CN105615869A - 12-lead electrocardiograph signal acquisition device - Google Patents
12-lead electrocardiograph signal acquisition device Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
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Abstract
The invention relates to a 12-lead electrocardiograph signal acquisition device. The device comprises nine electrocardiograph electrode signal acquisition channels, an analog switch, a buffering and filtering circuit, a fully-differential amplifying circuit, an analog-to-digital conversion circuit, a Wilson center reference circuit and a right leg driving circuit, wherein the nine electrocardiograph electrode signal acquisition channels are connected with the input end of the analog switch; the output end of the analog switch, the buffering and filtering circuit, the fully-differential amplifying circuit and the analog-to-digital conversion circuit are connected in sequence; each of the electrocardiograph electrode signal acquisition channels comprises an input protection circuit, a front-end gain amplifying circuit and a low-pass filtering circuit in sequence; the Wilson center reference circuit is used for acquiring input voltages of corresponding low-pass filtering circuits in a left-arm acquisition channel, a right-arm acquisition channel and a left-leg acquisition channel, processing the three acquired input voltages, and outputting a Wilson center potential to the analog switch and the right-leg driving circuit. The 12-lead electrocardiograph signal acquisition device provided by the invention is simple in structure, and is relatively low in cost.
Description
Technical field
The present invention relates to a kind of signal pickup assembly, particularly relate to a kind of 12 and lead electrocardiogram signal acquisition device.
Background technology
It is known that bioelectrical signals detection all carries out with when there is patient's polarizing voltage in strong ambient interferences, due to the impact of strong jamming (particularly Hz noise), it is necessary to adopt instrument amplifier. And bioelectrical signals is all very faint, generally require more than amplification hundreds times. As electrode and contact human skin, there is polarizing voltage, therefore the first order gain of base amplifier is all smaller, it is necessary to utilize second level amplifier to be amplified after isolating polarizing voltage with resistance-capacitance circuit. Owing to there is time constant circuit, therefore relatively larger in patient's polarizing voltage, when causing first order output saturated, electric capacity can be charged, assume now patient status stable (the upper polarizing voltage of patient reaches smaller normal value), then to need the time grown very much to discharge complete for the electric charge on capacitance, cannot be carried out ECG signal and gather during this.
Therefore, traditional exchange amplification has the disadvantage that dynamic range of signals is little, and circuit is complicated and noise is big, and amplifier is saturated with baseline restorer slowly (baseline drift), capacity of resisting disturbance is not good, lossing signal flip-flop and lose the problem of AC signal close to direct current signal.
For solving problem above, the industry many employings DC amplification circuit device with instrument amplifier, but, traditional DC amplification circuit device but still have the disadvantage that 1. circuit are still more complicated, and amplifying element is numerous, unfavorable for controlling system noise; 2. suppress the ability of common mode disturbances; 3. the signal after the instrument amplifier adopted is all single-ended signal, cannot get rid of for the common mode disturbances on holding wire after Space Coupling to instrument amplifier; 4. with high costs, instrument amplifier prevailing price is high, and according to the instrument amplifier that three amplifiers are built, cost is high on the one hand, and another aspect common mode rejection ratio is limited to build-out resistor precision and is difficult to improve.
In sum, adopt traditional DC amplification circuit device, it is difficult to avoid the problem that cost is high and common mode rejection ratio is undesirable simultaneously.
Summary of the invention
In view of this, the present invention provides a kind of low cost and high performance 12 to lead electrocardiogram signal acquisition device.
The technical solution used in the present invention: a kind of 12 lead electrocardiogram signal acquisition device, it includes nine electrocardioelectrode signal sampling channels, an analog switch, a buffering and filter circuit, a fully differential amplifying circuit, an analog to digital conversion circuit, Wilson's center reference circuit and a driven-right-leg circuit; Nine electrocardioelectrode signal sampling channels include a left arm acquisition channel, a right arm acquisition channel, a left lower limb acquisition channel and the first to the 6th shirtfront acquisition channel; Nine electrocardioelectrode signal sampling channels are all connected with the input of described analog switch; The outfan of described analog switch, described buffering are sequentially connected with filter circuit, described fully differential amplifying circuit and analog-digital conversion circuit as described; Each electrocardioelectrode signal sampling channel all includes the input protection circuit, a preamplifier gain amplifying circuit and the low-pass filter circuit that are sequentially connected with; Described Wilson's center reference circuit gathers the input voltage of each low-pass filter circuit corresponding in described left arm acquisition channel, described right arm acquisition channel and described left lower limb acquisition channel, and exports a Wilson's central potential after three input voltages gathered are processed to described analog switch and described driven-right-leg circuit.
