CN104274619A - Externally-applied pharmaceutical composition for preventing and treating cow mastitis and preparation method of externally-applied pharmaceutical composition - Google Patents
Externally-applied pharmaceutical composition for preventing and treating cow mastitis and preparation method of externally-applied pharmaceutical composition Download PDFInfo
- Publication number
- CN104274619A CN104274619A CN201410581164.8A CN201410581164A CN104274619A CN 104274619 A CN104274619 A CN 104274619A CN 201410581164 A CN201410581164 A CN 201410581164A CN 104274619 A CN104274619 A CN 104274619A
- Authority
- CN
- China
- Prior art keywords
- pharmaceutical composition
- preparation
- cow
- externally
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/33—Cactaceae (Cactus family), e.g. pricklypear or Cereus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/86—Violaceae (Violet family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention discloses an externally-applied pharmaceutical composition for preventing and treating cow mastitis and a preparation method of the externally-applied pharmaceutical composition. The pharmaceutical composition mainly consists of cactus, dandelion and Chinese violet, and is prepared by the following processes: extracting, concentrating, bulking and the like. The product disclosed by the invention can be directly sprayed on cow breasts instead of antibiotics, so as to prevent the cow mastitis; and due to use of the product, the pharmaceutical composition is of great significance in reduction of the pollution to milk caused by the antibiotics and guarantee of the food security.
Description
Technical field
The present invention's " drug regimen of a kind of external control mammitis of cow and preparation method thereof ", main external is sprayed on cow breast, substitute antibiotics and endo-medicine, to prevent and treat the mastitis of milch cow, to ensure that the antibiotic-free of milk remains.
Background technology
The nutritional labeling that milk contains abundant lactoprotein, the needed by human body such as calcareous is wanted.Along with China's economy and social fast development, the demand of people to milk is increasing., high milk production also brings serious burden to milch cow.Show as breast inflammation very general.Mammitis of cow comprises recessive mastitis, dominant mastitis and clinic mastitis three kinds.The cause of disease is many caused by mechanical irritation, pathogenic microorganism immersion and chemicals rationality are damaged.Show as breast and have the inflammation performances such as red, swollen, hot, pain; Lactogenic reduces or stops; Milk changes.People have isolated 150 kinds of pathogenic microorganisms from cow mammary gland tissue, and modal have 23 kinds, wherein 14 kinds, antibacterial, mycoplasma 2 kinds, fungus and 7 kinds, virus.What wherein sickness rate was the highest is staphylococcus aureus, escherichia coli, streptococcus, and mycoplasma, fungus-caused mastitis sickness rate rise year by year in recent years.
Current clinical conventional Therapeutic Method can be divided into three major types, namely with heavy dose of antibiotic carry out whole body therapeutic, antibiotic carries out breast perfusion, or to treat with Chinese herbal medicine.Because antibiotic can remain in milk, have influence on the quality of milk, thus, in recent years, receive the attention of height with herbal control mammitis of cow.
Summary of the invention
The present invention's " drug regimen of a kind of external control mammitis of cow and preparation method thereof ", combines primarily of Radix et Caulis Opuntiae Dillenii, Herba Taraxaci and Herba Violae.Wherein, the proportioning of Radix et Caulis Opuntiae Dillenii, Herba Taraxaci and Herba Violae is Radix et Caulis Opuntiae Dillenii 1 ~ 3 part, Herba Taraxaci 1 ~ 3 part, Herba Violae 1 ~ 3 part.During preparation, by Radix et Caulis Opuntiae Dillenii, Herba Taraxaci and Herba Violae three taste pharmaceutical decocting piece, heating and refluxing extraction 2 times, first time adds the water of 10 ~ 15 times amount, extract 2h, filtered while hot, medicinal residues second time adds the water of 8 ~ 12 times amount, extracts 1 ~ 2h, filter, merging filtrate, being evaporated to relative density is 1.02 ~ 1.10.By this concentrated solution, add the sodium benzoate of its weight 2% ~ 6%, in order to anticorrosion.Finished coffee acid content is not less than 0.05%, loads in container.
Radix et Caulis Opuntiae Dillenii (Classification system: Opuntia stricta) is Cactaceae, the plant of Opuntia.Mildly bitter flavor, cool in nature.Have heat-clearing and toxic substances removing, relaxing muscles and tendons and activating QI and blood in the collateral, dissipating blood stasis for subsidence of swelling, intestinal detoxication, cooling blood and relieving pain, intestine moistening is stopped blooding, benefiting stomach and stopping pain, antitussive.For taste-blindness rate, hemorrhoid, acute dysentery, cough, the treatment of mastitis etc.
Herba Taraxaci (Classification system: Taraxacum mongolicum Hand.-Mazz.) is Compositae Dandelion herbaceos perennial.Bitter but sweet flavor, cold in nature.Function heat-clearing and toxic substances removing, diuresis eliminating stagnation.Be mainly used in treating acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection etc.
