CN104604934A - Novel composite iodine disinfectant as well as preparation method and application thereof - Google Patents
Novel composite iodine disinfectant as well as preparation method and application thereof Download PDFInfo
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Abstract
The invention provides a novel composite iodine disinfectant as well as a preparation method and an application thereof. The novel composite iodine disinfectant is prepared from raw materials, including quaternary ammonium salt, iodine, potassium iodate, inorganic acid and water, in percentage by weight. The preparation method comprises steps as follows: firstly, the quaternary ammonium salt, the inorganic acid and the water are mixed, heated and heat-insulated, then the iodine and the potassium iodate are added, and a continuous heat-insulation mixing reaction is conducted until the iodine is completely dissolved. The composite iodine disinfectant has characteristics of the high sterilization speed and the high efficiency of iodine disinfectants as well as the characteristic of long sterilization and bacteriostatic duration of quaternary ammonium salt disinfectants, so that the usage frequency can be reduced. The preparation method is simple, the technological process is simple and easy to control, the production cycle is short, the production cost is low, and the method is suitable for industrial production. The composite iodine disinfectant can be used as a sterilization product applied to preparation of main components and is good in stability, non-toxic and non-irritating; the composite iodine disinfectant can also be applied to sterilization of animal husbandry and aquaculture and is good in sterilization and bacteriostatic effect.
Description
Technical field
The present invention relates to disinfectant technical field, a kind of NEW TYPE OF COMPOSITE iodine disinfectant of particularly livestock breeding sterilization and aquatic products industry sterilization use and its preparation method and application.
Background technology
In order to reach sterilisation purpose to pollutant, different classes of, different dosage form, different efficacies iodine sterile products is just being widely used in the aspects such as health, daily life, agriculture and animal husbandry aquaculture and drinking water, now widely used disinfectant is mainly iodine class, quaternary ammonium salt, and chloride class disinfectant, but in actual use, there is defect clearly in single disinfectant, as: quaternary ammonium disinfectant bactericidal effect is poor, working concentration is high, although containing iodine and chlorine-containing disinfectant bactericidal effect good, the duration is short, and frequency of utilization is high.Therefore, occurred quaternary ammonium salt chelated iodine disinfectant, have bactericidal effect good and duration long advantage concurrently, but existing quaternary ammonium salt chelated iodine existence and stability has been poor, the drawback that the rate of recovery of iodine is low, result in resource wastes greatly.
Summary of the invention
For above-mentioned defect and the problem of prior art, the object of this invention is to provide a kind of NEW TYPE OF COMPOSITE iodine disinfectant and preparation method thereof, NEW TYPE OF COMPOSITE iodine disinfectant is quaternary ammonium salt chelated iodine disinfectant, good stability, and bactericidal effect is good, and the duration is long; And preparation method is simple.Solve existing quaternary ammonium salt chelated iodine existence and stability poor, the technical problem that the rate of recovery of iodine is low.
In order to achieve the above object, the invention provides following technical scheme:
A kind of NEW TYPE OF COMPOSITE iodine disinfectant, percentage by weight, by comprise 5% ~ 60% quaternary ammonium salt, 0.1% ~ 5% iodine, the Potassiumiodate of 0 ~ 0.5%, the inorganic acid of 1% ~ 25% and excess water raw material make.
Further, percentage by weight, by comprise 30% ~ 50% quaternary ammonium salt, 1% ~ 3% iodine, the Potassiumiodate of 0.01 ~ 0.1%, the inorganic acid of 5% ~ 25% and excess water raw material make.
Further, percentage by weight, by comprise 50% quaternary ammonium salt, 2.1% iodine, the Potassiumiodate of 0.05%, the inorganic acid of 22% and excess water raw material make.
Further, described quaternary ammonium salt is dication quaternary ammonium salt.
Particularly, the chemistry of dication quaternary ammonium salt is called 2-hydroxy-n-Alkyl-methyl propane-1,3 ammonium chloride, and its structural formula is as follows:
wherein R
1, R
2the carbon chain lengths of group is 1 ~ 16 carbon atom.Preferably, R
1the carbon chain lengths of group is 1 carbon atom, R
2the carbon chain lengths of group is 12 carbon atoms.
