CN105607530B - A kind of automatization blood glucose meter - Google Patents
A kind of automatization blood glucose meter Download PDFInfo
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- CN105607530B CN105607530B CN201510745025.9A CN201510745025A CN105607530B CN 105607530 B CN105607530 B CN 105607530B CN 201510745025 A CN201510745025 A CN 201510745025A CN 105607530 B CN105607530 B CN 105607530B
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- insulin
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- blood glucose
- pulse
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- 239000008280 blood Substances 0.000 title claims abstract description 159
- 210000004369 blood Anatomy 0.000 title claims abstract description 159
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims abstract description 97
- 239000008103 glucose Substances 0.000 title claims abstract description 97
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims abstract description 210
- 102000004877 Insulin Human genes 0.000 claims abstract description 105
- 108090001061 Insulin Proteins 0.000 claims abstract description 105
- 229940125396 insulin Drugs 0.000 claims abstract description 105
- 238000001514 detection method Methods 0.000 claims abstract description 30
- 238000012360 testing method Methods 0.000 claims abstract description 25
- 238000002347 injection Methods 0.000 claims abstract description 6
- 239000007924 injection Substances 0.000 claims abstract description 6
- 238000004891 communication Methods 0.000 claims description 52
- 239000000523 sample Substances 0.000 claims description 15
- 239000007788 liquid Substances 0.000 claims description 14
- 230000005540 biological transmission Effects 0.000 claims description 8
- 238000001802 infusion Methods 0.000 claims description 8
- 230000005856 abnormality Effects 0.000 claims description 6
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- 238000010168 coupling process Methods 0.000 claims description 5
- 238000005859 coupling reaction Methods 0.000 claims description 5
- 238000010295 mobile communication Methods 0.000 claims description 5
- 208000013016 Hypoglycemia Diseases 0.000 claims description 4
- 230000015572 biosynthetic process Effects 0.000 claims description 4
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- 230000002218 hypoglycaemic effect Effects 0.000 claims description 4
- 238000003786 synthesis reaction Methods 0.000 claims description 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 3
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 238000004804 winding Methods 0.000 claims description 3
- 210000004153 islets of langerhan Anatomy 0.000 claims description 2
- 210000000496 pancreas Anatomy 0.000 claims 2
- QJVKUMXDEUEQLH-UHFFFAOYSA-N [B].[Fe].[Nd] Chemical compound [B].[Fe].[Nd] QJVKUMXDEUEQLH-UHFFFAOYSA-N 0.000 claims 1
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- TVEXGJYMHHTVKP-UHFFFAOYSA-N 6-oxabicyclo[3.2.1]oct-3-en-7-one Chemical compound C1C2C(=O)OC1C=CC2 TVEXGJYMHHTVKP-UHFFFAOYSA-N 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
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Classifications
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/04—Programme control other than numerical control, i.e. in sequence controllers or logic controllers
- G05B19/042—Programme control other than numerical control, i.e. in sequence controllers or logic controllers using digital processors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
Abstract
The present invention relates to a kind of automatization blood glucose meter, described automatization blood glucose meter includes that insulin drives equipment, insulin pump, pulse detection equipment, blood sugar test equipment and Freescale IMX6 processor, described pulse detection equipment and described blood sugar test equipment are respectively used to extract pulse data and the blood glucose level data of tested personnel, described Freescale IMX6 processor drives equipment with described insulin, described pulse detection equipment and described blood sugar test equipment connect respectively, pulse data based on described pulse detection equipment determines whether to send cacosphyxia identification signal, blood glucose level data based on described blood sugar test equipment determines whether that controlling described insulin drives equipment to drive described insulin pump for tested personnel's insulin injection.
Description
Technical field
The present invention relates to medical device fields, particularly relate to a kind of automatization blood glucose meter.
Background technology
Blood glucose, refers to glucose contained in blood.Postdigestive glucose is entered blood by small intestinal, and is transported to
Each cell in body, is the main energy sources of cell.The blood sugar concentration of normal person is the most stable, falls and can determine that at one
Blood glucose range within.
Blood glucose must keep certain level could maintain each organ internal and the needs of tissue.Blood sugar concentration typically exists
Raise after taking food one to two hours, and be preferably minimized at breakfast.Blood sugar concentration imbalance can cause multiple disease, persistence blood glucose
The hyperglycemia of excessive concentration and too low hypoglycemia cause serious impact all can to people's health, and caused by many reasons
Persistent hyperglycemia will cause diabetes, and this is also the most significant disease that blood sugar concentration is relevant.