Herba Violae (Classification system: Viola philippica) is Violaceae herbaceos perennial.Bitter in the mouth, pungent, cold in nature.Have heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling, and the effect of clearing away heat-damp and promoting diuresis, cures mainly furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.
Three herbal medicines think compatibility, gather the effect of heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation altogether.External is directly sprayed onto on the breast of milch cow, to control mammitis of cow, has good effect.
Detailed description of the invention
Embodiment 1
Get Radix et Caulis Opuntiae Dillenii decoction pieces 1 part, Herba Taraxaci decoction pieces 2 parts and Herba Violae decoction pieces 1 part, add the water of 12 times amount, heating and refluxing extraction 2h, filtered while hot.Medicinal residues add the water of 10 times amount, reflux, extract, 1.5h, filtered while hot.Merging filtrate, being evaporated to relative density is 1.02, adds the sodium benzoate of solution weight 5%, bottles.
Embodiment 2
Get Radix et Caulis Opuntiae Dillenii decoction pieces 2 parts, Herba Taraxaci decoction pieces 1 part and Herba Violae decoction pieces 1 part, add the water of 15 times amount, heating and refluxing extraction 2.5h, filtered while hot.Medicinal residues add the water of 8 times amount, reflux, extract, 2h, filtered while hot.Merging filtrate, being evaporated to relative density is 1.05, adds the sodium benzoate of solution weight 6%, bottles.
Embodiment 3
Get Radix et Caulis Opuntiae Dillenii decoction pieces 1 part, Herba Taraxaci decoction pieces 1 part and Herba Violae decoction pieces 2 parts, add the water of 10 times amount, heating and refluxing extraction 1.5h, filtered while hot.Medicinal residues add the water of 12 times amount, reflux, extract, 1h, filtered while hot.Merging filtrate, being evaporated to relative density is 1.04, adds the sodium benzoate of solution weight 3%, bottles.
Claims (4)
1. an external prevents and treats drug regimen of mammitis of cow and preparation method thereof, it is characterized in that: combine primarily of Radix et Caulis Opuntiae Dillenii, Herba Taraxaci and Herba Violae.
2. a kind of external according to claim 1 prevents and treats drug regimen of mammitis of cow and preparation method thereof, it is characterized in that: the proportioning of Radix et Caulis Opuntiae Dillenii, Herba Taraxaci and Herba Violae is Radix et Caulis Opuntiae Dillenii 1 ~ 3 part, Herba Taraxaci 1 ~ 3 part, Herba Violae 1 ~ 3 part.
3. a kind of external according to claim 1 prevents and treats drug regimen of mammitis of cow and preparation method thereof, it is characterized in that: by Radix et Caulis Opuntiae Dillenii, Herba Taraxaci and Herba Violae three taste pharmaceutical decocting piece, heating and refluxing extraction 2 times, first time adds the water of 10 ~ 15 times amount, extract 1.5 ~ 2.5h, filtered while hot, medicinal residues second time adds the water of 8 ~ 12 times amount, extracts 1 ~ 2h, filter, merging filtrate, being evaporated to relative density is 1.02 ~ 1.10, adds the sodium benzoate of solution weight 2 ~ 5% as antiseptic.
4. drug regimen and preparation method thereof of a kind of external control mammitis of cow according to claim 1, is characterized in that: by concentrated solution according to claim 3, detects its caffeic acid content and be not less than 0.05%, to be filled in container to obtain finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410581164.8A CN104274619A (en) | 2014-10-27 | 2014-10-27 | Externally-applied pharmaceutical composition for preventing and treating cow mastitis and preparation method of externally-applied pharmaceutical composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410581164.8A CN104274619A (en) | 2014-10-27 | 2014-10-27 | Externally-applied pharmaceutical composition for preventing and treating cow mastitis and preparation method of externally-applied pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104274619A true CN104274619A (en) | 2015-01-14 |
Family
ID=52250280
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410581164.8A Pending CN104274619A (en) | 2014-10-27 | 2014-10-27 | Externally-applied pharmaceutical composition for preventing and treating cow mastitis and preparation method of externally-applied pharmaceutical composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104274619A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104367715A (en) * | 2014-12-03 | 2015-02-25 | 徐自升 | Pure Chinese medicine compound for prevention and treatment of mastitis of dairy cows and preparation method thereof |
| CN106176955A (en) * | 2016-07-22 | 2016-12-07 | 太仓市爱农奶牛专业合作社 | A kind of antiinflammatory treating mammitis of cow and preparation method thereof |
| CN106237119A (en) * | 2016-08-18 | 2016-12-21 | 刘娟 | A kind of prevention and the medicine for the treatment of Mammitis of cattle |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101957345A (en) * | 2010-03-05 | 2011-01-26 | 浙江京新药业股份有限公司 | Method for detecting active ingredients in American cockroach extract |