Further, described inorganic acid is phosphoric acid and/or hydrochloric acid.When inorganic acid is the mixture of phosphoric acid and hydrochloric acid, both are with arbitrarily than mixing.
The preparation method of a kind of NEW TYPE OF COMPOSITE iodine disinfectant of the present invention, is realized by following steps: percentage by weight, takes each raw material; Quaternary ammonium salt, inorganic acid and water are added in reactor, while stirring, is heated to 40 DEG C ~ 80 DEG C, insulation; Continue to stir, add iodine and Potassiumiodate, then insulation reaction is dissolved completely to iodine, and cooling, obtains NEW TYPE OF COMPOSITE iodine disinfectant.
The application of a kind of NEW TYPE OF COMPOSITE iodine disinfectant of the present invention in aquatic products industry sterilization.
The application of a kind of NEW TYPE OF COMPOSITE iodine disinfectant of the present invention in livestock breeding sterilization.
The quaternary ammonium salt chelated iodine disinfectant that NEW TYPE OF COMPOSITE iodine disinfectant of the present invention is a kind of new green environment protection, efficient stable is good.Both there is the feature that the fast efficiency of sterilization speed sterilization degree of iodine class disinfectant is high, there is again the feature of quaternary ammonium disinfectant bactericidal duration length, thus the effect reducing frequency of utilization can be reached.The interpolation of inorganic acid in NEW TYPE OF COMPOSITE iodine disinfectant of the present invention (or Potassiumiodate and inorganic acid), makes there is excessive H in whole system
+ion (or IO
3 -ion and H
+ion), the disproportionated reaction (I that iodine is occurred in water
2+ 3H2O=5HI+HIO
3), can not to forward reaction, thus the stability of iodine be improved, the iodine rate of recovery be high, reaches more than 99%.Its preparation method is simple, and technical process is simple, and easily control, with short production cycle, production cost is low, is applicable to suitability for industrialized production.
Good stability, the usability of the disinfection product prepared for key component with NEW TYPE OF COMPOSITE iodine disinfectant of the present invention are good, dissolubility is good, use cost is low, safety and environmental protection, and the feature of easily degraded, belongs to nontoxic non-irritating Green Product.
NEW TYPE OF COMPOSITE iodine disinfectant of the present invention, sterilization and good antimicrobial effect, all have good sterilization and fungistatic effect to Candida albicans, Escherichia coli, golden yellow glucose fungus etc.
Embodiment
Below in conjunction with embodiments of the invention, be clearly and completely described technical scheme of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
NEW TYPE OF COMPOSITE iodine disinfectant, by weight percentage, by comprise 60% dication quaternary ammonium salt, the iodine of 3%, the phosphoric acid of 1% and surplus the raw material of water make.
Described dication quaternary ammonium salt is 2-hydroxy-n-Alkyl-methyl propane-1,3 ammonium chloride, and its structural formula is as follows:
r
1the carbon chain lengths of group is 1 carbon atom, R
2the carbon chain lengths of group is 12 carbon atoms.Its synthetic method is shown in the content recorded in embodiment 8.
NEW TYPE OF COMPOSITE iodine disinfectant preparation method is: by above-mentioned percetage by weight, takes each raw material; Dication quaternary ammonium salt, phosphoric acid and water are added in reactor, while stirring, is heated to 40 DEG C, insulation, continue to stir after improving mixing speed, add iodine, insulated and stirred reacts 6 hours afterwards, dissolve completely to iodine, cooling, obtains the NEW TYPE OF COMPOSITE iodine disinfectant of embodiment 1.
Embodiment 2
NEW TYPE OF COMPOSITE iodine disinfectant, by weight percentage, by comprise 60% dication quaternary ammonium salt, the iodine of 5%, the phosphoric acid of 5% and surplus the raw material of solvent make.Described solvent is water and ethylene glycol, and wherein ethylene glycol accounts for 3% in the feed, and water accounts for 12%.
