CN104940512A - Traditional Chinese medicine composition with enhanced immunity and production technology of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition with enhanced immunity and production technology of traditional Chinese medicine composition Download PDFInfo
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- CN104940512A CN104940512A CN201410112436.XA CN201410112436A CN104940512A CN 104940512 A CN104940512 A CN 104940512A CN 201410112436 A CN201410112436 A CN 201410112436A CN 104940512 A CN104940512 A CN 104940512A
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Abstract
The invention belongs to the technical field of manufacturing of traditional Chinese medicine heath products, and discloses a traditional Chinese medicine composition with enhanced immunity and a production technology of the traditional Chinese medicine composition. Purple yam is named purple ginseng, is high in edible and medicinal value, has nourishing effects of nourishing the lung, benefiting the kidneys and tonifying the spleen, and is capable of improving the immunity of a human body. The purple yam is cultivated in a plurality of provincial areas in the south of the Yangtze River in China; and American ginseng and astragalus membranaceus are important qi-tonifying medicinal materials. A modern research proves that the American ginseng and the astragalus membranaceus are combined to reach the efficacies of tonifying qi, tonifying the spleen, nourishing yin, clearing away heat, and promoting the production of body fluid to relieve thirst; the purple yam can be fully utilized and can be combined with two qi-tonifying medicinal materials such as the American ginseng and the astragalus membranaceus to synergistically play a nourishing role of the purple yam, are capable of enhancing the immunity, can be prepared into the forms such as tablets, granules and capsules, can also be further purified to be prepared into tablets and capsules or granules, and can also be prepared into the forms such as an oral liquid; and the traditional Chinese medicine composition is convenient to carry and use and easy to popularize, and has good economic value.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and the production technology thereof with enhancing immunity, belong to the manufacturing technology field of Chinese medicine health care product.
Background technology
Hypoimmunity is the key character of sub-health population performance, and sub-health population became the crowd such as ascendant trend year by year, particularly intellectual, leading cadre, white collar class in the last few years, and sub-health population number is more than 60%; The bad life style of people and usual aging etc. can cause body's immunity to decline.Therefore immune system needs be maintained and strengthen, and this is 21st century New Conception, and therefore finding the product with good enhancing immunization has become one of developing direction of development in the present age.
Modern medicine is thought, immunity is the defense mechanism of human body self.When many reasons causes immune system normally can not play its defense reaction, then very easily cause the infection such as antibacterial, virus, fungus, thus hypoimmunity the most directly to show be exactly liable to illness.
Traditional medicine thinks that hypoimmunity all belongs to Chinese medicine deficiency-syndrome category, the present invention adopts Rhizoma Dioscoreae, Radix Panacis Quinquefolii, the Radix Astragali, make oral administration solid or liquid dosage form, all medicine synergism, play the merit of invigorating primordial QI, liver and kidney tonifying, invigorating the spleen to benefit the lung, nourshing Yin and drynsessmoistening prescription, promoting the production of body fluid and inducing sedation of the mind altogether, thus effective enhancing human body immunity power, alleviate organism fatigue.Detect tested by Henan Province's Chinese medicine study, safely, have no side effect, obviously strengthen the effect of mice muscle power and resisting fatigue, anoxia endurance and raising immunity.
Rhizoma Dioscoreae (purple D.alata L), gains the name because of overall purple, has another name called purple Radix Ginseng, yampi, Rhizoma Dioscoreae Alatae, have another name called in the localities and have sole potato etc.Rhizoma Dioscoreae belongs to Dioscoreaceae yam, belongs to together not of the same race, belong to the purplish red meat population of Rhizoma Dioscoreae with RHIIZOMA DIOSCOREAE fr0m Henan of China is equal, with the tuber of its hypertrophy or cylindric edible.
Rhizoma Dioscoreae is edible and medical value is all very high, the effect of tool strengthening by means of tonics, and economizing in the Zhejiang of south China, Jiangxi, Yunnan etc. all has extensive cultivation.At present, the successful introduction in Henan Province, is welcome widely.Purple Radix Ginseng is the delicacies on dining table, is again health-care medicinal, is rare senior tonic product, can strengthens body immunity, reduce blood pressure, blood glucose, anti-ageingly to lengthen one's life, have the good reputation of " king of vegetable ".
