CN104248478A - Multifunctional device for simulating extracorporeal cardiac functions and testing valve performance - Google Patents
Multifunctional device for simulating extracorporeal cardiac functions and testing valve performance Download PDFInfo
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- CN104248478A CN104248478A CN201410428748.1A CN201410428748A CN104248478A CN 104248478 A CN104248478 A CN 104248478A CN 201410428748 A CN201410428748 A CN 201410428748A CN 104248478 A CN104248478 A CN 104248478A
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- runner
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- electric motors
- linear electric
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2472—Devices for testing
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- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a multifunctional device for simulating extracorporeal cardiac functions and testing valve performance. The multifunctional device comprises a runner, a linear motor, damping devices and complying devices. The runner is a closed loop provided with a plurality of openings. Pressure sensors are arranged in the runner. A piston is mounted on a spindle of the linear motor in a sleeved manner. The linear motor is mounted above the runner. The piston is arranged in the runner. Valve fixing devices are respectively arranged in the runner at two ends of the linear motor. The complying devices and the damping devices are arranged a complementary runner formed by the linear motor and the two valve fixing devices. The multifunctional device is simple in structure and novel in design; through change of the connection mode of an external runner, functions such as heart valve prosthesis endurance performance testing, heart valve prosthesis pulsating-flow performance testing, left-heart auxiliary pump performance testing, intervention valve simulation use testing and pulsating pressure generating are integrated, so that convenience is brought to users to a great extent, and equipment purchase cost is reduced.
Description
Technical field
The present invention relates to a kind of test set of medical instruments field, more specifically relate to a kind of multipurpose test system for the simulation of Multifunctional external cardiac function.
Background technology
Cardiovascular disease causes in world wide the main cause disabled with premature death, add up according to world Heart Federation, in worldwide often in dead three people, cardiovascular disorder with regard to there being the cause of the death of a people, and the mortality rate of cardiovascular disease is far above the other diseases comprising cancer, acquired immune deficiency syndrome (AIDS), become " number one killer " that threaten human health.For cardiovascular disease, at present mainly through Drug therapy or adopt corresponding cardiac vascular medical apparatus to carry out external auxiliary treatment or carry out transplanting in body.Adopt corresponding cardiac vascular medical apparatus to carry out before auxiliary treatment or cardiac vascular medical apparatus carry out implant surgery, simulation test must be carried out to guarantee that it is safe and effective to its property indices in vitro.And cardiac vascular medical apparatus is when testing in vitro, the device of corresponding test need be had to provide necessary test environment and condition for it.
Chinese patent notification number is the simulated circulation test system that CN100348279C discloses a kind of artificial heart, this system is made up of four test chambers and relevant connection stream, testing equipment and stream device, by adopting self-adaptive damping valve and corresponding connectivity structure, in conjunction with the setting of chamber compliance and manual orifice valve structure, characterize the dynamic response characteristic of human body artery blood vessel, make system can carry out adjustment test according to the physiological parameter of initial selected.This system bulk is relatively little, and test is comparatively flexible, but its function singleness, can only the performance of the arterial vascular dynamic response characteristic of testing human and artificial heart dynamical system.But cardiac vascular medical apparatus needs the index of test a lot, as the performance etc. that the simulation of blood flowing characteristic, stability and intervention lobe uses.If when cardiac vascular medical apparatus often carries out a test, all need again to change test set, not only waste time and energy, and substantially increase the cost of test.
Summary of the invention
For above-mentioned deficiency, a kind of structure external cardiac function that is simple, that integrate multiple test function is the object of the present invention is to provide to simulate and valve performance testing device.