Described dication quaternary ammonium salt adopts 2-hydroxy-n-Alkyl-methyl propane-1,3 ammonium chloride recorded in embodiment 1.
NEW TYPE OF COMPOSITE iodine disinfectant preparation method is: by above-mentioned percetage by weight, takes each raw material; Dication quaternary ammonium salt, phosphoric acid, ethylene glycol and water are added in reactor, while stirring, is heated to 40 DEG C, insulation, continue to stir after improving mixing speed, add iodine, insulated and stirred reacts 6 hours afterwards, dissolve completely to iodine, cooling, obtains the NEW TYPE OF COMPOSITE iodine disinfectant of embodiment 2.
Embodiment 3
NEW TYPE OF COMPOSITE iodine disinfectant, by weight percentage, by comprise 30% dication quaternary ammonium salt, 1.6% iodine, the phosphoric acid of 1%, the hydrochloric acid of 5% and surplus the raw material of alcohol solvent make.
Described dication quaternary ammonium salt adopts 2-hydroxy-n-Alkyl-methyl propane-1,3 ammonium chloride recorded in embodiment 1.
NEW TYPE OF COMPOSITE iodine disinfectant preparation method is: by above-mentioned percetage by weight, takes each raw material; Dication quaternary ammonium salt, phosphoric acid, hydrochloric acid and ethanol are added in reactor, while stirring, is heated to 60 DEG C, insulation, continue to stir after improving mixing speed, add iodine, insulated and stirred reacts 2 hours afterwards, dissolve completely to iodine, cooling, obtains the NEW TYPE OF COMPOSITE iodine disinfectant of embodiment 3.
Embodiment 4
NEW TYPE OF COMPOSITE iodine disinfectant, by weight percentage, by comprise 50% dication quaternary ammonium salt, 1.05% iodine, the phosphoric acid of 0.5%, the hydrochloric acid of 5% and surplus the raw material of ethylene glycol solvent make.
Described dication quaternary ammonium salt adopts 2-hydroxy-n-Alkyl-methyl propane-1,3 ammonium chloride recorded in embodiment 1.
NEW TYPE OF COMPOSITE iodine disinfectant preparation method is: by above-mentioned percetage by weight, takes each raw material; Dication quaternary ammonium salt, phosphoric acid, hydrochloric acid and ethylene glycol are added in reactor, while stirring, is heated to 80 DEG C, insulation, continue to stir after improving mixing speed, add iodine, insulated and stirred reacts 4 hours afterwards, dissolve completely to iodine, cooling, obtains the NEW TYPE OF COMPOSITE iodine disinfectant of embodiment 4.
Embodiment 5
NEW TYPE OF COMPOSITE iodine disinfectant, by weight percentage, by comprise 50% dication quaternary ammonium salt, 1.05% iodine, 0.05% Potassiumiodate, the phosphoric acid of 0.5%, the hydrochloric acid of 5% and surplus the raw material of ethylene glycol solvent make.
Described dication quaternary ammonium salt adopts 2-hydroxy-n-Alkyl-methyl propane-1,3 ammonium chloride recorded in embodiment 1.
NEW TYPE OF COMPOSITE iodine disinfectant preparation method is: by above-mentioned percetage by weight, takes each raw material; Dication quaternary ammonium salt, phosphoric acid, hydrochloric acid and ethylene glycol are added in reactor, 80 DEG C are heated to while stirring, insulation, continue to stir after improving mixing speed, add iodine and Potassiumiodate, insulated and stirred reacts 4 hours afterwards, dissolves completely to iodine, cooling, obtains the NEW TYPE OF COMPOSITE iodine disinfectant of embodiment 5.
Embodiment 6
NEW TYPE OF COMPOSITE iodine disinfectant, by weight percentage, by comprise 50% dication quaternary ammonium salt, 2.1% iodine, 0.05% Potassiumiodate, 20% phosphoric acid, 2% hydrochloric acid, the ethanol of 1%, the ethylene glycol of 6% and surplus the raw material of water make.Solvent comprises ethanol, ethylene glycol and water.
