CN104212707B - A kind of disposable intestinal contents target component extraction element - Google Patents

A kind of disposable intestinal contents target component extraction element Download PDF

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Publication number
CN104212707B
CN104212707B CN201410484176.9A CN201410484176A CN104212707B CN 104212707 B CN104212707 B CN 104212707B CN 201410484176 A CN201410484176 A CN 201410484176A CN 104212707 B CN104212707 B CN 104212707B
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China
Prior art keywords
filtering net
target component
extraction
roll shaft
intestinal contents
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Expired - Fee Related
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CN201410484176.9A
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CN104212707A (en
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李莉
王玉洁
国霞
苗翠
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Qingdao Municipal Hospital
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Qingdao Municipal Hospital
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02Separating microorganisms from the culture medium; Concentration of biomass

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a kind of disposable intestinal contents target component extraction element, comprise extraction tube, extraction tube comprises only upper end open and can the filtering net that is connected with the inner wall sealing of body with some levels of the body of hot-seal, body also comprises and is arranged on fluid injection end on tube wall and liquid pumping side, fluid injection end is between upper end open and the filtering net of the first step, liquid pumping side is between two-stage neighboring filtering net, from top to bottom aperture is in the trend reduced step by step for filtering net, and body is soft polymer material.Beneficial effect of the present invention is: structure is simple, easy to operate, for caprophyl provides a kind of oxygen-free environment, can ensure the integrity of caprophyl, improves the effect of transplanting caprophyl disease therapy.

