CN104857641A - Portable transcranial ultrasonic brain regulation and control instrument - Google Patents
Portable transcranial ultrasonic brain regulation and control instrument Download PDFInfo
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- CN104857641A CN104857641A CN201510200446.3A CN201510200446A CN104857641A CN 104857641 A CN104857641 A CN 104857641A CN 201510200446 A CN201510200446 A CN 201510200446A CN 104857641 A CN104857641 A CN 104857641A
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Abstract
Disclosed is a portable transcranial ultrasonic brain regulation and control instrument. The portable transcranial ultrasonic brain regulation and control instrument comprises a portable ultrasonic signal emission handle, a focusing ultrasonic energy transducer, a helmet and an energy transducer fixing device, wherein the portable ultrasonic signal emission handle is connected with the focusing ultrasonic energy transducer, the energy transducer fixing device is a hollow threaded rod, one end of the hollow threaded rod is provided with a handle, the other end of the hollow threaded rod is fixedly connected with a sleeve, the helmet is in threaded connection with the hollow threaded rod of the energy transducer fixing device through a center through hole, and the focusing ultrasonic energy transducer is connected with the energy transducer fixing device through threads at an upper end and the sleeve. The portable transcranial ultrasonic brain regulation and control instrument is small in volume, simple to operate, convenient to carry and convenient to use, and can rapidly and conveniently realize low-power high-resolution and atraumatic ultrasonic brain regulation and control.
Description
Technical field the invention belongs to medical instruments field, particularly the ultrasonic brain adjusting and control instrument of one.
Background technology nervous system disease comprises maincenter and peripheral nervous disease, shows as the delayed ischemic neurological deficits such as sensation, consciousness, motion, causes comprising epilepsy, apoplexy, parkinson disease, Alzheimer and migraine etc.Ten are ranked before disease death ranking list according to the data display nervous system disease announced CDC in May, 2012.Nervous system disease has had a strong impact on the quality of life of patients and family, causes heavy financial burden to family and society simultaneously.
At present existing various wounds or atraumatic cerebral cortex stimulating technology are applied to laboratory and clinical, but these technology respectively have its limitation.Pharmaceutical chemistry treatment nervous system disease obtains certain effect, but lacks the specificity of target tissue, and spatial resolution is not high, also has certain side effect to human body.Other brain physical regulating technology, as electrical stimulus patterns, deep brain stimulation, then by being directly inserted in cerebral tissue by electrode, have higher spatial resolution, but operation exists greater risk.Atraumatic cortex stimulating technology conventional at present has transcranial magnetic stimulation, and need not carry out operation of opening cranium, safety is high, but the spatial resolution of stimulant is not high.Ultrasonicly can import human multiple tissue into by the form of pulse, low-strength focusing ultrasonic ripple acts on nervous system through skull, produce bio-mechanical effect to neuron, affect the nerves electrical activity, thus cause the not damaged brain control technique of a series of biochemical reactions.TCD,transcranial Doppler brain control technique meets the requirement simultaneously simple to operate of not damaged, high spatial resolution, the high-penetration degree of depth.
TCD,transcranial Doppler brain control technique obtains in recent years and develops fast, number of patent application is: 201210576849.4, name is called: the device and method that patent discloses the function of a kind of TCD,transcranial Doppler stimulation reparation cranial nerve of " TCD,transcranial Doppler stimulates the device and method repairing cranial nerve function ", this device comprises function signal generator, power amplifier and ultrasonic transducer, wherein, after this function signal generator produces the stimulus signal needed for stimulating, the high-voltage pulse signal needed for this ultrasonic transducer is amplified to by this power amplifier, then obtain ultrasound stimulation signal by this ultrasonic transducer, to stimulate cerebral tissue, but this device all parts disperses, equipment volume is large, ultrasonic transducer can not be fixed on the weak tendencies such as head, conveniently can not realize the regulation and control of ultrasonic brain.
Summary of the invention the object of the present invention is to provide the portable TCD,transcranial Doppler brain adjusting and control instrument that a kind of volume is little, easy and simple to handle, conveniently can regulate focal position, ensure control accuracy.