Prior art exists the Medical Instruments of some detection blood glucose, but these blood glucose meter all exist following defect: (1) is examined
Survey pattern is single, can only detect blood sugar concentration；(2) testing mechanism falls behind, and structural redundancy is too high, and precision can not meet and increasingly increases
The accuracy requirement added；(3) there is no blood sugar test and the control mechanism of insulin supply, it is impossible to according to the blood sugar content of tested human body
The supply parameter of the insulin of self-adaptative adjustment tested personnel, such as, feed speed, quantity delivered etc., in addition it is also necessary to manual observation blood
Sugar content, manual decision's insulin supply parameter, automatization level falls behind；(4) wireless communication interface is deficient, it is impossible to will be with blood glucose
Relevant parameters is timely fed back to medical server end, even if there are some simple wireless communication interfaces, such as bluetooth
Communication interface, its matching mechanisms and connection mechanism inefficiency, can not meet the requirement of the high speed transmission data of medical device.
To this end, the present invention proposes a kind of automatization blood glucose meter, it is possible to improve the structure of the blood glucose meter fallen behind, pulse is examined
Survey is dissolved in blood glucose meter, widens the scope of the physiological parameter of detection, improves the precision of blood sugar test, it is possible to set up blood glucose automatic
The insulin delivery system controlled, reduces artificial participation, in addition it is possible to improve existing Bluetooth communication mechanism, improves wireless
The speed of data transmission and efficiency, thus, improve the intelligent level of blood glucose meter on the whole.
Summary of the invention
In order to solve the technical problem that prior art exists, the invention provides a kind of automatization blood glucose meter, pulse is examined
Measurement equipment and blood sugar test equipment work in concentrating on a detecting instrument simultaneously, optimize the knot of existing blood sugar test equipment
Structure, improve blood sugar test precision, meanwhile, add insulin pump and insulin supply control mechanism, it is achieved blood sugar concentration from
Dynamic control, particular, it is important that by matching mechanisms and the connection mechanism of improving existing bluetooth communication interface, improve blood glucose instrument
The communication efficiency of wireless connections.
According to an aspect of the present invention, it is provided that a kind of automatization blood glucose meter, described automatization blood glucose meter includes insulin
Driving equipment, insulin pump, pulse detection equipment, blood sugar test equipment and Freescale IMX6 processor, described pulse detection
Equipment and described blood sugar test equipment are respectively used to extract pulse data and blood glucose level data, the described Freescale of tested personnel
IMX6 processor drives equipment, described pulse detection equipment and described blood sugar test equipment to be connected respectively with described insulin, base
Pulse data in described pulse detection equipment determines whether to send cacosphyxia identification signal, based on described blood sugar test equipment
Blood glucose level data determine whether to control described insulin and drive equipment to drive described insulin pump to inject islets of langerhans for tested personnel
Element.
More specifically, in described automatization blood glucose meter, including the first resistance, one end is connected with 5V power supply, the other end with
The anode of infrared receiving diode connects；Second resistance, one end is connected with 5V power supply, and one end of the other end and the 3rd resistance is even
Connect；3rd resistance, other end ground connection, and there is the resistance identical with the second resistance；First two-way operational amplifier, is used for producing
The reference voltage of 2.5V, the other end of its anode and the second resistance connects, and one end of negative terminal and the first electric capacity connects, outfan and
The negative terminal of infrared-emitting diode connects, and negative terminal is also connected with the negative terminal of infrared-emitting diode；First electric capacity, another termination
Ground；4th resistance, one end is connected with the negative terminal of infrared-emitting diode；Second two-way operational amplifier, anode and the 4th resistance
The other end connect, negative terminal is connected with the anode of infrared receiving diode, and outfan is as pulse voltage；5th resistance, in parallel
Between the second two-way operational amplifier negative terminal and the second two-way operational amplifier output terminal；Second electric capacity, is connected in parallel on second pair
Between road operational amplifier negative terminal and the second two-way operational amplifier output terminal；Infrared-emitting diode, is arranged on tested personnel
Ear's blood capillary position, is used for launching infrared light, and the negative terminal of infrared-emitting diode connects with the anode of infrared receiving diode
Connect；Infrared receiving diode, is arranged on tested personnel ear blood capillary position, is positioned at the relative of described infrared-emitting diode
Position, the infrared light after receiving transmission tested personnel ear blood capillary；Direct Digital Frequency Synthesizers, is used for producing frequency
The sine wave signal that rate and phase place can adjust to be used as mixing use as rf frequency source；Pulse-series generator, is used for
Produce pulse train；Frequency mixer, is connected respectively with described Direct Digital Frequency Synthesizers and described pulse-series generator, uses
