CN105596811A - Traditional Chinese medicine composition mainly used for treating atherosclerosis, and preparation method thereof - Google Patents

Traditional Chinese medicine composition mainly used for treating atherosclerosis, and preparation method thereof Download PDF

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CN105596811A
CN105596811A CN201510758584.3A CN201510758584A CN105596811A CN 105596811 A CN105596811 A CN 105596811A CN 201510758584 A CN201510758584 A CN 201510758584A CN 105596811 A CN105596811 A CN 105596811A
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infiltrate
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root
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不公告发明人
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536—Prunella or Brunella (selfheal)
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Abstract

The invention discloses a traditional Chinese medicine composition mainly used for treating atherosclerosis. The traditional Chinese medicine composition is mainly prepared from following bulk drugs, by mass, 8 to 14 parts of spica prunellae, 10 to 15 parts of buckwheat, 7 to 12 parts of root and rhizome of ripqrian greenbrier, 5 to 11 parts of hawthorn fruit, 7 to 13 parts of stem and leaf of kwangtung beautyberry, 6 to 10 parts of flos rosae chinensis, 8 to 13 parts of all-grass of khas aletris, 5 to 12 parts of lance asiabell root, 7 to 14 parts of root or leaf of ervatamia hainanensis tsiang, 8 to 12 parts of herb of henbit deadnettle, 9 to 15 parts of corn stigma, 4 to 10 parts of auricularia auricular, 9 to 16 parts of oriental sesame seed, 7 to 15 parts of flos chrysanthemi Indici, and 9 to 13 parts of herba ecliptae. The traditional Chinese medicine composition is prepared based on summarization of clinical practice of decades, is capable of invigorate blood circulation and dredging collaterals, and nourishing liver and kidney, and is excellent in curative effect.

Description

Cure mainly atherosclerotic Chinese medicine composition and method for making
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to and cure mainly atherosclerotic Chinese medicine composition and method for making.
Background technology
Atherosclerotic is most important one common in one group of arteriosclerotic angiosis, is characterized in getting involved movingArteries and veins pathology is from inner membrance. Generally first have that lipid and compound carbohydrate gather, hemorrhage and thrombosis, proliferation of fibrous tissue and calcareousCalmness, and have medial transformation gradually and calcification, pathology is often involved elasticity and large medium muscular artery, once develop into footWith obstructing arterial chamber, the tissue that this artery is supplied or organ are by ischemic or necrosis. Due to the lipid gathering at endarteriumOutward appearance is yellow congee sample, is therefore called atherosclerotic.
Publication No. CN104189464A(application number 201410414050.4) Chinese patent literature disclose one and controlledTreat atherosclerotic Chinese medicine preparation, it is characterized in that: this formula by quality proportioning is: hawthorn 22-27 part, fleece-flower root 12-17Part, sealwort 27-33 part, honeysuckle 7-12 part, can make decoction, paste, spray, concentrated sheet, ball by the powder of this compositionDeng agent. Publication No. CN104940846A(application number 201510430839.3) Chinese patent literature disclose one and treated movingChinese medicine composition of pulse atherosclerosis and preparation method thereof, belongs to the field of Chinese medicines. This Chinese medicine composition be the tuber of pinellia, the red sage root, Radix Codonopsis,The bulk drugs such as the capsule of weeping forsythia, the membrane of a chicken's gizzard, root tuber of aromatic turmeric, Rhizoma Sparganii, curcuma zedoary, Poria cocos, cassia twig, the root of herbaceous peony, adopt respectively water according to medicine heterogeneityThe mode effective component extractings such as decoction, alcohol extract, after concentrating, be dried, pulverize, add conventional pharmaceutic adjuvant to can be made into capsuleAgent, tablet, granule, powder or pill. Publication No. CN102670893A(application number 201210175181.2) China specialProfit document discloses one and has treated atherosclerotic Chinese medicine, is prepared from: Radix Astragali 50-by the crude drug of following weight portion70, Radix Angelicae Sinensis 8-12, radix paeoniae rubrathe 8-12, earthworm 8-12, Ligusticum wallichii 8-12, safflower 5-7, peach kernel 8-12, rhizoma pinellinae praeparata 8-12, Fructus Aurantii 8-12.
Being used for the treatment of at present atherosclerotic medicine has much, and some drugs can only be alleviated illness, can not reach thoroughThe effect that the end cures, treatment by Chinese herbs safety, without bounce-back, for providing a kind of curative effect reliable, cheap Chinese medicine preparation, needs to strengthenTo research in this respect.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of effect significantly, to take safe and applicable property wideCure mainly atherosclerotic Chinese medicine composition and method for making.
Technical scheme of the present invention is:
Cure mainly atherosclerotic Chinese medicine composition, be mainly prepared from by following bulk drugs, be mass parts: selfheal 8-14; Buckwheat 10-15; Riparian greenbrier root and rhizome 7-12; Hawthorn 5-11; Kwangtung beautyberry stem and leaf 7-13; China rose 6-10; Khas aletris herb 8-13; Lance asiabell root 5-12;Hainan Ervatamia Root 7-14; Benbie 8-12; Corn stigma 9-15; Auricularia auriculajudae 4-10; Oriental sesame seed 9-16; Mother chrysanthemum 7-15; Eclipta 9-13.
