A kind of portable 12 lead electrocardiosignal synchronous acquisition device
Technical field
The present invention relates to a kind of harvester of human ecg signal, belong to wired home field of medical device, be specifically
A kind of portable 12 lead electrocardiosignal synchronous acquisition device.
Background technology
Chinese heart disease and cardiovascular patient number are increasing year by year, for many patients, its heart physiological
Parameter can effectively reflect state of an illness state and therapy rehabilitation situation, therefore grasp patient's electrocardiosignal parameter has important meaning in time
Justice.However, since hospital of China (medical treatment) resource is nervous, many gerontal patients and white collar are due to handicapped or work
It is busy, hospital can not be arrived in time and carries out EGC parameter monitoring, miss the good opportunity of heart disease prevention and treatment.
Existing electrocardiosignal parameter acquisition devices largely there are it is expensive, power consumption is high, volume is big, not easily shifted etc.
Shortcoming, can not meet old patient at home (or white collar is in an office) to physical condition carry out self-test, also without
Method carries out real-time monitoring to the electrocardiosignal of rehabilitation;And then there are power consumption requirements for small-sized electrocardiosignal synchronous acquisition device
Height, structure is not reasonable, it is necessary to which external power supply is used, and the control to Current Voltage is not sufficiently stable, the work to equipment
Element is had an impact so as to which the accuracy rate for influencing electrocardiosignal is relatively low, and distortion value is high, and need by small-sized display into
Display of the row to electric signal, therefore using trouble, and cannot possess analysis and preserve the function of data, inadequate hommization, therefore
It is difficult to promote the use of on a large scale.
The content of the invention
It is an object of the invention to there is the shortcomings of not portable and volume is big for current domestic electrocardiographicoscilloscope oscilloscope, there is provided a kind of
Portable 12 lead electrocardiosignal synchronous acquisition device, electrode holder can be easily clipped on measured's body by it, in real time
Accurately 12 cardiac diagnosis lead figure waveforms are included on the Intelligent mobile equipment client software of user, client software is simultaneously
Equipped with ecg analysis and function is preserved, contributes to cardiovascular patient to be guarded at home to EGC parameter, while be doctor
Diagnosis provide a reliable material.
To reach above-mentioned purpose, the present invention adopts the following technical scheme that:A kind of portable 12 lead electrocardiosignal is synchronous
Harvester includes:Housing, conducting wire, several electrodes for lead body, the switch key being placed on housing, be placed in shell
Modular converter, MCU module, wireless data transceiver module, battery pack and the data receiver display in internal portion,
Wherein:The input terminal of the front end connection electrode of conducting wire, the rear end connection modular converter of conducting wire, modular converter
Communication ends and control terminal are connected with the communication ends and control terminal of MCU module, the serial ports of MCU module and wireless data transceiver module
Input terminal connects, and battery pack connecting valve post-positioned press keys are in being modular converter, MCU module and wireless data transceiver module in housing
Power supply is provided;Wireless data transceiver module wireless connection data receives display;
The modular converter is the ADS1298 modular converters of 24 high-precision A/D, and ADS1298 modular converters set ADS1298
The Differential Input mouth of conversion chip, eight passages, the Differential Input mouth of eight passages are used for the electrocardio of input front end electrode collection
Signal, EMI filter circuit, 8 road programmable gain amplifiers, right leg drive amplifying circuit and prestige built in ADS1298 conversion chips
Your inferior centra electric terminals and spi bus configure acquisition channel, spi bus configuration acquisition channel connection MCU module;
The ADS1298 modular converters further include ECG signal processing circuit, the ECG signal processing circuit
Including first resistor, second resistance, No.1 clamper limiter diode, No. two clamper limiter diodes, No.1 capacitance and No. two electricity
Hold, one end of first resistor is connected with the output terminal of electrode, the other end of first resistor and one end of second resistance and No.1 electricity
One end of appearance is connected, the other end of second resistance one end with No. two capacitances, one end of No.1 clamper limiter diode, two respectively
One end of number clamper limiter diode is connected with the input terminal of a passage of ADS1298 conversion chips, No.1 capacitance and No. two
The other end of capacitance connects AGND ends, another termination AVDD ends of No.1 clamper limiter diode, No. two two poles of clamper amplitude limit respectively
Another termination AVSS ends of pipe.