Pulse train carries out mixed modulated to sine wave signal；Power amplifier, is connected with described frequency mixer, for by after mixed modulated
Signal be amplified；Switching Power Supply, is used as the interface circuit between probe and power amplifier, the signal loading after amplifying
In the radio-frequency receiving-transmitting coil of probe；Nd-Fe-B permanent magnetic type magnet structure, produces one in the space accommodating tested personnel's finger
The uniform static magnetic field of individual field intensity；Probe, is placed on tested personnel's finger position, is wound around radio-frequency receiving-transmitting coil with the letter that will load
Number send in described Nd-Fe-B permanent magnetic type magnet structure, produce nmr phenomena, be additionally operable in tested personnel's finger
The deamplification obtained after Hydrogen Proton resonance is sent；Freescale IMX6 processor, is connected with described probe, receives described decay
Signal, analyzes the spectral line of described deamplification, and calculates wherein glucose proportion, thus the blood glucose obtaining tested personnel is dense
Degree, described Freescale IMX6 processor also outfan with described second two-way operational amplifier is connected to obtain described pulse
Voltage, and when described pulse voltage is outside default pulse range, send cacosphyxia identification signal, when described blood sugar concentration
When default blood glucose upper concentration, send blood sugar concentration too high identification signal, when described blood sugar concentration is dense at default blood glucose lower limit
When spending, send blood sugar concentration too low identification signal；Insulin storage device, for prestoring the insulin of preset capacity；Liquid
Level detection apparatus, is positioned at described insulin storage device, the insulin liquid level in detection insulin storage device in real time,
And when insulin liquid level is equal to or less than preset reference liquid level, sending insufficient insulin alarm signal, described Level Detection sets
For also being connected described insufficient insulin alarm signal is sent to described Freescale with described Freescale IMX6 processor
IMX6 processor；Insulin drives equipment, is connected with described Freescale IMX6 processor, when receiving described blood sugar concentration mistake
High when identifying signal, the blood sugar concentration that forwards according to described Freescale IMX6 processor and described default blood glucose upper concentration
Difference determines insulin pump drive signal, and described insulin pump drives the value of the supply insulin of signal deciding insulin pump
And speed；Insulin pump, connects respectively with described insulin storage device and insulin infusion device, drives with described insulin
Equipment connects, and under the control driving equipment at described insulin, is passed through by the insulin in described insulin storage device
Insulin infusion device is expelled in tested personnel's body；Insulin infusion device, detachable is embedded in tested personnel's body, uses
In to tested personnel's insulin injection；Serial communication circuit, is positioned at Freescale IMX6 processor and Bluetooth matching communication equipment
Between, for described blood sugar concentration and described insufficient insulin alarm signal are sent to Bluetooth matching communication equipment；Bluetooth
Join communication equipment, blue for the target being wirelessly transmitted to described blood sugar concentration and described insufficient insulin alarm signal connect
Tooth equipment；Described Bluetooth matching communication equipment includes the first search subset, the second search subset and coupling connexon equipment；
Wherein, the first search subset, determine, according to MAC Address concentration in Bluetooth Scatternet, the bluetooth that Bluetooth MAC address concentration is the highest
Piconet is as target piconet, and a Bluetooth Scatternet is made up of multiple micro bluetooth networks；Second search subset, with described
First search subset connects, and in described target piconet, finds, quantity preceding by signal intensity ranking and is not more than 7
One or more Bluetooth matching communication equipments are as one or more target Bluetooth devices；Equipment connexon equipment, with described
Two search subsets connect, and start and are connected with the Bluetooth communication of the one or more target Bluetooth devices；Wherein, hot outgoing
When penetrating pulseless between diode and infrared receiving diode, pulse voltage is 2.5V, when infrared-emitting diode with infrared connect
When there is, between receipts diode, the pulse beated, blood vessels make ear's light transmission be deteriorated, and pulse voltage is more than 2.5V；Wherein, first
Two-way operational amplifier and the second two-way operational amplifier are all the two-way operational amplifier of TI company；Wherein, described probe twines
Around radio-frequency receiving-transmitting coil be in birdcage coil, toroidal winding, saddle-shaped coils, phased array coils and annulus
Kind；Wherein, direct digital synthesizers, analog phase-locked look and digital phase-locking are selected in the frequency synthesis that Direct Digital Frequency Synthesizers is used
The one of Xiang Huanzhong；Wherein, when described target piconet having the quantity of Bluetooth matching communication equipment of signal for more than or equal to 7
Time, the quantity of the one or more target Bluetooth devices is 7, when the Bluetooth matching having signal in described target piconet leads to
When the quantity of letter equipment is less than 7, the quantity of the one or more target Bluetooth devices is to have letter in described target piconet
Number the quantity of Bluetooth matching communication equipment.