Rhizoma Dioscoreae is except the carbohydrate containing needed by human body, protein, mineral, vitamin C, aminoacid, trace element, also containing 20 multiple nutrients and health-care components such as anthocyanidin, allantoin, lymphatic temperament, amylase, there is the function of spleen invigorating, nourishing the stomach, tonifying the lung, essence of reinforcing the kidney, support, often eat and can strengthen body immunity, life lengthening.
Rhizoma Dioscoreae contains the unexistent composition of Chinese yam, as anthocyanidin etc.Anthocyanidin has the effect of antioxidation, antiinflammatory, anti-angiogenic sclerosis.Be rich in Rhizoma Dioscoreae soap (natural DHEA), interior containing various hormone base substance, normal food Rhizoma Dioscoreae has the hormonal anabolic effect of promotion endocrine.Containing a large amount of clayey albumen, the lipidosis of cardiovascular system can be prevented, keep arterial vascular elasticity, stop atherosclerosis to occur too early.
The physiological functions such as allantoin has Promote cell's growth, accelerating wound, soften cuticle protein are the good consolidants of skin trauma; Also can be used to alleviate and treatment xeroderma, treat scaling dermatopathy, skin ulcer, digestive tract ulcer and inflammation.Add the cosmetics of allantoin, have skin moistening, protective tissue, hydrophilic, absorb water and the effect such as prevent that moisture from distributing.It can make albumen cutin softening, prevent hair from dividing and, fracture, make hair soft and high resilience, gloss.
Rhizoma Dioscoreae property of medicine tepor, has the effect of good enhancing immunity, and the suitable Chinese medicine as enhancing immunity develops further.
The present inventor is according to the record of the professional data of related pharmaceutical such as China's history tree works, Chinese Pharmacopoeia, Rhizoma Dioscoreae and RHIIZOMA DIOSCOREAE fr0m Henan of China have approximate effect, there is effect of spleen reinforcing nourishing the stomach, invigorating the lung and the kidney, be with inferior disease all effective in cure to cough and asthma due to lung deficiency, insufficiency of the spleen chronic diarrhea, chronic enterogastritis, diabetes, seminal emission.
Up to now, the documents and materials and the patent report that relate to and carry out formula to prepare to have enhancing immunity compositions with Rhizoma Dioscoreae as primary raw material is had no.Therefore, inventor utilizes Rhizoma Dioscoreae, using Rhizoma Dioscoreae as main composition material, adds Radix Panacis Quinquefolii and Radix Astragali raw material of Chinese medicine, develop a kind of can the Chinese medicine composition of enhancing immunity, definite effect, has good market prospect.
Summary of the invention
For the problems referred to above, the object of this invention is to provide a kind of Chinese medicine composition and the production technology thereof with enhancing immunity.
For achieving the above object, the present invention takes following technical scheme:
Said composition is made up of the raw material of following portions by weight proportioning: Rhizoma Dioscoreae 25 ~ 50 parts, the Radix Astragali 25 ~ 50 parts, Radix Panacis Quinquefolii 2 ~ 5 parts.
Object of the present invention is achieved through the following technical solutions:
Must contain Rhizoma Dioscoreae raw material in formula, prescription contains the Radix Astragali, Radix Panacis Quinquefolii in addition, has the effect of enhancing immunity, treatment subhealth state.
The technique of producing Chinese medicine composition is: Rhizoma Dioscoreae, Radix Panacis Quinquefolii, the Radix Astragali are carried out respectively pulverizing or extract concentrated processed, then prepare burden with surplus stock, mix homogeneously, to obtain final product.
It is characterized in that production process is:
(1) clean: by Rhizoma Dioscoreae, Radix Panacis Quinquefolii, the Radix Astragali three taste medical material, removing impurity, rapid water cleans up, dry or cold drying.
(2) pulverize: 1/2 amount Rhizoma Dioscoreae in prescription is ground into 100 order fine powders, for subsequent use.