The present invention is achieved by the following technical solutions:
A kind of Multifunctional external cardiac function simulation and valve performance testing device, described device comprises runner, linear electric motors, compliant device and damping unit, described runner is the closed-loop path being provided with multiple opening, pressure transducer is provided with in described runner, the main shaft of described linear electric motors is set with piston, described linear electric motors are installed on above runner, and described piston is arranged in runner; Valve fixture is respectively arranged with: valve fixture one and valve fixture two in the runner at described linear electric motors two ends, the complementary runner that described valve fixture one, linear electric motors and valve fixture two are formed is provided with compliant device and damping unit, and described compliant device, damping unit are connected with runner.
As this technical scheme further, described pressure transducer at least arranges two: pressure transducer one and pressure transducer two, described pressure transducer one is arranged on the runner between linear electric motors and valve fixture one, and described pressure transducer two is arranged in the runner between valve fixture one and compliant device.
As this technical scheme further, described pressure transducer one is connected with computer system by control chamber with pressure transducer two.
As this technical scheme further, described runner is at least provided with three openings, described opening is separately positioned on the runner on the runner on the runner between linear electric motors and valve fixture two, between valve fixture one and compliant device and between compliant device and valve fixture two.
As this technical scheme further, be also provided with heater and temperature sensor in described runner, further, described heater and temperature sensor are all connected with computer system by controller.
As this technical scheme further, described runner is provided with three cover compliant device and two cover damping units.
As this technical scheme further, described linear electric motors are connected with computer system by controller.
As this technical scheme further, the external cardiac function simulation of described one and device for testing endurance are used for Cardiac valve prosthesis durability test, the performance test of Cardiac valve prosthesis pulsating flow, left ventricular assist pump performance test, get involved lobe simulation use test and use as pulsation pressure generator.
Beneficial effect: structure of the present invention is simple, novel, deft design, Cardiac valve prosthesis durability test function, the performance test of Cardiac valve prosthesis pulsating flow, left ventricular assist pump performance test, the simulation of intervention lobe are used test function and are integrated in one as pulsation pressure generator function by the connection changing runner by this device, reduce the acquisition cost of equipment to a great extent, simplify operation, and due to reasonable in design, the integrated cost of later stage working service is also lower; In addition, this structural volume is little, is convenient to mobile and transport, expands its scope of application and also reduce cost of transportation.
accompanying drawing illustrates:
Fig. 1 is the axonometric chart of the present embodiment.
Fig. 2 is the top view of the present embodiment.
Fig. 3 is structural representation when carrying out left ventricular assist pump performance test.
Fig. 4 carries out getting involved the structural representation that lobe simulation uses test.
detailed description of the invention:
Below in conjunction with accompanying drawing and embodiment, the invention will be further described, but the protection domain of invention not limit by embodiment.
See Fig. 1, a kind of Multifunctional external cardiac function simulation and valve performance testing device, mainly comprise runner 1, linear electric motors 2, damping unit 3 and compliant device 4.Runner 1 is the close passage formed by four placed in series, and the two ends of every bar passage all seal with lucite cover plate and O type circle.In order to protect runner 1, be arranged at by runner 1 in the body 1a of a cuboid, simultaneously for the ease of observation test situation, cuboid body 1a is made up of transparent lucite.
Runner 1 is provided with linear electric motors 2, the main shaft of linear electric motors 2 is set with a piston 5, piston 5 probes into and is arranged in runner 1.Linear electric motors 2 drive piston 5 to move up and down simulation the beating, for test set provides pressure and power of human heart.
