CN105769747A - Cosmetic composition for whitening as well as preparation method and application thereof - Google Patents
Cosmetic composition for whitening as well as preparation method and application thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Abstract
The invention discloses a cosmetic composition for whitening. The composition is prepared from the following components: chamomile extract, saussurea involucrate extract, beet root extract, gynostemma pentaphylla extract, glutamic acid, yeast extract, salicylic acid, ascorbyl glucoside, resveratrol, glucosamine, L-asparaginic acid, vitamin E, pitaya enzyme, lecithin, caprylocaproyl macrogolglycerides, 1,2-propylene glycol, isopropyl myristate and deionized water. The cosmetic composition for whitening disclosed by the invention is high in using safety, stability and attractive appearance, has slight skin irritation, does not have any oily feel and can rapidly penetrate into the skin to achieve a whitening effect. The invention also discloses a method for preparing the cosmetic composition for whitening. The method is simple in process steps and low in preparation cost and does not have any special equipment requirement, and the prepared product is high in stability and attractive in appearance.
Description
Technical field
The present invention relates to cosmetic technical field, especially relate to a kind of cosmetic composition for whitening and compound method, application.
Background technology
The most a lot of people especially women are affected by operating pressure, environment and daily life system, cause original ruddy gloss, high resilience, pale soft and smooth skin to become coarse, dark and gloomy, mottle and acne even occur so that self-image is by extreme influence.
Modern theory is thought, the reason that the colour of skin and mottle are formed be by the tyrosine in melanocyte cytochrome under the effect of tryrosinase, generate DOPA, DOPA quinone etc. through peroxidating and ultimately formed excellent melanocyte and two kinds of melanocytes of de-melanocyte, excellent melanocyte darkly, brown, de-melanocyte is red, yellow.Owing to melanocyte kind is different with quantity, and present the different colour of skin, internal and external factor the melanocyte caused is overrun when increasing with skewness, will result in local skin and crosses black and mottle.
In order to pursue healthy pale skin so that the demand of skin-lightening cosmetic is the biggest.Modern skin-lightening cosmetic, by adding whitening active ingredients, generates from suppression melanin and sets about, stop melanic biosynthetic process, so that the minimizing of skin-whitening, facial colour spot, skin color are evenly.The whitening agent type being currently used in cosmetics is more, there are animal proteinum extract, Chinese herbal medicine extract, vitamins, Azelaic Acid class, arbutin etc., animal proteinum body takes thing whitening agent is also worth discussion in safety, Chinese herbal medicine extract whitening agent poor permeability, very difficult skin permeation plays the biology effect of its application, can not reach theoretic whitening effect, and the whitening agent poor stability such as vitamin, arbutin, the most oxidized.
Such as, application publication number CN 101904809 A, Shen Qing Publication day
2010.12.08 Chinese patent disclose a kind of lightening compositions, this compositions contains Cortex Mori extract, camomile extract, Radix Rhodiolae extract, Semen Vitis viniferae extract, Radix Glycyrrhizae extract, chicken Mulberry extract, arbutin, Kojic Acid Dipalmitate, nicotiamide, tetrahydrocurcumin, wetting agent and preservative.This lightening compositions has the disadvantage that the plant extracts such as Cortex Mori extract therein, camomile extract are simply dissolved in polyhydric alcohol solutions by (1), a lot of functional components the most really dissolve and are in dispersity, functional component therein is difficult to arrive deep skin through skin barrier so that said extracted thing is difficult to play real white-skinned face function；(2) melanocyte is formed is a complicated biological process, many factors cause or the result of participation effect jointly, and play whitening function in said composition is only plant extract, arbutin and nicotiamide (vitamin B3) three class materials, only serve antioxidation and the effect of suppression tyrosinase activity, for reducing pigmentation, promoting that desquamation etc. there is no remarkable efficacy, the most each component concertedness is poor, and actual whitening effect is limited；(3) poor stability, needs by adding tetrahydrocurcumin to prevent the oxidation of arbutin and nicotiamide and it needs to by adding preservative to prevent the rotten of product.