More specifically, in described automatization blood glucose meter: described serial communication circuit is RS232 serial communication interface.
More specifically, in described automatization blood glucose meter: described Freescale IMX6 processor is sending cacosphyxia knowledge
When level signal, blood glucose too high identification signal or hypoglycemia identification signal, be simultaneously emitted by abnormality signal, otherwise, described in fly
Think karr IMX6 processor and be simultaneously emitted by normal state signal.
More specifically, in described automatization blood glucose meter, described automatization blood glucose meter also includes: radio communication circuit, with
Described Freescale IMX6 processor connects, and is used for sending abnormality signal or normal state signal.
More specifically, in described automatization blood glucose meter: described radio communication circuit is 3G mobile communication interface or 4G shifting
Dynamic communication interface.
More specifically, in described automatization blood glucose meter, described automatization blood glucose meter also includes: FLASH storage chip, with
Described Freescale IMX6 processor connects, and is used for prestoring default pulse range, presetting blood glucose upper concentration and default blood
Sugar least concentration.
Accompanying drawing explanation
Below with reference to accompanying drawing, embodiment of the present invention are described, wherein:
Fig. 1 is the block diagram of the first embodiment of automatization's blood glucose meter of the present invention.
Reference: 1 insulin drives equipment；2 insulin pumps；3 pulse detection equipment；4 blood sugar test equipment；5 fly to think
Karr IMX6 processor
Detailed description of the invention
Below with reference to accompanying drawings the embodiment of automatization's blood glucose meter of the present invention is described in detail.
Sugar in blood is referred to as blood glucose, is the most all glucose.Needed for internal each histiocyte activity
Energy major part is from glucose, so blood glucose preferably must be held in certain level and could maintain internal each organ and the need of tissue
Ask.
The concentration of the blood glucose in human body is generally controlled in a scope the narrowest, and blood glucose is too high or too low all can give people
Affect.In order to effectively detect the blood sugar concentration in human body, occur in that multiple blood glucose meter on the market, especially for suffering from
The patient having hypertension is favored.
But, blood glucose meter of the prior art detection parameter is single, testing mechanism falls behind, and lacks blood sugar test and insulin
Supply automatically controls mechanism, and meanwhile, the wireless communication interface coupling being furnished with and joint efficiency are low, can not meet hospital
Existing requirement with patient.
To this end, the present invention has built a kind of automatization blood glucose meter, the high-precision pulse monitoring through structure optimization is set
Standby and blood glucose monitoring device is integrated in a detecting instrument, and what employing blood sugar test and insulin supplied simultaneously automatically controls mould
Bluetooth communication interface after formula and optimization, the use for patient and hospital provides more convenient.
Fig. 1 is the block diagram of the first embodiment of automatization's blood glucose meter of the present invention, described automatization blood glucose meter bag
Include insulin and drive equipment, insulin pump, pulse detection equipment, blood sugar test equipment and Freescale IMX6 processor, described
Pulse detection equipment and described blood sugar test equipment are respectively used to extract the pulse data of tested personnel and blood glucose level data, described in fly
Thinking karr IMX6 processor drives equipment, described pulse detection equipment and described blood sugar test equipment to connect respectively with described insulin
Connecing, pulse data based on described pulse detection equipment determines whether to send cacosphyxia identification signal, examines based on described blood glucose
The blood glucose level data of measurement equipment determines whether that controlling described insulin drives equipment to drive described insulin pump to note for tested personnel
Penetrate insulin.
Then, continue the concrete structure of the second embodiment of automatization's blood glucose meter of the present invention is carried out further
Bright.
