CN105249939A - Physiology detection module capable of denoising and physiology detection method thereof - Google Patents
Physiology detection module capable of denoising and physiology detection method thereof Download PDFInfo
- Publication number
- CN105249939A CN105249939A CN201410340967.4A CN201410340967A CN105249939A CN 105249939 A CN105249939 A CN 105249939A CN 201410340967 A CN201410340967 A CN 201410340967A CN 105249939 A CN105249939 A CN 105249939A
- Authority
- CN
- China
- Prior art keywords
- filtering
- light
- physiological
- signal
- order
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
A physiology detection module comprises a light source module, a sensing area and a control module. The light source module is used for emitting green light, red light and infrared light to irradiate the surface of the skin at time intervals. The sensing area is used for sensing transmitted light emitted from the light source module, irradiating the surface of the skin, and penetrating the body tissue, and correspondingly generating a green light signal, a red light single and an infrared light signal. The control module is used for determining filter parameters according to the green light signal so as to filter the red light signal and the infrared light signal, and calculating physiological features according to at least one of the green light signal, the post-filter red light signal and the post-filter infrared light signal.
Description
Technical field
The present invention about a kind of physiological detection module, particularly about a kind of physiological detection module with noise removal function.
Background technology
Known blood oxygen saturation instrument (pulseoximeter) utilizes the mode of non-intrusion type to detect blood oxygen concentration and the Pulse Rate of user, it can produce red light beam (wavelength about 660 how rice) and infrared light (wavelength about 910 how rice) and penetrate detected part, and utilize band oxygen haemachrome (oxyhemoglobin) and deoxygenated blood red pigment (Deoxyheamo-globin) special spectrum to be had to the characteristic of different absorbance to detect the intensity variation of penetrating light, such as with reference to United States Patent (USP) the 7th, 072, No. 701, title is the monitoring mode (Methodforspectrophotometricbloodoxygenationmonitoring) of blood oxygen concentration.After detecting the intensity variation of the penetrating light of two kinds of wavelength, such as light change in volume (Photoplethysmograph) signal or PPG signal, again with following formulae discovery blood oxygen concentration, blood oxygen concentration=100% × [HbO2]/([HbO2]+[Hb]); Wherein, [HbO2] represents band oxygen hemoglobin concentration; [Hb] represents deoxygenated blood lycopene concentration.
The light intensity of the penetrating light of two kinds of wavelength detected by general blood oxygen saturation instrument can present strong and weak change along with heart beating, this be due to blood vessel can along with heart beating constantly enlargement and contraction and blood flow volume that light beam is passed through changes, and then change light energy absorbed ratio.By this, the intensity information according to constantly change then can calculate the absorbance of blood to different spectrum, to calculate physiologic information such as band oxygen hemoglobin concentration and deoxygenated blood lycopene concentration etc. respectively, finally recycles above-mentioned blood oxygen concentration formulae discovery blood oxygen concentration.
But, because blood oxygen saturation instrument detects the Strength Changes through bodily tissue light, thus different light intensity signals can be detected along with different detected part; In addition, when blood oxygen saturation instrument and the detected part generation relative movement detected, then chaotic waveform can be detected and be difficult to correctly calculate physiological feature, thus under the testing conditions of nonstatic state and be not easy detect correct body of light amass variable signal (PPGsignal).
Summary of the invention
In view of this, the present invention proposes a kind of physiological sensing device being applicable to nonstatic detected state.
The invention provides a kind of physiological sensing module in order to be incorporated into earpiece and at least one physiological feature in skin face after detecting ear.Described physiological detection module comprises joint portion and detecting unit.Described joint portion is in order to be incorporated into described earpiece.Described detecting unit has detection faces in order to skin face after being attached at described ear and comprises light source module, sensing block and control module.Described light source module sends green glow, HONGGUANG and infrared light to irradiate skin face after described ear in order to timesharing.Described sensing block sends irradiate skin face after described ear and through systemic penetrating light with corresponding generation green optical signal, red signal light and infrared signal in order to sense described light source module.Described control module in order to control the luminescence of described light source module and to determine that filtering parameter is to carry out filtering to described red signal light and described infrared signal according to described green optical signal, and calculates described physiological feature according to infrared signal at least one wherein after red signal light after described green optical signal, filtering and filtering.
The present invention also provides a kind of physiological sensing module in order to detect at least one physiological feature in skin face in auricular concha.Described physiological detection module comprises main body, protuberance and detecting unit.Described protuberance from described main body outwardly in order to insert in auricular concha.Described detecting unit is positioned at described protuberance and has detection faces in order to be attached at described auricular concha skin face.Described detecting unit comprises light source module, sensing block and controls module.Described light source module sends green glow, HONGGUANG and infrared light to irradiate skin face in described auricular concha in order to timesharing.Described sensing block sends irradiate skin face in described auricular concha and through systemic penetrating light with corresponding generation green optical signal, red signal light and infrared signal in order to sense described light source module.Described control module is in order to control the luminescence of described light source module and to determine that filtering parameter is to carry out filtering to described red signal light and described infrared signal, calculates described physiological feature according to infrared signal at least one wherein after red signal light after described green optical signal, filtering and filtering according to described green optical signal.
The present invention also provides a kind of physiological feature detection method of physiological sensing module, and described physiological detection module comprises light source module and sensing block, in order at least one physiological feature on detection of skin surface.Described detection method comprises the following step: send skin surface described in green glow, HONGGUANG and Infrared irradiation with during described light source die component; Sense described light source module with described sensing block to send and irradiate described skin surface through systemic penetrating light with corresponding generation green optical signal, red signal light and infrared signal; Filtering parameter is determined according to described green optical signal; With described filtering parameter, filtering is carried out to produce after filtering infrared signal after red signal light and filtering to described red signal light and described infrared signal; And calculate described physiological feature according to infrared signal at least one wherein after red signal light after described green optical signal, described filtering and described filtering.