See Fig. 2, in the runner 1 at linear electric motors 2 two ends, be separately installed with valve fixture 1 and valve fixture 27.For the ease of observing the open and-shut mode of valve, can on body 1a, on the position corresponding with valve fixture 1 and valve fixture 27, offer a transparent observation window 8 respectively.Runner 1 between linear electric motors 2 and valve fixture 1 is provided with a pressure transducer 1, the probe of pressure transducer 1 probes into and is arranged in runner 1, the other end of pressure transducer 1 is connected with control chamber by cable, and controller transfers data to computer system again.At valve fixture 1 right-hand member, (following left and right, clockwise and counterclockwise description is all standard with Fig. 2, be not limited to the restriction to structure of the present invention) runner 1 on pressure transducer 2 10 is installed, the mounting means of pressure transducer 2 10 and pressure transducer are together, it probes into and is arranged in runner 1, the other end of pressure transducer 2 10 is connected with control chamber by cable, control chamber transfers data to computer system again, pressure transducer 9 and 10 in this device respectively analogue measurement be ventricular pressure and aortic pressure.Clockwise, the runner between valve fixture 1 and valve fixture 27 is provided with successively the liquid capacitance device 3c of compliant device one 3a, damping unit one 4a, compliant device two 3b, damping unit two 4b and damping unit three.Compliant device one 3a, compliant device two 3b and liquid capacitance device 3c are connected with runner 1.Damping unit one 4a and damping unit two 4b is then arranged in runner 1.The setting of compliant device one 3a is to regulate aortal compliance, and compliant device two 3b is for regulating peripheral vascular compliance, and liquid capacitance device 3c complies with characteristic in order to what regulate left atrium.The effect of damping unit one 4a regulates aortal damping, and the setting of damping unit two 4b is then for regulating peripheral vascular damping.
See Fig. 2, in order to regulate and monitor the temperature of liquid in runner 1, one temperature sensor 12 is set in the runner 1 between film lobe fixture 27 and compliant device three 3c, and a heating rod 11 is installed in runner 1 near compliant device two 3b, the probe of temperature sensor 12 is arranged in runner 1, the other end of temperature sensor 12 is connected with control chamber by cable, and control chamber transfers data to computer system again; The installation connected mode of heating rod 11 is identical with temperature sensor 12.
When carrying out Cardiac valve prosthesis pulsatile flow test, film lobe fixture 1 in fig. 2 and film lobe fixture 27 place load onto tested Cardiac valve prosthesis, and in compliant device 3, add appropriate test fluid, damping adjusting device 4 is to suitable impedance simultaneously.
Start linear electric motors 2 and control chamber, pressure transducer 1 and pressure transducer 2 10 enter duty, for testing aortal systolic pressure and diastolic pressure, heating rod 11 in runner 1 is for heating test fluid, temperature sensor 12 is for controlling the temperature of test fluid, and the combined effect of the two makes the operating temperature of test fluid maintain 37 DEG C ± 0.1 DEG C always.During work, linear electric motors 2 are moved up and down and by piston 5, pressure are passed to the test fluid of this section, test fluid flows through pressure transducer 1, film lobe fixture 1, pressure transducer 2 10, compliant device 3, damping unit 4 and film lobe fixture 27 clockwise, finally be back to original point, whole process simulation human heart is beated blood supply, can be recorded the pulsating flow performance parameter of Cardiac valve prosthesis by the data of display on pressure transducer one and pressure transducer two.
When carrying out the test of Cardiac valve prosthesis endurance quality, film lobe fixture 1 in Fig. 2 is removed, be fixed on by tested Cardiac valve prosthesis in film lobe fixture 27, wherein the installation direction of Cardiac valve prosthesis is contrary with installation direction when carrying out pulsatile flow test; Then in runner 1, passed into the test fluid of aequum by compliant device one 3a, damping adjusting device one 4a and damping unit 4b is to suitable impedance simultaneously.
Open linear electric motors 2 and control chamber, the pressure and temperature of whole test macro is controlled by pressure transducer 9 and 10, heating rod 11 and temperature sensor 12 respectively, and heating rod 11 and temperature sensor 12 combined effect make the operating temperature of test fluid maintain 37 DEG C all the time.Start linear electric motors 2, linear electric motors 2 move up and down and directly act in this section of test fluid by piston 5 by power, and because Cardiac valve prosthesis is one-way flow, test fluid rolling action power is transmitted counterclockwise in runner, is finally back to initial point.Test fluid is in the process of flowing, and active force acts on the artificial valve on film lobe holder 27, until artificial heart film lobe destroys the endurance quality can measuring Cardiac valve prosthesis.