Description

A kind of disposable intestinal contents target component extraction element
Technical field
The present invention relates to a kind of medical collection device, particularly relate to a kind of disposable intestinal contents target component extraction element.
Background technology
Human gastrointestinal tract content has that swill, flora, parasitic ovum etc. are multiple row composition, there is the body fluid components that intestinal secretion generates, have because a variety of causes enters foreign matter in enteron aisle and liquid, also have by Endoscopic removal but the tumor tissues in small, broken bits of not easily directly taking-up.In clinical and research process, differentiate and obtain the composition of these objects, only have rely on effective apparatus auxiliary separating from.Flora in normal human's enteron aisle to be considered in human body a special organ, and ight soil is transplanted and is considered to a kind of special organ transplantation.The bacterium of enteron aisle is about 1000 to 1050 kinds, and the current mankind to the function of wherein Most bacterial, and according to what mechanism organically work between different bacterium, all it be unclear that.Recently, modern medicine has more and more recognized the vital role of intestinal bacteria in human body, will maintain or rebuild the critical treatment means of human intestinal normal microflora as various diseases.Conventional probiotic bacterium medicine and food, just by one or more bacteriums of enteron aisle, through external special cultivation, are then packed according to certain amount.But, because to include the bacteria's numbers and species of human intestinal in all very limited, so its therapeutic value is also very limited.Recent years, caprophyl is transplanted and is paid attention to gradually, especially for the disease that the infection that the pharmacological agenies such as common antibiotics are invalid is relevant, its therapeutic value seems and particularly payes attention to, especially for the disease that the infection that the pharmacological agenies such as common antibiotics are invalid is relevant, its therapeutic value seems particularly important, such as treats antibiotic-associated diarrhea, intractable inflammatory enteritis, Treatment of Refractory Irritable Bowel Syndrome, immunity relevant intractable diarrhoea, obesity, food anaphylaxis, dysthymia disorders bowel symptoms, fatty liver etc.
Scientific development so far, although had a few studies by intestines mirror, gastroscope nasogastric tube, jejunum pipe, stool suspension or caprophyl suspension are transported in gi tract by capsules etc., realize caprophyl to transplant, but, all there is such problem in the extracting method before caprophyl transplanting, owing to being substantially in oxygen-free environment in body enteron aisle, namely most caprophyl belongs to anaerobic bacterium, existing extraction equipment is not all for caprophyl provides a kind of oxygen-free environment, if the patent No. is CN201310051614, patent name is: a kind of medical cavity content target component reclaims apparatus, it is injected by malleation, vacuum suction, the modes of action such as gravity are fecal suspension circulation, filtration etc. provides required strength, such extraction element cannot provide oxygen-free environment for caprophyl, cause most of caprophyl dead, be difficult to the high quality ensureing caprophyl sample, reduce the result for the treatment of of caprophyl to some disease.
Summary of the invention
The object of the present invention is to provide a kind of structure simple, can ensure that flora is in oxygen-free environment and improves the disposable intestinal contents target component extraction element of caprophyl specimen quality.
The present invention is realized by following measure: a kind of disposable intestinal contents target component extraction element, comprise extraction tube, described extraction tube comprises only upper end open and the filtering net that is connected with the inner wall sealing of described body with some levels of the body that can seal, described body also comprises and is arranged on fluid injection end on described tube wall and liquid pumping side, described fluid injection end is between upper end open and the described filtering net of the first step, described liquid pumping side is between two adjacent described filtering nets, described filtering net from top to bottom aperture is the trend reduced step by step, described body is soft polymer material.
The quantity of described filtering net is preferably 5-30; Interval is had between filtering net described in adjacent two-stage.
Described sealing can be hot-seal, also directly can be rolled by opening and clamp, ensure that opening seals.
The material of described body is silica gel, soft rubber, PVC or soft plastics, and one-body molded.
The aperture of described filtering net is 0.0004-5.00mm.
Also comprise with described extraction tube with the use of extraction press from both sides, described extraction folder comprises two parallel extrusion rolls, described extrusion roll comprises roll shaft and can along the roller of described roll shaft radial rotary, the two ends of described roll shaft are symmetrically arranged with through hole, and two described extrusion rolls are connected with ears nut by the lead screw through described through hole.
The screw terminal of described lead screw is yi word pattern, is provided with yi word pattern limited impression with on roll shaft described in described screw terminal correspondence position.
Beneficial effect of the present invention is: structure is simple, easy to operate, for caprophyl provides a kind of oxygen-free environment, can ensure the integrity of caprophyl, improves the effect of transplanting caprophyl disease therapy, wherein, during use, the ight soil just obtained is put into extraction tube, rapidly by the opening heated sealant (or using heat sealing machine sealing) of body, syringe is used to find time to body through fluid injection end, and then use syringe to pass fluid injection end in body, inject diluent (as physiological saline or milk etc.), manual squeezing, rub and make ight soil and diluent fully be mixed to get fecal suspension, then folder is extracted by rotating the adjustment of ears nut, make the distance between extrusion roll just or be slightly less than the thickness of body, pull roll shaft from top to bottom, fecal suspension is made step by step through filtering net by the squeeze of two rollers and gravity, because the aperture of filtering net reduces step by step, the material that every one-level filtering net stores is all not identical, every one-level all has liquid pumping side, different target components can be extracted according to demand.
Accompanying drawing explanation
Fig. 1 is the structural representation of extraction tube in the specific embodiment of the invention.
Fig. 2 is the structural representation extracting folder in the specific embodiment of the invention.
Wherein, Reference numeral is: 1, drain side; 2, filtering net; 3, body; 4, opening; 5, fluid injection end; 6, liquid pumping side; 7, limited impression; 8, ears nut; 9, roller; 10, lead screw; 11, roll shaft.
Embodiment
For the technical characterstic of this programme can be clearly demonstrated, below by embodiment, this programme is set forth.
See Fig. 1, the present invention is a kind of disposable intestinal contents target component extraction element, comprise extraction tube, extraction tube comprises only upper end open and can the body 3 of hot-seal and 18 grades of filtering net 2 be connected with the inner wall sealing of body 3, body 3 also comprises the drain side 1 of lower end, be arranged on the fluid injection end 5 on body 3 sidewall and liquid pumping side 6, fluid injection end 5 is between upper end open 4 and the filtering net 2 of the first step, liquid pumping side 6 is between two adjacent head nets 2, filtering net 2 from top to bottom aperture (namely filtering net considers the diameter in hole) is the trend reduced step by step, namely the aperture of adjacent two-stage filtration net 2 can be identical, body 3 is soft polymer material, the aperture of filtering net is 0.0004-5.00mm, the material of body 3 is silica gel, and one-body molded, body is right cylinder or cubes.
Wherein, see Fig. 2, the present invention also comprise with extraction tube with the use of extraction press from both sides, extraction folder comprises two parallel extrusion rolls, extrusion roll comprises roll shaft 11 and can along the roller 9 of roll shaft 11 radial rotary, the two ends of roll shaft 11 are symmetrically arranged with through hole, and two extrusion rolls are connected with ears nut 8 by the lead screw 10 through through hole.The screw terminal of lead screw 10 is yi word pattern, is provided with yi word pattern limited impression 7 with on the roll shaft 11 of screw terminal correspondence position; Wherein, the annexation of roller 9 and roll shaft 11 is prior art, does not repeat them here.
During use, the ight soil just obtained is put into extraction tube, rapidly by opening 4 heated sealant (or using heat sealing machine sealing) of body 3, syringe is used to find time through fluid injection end 5 pairs of bodys 3, and then use syringe to pass fluid injection end 5 to inject diluent (as physiological saline or milk etc.) in body 3, manual squeezing, rub and make ight soil and diluent fully be mixed to get fecal suspension, then folder is extracted by rotating the adjustment of ears nut 8, make the distance between extrusion roll just or be slightly less than the thickness of body 3, pull roll shaft 11 from top to bottom, fecal suspension is made step by step through filtering net 2 by the squeeze of two rollers 9 and gravity, because the aperture of filtering net 2 reduces step by step, the material that every one-level filtering net 2 stores is all not identical, every one-level all has liquid pumping side 6, different target components can be extracted according to demand.Structure of the present invention is simple, easy to operate, and the just bacterium survival rate extracted is high, quality is high.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (3)

