CN105259114A - Portable acetone breath analyzer capable of realizing real-time on-line monitoring of fat burning - Google Patents
Portable acetone breath analyzer capable of realizing real-time on-line monitoring of fat burning Download PDFInfo
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Abstract
The invention discloses a portable acetone breath analyzer capable of realizing real-time on-line monitoring of fat burning. Mainly directed at the demand for real-time feedback of fat-reducing effect of fat-reducing people in diet controlling, physical exercise, drug controlling and the like, the invention provides the CRDS technology-based portable acetone breath analyzer capable of realizing real-time on-line monitoring of fat-reducing effect, i.e., fat burning, by measuring the content of the volatile organic compound (VOC) acetone in breathing components.
Description
Technical field
The present invention relates to the volatile organic compounds detection technique field in respiratory component, particularly relate to a kind of portable acetone scentometer.
Background technology
The present invention relates to a kind of portable acetone scentometer of real time on-line monitoring fat combustion.This analyser is the cavity ring down spectroscopy technology (CRDS) based on hypersensitive, high selectivity.
Mainly for fat-reducing personage keeping on a diet, in the process such as physical training and medicine control, to the demand of fat-reducing effect Real-time Feedback, and current fat-reducing effect is by the means such as measured body weight and three-dimensional measurement, by fat-reducing effect reaction instantly, thus a kind of portable acetone scentometer based on CRDS technology of the content real time on-line monitoring fat-reducing effect-fat combustion by measuring volatile organic compounds (VOCs) acetone in respiratory component can not be invented.This invention belongs to biomedical sector.
Fat basic reason is that Energy intaking exceedes energy ezpenditure.The energy supply material of origin of heat in dietary intake: protein (4kcal/g), fat (9kcal/g), carbohydrates (4kcal/g), heat exhaustion is primarily of three aspects: basic metabolism, body movement and food thermal effect.Fat-reducing belong to by the behavior reduced for the purpose of the excessive fat of human body, body weight, refer to the various method of the obese people of certain class overweight as: dancing, Yoga etc., become curve build again.Manage the improper activity that correction overweight people abnormal response causes, namely analyze the characteristic sum type of sports of overweight people's feeding behaviour by human behavior science, based on this, rationally revise the action of causeing fat.
All methods of weight-reducing are all directly or indirectly centered by heat, and efficiency index is for reducing heat.
One of difficulty of fat-reducing lacks real-time feedback.The remarkable result of making great efforts fat-reducing is not presented at instantly usually.But people are being in going on a diet or in fracture process, always wondering oneself doing whether correct or effective of unstable, intermediate state.Therefore need a kind of monitoring and the real-time instrument understanding fat-reducing effect, for understanding the fat-reducing situation of oneself, selecting the body weight control mode being applicable to oneself, such as controlling food intake dose, use class health products of losing weight, approach such as fat-reducing class medicine and physical training etc.
Acetone is fat combustion Metabolite, metabolic product in blood can enter lung by ABB, and then causing the change of expiratory air component, some specific gas concentration excreted is raised, and therefore breathing acetone and Blood ketone body have strong correlativity.The present invention measures the fat combustion situation in the content of acetone monitoring human weight loss procedures in human body respiration gas componant quickly and accurately, assesses, thus provide direction to the Weight management mode that fat-reducing personage adopts.And current fat-reducing effect is by the means such as measured body weight and three-dimensional measurement, by fat-reducing effect reaction instantly, real-time fat-reducing effect assessment can not be carried out, the direction of body weight supervision cannot be provided.Having in the market to release utilizes test paper to measure urine ketone to measure the method for fat-reducing effect, and the method detecting urine ketone can only provide half measures of quantization, cannot provide reference accurately, and the method can not carry out real-time online detection.