More obviously, hereafter can will coordinate appended diagram, be described in detail as follows to allow above and other object of the present invention, feature and advantage.In addition, in explanation of the present invention, identical component represents with identical symbol, first states clearly at this.
Accompanying drawing explanation
Figure 1A is the block chart of the physiological detection module of the embodiment of the present invention;
Figure 1B is the running schematic diagram of the physiological detection module of the embodiment of the present invention;
Fig. 2 A and 2B is the frequency domain signal diagrams of the detection signal of the physiological detection module of the embodiment of the present invention;
Fig. 3 A and 3B is the schematic diagram that the physiological detection module of the embodiment of the present invention is applied to glasses;
Fig. 4 is that the physiological detection module of the embodiment of the present invention wears schematic diagram when being applied to glasses;
Fig. 5 is the schematic diagram that the physiological detection module of the embodiment of the present invention is applied to supra-aural accessory;
Fig. 6 is the schematic diagram of the slim physiological detection module of the embodiment of the present invention;
Fig. 7 is the top view of the sensing block of the physiological detection module of the embodiment of the present invention;
Fig. 8 A and 8B is the top view of the physiological detection module of the embodiment of the present invention;
Fig. 9 A and 9B is the sectional view of the thin semiconductor structure of the physiological detection module of the embodiment of the present invention; And
Figure 10 is the flow chart of the physiological detection method of the physiological detection module of the embodiment of the present invention.
Description of reference numerals
1 physiological detection module
10 detecting units
101 light source modules
101a, 101b, 101c light source
102 substrates
102S substrate surface
103 sensor pixels
103A senses block
104 thin semiconductor structures
105 contacts
106 control module
108 represent unit
109 power supply modules
130 joint portions
131 adjustment parts
150 main bodys
151 protuberances
201 wafers
203 flatness layers
205 scratch-resistant layer
201S wafer surface
3 earpieces
S skin surface
Sd detection faces
S
41-S
45step
PPG detection signal
Detailed description of the invention
The invention provides a kind of physiological sensing device being applicable to wear-type accessory, can be incorporated into such as, but not limited to, glasses or Headphone device, and there is the function eliminating the mobile noise caused.Physiological sensing device of the present invention also can utilize fixture to be incorporated into other headwears (headgear), such as by cramp assembling and disassembling in cap body (hat) or helmet body (cap), therefore just can arrange when needs use, to increase practicality.
Please refer to shown in Figure 1A, it is the block schematic diagram of the physiological detection module of the embodiment of the present invention, comprises light source module 101, sensing block 103A, controls module 106, represents unit 108 and power supply module 109.Described light source module 101, sensing block 103A and control module 106 can form detecting unit 10 and by detection faces Sd detection of skin surface S at least one physiological feature, such as pulse, blood oxygen concentration and/or acceleration pulse wave volume (secondderivativeofPhotoplethysmogram); Wherein, be known according to the mode of PPG signal detection pulse, blood oxygen concentration and acceleration pulse wave volume, therefore repeated no more in this.Described expression unit 108 shows described physiological feature by the mode of sound or image, such as, comprise speaker module or display etc.Electric power required when described power supply module 109 is in order to provide described detecting unit 10 to operate.Should be noted that, when physiological detection module 1 is incorporated into wear-type device (after being illustrated in), described expression unit 108 and described power supply module 109 can be shared with wear-type device and use and be not contained in physiological detection module 1, and only need be electrically connected at physiological detection module 1 carries out signal transmission.
Described light source module 101 such as comprises at least one light-emittingdiode, at least one Laser Diodes, at least one organic light emitting diode or other active light sources, sends green glow, HONGGUANG and infrared light to irradiate described skin surface S in order to timesharing.In one embodiment, described light source module 101 comprises single light source, and it drives parameter (such as drive current or driving voltage) to change luminous frequency spectrum, to send green glow, HONGGUANG and infrared light by adjustment; Wherein, green wavelength such as can between 490 Nai meter-570 how rice, HONGGUANG and infrared light then for general in order to detect physiological feature time the wavelength that uses.In another embodiment, described light source module 10 comprises green-light source, red-light source and infrared light light source in order to send green glow, HONGGUANG and infrared light respectively.
Described sensing block 103A is such as quasiconductor sensing block, and it comprises multiple sensor pixel and each sensor pixel comprises at least one near-infrafed photodiodes in order to light energy is converted to the signal of telecommunication.Described sensing block 103A in order to sense described light source module 101 send and irradiate described skin surface S through systemic penetrating light with corresponding generation green optical signal, red signal light and infrared signal; Wherein, described green optical signal, described red signal light and described infrared signal system also can be described as body of light and amass variable signal or PPG signal.
Timesharing is luminous in order to control the light sensing of described light source module 101 relatively described sensing block 103A for described control module 106, as shown in Figure 1B; Wherein, the signal sequence of Figure 1B only in order to illustrate, and is not used to limit the present invention.When physiological sensing device 1 is applicable to wear-type accessory, between detection period, physiological sensing device 1 and skin surface S may can not maintain stable relative position and produce noise in detection signal (i.e. PPG signal).Therefore, the present invention utilizes described green optical signal to determine filtering parameter, and carries out filtering to described red signal light and described infrared signal according to this.
Shown in Fig. 2 A, its detection red signal light that is physiological sensing device 1 or infrared signal are converted to the schematic diagram of the energy frequency spectrum Density Distribution (PSD) of frequency domain, and the dominant frequency in frequency domain detection signal is not obvious because noise exists.Due to SPO
2for green glow, there is higher absorbance, the schematic diagram that green optical signal is converted to the energy frequency spectrum Density Distribution (PSD) of frequency domain is detected if Fig. 2 B is physiological sensing device 1, therefore filtering parameter as described in can determining according to frequency domain green optical signal (as Fig. 2 B), such as now can the signal component of frequency 1Hz as reference frequency; Wherein, described control unit 106 such as can utilize Fourier analysis, wavelet analysis or other algorithms etc. that PPG signal is converted to frequency domain.Described control module 106 also carries out filtering to produce after filtering infrared signal after red signal light and filtering respectively with described filtering parameter to described red signal light and described infrared signal.In one embodiment, the signal component that after described filtering, red signal light is reference frequency described in frequency domain red signal light (such as Fig. 2 A) converts back time domain and is tried to achieve; The signal component that after described filtering, infrared signal is reference frequency described in frequency domain infrared signal (such as Fig. 2 A) converts back time domain and is tried to achieve.
