CN105930655A - Method used for increasing reporting rate of adverse drug reactions of clinical drugs - Google Patents
Method used for increasing reporting rate of adverse drug reactions of clinical drugs Download PDFInfo
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Abstract
The invention provides a method used for increasing a reporting rate of adverse drug reactions of clinical drugs, and belongs to the technical field of medical systems. According to the method, an adverse drug reaction (ADR) case is monitored through reverse screening, and a data terminal used for the ADR case processes compatibility of uploaded drugs, eliminates a nidus time limit and determines a check image of the ADR case, so that the technical effect of improving the effect of dexamethasone injection, vitamin C injection, calcium gluconate injection and loratadine tablets for the ADR case is achieved, and the technical problems of ADR and the like caused by unreasonable drug compatibility of the clinical drugs are avoided; and by use of the method provided by the invention, the working efficiency can be improved, the ADR reporting work of medical personnel can be effectively guided and supervised, and the phenomena of non-reporting and underreporting are greatly reduced, so that the method is worthy of nationwide popularization.
Description
Technical field
The invention belongs to medical system technical field, particularly relate to a kind of for improving clinical application medicine not
Good reaction reports the method for rate.
Background technology
Adverse drug reaction (adverse drug reactions is called for short ADR) is important clinical problem.
Adverse drug reaction refers to that the medicine of normal dose is for preventing, diagnose, treat disease or regulation physiological function
Time harmful and unrelated with medication mesh reaction of occurring, almost all of medicine all can cause bad reaction, only
The degree being reaction is different with incidence.Along with drug variety is increasing, the incidence of adverse drug reaction
Increase the most year by year.Adverse drug reaction the most also can cause drug induced disease, except a few peoples are from taking medicine beyond the region of objective existence,
Adverse drug reaction is mainly administered caused, so some drug induced disease also belongs to iatrogenic disease by doctor.
Avoid although some adverse drug reaction is more difficult, but quite a few be due to clinical application medicine compatibility not
The most caused.Within 2014, national Adverse reaction monitoring network receives " adverse drug reaction/event account "
132.8 ten thousand parts, the report of medical institutions accounts for 82.2%, it is seen that adverse drug reaction (ADR) report of China
Based on hospital, the attention degree that ADR is reported by medical personnel is particularly important.But hospital of China ADR at present
Reporting is independently to report, and reports rate low, does not reports, fails to report situation seriously, and patient produces the event of bad reaction
Increase year by year, process such dispute and also consume many time and efforts of hospital, and can not be effective
Avoid the unreasonable caused adverse drug reaction of medicine compatibility of medication.Based on above-mentioned situation, find a kind of letter
The method that single feasible raising ADR reports rate is particularly important, but in prior art, lacks such technology of solution and ask
The necessary technology means of topic.
Therefore need badly in the middle of prior art and to design new technical scheme to solve this problem.
Summary of the invention
The technical problem to be solved: reporting for ADR in prior art is independently to report, and reports
Rate is low, does not reports, fails to report situation seriously, and patient produces the event of bad reaction and increases year by year, and can not have
The technical problems such as the unreasonable caused adverse drug reaction of medicine compatibility avoiding medication of effect, the present invention provides
A kind of for improve clinical application adverse drug reaction report the method for rate for solving this class technical problem,
Upload medicine compatibility for ADR case data terminal processes, eliminate the focus time limit and determine the school of ADR case
Core image, thus improve Dexamethasone Injection, vitamin C injection, calcium gluconate injection and chlorine
His stator medicine of thunder produces effects rate for ADR case.
A kind of for improving the method that clinical application adverse drug reaction reports rate, it is characterized in that: the method bag
Include following steps,
A kind of for improving the method that clinical application adverse drug reaction reports rate, it is characterized in that: the method bag
Include following steps,
Step one, the first aid medicine determining generation ADR adverse drug reaction use and Claritin
First the exclusive central processing unit of ADR passes through CAN hospital internal LAN, from first aid medicine and
Claritin database transfers nomenclature of drug,
Secondly from case database, first aid medicine and Claritin Clinical practice data are transferred,
Again the concrete data input ADR medicining condition obtained is analyzed module,
Finally obtain Dexamethasone Injection, vitamin C injection, calcium gluconate injection and chlorine thunder he
Stator is monitoring medicine；
Step 2, a line doctor are by Dexamethasone Injection, vitamin C injection, calcium gluconae injection
Liquid and loratadine tablet Clinical practice data, input ADR case screening module, it is thus achieved that ADR cause and medication
Data, and be stored in ADR basic data hard disk；
Step 3, from ADR basic data hard disk, transfer ADR basic data, import ADR comparing module,
ADR comparing module, according to there is ADR adverse drug reaction medication handbook standard, generates ADR clinic image medium
Figure；
Step 4, general generate ADR clinic image medium figure and import anti-examination module；
Step 5, transfer from clinical case reported data storehouse ADR clinical case reported data input anti-examination mould
Block；
The exclusive central processing unit of step 6, ADR carries out anti-examination process by anti-examination module, it is thus achieved that on ADR
Report rate and qualification rate result data；
The exclusive central processing unit of step 7, ADR generates ADR and reports rate and qualification rate anti-screening results image；
Step 8, a line doctor transfer ADR by hospital internal key and report rate and the anti-screening results of qualification rate
Image is downloaded；
Step 9, a line doctor handle case according to unit time period and report rate and qualification rate anti-examination knot with ADR
Really image comparison, uploads medicine compatibility for ADR case data terminal processes, eliminates the focus time limit and determine
The check image of ADR case.