Summary of the invention
The present invention is directed to the limitation (as introduced) of assessment fat-reducing effect method at present above, invention one can breathe the scentometer of acetone level by AT measuring method (breast rail method) real-time online measuring, this instrument can realize the real-time Measurement accuracy to human body respiration acetone concentration, direct display fat combustion situation, and data syn-chronization can be uploaded network and be presented at various terminal electronic device, this invention needs for fat-reducing personage and other crowd understanding fat combustion situation in time, the fat combustion situation of oneself can be grasped in fact in time, timely adjustment body weight supervision scheme, and then its fat-reducing effect is significantly improved.This instrument can be used for fat-reducing personage at home, gymnasium, Weight management center, the place such as hospital and community sport's exercise center, the personage being convenient to need understands oneself fat combustion situation in time.
The technical scheme adopted for realizing object of the present invention is: adopt current-modulation method to realize laser and be coupled with resonator cavity and produce with cavity-type BPM signal, also being namely coupled of laser and resonator mould is realized by the mode of periodic modulation laser diode working current, after some resonator moulds are excited, cut off its Laser output by the working current turning off laser instrument, realize the generation of cavity-type BPM signal.Such design avoids the use of the optics such as photoswitch and piezoelectric transducer and mechanical part, not only simplify system architecture, and improves stability.System is formed primarily of optical table and Electronic Control two parts: optical table part mainly comprises laser instrument, gas sample chamber (optical resonator), detector and other annex etc., and its function is the acquisition realizing spectral signal.Wherein, gas sample chamber is not only for holding gaseous sample to be measured, and it is an optical resonator especially, and its two ends are two panels high reflectivity mirror, forms a stable resonator, laser back and forth can be propagated in chamber, realize the generation of cavity ring-down spectroscopy.This optical table part is fixed on the aluminium sheet of one piece of 600mm × 250mm × 10mm (length and width are thick), can move integrally and not need to readjust light path.Consider the size of the main devices such as adopted laser instrument, gas sample chamber and detector, this optical table part can be loaded in the cartridge type pressure-resistant seal cabin of an internal diameter Φ=200mm, length L=600mm.Electronic control part comprises laser controlling power supply, vacuum pump, oscillograph and computing machine etc., main settling signal collection, display and processing capacity.Wherein, vacuum pump is used for intracavity gas sample to pump, oscillograph is for showing cavity-type BPM signal and carrying out A/D conversion to the simulating signal collected, software again by loading in computing machine carries out data processing, and these three equipment can use micropump, data collecting card and PC/104 industrial computer to replace to realize miniaturization respectively.
According to the difference of used LASER Light Source, CRDS can be divided into the pulsating wave cavity ring-down spectroscopy (Pulsed-CRDS) using pulse laser and the continuous wave-cavity ring-down spectroscopy (CW-CRDS) using continuous laser, and wavelength coverage covers ultraviolet to infrared band.According to the difference of research object and demand, the kind of laser instrument is also different, such as neodymium-doped yttrium-aluminum garnet (Nd:YAG) laser instrument, titanium-doped sapphire (Ti:sapphire) laser instrument, the dye laser of Nd:YAG laser or excimer laser pumping and optical parametric oscillator (OPO), quantum cascade laser, semiconductor laser diode, etc.
In order to realize the efficient coupling of laser and cavity modes, in general can increase as acoustooptic switch, piezoelectric transducer, optical coupling element or the device realizing similar functions etc. in CW-CRDS system.And a kind of portable acetone scentometer of real time on-line monitoring fat combustion requires that sensor bulk is little, compact conformation, Simultaneous Stabilization wants high.Complicated light path and mechanical displacement means will inevitably make the stability of analyser be affected, therefore, system have employed current-modulation method and realizes the efficient coupling of laser and cavity modes and the realization of cavity-type BPM phenomenon, its advantage to replace the optics such as photoswitch and piezoelectric transducer and mechanical displacement means, is conducive to the stability improving experimental system.
Therefore, sensor adopts diaphragm pressure sensor, for model is the micro pressure sensor of MKS870B.Pressure transducer is arranged on on optical resonator in two gas outlets, and measurement range is 0.5-1000Torr, for measuring the pressure in optical resonator.
