CN104391127B - A kind of in-vitro diagnosis test card adding mouth structure and in-vitro diagnosis test card - Google Patents
A kind of in-vitro diagnosis test card adding mouth structure and in-vitro diagnosis test card Download PDFInfo
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- CN104391127B CN104391127B CN201410637495.9A CN201410637495A CN104391127B CN 104391127 B CN104391127 B CN 104391127B CN 201410637495 A CN201410637495 A CN 201410637495A CN 104391127 B CN104391127 B CN 104391127B
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- test card
- elastic sealing
- sealing cover
- pool
- vitro diagnosis
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Abstract
A kind of in-vitro diagnosis test card adding mouth structure and in-vitro diagnosis test card, this test card includes elastic sealing cover and main body successively, described main body includes being formed at the reagent of elastic sealing cover side, sample pool and waste liquid pool, and is positioned at its each import of opposite side respectively by the unpacking mouth each reagent of connection and sample pool and the microfluidic channel of outlet waste liquid pool;Described sample pool adding mouth structure include its inwall formed described sample pool by the cylinder raised up, be positioned at the annular polyrrhea groove that this cylinder is peripheral, bottom polyrrhea groove, be formed with the through hole connected with described waste liquid pool;Described elastic sealing cover is provided with outside it and seals, with described sample pool polyrrhea groove outer wall, the annular protrusion coordinated.Use this structure, either with specific purpose tool such as liquid-transfering gun, or general utility tool such as syringe, can quantitatively load liquid;Surplus liquid a certain degree of can be prevented excessive, cause external contamination;Liquid in sample pool can be sealed.
Description
Technical field
The present invention relates to a kind of in-vitro diagnosis test card adding mouth structure and in-vitro diagnosis test card, particularly relate to one
Have quantitatively, seal, the in-vitro diagnosis test card of the liquid adding mouth structure of anti-overflow function.
Background technology
The liquid sample load ports (abbreviation adding mouth) of the test card diagnostic applied in the market, major part is all uncovered
, the most do not possess quantitatively and sealing function.To there being the adding mouth of quantitative requirement and seal request, the adding mouth of this class formation without
Method meets requirement.And there is the risk that liquid sample is revealed, such operator in the most uncovered adding mouth structure
It is necessary for careful ability permissible.Additionally must use specific purpose tool during sample-adding, if operator does not note somewhat adding multiple spot liquid,
Liquid then can be caused to overflow pollute.Additionally on market, also the adding mouth of some test card diagnostic has sealing lid, but does not has
There is quantitative function.
In order to solve the problems referred to above, the invention provides a kind of new have quantitatively, seal, the liquid of anti-overflow function adds
Sample mouth structure.
Use this structure, either with specific purpose tool (such as liquid-transfering gun) or general utility tool (such as syringe), all may be used
Quantitatively to load liquid;Surplus liquid a certain degree of can be prevented excessive, cause external contamination;Liquid in sample pool can be sealed
Body.
Summary of the invention
It is an object of the present invention to provide a kind of new have quantitatively, seal, the liquid adding mouth of anti-overflow function
Structure.
For reaching above-mentioned purpose, the present invention uses following technical proposals:
A kind of in-vitro diagnosis test card adding mouth structure, this test card includes elastic sealing cover and main body, described master successively
Body includes being formed at the reagent of elastic sealing cover side, sample pool and waste liquid pool, and is positioned at its each import of opposite side respectively
Each reagent and sample pool and the microfluidic channel of outlet waste liquid pool is connected by unpacking mouth;
Described adding mouth structure includes that its inwall forms the cylinder raised up of described sample pool, is positioned at this cylinder peripheral
Annular polyrrhea groove, be formed with the through hole connected with described waste liquid pool bottom polyrrhea groove;
Described elastic sealing cover is provided with inside it and seals, with described sample pool polyrrhea groove outer wall, the annular protrusion coordinated.
Preferably, one or more spill sump pit, its structure it are provided with inside the annular protrusion of described elastic sealing cover
In making sample pool, discharge flows in described polyrrhea groove.
Preferably, described elastic sealing cover is provided with its root and seals, with sample pool barrel top, the convex blistering coordinated
Platform.