Preferably, the MCU module includes STM32F103 microcontrollers, chip crystal oscillating circuit, reset circuit, is
The electric source filter circuit and GPIO port, the SPI of connection STM32F103 microcontrollers connect respectively that STM32F103 microcontrollers are powered
Mouth and USART serial ports.
Preferably, the battery pack includes:Lithium battery, lithium battery charging module, lithium battery voltage modular converter, battery electricity
Measurement module, lithium battery charging module are connected with lithium battery voltage modular converter, battery capacity measurement module and MCU module phase
Even, lithium battery voltage modular converter respectively with ADS1298 modular converters, battery capacity measurement module, MCU module and wireless data
Transceiver module is connected.
Preferably, the lithium battery voltage modular converter includes boost converter chips, the 4th filter capacitor, power electricity
Sense, the 5th filter capacitor, the 6th filter capacitor, the 7th filter capacitor,
Boost converter chips connect one end of lithium battery anode, one end of power inductance and the 4th filter capacitor, the 4th filter
One termination GND ends of ripple capacitance, the pin connection GND ends of boost converter chips, one of boost converter chips draw
Foot connects the other end of power inductance, and a pin of boost converter chips connects the 6th filter capacitor and the 7th filter capacitor
One end, another termination GND ends of the 6th filter capacitor and the 7th filter capacitor, the pin connection of boost converter chips
One end of 5th filter capacitor, another termination GND ends of the 5th filter capacitor, the pin connection of boost converter chips
GND ends, the anode of the pin connection lithium battery of boost converter chips.
Preferably, the lithium battery voltage modular converter has further included voltage conversion chip, for respectively by lithium battery
Pressure is converted into 3.3V, 2.5V, -2.5V, and 2.5V and -2.5V provide bipolar voltage for ADS1298 modular converters, 3.3V while again
Power for MCU module and wireless data transceiver module.
Preferably, the battery capacity measurement module includes the second current-limiting resistance, the second filter capacitor, two pole of No.1
Pipe, switch key, No. two diodes, lithium battery socket, the 3rd filter capacitor, the 4th resistance, management of charging and discharging chip, first are filled
Indication LED of discharging lamp, the second discharge and recharge indication LED lamp,
Management of charging and discharging chip connection USB5V ends, a pin of management of charging and discharging chip connect the one of No. two diodes
End and one end of lithium battery socket, the pin connection GND ends of management of charging and discharging chip, a termination second of two current-limiting resistances
One end of filter capacitor, another termination the first discharge and recharge indication LED lamp of two current-limiting resistances and the second discharge and recharge indication LED lamp
One end, another termination GND ends of the second filter capacitor, a termination USB5V ends of No.1 diode, the other end of No.1 diode
Connect one end of switch key and No. two diodes, another termination VCC ends of switch key, a termination charge and discharge of the 3rd filter capacitor
A pin, one end of lithium battery socket and one end of No. two diodes of electric managing chip, a termination charge and discharge of the 4th resistance
One pin of electric managing chip, another termination GND ends of the 4th resistance, another termination of the first discharge and recharge indication LED lamp are filled
One pin of electric discharge managing chip, a pin of another termination management of charging and discharging chip of the second discharge and recharge indication LED lamp.
Preferably, the wireless data transceiver module is serial ports Wi-Fi module or serial ports bluetooth module, the data receiver
Display is Intelligent mobile equipment, and the Intelligent mobile equipment is smart mobile phone or tablet computer, laptop.
Preferably, client modules are installed, the client modules include data and connect in the Intelligent mobile equipment
Receive unit, data display unit, data analysis unit and data storage cell, data receipt unit, data display unit, data
Analytic unit is mutually connected with data storage cell, and serial ports bluetooth module is communicated to connect with MCU module, data receipt unit and string
Mouth bluetooth module is connected by bluetooth communication,
Data receipt unit is used for the data transmitted by receiving radio data transceiver module;
The screen that data display unit is called Intelligent mobile equipment for docking received data is shown;
Data analysis unit is used to dock the received intelligent pathological analysis of data progress, will letter after being drawn a conclusion by analysis
Cease data returned data display unit;
Data storage cell is stored for docking received data.