The present invention includes portable ultraphonic signal and launch handle, focused transducer, the helmet, transducer fixture.Wherein said portable ultraphonic is launched handle inner and is made up of signal transmission cards and power amplifier, handle is provided with switch, energy adjustment, fundamental frequency regulates, primitive period number regulates and pulse recurrence frequency regulates five buttons, this handle is connected with focused transducer by coaxial connecting line, described transducer fixture is a cannulated threaded bar, handle is provided with in one end of this cannulated threaded bar, its other end and a sleeve are connected, and are provided with screw thread in this sleeve; The described helmet is half spherical steel structure, helmet edge is provided with annulus, for the helmet is fixed on head, and ensure there is space between the helmet and skull for placing ultrasonic transducer, the corresponding different brain district of this helmet surface is also provided with some threaded circular holes, by this through hole, the helmet is screwed on the cannulated threaded bar of transducer fixture, and scalable upper-lower height and the regulation and control to Different brain region.The upper end of focused transducer is provided with screw thread, and this focused transducer is connected with transducer fixture by above-mentioned sleeve, and transducer fixture can drive focused transducer to be elevated by rotating handles, realizes the regulation and control of different depth brain.
The output fundamental frequency that described portable ultraphonic signal launches handle is the pulse signal of 0.3MHz-10MHz, and the parameter of the pulse signal of transmitting is the primitive period number that individual pulse comprises is 10-500, and pulse recurrence frequency is 100Hz-5KHz.Portable ultraphonic is launched handle and is used for sending impulse ultrasound signal, and focused transducer receives the pulse ultrasonic wave of transmitting focusing after pulse signal, regulates and controls for cranial nerve.
The focusing length of described ultrasonic transducer is greater than 30mm.
Described helmat belt at the head of people, by hand propelled focused transducer is moved in rotatable transducer fixture, until touch the medical supersonic couplant that scalp is smeared; Ultrasound wave, after the ultrasonic coupling medium being coated in scalp, acts on through skull and head nerves, causes nervous physiology to change by ultra sonic machinery effect.Stimulating precision for improving in brain regulation process, the focused transducer of different degree of focus can be changed, can also by hand propelled focused transducer being moved up and down the different brain district of regulation and control in rotatable transducer fixture.
The present invention compared with prior art compares tool and has the following advantages:
1, compact, easy and simple to handle, be easy to carry, easy to use.
2, conveniently can regulate focal position, ensure control accuracy, realize low-power, high-resolution quickly and easily, AT TCD,transcranial Doppler brain regulation and control.
Accompanying drawing explanation
Fig. 1 is structural representation sketch of the present invention;
Fig. 2 is the simplified schematic diagram of focused transducer in the present invention;
Fig. 3 is the simplified schematic diagram of transducer fixture in the present invention;
Fig. 4 is the simplified schematic diagram of the helmet in the present invention.
In figure: 1 portable ultraphonic signal launches handle, 2 focused transducers, 2-1 screw thread, 3 transducer fixtures, 3-1 handle, 3-2 cannulated threaded bar, 3-3 sleeve inner screw thread, 4 helmets, 4-1 circular hole, 4-2 screw thread, 4-3 annulus, sleeve 5.
Detailed description of the invention
In the portable TCD,transcranial Doppler brain adjusting and control instrument schematic diagram shown in Fig. 1, portable ultraphonic is launched handle 1 and is provided with switch, energy adjustment, fundamental frequency regulates, primitive period number regulates and pulse recurrence frequency regulates five buttons, this handle inner is made up of signal transmission cards (model DAPING-30) and power amplifier (model DAHAN-220F), the focused transducer 2 that this handle is DAPING-F30 by coaxial connecting line and model is connected, transducer fixture 3 is a cannulated threaded bar 3-2, handle 3-1 is provided with in one end of this cannulated threaded bar, its other end and a sleeve 5 are connected, screw thread 3-3 is provided with in this sleeve, the described helmet 4 is half spherical steel structure, helmet edge is provided with annulus 4-3, and for the helmet is fixed on head, the corresponding different brain district of this helmet surface is also provided with some threaded circular hole 4-1, by this through hole, the helmet is screwed on the cannulated threaded bar of transducer fixture, the focusing length of described focused transducer is 45mm, its upper end is provided with screw thread 2-1, this focused transducer is connected with transducer fixture by above-mentioned sleeve, transducer fixture can drive focused transducer to be elevated by rotating handles, realizes the regulation and control of different depth brain.