Compared to prior art, provided by the invention 12 lead employing fully differential amplifying circuit in electrocardiogram signal acquisition device, from without adopting multiple amplifier in circuit, save board design space, circuit structure is simple, less costly, also ensure that noise and common mode rejection ratio all can reach higher index simultaneously, and baseline is sufficiently stable, signal input dynamic range is big, it is not easy to satisfy, thus reliability is high, moreover it is possible to support that perfect PACE (pacemaker impulse) detects.
Accompanying drawing explanation
12 electrical block diagrams leading electrocardiogram signal acquisition device that Fig. 1 provides for embodiment of the present invention.
Fig. 2 is the electrical block diagram that the Wilson's center reference circuit in electrocardiogram signal acquisition device is led in 12 in Fig. 1.
Main element symbol description: 100,12 lead electrocardiogram signal acquisition device; 10, electrocardioelectrode signal sampling channel; 101, input protection circuit; 102, preamplifier gain amplifying circuit; 103, low-pass filter circuit, 11, left arm acquisition channel, 12, right arm acquisition channel; 13; left lower limb acquisition channel, 14��19 the first to the 6th shirtfront acquisition channels, 20, analog switch; 30, buffering and filter circuit; 40, fully differential amplifying circuit, 41, wave filter, 50, analog to digital conversion circuit; 60, Wilson's center reference circuit, 70, driven-right-leg circuit
Detailed description of the invention
Below in conjunction with accompanying drawing, principles of the invention and feature being described, example is served only for explaining the present invention, is not intended to limit the scope of the present invention.
Refer to Fig. 1-2, the one 12 provided for embodiment of the present invention leads electrocardiogram signal acquisition device 100, and it includes nine electrocardioelectrode signal sampling channels 10, analog switch 20, buffering and filter circuit 30, fully differential amplifying circuit 40, analog to digital conversion circuit 50, Wilson's center reference circuit 60 and a driven-right-leg circuit 70.
Described electrocardioelectrode signal sampling channel 10 includes left arm acquisition channel 11, right arm acquisition channel 12, left lower limb acquisition channel 13 and first to a 6th shirtfront acquisition channel 14��19, and each described electrocardioelectrode signal sampling channel 10 all includes input protection circuit 101, preamplifier gain amplifying circuit 102 and the low-pass filter circuit 103 being sequentially connected with.
Described input protection circuit 101 is made up of gas-discharge tube, current-limiting resistance, filter capacitor, clamper double diode; input high energy signals is limited to protect late-class circuit by this circuit; in acquiring biological electric signals, it is generally used for anti-defibrillation, anti-electric knife, ESD protection purpose.
Described preamplifier gain amplifying circuit 102 includes one first amplifier P1, one first resistance R1 and one second resistance R2; The positive input of described first amplifier P1 is connected with the outfan of described input protection circuit 101; the outfan of described first amplifier P1 is connected with one end of described first resistance R1; the negative input of described first amplifier P1 is connected with the other end of described first resistance R1 and is jointly connected to a reference potential through described second resistance R2, and the value of described reference potential is based on circuit structure design and determines. 102 impedance transformation functions of described preamplifier gain amplifying circuit, typical structure is the buffer of low maladjustment voltage, low offset current, low-noise operational amplifier composition, high input impedance is provided for input signal, provides low output impedance for late-class circuit, when needing gain to amplify, this circuit is the amplifying circuit of amplifier and gain resistor composition, for benchmark, input signal is carried out preposition amplification with reference potential simultaneously.
Described low-pass filter circuit 103 includes one the 3rd resistance R3 and one first electric capacity C1; One end that described 3rd resistance R3 is connected between outfan and the input of described analog switch 20 of described first amplifier P1 and described 3rd resistance R3 is connected with the input of described analog switch 20 is through described first electric capacity C1 ground connection. Described low-pass filter circuit 103 is main to be filtered prime output signal, and including prime interference and noise, filtered signal is input to rear class analog switch 20.
