CN105286986B - Catheter ablation device and its electrode radio-frequency ablation catheter - Google Patents
Catheter ablation device and its electrode radio-frequency ablation catheter Download PDFInfo
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Abstract
The present invention relates to a kind of electrode radio-frequency ablation catheter, including circular segment and multiple electrodes.Circular segment is located at the distal end of catheter, there is a fluid perfusion channel in the circular segment.Multiple electrodes compartment of terrain is arranged in the circular segment, multiple apertures flowed out for fluid is offered on each electrode, and multiple aperture is connected by fill orifice with the fluid perfusion channel.Wherein, if a diameter of d (n) of the fill orifice corresponding to each electrode, n is electrode sequence number and, then d (n) with n increase increase bigger closer to catheter tip n.By this design, the flow difference of each fill orifice can be caused to reduce, so as to which the flow of each fill orifice be allowed to tend to be uniform.
Description
Technical field
The present invention relates to a kind of conduit, more particularly, to a kind of electrode radio-frequency ablation catheter.
Background technology
Radio frequency ablation catheter is a kind of electrophysiologicalcatheter catheter, it is widely used in treating arrhythmia cordis in recent years.It is general next
It says, conduit includes two functions of mapping electric signal and RF ablation.Conduit enter it is intracardiac after, first to electric signal into rower
It surveys, determines that abnormal access or abnormal electric shock are moved a little, ablation isolation is carried out to these aberrant electrical signals accesses later, so as to reach
The purpose for the treatment of.
Atrial fibrillation is a kind of common arrhythmia cordis, is that cardiac muscle loses normal and regular diastole campaign, and instead
Quick and uncoordinated faint wriggling, so as to which atrium be made to lose normal contraction.1997, cardiology professor meter Xie Era
Yi Sagaier etc. proposes that the genesis mechanism of atrial fibrillation is mainly the triggering of the fast electric excitement from pulmonary vein sleeve.Disappeared by radio frequency
Dissection connection of the pulmonary vein with atrium or electrical conduction relationship is isolated in the method melted, and can achieve the purpose that treatment.
In traditional radiofrequency ablation therapy, the distal end (one end for being used for implementing operation) of ablation catheter is single electrode,
Dotted ablation stove is generated after ablation.If forming linear ablation stove, can only slowly be dragged during ablation.It examines
Consider the lasting bounce of art cardiac, it is very high to form requirement of effective linear ablation stove to patient, and cannot often be formed
Continuous ablation stove, so as to cause the failure of isolation.The side that the remote design of ablation catheter is arranged into multi-electrode is proposed thus
Formula.These electrodes are typically alternatively arranged circlewise.In treatment, multiple electrodes jointly melt orifices of pulmonary veins, you can
Obtain cricoid ablation stove.
In ablation procedure, cooling is irrigated to electrode can significantly increase safety and the efficiency of ablation.In reality
In the application of border, improve how the efficiency of perfusion, such as how to make the flow that aperture is discharged on electrode identical, how to use minimum stream
Best cooling-down effect etc. is measured, is one and mainly considers the problems of.In ablation catheter of the distal end for single electrode,
Have by the way that electrode, guide-tube structure optimizes the scheme to improve perfusion effect.But it is multi-electrode arrangement in distal end
In ablation catheter, also lack the design that can improve perfusion effect.
Invention content
The technical problems to be solved by the invention are to provide a kind of electrode radio-frequency ablation catheter, have improved perfusion effect
Fruit.
The present invention is to solve above-mentioned technical problem and the technical solution adopted is that a kind of electrode radio-frequency ablation catheter, including ring
Shape section and multiple electrodes.Circular segment is located at the distal end of catheter, there is a fluid perfusion channel in the circular segment.Multiple electrodes compartment of terrain
It is arranged in the circular segment, multiple apertures flowed out for fluid is offered on each electrode, and multiple aperture passes through fill orifice
It is connected with the fluid perfusion channel.Wherein, if a diameter of d (n) of the fill orifice corresponding to each electrode, n is electrode sequence number and gets over
Bigger close to catheter tip n, then d (n) increases with n and is increased.