Described automatization blood glucose meter includes: the first resistance, and one end is connected with 5V power supply, the other end and infrared receiving diode
Anode connect；Second resistance, one end is connected with 5V power supply, and one end of the other end and the 3rd resistance connects；3rd resistance, another
End ground connection, and there is the resistance identical with the second resistance.
Described automatization blood glucose meter includes: the first two-way operational amplifier, for producing the reference voltage of 2.5V, its anode
Being connected with the other end of the second resistance, one end of negative terminal and the first electric capacity connects, outfan and the negative terminal of infrared-emitting diode
Connecting, negative terminal is also connected with the negative terminal of infrared-emitting diode；First electric capacity, other end ground connection；4th resistance, one end is with infrared
The negative terminal of emitting diode connects；Second two-way operational amplifier, the other end of anode and the 4th resistance connects, and negative terminal is with infrared
The anode of reception diode connects, and outfan is as pulse voltage.
Described automatization blood glucose meter includes: the 5th resistance, is connected in parallel on the second two-way operational amplifier negative terminal and the second two-way
Between operational amplifier output terminal；Second electric capacity, is connected in parallel on the second two-way operational amplifier negative terminal and the second two-way operation amplifier
Between device outfan；Infrared-emitting diode, is arranged on tested personnel ear blood capillary position, is used for launching infrared light, red
The negative terminal of emission diode is connected with the anode of infrared receiving diode；Infrared receiving diode, is arranged on tested personnel's ear
Blood capillary position, portion, is positioned at the relative position of described infrared-emitting diode, is used for receiving transmission tested personnel ear capillary
Infrared light after blood vessel.
Described automatization blood glucose meter includes: Direct Digital Frequency Synthesizers, for producing frequency and phase place can adjust
Sine wave signal to be used as mixing use as rf frequency source；Pulse-series generator, is used for producing pulse train；Mixing
Device, is connected respectively with described Direct Digital Frequency Synthesizers and described pulse-series generator, uses pulse train to sine wave
Signal carries out mixed modulated；Power amplifier, is connected with described frequency mixer, for being amplified by the signal after mixed modulated.
Described automatization blood glucose meter includes: Switching Power Supply, is used as the interface circuit between probe and power amplifier, will put
Signal loading after great to probe radio-frequency receiving-transmitting coil in；Nd-Fe-B permanent magnetic type magnet structure, is accommodating tested personnel's finger
Space in produce a uniform static magnetic field of field intensity；Probe, is placed on tested personnel's finger position, is wound around radio-frequency receiving-transmitting line
Enclose the signal loading and send in described Nd-Fe-B permanent magnetic type magnet structure, produce nmr phenomena, be additionally operable to pass through
The deamplification obtained after Hydrogen Proton resonance in tested personnel's finger is sent.
Described automatization blood glucose meter includes: Freescale IMX6 processor, is connected with described probe, receives described decay letter
Number, analyze the spectral line of described deamplification, and calculate wherein glucose proportion, thus the blood glucose obtaining tested personnel is dense
Degree, described Freescale IMX6 processor also outfan with described second two-way operational amplifier is connected to obtain described pulse
Voltage, and when described pulse voltage is outside default pulse range, send cacosphyxia identification signal, when described blood sugar concentration
When default blood glucose upper concentration, send blood sugar concentration too high identification signal, when described blood sugar concentration is dense at default blood glucose lower limit
When spending, send blood sugar concentration too low identification signal.
Described automatization blood glucose meter includes: insulin storage device, for prestoring the insulin of preset capacity；Liquid level
Detection equipment, is positioned at described insulin storage device, the insulin liquid level in detection insulin storage device in real time, and
When insulin liquid level is equal to or less than preset reference liquid level, send insufficient insulin alarm signal, described liquid level detection device
Also it is connected described insufficient insulin alarm signal is sent to described Freescale with described Freescale IMX6 processor
IMX6 processor.
Described automatization blood glucose meter includes: insulin drives equipment, is connected, when connecing with described Freescale IMX6 processor
When receiving described blood sugar concentration too high identification signal, the blood sugar concentration and described forwarded according to described Freescale IMX6 processor
The difference presetting blood glucose upper concentration determines insulin pump drive signal, and described insulin pump drives signal deciding insulin pump
The supply value of insulin and speed；Insulin pump, with described insulin storage device and insulin infusion device phase respectively
Connect, drive equipment to be connected with described insulin, under the control driving equipment at described insulin, described insulin is stored
Insulin in equipment is expelled in tested personnel's body by insulin infusion device.