1. a disposable intestinal contents target component extraction element, it is characterized in that, comprise extraction tube, described extraction tube comprises only upper end open and the filtering net that is connected with the inner wall sealing of described body with some levels of the body that can seal, described body also comprises and is arranged on fluid injection end on described tube wall and liquid pumping side, described fluid injection end is between upper end open and the described filtering net of the first step, described liquid pumping side is between two adjacent described filtering nets, described filtering net from top to bottom aperture is the trend reduced step by step, described body is soft polymer material, the material of described body is silica gel, soft rubber, PVC or soft plastics, and it is one-body molded,
Also comprise with described extraction tube with the use of extraction press from both sides, described extraction folder comprises two parallel extrusion rolls, described extrusion roll comprises roll shaft and can along the roller of described roll shaft radial rotary, the two ends of described roll shaft are symmetrically arranged with through hole, and two described extrusion rolls are connected with ears nut by the lead screw through described through hole.
2. disposable intestinal contents target component extraction element according to claim 1, is characterized in that, the aperture of described filtering net is 0.0004-5.00mm.
3. disposable intestinal contents target component extraction element according to claim 1 and 2, is characterized in that, the screw terminal of described lead screw is yi word pattern, is provided with yi word pattern limited impression with on roll shaft described in described screw terminal correspondence position.
CN201410484176.9A 2014-09-19 2014-09-19 A kind of disposable intestinal contents target component extraction element Expired - Fee Related CN104212707B (en)

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Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106399068B (en) * 2016-08-31 2018-12-25 孟素兰 A kind of device preparing liquid manure manually
CN106190793B (en) * 2016-08-31 2018-12-25 孟素兰 A kind of liquid manure Preparation equipment
CN107513515A (en) * 2017-10-20 2017-12-26 南京益恒寿生命科技有限公司 A kind of caprophyl transplantation treatment Plays caprophyl liquid preparing process
CN109174382A (en) * 2018-09-19 2019-01-11 北京新星靓京广医疗美容医院有限公司 A kind of device of point-to-point orientation fat transfer
CN113528324B (en) * 2021-09-16 2022-01-04 迈德(山东)科技股份有限公司 Microorganism filtering and extracting device and filtering and extracting method

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2892868Y (en) * 2005-12-06 2007-04-25 刘瑞东 Cell detaching tube
CN202315526U (en) * 2011-11-16 2012-07-11 高晓华 Filtering device for gastric lavage machine
CN103330961A (en) * 2013-02-08 2013-10-02 常州德天医疗器械有限公司 Medical device for recovering targeted components of cavity content
CN103418295A (en) * 2007-06-21 2013-12-04 简.探针公司 Appratus and means for contents of mixing detection receptacle

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8546127B2 (en) * 2008-06-30 2013-10-01 General Electric Company Bacteria/RNA extraction device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2892868Y (en) * 2005-12-06 2007-04-25 刘瑞东 Cell detaching tube
CN103418295A (en) * 2007-06-21 2013-12-04 简.探针公司 Appratus and means for contents of mixing detection receptacle
CN202315526U (en) * 2011-11-16 2012-07-11 高晓华 Filtering device for gastric lavage machine
CN103330961A (en) * 2013-02-08 2013-10-02 常州德天医疗器械有限公司 Medical device for recovering targeted components of cavity content

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Inventor after: Li Li

Inventor after: Wang Yujie

Inventor after: Guo Xia

Inventor after: Miao Cui

Inventor before: Liang Diecong

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Effective date of registration: 20151208

Address after: 266000 Jiaozhou Road, Shandong, China, No. 1, No.

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Address before: 250000 Shandong City, Ji'nan, No. ten via road 4, building 4, unit 25156, 402

Applicant before: Liang Diecong

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Termination date: 20170919