Preferably, the serial ports bluetooth module include serial ports Bluetooth chip, the 3rd capacitance, 3rd resistor, touch key,
Current-limiting resistance, bluetooth indicator light and the first filter capacitor,
Wherein:The pin connection TXD ends of serial ports Bluetooth chip, another pin connects RXD ends, another pin connects
3.3V ends, another pin meet GND ends, a pin of a termination serial ports Bluetooth chip of the 3rd capacitance, another termination GND
End, a pin of a termination serial ports Bluetooth chip of 3rd resistor, one end of another termination touch key of 3rd resistor, gently
Another termination 3.3V ends of touch of key-press, current-limiting resistance one termination serial ports Bluetooth chip a pin, current-limiting resistance it is another
One end of termination bluetooth indicator light, another termination GND ends of bluetooth indicator light, a termination GND ends of the first filter capacitor, first
Another termination 3.3V ends of filter capacitor, the serial ports Bluetooth chip are 4.0 chip of HM-11 bluetooths, the bluetooth indicator light and
Touch key is arranged in housing outer surface, and 4.0 chip of HM-11 bluetooths is mutually gone here and there with bluetooth indicator light and bluetooth touch key
Connection, the RXD pins of 4.0 chip of HM-11 bluetooths are connected to the USART serial ports of MCU module in succession.
Preferably, the lithium battery charging module selects TP4057 chips, and the battery capacity measurement module is selected
LTC2941 chips are simultaneously accessed and configured to it with I2C interface.
Compared with prior art, the present invention has following remarkable advantage:
A kind of portable 12 lead electrocardiosignal synchronous acquisition device of the present invention can as intelligent domestic Medical Devices,
Using two-ply PCB circuit board mask-making technology, it is long and it is wide be respectively that 9mm and 6mm make it that the device volume is small, easy to carry, work(
Consume that relatively low, accuracy is high, meanwhile, in the optimization structure and power consumption control of potential circuit so that device power supply can use normal
The compact lithium cell seen, and can intuitively visual be charged by mobile power (charger baby) to the device, used communication party
Formula is serial communication and SPI communication, selects wireless wifi or bluetooth connection, can be shown on Intelligent mobile equipment in real time
Waveform, and anomaly analysis can be carried out to waveform, and data can be preserved and recorded on Intelligent mobile equipment, easy to for user
Observation uses, and AD conversion chip data processing speed is fast used by the device, its sample frequency is 250SPS~32kSPS, and ten
The display of two ecg wave forms is the synchronous reflection in real time of electrocardiosignal.
In conclusion the system hardware structure of the present invention is simple, small volume, power consumption is relatively low, precision is higher, product development
Cycle is short, easy to promote the use of, and is a convenience, practicality, reliable domestic intelligent electrocardiosignal synchronous acquisition device.
Brief description of the drawings
Fig. 1 is a kind of structure diagram of overall system of the present invention.
Fig. 2 is the ECG signal processing circuit figure of the harvester of the present invention.
Fig. 3 is the lithium battery voltage 5V booster circuit figures in the present invention.
Fig. 4 is the circuit diagram of the serial ports bluetooth module in the present invention.
Fig. 5 is the circuit diagram of the lithium battery charging module in the present invention.
Embodiment
The embodiment of the present invention is described further below in conjunction with the accompanying drawings.