Described control module 106 can calculate described physiological feature according to infrared signal one at least wherein after red signal light after described green optical signal, filtering and filtering.In one embodiment, described pulse and described acceleration pulse wave volume can be tried to achieve according to infrared signal one wherein after red signal light after described green optical signal, described filtering and described filtering; Described blood oxygen concentration is tried to achieve according to infrared signal after red signal light after described filtering and described filtering.
Should be noted that, when physiological sensing device 1 is incorporated into other devices, such as earphone, the partial function of described control module 106 can be performed by the processing unit of described device, such as, in some embodiment, physiological sensing device 1 only detects PPG signal, and the process of PPG signal, filtering and calculating physiological feature can be performed by external processing unit.
Please refer to shown in Fig. 3 A, 3B and 4, Fig. 3 A and 3B is that physiological sensing device 1 is applied to the schematic diagram of glasses and Fig. 4 is physiological sensing device 1 when being applied to glasses wears schematic diagram.Now, physiological detection module 1 is in order to be incorporated into earpiece 3 and at least one physiological feature of skin face S (as shown in Figure 4) after detecting the ear of relative temporal bone (temporalbone).In some embodiment, physiological sensing device 1 comprises joint portion 130 and detecting unit 10; Wherein, described detecting unit 10 comprises light source module 101, sensing block 103A and controls module 106 as previously mentioned, and has detection faces Sd in order to be attached at skin face S after described ear; Also namely, aforementioned skin surface S now refers to skin face after ear.Described joint portion 130 is in order to be incorporated into described earpiece 3.In some embodiment, physiological sensing device 1 is fixedly arranged on described earpiece 3 by described joint portion 130.In other embodiments, physiological sensing device 1 is removably installed in described earpiece 3 by described joint portion 130.
In addition, the position conveniently adjusting physiological detection module 1 is to enable its detection faces Sd correctly to being positioned at skin face S after ear, and physiological detection module 1 can comprise adjustment part 131 (as shown in Figure 3 B) and be connected between described joint portion 130 and described detecting unit 10 in order to adjust the position of described detecting unit 10; Wherein, described adjustment part 131, made by soft materials, produces deformation when exposed to external forces and maintains state at that time when not being subject to external force.In addition, physiological detection module 1 can be formed as single branch (branch) as shown in Figure 3A or be formed as multiple branch as shown in Figure 3 B; Wherein, different branch can in order to arrange different elements.Such as, in Fig. 3 A, power supply module and detecting unit are arranged in same branch and Fig. 3 B power supply module 109 and detecting unit 10 are positioned at different branch.
In addition, when physiological detection module 1 is incorporated into the glasses with Presentation Function, such as, when comprising LCOS display, described glasses can form the glasses module that can detect physiological feature in order to show the physiological feature of physiological detection module 1 detection.
Please refer to shown in Fig. 5, in another embodiment, physiological detection module 1 can in order to detect at least one physiological feature of skin face S in auricular concha.Now, physiological detection module 1 comprises main body 150 and protuberance 151 from described main body 150 outwardly in order to insert in auricular concha.Detecting unit is then positioned at described protuberance 151 and has detection faces Sd in order to be attached at described auricular concha skin face S; Also namely, now aforementioned skin surface S is skin face in auricular concha.In addition, represent that unit 108 and power supply module 109 can be arranged at described main body 150.Such as, described expression unit 108 can be display or speaker module, represents by the mode of display or sound the physiological feature that physiological detection module 1 detects.In addition, in this enforcement, detecting unit comprises light source module 101, sensing block 103A equally and controls module 106, before its function and running have been described in, therefore repeats no more in this.
In one embodiment, physiological detection module 1 can be incorporated into Headphone device, such as wireless bluetooth earphone.Should be noted that, although physiological detection module 1 is shown as earphone pattern in Fig. 4, but when physiological detection module 1 when not being incorporated into earphone for independent component, also can being formed as other shapes, being not limited to the shape that Fig. 5 discloses.In addition, for ease of fixing, physiological detection module 1 also can comprise other structures in order to be sheathed on above external ear or head, there is no specific restriction.
Fig. 6 is the detecting unit of the slim physiological detection module of one embodiment of the invention, comprises at least one light source 101, substrate 102, multiple sensor pixel 103 and multiple contact 105; Wherein, described sensor pixel 103 forms semiconductor optical sensing block 103A, and it has thin semiconductor structure 104 (illustrating in Fig. 9 A and 9B further).Described contact 105 senses block 103A electrically connect to described substrate 102 in order to make semiconductor optical, controls module 106 (as shown in Figure 1A) to be controlled by; Wherein, described sensor pixel 103 can be positioned at wafer 201 and described contact 105 can as described wafer 201 to the electrical contact of outside.Described light source 101 is electrically connect extremely described substrate 102 also, and described control module 106 irradiates skin surface S for controlling the luminescence of described light source 101, the light of transmitting is made to enter bodily tissue positions such as (after such as aforesaid ear in skin face and auricular concha) skin faces of user.Described control module 106 also controls described sensor pixel 103 and senses the light transmitted from bodily tissue simultaneously.Because the blood vessel in bodily tissue, blood etc. all have different optical properties, therefore by the specific light source 101 of arrangement, the optical image just sensed by described sensor pixel 103 is to carry out physiological feature judgement.
In more detail, described control module 106 can be integrated in described wafer 201 or be arranged on described substrate 102 (can be positioned at the identical or different surface of described substrate 102 with described wafer 201), in order to control described light source 101 and described semiconductor optical sensing block 103A.Described substrate 102 has substrate surface 102S, and described wafer 201 and described light source 101 are in order to be arranged on described substrate surface 102S.In the present embodiment, in order to effectively reduce overall volume, described wafer 201 is less than 8 millimeters with the relative distance of described light source 101 is better.