Preferred version is, selfheal 10-12; Buckwheat 11-14; Riparian greenbrier root and rhizome 9-10; Hawthorn 7-9; Kwangtung beautyberry stem and leaf 9-11; China rose7-9; Khas aletris herb 9-12; Lance asiabell root 7-10; Hainan Ervatamia Root 9-12; Benbie 9-11; Corn stigma 11-13; Auricularia auriculajudae 6-8; Oriental sesame seed 11-14; Mother chrysanthemum 9-13; Eclipta 10-12.
More preferably, selfheal 11; Buckwheat 12.5; Riparian greenbrier root and rhizome 9.5; Hawthorn 8; Kwangtung beautyberry stem and leaf 10; China rose 8; Hundred tastesGinseng 10.5; Lance asiabell root 8.5; Hainan Ervatamia Root 10.5; Benbie 10; Corn stigma 12; Auricularia auriculajudae 7; Oriental sesame seed 12.5; Mother chrysanthemum 11; China ink droughtLotus 11.
The preparation method of the decoction of described Chinese medicine composition, step is as follows:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, infiltrate 12-24 minute with ginger juice (preferred: to infiltrate 16-20 minute; Be more preferably: infiltrate 18 minutes), take out slow fireDry;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), take out and be placed in steamer, to steam 20 minutes with vinegar water, taking-up is dried in the airDry;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerMaterial medicine quality 6-8 water (preferred: the water that adds 7 times of boiled bulk drug quality) doubly decocts to boiling, and turn little fire and continue to decoct,Filtering and collecting filter liquid, filter residue is stand-by;
(5) the made bulk drug of step (1) (2) (3) is mixed with the last dregs of a decoction of step (4), add water and again decoct 20 minutes, filterObtain filtrate, and mix with step (4) gained filtrate, obtain decoction.
The preparation method of described Chinese medicine composition decoction, the little fire of step (4) continues to decoct 22-34 minute (preferably: littleFire continues to decoct 26-30 minute; Be more preferably: little fire continues to decoct 28 minutes).
The preparation method of the granule of described Chinese medicine composition, step is as follows:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, infiltrate 12-24 minute with ginger juice (preferred: to infiltrate 16-20 minute; Be more preferably: infiltrate 18 minutes), take out slow fireDry;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), take out and be placed in steamer, to steam 20 minutes with vinegar water, taking-up is dried in the airDry;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerMaterial medicine quality 6-8 water (preferred: the water that adds 7 times of boiled bulk drug quality) doubly decocts to boiling, then adds step (1)(2) (3) made bulk drug, turns little fire and continues to decoct 20-28 minute (preferably: continue to decoct 22-26 minute; Be more preferably:Continue to decoct 24 minutes), filtering and collecting filter liquid;
(5) heating of step (4) gained filtrate is condensed into cream clearly, adds auxiliary material cane sugar powder to mix, make softwood, be pressed through sieveNet, granulation, dries whole grain, and sterilizing encapsulation, obtains granule.
The preparation method of described Chinese medicinal composition granules, the order number of step (5) screen cloth is that 12-24 order is (preferred: sieveThe order number of net is 16-20 order; Be more preferably: the order number of screen cloth is 18 orders).
The preparation method of the capsule of described Chinese medicine composition, step is as follows:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, infiltrate 12-24 minute with ginger juice (preferred: to infiltrate 16-20 minute; Be more preferably: infiltrate 18 minutes), take out slow fireDry;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), take out and be placed in steamer, to steam 20 minutes with vinegar water, taking-up is dried in the airDry;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerMaterial medicine quality 6-8 water (preferred: the water that adds 7 times of boiled bulk drug quality) doubly decocts to boiling, then adds step (1)(2) (3) made bulk drug, turns little fire and continues to decoct 20-28 minute (preferably: continue to decoct 22-26 minute; Be more preferably:Continue to decoct 24 minutes), filtering and collecting filter liquid;
(5) spraying drying steps (4) gained filtrate, will be dried thing and pulverize and sieve, and make medicinal powder, be packed in capsule, obtain glueWafer.
The preparation method of described Chinese medicinal composition capsules agent, it is (preferred: to pulverize that step (5) was pulverized 90-160 mesh sieveCross 110-140 mesh sieve; Be more preferably: pulverized 125 mesh sieves).
The preparation method of described Chinese medicine composition soft extract, step is as follows:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, infiltrate 12-24 minute with ginger juice (preferred: to infiltrate 16-20 minute; Be more preferably: infiltrate 18 minutes), take out slow fireDry;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), take out and be placed in steamer, to steam 20 minutes with vinegar water, taking-up is dried in the airDry;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerMaterial medicine quality 6-8 water (preferred: the water that adds 7 times of boiled bulk drug quality) doubly decocts to boiling, turns little fire and continues to decoct20-28 minute (preferred: to continue to decoct 22-26 minute; Be more preferably: continue to decoct 24 minutes), filtering and collecting filter liquid,Filter residue is stand-by;
(5) the made bulk drug of step (1) (2) (3) is mixed with the last dregs of a decoction of step (4), add water and again decoct 15 minutes, filterObtain filtrate, and mix with step (4) gained filtrate, heating is concentrated into cream clearly, obtains soft extract.