Wherein, LASER Light Source is tunable wave length laser diode laser instrument, and coupled is a temperature and current controller, and this controller can control working temperature and the working current of laser instrument, and external modulation signal can be received, thus control the output wavelength of laser instrument.First outgoing laser beams becomes directional light via after collimating apparatus, and then by optoisolator, is coupled in the stable resonator that is made up of two sides high reflectance plano-concave catoptron.Due to the high reflectance of catoptron, therefore only have sub-fraction light can enter in resonator cavity, the laser energy of more than 99% will be reflected back.The effect of optoisolator is that laser can only unidirectionally be passed through, and avoids light feedback and causes interference to the work of laser instrument.Two-face mirror is individually fixed in the two ends of a tubular cavity, forms an airtight gas sample chamber.Detector inputs to oscillograph and digital delay/pulse signal generator after converting the light signal from other end outgoing to electric signal.Simulating signal A/D, while realizing observation signal function, is converted into digital signal by oscillograph, and transfers to computing machine to process.
Wherein, the instrument of expiratory air sample collection is that respirator mask and gas sample sack couple together by use retaining valve, during collected specimens, face shield is covered and shut up and nose areas, such expiratory air passes through this retaining valve by unidirectional, thus in collected sample sack, and by this retaining valve, person under inspection still can freely breathe.
Wherein, the photoswitch of the form such as acousto-optic, electric light is not equipped in the front end of resonator cavity, and resonator cavity does not have the devices such as piezoelectric transducer yet, and being therefore coupled of the shutoff of laser and laser and resonator cavity realizes by other means.Laser controller is when controlling laser work temperature stabilization, load a triangular modulation signal from function signal generator by the working current of laser instrument, this modulation signal changes making laser frequency (in other words wavelength) in a small scope simultaneously.Usually, this scope is greater than a free spectral range of resonator cavity.Like this, within a scan period of triangular wave, laser frequency at least twice can reach consistent with some resonance frequencies of resonator cavity, when the light intensity signal that detector catches reaches threshold value, digital delay/pulse signal generator using output pulse as enable signal to laser controller, make the working current of laser diode be in below its drive threshold electric current, laser instrument will stop Output of laser, achieve the function cutting off laser, cavity-type BPM phenomenon can be observed thereupon.Under optical maser wavelength current-modulation mode, so just achieve being coupled and the cut-out of laser of laser and resonator cavity, eliminate the device such as photoswitch and piezoelectric transducer.Such design not only makes system more succinct, and the system that improves works necessary stability in the presence of a harsh environment.Embodiment is shown in specific implementation and the sequential control of this current modulating method.The analog electrical signal sample quantization that described analog to digital converter is used for photomultiplier to produce is digital signal, carries out digital signal processing for computing machine.
Wherein, described computing machine is microcomputer general at present or video work station, for carrying out data processing.Photomultiplier detects each and declines and swing waveform and deliver to analog to digital converter, is digitized as 1000 data points and is input to computing machine.Then with a simple decaying exponential function, matching is carried out to data point, obtain the signal attenuation time.
Adopt the CW-CRDS experimental system of current-modulation scheme primarily of formations such as laser instrument and controller, optoisolator, gas sample chamber, photo-detector and current-modulation devices.
What adopt in instrument is a kind of semiconductor DFB laser diode.Form resonator cavity to realize with using minute surface in common laser instrument produce the necessary retroactive effect of laser unlike, it adopts the structure of refractive index cycle change to realize resonator cavity feedback function, also namely provides feedback by the Bragg scattering of one group of diffraction grating structure.This optical grating construction has good wavelength selectivity, and due to its structure small, therefore not only can ensure the monochromaticity of Output of laser wavelength, and can realize single longitudinal mode export.Because the Refractive Index of Material making semiconductor DFB varies with temperature, when changing its working temperature, the optical grating construction in laser instrument will change, and its output wavelength is also by corresponding change.Therefore by changing the working temperature of laser instrument, wavelength tuning can be realized.
Wherein, DFB laser diode is from Japanese NTTElectronics (NEL) company, and adopt 14 pin butterfly encapsulation, structure is very compact, as shown in Figure 2.