In one embodiment of this invention, the adjustable extent of the diameter of the circular segment is between 10-40mm.
In one embodiment of this invention, electrode sum is between 4-10.
In one embodiment of this invention, the small hole number on each electrode is 5-100.
In one embodiment of this invention, each hole diameter on each electrode is between 0.03-0.3mm.
In one embodiment of this invention, the quantity of the fill orifice corresponding to each electrode is 1-3.
In one embodiment of this invention, the diameter of each fill orifice is between 0.1-0.6mm.
In one embodiment of this invention, each electrode corresponds to a fill orifice, and the uniform diameter of each fill orifice is incremented by.
In one embodiment of this invention, each electrode corresponds to a fill orifice, and the diameter d (n) of each fill orifice=A+Bn+
Cn2, wherein
A=A1-A2*N, A1 are between 1.07~1.09, and A2 is between 0.02~0.03；
B=B1-B2*N, B1 are between 0.08~0.10, and B2 is between 0.001~0.003；
C=C1*N+C2, C1 are between 0.0001~0.001, and C2 is between 0.0001~0.001；
N is the sum of electrode.
In one embodiment of this invention, at least part electrode corresponds to 2 fill orifices.
In one embodiment of this invention, the electrode of corresponding 2 fill orifices is located at catheter tip.
The present invention separately proposes a kind of catheter ablation device, including multielectrode recoding ablation catheter as described above.
The present invention due to using the technology described above, be allowed to compared with prior art, by the diameter to each fill orifice into
Row optimization, can cause the flow difference of each fill orifice to reduce, so as to which the flow of each fill orifice be allowed to tend to be uniform.
Description of the drawings
For the above objects, features and advantages of the present invention can be clearer and more comprehensible, below in conjunction with attached drawing to the tool of the present invention
Body embodiment elaborates, wherein：
Fig. 1 shows the catheter ablation device of one embodiment of the invention and its radio frequency ablation catheter schematic diagram.
Fig. 2 shows the circular segment schematic diagrames of the radio frequency ablation catheter of one embodiment of the invention.
Fig. 3 shows the electrode structure of the circular segment of one embodiment of the invention.
Fig. 4 shows the axial section of the circular segment of one embodiment of the invention.
Fig. 5 shows the circular segment longitudinal section view of one embodiment of the invention.
Fig. 6 shows the fill orifice schematic diagram of the circular segment of one embodiment of the invention.
Fig. 7 shows the fill orifice schematic diagram of the circular segment of another embodiment of the present invention.
Fig. 8 shows the circular segment longitudinal section view of another embodiment of the present invention.
Fig. 9 A are that the radio frequency ablation catheter of the embodiment of the present invention enters left atrial ablation schematic diagram.
Fig. 9 B are the continuous cricoid ablation stoves that the radio frequency ablation catheter of the embodiment of the present invention is formed in orifices of pulmonary veins.
Specific embodiment
Theme claimed is described referring now to attached drawing, refers to phase using identical reference label in whole attached drawings
Same element.In the following description, for the sake of explanation, numerous details be set forth to provide to theme claimed
Comprehensive understanding.It will be apparent, however, that these themes can not also be implemented using these details.
The embodiment of the present invention describes a kind of catheter ablation device and its radio frequency ablation catheter, by the excellent of fill orifice
Change design to improve perfusion effect.
Fig. 1 shows the catheter ablation device of one embodiment of the invention and its radio frequency ablation catheter schematic diagram.With reference to 1 institute of figure
Show, ablating device 100 has radiofrequency melting instrument 110, buttock line 120, operation handle 130, intrusion pipe 140 and ablation catheter 150.