The preparation method of described Chinese medicine composition soft extract, it is 1.08-1.16 that step (5) heating is concentrated into relative densityClear cream (75 DEG C) (preferred: heating is concentrated into the clear cream that relative density is 1.10-1.14; Be more preferably: heating is concentrated intoRelative density is 1.12 clear cream).
Provided by the inventionly cure mainly atherosclerotic Chinese medicine composition scientific formulation, preparation method is simple. Remove this itOutward, its good part also shows:
1, products obtained therefrom of the present invention, result for the treatment of is good, safe and non-stimulating, can treat both principal and secondary aspect of disease;
2, this formula is summed up and is formed through clinical practice for many years, has effect promoting blood circulation and removing obstruction in channels, liver-kidney tonifying;
3, the selected Chinese medicine of the present invention, wide material sources, cheap, do not increase patient economy burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
The pharmacology of the present invention's main Chinese medicine material used is as follows:
Selfheal: base is former: be the fruit ear of labiate selfheal. Nature and flavor with return through: pungent, bitter, cold. Return liver, gallbladder channel. There is clearing liverPurging intense heat, improving eyesight, effect of mass dissipating and swelling eliminating. For red eye, swell pain, order pearl nyctalgia, has a headache dizzy, scrofula, and goiter and tumor, acute mastitis, newborn addiction,Swollen breasts.
Buckwheat: base is former: be the seed of polygonaceae plant buckwheat. Nature and flavor: sweet; Micro-acid; Cold in nature. Gui Jing: spleen; Stomach; Large intestine channel. MeritCan cure mainly: invigorating the spleen disappears long-pending; The wide intestines of lower gas; Removing toxic substances sore. Main stomach is stagnant; Have loose bowels; Dysentery; Strand intestinal cancer; White sand; Under band; Spontaneous perspiration;Night sweat; Bleb; Erysipelas; Ulcer; Carbuncle on the back; Scrofula disease; Burn and scald.
Riparian greenbrier root and rhizome: base is former: be the root and rhizome of liliaceous plant riparian greenbrier root and rhizome. Nature and flavor: sweet; Bitter; Flat. Gui Jing: liver; Lung channel.Function cures mainly: wines used as antirheumatic; Network stimulates the menstrual flow; Expelling phlegm and arresting coughing. Main air arthritis with fixed pain caused by dampness card; Internal lesion caused by overexertion pain in the back; Traumatic injury; Cough and asthma.
Hawthorn: base is former: be the fruit of rosaceous plant hawthorn or fructus crataegi cuneatae. Chemical analysis: containing epicatechin, Quercetin,Hyperin, chlorogenic acid, crataegolic acid, citric acid, amygdalin etc. Nature and flavor: acid is sweet, tepor. Gui Jing: enter spleen, stomach, Liver Channel. MeritCan cure mainly: help digestion long-pending, loose hemostasis, expelling tenia. Control meat long-pending, abdominal mass, phlegm and retained fluid, ruffian is full, and acid regurgitation rushes down dysentery, intestines wind, pain in the back, hernia is producedRear postpartum abdominal pain, lochiorrhagia, children's's breast food is stagnated. Food digesting stomach fortifying, the promoting the circulation of qi stasis of blood of faling apart. For carnivorous stagnant, stomach alkane turgor, rush down dysentery abdomenBitterly, hemostasis through closing, postpartum stasis blocking, trusted subordinate's shouting pain, hernia pain, hyperlipemia.
Kwangtung beautyberry stem and leaf: base is former: be the cauline leaf of dicotyledon medicine Verbenaceae callicarpa kwangtungensis Chun. Nature and flavor: sour and astringent; Temperature. ReturnWarp: liver; Spleen; Stomach warp. Function cures mainly: pain relieving; Hemostasis. Main haematemesis; Antimigraine; Treating swelling and pain by traumatic injury; Traumatism and bleeding.
China rose: base is former: be the flower of rosaceous plant China rose. Nature and flavor: sweet; Temperature; Nontoxic. Gui Jing: liver; Kidney channel. FunctionCure mainly: promoting blood circulation for regulating menstruation; Removing toxicity for detumescence. Main irregular menstruation; Dysmenorrhoea; Amenorrhoea; Traumatic injury; Blood stasis and swelling pain; Scrofula; Carbuncle is swollen; Scald.
Khas aletris herb: base is former: be the herb of liliaceous plant Honoka alertris spicata. Nature and flavor: hide pungent; Micro-hardship; Warm in nature. Gui Jing:Lung; Liver Channel. Function cures mainly: qi-restoratives arrest sweating; Hemostasis. The empty hidrosis of main body; Night sweat; Neurasthenia; Spit blood; Have blood in stool.
