CN105902290B - The Ni-based marmem tissue closure folder of titanium - Google Patents
The Ni-based marmem tissue closure folder of titanium Download PDFInfo
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- CN105902290B CN105902290B CN201610407973.6A CN201610407973A CN105902290B CN 105902290 B CN105902290 B CN 105902290B CN 201610407973 A CN201610407973 A CN 201610407973A CN 105902290 B CN105902290 B CN 105902290B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
- A61B17/083—Clips, e.g. resilient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00862—Material properties elastic or resilient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/16—Materials with shape-memory or superelastic properties
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Abstract
The present invention relates to a kind of Ni-based marmem tissue closure folders of titanium, it is the band being closed made of with the Ni-based shape memory alloy material of hyperelastic titanium to be closed folder, and the band of closure is in turn connected to form disk like layout or bowl-shape layout by least three outer arc segments of staggered arrangement and the interior segmental arc head and the tail of identical quantity.Tissue closure folder of the present invention, for the excision of tissue perforation, anal fistula internal orifice, the closure of hemorrhage of digestive tract and polyp tissue.Present invention utilizes the shape memory characteristic and super-elasticity of titanium Ni based memory alloy, opening less than set temperature or under external force, be closed automatically after higher than set temperature or external force unloading, lesion carried out continuing Self-pressurizing agri to achieve the purpose that treatment.Structure very simple of the present invention, processing technology is simple, surgical procedure is simple, can finally accomplish internal foreign.
Description
Technical field
It is pressed from both sides the present invention relates to a kind of tissue closure more particularly to a kind of using made of the Ni-based shape memory alloy material of titanium
Tissue closure presss from both sides.The tissue closure folder of the present invention, for tissue perforation, anal fistula internal orifice, the closure of hemorrhage of digestive tract and polyp
The excision of tissue.
Background technology
The tissue closer clinically used at present is as assistor using disposable alimentary canal closer
Tool, such as do anal fistula internal orifice be closed when using stainless steel lag screws by notch coincide or using purse string suture method to anal fistula internal orifice into
Row is closed.The device is invasive surgery instrument, and patient will suffer exquisite pain, and stainless steel lag screws by prolonged stay in human body
It is interior or even cause operative failure.
Invention content
It is an object of the present invention to provide a kind of Ni-based marmem tissue closure folders of titanium, and it makes use of the Ni-based memories of titanium to close
The shape memory characteristic and super-elasticity of gold are being opened less than set temperature or under external force, higher than set temperature or outer
It is closed automatically after power unloading, lesion is carried out continuing Self-pressurizing agri to achieve the purpose that treatment.
The present invention technical solution be:
A kind of Ni-based marmem tissue closure folder of titanium, is made of the Ni-based shape memory alloy material of titanium, special
Part is, including the closure clip main body being made of the band being closed;The band of the closure is by outside staggered at least three
The round and smooth connection successively of the interior segmental arc of segmental arc and identical quantity head and the tail;It is described closure clip main body for it is planar layout, disk like layout or
Bowl-shape layout.
To ensure closure effect, above-mentioned closure folder, which further includes to be arranged at the top of each interior segmental arc and be directed toward, is closed folder center
Detent projection.
The quantity of the outer arc segments of above-mentioned closure folder can be 3,4,5,6 or 8.
To further enhance closure effect, above-mentioned closure folder may also include identical with outer arc segment number and one-to-one flat
Row folder;The parallel folder includes two clamps being arranged in parallel;The fixing end of described two clamps respectively with the both ends of outer arc segments
It is connected, on-fixed end is located in the outer arc segments area defined.
To prevent closing course is favorite from coming off outside, the opposite side of above-mentioned two clamp is respectively arranged with meshing device;Institute
The tine locations of at least one pointed tooth and the pointed tooth and opposite clamp that meshing device includes evagination are stated to be staggered or including outer
The quantity shape of the pointed tooth of convex at least one pointed tooth and the groove of indent and the groove and opposite clamp match or
The round and smooth slot and the round and smooth slot of at least one round and smooth protrusion and indent including evagination and the round and smooth protrusion of opposite clamp
Quantity shape matches.
Diameter of a circle where the top of above-mentioned all outer arc segments is 10-20mm, the top of all interior segmental arcs or top dentation
Diameter of a circle where raised is 1-4mm;The coning angle for being closed clip main body is 120-180 °, and the spacing of described two clamps is
0.5-2mm。
Diameter of a circle where the top of above-mentioned all outer arc segments is 12-16mm, the top of all interior segmental arcs or top dentation
Diameter of a circle where raised is 1-3mm;The coning angle of the band of the closure is 160 °.