Radiofrequency melting instrument 110 is connected to operation handle 130 by buttock line 120, with by operation handle 130 on ablation catheter 150
Electrode provides energy.Intrusion pipe 140 is also connected to operation handle 130, is carried by operation handle 130 to 150 distal end of ablation catheter
For perfusion liquid, electrode perfusion is given in ablation.In addition, ablation catheter 150 is connected to operation handle 130, and in operation handle
Ablative surgery is carried out under 130 operation.
With continued reference to shown in Fig. 1, ablation catheter 150 includes main body 151, extended segment 152 and circular segment 153.Main body
151 one end are connected to operation handle 130, other end connection extended segment 152.Circular segment 153 is connected in the end of extended segment 152.
In this way, main body 151, extended segment 152 and circular segment are sequentially connected, one section of complete conduit is formed.
In an embodiment of the present invention, the material of ablation catheter 150 is generally made by polyurethane (TPU) material, but also may be used
To be made by other thermoplasticity materials, such as nylon elastomer (PEBAX).The caliber of ablation catheter 150 does not have particular requirement, but
It is usually no more than 9Fr (3Fr=1mm).
Fig. 2 shows the circular segment schematic diagrames of the radio frequency ablation catheter of one embodiment of the invention.Refering to what is shown in Fig. 2, circular segment
153 is approximate rounded, but is not to be closed completely, but by distal end of catheter natural torsion into substantially closed shape.It is cyclic annular
The diameter of section 153 can be adjusted by joystick 130.For example, diameter range is 10-40mm.
154 compartment of terrain of multiple electrodes is arranged in circular segment 153.The shape of circular segment 153 is conformed to, these electrodes 154
Thus also substantially arrange circlewise.In an embodiment of the present invention, the quantity of electrode can be 4-10.The length of electrode can be
2-4mm, preferably 3mm, the arrangement pitch between electrode and electrode can be 3-10mm, preferably 7mm.
Fig. 3 shows the electrode structure of the circular segment of one embodiment of the invention.With reference to refering to what is shown in Fig. 3, having on electrode 154
Multiple apertures 1541 are discharged for being perfused, and the diameter of aperture is between 0.03-0.3mm, preferably 0.08mm.Small hole number can
It is 5-100, preferably 20.
Fig. 4 shows the axial section of the circular segment of one embodiment of the invention.Fig. 5 shows the ring-type of one embodiment of the invention
Section longitudinal section view.First chamber 1501, second chamber 1502, the are equipped with reference to shown in Figure 4 and 5, in radio frequency ablation catheter 150
Three chambers 1506 and the 4th chamber 1508.
First chamber 1501 is perfusion channel, for establishing the channel of electrode perfusion.First chamber 1501 passes through fill orifice
1510 connect with electrode 154.When there is water perfusion in the external world, water enters electrode 154 through first chamber 1501, fill orifice 1510, then
It is flowed out by the aperture 1541 on electrode 154.
Sizing line 1503 and annular constrictions line 1504 are placed in second chamber 1502.The material of sizing line 1503 is preferably nickel
Titanium promise, can shape in advance circularizes or helical annular, and being put in this way after chamber can be such that circular segment 153 circularizes or helical annular.
Sizing line 1503 is placed in annular constrictions line 1504 in protection pipe 1505.The material of protection pipe 1505 can be polyimides
(PI) or polytetrafluoroethylene (PTFE) (PTFE).
Electrode cable 1507 is placed in third chamber 1506.It is punched between third chamber 1506 and electrode 154, electrode cable
1507 are welded by hole and electrode 154.After connection, closed with glue or epoxy resin device to hole.Here, the size in hole can lead to
Cross electrode cable 1507.
The conducting wire 1509 of magnetic inductor (not shown) is placed in 4th chamber 1508.Here, magnetic inductor can be positioned over
The distalmost end of circular segment 153, for identifying the position of conduit in treatment.
In the present embodiment, a diameter of 0.5-1 millimeters of first chamber 1501 are preferably 0.8 millimeter.The other three chamber
Diameter do not require specifically, the space of each chamber requirement cable can be placed.