| CN102716168A (en) * | 2012-06-28 | 2012-10-10 | 齐鲁动物保健品有限公司 | Rifaximin-containing preparation for preventing and treating dairy cow mastitis during dry period and method for preparing rifaximin-containing preparation |
| CN102885855A (en) * | 2012-11-10 | 2013-01-23 | 昆明赛诺制药有限公司 | Production method for preparing medicine for treating peptic ulcer by periplaneta americana extract |
| CN103083393A (en) * | 2013-01-24 | 2013-05-08 | 山西华诚睿光生物科技有限公司 | Disinfect and sterile spray for preventing bouine mastitis and preparation method of spray |
-
2014
- 2014-10-27 CN CN201410581164.8A patent/CN104274619A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101957345A (en) * | 2010-03-05 | 2011-01-26 | 浙江京新药业股份有限公司 | Method for detecting active ingredients in American cockroach extract |
| CN102716168A (en) * | 2012-06-28 | 2012-10-10 | 齐鲁动物保健品有限公司 | Rifaximin-containing preparation for preventing and treating dairy cow mastitis during dry period and method for preparing rifaximin-containing preparation |
| CN102885855A (en) * | 2012-11-10 | 2013-01-23 | 昆明赛诺制药有限公司 | Production method for preparing medicine for treating peptic ulcer by periplaneta americana extract |
| CN103083393A (en) * | 2013-01-24 | 2013-05-08 | 山西华诚睿光生物科技有限公司 | Disinfect and sterile spray for preventing bouine mastitis and preparation method of spray |
Non-Patent Citations (2)
| Title |
|---|
| 宋士斌: "奶牛乳房炎的中药疗法", 《农村实用科技信息》 * |
| 陶大勇: "《畜禽常见病诊断及防治实用技术》", 30 April 2006 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104367715A (en) * | 2014-12-03 | 2015-02-25 | 徐自升 | Pure Chinese medicine compound for prevention and treatment of mastitis of dairy cows and preparation method thereof |
| CN106176955A (en) * | 2016-07-22 | 2016-12-07 | 太仓市爱农奶牛专业合作社 | A kind of antiinflammatory treating mammitis of cow and preparation method thereof |
| CN106237119A (en) * | 2016-08-18 | 2016-12-21 | 刘娟 | A kind of prevention and the medicine for the treatment of Mammitis of cattle |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104274619A (en) | Externally-applied pharmaceutical composition for preventing and treating cow mastitis and preparation method of externally-applied pharmaceutical composition | |
| CN103301251B (en) | Traditional Chinese medicine composition for preventing and cow treating mastitis | |
| CN104367746A (en) | Compound traditional Chinese medicine perfusion agent used for treating endometritis of dairy cow and preparation method of compound traditional Chinese medicine perfusion agent | |
| CN103520649B (en) | The Chinese medicine for the treatment of facial neuritis | |
| CN101612335A (en) | Be used to Chinese medicine composition of preventing and treating mammitis of cow and preparation method thereof | |
| CN102274353B (en) | Traditional Chinese preparation for treating ulcers | |
| CN107412684A (en) | A kind of stone frog tadpole inflammation medication and its preparation technology | |
| CN111494574A (en) | Traditional Chinese medicine composition for treating cellulitis | |
| CN103405503B (en) | A kind of compound Chinese medicinal preparation and preparation method for the treatment of acute mastitis | |
| CN104367715A (en) | Pure Chinese medicine compound for prevention and treatment of mastitis of dairy cows and preparation method thereof | |
| CN105287785A (en) | Traditional Chinese medicine for treating hyperthermia toxin symptoms of livestock and poultry and preparation method of traditional Chinese medicine | |
| CN104873598A (en) | Chinese medicinal composition for treating infantile hand-foot-mouth disease | |
| CN105125639A (en) | Traditional Chinese medicine composition for preventing and treating mastitis of dairy cattle | |
| CN103285079B (en) | Preparation process of perfusion agent for treating dairy cow mastitis | |
| CN107951972A (en) | Apply medicinal lotion or ointment outside a kind of Chinese traditional medicine composition for treating mastitis for milk cows thing and preparation method thereof | |
| CN102793869A (en) | Traditional Chinese medicine composition for controlling porcine viral diseases and preparation method thereof | |
| CN106266284A (en) | A kind of Chinese medicine for oral administration treating mammitis of cow | |
| CN110604806A (en) | Traditional Chinese medicine preparation for treating infantile cough and preparation method thereof | |
| CN104971210A (en) | External lotion for treating tinea pedis and preparation method thereof | |
| CN104208597A (en) | Chinese medicinal formula for treating kidney stone | |
| CN109419929A (en) | One group for treating the Chinese medicine of acute bacillary dysentery | |
| CN103805452A (en) | Wild grape wine with function of strengthening heart and brains and production method | |
| CN115364167A (en) | Traditional Chinese medicine oral liquid for treating cow mastitis and preparation method thereof | |
| CN111419921A (en) | Traditional Chinese medicine composition for treating acne, carbuncle and furuncle | |
| CN116509969A (en) | Traditional Chinese medicine composition for treating cow clinical type mastitis and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150114 |