The beneficial effects of the invention are as follows:
1st, it is band-like to close to be closed folder by the present invention, by being staggered multiple outer arc segments and interior segmental arc joins end to end, ties
Structure very simple.
2nd, the present invention is closed folder and cuts into closing band with the Ni-based marmem plank of titanium or tubing, is handled through memory
It can be used, processing technology is simple.
3rd, in order to enhance closure effect, the present invention is closed folder and employs level Four anti-drop device:
The first order is to be closed folder ontology, has hyperelastic titanium Ni-based marmem when using higher than memory temperature
Material is made, and the memory temperature for setting material is less than body temperature, and when closure folder enters in human body, material shows super-elasticity, to
Contract persistently pressurizes to tissue;
The second level is provided at the top of each interior segmental arc and is directed toward the detent projection for being closed folder center, can be pierced into tissue
Portion prevents closure folder from coming off;
The third level is the parallel folder of setting, and comprehensive grip tissue improves closure effect;
The fourth stage is to set meshing device on parallel folder, can be into one by the meshing device being oppositely arranged on parallel folder
Grip tissue is walked, can prevent the accident for being closed folder from coming off to greatest extent.
4th, surgical procedure of the present invention is simple.When the present invention is used for tissue closure, it is clipped in being closed outside tissue perforation internal orifice
All tissues, the detent projection being closed in the interior segmental arc or interior segmental arc of folder treat anastomosed tissue internal orifice periphery group under body temperature effect
Carry out Self-pressurizing agri is knitted, tissue internal orifice peripheral tissues do not form new wound, keep good while tissue tension is overcome
Blood circulation has promoted the closure of tissue perforation internal orifice, good operation effect.
5th, the present invention, which is closed, is clipped in the good blood circulation of histozoic one end holding, and tissue perforation mouth has been promoted to heal
While, the other end the clamped tissue necrosis caused by tissue ischemia makes tissue closure press from both sides Automatic-falling, can finally accomplish body
Foreign matter is not stayed inside.
6th, present invention closure is clipped in tissue closure folder in special circumstances and can also be removed with tool, can also be chronically implanted in vivo.
7th, the dual function of excision and engaging tissue in a organized way of the invention.
8th, the present invention is using to cardioid closed mode, it can be achieved that comprehensive closure, than closing for existing parallel closed mode
It is good to close effect.
9th, the present invention is atraumatic surgical instrument.
Description of the drawings
Fig. 1 to Fig. 4 is the schematic diagram for the tissue closure folder for including 3 outer arc segments;Wherein:
Fig. 1 is the front view remembered before deformation;
Fig. 2 is the three-dimensional effect diagram remembered before deformation, it can be seen that band is generally aligned in the same plane;
Fig. 3 be remember deformation after look up design sketch, it can be seen that interior segmental arc offsets to one side;
Fig. 4 is the three-dimensional effect diagram remembered after deformation, it can be seen that interior segmental arc offsets to one side;
Fig. 5 to Fig. 8 is the schematic diagram for the tissue closure folder for including 3 outer arc segments and interior segmental arc top tape detent projection;Its
In:
Fig. 5 is the front view remembered before deformation;
Fig. 6 is the three-dimensional effect diagram remembered before deformation, it can be seen that band is generally aligned in the same plane;
Fig. 7 be remember deformation after look up design sketch, it can be seen that interior segmental arc offsets to one side;
Fig. 8 is the three-dimensional effect diagram remembered after deformation, it can be seen that interior segmental arc offsets to one side;
Fig. 9 to Figure 12 is the schematic diagram for the tissue closure folder for including 4 outer arc segments;Wherein:
Fig. 9 is the front view remembered before deformation;
Figure 10 is the three-dimensional effect diagram remembered before deformation, it can be seen that band is generally aligned in the same plane;
Figure 11 be remember deformation after look up design sketch, it can be seen that interior segmental arc offsets to one side;
Figure 12 is the three-dimensional effect diagram remembered after deformation, it can be seen that interior segmental arc offsets to one side;
Figure 13 to Figure 16 is the schematic diagram for the tissue closure folder for including 4 outer arc segments and interior segmental arc top tape detent projection;
Wherein:
Figure 13 is the front view remembered before deformation;
Figure 14 is the three-dimensional effect diagram remembered before deformation, it can be seen that band is generally aligned in the same plane;
Figure 15 be remember deformation after look up design sketch, it can be seen that interior segmental arc offsets to one side;
Figure 16 is the three-dimensional effect diagram remembered after deformation, it can be seen that interior segmental arc offsets to one side;