Preferably, to include that elastic sealing cover, main body and bottom, described main body include being formed at successively elastic close for this test card
The capping reagent of side, sample pool and waste liquid pool, described elastic sealing cover is for sealing each reagent;
Described sample pool is formed by the inner surface of the cylinder raised up, and this cylinder periphery is provided with annular polyrrhea groove, overflows
The through hole connected with described waste liquid pool it is formed with bottom liquid bath;
This elastic sealing cover includes the sample basin lid relative to the turning unlatching of elastic sealing cover, and this sample basin lid is provided with
Seal, with described sample pool polyrrhea groove outer wall, the annular protrusion coordinated inside it.
Preferably, being provided with one or more spill sump pit inside the annular protrusion of described sample basin lid, its structure makes
In obtaining sample pool, discharge flows in described polyrrhea groove.When covering tightly elastic sealing cover, first elastic sealing cover can seal up discharge
Groove top, the partially liq in polyrrhea groove is discharged in waste liquid pool by through hole, prevents the leaked liquid in polyrrhea groove thus causes
External contamination.
Preferably, described sample basin lid is provided with its root and seals, with sample pool cylinder inner wall top, the convex blistering coordinated
Platform.
Preferably, described sample basin lid boss designs for undergauge.When covering tightly elastic sealing cover completely, boss can be unnecessary
Liquid be completely exhausted out, sample pool can be sealed by boss root simultaneously.Wherein the volume of liquid deducts convex equal to sample pool volume
The volume of platform.
Preferably, the annular protrusion of described sample basin lid is wedge shape.
Preferably, this test card farther includes for described elastic sealing cover is fixed top cover on the body,
This top cover has opening with described sample basin lid relevant position.
Preferably, described elastic sealing cover farther includes to overturn connecting portion, makes the described sample basin lid can be relative to described
Elastic sealing cover is independently opened.
Preferably, described top cover opening has for limiting upset connecting portion motion at elastic sealing cover upset connecting portion
Clamping structure.Sample basin lid upset connecting portion can fix the upset connecting portion in top cover correspondence sample basin lid by clamping structure
Opening part, facilitate operated by personnel.
Preferably, described top cover opening farther includes the multiple projections for compressing sample basin lid.When sample pool cover buckle
After conjunction, projection can block sample pool, it is ensured that sample pool will not unclamp.
Beneficial effects of the present invention is as follows:
1, this structure is used: either with specific purpose tool (such as liquid-transfering gun) or general utility tool (such as syringe), all
Can quantitatively load liquid;
2, use this structure, surplus liquid a certain degree of can be prevented excessive, cause external contamination;
3, use this structure, liquid in sample pool can be sealed.
Accompanying drawing explanation
Fig. 1 illustrates that one in-vitro diagnosis of the present invention tests card structure schematic diagram;
Fig. 2 illustrates a kind of in-vitro diagnosis of present invention test card main body schematic diagram near top cover side;
Fig. 3 illustrates a kind of in-vitro diagnosis of present invention test card main body schematic diagram near bottom side;
Fig. 4 illustrates that one in-vitro diagnosis of the present invention tests card adding mouth generalized section;
Fig. 5 illustrates axonometric chart when one in-vitro diagnosis of the present invention test card adding mouth elastic sealing cover is opened;
Fig. 6 illustrates top view and side-looking when one in-vitro diagnosis of the present invention test card adding mouth elastic sealing cover is opened
Figure;
Fig. 7 illustrates schematic diagram when one in-vitro diagnosis of the present invention test card adding mouth elastic sealing cover covers;
Fig. 8 illustrates that one in-vitro diagnosis of the present invention tests card adding mouth elastic sealing cover partial schematic diagram;
Fig. 9 illustrates that one in-vitro diagnosis of the present invention tests card top cover front schematic view;
Figure 10 A and B illustrates that one in-vitro diagnosis of the present invention tests card side schematic view;
Figure 11 A and B illustrates one in-vitro diagnosis of the present invention test card side partial schematic diagram.