By above-mentioned design, the present invention can bring following beneficial effect: for can not in prior art
Effectively avoid unreasonable caused this class technical problem of adverse drug reaction of medicine compatibility of medication, this
Bright offer is a kind of for improving the method that clinical application adverse drug reaction reports rate, and the method is by anti-examination
There is the case of bad reaction in monitoring, thus realizes improving a line doctor and determine ADR case qualification rate, minimizing
Eliminate the focus time limit, and improve Dexamethasone Injection, vitamin C injection, calcium gluconate injection
ADR case produced effects the technique effect of rate with loratadine tablet medicine.The method that the present invention provides is not only
Can improve operating efficiency, also can effectively guidance and supervision medical personnel ADR report work, significantly subtract
Do not report less, fail to report phenomenon, be worth the whole nation to be promoted.
Accompanying drawing explanation
The invention will be further described with detailed description of the invention in explanation below in conjunction with the accompanying drawings:
Fig. 1 is that the present invention is a kind of for improving the flow chart that clinical application adverse drug reaction reports the method for rate.
Detailed description of the invention
A kind of for improving the method that clinical application adverse drug reaction reports rate, as it is shown in figure 1, the method
Comprise the following steps,
Step one, the first aid medicine determining generation ADR adverse drug reaction use and Claritin
First the exclusive central processing unit of ADR passes through CAN hospital internal LAN, from first aid medicine and
Claritin database transfers nomenclature of drug,
Secondly from case database, first aid medicine and Claritin Clinical practice data are transferred,
Again the concrete data input ADR medicining condition obtained is analyzed module,
Finally obtain Dexamethasone Injection, vitamin C injection, calcium gluconate injection and chlorine thunder he
Stator is monitoring medicine；
Step 2, a line doctor are by Dexamethasone Injection, vitamin C injection, calcium gluconae injection
Liquid and loratadine tablet Clinical practice data, input ADR case screening module, it is thus achieved that ADR cause and medication
Data, and be stored in ADR basic data hard disk；
Step 3, from ADR basic data hard disk, transfer ADR basic data, import ADR comparing module,
ADR comparing module, according to there is ADR adverse drug reaction medication handbook standard, generates ADR clinic image medium
Figure；
Step 4, general generate ADR clinic image medium figure and import anti-examination module；
Step 5, transfer from clinical case reported data storehouse ADR clinical case reported data input anti-examination mould
Block；
The exclusive central processing unit of step 6, ADR carries out anti-examination process by anti-examination module, it is thus achieved that on ADR
Report rate and qualification rate result data；
The exclusive central processing unit of step 7, ADR generates ADR and reports rate and qualification rate anti-screening results image；
Step 8, a line doctor transfer ADR by hospital internal key and report rate and the anti-screening results of qualification rate
Image is downloaded；
Step 9, a line doctor handle case according to unit time period and report rate and qualification rate anti-examination knot with ADR
Really image comparison, uploads medicine compatibility for ADR case data terminal processes, eliminates the focus time limit and determine
The check image of ADR case.
The method provided the present invention below in conjunction with concrete data is described further:
1, the first aid medicine occurring ADR to use and Claritin are determined
With in 12 in " Rescue carrigae medicine and medicine base directory " that Department of Public Health of Jilin Province issues for 2009
Medicine is attached most importance to monitoring medicine, is shown in Table 1.
Table 1 occurs ADR to use related drugs
Randomly draw in July, 2014, October, case in November, occur to use 12 kinds of medicine feelings during ADR
Condition is shown in Table 2.
Table 2 occurs ADR to use drug condition
As seen from the above table, drug withdrawal and the case totally 650 parts of No. 1-No. 12 medicines of use during generation ADR, wherein
Use sequence number 1,2,3 three kind of medicine most, totally 368 parts, next to that use 4,6, No. 8 medicines of sequence number
And Claritin.Examination case-finding, these medicines above-mentioned are used alone less, often several drugs
It is used in combination.In order to reduce the kind of medicine further, we are again by No. 4-No. 12 medicines and No. 1-No. 3
The situation that is used in combination of medicine is analyzed, and is shown in Table 3.