It can be seen that electrode 154 and the connection diagram of circular segment 153 from Fig. 4 and Fig. 5.Electrode 154 is placed on circular segment
Outside 153.Electrode 154 can have the protrusion 154a in center and the contact site 154b of both sides.The contact site that electrode 154 passes through both sides
154b is contacted with circular segment 153.It can be at the edge of contact site 154b and 153 intersection gluing of circular segment, to be fixed in
In circular segment 153.The aperture for perfusion of electrode 154 is then distributed in protrusion 154a, as shown in Figure 3.
As shown in figure 4,154 fixed position of electrode corresponds to fill orifice 1510.Water in first chamber 1501 can be through perfusion
Hole 1510 enters electrode 154, then is sprayed from each aperture of electrode 154.In order to improve perfusion effect, the embodiment of the present invention pair
The size of fill orifice at each electrode optimizes.It summarily says, each electrode can be corresponding with fill orifice (Fig. 4 examples 1
It is a).If electrode sequence number is n, and bigger closer to catheter tip n.With reference to figure 2, the electrode sequence number close to catheter tip is 10,
Therefore electrode is marked as 154_10, and in the beginning of conduit circular segment, electrode sequence number 1.In other words, it is opened from the beginning of circular segment
Begin, electrode sequence number 1,2,3 ..., n.N can be 4-15.In addition, the overall diameter of the fill orifice corresponding to each electrode is set as d (n),
Then d (n) increases with n and is increased.It should be pointed out that this increase is not strictly monotone increasing, on the contrary, the filling of adjacent electrode
The overall diameter of orifice can be equal or almost equal.
Here, diameter r can with the increase of electrode sequence number uniform increments, can also with the increase of electrode sequence number and
It is non-homogeneous incremental.For non-homogeneous be incremented by, under the implementation form for corresponding to a fill orifice in each electrode, each filling is had been found that
The diameter r and electrode sequence number n of orifice substantially meet binomial relationship, then the uniform flow degree at each fill orifice is more preferably.
Specifically, diameter d (n)=A+Bn+Cn2, wherein A, B, C is the variable related with electrode sum N, and n is electrode
Serial number.Further, A, B, C and N meet following relationship：
A=A1-A2*N, A1 are between 1.07~1.09, and A2 is between 0.02~0.03；
B=B1-B2*N, B1 are between 0.08~0.10, and B2 is between 0.001~0.003；
C=C1*N+C2, C1 are between 0.0001~0.001, and C2 is between 0.0001~0.001.
During variables A is obtained, a value is obtained from the respective range of A1, A2 as constant A1, A2, with reference to electricity
Extremely sum acquires N.Similarly, B, C are acquired.It then can be in the hope of the corresponding perfusion bore dia d (n) of each electrode sequence number.
Analog result shows the diameter for meeting above-mentioned relation, can control the flow standard variance of each fill orifice 1
It is interior.If the uniform diameter of each fill orifice is incremented by, the flow standard variance of each fill orifice generally can more than 1 1.5 with
Under.In contrast, if the diameter of each fill orifice is identical, the flow standard variance of each fill orifice can be more than 2.
Fig. 6 shows the fill orifice schematic diagram of the circular segment of one embodiment of the invention.Refering to what is shown in Fig. 6, the mark of 10 electrodes
Number it is respectively 154_1,154_2,154_3 ..., 154_10, correspondingly fill orifice label is respectively 1510_1,1510_2,
1510_3,...,1510_10.If the diameter difference r (1) of each fill orifice, r (2), r (3) ..., r (10), then have：r(1)≤r
(2)≤r(3)≤,...,≤r(10).That is, electrode sequence number is bigger, then the diameter of fill orifice is smaller.
The advantage of this design can be cited from hydrodynamics.According to fluid mechanics equation, Bernoulli equation：
In the pressure that this P is fill orifice, ρ is fluid density, and v is the flow velocity at fill orifice, and ω is frictional dissipation.