Described analog switch 20 includes nine electrocardiosignal inputs, a reference signal input, a forward outfan, a negative sense outfan, one first outfan and one second outfan, nine electrocardiosignal inputs are connected with nine acquisition channels of described electrocardioelectrode signal sampling channel 10 respectively. described analog switch 20 controls switching by MCU, it is configured to 8 and selects 1 gated mode, select input 2 tunnel electrocardiosignaies every time, respectively obtain 8 groups of pre-differential signals of electrocardio, the output signal of the 8 groups of signals of telecommunication being sequentially output respectively six groups of front acquisition channels (first to the 6th) respectively with Wilson's reference center current potential, left arm acquisition channel output signal and right arm acquisition channel output signal, left lower limb acquisition channel output signal and right arm acquisition channel output signal, namely (V1 ', WCT), (V2 ', WCT), (V3 ', WCT), (V4 ', WCT), (V5 ', WCT), (V6 ', WCT), (LA ', RA '), (LL ', RA ').
Described buffering and filter circuit 30 include one first amplifier P2, one second amplifier P3 and one second electric capacity C2; The positive input of described first amplifier P2 is connected with the first outfan of described analog switch 20, and the negative input of described first amplifier P2 is connected with its outfan and is commonly connected to one end of described second electric capacity C2 and forms an outfan of described buffering and filter circuit 30; The positive input of described second amplifier P3 is connected with the second outfan of described analog switch 20, and the P3 negative input of described second amplifier is connected with its outfan and is commonly connected to the other end of described second electric capacity C2 and forms another outfan of described buffering and filter circuit 30. The output signal of analog switch 20 is provided impedance transformation and filters switching noise by described buffering and filter circuit 30.
Described fully differential amplifying circuit 40 includes a difference amplifier P4, the 4th to the 7th resistance R4��R7 and a wave filter 41; The positive input of described difference amplifier P4 is connected with an outfan of filter circuit 30 with described buffering by described 4th resistance R4, and described 5th resistance R5 is connected between positive input and the negative sense outfan of described difference amplifier P4; The negative input of described difference amplifier P4 is connected with another outfan of filter circuit 30 with described buffering by described 6th resistance R6, and described 7th resistance R7 is connected between negative input and the forward outfan of described difference amplifier P4; Described wave filter 41 is connected with forward outfan and the negative sense outfan of described difference amplifier P4. Described fully differential amplifying circuit 40 adopts the high-precision gain resistor in single-chip integration fully-differential amplifier P4 and periphery to constitute, integrated fully-differential amplifier has high common mode inhibition capacity, low maladjustment voltage and electric current, low noise feature, its peripheral gain setting resistor adopts high-precision resistance, the symmetry of circuit can be improved, strengthen common mode inhibition capacity; Fully-differential amplifier output signal rear class connects low-pass filter circuit, and common mode and difference mode signal are filtered, and provides anti-aliasing effect to rear class ADC.
Analog-digital conversion circuit as described 50 is connected with two outfans of described wave filter 41, and analog-digital conversion circuit as described 50 is for being converted into digital signal by analogue signal.
Described Wilson's center reference circuit 60 includes the first to the 3rd pull down resistor RL1��RL3; One end of described first pull down resistor RL1 is connected with the outfan of the first amplifier P1 in described left arm acquisition channel 101, one end of described second pull down resistor RL2 is connected with the outfan of the first amplifier P1 in described right arm acquisition channel 102, described 3rd the next one end of resistance RL3 is connected with the outfan of the first amplifier P1 in described left lower limb acquisition channel 103, and the other end of described first, second, third pull down resistor RL1��RL3 is connected. The link node of described first, second, third pull down resistor RL1��RL3 forms a Wilson's central potential WCT, and described link node is connected with the reference signal input of described analog switch 20.
Described driven-right-leg circuit 70 is connected with the link node of described Wilson's central potential WCT, this Wilson's central potential WCT leads to suppress common mode disturbances to right lower limb through the reverse amplification circuit output of driven-right-leg circuit 70, the positive input termination reference potential of reverse amplification circuit, this current potential determines the reference potential of human body.
In the process that electrocardiosignal is acquired, left arm electrocardiosignal after described electrocardioelectrode signal sampling channel 10 gathers and processes, right arm electrocardiosignal, left lower limb electrocardiosignal and the first to the 6th shirtfront electrocardiosignal are sent to described analog switch 20. Described analog switch 20 obtains eight tunnel electrocardiosignaies by after described right arm electrocardiosignal and described left arm electrocardiosignal, described left lower limb electrocardiosignal and described left arm electrocardiosignal and described first to the 6th shirtfront electrocardiosignal and described Wilson's central potential difference successively respectively, i.e. the first limb lead signal, the second limb lead signal and six tunnel chest lead signals. Analog-digital conversion circuit as described 50 is connected with wholeheartedly electric signal processing unit (not shown), first, second limb lead signal in 8 railway digital electrocardiosignaies is carried out computing by described ECG's data compression unit, obtaining three bearings lead signals and three road augmented-lead signals, now this three bearings lead signals, three road augmented-lead signals and 8 railway digital electrocardiosignaies there are 12 together and lead electrocardiosignal.