During left ventricular assist pump performance test, see Fig. 3, runner 1 between compliant device one 3a and damping unit one 4a is carried out shutoff, an external left ventricular assist pump on this device, left ventricular assist pump is connected with this device by pipeline, concrete connected mode is: the end cap opening linear electric motors 2 side passway A, special joint is equipped with at A place, passway, the effect of special joint is conveniently connecting pipe, joint external pipe on the A of this passway, pipeline is connected in series with a left ventricular assist pump, left ventricular assist pump is connected with the passway C of damping unit one 4a side with the passway B on the right side of valve fixture 1 respectively by pipeline again.Wherein special joint is also all equipped with in passway B, C place, passway, facilitates the connection of passway B and passway C and pipeline.Appropriate test fluid is injected to this device by compliant device one 3a.
Open linear electric motors 2 and control chamber, control chamber controlled pressure sensor 1 and pressure transducer 2 10 carry out duty, heating rod 11 in runner 1 and temperature sensor 12 also enter duty under the effect of controller, heating rod 11 is for heating test fluid, temperature sensor 12 then controls the temperature of test fluid, and the combined effect of the two makes the operating temperature of test fluid maintain 37 DEG C always.During work, linear electric motors 2 are moved up and down and by piston, power are passed to the test fluid of this section, and test fluid flows simultaneously in external pipeline and runner, and a part of test fluid through piping, left ventricular assist pump, then enters pipeline; Another part test fluid flows in runner, passway B is arrived through valve fixture 1, last two parts test fluid is converged at B place, passway, eventually enters from passway C, is back to original point via damping unit two 4b, liquid capacitance device 3c and valve fixture 27.This test is by external left ventricular assist pump, thus the parameters of test left ventricular assist pump under different pressures, flow and heart rate.
When carrying out the simulation of intervention lobe and using test, see Fig. 4, an external aorta silica gel model between the passway C of the passway B on the right side of film lobe fixture 1 and compliant device two 3b side, runner 1 between compliant device one 3a and damping unit one 4a is carried out shutoff simultaneously, then in whole device, inject test fluid to compliant device one 3a.The conveniently connection of passway B and passway C and pipeline, can load onto special joint at passway B and C place, passway.
Open linear electric motors 2 and control chamber, duty is carried out in control chamber controlled pressure sensor 1, pressure transducer 2 10, heating rod 11 and temperature sensor 12, and the heating rod 11 in runner 1 and temperature sensor 12 combined effect make the operating temperature of test fluid maintain 37 DEG C always.
Doctor can sham operated on-the-spot, intend release at aorta silica gel model patrix and get involved lobe, thus the accuracy of exercise operation release.In addition, aorta silica gel model also can change arteria coronaria model or the cardiovascular products such as support, conduit into.
When as pulsation pressure generator, the runner 1 of valve fixture 1 and valve fixture 27 both sides is carried out shutoff, open a passway A of linear electric motors 2 side, connect the device needing to provide pressure, again by another passway of linear electric motors 2 side, in the runner between the valve fixture 1 and valve fixture 27 of this section of runner 1(linear electric motors 2 correspondence) inject test fluid.Open linear electric motors 2, linear electric motors 2 move up and down produce pressure pass to test fluid by piston 5, test fluid is passed to required device again.
Claims (9)
1. a Multifunctional external cardiac function simulation and valve performance testing device, it is characterized in that: described device comprises runner, linear electric motors, compliant device and damping unit, described runner is the closed-loop path being provided with multiple opening, pressure transducer is provided with in described runner, the main shaft of described linear electric motors is set with piston, described linear electric motors are installed on above runner, and described piston is arranged in runner; Valve fixture is respectively arranged with: valve fixture one and valve fixture two in the runner at described linear electric motors two ends, the complementary runner that described valve fixture one, linear electric motors and valve fixture two are formed is provided with compliant device and damping unit, and described compliant device, damping unit are connected with runner.