Embodiment 1:As shown in Figure 1:A kind of portable 12 lead electrocardiosignal synchronous acquisition device, including:Housing, lead
On line, several electrodes for lead body, the switch key 404 being placed on housing, the modular converter for being placed in enclosure interior,
MCU module, wireless data transceiver module, battery pack and data receiver display,
Wherein:The input terminal of the front end connection electrode of conducting wire, the rear end connection modular converter of conducting wire, modular converter
Communication ends and control terminal are connected with the communication ends and control terminal of MCU module, the serial ports of MCU module and wireless data transceiver module
Input terminal connects, and it is modular converter, MCU module and wireless data transceiving that battery pack connecting valve button 404, which is placed in housing,
Module provides power supply;Wireless data transceiver module wireless connection data receives display;
The conducting wire shields conducting wire, the every front end connection electrode with shielding conducting wire, rear end connection for ten bands
The input terminal of modular converter, during use:Electrode is pressed from both sides by limbs be connected in measured respectively with 10 band shielding conducting wires
Left finesse, right finesse, left foot wrist, right crus of diaphragm wrist and the chest of body, can measure the heart life that can react measured in more detail
12 cardiac diagnosis lead figures of parameter are managed, the electrocardiosignal inputted by the electrode of measured is gathered by modular converter,
The modular converter is the ADS1298 modular converters of 24 high-precision A/D, and ADS1298 modular converters set ADS1298
The Differential Input mouth of conversion chip, eight passages, the Differential Input mouth of eight passages are used for the electrocardio of input front end electrode collection
Signal, EMI filter circuit, 8 road programmable gain amplifiers, right leg drive amplifying circuit and prestige built in ADS1298 conversion chips
Your inferior centra electric terminals and spi bus configure acquisition channel, spi bus configuration acquisition channel connection MCU module;ADS1298 is changed
Chip is compared with the A/D conversion circuits that common analog device is built, its acquisition precision higher, filter effect is more preferable, and function is more
Add comprehensively, volume smaller, so that reach portable, accurately effect,
Wherein:As shown in Fig. 2, the ADS1298 modular converters further include ECG signal processing circuit, the electrocardio
Signal pre-processing circuit includes 103, No. two first resistor 101, second resistance 102, No.1 clamper limiter diode clamper amplitude limits
Diode 104, No.1 capacitance 105 and No. two capacitances 106, one end of first resistor 101 are connected with the output terminal of electrode, the first electricity
The other end of resistance 101 is connected with one end of second resistance 102 and one end of No.1 capacitance 105, the other end point of second resistance 102
One end of one end, No.1 clamper limiter diode 103 not with No. two capacitances, No. two clamper limiter diodes 104 one end and
The input terminal of one passage of ADS1298 conversion chips is connected, and the other end of No.1 capacitance 105 and No. two capacitances 106 connects respectively
AGND ends, another termination AVDD ends of No.1 clamper limiter diode 103, another termination of No. two clamper limiter diodes 104
AVSS ends, pretreatment circuit can prevent the introducing of external noise, prevent the too high or too low of signal voltage, help accurately to adopt
Collect the voltage signal of human body, prevent distorted signals, so that the accurate and stability to the electrocardiosignal of collection is improved,
Electrocardiosignal is changed after the ADS1298 modular converters collection of 24 high-precision A/D, transformed electrocardio
Signal configures acquisition channel by spi bus as output and is transmitted to MCU module, and MCU module carries out displacement fractionation to electrocardiogram (ECG) data
Then data are sent data to wireless data transceiver module by serial port, wireless data transceiver module is by data
Transmission to data receiver display carries out the display to the electrocardiosignal of implementation, realizes the heart of the measured of portable stabilization
The real-time synchronization monitoring display of 12 cardiac diagnosis lead figures of physiological parameter.
Embodiment 2:On the basis of embodiment 1, the MCU module includes STM32F103 microcontrollers, chip crystal oscillator electricity
Road, reset circuit, be the electric source filter circuit of STM32F103 microcontrollers power supply and connect STM32F103 microcontrollers respectively
GPIO port, SPI interface and USART serial ports, using these interfaces carry out after communication facilitates upgrading to device, program and
The extension of additional function is provided device, improves the use of device by face and the service life of long failure, chip crystal oscillator therein
Circuit, reset circuit, electric source filter circuit is the necessary circuits of microcontroller work, which ensure that the normal operation of microcontroller, from
And make it that the stability of device in operation has and ensure, STM32F103 carries out electrocardiogram (ECG) data displacement and splits and then data
Send, Android client software carries out displacement integration to the electrocardiogram (ECG) data of reception, therefore ensure that slave computer main control MCU passes
The original electrocardiographicdigital data come are accurate, while carry out 3 rank Butterworth low pass ripples to electrocardiosignal, remove external disturbance and make an uproar
Sound, so as to improve the precision of the electrocardiogram (ECG) data of collection so that monitoring result is authentic and valid;
The battery pack includes:Lithium battery, lithium battery charging module, lithium battery voltage modular converter, battery capacity measurement
Module, lithium battery charging module are connected with lithium battery voltage modular converter, battery capacity measurement module and STM32F103 master controls
MCU module is connected, lithium battery voltage modular converter respectively with ADS1298 modular converters, battery capacity measurement module,
STM32F103 main control MCU modules are connected with serial ports bluetooth module, the battery charging and discharging managing chip choosing in lithium battery charging module
With TP4057 chips, it include charging current monitor, recharge automatically, two instruction chargings terminate and input voltage access
Status pin;Its working range is very suitable for single-unit lithium ion battery, and accurately coulomb meter is responsible for flowing through inside it
The electric current of a detection resistance device between battery positive and load carries out integral and calculating, and measurement electric charge is stored in inside it
In register, it is accessed and configured with I2C interface.