Detailed description of the invention
In order to be illustrated more clearly that the present invention, below in conjunction with preferred embodiments and drawings, the present invention is done further
Bright.Parts similar in accompanying drawing are indicated with identical reference.It will be appreciated by those skilled in the art that institute is concrete below
The content described is illustrative and be not restrictive, and should not limit the scope of the invention with this.
Fig. 1 is the structural representation of a kind of in-vitro diagnosis test card.As it is shown in figure 1, this test card include successively top cover 1,
Including sealing lid 2, main body 3 and the fluid passage unit of elastic sealing gasket 4 formation, printed circuit board (PCB) 5, bottom 6.
Adding mouth structure includes that its inwall forms the cylinder raised up of sample pool, is positioned at the peripheral annular of this cylinder and overflows
Liquid bath, is formed with the through hole connected with described waste liquid pool bottom polyrrhea groove.Fig. 2 is that one in-vitro diagnosis of the present invention test card is close
The main body schematic diagram of top cover side.Fig. 3 is a kind of in-vitro diagnosis of present invention test card main body schematic diagram near bottom side.As
Shown in Fig. 2 and Fig. 3, in the present embodiment, the main body 3 of test card include being formed at the reagent 307 of elastic sealing cover side, 308,
309,310, sample pool 313 and waste liquid pool 311,312, and be positioned at its each import of bottom side respectively by unpacking mouth 301,
302,303,304 each reagent 307,308,309,310 and sample pool 313 and the microfluid of outlet waste liquid pool 312 are connected
Passage 314;Reagent and/or sample pool are formed by the inner surface of the cylinder raised up, and periphery is provided with annular polyrrhea groove.?
In the present embodiment, sample pool 313 periphery is provided with annular polyrrhea groove 315, is provided with through hole 305, discharge pond bottom annular polyrrhea groove 315
Through hole connected with waste liquid pool by import 306.
Fig. 4 is that one in-vitro diagnosis of the present invention tests card adding mouth generalized section.Fig. 5 is one in-vitro diagnosis of the present invention
Axonometric chart when test card elastic sealing cover is opened.Fig. 6 illustrates that one in-vitro diagnosis of the present invention tests card adding mouth elastic packing
Top view and side view when lid is opened.As shown in Fig. 4, Fig. 5, Fig. 6, in the present embodiment, sample pool 313 is positioned in main body 2, shape
The cylinder becoming sample pool has undergauge design structure from its opening to bottom, is with annular polyrrhea groove 315 outside it.Annular discharge
Trench bottom has through hole 306, connects (waste liquid pool not shown in figure) with waste liquid pool.A circle annular protrusion is had inside elastic sealing cover 2
202.The lateral wall of annular protrusion 202 seals with the outer wall of annular polyrrhea groove 315 and coordinates.The medial wall of annular protrusion 202 is formed
There is at least one sump pit 316.When elastic packing lid is provided with multiple sump pit, the most each sump pit is inside annular protrusion
Uniform setting.When elastic sealing cover covers with main body, in excessive liquid flows into polyrrhea groove 315 and by being formed at the bottom of polyrrhea groove
The through hole in portion is discharged in waste liquid pool, prevents the leaked liquid in polyrrhea groove 315 thus causes external contamination.Elastic sealing cover 2 is also
It is provided with its root and seals, with sample pool cylinder inner wall top, the internal projection boss coordinated.In the present embodiment, elastic sealing cover sets
Having boss 201 to be used as liquid discharge head, the root of boss seals with sample pool 313 and mates.When covering tightly elastic sealing cover, liquid discharge head
201 can enter in sample pool 313, are discharged in polyrrhea groove 315 by sump pit 316 by the surplus liquid in sample pool 313, then lead to
Cross through hole 305 row to waste liquid pool.When covering tightly sealing lid completely, then liquid discharge head 201 can be completely exhausted out unnecessary liquid, simultaneously
Sample pool can be sealed by liquid discharge head 201 root, and wherein the volume of liquid deducts the volume of liquid discharge head 201 equal to sample pool volume.