Lance asiabell root: base is former: be the root of Campanulaceae sheep breast. Nature and flavor: taste is sweet; Pungent; Property is put down. Gui Jing: return spleen; Lung channel. MeritCan cure mainly: supplementing qi and nourishing yin; Removing toxicity for detumescence; Apocenosis; Logical breast. Main spiritlessness and weakness; Dizziness headache; Lung carbuncle; Acute mastitis; Intestines future; Sore furunclePyogenic infections; Tonsillitis; Scrofula; Postpartum, breast was few; Leukorrhea; Venomous snake bite.
Hainan Ervatamia Root: base is former: be root or the leaf of apocynaceae plant Ervatamia hainanensis. Nature and flavor: hardship; Pungent; Cool in nature. Gui Jing: liver;Stomach; Large intestine channel. Function cures mainly: clearing heat and detoxicating; Step-down; Swelling and pain relieving. Main high blood pressure; Abscess of throat; Arthralgia due to wind-dampness; Fall to beat and damageWound; The carbuncle sore furuncle that swells; Venomous snake bite.
Benbie: base is former: be the herb of labiate benbie. Nature and flavor: taste is pungent; Bitter; Slightly warm in nature. Function cures mainly: liveBlood dredging collateral; Removing toxicity for detumescence. Main traumatic injury; Arthralgia and myalgia; Numb limb; Hemiplegia; Face is completed; Jaundice; Nasosinusitis; Scrofula; SwollenPoison; Impetigo.
Corn stigma: base is former: be the zeistic style of grass and column cap. Nature and flavor: taste is sweet; Light; Property is put down. Gui Jing: kidney;Stomach; Liver; Gallbladder channel. Function cures mainly: inducing diuresis to reduce edema; Clearing liver cholagogic. Main oedema; Dribbling urination; Jaundice; Cholecystitis; Gall stone; High bloodPress; Diabetes; Alactation.
Auricularia auriculajudae: base is former: be the fructification of Auriculariaceae fungi auricularia auriculajudae, Uricularia polytricha and wrinkle auricularia auriculajudae. Nature and flavor: sweet; Flat. Gui Jing: enterStomach, large intestine channel. Function cures mainly: benefiting qi and nourishing blood; Moisten the lung and relieve the cough; Hemostasis; Step-down; Anticancer. Main Qi and blood deficiency; Chronic cough of deficiency lung; Hemoptysis;Bleeding from five sense organs or subcutaneous tissue; Bloody flux; Hemorrhoid hemorrhage; Woman uterine bleeding; Hypertension; Fundus hemorrhage; Cervix cancer; Carcinoma of vagina; Injuries from falls as well.
Oriental sesame seed: base is former: be the black seed of Pedaliaceae plant sesame. Nature and flavor: sweet, flat. Gui Jing: enter liver, kidney channel. FunctionCure mainly: filling liver kidney, moisturizing viscera. Control kidney deficiency and liver, empty wind is dizzy, wandering arthritis, paralysis, and dry feces, empty thin after being ill, poliosis,Married woman's breast is few.
Mother chrysanthemum: base is former: be the flower of feverfew mother chrysanthemum and lavandulaleaf dendranthema herb. Nature and flavor: bitter; Pungent; Property is put down. Gui Jing: return lung; LiverWarp. Function cures mainly: clearing heat and detoxicating; The flat liver of dispelling wind. Main furunculosis; Ulcer; Erysipelas; Eczema; Dermatitis; Anemopyretic cold; Abscess of throat; HighBlood pressure diseases.
Eclipta: base is former: be the dry aerial parts of feverfew Eclipta prostrata. Nature and flavor with return through: sweet, sour, cold. Return kidney, liverWarp. Function with cure mainly: nourishing liver and kidney, cooling blood and hemostasis. For the deficiency of liver-yin and kidney-yin, tooth mobility, poliosis, dizzy ear toot, waist kneeAching and limp, YinXuXueRe haematemesis, bleeding from five sense organs or subcutaneous tissue, hematuria, bloody flux, metrostaxis, traumatism and bleeding.
Embodiment 1 cures mainly atherosclerotic Chinese medicine composition, is mainly prepared from (every part by following bulk drugs10g): 8 parts of selfheals, 10 parts, buckwheat, 7 parts of riparian greenbrier root and rhizomes, 5 parts of hawthorn, 7 parts of kwangtung beautyberry stem and leafs, 6 parts of China roses, 8 parts of khas aletris herbs, mountain and sea5 parts, spiral shell, 7 parts of Hainan Ervatamia Roots, 8 parts of benbies, 9 parts of corn stigmas, 4 parts, auricularia auriculajudae, 9 parts of oriental sesame seeds, 7 parts of mother chrysanthemums, 9 parts of ecliptas. OnThe preparation method who states the decoction that cures mainly atherosclerotic Chinese medicine composition is:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, with ginger juice infiltration 18 minutes, take out, slow fire dries;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 15 minutes, taking-up is placed inIn steamer, steam 20 minutes with vinegar water, taking-up is dried;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerThe decocting that material medicine quality is 7 times boils to boiling, and turn little fire and continue to decoct 28 minutes, filtering and collecting filter liquid, filter residue is stand-by;
(5) the made bulk drug of step (1) (2) (3) is mixed with the last dregs of a decoction of step (4), add water and again decoct 20 minutes, filterObtain filtrate, and mix with step (4) gained filtrate, obtain decoction.