Compared to prior art, provided by the invention 12 lead in electrocardiogram signal acquisition device, owing to fully differential amplifying circuit 40 adopts single-chip integration fully-differential amplifier P4 and the high-precision gain resistor in periphery, without adopting multiple amplifier in circuit, save board design space, circuit structure is simple, less costly, also ensure that noise and common mode rejection ratio all can reach higher index simultaneously, and baseline is sufficiently stable, signal input dynamic range is big, it is not easy to saturated, thus reliability is high, moreover it is possible to support that perfect PACE (pacemaker impulse) detects.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all within the spirit and principles in the present invention, any amendment of making, equivalent replacement, improvement etc., should be included within protection scope of the present invention.
Claims (8)
1. 12 leading an electrocardiogram signal acquisition device, it includes nine electrocardioelectrode signal sampling channels, an analog switch, a buffering and filter circuit, a fully differential amplifying circuit, an analog to digital conversion circuit, Wilson's center reference circuit and a driven-right-leg circuit; Nine electrocardioelectrode signal sampling channels include a left arm acquisition channel, a right arm acquisition channel, a left lower limb acquisition channel and the first to the 6th shirtfront acquisition channel; Nine electrocardioelectrode signal sampling channels are all connected with the input of described analog switch; The outfan of described analog switch, described buffering are sequentially connected with filter circuit, described fully differential amplifying circuit and analog-digital conversion circuit as described; Each electrocardioelectrode signal sampling channel all includes the input protection circuit, a preamplifier gain amplifying circuit and the low-pass filter circuit that are sequentially connected with; Described Wilson's center reference circuit gathers the input voltage of each low-pass filter circuit corresponding in described left arm acquisition channel, described right arm acquisition channel and described left lower limb acquisition channel, and exports a Wilson's central potential after three input voltages gathered are processed to described analog switch and described driven-right-leg circuit.
2. as claimed in claim 1 12 lead electrocardiogram signal acquisition device, it is characterised in that: described preamplifier gain amplifying circuit includes one first amplifier, one first resistance and one second resistance; The positive input of described first amplifier is connected with the outfan of described input protection circuit; the outfan of described first amplifier is connected with one end of described first resistance, and the negative input of described first amplifier is connected with the other end of described first resistance and is jointly connected to a reference potential through described second resistance.
3. as claimed in claim 2 12 lead electrocardiogram signal acquisition device, it is characterised in that: described low-pass filter circuit includes one the 3rd resistance and one first electric capacity; One end that described 3rd resistance is connected between outfan and the input of described analog switch of described first amplifier and described 3rd resistance is connected with the input of described analog switch is through described first capacity earth.
4. as claimed in claim 2 12 lead electrocardiogram signal acquisition device, it is characterised in that: described Wilson's center reference circuit includes the first to the 3rd pull down resistor; One end of described first pull down resistor is connected with the outfan of the first amplifier in described left arm acquisition channel, one end of described second pull down resistor is connected with the outfan of the first amplifier in described right arm acquisition channel, described 3rd the next one end of resistance is connected with the outfan of the first amplifier in described left lower limb acquisition channel, and the other end of described first, second, third pull down resistor is connected.
5. as claimed in claim 4 12 lead electrocardiogram signal acquisition device, it is characterized in that: the link node of described first, second, third pull down resistor forms described Wilson's central potential, and described link node is connected with described analog switch and described driven-right-leg circuit respectively.
6. as claimed in claim 1 12 lead electrocardiogram signal acquisition device, it is characterized in that: the outfan of described analog switch includes one first outfan and one second outfan, and described buffering and filter circuit include one first amplifier, one second amplifier and one second electric capacity; The positive input of described first amplifier is connected with the first outfan of described analog switch, and the negative input of described first amplifier is connected with its outfan and is commonly connected to one end of described second electric capacity and forms an outfan of described buffering and filter circuit; The positive input of described second amplifier is connected with the second outfan of described analog switch, and the negative input of described second amplifier is connected with its outfan and is commonly connected to the other end of described second electric capacity and forms another outfan of described buffering and filter circuit.