Fig. 3 is above-mentioned semiconductor laser diode stationary fixture, and the slot of zero insertion force and the clamp of spring make the fixing very easy with disassembling section of laser diode.The size of laser diode stationary fixture is only 32mm × 102mm × 140mm, and maximum operating currenbt can reach 2A.
Encapsulate by definition and butterfly the 14 needle tubing pin that laser diode is connected, can Current Control be provided for semiconductor laser and heat radiation is provided.This fixture provides standard interface, is convenient to be connected with semiconductor laser controller.
Semiconductor laser controller (ILXLightwave, LDC-3724C) is in fact divided into current source and temperature controller two parts function.First, it is a current source based on Microprocessor S3C44B0X, and in can be, lower powered laser diode provides the high precision electro current control of 200/500mA range, and its current control accuracy, up to 16, has high stability, low noise and other advantages.This controller takes a series of effective laser diode safeguard measure, comprises delay startup (slowstartturn-on), adjustable current limits value, output short circuit, Surge suppression protection and exports quick closedown (fastoutputshut-off) etc.Wherein, export the impact that quick closedown characteristic not only can make laser diode avoid loose contact to bring, and can ensure that producing the necessary laser of cavity-type BPM turns off fast.When realizing Current Control, this controller has three kinds of mode of operations: low bandwidth constant current mode, high bandwidth constant current mode and invariable power pattern.Wherein, constant current mode all supports that external signal is modulated, and low bandwidth constant current mode supports that external modulation signal frequency is 15KHz to the maximum, then up to 1MHz under high bandwidth mode.
Secondly, this controller is integrated with quick, a high-precision 32W temperature and controls power supply, and therefore, it is again that a temperature controls power supply.Its temperature control power supply and the power supply of current source are separated from each other.The precision of this temperature control power supply is 16 equally, and the accuracy of measurement of temperature correction sensor is 0.05 DEG C.In addition, LDC-3724C is furnished with IEEE-488 type gpib interface and Type B USB interface, is convenient to programming realization automatic remote and controls.
Laser instrument exports light, by the reflection end face in light path, the phenomenon in a part of light again reflect back into laser resonator cavity is called that light feeds back.Optical feedback effect can affect the output characteristics of laser instrument, destroys coherence and stability that laser instrument exports light.In CW-CRDS experimental system, because the catoptron forming resonator cavity has very high reflectivity (>99.9%), only have a fraction of light can incide in resonator cavity, the light of the overwhelming majority is all reflected back, and the light feedback therefore in light path is serious.Although the built-in isolation of laser diode of butterfly encapsulation is 30dB, in order to eliminate optical feedback effect further, in system, be equipped with an optoisolator in addition.This optoisolator customizes in Thorlabs company, adopts absorbing film polaroid to make, has the advantage of compact conformation.Its centre wavelength is 1625nm, clear aperature 4mm, and light transmission rate is between 81-85%, and the power-handling capability bearing continuous laser is 25W/cm
2.
Gas sample chamber forms primarily of three parts: steel tubular chamber, catoptron fixture and catoptron, and the long 500mm in steel tubular chamber, internal diameter 35mm are furnished with three air inlet/outlets.Tubular cavity surface is coated with one deck quartz, has etch-proof function.Two ends, sample chamber respectively have a catoptron fixture to be connected with the port of tubular cavity, and this catoptron fixture is used for clamping and stationary mirror.Three adjustment screw rods of catoptron fixture equipment are for adjusting mirror angle, and two-face mirror actually constitutes the resonator cavity of a CRDS system.
Like this, tubular cavity, catoptron fixture and catoptron constitute an airtight gas sample chamber jointly.One of function of this sample chamber holds gas to be analyzed, and hermetically-sealed construction can avoid external environment on the impact of analytic process, and can control gaseous sample volume by Quality control indoor gas pressure, is convenient to inverting test substance concentration; Function two, it is in fact again a resonator cavity, and be important component part in CRDS technology, laser is back and forth propagated in sample chamber, adds absorption light path, substantially increases the detection sensitivity to trace gas.Laser propagation times back and forth in resonator cavity, not only relevant with the absorption of sample, and also relevant with the reflectivity of catoptron with the stability of resonator cavity.The loss of resonator that stability is higher is less, and the raising of reflectivity can make transmitted light intensity reduce, and increases the order of reflection of light in resonator cavity.