There is ADR medicining condition analysis in table 3
Found that in 4 kinds of-12 kinds of medicines except in the case of Loratadine is used alone, other medicines all with
One or more combinations of Dexamethasone Injection, vitamin C injection, calcium gluconate injection, it is seen that
The use of above-mentioned 4 kinds of medicines can contain the use of other drug completely.Therefore we determined that dexamethasone is noted
Penetrate liquid, vitamin C injection, calcium gluconate injection and loratadine tablet to attach most importance to monitoring medicine.Logical
Cross this process, emphasis is monitored medicine and is reduced to 4 kinds by 12 kinds, as a example by 2014 three months (table 2),
The ADR case needing examination has been reduced to 368 parts by 650 parts, greatly reduces workload.
2, inpatient case screening results in 2014,2015
Inpatient in 2014,2015 is used Dexamethasone Injection, vitamin C injection, glucose
The case of acid calcium parenteral solution and loratadine tablet carries out examination, occurs the situation of ADR to be shown in Table 4.Patient is used
The reason of first aid medicine and Claritin is reviewed, and is conditions of patients development need, or because using it
He occurs in that in drug treatment that ADR uses.
Table 4 2014,2015 screens case scenario
As seen from the above table, 2014 and 2015 are used the selective examination rate of 4 kinds of medicines of emphasis monitoring respectively
Being 20% and 22.5%, the incidence of ADR is respectively 3.8% and 3.92%.We can be according to analyzing gained
ADR incidence, and then supervise each section office ADR and report the accuracy of rate.
3, analysis of cases ADR occurring in 2014,2015
The method using retrospective study, by hospital HIS system, obtains 2014,2015 examination
The ADR case in January-May is analyzed.Centralizing inspection in June, 2015-December there is ADR in inpatient
Situation.
Within 2014, ADR reports rate and qualification rate to be 25.47% and 23.85%.On in January, 2015-May ADR
Report rate and qualification rate are 30.24% and 27.04%.Monthly inpatient case is carried out from June, 2015
ADR examination, application uses the method that 4 kinds of emphasis monitoring medicines carry out examination case, to failing to report in examination, cherishing
Doubt drug allergy, report case no record and report medicine and doctor's advice in record the case and relevant clinical not being inconsistent
Section office are linked up, and actively repay.Through effective communication and the enforcement of Supervision Measures, in June, 2015-December ADR
Reporting rate and qualification rate is 91.16% and 87.29%.Substantially increase bad reaction and report rate, be shown in Table 5.
Table ADR in 5 2014,2015 reports situation
To sum up can be summarized as following three points:
1, emphasis medicine is determined
Clinical generation can take different measures according to its order of severity difference during ADR.Slight ADR, drug withdrawal
After can disappear without processing symptom；When there is allergic symptom, drug withdrawal the most also should use Claritin
Symptomatic treatment；Ratio is more serious, needs first aid medicine to correct or alleviates its clinical symptoms, then we are right
The case using Claritin and first aid medicine carries out anti-examination, can find out except undressed slight ADR
Outer whole ADR events.Therefore we tentatively draft " Rescue carrigae Department of Public Health of Jilin Province issued for 2009
Medicine and medicine base directory " in 12 kinds of first aid medicines and Claritin as emphasis medicine.
2, screen one by one
Extract in July, 2014, October, case in November, during to generation ADR, use these 12 kinds of medicines
Situation carries out statistical analysis, finds to exist the situation of drug combination, examination Dexamethasone Injection, vitamin C
Parenteral solution, calcium gluconate injection and 4 kinds of medicines of loratadine tablet can contain except undressed slightly
Whole ADR events outside ADR.By this process, emphasis medicine is reduced to 4 kinds by 12 kinds, needs examination
ADR case is only the 20% of sum, greatly reduces workload, improves operating efficiency.
3, statistical analysis
We extract the case using these 4 kinds of medicines 2014,2015 and carry out bad reaction examination, by ADR
The actual ADR incidence reporting rate and anti-examination gained contrasts, and finds that annual adverse reaction rate is equal
About 3.9%, preliminary judgement clinic can be carried out according to this and report whether ADR exists the situation do not reported, fail to report, with
Shi Lianhe medical department reports situation to exercise supervision to future clinical ADR is conscious.
Social benefit:
The first, save effective time: from annual total case, the case of examination 20% just can contain most of
The generation of bad reaction.
The second, guarantee to report quality: when reporting the ADR of ADR monitoring center of country to go wrong, mend in time
Fill, revise and feed back；It is imperfect that each section office report ADR content to fill in, and patient information is commented with medicine relevance
Valency is complete, and bad reaction process prescription is the most careful, suspects that medicine information is filled in and incomplete believes with ADR in time
Breath person links up, and supplements complete and reports；Of that month examination finds there is record in case and suspects that generation ADR does not has
Linking up with associated department of report, actively repays, and ADR reports rate and qualification rate to be obviously improved.