Summary of the invention
The present invention is to solve the problems referred to above existing for the lightening compositions of prior art, provide a kind of safety in utilization, stability and outer perception good, little to skin irritation, without greasy feeling, various effective ingredient are reasonably combined, jointly working in coordination with and synergy, energy rapid osmotic skin plays the cosmetic composition for whitening of white-skinned face function.
Present invention also offers a kind of cosmetic composition compound method for whitening, processing step is simple, and to equipment without particular/special requirement, preparation cost is low, and the product stability prepared is good with outer perception.
To achieve these goals, the present invention is by the following technical solutions:
A kind of cosmetic composition for whitening of the present invention, the described cosmetic composition for whitening is made up of the component of following weight/mass percentage composition: 1 ~ 3% camomile extract, 1 ~ 3% Herba Saussureae Involueratae extract, 1 ~ 3% beet root extract, 1 ~ 3% Herb Gynostemmae Pentaphylli extract, 0.1 ~ 0.3% glutamic acid, 1 ~ 3% yeast extract, 0.3 ~ 0.5% salicylic acid, 1 ~ 3% ascorbic acid glucoside, 3 ~ 5% resveratrols, 1 ~ 3% glucamine, 3 ~ 5%L-aspartic acid, 3 ~ 5% vitamin Es, 0.5 ~ 1% Hylocereus undatus ferment, 5 ~ 10% lecithin, 20 ~ 30% Labrasos, 3 ~ 5%1, 2-propylene glycol, 10 ~ 15% isopropyl myristates, balance deionized water.nullFormula is innovated by the present invention，Worked in coordination with by mutual aid、The formula composition of synergy，Wherein camomile extract、Herba Saussureae Involueratae extract、Beet root extract and Herb Gynostemmae Pentaphylli extract (being grease) are collectively forming one and integrate various active composition、There is the plant essence of potent antioxidation，This plant essence Synergistic in the case of not reacting to each other，Skin Cell can be protected from the injury of ultraviolet，Eliminate ultraviolet stimulation that melanin is formed and minimizing because of UV-induced inflammation，Can effectively suppress again the facilitation that radical pair melanocyte is formed，The activity of tyrosinase inhibitor (i.e. salicylic acid in the present invention) can also be maintained，Thus play more powerful whitening effect，Especially containing endothelin antagonist in camomile extract，Endothelin antagonist can be combined by the melanin receptor on cell membrane after entering skin，Make Endothelin ineffective，Thus suppress melanocyte to produce；Containing glycine betaine in beet root extract, moreover it is possible to the salicylic acid in the present invention is played solubilization；Herba Saussureae Involueratae extract energy anti-inflammatory allergy, radioprotective, have and eliminate the facilitation that melanin is formed by various inflammation, sensitizing factor；Containing gypenoside in Herb Gynostemmae Pentaphylli extract, it can activate the liver x receptor in epidermis cell, imitates lipid synthesis, keeps the integrity of skin barrier, improves skin self supporting capacity, reduces the effect that melanocyte is formed by external environment factor；Glutamatergic horny layer softening layer, accelerates cutin pull-up and falls, and provide energy to ripe epidermis cell, accelerate its metabolism, promote the regeneration of epidermis cell, can play the effect accelerated desalination or disappear by mottles various to skin；Yeast extract can effectively help the disappear speckle occurred because of sun damage, environmental injury and cicatrix old and feeble, that accumulate for many years and pigment anomaly, can significantly improve the equilibrium of the colour of skin, improve glossiness and the transparency of skin；Salicylic acid can suppress the activity of tryrosinase, reduces melanocyte and produces；Ascorbic acid glucoside can penetrate in the middle of the horny layer softened by glutamic acid well, prevents the brown patch formed because of Exposure to Sunlight, freckle, and makes that skin is tender has transparent feel；Resveratrol can suppress melanin genesis, and makes skin pigmentation reduce by multiple mechanisms；This composition of glucamine is more to be used on health product, supplements as skeleton nutrition, to promote cell turnover in the present invention, subtracts light color speckle and pox scar, has good effect to increasing skin entirety gloss；ASPARTIC ACID, to help to remove obscure Skin Cell, allows skin substantially recover careful, additionally aids suppression pigment and produces；Vitamin E plays and moistens and the effect of skin protection, can reduce the salicylic acid stimulation to skin, improve comfort of the present invention, it is also possible