2. a kind of Multifunctional external cardiac function simulation according to claim 1 and valve performance testing device, it is characterized in that: described pressure transducer at least arranges two: pressure transducer one and pressure transducer two, described pressure transducer one is arranged on the runner between linear electric motors and valve fixture one, and described pressure transducer two is arranged in the runner between valve fixture one and compliant device.
3. a kind of Multifunctional external cardiac function simulation according to claim 1 and 2 and valve performance testing device, is characterized in that: described pressure transducer one is connected with computer system by control chamber with pressure transducer two.
4. a kind of Multifunctional external cardiac function simulation according to claim 1 and valve performance testing device, it is characterized in that: described runner is at least provided with three openings, described opening is separately positioned on the runner on the runner on the runner between linear electric motors and valve fixture two, between valve fixture one and compliant device and between compliant device and valve fixture two.
5. a kind of Multifunctional external cardiac function simulation according to claim 1 and valve performance testing device, is characterized in that: be also provided with heater and temperature sensor in described runner.
6. a kind of Multifunctional external cardiac function simulation according to claim 5 and valve performance testing device, is characterized in that: described heater and temperature sensor are all connected with computer system by control chamber.
7. a kind of Multifunctional external cardiac function simulation according to claim 1 and valve performance testing device, is characterized in that: described runner is provided with three cover compliant device and two cover damping units.
8. a kind of Multifunctional external cardiac function simulation according to claim 1 and valve performance testing device, is characterized in that: described linear electric motors are connected with computer system by control chamber.
9. a kind of Multifunctional external cardiac function simulation according to claim 1-8 any one and valve performance testing device are used for Cardiac valve prosthesis durability test, the performance test of Cardiac valve prosthesis pulsating flow, left ventricular assist pump performance test, get involved lobe simulation use test and use as pulsation pressure generator.
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| CN201410428748.1A CN104248478A (en) | 2014-08-28 | 2014-08-28 | Multifunctional device for simulating extracorporeal cardiac functions and testing valve performance |
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104966452A (en) * | 2015-07-16 | 2015-10-07 | 苏州心伴测试科技有限公司 | Multifunctional modularization blood flow dynamics analog device |
| CN105784406A (en) * | 2016-05-12 | 2016-07-20 | 北京精密机电控制设备研究所 | Extracorporal integrated test system for ventricular assist devices |
| CN107773328A (en) * | 2016-08-24 | 2018-03-09 | 上海市同济医院 | Testing external performance system and its method of testing through conduit mitral valve support |
| CN107974406A (en) * | 2017-12-01 | 2018-05-01 | 西安交通大学 | Intravascular stent is degraded and fatigue property test bioreactor and its test method |
| CN108593489A (en) * | 2018-07-12 | 2018-09-28 | 中北大学 | 3D printing magnesium alloy materials degradation system safety testing device and application |
| CN109172047A (en) * | 2018-09-18 | 2019-01-11 | 上海工程技术大学 | Heart valve prosthesis function test system |
| CN109900885A (en) * | 2019-02-13 | 2019-06-18 | 清华大学 | Interventional medical equipment and medical material test macro and corresponding experimental method |