Carry out detecting and changing into electric signal from cavity-type BPM optical signals indium gallium arsenic photodiode of resonator cavity outgoing, the wavelength response range of this detector is 700-1800nm, peak response is positioned near 1550nm, is respectively 1.05 and 0.90A/W at the Photoresponse at 1600 and 1650nm place.Detector gain 8 grades is adjustable, reaches as high as 70dB.When gain is 0dB shelves, its bandwidth value is 17MHz, rise time 21ns; When gain rises to 40dB, bandwidth is 320KHz, rise time 1.1 μ s.
The triangular wave that function signal generator exports is input in laser controller as external modulation signal, make the output light frequency of laser diode (determining according to resonator cavity free spectral range size) periodically-varied in a very little scope, when laser frequency is consistent with the resonance frequency of resonator cavity, the chamber mould of resonator cavity will be excited, laser coupled, in resonator cavity, completes being coupled of laser and resonator cavity with this.
The function of digital delay/pulse signal generator has two aspects.One, monitoring photodetector signal intensity, setting threshold value, when the signal strength increases above a threshold, sends synchronization pulse to oscillograph, gathers cavity-type BPM signal.Its two, send pulse signal as enable signal to laser controller, make laser powered sensor electric current lower than its operation threshold electric current, complete and turn off laser function.Be input in laser controller after synthesizing a road signal by a combiner from the signal of function signal generator and digital delay/pulse signal generator.
Oscillograph is used for the real-time display of cavity-type BPM signal, average and modulus (A/D) translation function.This oscillograph bandwidth 60MHz, vertical resolution 8, storage depth is 2.5K, sampling rate 1GS/s, is used for carrying out mono-exponential fit to cavity-type BPM signal like this in 1 μ s by collecting at most 1000 data points.
The software loaded in computing machine will carry out mono-exponential fit to from oscillographic cavity-type BPM digital signal, obtain cavity-type BPM time τ.
Accompanying drawing explanation
Figure 1 shows that the schematic diagram of the portable acetone scentometer of real time on-line monitoring fat combustion;
Figure 2 shows that laser structure figure;
Figure 3 shows that the fixing jig composition of semiconductor laser diode.
Figure 4 shows that the control flow chart of CW-CRDS system.
Embodiment
Below in conjunction with specific embodiment, the present invention is described in further detail.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
A kind of portable acetone scentometer of real time on-line monitoring fat combustion, comprise laser instrument 1 and laser controller 6, optoisolator 4, gas sample chamber 11, photo-detector 5 and current-modulation device, described gas sample chamber forms primarily of three parts: steel tubular chamber, catoptron fixture and catoptron.
The described long 500mm in steel tubular chamber, internal diameter 35mm, be furnished with three air inlet/outlets 3; Tubular cavity surface is coated with one deck quartz; Described gas sample chamber 11 two ends respectively have a catoptron fixture to be connected with the port of tubular cavity, and described catoptron fixture equips three adjustment screw rods, the angle of fine setting catoptron.
Described catoptron is a pair high reflectivity mirror, be assemblied in described catoptron fixture respectively, form a stable resonator cavity, high reflection mirror two sides adopts spherical pad and corrugated gasket clamping plated film high reflective mirror respectively, spherical pad adds one deck annular shim again seal for cavity, simultaneously cavity outermost loads one piece of piece of stainless steel with optical window and seals, and adopts M6 stud to lock.
The reflecting surface of described catoptron directly contacts with gaseous sample, together constitutes the good gas sample chamber of a sealing with steel pipe.
Described current-modulation device comprises function signal generator 10, digital delay/pulse signal generator 7, oscillograph 8 and computing machine 9; The triangular wave that described function signal generator 10 exports is input in laser controller 6 by as external modulation signal; Laser controller 6 and laser instrument 1 are by the clamping of semiconductor laser diode stationary fixture, and described laser instrument 1 adopts semiconductor DFB laser diode, are 14 pin butterfly encapsulation; The single-mode optical fiber pigtail being FC/APC by interface type exports.