Figure 17 to Figure 20 is the schematic diagram for the tissue closure folder for including 5 outer arc segments;Wherein:
Figure 17 is the front view remembered before deformation;
Figure 18 is the three-dimensional effect diagram remembered before deformation, it can be seen that band is generally aligned in the same plane;
Figure 19 be remember deformation after look up design sketch, it can be seen that interior segmental arc offsets to one side;
Figure 20 is the three-dimensional effect diagram remembered after deformation, it can be seen that interior segmental arc offsets to one side;
Figure 21 to Figure 24 is the schematic diagram for the tissue closure folder for including 5 outer arc segments and interior segmental arc top tape detent projection;
Wherein:
Figure 21 is the front view remembered before deformation;
Figure 22 is the three-dimensional effect diagram remembered before deformation, it can be seen that band is generally aligned in the same plane;
Figure 23 be remember deformation after look up design sketch, it can be seen that interior segmental arc offsets to one side;
Figure 24 is the three-dimensional effect diagram remembered after deformation, it can be seen that interior segmental arc offsets to one side;
Figure 25 to Figure 28 is the schematic diagram for the tissue closure folder for including 6 outer arc segments;Wherein:
Figure 25 is the front view remembered before deformation;
Figure 26 is the three-dimensional effect diagram remembered before deformation, it can be seen that band is generally aligned in the same plane;
Figure 27 be remember deformation after look up design sketch, it can be seen that interior segmental arc offsets to one side;
Figure 28 is the three-dimensional effect diagram remembered after deformation, it can be seen that interior segmental arc offsets to one side;
Figure 29 to Figure 32 is the schematic diagram for the tissue closure folder for including 6 outer arc segments and interior segmental arc top tape detent projection;
Wherein:
Figure 29 is the front view remembered before deformation;
Figure 30 is the three-dimensional effect diagram remembered before deformation, it can be seen that band is generally aligned in the same plane;
Figure 31 be remember deformation after look up design sketch, it can be seen that interior segmental arc offsets to one side;
Figure 32 is the three-dimensional effect diagram remembered after deformation, it can be seen that interior segmental arc offsets to one side;
Figure 33 to Figure 36 is the schematic diagram for the tissue closure folder for including 8 outer arc segments;Wherein:
Figure 33 is the front view remembered before deformation;
Figure 34 is the three-dimensional effect diagram remembered before deformation, it can be seen that band is generally aligned in the same plane;
Figure 35 be remember deformation after look up design sketch, it can be seen that interior segmental arc offsets to one side;
Figure 36 is the three-dimensional effect diagram remembered after deformation, it can be seen that interior segmental arc offsets to one side;
Figure 37 to Figure 40 is the schematic diagram for the tissue closure folder for including 8 outer arc segments and interior segmental arc top tape detent projection;
Wherein:
Figure 37 is the front view remembered before deformation;
Figure 38 is the three-dimensional effect diagram remembered before deformation, it can be seen that band is generally aligned in the same plane;
Figure 39 be remember deformation after look up design sketch, it can be seen that interior segmental arc offsets to one side;
Figure 40 is the three-dimensional effect diagram remembered after deformation, it can be seen that interior segmental arc offsets to one side;
Figure 41 is to include being provided on the parallel folder of 4 outer arc segments, interior segmental arc top tape detent projection, 4, band and parallel folder
The schematic diagram of the tissue closure folder of detent projection;
Figure 42 is to include being provided on the parallel folder of 4 outer arc segments, interior segmental arc top tape detent projection, 4, band and parallel folder
The schematic diagram of the tissue closure of detent projection and groove folder;
Figure 43 is to include being provided on the parallel folder of 4 outer arc segments, interior segmental arc top tape detent projection, 4, band and parallel folder
The tissue perforation internal orifice of round and smooth protrusion and round and smooth slot is closed the schematic diagram of folder;
Figure 44 is to include being provided on the parallel folder of 3 outer arc segments, interior segmental arc top tape detent projection, 3, band and parallel folder
The tissue perforation internal orifice of round and smooth protrusion and round and smooth slot is closed the opening state schematic diagram of folder;
Figure 45 is to include being provided on the parallel folder of 3 outer arc segments, interior 3 segmental arc top tape detent projection, 3, band and parallel folder
The tissue perforation internal orifice of round and smooth protrusion and round and smooth slot is closed the schematic diagram of folder;
Figure 46 is the stereoscopic effect schematic diagram that tissue perforation internal orifice is closed folder in Figure 45;
Reference numeral:91- outer arc segments, segmental arc in 92-, 93- detent projections, 94- clamps, 941- pointed tooths, 942-V shape slots,
The round and smooth protrusions of 943-, the round and smooth grooves of 944-.