In this example, to Bernoulli equation can be used at fluid inlet and any fill orifice, i.e.,：
Best perfusion effect in order to obtain, the outflow total amount of each fill orifice should be equal, i.e.,：
Q1=Q2=Q3...=Q10；
And under same traffic, the static pressure that each electrode gives fill orifice is identical, i.e.,：
P1=P2=P3...=P10
According toR is perfusion pore radius,
Because ω1＜ ω2... ＜ ω10,
Therefore, if r (1)≤r (2)≤r (3)≤... ,≤r (10), can offset this variation tendency of w, make
And the flow at fill orifice be intended to it is equal.
The result simulated in software with reference to specific example illustrate the present invention implementation result.Use software
Flow simulation are simulated in solidworks, and the exit static pressure of fill orifice is set as 103997.52Pa, inlet flow rate
It is set as 60ml/min.The following table 1 shows the perfusion pore diameter size and discharge relation of circular segment.
Table 1
As shown in Table 1, when the diameter of each fill orifice all identical (example 1), discharge rate is slower and slower, each perfusion
The flow in hole is all uneven, and whole variance reaches 2.23, it is impossible to reach uniform perfusion effect.If adjust each fill orifice
Diameter, gradually increased from water inlet to end, then the uniformity of groundwater increment is significantly improved, whole in several example 2-6
Variance is respectively 1.34,0.82,0.71,0.64 and 0.41.The wherein example incremental for uniform diameter of example 2, example 3-6 is straight
The non-homogeneous incremental example of diameter.Therefore diameter is uniform increments or non-homogeneous incremental, and it is equal can to significantly improve flow
Even property.Also, it if according to non-homogeneous incremental manner, improves discharge uniformity and more breathes out.For example, non-homogeneous incremental manner
Under, mutual diameter proportion is r1:r2:r3:r4:r5:r6:r7:r8:r9:R10=1:(1.00-1.05):(1.10-
1.13):(1.14-1.20):(1.25-1.35):(1.35-1.40):(1.51-1.60):(1.70-1.80):(1.85-
1.95):(2.00-2.20)。
It is highly preferred that for r1:r2:r3:r4:r5：r6:r7:r8:r9:R10=1:1.08:1.19:1.35:1.38:
1.577:1.73:1.92:2。
Also, the design of diameter is preferably while consider flow velocity, since it is desirable that the water flowed out from hole has larger flow velocity, shape
Into water spray effect.The following table 2 shows the perfusion pore diameter size and flow velocity relation of circular segment.
Table 2
In above-mentioned each example, example 3 has relatively large flow velocity 0.61m/s in the 10th hole of end, therefore is
Better choice.
In another embodiment of the invention, the quantity of fill orifice can be 9, and correspondingly diameter design is as follows：
Table 3
The respectively same diameter of examples detailed above 1,2,3, the design of uniform increments diameter and uneven incremental diameter, three kinds
Corresponding flow variance be respectively 4.14,0.80 and 0.40.It can be seen that diameter is uniform increments or non-homogeneous passs
Increase, can significantly improve discharge uniformity.In contrast, irregularly incremental diameter has more preferable discharge uniformity.Citing
For, under non-homogeneous incremental manner, diameter ratio is：(1-1.65).3:(1.20-1.30):(1.35-1.45):(1.-1.95):
(1.90-2.30):(2.10-2.60)0):(2.55-2.65):(2.8-3.1)。
In the case that the following table 4 shows that the quantity of the fill orifice of circular segment is 9, pore diameter size and flow velocity relation is perfused.
Table 4
In above-mentioned each example, example 2-3 be respectively provided in the 9th hole of end relatively large flow velocity 0.78m/s and
0.60m/s, therefore be all feasible selection.