Embodiment 2 cures mainly atherosclerotic Chinese medicine composition, is mainly prepared from (every part by following bulk drugs10g): 14 parts of selfheals, 15 parts, buckwheat, 12 parts of riparian greenbrier root and rhizomes, 11 parts of hawthorn, 13 parts of kwangtung beautyberry stem and leafs, 10 parts of China roses, khas aletris herb 13Part, 12 parts of lance asiabell roots, 14 parts of Hainan Ervatamia Roots, 12 parts of benbies, 15 parts of corn stigmas, 10 parts, auricularia auriculajudae, 16 parts of oriental sesame seeds, mother chrysanthemum 15Part, 13 parts of ecliptas. The preparation method of the above-mentioned granule that cures mainly atherosclerotic Chinese medicine composition is:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, with ginger juice infiltration 18 minutes, take out, slow fire dries;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 15 minutes, taking-up is placed inIn steamer, steam 20 minutes with vinegar water, taking-up is dried;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerThe decocting that material medicine quality is 7 times boils to boiling, then adds the made bulk drug of step (1) (2) (3), and turn little fire and continue to decoct 24 minutes,Filtering and collecting filter liquid;
(5) heating of step (4) gained filtrate is condensed into cream clearly, adds auxiliary material cane sugar powder to mix, make softwood, be pressed through 18Object screen cloth, granulation, dries whole grain, and sterilizing encapsulation, obtains granule.
Model case: xxx, the male sex, 51 years old. Main suit: paroxysmal chest pain, with n and V symptom; Medical history: patientBefore half a year, started to occur chest pain, have girdle sensation, continue 2-4 minute at every turn, be paroxysmal, when outbreak, without obvious inducement, stopAfter breath, can alleviate, overwork in the recent period, attack times increases, admission examination, and color ultrasound shows that coronary artery has atheromatous plaque, bloodFlow velocity declines, and is diagnosed as coronary atherosclerosis.
Once took western medicine, symptom makes moderate progress, and Relapse rate after drug withdrawal recommends to take this example gained particle through peopleAgent, each 2-3g, warm boiled water, one day twice, two 15 days is a course for the treatment of, patient took after the course for the treatment of, pectoralgia diseaseShape is alleviated, and attack times declines gradually, adheres to taking after two courses for the treatment of, and uncomfortable disease is all eliminated, and check shows that atheromatous plaque is brightAobvious minimizing, consolidates again a course for the treatment of, and all diseases of patient disappear entirely, follow up a case by regular visits in a year and a half, and the state of an illness does not recur.
Embodiment 3 cures mainly atherosclerotic Chinese medicine composition, is mainly prepared from (every part by following bulk drugs10g): 10 parts of selfheals, 11 parts, buckwheat, 9 parts of riparian greenbrier root and rhizomes, 7 parts of hawthorn, 9 parts of kwangtung beautyberry stem and leafs, 7 parts of China roses, 9 parts of khas aletris herbs, mountain and sea7 parts, spiral shell, 9 parts of Hainan Ervatamia Roots, 9 parts of benbies, 11 parts of corn stigmas, 6 parts, auricularia auriculajudae, 11 parts of oriental sesame seeds, 9 parts of mother chrysanthemums, 10 parts of ecliptas.The preparation method of the above-mentioned capsule that cures mainly atherosclerotic Chinese medicine composition is:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, with ginger juice infiltration 18 minutes, take out, slow fire dries;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 15 minutes, taking-up is placed inIn steamer, steam 20 minutes with vinegar water, taking-up is dried;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerThe decocting that material medicine quality is 7 times boils to boiling, then adds the made bulk drug of step (1) (2) (3), and turn little fire and continue to decoct 24 minutes,Filtering and collecting filter liquid;
(5) spraying drying steps (4) gained filtrate, will be dried thing and pulverize 125 mesh sieves, make medicinal powder, be packed in capsule,Obtain capsule.
Model case: xxx, women, 62 years old. Medical history: patient drinks and smoking throughout the year, and habits and customs are poor, has hypertensionAnd high fat of blood, because vomitting to examination in hospital without obviously inducement appearance is dizzy, found cerebral atherosclerosis, beginning after going home last yearThe western drugs such as Aspirin, symptom alleviates to some extent, but just occurs uncomfortable disease after drug withdrawal, and patient is very worried.
Recommend to take this example gained capsule through people, each 2-3 grain, warm boiled water, one day twice, two 15 days isA course for the treatment of, patient took after the course for the treatment of, and uncomfortable disease obviously alleviates, and blood pressure and blood fat start to decline, and adhere to taking three treatmentsJourney, patient returns institute's check, and cerebral atherosclerosis is clearly better, and velocity of blood flow is accelerated, and continues to take after two courses for the treatment of, and patient fullys recover from an illnessMore, each index normal, followed up a case by regular visits in 1 year, and the state of an illness does not recur.