Described automatization blood glucose meter includes: insulin infusion device, detachable is embedded in tested personnel's body, for
Tested personnel's insulin injection；Serial communication circuit, between Freescale IMX6 processor and Bluetooth matching communication equipment,
For described blood sugar concentration and described insufficient insulin alarm signal are sent to Bluetooth matching communication equipment.
Described automatization blood glucose meter includes: Bluetooth matching communication equipment, for by described blood sugar concentration and described insulin
Not enough alarm signal is wirelessly transmitted to the target Bluetooth devices connected；Described Bluetooth matching communication equipment includes the first search
Equipment, the second search subset and coupling connexon equipment.
Wherein, the first search subset, determine that Bluetooth MAC address concentration is according to MAC Address concentration in Bluetooth Scatternet
High micro bluetooth network is as target piconet, and a Bluetooth Scatternet is made up of multiple micro bluetooth networks；Second search sets
Standby, is connected with described first search subset, in described target piconet, searching presses that signal intensity ranking is preceding, quantity
One or more Bluetooth matching communication equipments of no more than 7 are as one or more target Bluetooth devices；Equipment connexon equipment,
It is connected with described second search subset, starts and be connected with the Bluetooth communication of the one or more target Bluetooth devices.
Wherein, between infrared-emitting diode and infrared receiving diode during pulseless, pulse voltage is 2.5V, hot
When there is, between emission diode and infrared receiving diode, the pulse beated, blood vessels make ear's light transmission be deteriorated, pulse electricity
Pressure is more than 2.5V；Wherein, the first two-way operational amplifier and the second two-way operational amplifier are all that the two-way computing of TI company is put
Big device.
Wherein, the radio-frequency receiving-transmitting coil that described probe is wound around is birdcage coil, toroidal winding, saddle-shaped coils, phased array
One in alignment circle and annulus；Wherein, Direct Digital is selected in the frequency synthesis that Direct Digital Frequency Synthesizers is used
One in synthesis, analog phase-locked look and digital phase-locked loop.
Wherein, when being more than or equal to 7 when described target piconet has the quantity of Bluetooth matching communication equipment of signal, institute
The quantity stating one or more target Bluetooth devices is 7, when the Bluetooth matching communication having signal in described target piconet sets
When standby quantity is less than 7, the quantity of the one or more target Bluetooth devices is to have signal in described target piconet
The quantity of Bluetooth matching communication equipment.
Alternatively, in described automatization blood glucose meter: described serial communication circuit is RS232 serial communication interface；Described
Freescale IMX6 processor is sending cacosphyxia identification signal, blood glucose too high identification signal or hypoglycemia identification signal
Time, it is simultaneously emitted by abnormality signal, otherwise, described Freescale IMX6 processor is simultaneously emitted by normal state signal；Described
Automatization's blood glucose meter also includes: radio communication circuit, is connected with described Freescale IMX6 processor, is used for sending abnormality
Signal or normal state signal；Described radio communication circuit is 3G mobile communication interface or 4G mobile communication interface；Described automatically
Change blood glucose meter also to include: FLASH storage chip, be connected with described Freescale IMX6 processor, be used for prestoring default arteries and veins
Fight scope, preset blood glucose upper concentration and default blood glucose least concentration.
It addition, operational amplifier (being called for short " amplifier ") is the circuit unit with very high-amplification-factor.In side circuit,
Generally combine feedback network and collectively constitute certain functional module.He is a kind of with special Coupling circuit and the amplifier of feedback.
Its output signal can be that input signal adds, subtracts or the result of the mathematical operation such as differential, integration.Owing to being applied to simulation meter in early days
In calculation machine, in order to realize mathematical operation, therefore gain the name " operational amplifier ".
Amplifier is a circuit unit named from the angle of function, can be realized by discrete device, it is also possible to realize
In the middle of semiconductor chip.Along with the development of semiconductor technology, most amplifier is presented in single-chip.Amplifier
Of a great variety, it is widely used in the middle of electron trade.
Use automatization's blood glucose meter of the present invention, fall behind and radio communication function for blood glucose apparatus structure in prior art
The technical problem of difference, optimizes the structure of existing blood glucose instrument, adds pulse detection equipment and blood sugar concentration automatic controlling device,
The most also improve the communication performance of existing bluetooth communication interface, thus improve the level of its medical services.