7. as claimed in claim 6 12 lead electrocardiogram signal acquisition device, it is characterised in that: described fully differential amplifying circuit includes a difference amplifier, the 4th to the 7th resistance and a wave filter; The positive input of described difference amplifier is connected with an outfan of filter circuit with described buffering by described 4th resistance, and described 5th resistance is connected between the positive input of described difference amplifier and negative sense outfan; The negative input of described difference amplifier is connected with another outfan of filter circuit with described buffering by described 6th resistance, and described 7th resistance is connected between the negative input of described difference amplifier and forward outfan; Forward outfan and the negative sense outfan of two inputs of described wave filter corresponding and described difference amplifier respectively are connected.
8. as claimed in claim 7 12 lead electrocardiogram signal acquisition device, it is characterised in that: analog-digital conversion circuit as described is connected with the outfan of described wave filter.
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| CN107296599A (en) * | 2017-05-16 | 2017-10-27 | 武汉思创电子有限公司 | A kind of multi leads ECG signal condition and data acquisition circuit |
| CN107361761A (en) * | 2017-07-11 | 2017-11-21 | 东北大学 | Portable electrocardiograph based on low-power consumption bluetooth |
| CN108065931A (en) * | 2016-11-14 | 2018-05-25 | 韦伯斯特生物官能(以色列)有限公司 | Application-specific integrated circuit (ASIC) with switching noise reduction |
| CN109567791A (en) * | 2019-01-30 | 2019-04-05 | 南京邮电大学 | A kind of low-power consumption electrocardiogram signal acquisition circuit |
| CN110269606A (en) * | 2019-08-05 | 2019-09-24 | 东北大学 | A kind of 32 road electrocardio of combined type/electromyographic signal collection system |
| WO2020150924A1 (en) * | 2019-01-23 | 2020-07-30 | 深圳迈瑞生物医疗电子股份有限公司 | Mobile monitoring system with distributed information prompting function and method thereof |
| CN112535455A (en) * | 2019-09-20 | 2021-03-23 | 深圳市理邦精密仪器股份有限公司 | Filtering method, terminal device and computer storage medium |
| CN113057638A (en) * | 2021-03-23 | 2021-07-02 | 北京蓬阳丰业科技有限公司 | Limb conduction and central potential signal acquisition circuit, electrocardiosignal acquisition system and method |
| CN115208361A (en) * | 2022-06-13 | 2022-10-18 | 曦成半导体技术(上海)有限公司 | Bioelectricity analog generator |
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| CN108065931A (en) * | 2016-11-14 | 2018-05-25 | 韦伯斯特生物官能(以色列)有限公司 | Application-specific integrated circuit (ASIC) with switching noise reduction |
| CN107296599A (en) * | 2017-05-16 | 2017-10-27 | 武汉思创电子有限公司 | A kind of multi leads ECG signal condition and data acquisition circuit |
| CN107296599B (en) * | 2017-05-16 | 2024-01-26 | 武汉思创电子有限公司 | Multi-lead ECG signal conditioning and data acquisition circuit |
| CN107361761A (en) * | 2017-07-11 | 2017-11-21 | 东北大学 | Portable electrocardiograph based on low-power consumption bluetooth |
| WO2020150924A1 (en) * | 2019-01-23 | 2020-07-30 | 深圳迈瑞生物医疗电子股份有限公司 | Mobile monitoring system with distributed information prompting function and method thereof |
| CN109567791A (en) * | 2019-01-30 | 2019-04-05 | 南京邮电大学 | A kind of low-power consumption electrocardiogram signal acquisition circuit |
| CN110269606A (en) * | 2019-08-05 | 2019-09-24 | 东北大学 | A kind of 32 road electrocardio of combined type/electromyographic signal collection system |
| CN112535455A (en) * | 2019-09-20 | 2021-03-23 | 深圳市理邦精密仪器股份有限公司 | Filtering method, terminal device and computer storage medium |
| CN113057638A (en) * | 2021-03-23 | 2021-07-02 | 北京蓬阳丰业科技有限公司 | Limb conduction and central potential signal acquisition circuit, electrocardiosignal acquisition system and method |
| CN113057638B (en) * | 2021-03-23 | 2023-04-07 | 北京蓬阳丰业科技有限公司 | Limb conduction and central potential signal acquisition circuit, electrocardiosignal acquisition system and method |
| CN115208361A (en) * | 2022-06-13 | 2022-10-18 | 曦成半导体技术(上海)有限公司 | Bioelectricity analog generator |
| CN115208361B (en) * | 2022-06-13 | 2023-04-11 | 曦成半导体技术(上海)有限公司 | Bioelectricity analog generator |
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