Embodiment 4 cures mainly atherosclerotic Chinese medicine composition, is mainly prepared from (every part by following bulk drugs10g): 12 parts of selfheals, 14 parts, buckwheat, 10 parts of riparian greenbrier root and rhizomes, 9 parts of hawthorn, 11 parts of kwangtung beautyberry stem and leafs, 9 parts of China roses, 12 parts of khas aletris herbs,10 parts of lance asiabell roots, 12 parts of Hainan Ervatamia Roots, 11 parts of benbies, 13 parts of corn stigmas, 8 parts, auricularia auriculajudae, 14 parts of oriental sesame seeds, 13 parts of mother chrysanthemums, China ink12 parts, drought lotus. The preparation method of the above-mentioned soft extract that cures mainly atherosclerotic Chinese medicine composition is:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, with ginger juice infiltration 18 minutes, take out, slow fire dries;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 15 minutes, taking-up is placed inIn steamer, steam 20 minutes with vinegar water, taking-up is dried;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerThe decocting that material medicine quality is 7 times boils to boiling, and turn little fire and continue to decoct 24 minutes, filtering and collecting filter liquid, filter residue is stand-by;
(5) the made bulk drug of step (1) (2) (3) is mixed with the last dregs of a decoction of step (4), add water and again decoct 15 minutes, filterFiltrate, and mixes with step (4) gained filtrate, heat that to be concentrated into relative density be 1.12 clear cream (75 DEG C), obtain soft extractsAgent.
Model case: xxx, the male sex, 45 years old. Medical history: before patient half a year, lower limb atherosclerosis, clinical table are found in health check-upNow for Charcot's syndrome, numbness of lower limbs is sent out cool, and Foot arteries disappearances of beating, once took many western medicines, and symptom is improved and failed to understandAobvious, Relapse rate or increase the weight of after drug withdrawal, finds tcm methods treatment then.
Take upon somebody's introduction this example gained soft extract, each 6-10g, warm boiled water, one day twice, two 15 days isA course for the treatment of, patient took after the course for the treatment of, and lower limb exercise is clearly better, and numbness is sent out cool and waited remission, adhere to taking threeAfter the course for the treatment of, check atherosclerosis is eliminated substantially, and patient's physique strengthens, and health recovery from illness, followed up a case by regular visits in half a year, and the state of an illness is not multipleSend out.
Embodiment 5 cures mainly atherosclerotic Chinese medicine composition, is mainly prepared from (every part by following bulk drugs10g): 11 parts of selfheals, 12.5 parts, buckwheat, 9.5 parts of riparian greenbrier root and rhizomes, 8 parts of hawthorn, 10 parts of kwangtung beautyberry stem and leafs, 8 parts of China roses, khas aletris herb10.5 parts, 8.5 parts of lance asiabell roots, 10.5 parts of Hainan Ervatamia Roots, 10 parts of benbies, 12 parts of corn stigmas, 7 parts, auricularia auriculajudae, 12.5 parts of oriental sesame seeds, open country11 parts of chrysanthemums, 11 parts of ecliptas. The preparation method of the above-mentioned decoction that cures mainly atherosclerotic Chinese medicine composition is:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, with ginger juice infiltration 18 minutes, take out, slow fire dries;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 15 minutes, taking-up is placed inIn steamer, steam 20 minutes with vinegar water, taking-up is dried;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerThe decocting that material medicine quality is 7 times boils to boiling, and turn little fire and continue to decoct 28 minutes, filtering and collecting filter liquid, filter residue is stand-by;
(5) the made bulk drug of step (1) (2) (3) is mixed with the last dregs of a decoction of step (4), add water and again decoct 20 minutes, filterObtain filtrate, and mix with step (4) gained filtrate, obtain decoction.
Test example 1 gained of the present invention cures mainly the clinical practice of atherosclerotic Chinese medicine composition (embodiment 5):
Choose crowd: in June, 2014-2015 year June, according to medical case history, screen atherosclerotic trouble in four hospitalsPerson's 322 examples, age 41-75 year, 57.5 ± 1.8 years old mean age, the course of disease 3 days-5 years, wherein male patient's 184 examples, women suffers fromPerson's 138 examples. All patients are all diagnosed as atherosclerotic by Doppler's color ultrasound examination.
Before test, patient is divided into two groups at random, experimental group 200 example and control group 122 examples, two groups in sex, age, diseaseThe aspect such as journey, the state of an illness is without significant difference. Experimental group is taken products obtained therefrom of the present invention, and each 200-250ml is one day twice, warmTaking, 25 days is a course for the treatment of; Control group is taken other conventional medicines (aspirin enteric coated tablet, Simvastatin sheet, Ah cutting downHis spit of fland calcium tablet etc.). Period in a medicine carries out Continuous Observation to two groups of patients, records symptom and variation.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) is effective: physique strengthens, and nervous, palpitaition, gas are tight, heartbeatSpeed, extremity numbness, myocardial ischemia, the symptom such as sleep not good enough is obviously alleviated; (2) effective: physique strengthens, nervous, palpitaition, gas are tight,The symptoms such as numbness are alleviated to some extent; (3) invalid: symptom is without changing or increasing the weight of.