Although it is understood that the present invention discloses as above with preferred embodiment, but above-described embodiment being not used to
Limit the present invention.For any those of ordinary skill in the art, without departing under technical solution of the present invention ambit,
Technical solution of the present invention is made many possible variations and modification by the technology contents that all may utilize the disclosure above, or is revised as
Equivalent embodiments with change.Therefore, every content without departing from technical solution of the present invention, according to the technical spirit pair of the present invention
Any simple modification made for any of the above embodiments, equivalent variations and modification, all still fall within the scope of technical solution of the present invention protection
In.
Claims (1)
1. automatization's blood glucose meter, described automatization blood glucose meter includes that insulin drives equipment, insulin pump, pulse detection to set
Standby, blood sugar test equipment and Freescale IMX6 processor, described pulse detection equipment and described blood sugar test equipment are used respectively
In pulse data and the blood glucose level data of extraction tested personnel, described Freescale IMX6 processor drives with described insulin and sets
Pulse detection equipment standby, described and described blood sugar test equipment connect respectively, pulse data based on described pulse detection equipment
Determining whether to send cacosphyxia identification signal, blood glucose level data based on described blood sugar test equipment determines whether to control described pancreas
Island element drives equipment to drive described insulin pump for tested personnel's insulin injection；
It is characterized in that, described automatization blood glucose meter also includes:
First resistance, one end is connected with 5V power supply, and the other end is connected with the anode of infrared receiving diode；
Second resistance, one end is connected with 5V power supply, and one end of the other end and the 3rd resistance connects；
3rd resistance, other end ground connection, and there is the resistance identical with the second resistance；
First two-way operational amplifier, for producing the reference voltage of 2.5V, the other end of its anode and the second resistance connects, negative
End be connected with one end of the first electric capacity, outfan is connected with the negative terminal of infrared-emitting diode, negative terminal also with infrared emission two pole
The negative terminal of pipe connects；
First electric capacity, other end ground connection；
4th resistance, one end is connected with the negative terminal of infrared-emitting diode；
Second two-way operational amplifier, the other end of anode and the 4th resistance connects, negative terminal and the anode of infrared receiving diode
Connecting, outfan is as pulse voltage；
5th resistance, is connected in parallel between the second two-way operational amplifier negative terminal and the second two-way operational amplifier output terminal；
Second electric capacity, is connected in parallel between the second two-way operational amplifier negative terminal and the second two-way operational amplifier output terminal；
Infrared-emitting diode, is arranged on tested personnel ear blood capillary position, is used for launching infrared light, infrared emission two pole
The negative terminal of pipe is connected with the anode of infrared receiving diode；
Infrared receiving diode, is arranged on tested personnel ear blood capillary position, is positioned at the phase of described infrared-emitting diode
Infrared light to position, after receiving transmission tested personnel ear blood capillary；
Direct Digital Frequency Synthesizers, for producing frequency and sine wave signal that phase place can adjust is using as rf frequency source
It is used as mixing to use；
Pulse-series generator, is used for producing pulse train；
Frequency mixer, is connected respectively with described Direct Digital Frequency Synthesizers and described pulse-series generator, uses pulse train
Sine wave signal is carried out mixed modulated；
Power amplifier, is connected with described frequency mixer, for being amplified by the signal after mixed modulated；
Switching Power Supply, is used as the interface circuit between probe and power amplifier, signal loading the penetrating to probe after amplifying
Frequently in dispatch coil；
Nd-Fe-B permanent magnetic type magnet structure, produces a uniform static-magnetic of field intensity in the space accommodating tested personnel's finger
?；
Probe, is placed on tested personnel's finger position, is wound around radio-frequency receiving-transmitting coil and sends into described neodymium iron boron with the signal that will load
In permanent-magnet type magnet structure, produce nmr phenomena, be additionally operable to through obtaining after Hydrogen Proton resonance in tested personnel's finger
Deamplification send；
Freescale IMX6 processor, is connected with described probe, receives described deamplification, analyze the spectrum of described deamplification
Line, and calculate wherein glucose proportion, thus obtain the blood sugar concentration of tested personnel, described Freescale IMX6 processor
The also outfan with described second two-way operational amplifier is connected to obtain described pulse voltage, and when described pulse voltage is in advance
If time outside pulse range, send cacosphyxia identification signal, when described blood sugar concentration is at default blood glucose upper concentration, send