Photodetector signal intensity monitored by described digital delay/pulse signal generator 7, and send pulse signal, is input in described laser controller after the signal of described pulse signal and described function signal generator synthesizes a road signal by a combiner.
Described diaphragm pressure sensor is arranged on the gas outlet place in steel tubular chamber, and its measurement range is 0.5-1000Torr.
The control flow of CW-CRDS system as shown in Figure 4.Within the system, laser instrument 1 both can export Single wavelength all the time, also its output wavelength constantly can being changed by controlling its working temperature, therefore, can say that this system has Single wavelength and length scanning two kinds of mode of operations.Wherein, length scanning mode control flow is as follows:
The current parameters of setting laser controller 6, digital delay/pulse signal generator activation threshold value and pulse output parameter, the triangular modulation signal parameter of function signal generator 10, and setting laser controller 6 initial temperature parameter.
Laser instrument 1 current controling signal after synthesis and temperature control signals are inputed to laser diode fixture, now laser instrument 1 Output of laser.
Use the output intensity of photodetector 5 real-time detection resonator cavity, and detector 5 signal is divided into two-way, input to digital delay/pulse signal generator 7 and oscillograph 8 respectively.
Digital delay/pulse signal generator 7 carries out Real-Time Monitoring to the signal from detector 5, when its intensity reaches default activation threshold value, digital delay/pulse signal generator 7 will export two-way trigger pip simultaneously, wherein a road is as enable signal for turning off Laser output, and another road signal is used for trigger oscillographic device 8.
Oscillograph after being triggered 8 pairs of cavity-type BPM signals gather, until collect n cavity-type BPM event procedure.
After oscillograph 8 has gathered, will the temperature parameter of laser controller 6 be reset, repeat 2-5 step, until complete temperature scanning.
Wherein, described computing machine 9 is microcomputer general at present or video work station, for carrying out data processing.Photomultiplier detects each and declines and swing waveform and deliver to analog to digital converter, is digitized as 1000 data points and is input to computing machine.Then carry out matching with a simple decaying exponential function to data point, obtain the signal attenuation time, concrete steps are as follows:
First, choose the cavity-type BPM time window signal of certain length, usually choose from the time point that cavity-type BPM signal intensity is the strongest, the width difference of time window also can have influence on fitting result.
Secondly, carry out natural logarithm (ln) computing to the data in this time window, now the funtcional relationship of signal data and horizontal ordinate time shaft becomes linear function from exponential function.
Finally, carry out linear fit to the data that previous step obtains, the inverse of gained fit slope is the cavity-type BPM time.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (7)
1. the portable acetone scentometer of a real time on-line monitoring fat combustion, it is characterized in that: comprise laser instrument and laser controller, optoisolator, gas sample chamber, photo-detector and current-modulation device, described gas sample chamber forms primarily of three parts: steel tubular chamber, catoptron fixture and catoptron.
2. the portable acetone scentometer of a kind of real time on-line monitoring fat combustion according to claim 1, is characterized in that the described long 500mm in steel tubular chamber, internal diameter 35mm, is furnished with three air inlet/outlets; Tubular cavity surface is coated with one deck quartz; Described gas sample chamber two ends respectively have a catoptron fixture to be connected with the port of tubular cavity, and described catoptron fixture equips three adjustment screw rods, the angle of fine setting catoptron; Described catoptron is a pair high reflectivity mirror, be assemblied in described catoptron fixture respectively, form a stable resonator cavity, high reflection mirror two sides adopts spherical pad and corrugated gasket clamping plated film high reflective mirror respectively, spherical pad adds one deck annular shim again seal for cavity, simultaneously cavity outermost loads one piece of piece of stainless steel with optical window and seals, and adopts M6 stud to lock; The reflecting surface of described catoptron directly contacts with gaseous sample, together constitutes the good gas sample chamber of a sealing with steel pipe.