Clinical effectiveness: after the taking medicine of three courses for the treatment of, the treatment results of two groups is as shown in table 1:
The effective patient of experimental group is 145 examples, and obvious effective rate is 72.5%, and effectively patient is 52 examples, and efficient is 26.0%, always effectiveRate is 98.5%; In control group, effective patient is 57 examples, and obvious effective rate is 46.7%, and effectively patient is 49 examples, and efficient is 40.2%,Total effective rate 86.9%, is starkly lower than the result for the treatment of of experimental group, illustrates that products obtained therefrom of the present invention is evident in efficacy, can effectively alleviateThe various uncomfortable disease that artery sclerosis is brought.
The Chinese medicine using in the present invention, selfheal can clearing liver-fire, and buckwheat can invigorating the spleen disappears long-pendingly, and riparian greenbrier root and rhizome can dispel the wind logicalNetwork, the hawthorn loose stasis of blood that can help digestion, kwangtung beautyberry stem and leaf can hemostasis and pain-relieving, and China rose can promoting blood circulation for regulating menstruation, and khas aletris herb can qi-restoratives arrest sweating, and lance asiabell root canSupplementing qi and nourishing yin, Hainan Ervatamia Root can be clearing heat and detoxicating, and benbie can be promoting blood circulation and removing obstruction in channels, and corn stigma can inducing diuresis to reduce edema, and auricularia auriculajudae can benefiting qi and nourishing blood, blackSesame can liver-kidney tonifying, and mother chrysanthemum can the flat liver of dispelling wind, and eclipta can cooling blood and hemostasis, and multiple medicinal material synergy, can bring into play efficientThe effects such as blood dredging collateral, liver-kidney tonifying.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious skill of the present inventionArt scheme is not limited to above-described embodiment, can also have a lot of distortion. Those of ordinary skill in the art, clear and definite public with the present invention instituteThat open or according to undoubted the obtaining of the written description of file, all should think the claimed scope of this patent.

Claims (10)

1. cure mainly atherosclerotic Chinese medicine composition, it is characterized in that, be mainly prepared from by following bulk drugs, be matterAmount part: selfheal 8-14; Buckwheat 10-15; Riparian greenbrier root and rhizome 7-12; Hawthorn 5-11; Kwangtung beautyberry stem and leaf 7-13; China rose 6-10; Khas aletris herb 8-13; Lance asiabell root 5-12; Hainan Ervatamia Root 7-14; Benbie 8-12; Corn stigma 9-15; Auricularia auriculajudae 4-10; Oriental sesame seed 9-16; Mother chrysanthemum 7-15; Eclipta 9-13.
2. as claimed in claim 1ly cure mainly atherosclerotic Chinese medicine composition, it is characterized in that selfheal 10-12; BuckwheatWheat 11-14; Riparian greenbrier root and rhizome 9-10; Hawthorn 7-9; Kwangtung beautyberry stem and leaf 9-11; China rose 7-9; Khas aletris herb 9-12; Lance asiabell root 7-10; Hainan Ervatamia Root9-12; Benbie 9-11; Corn stigma 11-13; Auricularia auriculajudae 6-8; Oriental sesame seed 11-14; Mother chrysanthemum 9-13; Eclipta 10-12(is preferredBe: selfheal 11; Buckwheat 12.5; Riparian greenbrier root and rhizome 9.5; Hawthorn 8; Kwangtung beautyberry stem and leaf 10; China rose 8; Khas aletris herb 10.5; Lance asiabell root 8.5; SingleRoot wood 10.5; Benbie 10; Corn stigma 12; Auricularia auriculajudae 7; Oriental sesame seed 12.5; Mother chrysanthemum 11; Eclipta 11).
3. the preparation method of the decoction of the Chinese medicine composition as described in as arbitrary in claim 1-2, is characterized in that, step is as follows:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, infiltrate 12-24 minute with ginger juice (preferred: to infiltrate 16-20 minute; Be more preferably: infiltrate 18 minutes), take out slow fireDry;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), take out and be placed in steamer, to steam 20 minutes with vinegar water, taking-up is dried in the airDry;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerMaterial medicine quality 6-8 water (preferred: the water that adds 7 times of boiled bulk drug quality) doubly decocts to boiling, and turn little fire and continue to decoct,Filtering and collecting filter liquid, filter residue is stand-by;
(5) the made bulk drug of step (1) (2) (3) is mixed with the last dregs of a decoction of step (4), add water and again decoct 20 minutes, filterObtain filtrate, and mix with step (4) gained filtrate, obtain decoction.
4. the preparation method of Chinese medicine composition decoction as claimed in claim 3, is characterized in that, the little fire of step (4) continues to decoctBoil 22-34 minute (preferably: little fire continues to decoct 26-30 minute; Be more preferably: little fire continues to decoct 28 minutes).
5. the preparation method of the granule of the Chinese medicine composition as described in as arbitrary in claim 1-2, is characterized in that, step asUnder:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, infiltrate 12-24 minute with ginger juice (preferred: to infiltrate 16-20 minute; Be more preferably: infiltrate 18 minutes), take out slow fireDry;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), take out and be placed in steamer, to steam 20 minutes with vinegar water, taking-up is dried in the airDry;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerMaterial medicine quality 6-8 water (preferred: the water that adds 7 times of boiled bulk drug quality) doubly decocts to boiling, then adds step (1)(2) (3) made bulk drug, turns little fire and continues to decoct 20-28 minute (preferably: continue to decoct 22-26 minute; Be more preferably:Continue to decoct 24 minutes), filtering and collecting filter liquid;
(5) heating of step (4) gained filtrate is condensed into cream clearly, adds auxiliary material cane sugar powder to mix, make softwood, be pressed through sieveNet, granulation, dries whole grain, and sterilizing encapsulation, obtains granule.