Fig. 7 illustrates schematic diagram when one in-vitro diagnosis of the present invention test card adding mouth elastic sealing cover covers.Fig. 8 illustrates this
Invention a kind of in-vitro diagnosis test card adding mouth elastic sealing cover partial schematic diagram.Fig. 9 illustrates that one in-vitro diagnosis of the present invention is surveyed
Examination card top cover front schematic view;Figure 10 illustrates that one in-vitro diagnosis of the present invention tests card side schematic view;Figure 11 illustrates the present invention
A kind of in-vitro diagnosis test card side partial schematic diagram.As shown in Fig. 7, Fig. 8, Fig. 9, Figure 10 and Figure 11, a kind of in-vitro diagnosis is surveyed
Examination card, its elastic sealing cover includes the sample basin lid relative to the turning unlatching of elastic sealing cover, and is provided with inside sample basin lid
Sample pool polyrrhea groove outer wall seals the annular protrusion coordinated.The sample pool cap portion of this turning unlatching can be close relative to elasticity
Capping motion, opens sample pool adding mouth or seals.This sample basin lid include overturn connecting portion, can make sample basin lid relative to
Elastic sealing cover for sealed reagent pond part can independently be opened.This test card also includes top cover, top cover with sample basin lid
Relevant position has opening.Top cover opening has for limiting upset connecting portion motion at elastic sealing cover upset connecting portion
Clamping structure.In the present embodiment, the opening of test card top cover correspondence sample pool has clamping structure 101 along BB direction.Work as sample
When basin lid is opened, its upset connecting portion can fix the upset connecting portion in top cover correspondence sample basin lid by clamping structure 101
At opening 103.The upset connecting portion of sample basin lid is less than the width of the opening 103 of top cover, and ensures length L1 and elastic packing
Lid 1 upset connecting portion thickness is close.When sample basin lid is opened, the clamping structure 101 of top cover can be fixed on top cover opening 103
In, facilitate operated by personnel.Clamping structure 101 is the triangular shaped of Jun Shi inclined-plane, two sides in the horizontal direction, vertically
Direction is inclined-plane from down to up, to be easy to open and to cover elastic sealing cover.Top cover 1 is additionally provided with two projections along CC direction
102, protruding 102 two sides are inclined plane shapes.After sample pool cover buckle is closed, protruding 102 can block sample pool, it is ensured that sample pool
Will not unclamp.
Obviously, the above embodiment of the present invention is only for clearly demonstrating example of the present invention, and is not right
The restriction of embodiments of the present invention, for those of ordinary skill in the field, the most also may be used
To make other changes in different forms, cannot all of embodiment be given exhaustive here, every belong to this
What bright technical scheme was extended out obviously changes or changes the row still in protection scope of the present invention.
Claims (10)
1. an in-vitro diagnosis test card adding mouth structure, it is characterised in that this test card includes elastic sealing cover and master successively
Body, described main body includes being formed at the reagent of elastic sealing cover side, sample pool and waste liquid pool, and it is each to be positioned at opposite side
Import connects each reagent and sample pool and the microfluidic channel of outlet waste liquid pool by unpacking mouth respectively;
Described adding mouth structure includes that its inwall forms the cylinder raised up of described sample pool, is positioned at the ring that this cylinder is peripheral
Shape polyrrhea groove, is formed with the through hole connected with described waste liquid pool bottom polyrrhea groove;
Described elastic sealing cover is provided with inside it and seals, with described sample pool polyrrhea groove outer wall, the annular protrusion coordinated;
Described elastic sealing cover is provided with its root and seals the internal projection boss coordinated, the root of this boss with sample pool barrel top
Portion seals with sample pool mates.
2. in-vitro diagnosis test card adding mouth structure as claimed in claim 1, it is characterised in that the ring of described elastic sealing cover
Being provided with one or more spill sump pit inside shape projection, in its structure makes sample pool, discharge flows in described polyrrhea groove.