In some embodiment, contact 105 can be conducting wire frame structure, and in other embodiments, contact 105 also can be the forms such as projection, ball array, wire, but is not used to limit the present invention.
In some embodiment, sensing block 103A area can more than 25mm
2quasiconductor sensing block can obtain image continuously with speed more than hundreds of frame (hundredsofframes) per second, and such as described control module 106 controls described semiconductor optical sensing block and obtains optical image with speed more than 300 frames per second and control described light source 101 and coordinate image capturing luminous.
Fig. 7 describe semiconductor optical of the present invention sensing block 103A on look signal, at detection physiological feature, such as during the application such as blood oxygen concentration, heart beating (pulse), blood pressure, move owing to can not produce Rapid Relative between skin surface S and detection faces Sd, the width therefore sensing block 103A seriously can't have influence on sensing result.Fig. 7 display be the sensing block 103A of zone of approach block-type, the ratio of its transverse width and longitudinal width can between 0.5-2.Thus, no matter user is when will detect the physiological features such as veinprint, blood oxygen concentration, heart beating, blood pressure or acceleration pulse wave volume, all only sensing block 103A must be fitted in skin surface S.The sensing area of this sensing block 103A at least should be greater than 25mm
2.
Fig. 8 A, 8B describe the upper schematic diagram that slim physiological feature of the present invention detects module, and it is mainly used to the configuration of light source and the application of multiple light source are described.In Fig. 8 A, illustrate side light source 101 being positioned over multiple sensor pixel 103, and with substrate 102 electrically connect.The present embodiment Notable be, although light source 101 is positioned over the side of sensor pixel 103, but in the middle of light penetration to the bodily tissue of user, therefore the position that light source is placed does not affect the direction of detecting unit, only need in detection process, skin surface continues to be subject to light source irradiation.
In the fig. 8b, three kinds of different light source 101a, 101b and 101c are illustrated.In the present embodiment, different light sources means the light source that can send different wave length light.Because the composition in tissue is for the light of different wave length, there is different reactions, such as there is different absorbances, therefore by the sensing to Different Light, just can derive and learn the physiological feature relevant to optical wavelength, also by the sensing image to Different Light, mutual correction can be done, to obtain sensing result more accurately.Such as, oxygen composition in blood is not identical for the absorbance of different color light, therefore by the energy of sensing different color light, just can derive and learn blood oxygen concentration.In other words, the slim physiological feature of the present embodiment detects module and can comprise the light that three kinds of light sources 101a, 101b and 101c send different wave length respectively, such as HONGGUANG, infrared light and green glow, semiconductor optical sensing block comprises three kinds of sensor pixels respectively in order to sense the light of the different wave length that described light source sends.
For example, if will blood oxygen concentration detection be carried out, then can use HbO
2and the light of latter two wavelength before Hb isobestic point wavelength 805nm, such as can select to be respectively wavelength about 660nm, and the light of wavelength about 940nm; Or can 730-810nm be selected, or the light of 735-895nm.By the difference of blood for the trap of two kinds of wavelength light, blood oxygen concentration can be derived.Green wavelength then can mat in green glow spectral range.Relevant measuring technique, known by this art person known, does not repeat them here
By the understanding to Fig. 8 A, 8B, can learn that the present invention can apply multiple light source, be not limited to single light source or two light sources, and can in response to for measure physiological feature arrange different sensor pixels, carry out corresponding more the more individual light source, and the position of light source might not.Under slim framework, the present invention can be applicable to many physiological features sensing.Different light sources can be placed to detect physiological feature in the lump.If in order to obtain more uniform image, same light source can be arranged in the both sides of same sensing block, making light can enter the bodily tissue of user from the both sides of sensing block simultaneously.
Fig. 9 A, 9B illustrate the generalized section of semiconductor optical of the present invention sensing block, and it is the partial schematic diagram of thin semiconductor structure 104.Fig. 9 A illustrates the embodiment that flatness layer 203 has anti-scratch ability simultaneously, such as, using pi (Polyimide) as the material of flatness layer 203, just has enough anti-scratch abilities and can be applied in the middle of the present invention; Also namely, now namely described flatness layer 203 is used as scratch-resistant layer.Flatness layer 203 be formed at chip architecture 201 the top and be positioned on wafer surface 201S, and be covered in semiconductor optical sensing block on to protect semiconductor structure 104.Because chip architecture 201 may because semiconductor layout in its top when being formed, after formation metal level and electrode, many concavo-convex places (as shown in the figure) can be had, be unfavorable for that optics senses, simultaneously also less weather-proof ability, therefore form flatness layer 203 in the top, make thin semiconductor structure 104 have smooth surface, be more conducive to being applied in the middle of the present invention.In the present invention, thin semiconductor structure 104 will be exposed in the middle of air continually, and with the Body contact of user, therefore need to possess preferably anti-scratch ability; In contemporary semiconductor process technique, can be that benchmark is to screen anti-scratch material with pi.Simultaneously flatness layer 203 needs to possess the character that visible ray or black light can pass, and light source of can arranging in pairs or groups is selected.In addition, anti-scratch material may also be glass or similar material, and scratch-resistant layer can be glassy layer.
It should be noted that, make image generation fuzzy in order to lower light through the spreading effect that may produce during flatness layer 203, preferably the surface of semiconductor structure 104 is to the distance on the surface of chip architecture 201, be exactly the height of flatness layer 203 in the present embodiment, need to be limited in 100 microns (μm) below.Also namely, wafer surface 201S is less than 100 microns to the distance of upper surface of described flatness layer 203 (i.e. scratch-resistant layer) is better.When detecting physiological feature, namely the upper surface of described flatness layer 203 is also sensed by semiconductor optical sensing block via after described flatness layer 203 through described bodily tissue with for directly contacting described skin surface S, skin surface S described in the light direct irradiation sent to make described light source 101 as detection faces Sd.In one embodiment, the light-emitting area of described light source 101 and the distance of described substrate surface 102S can be same as the upper surface of described flatness layer 203 and the distance of described substrate surface 102S.Also, namely, when the light-emitting area of described light source 101 has phase co-altitude with the upper surface of described flatness layer 203, the light that described light source 101 sends can sense to be sensed block by semiconductor optical to enter described body part through skin surface efficiently.