(3) extract: 1/2 amount Rhizoma Dioscoreae in prescription is extracted twice with Radix Astragali mixing decocting in water by (1), and amount of water is respectively 8 ~ 10 times, 6 ~ 8 times of medical material amount, and extraction time is 45 ~ 60 minutes, 30 ~ 45 minutes, filter, obtain extracting solution.Extracting solution is condensed into the thick paste that relative density is 1.20 ~ 1.30, for subsequent use.(2) by 60% ethanol percolation of 8 ~ 10 times of Radix Panacis Quinquefolii by medical material amount, reclaim ethanol, be condensed into thick paste, for subsequent use.
(4) granulation, drying: the thick paste extracted with Radix Astragali mixing thick paste, Radix Panacis Quinquefolii by the Rhizoma Dioscoreae of the Rhizoma Dioscoreae powder pulverized, water extraction, adds appropriate adjuvant, make granule, 60 DEG C ~ 70 DEG C dryings.
(5) tabletting: tabletting after appropriate magnesium stearate will be added in dried particles.
(6) pack: the tablet pressed is loaded plastic drug package, sealing.Finished product is obtained after adding outer package.Finished product, through after the assay was approved, is preserved in the dry storehouse in cool place.
The present invention compared with prior art, has following advantage and beneficial effect: compared with other strengthens immunoassay product, and the present invention take Rhizoma Dioscoreae as primary raw material, and raw material resources are sufficient, and market prospect is very good, and economic benefit is wide.
1. take full advantage of natural resources of Chinese medicinal materials, expanded the comprehensive utilization of Rhizoma Dioscoreae, the demand that market is different can be met.
2. under Chinese medicine theoretical knowledge instructs, use for reference the achievement of modernization of cmm, selection Rhizoma Dioscoreae is main component, Compatibility with Radix Astragali, Radix Panacis Quinquefolii two taste qi-invigorating herb, be developed to tablet, granule, hard capsule or Oral liquid forms, there is certain scientific and reasonability.
Rhizoma Dioscoreae: also known as purple Rhizomadioscoreae.Warm in nature, sweet in the mouth, has and grows lung kidney tonifying, effect of invigorating the spleen to arrest diarrhea.Be used for the treatment of insufficiency of the spleen diarrhoea, chronic dysentery do not heal, chronic consumptive disease cough, emission due to deficiency of the kidney etc.
The Radix Astragali: slightly warm in nature, sweet in the mouth.There is the title of " length of tonic ".There is effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating, raw by consolidating superficial resistance holder skin ulcer.
Radix Panacis Quinquefolii: cool in nature, sweet in the mouth, micro-hardship.There is boosting qi and nourishing yin, effect of clearing away heat and promoting production of body fluid.Lose for deficiency of vital energy the moon, interior-heat, cough with asthma expectorant blood, deficiency-heat is tired of tired, quenches one's thirst, and dry mouth larynx is done.
3. the crude drug that Chinese medicine composition of the present invention is used is warm in nature coolly to be taken into account, and outstandingly grows lung kidney tonifying, and effect of invigorating the spleen to arrest diarrhea, can improve the malaise symptoms that hypoimmunity causes, and alleviates the fatigue of work, study, work, meets the demand of different crowd.
Detailed description of the invention
By following embodiment, the present invention is illustrated, but the present invention is not limited to the content that the following example comprises.
Embodiment 1
Medical material forms: Rhizoma Dioscoreae 5kg, Radix Astragali 5kg, Radix Panacis Quinquefolii 0.5kg.Technical process: by three taste medical material washings, drying.Get 2.5kg Rhizoma Dioscoreae and be ground into 100 order fine powders.Remaining 2.5kg Rhizoma Dioscoreae and Radix Astragali mixing decocting in water are extracted twice, amount of water is respectively 8 ~ 10 times, 6 ~ 8 times of medical material amount, and extraction time is 45 ~ 60 minutes, 30 ~ 45 minutes, filters, obtain extracting solution, extracting solution is condensed into the thick paste that relative density is 1.20 ~ 1.30; By 8 ~ 10 times 60% ethanol percolation of Radix Panacis Quinquefolii by medical material amount, reclaim ethanol, be condensed into thick paste.By the thick paste that the Rhizoma Dioscoreae of the Rhizoma Dioscoreae powder pulverized, water extraction extracts with Radix Astragali mixing thick paste, Radix Panacis Quinquefolii, add appropriate adjuvant, make granule, 60 DEG C ~ 70 DEG C dryings.Tabletting is medicinal bottled or aluminum-plastic packaged.Add outer package, inspection, gets product.