3rd, strengthening reports consciousness: Pharmaceutical Department is combined with department of medical administration, to the ADR not reporting, fail to report and reporting
The non-registered section office of case link up with bonus, realize with the safe medication that this drives crew.
In a word, the present invention is the technical problems such as monitoring adverse drug reaction, it is provided that one is used for improving clinical use
Medicine adverse drug reaction reports the method for rate, and the method occurs the case of bad reaction by anti-examination monitoring,
Thus reach to improve a line doctor and determine ADR case qualification rate, reduce the elimination focus time limit, and improve ground plug
Rice loose parenteral solution, vitamin C injection, calcium gluconate injection and loratadine tablet medicine are for ADR
The technique effect of the rate of producing effects of case.The method that the present invention provides is possible not only to improve operating efficiency, also can have
The guidance and supervision medical personnel ADR of effect reports work, greatly reduces and does not report, fails to report phenomenon, is worth complete
State promotes.
Claims (1)
1., for improving the method that clinical application adverse drug reaction reports rate, it is characterized in that: the method
Comprise the following steps,
Step one, the first aid medicine determining generation ADR adverse drug reaction use and Claritin
First the exclusive central processing unit of ADR passes through CAN hospital internal LAN, from first aid medicine and
Claritin database transfers nomenclature of drug,
Secondly from case database, first aid medicine and Claritin Clinical practice data are transferred,
Again the concrete data input ADR medicining condition obtained is analyzed module,
Finally obtain Dexamethasone Injection, vitamin C injection, calcium gluconate injection and chlorine thunder he
Stator is monitoring medicine；
Step 2, a line doctor are by Dexamethasone Injection, vitamin C injection, calcium gluconae injection
Liquid and loratadine tablet Clinical practice data, input ADR case screening module, it is thus achieved that ADR cause and medication
Data, and be stored in ADR basic data hard disk；
Step 3, from ADR basic data hard disk, transfer ADR basic data, import ADR comparing module,
ADR comparing module, according to there is ADR adverse drug reaction medication handbook standard, generates ADR clinic image medium
Figure；
Step 4, general generate ADR clinic image medium figure and import anti-examination module；
Step 5, transfer from clinical case reported data storehouse ADR clinical case reported data input anti-examination mould
Block；
The exclusive central processing unit of step 6, ADR carries out anti-examination process by anti-examination module, it is thus achieved that on ADR
Report rate and qualification rate result data；
The exclusive central processing unit of step 7, ADR generates ADR and reports rate and qualification rate anti-screening results image；
Step 8, a line doctor transfer ADR by hospital internal key and report rate and the anti-screening results of qualification rate
Image is downloaded；
Step 9, a line doctor handle case according to unit time period and report rate and qualification rate anti-examination knot with ADR
Really image comparison, uploads medicine compatibility for ADR case data terminal processes, eliminates the focus time limit and determine
The check image of ADR case.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108921427A (en) * | 2018-06-29 | 2018-11-30 | 上海中医药大学附属曙光医院 | A kind of traditional Chinese medicine service monitoring Data Quality Assessment Methodology |
| CN109411040A (en) * | 2018-11-06 | 2019-03-01 | 上海市嘉定区中心医院 | A kind of processing method of medical information, apparatus and system |
| CN109637671A (en) * | 2018-11-13 | 2019-04-16 | 郭金荣 | A kind of Adverse reaction monitoring management analysis method |
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| CN103646185A (en) * | 2013-12-25 | 2014-03-19 | 顾德国 | Adverse drug reaction (ADR) report quality evaluation system and ADR report quality evaluation method |
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| CN103646185A (en) * | 2013-12-25 | 2014-03-19 | 顾德国 | Adverse drug reaction (ADR) report quality evaluation system and ADR report quality evaluation method |
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| C.A.NARANJO ET AL: "《A method for estimating the probability of adverse drug reactions》", 《CLIN.PHARMACLO.THER》 * |
| VIVEK V.BHOSALE ETC: ""Adeverse drug reaction monitoring"", 《CURRENT SCIENCE》 * |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108921427A (en) * | 2018-06-29 | 2018-11-30 | 上海中医药大学附属曙光医院 | A kind of traditional Chinese medicine service monitoring Data Quality Assessment Methodology |
| CN109411040A (en) * | 2018-11-06 | 2019-03-01 | 上海市嘉定区中心医院 | A kind of processing method of medical information, apparatus and system |
| CN109637671A (en) * | 2018-11-13 | 2019-04-16 | 郭金荣 | A kind of Adverse reaction monitoring management analysis method |
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