Fig. 9 B and Fig. 9 A different be in, the flatness layer 203 of Fig. 9 B does not have enough anti-scratch abilities, therefore other cambium layer scratch-resistant layer 205 above flatness layer 203.Similarly, in order to lower light through flatness layer 203 and the spreading effect that may produce during scratch-resistant layer 205, flatness layer 203 needs to be limited in less than 100 microns with the total height of scratch-resistant layer 205 in the present embodiment.In the present embodiment, flatness layer 203 need not consider anti-scratch ability, and scratch-resistant layer 205 can be that benchmark is to screen anti-scratch material with pi.In addition, anti-scratch material may also be glass or similar material, and scratch-resistant layer can be glassy layer.
In some embodiment, also multiple sensing block can be arranged, such as arrange multiple line style sensing block in preset direction successively, or between multiple sensing block, arrange the layout type such as light source, such as multiple linear semiconductor optics sensing block is disposed adjacent or arranges separately with multiple light source, in order to obtain better optical imaging results further, because its sensing principle is identical, therefore illustrate graphic no longer separately.
The purposes of aforesaid base plate 102 is electrically connect light source 101 and sensor pixel 103, and light can be squeezed in tissue by light source play a role, therefore can be the flexual soft substrate plate of tool, or partially hard hard substrate.
In the embodiment of slimming, the skin surface that semiconductor optical sensing block directly can attach user uses, other optical facilities need not carry out image-zooming, conducting light etc. effect, its slim and durable feature can make the present invention be applied on wear-type or supra-aural accessory, the such as wear-type such as glasses, earphone accessory.
In some embodiment, coordinate the light source used, in the manufacture process of sensor pixel, can add different optical filters, sensed pixel absorbed by wave filter to enable desired light.Wave filter can coordinate with manufacture of semiconductor, utilizes existing technology to be formed on sensor pixel, also can after sensor pixel completes, formed thereon in addition.Be mixed into filtering material by protective layer and/or flatness layer, protective layer and/or flatness layer also can be made to have filter effect.Also namely, different sensor pixel described in the embodiment of the present invention can be the sensor pixel coordinating different light filter, but not different between sensor pixel itself.
Scrutable, be reduced volume, physiological detection module 1 is that embodiment illustrates with Fig. 6, and right the present invention is not limited to this.In some embodiment, between light source 101 and skin surface S to be measured, also can have other optical facilities, between sensing block 103A and skin surface S to be measured, also can have other optical facilities, look closely its application and determine.
Please refer to shown in Figure 10, it is the flow chart of the physiological feature detection method of the physiological detection module of the embodiment of the present invention, comprises the following step: to send green glow, HONGGUANG and Infrared irradiation skin surface (step S during light source die component
41); With the quasiconductor sensing block sensing described skin surface of irradiation and through systemic penetrating light with corresponding generation green optical signal, red signal light and infrared signal (step S
42); Filtering parameter (step S is determined according to described green optical signal
43); With described filtering parameter, filtering is carried out to produce after filtering infrared signal (step S after red signal light and filtering to described red signal light and described infrared signal
44); And calculate at least one physiological feature (step S according to infrared signal one at least wherein after red signal light after described green optical signal, described filtering and described filtering
45).
Shown in Figure 1A-2B, 6 and 10, the embodiment of the present embodiment is then described.
Step S
41-S
42: described control module 106 sends green glow, HONGGUANG and Infrared irradiation skin surface S with controlling the timesharing of described light source module 101, and the corresponding control of the luminescence described sensing block 103A of relatively described light source module 101 sense described light source module 101 send and irradiate described skin surface S through systemic penetrating light (as Figure 1B) with corresponding generation green optical signal, red signal light and infrared signal; Wherein, described green optical signal, red signal light and infrared signal are PPG signal.Described skin surface S then determines according to the application of described light source module 101.
Step S
43: described control module 106 utilizes built-in algorithm described green optical signal is converted to frequency domain and produces frequency domain green optical signal (as Fig. 2 B), and determine that reference frequency is as filtering parameter in described frequency domain green optical signal, the such as frequency content of the 1Hz shown in Fig. 2 B.
Step S
44: described red signal light and infrared signal are converted to described frequency domain to produce frequency domain red signal light and frequency domain infrared signal by described control module 106 equally, as shown in Figure 2 A, now may be not easy to tell dominant frequency signal component because noise is too many.Described control module 106 is according to step S
43the filtering parameter determined, converts back time domain by the signal component of relevant with frequency domain infrared signal for described frequency domain red signal light described reference frequency (such as 1Hz), to produce after filtering infrared signal after red signal light and filtering; Wherein, after described filtering, after red signal light and described filtering, infrared signal is filtered PPG signal.
Step S
45: last, due to the most of filtering of the mobile noise in infrared signal after red signal light after filtering and described filtering, therefore described control module 106 can calculate physiological feature according to this, wherein utilize HONGGUANG PPG signal and infrared light PPG signal to calculate the mode of blood oxygen concentration for known, therefore repeat no more in this.In addition, acceleration pulse wave volume and pulsation can according to single PPG signal calculating and due to SPO
2have higher absorbance to green glow, therefore described control module 106 can try to achieve acceleration pulse wave volume and pulsation according to infrared signal one wherein after red signal light after described green optical signal, described filtering and described filtering.
In sum, known physiological detection module can produce larger noise during skin to be measured in detection is mobile, and not easily correctly detects physiological feature.Therefore, the present invention also proposes a kind of physiological detection module (Figure 1A, 6) and physiological feature detection method (Figure 10) thereof, it decides filtering parameter with the noise in filtering red signal light and infrared signal by green optical signal, uses to improve and detects degree of accuracy.In addition, coordinate the slim feature of physiological detection module, physiological detection module of the present invention can be applicable to various wear-type accessory.