6. the preparation method of Chinese medicinal composition granules as claimed in claim 5, is characterized in that, the order of step (5) screen clothNumber is that 12-24 order is (preferred: the order number of screen cloth is 16-20 order; Be more preferably: the order number of screen cloth is 18 orders).
7. the preparation method of the capsule of the Chinese medicine composition as described in as arbitrary in claim 1-2, is characterized in that, step asUnder:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, infiltrate 12-24 minute with ginger juice (preferred: to infiltrate 16-20 minute; Be more preferably: infiltrate 18 minutes), take out slow fireDry;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), take out and be placed in steamer, to steam 20 minutes with vinegar water, taking-up is dried in the airDry;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerMaterial medicine quality 6-8 water (preferred: the water that adds 7 times of boiled bulk drug quality) doubly decocts to boiling, then adds step (1)(2) (3) made bulk drug, turns little fire and continues to decoct 20-28 minute (preferably: continue to decoct 22-26 minute; Be more preferably:Continue to decoct 24 minutes), filtering and collecting filter liquid;
(5) spraying drying steps (4) gained filtrate, will be dried thing and pulverize and sieve, and make medicinal powder, be packed in capsule, obtain glueWafer.
8. the preparation method of Chinese medicinal composition capsules agent as claimed in claim 7, is characterized in that, step (5) was pulverized 90-160 mesh sieves are (preferred: to pulverize 110-140 mesh sieve; Be more preferably: pulverized 125 mesh sieves).
9. the preparation method of the soft extract of the Chinese medicine composition as described in as arbitrary in claim 1-2, is characterized in that, step asUnder:
(1) get selfheal, buckwheat and oriental sesame seed and remove impurity, be placed in frying pan, big fire stir-fries to bulk drug surface zoom Huang, getsGo out, infiltrate 12-24 minute with ginger juice (preferred: to infiltrate 16-20 minute; Be more preferably: infiltrate 18 minutes), take out slow fireDry;
(2) get ginger and cut into slices, soak and mix thoroughly with refined honey, make sweet ginger splices, kwangtung beautyberry stem and leaf, China rose, corn stigma and mother chrysanthemum are washedClean chopping, mixes with sweet ginger splices, is placed in frying container, and slow fire stir-fries to the micro-Huang in bulk drug surface, and taking-up cools;
(3) riparian greenbrier root and rhizome, lance asiabell root and Hainan Ervatamia Root removal of impurities are cleaned, be cut into sheet, add strong brine to infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), take out and be placed in steamer, to steam 20 minutes with vinegar water, taking-up is dried in the airDry;
(4) hawthorn, khas aletris herb, benbie, auricularia auriculajudae and eclipta are picked up to clean impurity, be placed in non iron container, add boiled formerMaterial medicine quality 6-8 water (preferred: the water that adds 7 times of boiled bulk drug quality) doubly decocts to boiling, turns little fire and continues to decoct20-28 minute (preferred: to continue to decoct 22-26 minute; Be more preferably: continue to decoct 24 minutes), filtering and collecting filter liquid,Filter residue is stand-by;
(5) the made bulk drug of step (1) (2) (3) is mixed with the last dregs of a decoction of step (4), add water and again decoct 15 minutes, filterObtain filtrate, and mix with step (4) gained filtrate, heating is concentrated into cream clearly, obtains soft extract.
10. the preparation method of Chinese medicine composition soft extract as claimed in claim 9, is characterized in that, step (5) heating is concentrated(preferred: heating is concentrated into the clear cream that relative density is 1.10-1.14 to the clear cream that relative density is 1.08-1.16; More excellentChoosing: it is 1.12 clear cream that heating is concentrated into relative density).
CN201510758584.3A 2015-11-10 2015-11-10 Traditional Chinese medicine composition mainly used for treating atherosclerosis, and preparation method thereof Pending CN105596811A (en)

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CN103340933A (en) * 2013-07-23 2013-10-09 孔德新 Traditional Chinese medicine composition and application thereof in atherosclerosis treatment
CN104888133A (en) * 2015-06-23 2015-09-09 包晓娜 Traditional Chinese medicine composition for treatment of coronary heart disease
CN104922504A (en) * 2015-05-29 2015-09-23 张慧玲 Vinegar beverage for treating atherosclerosis and preparation method thereof

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CN101835483A (en) * 2007-08-10 2010-09-15 阿费里斯股份公司 Atherosclerosis therapy
CN103340933A (en) * 2013-07-23 2013-10-09 孔德新 Traditional Chinese medicine composition and application thereof in atherosclerosis treatment
CN104922504A (en) * 2015-05-29 2015-09-23 张慧玲 Vinegar beverage for treating atherosclerosis and preparation method thereof
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