Specific embodiment
The Ni-based marmem tissue closure folder of titanium of the present invention, including being closed clip main body, it is that titanium is Ni-based to be closed clip main body
The band being closed made of shape memory alloy material, band is by staggered at least three outer arc segments and identical quantity
Segmental arc head and the tail be connected in sequence it is planar layout, disk like layout or bowl-shape layout;The disk like is laid out or the closure of bowl-shape layout
Band ranging from 120-180 ° of coning angle, most preferably 160 °.Have when being closed band by being higher than memory temperature hyperelastic
The Ni-based shape memory alloy material of titanium is processed as the memory character clinically needed.When external force acts on or less than memory temperature when can
Change its shape, refresh memory shape when being higher than memory temperature after external force unloading or again.The optimal number of outer arc segments is 3
Or 4, during specific demand, 5,6 or 8 can also be used.
Band is the Ni-based shape memory alloy material of titanium, is with super-elasticity under memory temperature, can change under external force effect
Become its shape, external force restores its shape memory after disappearing.
To reach best surgical effect, shape memory, the top place of all interior segmental arcs are set under the conditions of memory temperature
Diameter of a circle is 1-4mm, and diameter of a circle where the top of all outer arc segments is 10-20mm;Under the conditions of less than memory temperature and
It can be changed by diameter of a circle where the top of segmental arc in external force, it is identical with outer arc size.Meet or exceed memory temperature
When and external force unloading after, the tops of all interior segmental arcs drawn close to band center after where diameter of a circle revert to 1-4mm.
It surprisingly comes off, while better closure effect can be reached to prevent from being closed pressing from both sides, can also be set at the top of each interior segmental arc
Detent projection is put, detent projection is towards closure folder center.
To further enhance closure effect, it is closed folder and may also include the parallel folder consistent with outer arc segment number;It is each parallel
Folder includes two clamps being arranged in parallel;The fixing end of two clamps is connected respectively with the both ends of outer arc segments, on-fixed end position
In in the outer arc segments area defined.
To prevent closing course is favorite from coming off outside, also meshing device can be respectively arranged with two opposite sides of clamp.
Meshing device can be there are many structure type, and main three kinds of structures to be:
1st, meshing device includes at least one pointed tooth of evagination, and the tine locations of pointed tooth and opposite clamp are staggered;Figure 41
In, each clamp includes two pointed tooths, and each 4 pointed tooths for being closed folder are staggered.
2nd, meshing device includes at least one pointed tooth of evagination and the groove of indent, and the pointed tooth of groove and opposite clamp
Quantity shape match, such as groove can be round and smooth slot or V-shaped groove;In Figure 42, each clamp includes 2 points
Tooth and 2 round and smooth slots, pointed tooth are correspondingly arranged with the round and smooth slot on opposite clamp.
3rd, the round and smooth slot of at least one round and smooth protrusion and indent of the meshing device including evagination and the round and smooth slot and phase
Match to the round and smooth number of projection shape of clamp;In Figure 43, each clamp includes a round and smooth protrusion and a round and smooth slot.
Closure is clipped in tissue perforation internal orifice peripheral tissues, has the hyperelastic interior segmental arc for being closed folder or interior segmental arc
It treats anastomosed tissue internal orifice jointly with detent projection and carries out Self-pressurizing agri, while pressurization, the group of the good side of blood circulation
Scar proliferation is knitted, internal orifice is made to heal, achieved the purpose that hurtless measure and does not stay foreign matter in vivo.
Claims (6)
1. a kind of Ni-based marmem tissue closure folder of titanium, is made, feature exists of the Ni-based shape memory alloy material of titanium
In:Including the closure clip main body being made of the band being closed;The band of the closure is by staggered at least three outer arc segments
(91) and the interior segmental arc of identical quantity (92) head and the tail round and smooth connection successively;The closure clip main body is laid out for disk like or bowl-shape cloth
Office;The closure clip main body further includes identical with outer arc segments (91) quantity and one-to-one parallel folder;The parallel folder includes
Two clamps (94) being arranged in parallel;Both ends of the fixing end of described two clamps (94) respectively with outer arc segments (91) are connected,
On-fixed end is located in outer arc segments (91) area defined.