As shown in Figure 3:Lithium battery voltage modular converter includes boost converter chips 201, the 4th filter capacitor 202, work(
Rate inductance 203, the 5th filter capacitor 204, the 6th filter capacitor 205, the 7th filter capacitor 206,
No. 5 pins of boost converter chips 201 connect lithium battery anode, one end of power inductance 203 and the 4th filtered electrical
Hold 202 one end, a termination GND ends of the 4th filter capacitor 202, No. 4 pins of boost converter chips 201 connect GND ends, rise
No. 3 pins of pressure converter chip 201 connect the other end of power inductance 203, and No. 2 pins of boost converter chips 201 connect
One end of six filter capacitors 205 and the 7th filter capacitor 206, No. 10 pins of boost converter chips 201, the 6th filter capacitor
205 and the 7th filter capacitor 206 another termination GND ends, No. 1 pin of boost converter chips 201 connects the 5th filter capacitor
204 one end, another termination GND ends of the 5th filter capacitor 204, No. 9 pins of boost converter chips 201 connect GND ends, rise
No. 6 pins, No. 7 pins, No. 8 pins of pressure converter chip 201 connect the anode of lithium battery.Lithium battery voltage modular converter can be with
Lithium battery voltage is promoted to 5V, so as to more easily give modular converter, MCU module, wireless data transceiver module power supply, is kept away
Exempt from interference of the change to whole device of lithium battery voltage, not only meet the use specification to the lithium battery of small portable, but also
Stable output voltage is capable of providing, is reduced as caused by the factors such as circuit voltage to negative shadow caused by electrocardiosignal
Sound, so as to ensure the accurate and stability of electrocardiosignal so that the result of monitoring and display is synchronous and accurate;
The lithium battery voltage modular converter has further included TPS73233 chips, TPS73225 chips and TPS60403 cores
Piece, for lithium battery voltage to be converted into 3.3V, 2.5V, -2.5V respectively, TPS73225 chips and TPS60403 chips are
ADS1298 modular converters provide bipolar voltage, while TPS73233 chips supply for MCU module and wireless data transceiver module
Electricity,
As shown in Figure 5:The battery capacity measurement module include the second current-limiting resistance 401, the second filter capacitor 402,
No.1 diode 403,404, No. two diodes 405 of switch key, lithium battery socket 406, the electricity of the 3rd filter capacitor the 407, the 4th
Resistance 408, management of charging and discharging chip 409, the first discharge and recharge indication LED lamp 410, the second discharge and recharge indication LED lamp 411,
No. 4 pins of management of charging and discharging chip 409 connect USB5V ends, and No. 3 pins of management of charging and discharging chip 409 connect No. two
One end of diode 405 and one end of lithium battery socket 406, No. 2 pins of management of charging and discharging chip 409 connect GND ends, two current limlitings
One end of one the second filter capacitor 402 of termination of resistance 401, another termination the first discharge and recharge indication LED of two current-limiting resistances 401
One end of 410 and second discharge and recharge indication LED lamp 411 of lamp, another termination GND ends of the second filter capacitor 402, No.1 diode
A 403 termination USB5V ends, one end of another the termination switch key 404 and No. two diodes 405 of No.1 diode 403, is opened
Another termination VCC ends of close button 404, No. 3 pins, lithiums of a termination management of charging and discharging chip 409 of the 3rd filter capacitor 407
One end of battery socket and one end of No. two diodes 405, No. 6 of a termination management of charging and discharging chip 409 of the 4th resistance 408
Pin, another termination GND ends of the 4th resistance 408, another termination management of charging and discharging core of the first discharge and recharge indication LED lamp 410
No. 1 pin of piece 409, No. 5 pins of another termination management of charging and discharging chip 409 of the second discharge and recharge indication LED lamp 411.
Lithium battery charge management module can charge battery pack, while can intuitively observe and charge or
Full of two states, the use of lithium battery also makes the device can be repeated several times use, and makes device more convenient and hommization.