Embodiment 2
Medical material forms: Rhizoma Dioscoreae 5kg, Radix Astragali 5kg, Radix Panacis Quinquefolii 0.5kg.Technical process: by three taste medical material washings, drying.Get 2.5kg Rhizoma Dioscoreae and be ground into 100 order fine powders.Remaining 2.5kg Rhizoma Dioscoreae and Radix Astragali mixing decocting in water are extracted twice, amount of water is respectively 8 ~ 10 times, 6 ~ 8 times of medical material amount, extraction time is 45 ~ 60 minutes, 30 ~ 45 minutes, filter, obtain extracting solution, extracting solution is condensed into the thick paste that relative density is 1.20 ~ 1.30: by 8 ~ 10 times of 60% ethanol percolation of Radix Panacis Quinquefolii medical material amount, reclaims ethanol, and the thick paste be condensed into.By the thick paste that the Rhizoma Dioscoreae of the Rhizoma Dioscoreae powder pulverized, water extraction extracts with Radix Astragali mixing thick paste, Radix Panacis Quinquefolii, add appropriate adjuvant, make granule that is sugary or sugar-free, 60 DEG C ~ 70 DEG C dryings.Packaging, inspection, gets product.Every packed amount 3g ~ 15g.
Embodiment 3
Medical material forms: Rhizoma Dioscoreae 5kg, Radix Astragali 5kg, Radix Panacis Quinquefolii 0.5kg.Technical process: by three taste medical material washings, drying.Get 2.5kg Rhizoma Dioscoreae and be ground into 100 order fine powders.Remaining 2.5kg Rhizoma Dioscoreae and Radix Astragali mixing decocting in water are extracted twice, amount of water is respectively 8 ~ 10 times, 6 ~ 8 times of medical material amount, and extraction time is 45 ~ 60 minutes, 30 ~ 45 minutes, filters, obtain extracting solution, extracting solution is condensed into the thick paste that relative density is 1.20 ~ 1.30; By 8 ~ 10 times 60% ethanol percolation of Radix Panacis Quinquefolii by medical material amount, reclaim ethanol, be condensed into thick paste.By the thick paste that the Rhizoma Dioscoreae of the Rhizoma Dioscoreae powder pulverized, water extraction extracts with Radix Astragali mixing thick paste, Radix Panacis Quinquefolii, add appropriate adjuvant, make granule, 60 DEG C ~ 70 DEG C dryings; Or by after thick paste and auxiliary materials and mixing, 60 DEG C ~ 70 DEG C dry, pulverize.Granule or powder are incapsulated, aluminum-plastic packaged.Add outer package, inspection, gets product.
Embodiment 4
Medical material forms: Rhizoma Dioscoreae 5kg, Radix Astragali 5kg, Radix Panacis Quinquefolii 0.5kg.Technical process: by three taste medical material washings, drying.Full dose Rhizoma Dioscoreae and Radix Astragali mixing decocting in water are extracted twice, amount of water is respectively 8 ~ 10 times, 6 ~ 8 times of medical material amount, and extraction time is 45 ~ 60 minutes, 30 ~ 45 minutes, filters, obtain extracting solution, extracting solution is condensed into the thick paste that relative density is 1.20 ~ 1.30; By 8 ~ 10 times 60% ethanol percolation of Radix Panacis Quinquefolii by medical material amount, reclaim ethanol, be condensed into thick paste.Two kinds of thick pastes are added in Agitation Tank, add purified water to 10L, with medicinal glass bottle or plastic bottle aseptic subpackaged.Often propping up loading amount is 10ml or 20ml.Add outer package, inspection, gets product.
Claims (6)
1. there is Chinese medicine composition and the production technology thereof of enhancing immunity, it is characterized in that: the raw material comprising following parts by weight ratio: Rhizoma Dioscoreae 25 ~ 50 parts, the Radix Astragali 25 ~ 50 parts, Radix Panacis Quinquefolii 2 ~ 5 parts.
2. there is Chinese medicine composition and the production technology thereof of enhancing immunity, it is characterized in that must containing Rhizoma Dioscoreae in formula, select one or both in Radix Panacis Quinquefolii and Milkvetch Root simultaneously.