In another embodiment of the invention, the quantity of fill orifice can be 7, and correspondingly diameter design is as follows：
Table 5
Examples detailed above sample 1 is the design of same diameter, and variance 4.20, sample 2,3 is distinguished uneven incremental straight
The design of diameter, flow variance are respectively 0.43 and 0.48.It can be seen that diameter is uniform increments or non-homogeneous incremental,
Discharge uniformity can be significantly improved.In contrast, irregularly incremental diameter has more preferable discharge uniformity.For example,
Under non-homogeneous incremental manner, diameter ratio is：(1-1.65).3:(1.20-1.30):(1.35-1.45):(1.-1.95):(1.90-
2.30):(2.10-2.60)0):(2.55-2.65):(2.8-3.1)。
In the case that the following table 6 shows that the quantity of the fill orifice of circular segment is 7, pore diameter size and flow velocity relation is perfused.
Table 6
In above-mentioned each example, example 2-3 be respectively provided in the 7th hole of end relatively large flow velocity 1.05m/s and
0.78m/s, therefore be all feasible selection.In contrast, in the non-homogeneous incremental example of diameter, flow velocity is more preferably.
In another embodiment of the invention, the quantity of fill orifice can be 4, and correspondingly diameter design is as follows：
Table 7
Examples detailed above sample 1 is the design of same diameter, and variance 3.31, sample 2,3 is distinguished uneven incremental straight
The design of diameter, flow variance are respectively 1.11 and 0.27.It can be seen that diameter is uniform increments or non-homogeneous incremental,
Discharge uniformity can be significantly improved.In contrast, irregularly incremental diameter has more preferable discharge uniformity.
The present invention does not limit each electrode and corresponds to a fill orifice.That is, each electrode can correspond to more fillings
Orifice, such as 2-3 fill orifice.Especially, if one or more electrodes of catheter tip use multiple fill orifices, Ke Yirang
Flow between the fill orifice of each electrode is more uniformly distributed, and can improve the fill orifice flow velocity of the electrode of distal end of catheter.
When the fill orifice on an electrode is replaced with multiple fill orifices, can implement according to following conversion relations：
πR2=n π r2(diameter when R is single fill orifice, can be obtained by above-mentioned calculating formula, and n is filled when being multiple fill orifices
The number of orifice, the diameter of fill orifice during r=more a fill orifices)
The situation that partial electrode corresponds to 2 fill orifices is set forth below.
Fig. 7 shows the fill orifice schematic diagram of the circular segment of another embodiment of the present invention.Refering to what is shown in Fig. 7,10 electrodes
Label is respectively 254_1,254_2,254_3 ..., 254_10, and correspondingly fill orifice label is respectively 2510_1,2510_2,
2510_3,...,2510_10.If the gross area difference s1, s2, s3 ..., the s10 of each fill orifice, then have：s1≤s2≤s3
≤,...,≤s10.That is, electrode sequence number is bigger, then the gross area of fill orifice is smaller.Particularly, the one of distal end of catheter
On a or several electrodes, such as electrode 254_7,254_8,254_9 and 254_10 carry out diplopore design, the gross area of fill orifice
As s7, s8, s9, s10.The following table 8 shows the perfusion pore diameter size and discharge relation of circular segment.
Table 8
The flow that example 1 above -3 can allow between fill orifice is more uniformly distributed (whole variance<0.6) 8, are shown in Table.In addition,
It can ensure under identical input flow rate (60ml/min) can have good water spray effect, that is, spray using the design of holes
The rate gone out is big.The following table 9 shows the perfusion pore diameter size and flow velocity relation of circular segment.
Table 9
Contrast table 9 and table 1, even if in the most slow hole 10 of flow velocity, also there is more than 0.83m/s as can be seen that under diplopore design
Flow velocity, hence it is evident that higher than single hole design lower opening 10 flow velocity.
For the situation of 10 electrodes, if carrying out diplopore design, the total area ratio of each electrode lower opening should be in s (1):s
(2):s(3):s(4):s(5):s(6):s(7):s(8):s(9):S (10)=1:(1-1.2):(1.15-1.30)：(1.35-
1.50):(1.6-2):(1.9-2.1):(2.15-2.40):(2.35-2.70):(2.70-2.95):(2.85-2.95)；It is preferred that
Ground, s (1):s(2):s(3):s(4):s(5):s(6):s(7):s(8):s(9):S (10) is 1:1:1.17:1.36:1.56:
2.01:2.18:2.34:2.72:2.92。
It is appreciated that according to flow velocity needs, can begin to design using diplopore in smaller electrode sequence number.Such as from
6 electrodes start, and are just designed using diplopore.It is of course also possible to diplopore is begun to use to design from the electrode sequence number of bigger.Such as from
8th electrode starts, and just diplopore is begun to use to design.