to accelerates damaged tissues cytothesis, improves cell microcirculation；Hylocereus undatus ferment can anti-lipid peroxidation, prevent generation and the deposition of lipofuscin, oxidisability melanocyte can be made to be reduced to again colourless, subtract light color speckle；Lecithin, Labraso, isopropyl myristate, 1,2-propylene glycol and deionized water water are the big liquid phases of five in nano-emulsion system of the present invention, wherein lecithin forms complexed surfactant (emulsifying agent) with Labraso, isopropyl myristate is oil phase, 1,2-propylene glycol is cosurfactant (co-emulsifier), and the microemulsion region thus formed is maximum, and microemulsion is for having good stability.The present invention is based on the comprehensive consideration on the various factors affecting skin-whitening, from compatibility and the concertedness of each component, suppression tyrosinase activity, external ultraviolet radiation is protected, reduce pigmentation and promote that exfoliation angularly uses omnibearing formula combination, each effective ingredient organic compatibility is formed nanometer micro-emulsion system, without adding any preservative, safety in utilization, stability and outer perception are good, little to skin irritation, without greasy feeling, energy rapid osmotic skin, reasonably combined by various effective ingredient, jointly work in coordination with and synergy, reach skin whitening, facial colour spot reduces, skin color is evenly and rich glossiness effect.
A kind of cosmetic composition compound method for whitening, concretely comprises the following steps:
(1), after weighing each component by above-mentioned weight/mass percentage composition, yeast extract, ascorbic acid glucoside, glucamine, ASPARTIC ACID, Hylocereus undatus ferment are added mix homogeneously in deionized water, obtains aqueous phase.
(2) camomile extract, Herba Saussureae Involueratae extract, beet root extract, Herb Gynostemmae Pentaphylli extract, glutamic acid, salicylic acid, resveratrol and vitamin E are added mix homogeneously in isopropyl myristate, obtain oil phase.
(3) by lecithin, 1,2-PD and Labraso mix homogeneously, emulsifying agent/co-emulsifier mixture is obtained.
(4) by aqueous phase and emulsifying agent/co-emulsifier mixture mixing also sonic oscillation 10 ~ 30min, adding oil phase, sonic oscillation, in transparent and homogeneous emulsion, obtains the cosmetic composition for whitening.Substep mixing is used to make each component form nanometer micro-emulsion system; processing step is simple; to equipment without particular/special requirement; preparation cost is low; make white-skinned face function ingredient solubilization in the droplet of nanometer microemulsion; avoid and the contacting of continuous phase, protect those white-skinned face function compositions susceptible to hydrolysis be not decomposed before reaching site of action or hydrolyze.
As preferably, in step (4), sonic oscillation temperature is 10 ~ 30 DEG C.Control vibration temperature to protect the various heat labile white-skinned face function factors.
The application in cosmetics of a kind of cosmetic composition for whitening.The cosmetic composition for whitening of the present invention can be added on various as in the skin-lightening cosmetic such as facial cream, facial film in the desired amount, and compatibility is good with compatibility, applied range, it is possible to directly use as whitening product.
Therefore, there is advantages that
(1) based on the comprehensive consideration on the various factors affecting skin-whitening, provide a kind of cosmetic composition for whitening, use omnibearing formula combination, each effective ingredient organic compatibility is formed nanometer micro-emulsion system, without adding any preservative, safety in utilization, stability and outer perception are good, little to skin irritation, without greasy feeling, energy rapid osmotic skin, various effective ingredient are reasonably combined, common collaborative and synergy, so that skin whitening, facial colour spot reduces, skin color evenly and is rich in gloss；
(2) by the allotment of the kind to solvent, the white-skinned face function composition organic compatibility of separate sources, different physicochemical property is developed a kind of nanometer micro-emulsion system, nanometer micro-emulsion has good percutaneous penetration and stability, therefore efficiently solves functional component and bioactive substance Transdermal absorption difficulty and the technical problem of poor stability；
(3) providing a kind of cosmetic composition compound method for whitening, processing step is simple, and to equipment without particular/special requirement, preparation cost is low.