Although the present invention is disclosed by previous examples, it is also not used to limit the present invention, and any technical staff in the technical field of the invention with usual knowledge, without departing from the spirit and scope of the present invention, when doing various changes and amendment.Therefore the scope that protection scope of the present invention ought define depending on accompanying claim is as the criterion.
Claims (20)
1. a physiological detection module, in order to be incorporated into earpiece and at least one physiological feature in skin face after detecting ear, described physiological detection module comprises:
Joint portion, in order to be incorporated into described earpiece; And
Detecting unit, have to be attached at the detection faces in skin face after described ear, described detecting unit comprises:
Light source module, sends green glow, HONGGUANG and infrared light to irradiate skin face after described ear in order to timesharing;
Sensing block, sends skin face through systemic penetrating light with corresponding generation green optical signal, red signal light and infrared signal after the described ear of irradiation in order to sense described light source module; And
Control module, in order to control the luminescence of described light source module and to determine that filtering parameter is to carry out filtering to described red signal light and described infrared signal according to described green optical signal, and calculate described physiological feature according at least one in infrared signal after red signal light after described green optical signal, filtering and filtering.
2. physiological detection module according to claim 1, this detection module also comprises the adjustment part be connected between described joint portion and described detecting unit, in order to adjust the position of described detecting unit.
3. physiological detection module according to claim 1, wherein said physiological feature comprises pulse, blood oxygen concentration and acceleration pulse wave volume.
4. physiological detection module according to claim 3, wherein said pulse and described acceleration pulse wave volume are tried to achieve according to infrared signal one wherein after red signal light after described green optical signal, described filtering and described filtering; Described blood oxygen concentration is tried to achieve according to infrared signal after red signal light after described filtering and described filtering.
5. physiological detection module according to claim 1, wherein said control module is in order to be converted to frequency domain using described green optical signal and to determine that reference frequency is as described filtering parameter.
6. physiological detection module according to claim 5, the signal component that after wherein said filtering, red signal light is reference frequency described in frequency domain red signal light converts back time domain and is tried to achieve; The signal component that after described filtering, infrared signal is reference frequency described in frequency domain infrared signal converts back time domain and is tried to achieve.
7. physiological detection module according to claim 1, this detection module also comprises:
Scratch-resistant layer, being covered on described sensing block and having upper surface as described detection faces, the thickness of wherein said scratch-resistant layer is less than 100 microns;
Wherein when detecting described physiological feature, described upper surface is in order to directly to contact skin face after described ear, and skin face after ear described in the light direct irradiation sent to make described light source module is also sensed by described sensing block via after described scratch-resistant layer through described bodily tissue.
8. physiological detection module according to claim 7, wherein said physiological detection module is incorporated into the glasses comprising display function, and described glasses are in order to show described physiological feature.
9. a physiological detection module, in order to detect at least one physiological feature in skin face in auricular concha, described physiological detection module comprises:
Main body;
Protuberance, from described main body outwardly in order to insert in auricular concha; And
Detecting unit, be positioned at described protuberance and have detection faces in order to be attached at described auricular concha skin face, described detecting unit comprises:
Light source module, sends green glow, HONGGUANG and infrared light to irradiate skin face in described auricular concha in order to timesharing;
Sensing block, sends skin face through systemic penetrating light with corresponding generation green optical signal, red signal light and infrared signal in the described auricular concha of irradiation in order to sense described light source module; And
Control module, in order to control the luminescence of described light source module and to determine that filtering parameter is to carry out filtering to described red signal light and described infrared signal according to described green optical signal, and calculate described physiological feature according at least one in infrared signal after red signal light after described green optical signal, filtering and filtering.
10. physiological detection module according to claim 9, wherein said physiological detection module also comprises and is arranged at power supply module in described main body and represents unit,
Described power supply module is in order to provide described detecting unit electric power; And
Described expression unit is in order to represent described physiological feature.
11. physiological detection modules according to claim 9, wherein said physiological feature comprises pulse, blood oxygen concentration and acceleration pulse wave volume.
12. physiological detection modules according to claim 11, wherein said pulse and described acceleration pulse wave volume are tried to achieve according to infrared signal one wherein after red signal light after described green optical signal, described filtering and described filtering; Described blood oxygen concentration is tried to achieve according to infrared signal after red signal light after described filtering and described filtering.
13. physiological detection modules according to claim 9, wherein said control module is in order to be converted to frequency domain using described green optical signal and to determine that reference frequency is as described filtering parameter.
14. physiological detection modules according to claim 13, the signal component that after wherein said filtering, red signal light is reference frequency described in frequency domain red signal light converts back time domain and is tried to achieve; The signal component that after described filtering, infrared signal is reference frequency described in frequency domain infrared signal converts back time domain and is tried to achieve.
15. physiological detection modules according to claim 9, this detection module comprises:
Scratch-resistant layer, being covered on described sensing block and having upper surface as described detection faces, the thickness of wherein said scratch-resistant layer is less than 100 microns;
Wherein, when detecting described physiological feature, described upper surface is in order to directly to contact skin face in described auricular concha, and skin face in auricular concha described in the light direct irradiation sent to make described light source module is also sensed by described sensing block via after described scratch-resistant layer through described bodily tissue.
16. physiological detection modules according to claim 9, wherein said sensing block comprises respectively in order to detect three kinds of sensor pixels of described HONGGUANG, described infrared light and described green glow.
17. physiological detection modules according to claim 9, wherein physiological detection module is incorporated into Headphone device.