| CN110269727A (en) * | 2019-06-27 | 2019-09-24 | 湖北雄志医疗设备科技有限公司 | A kind of bionical test simulation dynamic device of Artificial Intervention mechanical heart valve |
| CN110269726A (en) * | 2019-06-27 | 2019-09-24 | 湖北雄志医疗设备科技有限公司 | A kind of mechanical heart valve analoging detecting device |
| CN110538003A (en) * | 2019-08-30 | 2019-12-06 | 宁波健世生物科技有限公司 | Heart valve opening and closing detector |
| CN111437069A (en) * | 2020-04-26 | 2020-07-24 | 科凯(南通)生命科学有限公司 | Heart valve flow performance detection device |
| US10898329B2 (en) | 2019-01-25 | 2021-01-26 | Edwards Lifesciences Corporation | Testing apparatus for prosthetic device |
| CN112557081A (en) * | 2020-12-14 | 2021-03-26 | 深圳核心医疗科技有限公司 | Test system |
| CN113670595A (en) * | 2021-08-25 | 2021-11-19 | 天津市医疗器械质量监督检验中心 | Method for testing fatigue limit of tissue clamping device |
| CN113706987A (en) * | 2021-09-28 | 2021-11-26 | 大连理工大学 | Physical platform for simulating typical pulmonary hypertension generation and development process |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104966452A (en) * | 2015-07-16 | 2015-10-07 | 苏州心伴测试科技有限公司 | Multifunctional modularization blood flow dynamics analog device |
| CN105784406A (en) * | 2016-05-12 | 2016-07-20 | 北京精密机电控制设备研究所 | Extracorporal integrated test system for ventricular assist devices |
| CN107773328A (en) * | 2016-08-24 | 2018-03-09 | 上海市同济医院 | Testing external performance system and its method of testing through conduit mitral valve support |
| CN107773328B (en) * | 2016-08-24 | 2023-10-03 | 上海市同济医院 | In-vitro performance test system and method for transcatheter mitral valve stent |
| CN107974406A (en) * | 2017-12-01 | 2018-05-01 | 西安交通大学 | Intravascular stent is degraded and fatigue property test bioreactor and its test method |
| CN108593489A (en) * | 2018-07-12 | 2018-09-28 | 中北大学 | 3D printing magnesium alloy materials degradation system safety testing device and application |
| CN108593489B (en) * | 2018-07-12 | 2020-11-06 | 中北大学 | 3D printing magnesium alloy material degradability testing device and application |
| CN109172047A (en) * | 2018-09-18 | 2019-01-11 | 上海工程技术大学 | Heart valve prosthesis function test system |
| CN109172047B (en) * | 2018-09-18 | 2023-09-15 | 上海工程技术大学 | Prosthetic heart valve function test system |
| US10898329B2 (en) | 2019-01-25 | 2021-01-26 | Edwards Lifesciences Corporation | Testing apparatus for prosthetic device |
| CN109900885B (en) * | 2019-02-13 | 2020-05-19 | 清华大学 | Interventional medical instrument and medical material testing system and corresponding experimental method |
| CN109900885A (en) * | 2019-02-13 | 2019-06-18 | 清华大学 | Interventional medical equipment and medical material test macro and corresponding experimental method |
| CN110269726A (en) * | 2019-06-27 | 2019-09-24 | 湖北雄志医疗设备科技有限公司 | A kind of mechanical heart valve analoging detecting device |
| CN110269727A (en) * | 2019-06-27 | 2019-09-24 | 湖北雄志医疗设备科技有限公司 | A kind of bionical test simulation dynamic device of Artificial Intervention mechanical heart valve |
| CN110538003A (en) * | 2019-08-30 | 2019-12-06 | 宁波健世生物科技有限公司 | Heart valve opening and closing detector |
| CN111437069A (en) * | 2020-04-26 | 2020-07-24 | 科凯(南通)生命科学有限公司 | Heart valve flow performance detection device |
| CN112557081A (en) * | 2020-12-14 | 2021-03-26 | 深圳核心医疗科技有限公司 | Test system |
| CN112557081B (en) * | 2020-12-14 | 2022-10-28 | 深圳核心医疗科技有限公司 | Test system |
| CN113670595A (en) * | 2021-08-25 | 2021-11-19 | 天津市医疗器械质量监督检验中心 | Method for testing fatigue limit of tissue clamping device |
| CN113706987A (en) * | 2021-09-28 | 2021-11-26 | 大连理工大学 | Physical platform for simulating typical pulmonary hypertension generation and development process |
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