Below by human test to further illustrate the technique effect of the present invention.
(1) test object: experimenter is the women at 18 ~ 50 years old age, totally 20, all experimenters test
Position is without affecting the healthy skin of judged result.
(2) method of testing: inside selection experimenter's right arm, skin is Test sites at palm base portion 15cm, inside left arm, at palm base portion 15cm, skin is the blank position of comparison.
The melanin content at position blank with comparison before smearing the present invention first by Mexameter MXl8 the black pigment of skin hematin test instrument determination experiment position, every, each position is surveyed five times, is averaged；Then smear the present invention at subject position, every day smears twice sooner or later；Blank position is left intact.
Experimenter continuously use the present invention one week, two weeks, three weeks, surrounding, five weeks, six weeks, seven weeks and when eight weeks, use Mexameter MXl8 the black pigment of skin hematin test instrument determination test position and the melanin content at the blank position of comparison, same, survey five times, average for every.
(3) test result: the numerical value that statistics subject position records every time, melanocyte statistic is the lowest, then explanation whitening effect is the best.Test result is as follows:
During test, all experimenters test area skin and any discomfort or abnormal phenomena all do not occur.
Detailed description of the invention
Below by detailed description of the invention, the present invention will be further described.
In the present invention, if not refering in particular to, all devices and raw material are all commercially available or the industry is conventional, and the method in following embodiment if no special instructions, is this area conventional method.
Embodiment 1
(1) by 1% camomile extract, 1% Herba Saussureae Involueratae extract, 1% beet root extract, 1% Herb Gynostemmae Pentaphylli extract, 0.1% glutamic acid, 1% yeast extract, 0.3% salicylic acid, 1% ascorbic acid glucoside, 3% resveratrol, 1% glucamine, 3%L-aspartic acid, 3% vitamin E, 0.5% Hylocereus undatus ferment, 5% lecithin, 20% Labraso, 3%1, 2-propylene glycol, 10% isopropyl myristate, after the weight/mass percentage composition of balance deionized water weighs each component, by yeast extract, ascorbic acid glucoside, glucamine, ASPARTIC ACID, Hylocereus undatus ferment adds mix homogeneously in deionized water, obtain aqueous phase；
(2) camomile extract, Herba Saussureae Involueratae extract, beet root extract, Herb Gynostemmae Pentaphylli extract, glutamic acid, salicylic acid, resveratrol and vitamin E are added mix homogeneously in isopropyl myristate, obtain oil phase；
(3) by lecithin, 1,2-PD and Labraso mix homogeneously, emulsifying agent/co-emulsifier mixture is obtained；
(4) being incorporated in sonic oscillation 30min at 10 DEG C by mixed to aqueous phase and emulsifying agent/co-emulsifier mixture, add oil phase, at 10 DEG C, sonic oscillation is in transparent and homogeneous emulsion, obtains the cosmetic composition for whitening.
Embodiment 2
(1) by 3% camomile extract, 3% Herba Saussureae Involueratae extract, 3% beet root extract, 3% Herb Gynostemmae Pentaphylli extract, 0.3% glutamic acid, 3% yeast extract, 0.5% salicylic acid, 3% ascorbic acid glucoside, 5% resveratrol, 3% glucamine, 5%L-aspartic acid, 5% vitamin E, 1% Hylocereus undatus ferment, 10% lecithin, 30% Labraso, 5%1, 2-propylene glycol, 15% isopropyl myristate, after the weight/mass percentage composition of balance deionized water weighs each component, by yeast extract, ascorbic acid glucoside, glucamine, ASPARTIC ACID, Hylocereus undatus ferment adds mix homogeneously in deionized water, obtain aqueous phase；
(2) camomile extract, Herba Saussureae Involueratae extract, beet root extract, Herb Gynostemmae Pentaphylli extract, glutamic acid, salicylic acid, resveratrol and vitamin E are added mix homogeneously in isopropyl myristate, obtain oil phase；
(3) by lecithin, 1,2-PD and Labraso mix homogeneously, emulsifying agent/co-emulsifier mixture is obtained；
(4) being incorporated in sonic oscillation 10min at 30 DEG C by mixed to aqueous phase and emulsifying agent/co-emulsifier mixture, add oil phase, at 10 DEG C, sonic oscillation is in transparent and homogeneous emulsion, obtains the cosmetic composition for whitening.