Described dication quaternary ammonium salt adopts 2-hydroxy-n-Alkyl-methyl propane-1,3 ammonium chloride recorded in embodiment 1.
NEW TYPE OF COMPOSITE iodine disinfectant preparation method is: by above-mentioned percetage by weight, takes each raw material; Dication quaternary ammonium salt, phosphoric acid, hydrochloric acid, ethanol, ethylene glycol and water are added in reactor, 40 DEG C are heated to while stirring, insulation, continue to stir after improving mixing speed, add iodine and Potassiumiodate, insulated and stirred reacts 5 hours afterwards, dissolves completely to iodine, cooling, obtains the NEW TYPE OF COMPOSITE iodine disinfectant of embodiment 6.
Embodiment 7 contrast experiment example does not add inorganic acid
NEW TYPE OF COMPOSITE iodine disinfectant, by weight percentage, by comprise 50% dication quaternary ammonium salt, 2.1% iodine, 0.05% Potassiumiodate, the ethanol of 1%, the ethylene glycol of 6% and surplus the raw material of water make.Solvent comprises ethanol, ethylene glycol and water.
Described dication quaternary ammonium salt adopts 2-hydroxy-n-Alkyl-methyl propane-1,3 ammonium chloride recorded in embodiment 1.
NEW TYPE OF COMPOSITE iodine disinfectant preparation method is: by above-mentioned percetage by weight, takes each raw material; Dication quaternary ammonium salt, ethanol, ethylene glycol and water are added in reactor, 40 DEG C are heated to while stirring, insulation, continue to stir after improving mixing speed, add iodine and Potassiumiodate, insulated and stirred reacts 5 hours afterwards, dissolves completely to iodine, cooling, obtains the NEW TYPE OF COMPOSITE iodine disinfectant of embodiment 7.
Embodiment 8
The synthetic method of the dication quaternary ammonium salt (2-hydroxy-n-Alkyl-methyl propane-1,3 ammonium chloride) adopted in above-described embodiment 1 to embodiment 7 is as follows:
Step one, by weight, take the raw material comprising 100 parts of Dodecyl Dimethyl Amines, 50 parts of epoxychloropropane, 45 parts of trimethylamine hydrochlorides, 0.05 ~ 0.2 part of complexing agent and 50 ~ 200 parts of water;
Step 2, trimethylamine hydrochloride, complexing agent and water are added in reactor, after mixing, then add Dodecyl Dimethyl Amine, stir, obtain mixed reactant;
Step 3, mixed reactant is heated to 75 DEG C ~ 85 DEG C, insulation, then drips epoxychloropropane, controls to dropwise in 1 hour in mixed reactant; Then at the temperature range inside holding stirring reaction 2 ~ 4 hours of 78 DEG C ~ 82 DEG C; Obtain 2-hydroxy-n-Alkyl-methyl propane-1,3 ammonium chloride.
The present invention carries out the mensuration of available iodine content and quaternary ammonium salt content after the NEW TYPE OF COMPOSITE iodine disinfectant of embodiment 1 to embodiment 7 is placed different time to it.Determination data sees the following form 1.
Wherein, determination of the content of iodine: the NEW TYPE OF COMPOSITE iodine disinfectant 10g of Example 1 to embodiment 7 respectively, accurately weighed, put in iodine flask, the 50mL that adds water makes it to dissolve completely, be titrated to colourless with sodium thiosulfate titrating solution (0.1mol/L), every 1ml sodium thiosulfate titrating solution (0.1mol/L) is equivalent to the I of 12.69mg
2.
Quaternary ammonium salt assay: precision takes the NEW TYPE OF COMPOSITE iodine disinfectant 0.15g of embodiment 1 to embodiment 7, put in 250mL iodine flask, the 30mL that adds water makes dissolving, then adds sodium hydroxide test solution 1mL, chloroform 15mL, bromophenol blue indicator solution 0.5mL successively, and jolting is even.Use the titration of tetraphenylboron sodium titrating solution again, titration limit, limit forced oscillation is to the blueness in chloroform layer disappears.Record tetraphenylboron sodium titrating solution (0.02mol/L) consumes volume, and the tetraphenylboron sodium titrating solution (0.02mol/L) of every 1mL is equivalent to the double-chain quaternary ammonium salt of 7.23mg.