The physiological feature detection method of 18. 1 kinds of physiological detection modules, described physiological detection module comprises light source module and sensing block, and in order at least one physiological feature on detection of skin surface, described detection method comprises:
Skin surface described in green glow, HONGGUANG and Infrared irradiation is sent with during described light source die component;
Sense described light source module with described sensing block to send and irradiate described skin surface through systemic penetrating light with corresponding generation green optical signal, red signal light and infrared signal;
Filtering parameter is determined according to described green optical signal;
With described filtering parameter, filtering is carried out to produce after filtering infrared signal after red signal light and filtering to described red signal light and described infrared signal; And
Described physiological feature is calculated according at least one in infrared signal after red signal light after described green optical signal, described filtering and described filtering.
19. physiological feature detection methods according to claim 18, wherein determine that the step of described filtering parameter comprises:
Described green optical signal is converted to frequency domain and determines that reference frequency is as described filtering parameter.
20. physiological feature detection methods according to claim 19, after wherein producing described filtering, after red signal light and described filtering, infrared signal step comprises:
Described red signal light and infrared signal are converted to described frequency domain to produce frequency domain red signal light and frequency domain infrared signal;
The signal component of described reference frequency relevant in described frequency domain red signal light and described frequency domain infrared signal is converted back time domain to produce after described filtering infrared signal after red signal light and described filtering.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410340967.4A CN105249939A (en) | 2014-07-17 | 2014-07-17 | Physiology detection module capable of denoising and physiology detection method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410340967.4A CN105249939A (en) | 2014-07-17 | 2014-07-17 | Physiology detection module capable of denoising and physiology detection method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105249939A true CN105249939A (en) | 2016-01-20 |
Family
ID=55090110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410340967.4A Pending CN105249939A (en) | 2014-07-17 | 2014-07-17 | Physiology detection module capable of denoising and physiology detection method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105249939A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106997105A (en) * | 2016-01-22 | 2017-08-01 | 周常安 | Have glasses combination, Glasses structure and the binding modules of physiological signal acquisition function |
| CN106997107A (en) * | 2016-01-22 | 2017-08-01 | 周常安 | Have Glasses structure, glasses combination and its binding modules of physiological signal acquisition function |
| CN107303173A (en) * | 2016-04-20 | 2017-10-31 | 元盛生医电子股份有限公司 | The detection method and detection means of individual minimal erythema dose |
| CN108471961A (en) * | 2016-06-15 | 2018-08-31 | 深圳迈瑞生物医疗电子股份有限公司 | A kind of computational methods of physiological parameter and corresponding Medical Devices |
| CN108784675A (en) * | 2017-04-27 | 2018-11-13 | 原相科技股份有限公司 | Can eliminate or avoid offset interference and can accurate measurement physiological characteristic electronic device and method |
| CN109497973A (en) * | 2018-12-24 | 2019-03-22 | 兰州理工大学 | The detection system and detection method of pulse and blood oxygenation information under daily unsupervised state |
| WO2020182047A1 (en) * | 2019-03-12 | 2020-09-17 | 华为技术有限公司 | Blood oxygen detection method and device |
| US10959625B2 (en) | 2017-04-18 | 2021-03-30 | Pixart Imaging Inc. | Electronic apparatus and method capable of reducing or avoiding offset interference and accurately measuring physiological characteristics of user |
| CN113613557A (en) * | 2019-09-27 | 2021-11-05 | 苹果公司 | Physiological monitoring system for measuring blood oxygen concentration |
Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4239844A (en) * | 1979-03-05 | 1980-12-16 | Gte Products Corporation | Electrophotoconductive Cd S Se materials with Cu and Cl |
| WO1998022018A1 (en) * | 1996-11-18 | 1998-05-28 | University Of South Florida | Green light pulse oximeter |
| US5971930A (en) * | 1997-10-17 | 1999-10-26 | Siemens Medical Systems, Inc. | Method and apparatus for removing artifact from physiological signals |
| US7020507B2 (en) * | 2002-01-31 | 2006-03-28 | Dolphin Medical, Inc. | Separating motion from cardiac signals using second order derivative of the photo-plethysmogram and fast fourier transforms |
| US20080167564A1 (en) * | 2007-01-10 | 2008-07-10 | Starr Life Sciences Corp. | Techniques for accurately deriving physiologic parameters of a subject from photoplethysmographic measurements |
| EP2070469A1 (en) * | 2007-12-10 | 2009-06-17 | FUJIFILM Corporation | Image processing system, image processing method, and program |
| US20100324384A1 (en) * | 2009-06-17 | 2010-12-23 | Jim Moon | Body-worn pulse oximeter |
| US7909768B1 (en) * | 2004-07-19 | 2011-03-22 | Pacesetter, Inc. | Reducing data acquisition, power and processing for hemodynamic signal sampling |
| TW201306795A (en) * | 2011-08-05 | 2013-02-16 | Univ Feng Chia | Multi-channel physiological signal measurement device for ear and method thereof |
| WO2013030745A1 (en) * | 2011-09-02 | 2013-03-07 | Koninklijke Philips Electronics N.V. | Camera for generating a biometrical signal of a living being |
| WO2013056379A1 (en) * | 2011-10-19 | 2013-04-25 | Biovotion Ag | System for noninvasive optical measurements of physiological properties in tissue |
| US20140107493A1 (en) * | 2012-06-22 | 2014-04-17 | Fitbit, Inc. | Portable Biometric Monitoring Devices and Methods of Operating Same |
-
2014
- 2014-07-17 CN CN201410340967.4A patent/CN105249939A/en active Pending
Patent Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4239844A (en) * | 1979-03-05 | 1980-12-16 | Gte Products Corporation | Electrophotoconductive Cd S Se materials with Cu and Cl |