Embodiment 3
(1) by 2% camomile extract, 2% Herba Saussureae Involueratae extract, 2% beet root extract, 2% Herb Gynostemmae Pentaphylli extract, 0.2% glutamic acid, 2% yeast extract, 0.4% salicylic acid, 2% ascorbic acid glucoside, 4% resveratrol, 2% glucamine, 4%L-aspartic acid, 3.5% vitamin E, 0.6% Hylocereus undatus ferment, 7% lecithin, 25% Labraso, 4%1, 2-propylene glycol, 12% isopropyl myristate, after the weight/mass percentage composition of balance deionized water weighs each component, by yeast extract, ascorbic acid glucoside, glucamine, ASPARTIC ACID, Hylocereus undatus ferment adds mix homogeneously in deionized water, obtain aqueous phase；
(2) camomile extract, Herba Saussureae Involueratae extract, beet root extract, Herb Gynostemmae Pentaphylli extract, glutamic acid, salicylic acid, resveratrol and vitamin E are added mix homogeneously in isopropyl myristate, obtain oil phase；
(3) by lecithin, 1,2-PD and Labraso mix homogeneously, emulsifying agent/co-emulsifier mixture is obtained；
(4) being incorporated in sonic oscillation 20min at 20 DEG C by mixed to aqueous phase and emulsifying agent/co-emulsifier mixture, add oil phase, at 20 DEG C, sonic oscillation is in transparent and homogeneous emulsion, obtains the cosmetic composition for whitening.
The cosmetic composition for whitening of the present invention can be added on various as in the skin-lightening cosmetic such as facial cream, facial film in the desired amount, dissolubility is good with compatibility, applied range, also directly can use as whitening product, type of service does not limits, and all can reach to make skin whitening, facial colour spot minimizing, skin color evenly and rich glossiness effect.
Embodiment described above is the one preferably scheme of the present invention, and the present invention not makees any pro forma restriction, also has other variant and remodeling on the premise of without departing from the technical scheme described in claim.
Claims (4)
1. the cosmetic composition for whitening, it is characterized in that, the described cosmetic composition for whitening is made up of the component of following weight/mass percentage composition: 1 ~ 3% camomile extract, 1 ~ 3% Herba Saussureae Involueratae extract, 1 ~ 3% beet root extract, 1 ~ 3% Herb Gynostemmae Pentaphylli extract, 0.1 ~ 0.3% glutamic acid, 1 ~ 3% yeast extract, 0.3 ~ 0.5% salicylic acid, 1 ~ 3% ascorbic acid glucoside, 3 ~ 5% resveratrols, 1 ~ 3% glucamine, 3 ~ 5%L-aspartic acid, 3 ~ 5% vitamin Es, 0.5 ~ 1% Hylocereus undatus ferment, 5 ~ 10% lecithin, 20 ~ 30% Labrasos, 3 ~ 5%1, 2-propylene glycol, 10 ~ 15% isopropyl myristates, balance deionized water.
2. the cosmetic composition compound method being used for whitening as claimed in claim 1, it is characterized in that, concretely comprise the following steps: after (1) weighs each component by above-mentioned weight/mass percentage composition, yeast extract, ascorbic acid glucoside, glucamine, ASPARTIC ACID, Hylocereus undatus ferment are added mix homogeneously in deionized water, obtains aqueous phase；
(2) camomile extract, Herba Saussureae Involueratae extract, beet root extract, Herb Gynostemmae Pentaphylli extract, glutamic acid, salicylic acid, resveratrol and vitamin E are added mix homogeneously in isopropyl myristate, obtain oil phase；
(3) by lecithin, 1,2-PD and Labraso mix homogeneously, emulsifying agent/co-emulsifier mixture is obtained；
(4) by aqueous phase and emulsifying agent/co-emulsifier mixture mixing also sonic oscillation 10 ~ 30min, adding oil phase, sonic oscillation, in transparent and homogeneous emulsion, obtains the cosmetic composition for whitening.