It is appreciated that for having an embodiment of more or less electrode, diplopore design be still it is applicable, herein not
Reinflated description.
Correspondingly, Fig. 8 shows the circular segment longitudinal section view of another embodiment of the present invention.With reference to figure 8, in a certain electrode
Corresponding two fill orifices 2510 in 254 lower sections, connect first chamber 2501.
Fig. 9 A enter the intracardiac process melted for radio frequency ablation catheter.General process is that guide sheath 910 is quiet through stock
Arteries and veins, inferior caval vein enter intracardiac, and by atrial septal puncture, guide sheath 910 enters atrium sinistrum 902 and (is located at right side in figure, left side is
Atrium dextrum 901), loop-like ablation conduit 150 enters atrium sinistrum 902 by guide sheath 150, with the help of X ray, through operation handlebar
Loop-like ablation conduit 150 is positioned over the ostium venosum cordis of pulmonary vein 903, is melted, and forms the ablation stove 920 (Fig. 9 B) of annular.It
Afterwards, other three orifices of pulmonary veins are melted successively, finally obtains the isolation of pulmonary vein.
The described radio frequency ablation catheter of the above embodiment of the present invention is compared, and is carried out by the diameter to each fill orifice excellent
Change, the flow difference of each fill orifice can be caused to reduce, so as to which the flow of each fill orifice be allowed to tend to be uniform.Also, by portion
Fill orifice is divided to carry out diplopore design, the present invention can allow the flow velocity of each fill orifice not to be substantially reduced, maintain the ejection of perfusion liquid
Effect.
Although the present invention is described with reference to current specific embodiment, those of ordinary skill in the art
It should be appreciated that above embodiment is intended merely to illustrate the present invention, can also make in the case of without departing from spirit of the invention
Go out various equivalent change or replacement, therefore, as long as to the variation of above-described embodiment, change in the spirit of the present invention
Type will be all fallen in the range of following claims.
Claims (10)
1. a kind of electrode radio-frequency ablation catheter, including：
Circular segment has a fluid perfusion channel in the distal end of catheter, the circular segment；
Multiple electrodes, compartment of terrain are arranged in the circular segment, and multiple apertures flowed out for fluid are offered on each electrode；
Wherein, fluid perfusion channel is connected with the aperture on each electrode by fill orifice, if the fill orifice corresponding to each electrode
A diameter of d (n), n are electrode sequence number and, then d (n) with n increase increase bigger closer to catheter tip n；
Wherein, each electrode corresponds to a fill orifice, and the diameter d (n) of each fill orifice=A+Bn+Cn2, wherein：A=A1-A2*N,
A1 is between 1.07~1.09, and A2 is between 0.02~0.03；B=B1-B2*N, B1 are between 0.08~0.10, B2
Between 0.001~0.003；C=C1*N+C2, C1 between 0.0001~0.001, C2 between 0.0001~0.001 it
Between；N is the sum of electrode.
2. electrode radio-frequency ablation catheter as described in claim 1, which is characterized in that the diameter of circumference can where the circular segment
Range is adjusted between 10-40mm.
3. electrode radio-frequency ablation catheter as described in claim 1, which is characterized in that electrode sum is between 4-10.
4. electrode radio-frequency ablation catheter as described in claim 1, which is characterized in that the small hole number on each electrode is 5-
100.
5. electrode radio-frequency ablation catheter as described in claim 1, which is characterized in that each hole diameter on each electrode exists
Between 0.03-0.3mm.
6. electrode radio-frequency ablation catheter as described in claim 1, which is characterized in that the diameter of each fill orifice is in 0.1-0.6mm
Between.