Table 1
Can draw from the detection data of table 1, in NEW TYPE OF COMPOSITE iodine disinfectant of the present invention, the rate of recovery of iodine can reach 100%, does not almost waste, and available iodine content only has with the resting period and slightly reduces, and stability is fine.
Application example 1
The application of NEW TYPE OF COMPOSITE iodine disinfectant of the present invention in aquatic products industry sterilization.To Candida albicans, Escherichia coli, golden yellow glucose fungus etc., all there is good sterilization and fungistatic effect.
Application example 2
The application of NEW TYPE OF COMPOSITE iodine disinfectant of the present invention in livestock breeding sterilization.To Candida albicans, Escherichia coli, golden yellow glucose fungus etc., all there is good sterilization and fungistatic effect.
The present invention adopts the NEW TYPE OF COMPOSITE iodine disinfectant sample of embodiment 5 to carry out sterilization experiment, carries out fungi killing test respectively to Candida albicans, Escherichia coli and Staphylococcus aureus.Employing Matsubain in the last of the ten Heavenly stems does parallel contrast experiment with the existing disinfectant sample of povidone iodine two kinds simultaneously.The neutralizer adopted in experiment is 0.5%Na
2s
2o
3the PBS solution of the 0.03mol/L of+0.7% lecithin+2% Tween-80.Test basis is that " disinfection technology standard " (version in 2002) 2.1.1.9 saves the content recorded.Experimental result is respectively as shown in following table 2, table 3 and table 4.
Table 2 Candida albicans sterilization experiment result
According to the experimental data that above-mentioned table 2 provides, during sterilization logarithm value >5, the last of the ten Heavenly stems Matsubain and povidone iodine be used alone least concentration be respectively 1000mg/L act on 10 minutes and 50mg/L act on 10 minutes.And the NEW TYPE OF COMPOSITE iodine disinfectant of the embodiment of the present invention 5 (dication quaternary ammonium salt and iodine press the composite complexing of 20:1), be 12.5mg/L at iodine concentration, when quaternary ammonium salt concentration is 250mg/L, effect can reach the sterilization logarithm value of >5 for 10 minutes.Therefore, in sterilization experiment, the present invention has good sterilization and bacteriostasis effect to Candida albicans.
Table 3, Escherichia coli sterilization experiment result
According to the experimental data that above-mentioned table 3 provides, during sterilization logarithm value >5, the last of the ten Heavenly stems Matsubain and povidone iodine be used alone least concentration be respectively 1000mg/L act on 10 minutes and 50mg/L act on 10 minutes.And the NEW TYPE OF COMPOSITE iodine disinfectant of the embodiment of the present invention 5 (dication quaternary ammonium salt and iodine press the composite complexing of 20:1), be 12.5mg/L at iodine concentration, when surfactant concentration is 312.5mg/L, effect can reach the sterilization logarithm value of >5 for 10 minutes.Therefore, in sterilization experiment, the present invention has good sterilization and bacteriostasis effect to Escherichia coli.
Table 4 Staphylococcus aureus sterilization experiment result
According to the experimental data of above-mentioned table 4, during sterilization logarithm value >5, the last of the ten Heavenly stems Matsubain and povidone iodine be used alone least concentration be respectively 1500mg/L act on 10 minutes and 75mg/L act on 10 minutes.And the NEW TYPE OF COMPOSITE iodine disinfectant of the embodiment of the present invention 5 (dication quaternary ammonium salt and iodine press the composite complexing of 20:1), be 25mg/L at iodine concentration, when surfactant concentration is 500mg/L, effect can reach the sterilization logarithm value of >5 for 10 minutes.Therefore, in sterilization experiment, the present invention has good sterilization and bacteriostasis effect to Staphylococcus aureus.