3. an in-vitro diagnosis test card, it is characterised in that this test card includes elastic sealing cover, main body and bottom, institute successively
Stating main body and include being formed at the reagent of elastic sealing cover side, sample pool and waste liquid pool, described elastic sealing cover is for by each
Reagent seals;
Described sample pool is formed by the inner surface of the cylinder raised up, and this cylinder periphery is provided with annular polyrrhea groove, polyrrhea groove
Bottom is formed with the through hole connected with described waste liquid pool;
This elastic sealing cover includes the sample basin lid relative to the turning unlatching of elastic sealing cover, and this sample basin lid is provided with in it
Side seals, with described sample pool polyrrhea groove outer wall, the annular protrusion coordinated;
Described sample basin lid is provided with its root and seals, with sample pool cylinder inner wall top, the internal projection boss coordinated.
4. in-vitro diagnosis test card as claimed in claim 3, it is characterised in that set inside the annular protrusion of described sample basin lid
Being equipped with one or more spill sump pit, in its structure makes sample pool, discharge flows in described polyrrhea groove.
5. in-vitro diagnosis test card as claimed in claim 3, it is characterised in that described sample basin lid boss designs for undergauge.
6. in-vitro diagnosis test card as claimed in claim 3, it is characterised in that the annular protrusion of described sample basin lid is wedge
Shape.
7. in-vitro diagnosis test card as claimed in claim 3, it is characterised in that this test card farther includes for by described
The fixing top cover on the body of elastic sealing cover, this top cover has opening with described sample basin lid relevant position.
8. in-vitro diagnosis test card as claimed in claim 7, it is characterised in that described elastic sealing cover farther includes upset
Connecting portion, makes described sample basin lid independently can open relative to described elastic sealing cover.
9. in-vitro diagnosis test card as claimed in claim 8, it is characterised in that described top cover opening overturns at elastic sealing cover
There is at connecting portion the clamping structure for limiting upset connecting portion motion.
10. in-vitro diagnosis test card as claimed in claim 7, it is characterised in that described top cover opening farther include for
Compress multiple projections of sample basin lid.
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CN201410637495.9A CN104391127B (en) | 2014-11-11 | 2014-11-11 | A kind of in-vitro diagnosis test card adding mouth structure and in-vitro diagnosis test card |
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CN201410637495.9A CN104391127B (en) | 2014-11-11 | 2014-11-11 | A kind of in-vitro diagnosis test card adding mouth structure and in-vitro diagnosis test card |
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CN104391127B true CN104391127B (en) | 2016-09-14 |
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CN114100710B (en) * | 2021-11-17 | 2022-12-13 | 江苏液滴逻辑生物技术有限公司 | System device, method and application for quantitatively injecting chip detection sample |
CN114100712A (en) * | 2021-11-19 | 2022-03-01 | 江苏液滴逻辑生物技术有限公司 | Hole liquid injection device of micro-fluidic chip, liquid injection method of hole liquid injection device and application of hole liquid injection device |
CN216972496U (en) * | 2022-03-23 | 2022-07-15 | 无锡百泰克生物技术有限公司 | Single-part rapid PCR reaction chip |
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CA2484309C (en) * | 2004-08-31 | 2009-11-03 | James Samsoondar | Sample tab |
US8247191B2 (en) * | 2008-11-13 | 2012-08-21 | Ritzen Kalle | Disposable cassette and method of use for blood analysis on blood analyzer |
CN101520960B (en) * | 2009-03-31 | 2010-09-08 | 四川大学 | Experimental device for in-vitro simulated blood vessel microenvironment |
CN102866257B (en) * | 2011-07-06 | 2013-10-02 | 东莞博识生物科技有限公司 | Micro-fluid sample boat with fluid reservoir and pump chamber |
CN204314316U (en) * | 2014-11-11 | 2015-05-06 | 东莞博识生物科技有限公司 | A kind of in-vitro diagnosis test card adding mouth structure and in-vitro diagnosis test card |
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Address after: Room 702, 7 / F, building 2, Room 802, 8 / F, building 3, No. 15, Jinhui Road, Jinsha community, Kengzi street, Pingshan District, Shenzhen City, Guangdong Province Patentee after: Shenzhen Boshi Diagnostic Technology Co., Ltd Address before: 523808, room 10, building 406, innovation science and Technology Park, Songshan hi tech Industrial Development Zone, Dongguan, Guangdong Patentee before: Dongguan Bozhi Biological Technology Co.,Ltd. |