| WO1998022018A1 (en) * | 1996-11-18 | 1998-05-28 | University Of South Florida | Green light pulse oximeter |
| US5971930A (en) * | 1997-10-17 | 1999-10-26 | Siemens Medical Systems, Inc. | Method and apparatus for removing artifact from physiological signals |
| US7020507B2 (en) * | 2002-01-31 | 2006-03-28 | Dolphin Medical, Inc. | Separating motion from cardiac signals using second order derivative of the photo-plethysmogram and fast fourier transforms |
| US7909768B1 (en) * | 2004-07-19 | 2011-03-22 | Pacesetter, Inc. | Reducing data acquisition, power and processing for hemodynamic signal sampling |
| US20080167564A1 (en) * | 2007-01-10 | 2008-07-10 | Starr Life Sciences Corp. | Techniques for accurately deriving physiologic parameters of a subject from photoplethysmographic measurements |
| EP2070469A1 (en) * | 2007-12-10 | 2009-06-17 | FUJIFILM Corporation | Image processing system, image processing method, and program |
| US20100324384A1 (en) * | 2009-06-17 | 2010-12-23 | Jim Moon | Body-worn pulse oximeter |
| TW201306795A (en) * | 2011-08-05 | 2013-02-16 | Univ Feng Chia | Multi-channel physiological signal measurement device for ear and method thereof |
| WO2013030745A1 (en) * | 2011-09-02 | 2013-03-07 | Koninklijke Philips Electronics N.V. | Camera for generating a biometrical signal of a living being |
| WO2013056379A1 (en) * | 2011-10-19 | 2013-04-25 | Biovotion Ag | System for noninvasive optical measurements of physiological properties in tissue |
| US20140107493A1 (en) * | 2012-06-22 | 2014-04-17 | Fitbit, Inc. | Portable Biometric Monitoring Devices and Methods of Operating Same |
Non-Patent Citations (3)
| Title |
|---|
| E.M. LEE ET AL.: "Glass-type Wireless PPG Measuring System", 《32ND ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE EMBS BUENOS AIRES, ARGENTINA》 * |
| STEFAN VOGEL ET AL.: "In-Ear Vital Signs Monitoring Using a Novel Microoptic Reflective Sensor", 《IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE》 * |
| Y. MAEDA ET AL.: "Comparison of Reflected Green Light and Infrared Photoplethysmography", 《30TH ANNUAL INTERNATIONAL IEEE EMBS CONFERENCE VANCOUVER, BRITISH COLUMBIA, CANADA》 * |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106997105A (en) * | 2016-01-22 | 2017-08-01 | 周常安 | Have glasses combination, Glasses structure and the binding modules of physiological signal acquisition function |
| CN106997107A (en) * | 2016-01-22 | 2017-08-01 | 周常安 | Have Glasses structure, glasses combination and its binding modules of physiological signal acquisition function |
| CN107303173A (en) * | 2016-04-20 | 2017-10-31 | 元盛生医电子股份有限公司 | The detection method and detection means of individual minimal erythema dose |
| CN107303173B (en) * | 2016-04-20 | 2020-03-17 | 元盛生医电子股份有限公司 | Method and device for detecting minimum erythema dose of individual |
| CN108471961A (en) * | 2016-06-15 | 2018-08-31 | 深圳迈瑞生物医疗电子股份有限公司 | A kind of computational methods of physiological parameter and corresponding Medical Devices |
| US10959625B2 (en) | 2017-04-18 | 2021-03-30 | Pixart Imaging Inc. | Electronic apparatus and method capable of reducing or avoiding offset interference and accurately measuring physiological characteristics of user |
| CN108784675A (en) * | 2017-04-27 | 2018-11-13 | 原相科技股份有限公司 | Can eliminate or avoid offset interference and can accurate measurement physiological characteristic electronic device and method |
| CN109497973A (en) * | 2018-12-24 | 2019-03-22 | 兰州理工大学 | The detection system and detection method of pulse and blood oxygenation information under daily unsupervised state |
| WO2020182047A1 (en) * | 2019-03-12 | 2020-09-17 | 华为技术有限公司 | Blood oxygen detection method and device |
| CN113613557A (en) * | 2019-09-27 | 2021-11-05 | 苹果公司 | Physiological monitoring system for measuring blood oxygen concentration |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10631789B2 (en) | Biometric detection module and biometric detection device with denoising function | |
| CN105249939A (en) | Physiology detection module capable of denoising and physiology detection method thereof | |
| US11633117B2 (en) | Multi-channel photoplethysmography sensor | |
| EP3157412B1 (en) | Physiological monitoring devices and methods using optical sensors | |
| Khan et al. | Organic multi-channel optoelectronic sensors for wearable health monitoring | |
| TW201602826A (en) | Individualized control system utilizing biometric characteristic and operating method thereof | |
| US10302944B2 (en) | Head-mount type display device and method of controlling head-mount type display device | |
| US7376451B2 (en) | Measurement and treatment system and method | |
| WO2017027551A1 (en) | Methods and apparatus for detecting motion via optomechanics | |
| US20040267104A1 (en) | Hat-based oximeter sensor | |
| US20150057511A1 (en) | Sensor and method for continuous health monitoring | |
| US9669235B2 (en) | Phototherapy system that adapts to the position of an infant in neonatal care | |
| US20170076521A1 (en) | Individualized control system utilizing biometric characteristic | |
| US10089802B2 (en) | Individualized control system utilizing biometric characteristic | |
| JP7023403B2 (en) | Measuring device and measuring method | |
| JP2015177403A (en) | Head-mounted display device and method of controlling head-mounted display device | |
| CN105286876A (en) | Personalized control system using physiological characteristics and operating method of personalized control system | |
| US9984222B2 (en) | Individualized control system utilizing biometric characteristic | |
| CN210408435U (en) | Near-infrared brain oxygen detection system | |
| US10403060B2 (en) | Individualized control system utilizing biometric characteristic | |
| CN109998559A (en) | A kind of Near-infrared Brain oxygen detection system and method | |
| US20220117557A1 (en) | Wearable optoelectronic sensing device and manufacturing method thereof | |
| TWM577712U (en) | Earplug device for evaluating sleep quality and improving sleep quality | |
| TW202021530A (en) | Method of using earplug type device to evaluate sleep quality and improve sleep quality and earplug type device thereof that uses sound to stimulate brain to adjust autonomic nervous system and uses color light to stimulate brain cell that is sensitive to light for adjusting the activity of the brain cell | |
| US20230380739A1 (en) | In-ear functional near-infrared spectroscopy for cognitive load estimation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160120 |