Therefore, NEW TYPE OF COMPOSITE iodine disinfectant bactericidal effect of the present invention be better than independent povidone iodine or the last of the ten Heavenly stems Matsubain bactericidal effect, can be applied in livestock breeding sterilization and aquatic products industry sterilization, to Candida albicans, Escherichia coli, golden yellow glucose fungus etc., all there is good sterilization and fungistatic effect.
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; change can be expected easily or replace, all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should described be as the criterion with the protection domain of claim.
Claims (10)
1. a NEW TYPE OF COMPOSITE iodine disinfectant, is characterized in that: percentage by weight, by comprise 5% ~ 60% quaternary ammonium salt, 0.1% ~ 5% iodine, the Potassiumiodate of 0 ~ 0.5%, the inorganic acid of 1% ~ 25% and excess water raw material make.
2. a kind of NEW TYPE OF COMPOSITE iodine disinfectant according to claim 1, it is characterized in that: percentage by weight, by comprise 30% ~ 50% quaternary ammonium salt, 1% ~ 3% iodine, the Potassiumiodate of 0.01 ~ 0.1%, the inorganic acid of 5% ~ 25% and excess water raw material make.
3. a kind of NEW TYPE OF COMPOSITE iodine disinfectant according to claim 1, is characterized in that: percentage by weight, by comprise 50% quaternary ammonium salt, 2.1% iodine, the Potassiumiodate of 0.05%, the inorganic acid of 22% and excess water raw material make.
4. according to a kind of NEW TYPE OF COMPOSITE iodine disinfectant one of claims 1 to 3 Suo Shu, it is characterized in that: described quaternary ammonium salt is dication quaternary ammonium salt.
5. a kind of NEW TYPE OF COMPOSITE iodine disinfectant according to claim 4, is characterized in that: the chemistry of described dication quaternary ammonium salt is called 2-hydroxy-n-Alkyl-methyl propane-1,3 ammonium chloride, and its structural formula is as follows:
wherein R
1, R
2the carbon chain lengths of group is 1 ~ 16 carbon atom.
6. a kind of NEW TYPE OF COMPOSITE iodine disinfectant according to claim 5, is characterized in that: R
1the carbon chain lengths of group is 1 carbon atom, R
2the carbon chain lengths of group is 12 carbon atoms.
7. a kind of NEW TYPE OF COMPOSITE iodine disinfectant according to claim 1,2,3,5 or 6, is characterized in that: described inorganic acid is phosphoric acid and/or hydrochloric acid; When inorganic acid is the mixture of phosphoric acid and hydrochloric acid, both are with arbitrarily than mixing.
8. the preparation method of a kind of NEW TYPE OF COMPOSITE iodine disinfectant as claimed in claim 1, be is characterized in that: realized by following steps: percentage by weight, takes quaternary ammonium salt, iodine, Potassiumiodate, inorganic acid and water; Quaternary ammonium salt, inorganic acid and water are added in reactor, while stirring, is heated to 40 DEG C ~ 80 DEG C, insulation; Continue to stir, add iodine and Potassiumiodate, then insulation reaction is dissolved completely to iodine, and cooling, obtains NEW TYPE OF COMPOSITE iodine disinfectant.
9. the application of a kind of NEW TYPE OF COMPOSITE iodine disinfectant as claimed in claim 1 in aquatic products industry sterilization.