The output fundamental frequency that described portable ultraphonic signal launches handle is the pulse signal of 0.3MHz-10MHz, and the parameter of the pulse signal of transmitting is the primitive period number that individual pulse comprises is 10-500, and pulse recurrence frequency is 100Hz-5KHz.
Claims (4)
1. a portable TCD,transcranial Doppler brain adjusting and control instrument, it comprises portable ultraphonic signal and launches handle, focused transducer, the helmet, transducer fixture, it is characterized in that: described portable ultraphonic is launched handle and is connected with focused transducer by coaxial connecting line, described transducer fixture is a cannulated threaded bar, handle is provided with in one end of this cannulated threaded bar, its other end and a sleeve are connected, and are provided with screw thread in this sleeve; The described helmet is half spherical steel structure, this helmet edge is provided with annulus, the corresponding different brain district of this helmet surface is also provided with some threaded circular holes, by this through hole, the helmet is screwed on the cannulated threaded bar of transducer fixture, the upper end of focused transducer is provided with screw thread, and this focused transducer is threaded with transducer fixture by above-mentioned sleeve.
2. one according to claim 1 portable TCD,transcranial Doppler brain adjusting and control instrument, it is characterized in that: described portable ultraphonic is launched handle inner and is made up of signal transmission cards and power amplifier, handle is provided with switch, energy adjustment, fundamental frequency regulates, primitive period number regulates and pulse recurrence frequency regulates five buttons.
3. one according to claim 1 portable TCD,transcranial Doppler brain adjusting and control instrument, it is characterized in that: the output fundamental frequency that described portable ultraphonic signal launches handle is the pulse signal of 0.3MHz-10MHz, the parameter of the pulse signal launched is the primitive period number that individual pulse comprises is 10-500, and pulse recurrence frequency is 100Hz-5KHz.
4. one according to claim 1 portable TCD,transcranial Doppler brain adjusting and control instrument, is characterized in that: the focusing length of described ultrasonic transducer is greater than 30mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510200446.3A CN104857641A (en) | 2015-04-24 | 2015-04-24 | Portable transcranial ultrasonic brain regulation and control instrument |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510200446.3A CN104857641A (en) | 2015-04-24 | 2015-04-24 | Portable transcranial ultrasonic brain regulation and control instrument |
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| CN104857641A true CN104857641A (en) | 2015-08-26 |
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| CN201510200446.3A Pending CN104857641A (en) | 2015-04-24 | 2015-04-24 | Portable transcranial ultrasonic brain regulation and control instrument |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105943031A (en) * | 2016-05-17 | 2016-09-21 | 西安交通大学 | Wearable transcranial ultrasound nerve stimulation and electrophysiological recording combined system and method |
| CN105944245A (en) * | 2016-05-31 | 2016-09-21 | 深圳先进技术研究院 | Head-mounted ultrasonic transducer |
| WO2017063172A1 (en) * | 2015-10-15 | 2017-04-20 | 法玛科技顾问股份有限公司 | Ultrasound stimulation helmet |
| CN110639134A (en) * | 2019-09-30 | 2020-01-03 | 秦皇岛市第一医院 | Ultrasonic probe adjusting device, ultrasonic probe adjusting method and transcranial nerve stimulator |
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| CN1689662A (en) * | 2004-04-30 | 2005-11-02 | 郎鸿志 | Via-skull stereo directed ultrasonic thrombolysis therapeutic apparatus |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2017063172A1 (en) * | 2015-10-15 | 2017-04-20 | 法玛科技顾问股份有限公司 | Ultrasound stimulation helmet |
| US10940335B2 (en) | 2015-10-15 | 2021-03-09 | National Yang-Ming University | Ultrasound stimulation helmet |
| CN105943031A (en) * | 2016-05-17 | 2016-09-21 | 西安交通大学 | Wearable transcranial ultrasound nerve stimulation and electrophysiological recording combined system and method |
| CN105944245A (en) * | 2016-05-31 | 2016-09-21 | 深圳先进技术研究院 | Head-mounted ultrasonic transducer |
| CN110639134A (en) * | 2019-09-30 | 2020-01-03 | 秦皇岛市第一医院 | Ultrasonic probe adjusting device, ultrasonic probe adjusting method and transcranial nerve stimulator |
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