * | 2021-12-28 | 2022-04-01 | 深圳市比特原子科技有限公司 | Multi-parameter vital sign monitoring device and method |
| CN116746917A (en) * | 2023-05-24 | 2023-09-15 | 深圳京柏医疗科技股份有限公司 | Jaundice tester calibrating device |
| CN116746917B (en) * | 2023-05-24 | 2024-02-23 | 深圳京柏医疗科技股份有限公司 | Jaundice tester calibrating device |
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