The wireless data transceiver module serial ports bluetooth module, the data receiver display are Intelligent mobile equipment such as intelligence
Can mobile phone, client modules are installed, it is single that the client modules include data receipt unit, data display in smart mobile phone
Member, data analysis unit and data storage cell, data receipt unit, data display unit, data analysis unit and data are deposited
Storage unit is mutually connected, and serial ports bluetooth module is communicated to connect with MCU module, and data receipt unit passes through indigo plant with serial ports bluetooth module
Tooth communication connection,
Data receipt unit is used for the data transmitted by receiving radio data transceiver module;
The screen that data display unit is called smart mobile phone for docking received data is shown;
Data analysis unit is used to dock the received intelligent pathological analysis of data progress, will letter after being drawn a conclusion by analysis
Cease data returned data display unit;
Data storage cell is stored for docking received data.
As shown in Figure 4:The serial ports bluetooth module includes serial ports Bluetooth chip 301, the 3rd capacitance 302,3rd resistor
303rd, touch key 304, current-limiting resistance 305,306 and first filter capacitor 307 of bluetooth indicator light,
Wherein:No. 2 pins of serial ports Bluetooth chip 301 connect TXD ends, No. 4 pins connect RXD ends, No. 9 pins connect 3.3V ends,
No. 12 pins connect GND ends, No. 16 pins of a termination serial ports Bluetooth chip 301 of the 3rd capacitance 302, another termination GND ends, the
No. 16 pins of one termination serial ports Bluetooth chip 301 of three resistance 303, another termination touch key 304 of 3rd resistor 303
One end, another termination 3.3V ends of touch key 304, No. 15 of a termination serial ports Bluetooth chip 301 of current-limiting resistance 305 are drawn
Foot, one end of another termination bluetooth indicator light 306 of current-limiting resistance 305, another termination GND ends of bluetooth indicator light 306, first
One termination GND ends of filter capacitor 307, another termination 3.3V ends of the first filter capacitor 307, the serial ports Bluetooth chip are
4.0 chip of HM-11 bluetooths, the bluetooth indicator light and touch key are arranged in housing outer surface, 4.0 chip of HM-11 bluetooths
It is serially connected with bluetooth indicator light and bluetooth touch key, the RXD pins of 4.0 chip of HM-11 bluetooths are connected to MCU module in succession
USART serial ports.It can be seen that above-mentioned connection structure simplifies serial ports bluetooth module circuit, the most basic of serial ports Bluetooth circuit is remained
Function, simplifies the circuit of whole system in the quality for ensureing transmission, saves the electricity of battery pack, improve the easy of the present apparatus
With property and durability, also reduce the large capacity demand to battery apparatus, so as to meet it is compact easily design so that into
One step significantly highlights the characteristics of present apparatus and advantage.
Therefore, the ecg signal data of the measured collected by preceding termination electrode eventually through serial ports bluetooth module send to
On the smart mobile phone of measured, the directly perceived, display of real-time synchronization is carried out in client modules, and believe by the electrocardio of measured
Number information, draws corresponding analysis result according to relevant scientific analysis, analysis result feedback is shown on client modules,
And the ecg signal data information of this measured can be recorded by client modules, realize intelligent management, improve user
Interactive experience, fundamentally effectively helped user.
Embodiment 3:Difference lies in serial ports bluetooth module is substituted for serial ports Wi-Fi module, intelligent mobile with embodiment 2
Equipment is tablet computer.Tablet computer can show real-time waveform according to the ecg information of measured, and waveform can carry out different
Often analysis, can also be stored in mobile phone EMS memory card, and AD conversion chip data processing speed is fast used by the device, it samples frequency
Rate is 250SPS~32kSPS, and the display of 12 ecg wave forms is the real-time reflection of electrocardiosignal.
It should be appreciated that the above-mentioned embodiment of the present invention is used only for exemplary illustration or explains the present invention's
Principle, without being construed as limiting the invention.Therefore, that is done without departing from the spirit and scope of the present invention is any
Modification, equivalent substitution, improvement etc., should all be included in the protection scope of the present invention.In addition, appended claims purport of the present invention
Covering the whole changes fallen into scope and border or this scope and the equivalents on border and repairing
Change example.