Blood sugar concentration too high identification signal, when described blood sugar concentration is at default blood glucose least concentration, sends the too low identification of blood sugar concentration
Signal；
Insulin storage device, for prestoring the insulin of preset capacity；
Liquid level detection device, is positioned at described insulin storage device, the islets of langerhans in detection insulin storage device in real time
Element liquid level, and when insulin liquid level is equal to or less than preset reference liquid level, send insufficient insulin alarm signal, described liquid level
Detection equipment is also connected with described Freescale IMX6 processor and flies described in described insufficient insulin alarm signal being sent to
Think karr IMX6 processor；
Insulin drives equipment, is connected with described Freescale IMX6 processor, when receiving the too high identification of described blood sugar concentration
During signal, the blood sugar concentration forwarded according to described Freescale IMX6 processor and the difference of described default blood glucose upper concentration are true
Determining insulin pump drive signal, described insulin pump drives value and the speed of the supply insulin of signal deciding insulin pump
Degree；
Insulin pump, connects respectively with described insulin storage device and insulin infusion device, drives with described insulin and sets
Standby connection, under the control driving equipment at described insulin, passes through pancreas by the insulin in described insulin storage device
Island element injection device is expelled in tested personnel's body；
Insulin infusion device, detachable is embedded in tested personnel's body, for tested personnel's insulin injection；
Serial communication circuit, between Freescale IMX6 processor and Bluetooth matching communication equipment, for by described blood glucose
Concentration and described insufficient insulin alarm signal are sent to Bluetooth matching communication equipment；
Bluetooth matching communication equipment, for being wirelessly transmitted to connection by described blood sugar concentration and described insufficient insulin alarm signal
On target Bluetooth devices；Described Bluetooth matching communication equipment includes the first search subset, the second search subset and coupling
Connexon equipment；Wherein, the first search subset, determine Bluetooth MAC address concentration according to MAC Address concentration in Bluetooth Scatternet
The highest micro bluetooth network is as target piconet, and a Bluetooth Scatternet is made up of multiple micro bluetooth networks；Second search
Equipment, is connected with described first search subset, and in described target piconet, it is preceding, several that signal intensity ranking is pressed in searching
Amount is not more than one or more Bluetooth matching communication equipments of 7 as one or more target Bluetooth devices；Equipment connexon sets
Standby, it is connected with described second search subset, starts and be connected with the Bluetooth communication of the one or more target Bluetooth devices；
Wherein, between infrared-emitting diode and infrared receiving diode during pulseless, pulse voltage is 2.5V, hot outgoing
Penetrating when there is, between diode and infrared receiving diode, the pulse beated, blood vessels make ear's light transmission be deteriorated, and pulse voltage is big
In 2.5V；
Wherein, the first two-way operational amplifier and the second two-way operational amplifier are all the two-way operational amplifier of TI company；
Wherein, the radio-frequency receiving-transmitting coil that described probe is wound around is birdcage coil, toroidal winding, saddle-shaped coils, phased array alignment
One in circle and annulus；
Wherein, direct digital synthesizers, analog phase-locked look and numeral are selected in the frequency synthesis that Direct Digital Frequency Synthesizers is used
One in phaselocked loop；
Wherein, when being more than or equal to 7 when described target piconet has the quantity of Bluetooth matching communication equipment of signal, described one
Individual or multiple target Bluetooth devices quantity is 7, when the Bluetooth matching communication equipment having signal in described target piconet
When quantity is less than 7, the quantity of the one or more target Bluetooth devices is the bluetooth having signal in described target piconet
The quantity of matched communicating devices；
Described serial communication circuit is RS232 serial communication interface；
Described Freescale IMX6 processor is sending cacosphyxia identification signal, blood glucose too high identification signal or hypoglycemia knowledge
During level signal, being simultaneously emitted by abnormality signal, otherwise, described Freescale IMX6 processor is simultaneously emitted by normal condition letter
Number；
Radio communication circuit, is connected with described Freescale IMX6 processor, is used for sending abnormality signal or normal condition
Signal；
Described radio communication circuit is 3G mobile communication interface or 4G mobile communication interface；
FLASH storage chip, is connected with described Freescale IMX6 processor, is used for prestoring default pulse range, presetting
Blood glucose upper concentration and default blood glucose least concentration.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105455823A (en) * | 2015-11-05 | 2016-04-06 | 张宏业 | Automated blood glucose meter |
| CN108619618A (en) * | 2018-05-29 | 2018-10-09 | 北京星辰万有科技有限公司 | A kind of diabetes physical-therapy device |
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