3. the portable acetone scentometer of a kind of real time on-line monitoring fat combustion according to claim 1, is characterized in that described current-modulation device comprises function signal generator, digital delay/pulse signal generator, oscillograph and computing machine; The triangular wave that described function signal generator exports is input in laser controller as external modulation signal; Laser controller and laser instrument are by the clamping of semiconductor laser diode stationary fixture, and described laser instrument adopts semiconductor DFB laser diode, are 14 pin butterfly encapsulation; The single-mode optical fiber pigtail being FC/APC by interface type exports.
4. the portable acetone scentometer of a kind of real time on-line monitoring fat combustion according to claim 3, it is characterized in that described digital delay/pulse signal generator monitoring photodetector signal intensity, and send pulse signal, be input in described laser controller after the signal of described pulse signal and described function signal generator synthesizes a road signal by a combiner.
5. the portable acetone scentometer of a kind of real time on-line monitoring fat combustion according to claim 4, it is characterized in that diaphragm pressure sensor is arranged on the gas outlet place in steel tubular chamber, its measurement range is 0.5-1000Torr.
6. the modulator approach of the portable acetone scentometer of a real time on-line monitoring fat combustion, it is characterized in that the wavelength of the current-modulation device modulated laser of the portable acetone scentometer of a kind of real time on-line monitoring fat combustion adopted as described in any one of claim 3-5, described laser instrument both can export Single wavelength all the time, also its output wavelength constantly can be changed by controlling its working temperature, to realize laser and resonator mode coupling, wherein, length scanning mode control flow is as follows:
Step one, the current parameters of setting laser controller, digital delay/pulse signal generator activation threshold value and pulse output parameter, the triangular modulation signal parameter of function signal generator, and setting laser controller initial temperature parameter;
Step 2, inputs to laser diode fixture, now laser instrument Output of laser by the laser diode current control signal after synthesis and temperature control signals;
Step 3, uses the output intensity of photodetector real-time detection resonator cavity, and detector signal is divided into two-way, input to digital delay/pulse signal generator and oscillograph respectively;
Step 4, digital delay/pulse signal generator carries out Real-Time Monitoring to the signal from detector, when its intensity reaches default activation threshold value, digital delay/pulse signal generator will export two-way trigger pip simultaneously, wherein a road is as enable signal for turning off Laser output, and another road signal is used for trigger oscillographic device;
Step 5, the oscillograph after being triggered gathers cavity-type BPM signal, until collect n cavity-type BPM event procedure;
Step 6, after oscillograph collection completes, will reset the temperature parameter of laser controller, repeat two-five steps, until complete temperature scanning.
7. the modulator approach of the portable acetone scentometer of a kind of real time on-line monitoring fat combustion according to claim 6, is characterized in that described computing machine is microcomputer general at present or video work station, for carrying out data processing; Photomultiplier detects each and declines and swing waveform and deliver to analog to digital converter, is digitized as 1000 data points and is input to computing machine; Then carry out matching with a simple decaying exponential function to data point, obtain the signal attenuation time, concrete steps are as follows:
First, choose the cavity-type BPM time window signal of certain length, usually choose from the time point that cavity-type BPM signal intensity is the strongest, the width difference of time window also can have influence on fitting result;
Secondly, carry out natural logarithm (ln) computing to the data in this time window, now the funtcional relationship of signal data and horizontal ordinate time shaft becomes linear function from exponential function;
Finally, carry out linear fit to the data that previous step obtains, the inverse of gained fit slope is the cavity-type BPM time.
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| US10184890B2 (en) | 2017-03-10 | 2019-01-22 | Sharp Kabushiki Kaisha | Gas analyzer with low optical noise |
| CN109839477A (en) * | 2017-11-24 | 2019-06-04 | 内蒙古光能科技有限公司 | A kind of method that CRDS gas concentration detector accelerates measurement |
| CN114431898A (en) * | 2021-12-23 | 2022-05-06 | 新绎健康科技有限公司 | Ketone body detection device based on respiratory gas |
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