3. a production technology for the Chinese medicine composition as described in claim 1,2, makes tablet form.It is characterized in that production process is:
(1) clean: by Rhizoma Dioscoreae, Radix Panacis Quinquefolii, the Radix Astragali three taste medical material, removing impurity, rapid water cleans up, dry or cold drying.
(2) pulverize: 1/2 amount Rhizoma Dioscoreae in prescription is ground into 100 order fine powders, for subsequent use.
(3) extract: 1/2 amount Rhizoma Dioscoreae in prescription is extracted twice with Radix Astragali mixing decocting in water by (1), and amount of water is respectively 8 ~ 10 times, 6 ~ 8 times of medical material amount, and extraction time is 45 ~ 60 minutes, 30 ~ 45 minutes, filter, obtain extracting solution.Extracting solution is condensed into the thick paste that relative density is 1.20 ~ 1.30, for subsequent use.(2) by 8 ~ 10 times 60% ethanol percolation of Radix Panacis Quinquefolii by medical material amount, reclaim ethanol, be condensed into thick paste, for subsequent use.
(4) granulation, drying: the thick paste extracted with Radix Astragali mixing thick paste, Radix Panacis Quinquefolii by the Rhizoma Dioscoreae of the Rhizoma Dioscoreae powder pulverized, water extraction, adds appropriate adjuvant, make granule, 60 DEG C ~ 70 DEG C dryings.
(5) tabletting: after adding appropriate magnesium stearate mixing in dried particles, tabletting.
(6) pack: the tablet pressed is loaded plastic drug package, sealing.Finished product is obtained after adding outer package.Finished product, through after the assay was approved, is preserved in the dry storehouse in cool place.
4. a production technology for the Chinese medicine composition as described in claim 1,2, is characterized in that: made into particulate form, and method is substantially with described in claim 3, difference is the step eliminating tabletting, adds suitable adjuvant, makes sugary or sugar-free granule, packed, outer package obtains finished product.Every packed amount 3g ~ 15g.
5. a production technology for the Chinese medicine composition as described in claim 1,2, makes form of hard gelatin capsules, it is characterized in that: make granule or powder; method is substantially with described in claim 3, and difference is the step eliminating tabletting, loads hard capsule; packaging, outer package obtains finished product.
6. the production technology of the Chinese medicine composition as described in claim 1,2, it is characterized in that: make Oral liquid forms, method substantially with described in claim 3, difference be full dose medical material to extract respectively concentrated after the thick paste thin up that obtains, aseptic subpackaged, outer package obtains finished product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113797270A (en) * | 2021-09-23 | 2021-12-17 | 江西中医药健康产业研究院 | Vaccine mate and preparation method thereof |
| CN114794477A (en) * | 2022-04-29 | 2022-07-29 | 青海师范大学 | Composition for resisting fatigue and improving immunity and preparation method thereof |
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| CN101156928A (en) * | 2006-03-12 | 2008-04-09 | 李佳旺 | A Subhealth treating Chinese medicine composition and method of making the same |
| CN102273629A (en) * | 2011-08-18 | 2011-12-14 | 高益槐 | Health-care food for enhancing immunity and preparation method thereof |
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2014
- 2014-03-25 CN CN201410112436.XA patent/CN104940512A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101156928A (en) * | 2006-03-12 | 2008-04-09 | 李佳旺 | A Subhealth treating Chinese medicine composition and method of making the same |
| CN102273629A (en) * | 2011-08-18 | 2011-12-14 | 高益槐 | Health-care food for enhancing immunity and preparation method thereof |
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| 李军红著: "《李军红说 新妇科千金方》", 31 December 2011 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113797270A (en) * | 2021-09-23 | 2021-12-17 | 江西中医药健康产业研究院 | Vaccine mate and preparation method thereof |
| CN113797270B (en) * | 2021-09-23 | 2022-09-06 | 江西中医药健康产业研究院 | Traditional Chinese medicine composition for improving neutralizing antibody level of population inoculated with novel coronavirus vaccine as well as preparation method and application of traditional Chinese medicine composition |
| CN114794477A (en) * | 2022-04-29 | 2022-07-29 | 青海师范大学 | Composition for resisting fatigue and improving immunity and preparation method thereof |
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Application publication date: 20150930 |