2. the Ni-based marmem tissue closure folder of titanium according to claim 1, it is characterised in that:Described two clamps
(94) opposite side is respectively arranged with meshing device;The meshing device includes at least one pointed tooth (941) of evagination and institute
It states pointed tooth and the tine locations with respect to clamp are staggered or at least one pointed tooth (941) and the groove of indent including evagination
(942) and the quantity shape of the pointed tooth of the groove and opposite clamp matches or at least one round and smooth prominent including evagination
Play the round and smooth groove (944) of (943) and indent and the round and smooth groove and the round and smooth number of projection shape phase with respect to clamp
Matching.
3. the Ni-based marmem tissue closure folder of titanium according to claim 1 or 2, it is characterised in that:The closure
Clip main body, which further includes, is arranged at the top of each interior segmental arc (92) and is directed toward the detent projection (93) for being closed folder center.
4. the Ni-based marmem tissue closure folder of titanium according to claim 3, it is characterised in that:The outer arc segments
(91) quantity is 3,4,5,6 or 8.
5. the Ni-based marmem tissue closure folder of titanium according to claim 4, it is characterised in that:All outer arc segments
(91) diameter of a circle where top is 10-20mm, the top of all interior segmental arcs (92) or top detent projection (93) place circle
A diameter of 1-4mm;The coning angle for being closed clip main body is 120-180 °.
6. the Ni-based marmem tissue closure folder of titanium according to claim 5, it is characterised in that:All outer arc segments
(91) diameter of a circle where top is 12-16mm, the top of all interior segmental arcs (92) or top detent projection (93) place circle
A diameter of 1-3mm;The coning angle of the band of the closure is 160 °.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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PCT/CN2016/111526 WO2017107955A1 (en) | 2015-12-22 | 2016-12-22 | Titanium nickel-based shape memory alloy tissue closing clip, release device, and clip accommodating device |
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CN2015109709107 | 2015-12-22 | ||
CN201510970910 | 2015-12-22 |
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WO2017107955A1 (en) * | 2015-12-22 | 2017-06-29 | 杨西群 | Titanium nickel-based shape memory alloy tissue closing clip, release device, and clip accommodating device |
CN107137119A (en) * | 2017-07-04 | 2017-09-08 | 安瑞医疗器械(杭州)有限公司 | A kind of closing clamp and its method for releasing |
CN107374685B (en) * | 2017-07-09 | 2023-08-15 | 杨西群 | Soft tissue sleeve cutting anastomat based on shape memory alloy |
CN107374691A (en) * | 2017-07-09 | 2017-11-24 | 杨西群 | A kind of Ti-Ni marmem hemorrhoid complicated by anal fistula internal orifice closure folder |
WO2020060730A1 (en) * | 2018-09-18 | 2020-03-26 | Maruho Medical, Inc. | Tissue care device and method of use |
WO2023184056A1 (en) * | 2022-03-28 | 2023-10-05 | 江苏唯德康医疗科技有限公司 | Medical closing clamp |
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CN205831852U (en) * | 2015-12-22 | 2016-12-28 | 杨西群 | Titanium Ni-based marmem tissue closure presss from both sides |
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US6152937A (en) * | 1998-11-06 | 2000-11-28 | St. Jude Medical Cardiovascular Group, Inc. | Medical graft connector and methods of making and installing same |
US6623510B2 (en) * | 2000-12-07 | 2003-09-23 | Integrated Vascular Systems, Inc. | Closure device and methods for making and using them |
US6719777B2 (en) * | 2000-12-07 | 2004-04-13 | Integrated Vascular Systems, Inc. | Closure device and methods for making and using them |
CN202288387U (en) * | 2011-10-26 | 2012-07-04 | 杭州桐庐尖端内窥镜有限公司 | Tissue closing clip capable of absorbing magnesium alloy |
CN204364061U (en) * | 2014-12-24 | 2015-06-03 | 石益海 | The tear-away clamping device of a kind of three-clove style |
CN205019110U (en) * | 2015-08-19 | 2016-02-10 | 上海交通大学 | Take auto -lock structure can internally degrade organize closed clamp |
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CN205831852U (en) * | 2015-12-22 | 2016-12-28 | 杨西群 | Titanium Ni-based marmem tissue closure presss from both sides |
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