7. a kind of electrode radio-frequency ablation catheter, including：
Circular segment has a fluid perfusion channel in the distal end of catheter, the circular segment；
Multiple electrodes, compartment of terrain are arranged in the circular segment, and multiple apertures flowed out for fluid are offered on each electrode；
Wherein, fluid perfusion channel is connected with the aperture on each electrode by fill orifice, if the fill orifice corresponding to each electrode
A diameter of d (n), n are electrode sequence number and, then d (n) with n increase increase bigger closer to catheter tip n；
Wherein, the quantity of the corresponding fill orifice of each electrode is 1-3；When electrode correspond to 1 fill orifice when, fill orifice it is straight
Diameter d (n)=A+Bn+Cn2；When electrode corresponds to 2 fill orifices, the diameter of fill orificeWork as electrode
During corresponding 3 fill orifices, the diameter of fill orificeWherein：A=A1-A2*N, A1 between 1.07~
Between 1.09, A2 is between 0.02~0.03；B=B1-B2*N, B1 between 0.08~0.10, B2 between 0.001~
Between 0.003；C=C1*N+C2, C1 are between 0.0001~0.001, and C2 is between 0.0001~0.001；N is electrode
Sum.
8. a kind of electrode radio-frequency ablation catheter, including：
Circular segment has a fluid perfusion channel in the distal end of catheter, the circular segment；
Multiple electrodes, compartment of terrain are arranged in the circular segment, and multiple apertures flowed out for fluid are offered on each electrode；
Wherein, fluid perfusion channel is connected with the aperture on each electrode by fill orifice, if the fill orifice corresponding to each electrode
A diameter of d (n), n are electrode sequence number and, then d (n) with n increase increase bigger closer to catheter tip n；
Wherein, at least part electrode corresponds to 2 fill orifices, and the diameter of 2 fill orifices is respectively
Wherein：A=A1-A2*N, A1 are between 1.07~1.09, and A2 is between 0.02~0.03；B=B1-B2*N, B1 between
Between 0.08~0.10, B2 is between 0.001~0.003；Between 0.0001~0.001, C2 is situated between by C=C1*N+C2, C1
Between 0.0001~0.001；N is the sum of electrode.
9. electrode radio-frequency ablation catheter as claimed in claim 8, which is characterized in that the electrode of corresponding 2 fill orifices, which is located at, leads
Pipe end.
10. a kind of catheter ablation device, including such as claim 1-9 any one of them electrode radio-frequency ablation catheter.
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| CN103142304A (en) * | 2012-11-13 | 2013-06-12 | 陈绍良 | Multistage synchronous pulmonary artery radiofrequency ablation catheter |
| CN203493737U (en) * | 2013-10-15 | 2014-03-26 | 上海微创电生理医疗科技有限公司 | Medical treatment catheter and radiofrequency treatment system |
| CN203539434U (en) * | 2013-04-12 | 2014-04-16 | 上海微创电生理医疗科技有限公司 | Multi-electrode ablation catheter |
| CN204158487U (en) * | 2014-07-30 | 2015-02-18 | 上海微创电生理医疗科技有限公司 | Catheter ablation device and electrode radio-frequency ablation catheter thereof |
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| CN102274021A (en) * | 2010-04-21 | 2011-12-14 | 韦伯斯特生物官能(以色列)有限公司 | Dual-purpose lasso catheter with irrigation using circumferentially arranged ring bump electrodes |
| CN103142304A (en) * | 2012-11-13 | 2013-06-12 | 陈绍良 | Multistage synchronous pulmonary artery radiofrequency ablation catheter |
| CN203539434U (en) * | 2013-04-12 | 2014-04-16 | 上海微创电生理医疗科技有限公司 | Multi-electrode ablation catheter |
| CN203493737U (en) * | 2013-10-15 | 2014-03-26 | 上海微创电生理医疗科技有限公司 | Medical treatment catheter and radiofrequency treatment system |
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