Cosmetic composition compound method for whitening the most according to claim 2, it is characterised in that in step (4), sonic oscillation temperature is 10 ~ 30 DEG C.
4. one kind is used for the application in cosmetics of the cosmetic composition of whitening as claimed in claim 1.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610206760.7A CN105769747A (en) | 2016-04-05 | 2016-04-05 | Cosmetic composition for whitening as well as preparation method and application thereof |
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| CN201610206760.7A CN105769747A (en) | 2016-04-05 | 2016-04-05 | Cosmetic composition for whitening as well as preparation method and application thereof |
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| CN201610206760.7A Pending CN105769747A (en) | 2016-04-05 | 2016-04-05 | Cosmetic composition for whitening as well as preparation method and application thereof |
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| CN106726703A (en) * | 2016-11-17 | 2017-05-31 | 徐慧婷 | A kind of cosmetics based on Transdermal absorption |
| CN106726741A (en) * | 2016-11-17 | 2017-05-31 | 徐慧婷 | A kind of medical cosmetology skin penetration enhancer containing natural plant essence |
| CN106852884A (en) * | 2017-01-17 | 2017-06-16 | 长沙协浩吉生物工程有限公司 | A kind of compound method of ferment whitening emulsion |
| CN106860375A (en) * | 2017-02-24 | 2017-06-20 | 长沙协浩吉生物工程有限公司 | A kind of compound method of ferment repair latex |
| CN107320381A (en) * | 2017-07-27 | 2017-11-07 | 广州赛莱拉干细胞科技股份有限公司 | A kind of lightening compositions and preparation method thereof |
| CN111728886A (en) * | 2020-07-13 | 2020-10-02 | 植物医生(广东)生物科技有限公司 | Whitening composition and preparation method and application thereof |
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| US11583488B2 (en) | 2020-06-01 | 2023-02-21 | The Procter & Gamble Company | Method of improving penetration of a vitamin B3 compound into skin |
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| CN106726741A (en) * | 2016-11-17 | 2017-05-31 | 徐慧婷 | A kind of medical cosmetology skin penetration enhancer containing natural plant essence |
| CN106726703A (en) * | 2016-11-17 | 2017-05-31 | 徐慧婷 | A kind of cosmetics based on Transdermal absorption |
| CN106852884A (en) * | 2017-01-17 | 2017-06-16 | 长沙协浩吉生物工程有限公司 | A kind of compound method of ferment whitening emulsion |
| CN106860375A (en) * | 2017-02-24 | 2017-06-20 | 长沙协浩吉生物工程有限公司 | A kind of compound method of ferment repair latex |
| US11110049B2 (en) | 2017-06-23 | 2021-09-07 | The Procter & Gamble Company | Composition and method for improving the appearance of skin |
| CN107320381A (en) * | 2017-07-27 | 2017-11-07 | 广州赛莱拉干细胞科技股份有限公司 | A kind of lightening compositions and preparation method thereof |
| US11622963B2 (en) | 2018-07-03 | 2023-04-11 | The Procter & Gamble Company | Method of treating a skin condition |
| US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| US11583488B2 (en) | 2020-06-01 | 2023-02-21 | The Procter & Gamble Company | Method of improving penetration of a vitamin B3 compound into skin |
| US11911498B2 (en) | 2020-06-01 | 2024-02-27 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| CN111728886A (en) * | 2020-07-13 | 2020-10-02 | 植物医生(广东)生物科技有限公司 | Whitening composition and preparation method and application thereof |
| CN113304186A (en) * | 2021-05-26 | 2021-08-27 | 上海橙果生物工程有限公司 | Skin cream capable of relieving joint pain and improving joint vitality as well as preparation method and using method thereof |
| CN113855620A (en) * | 2021-11-24 | 2021-12-31 | 安赛搏(重庆)生物技术有限公司 | Composition containing saussurea involucrate cell culture and preparation method and application thereof |
| CN113855620B (en) * | 2021-11-24 | 2023-08-25 | 安赛搏(重庆)生物技术有限公司 | Composition containing saussurea involucrata cell culture and preparation method and application thereof |
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Application publication date: 20160720 |