10. the application of a kind of NEW TYPE OF COMPOSITE iodine disinfectant as claimed in claim 1 in livestock breeding sterilization.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106259442A (en) * | 2016-07-19 | 2017-01-04 | 成都科宏达科技有限公司 | A kind of compound disinfectant containing iodine |
| CN111035674A (en) * | 2020-03-06 | 2020-04-21 | 吉林云飞医药有限公司 | Aner iodine skin mucosa disinfectant as well as preparation method and application thereof |
| CN111328806A (en) * | 2020-03-07 | 2020-06-26 | 郑州大学 | Double-linear alkyl quaternary ammonium salt complex iodine bactericide |
| CN112841181A (en) * | 2020-12-31 | 2021-05-28 | 佛山市正典生物技术有限公司 | Stable iodine-containing disinfectant and preparation method thereof |
| US11297839B2 (en) | 2014-03-31 | 2022-04-12 | ioTech International, Incorporated | Stable compositions of uncomplexed iodine and methods of use |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1593150A (en) * | 2004-07-16 | 2005-03-16 | 哈尔滨工业大学 | Bi-dodecyl double quaternary ammonium salt iodine attached bactericide |
| CN101006790A (en) * | 2006-12-05 | 2007-08-01 | 段英利 | Refined iodine disinfectant liquor |
| CN101168511A (en) * | 2007-11-22 | 2008-04-30 | 江苏飞翔化工股份有限公司 | Method for preparing hydroxypropyl diquaternary ammonium salt |
| CN102531928A (en) * | 2011-12-15 | 2012-07-04 | 成都齐达水处理工程股份有限公司 | Asymmetric bis-quaternary ammonium salt as well as preparation method and application thereof |
| CN102550602A (en) * | 2010-11-30 | 2012-07-11 | 中国科学院成都有机化学有限公司 | High-iodine controlled-release type sanitizer |
| CN103891772A (en) * | 2014-04-21 | 2014-07-02 | 成都科宏达科技有限公司 | Compound sterilizing agent |
-
2015
- 2015-01-21 CN CN201510030080.XA patent/CN104604934B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1593150A (en) * | 2004-07-16 | 2005-03-16 | 哈尔滨工业大学 | Bi-dodecyl double quaternary ammonium salt iodine attached bactericide |
| CN101006790A (en) * | 2006-12-05 | 2007-08-01 | 段英利 | Refined iodine disinfectant liquor |
| CN101168511A (en) * | 2007-11-22 | 2008-04-30 | 江苏飞翔化工股份有限公司 | Method for preparing hydroxypropyl diquaternary ammonium salt |
| CN102550602A (en) * | 2010-11-30 | 2012-07-11 | 中国科学院成都有机化学有限公司 | High-iodine controlled-release type sanitizer |
| CN102531928A (en) * | 2011-12-15 | 2012-07-04 | 成都齐达水处理工程股份有限公司 | Asymmetric bis-quaternary ammonium salt as well as preparation method and application thereof |
| CN103891772A (en) * | 2014-04-21 | 2014-07-02 | 成都科宏达科技有限公司 | Compound sterilizing agent |
Non-Patent Citations (2)
| Title |
|---|
| 夏旖旎等，: ""一种不对称双季铵盐表面活性剂的合成"", 《精细石油化工》 * |
| 孔素东等,: ""双季铵盐类化合物的研究现状及合成进展"", 《化工中间体》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11297839B2 (en) | 2014-03-31 | 2022-04-12 | ioTech International, Incorporated | Stable compositions of uncomplexed iodine and methods of use |
| US11653653B2 (en) | 2014-03-31 | 2023-05-23 | Iotech International, Inc. | Stable compositions of uncomplexed iodine and methods of use |
| CN106259442A (en) * | 2016-07-19 | 2017-01-04 | 成都科宏达科技有限公司 | A kind of compound disinfectant containing iodine |
| CN111035674A (en) * | 2020-03-06 | 2020-04-21 | 吉林云飞医药有限公司 | Aner iodine skin mucosa disinfectant as well as preparation method and application thereof |
| CN111328806A (en) * | 2020-03-07 | 2020-06-26 | 郑州大学 | Double-linear alkyl quaternary ammonium salt complex iodine bactericide |
| CN112841181A (en) * | 2020-12-31 | 2021-05-28 | 佛山市正典生物技术有限公司 | Stable iodine-containing disinfectant and preparation method thereof |
| CN112841181B (en) * | 2020-12-31 | 2022-06-17 | 佛山市正典生物技术有限公司 | Stable iodine-containing disinfectant and preparation method thereof |
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| CN104604934B (en) | 2017-11-03 |
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