CN103736212B - A kind of bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency - Google Patents

A kind of bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency Download PDF

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CN103736212B
CN103736212B CN201310712802.0A CN201310712802A CN103736212B CN 103736212 B CN103736212 B CN 103736212B CN 201310712802 A CN201310712802 A CN 201310712802A CN 103736212 B CN103736212 B CN 103736212B
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pedal
stress
motor
high frequency
vibration
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CN103736212A (en
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景达
罗二平
翟明明
申广浩
吴小明
谢康宁
汤池
郭伟
刘娟
姜茂刚
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Fourth Military Medical University FMMU
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Abstract

The invention discloses a kind of bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency, including the bed body being respectively arranged at two ends with headrest and pedal, angle demodulator it is configured with bottom bed body, the bed body of angle demodulator regulation headrest side upwards heightens 0~10 °, the preload force that pedal is applied by gravity, pedal contacts with motor, produces vibratory stimulation by the drive of motor;Control platform and pass through feedback control module, linear electric motors are controlled.Present invention employs horizontal direction vibration wave to stimulate, and head of a bed scalable, heightening slant range is 0 10 °, on the one hand for ease of the more preferable stress of patient, head foot distance can regulate according to patient's height, on the other hand can be by the prestrain stress of the gravity of patient body, it is possible to the significantly bone resorption rate of the sufferers of osteoporosis face of suppression estrogen deficiency induction, thus suppress bone loss.

Description

A kind of bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency
Technical field
The invention belongs to bone injury and osteoporosis treatment technical field, relate to one and shake by force based on high frequency is low Dynamic bone injury/osteoporosis therapeutic bed.
Background technology
Bone injury and osteoporosis are most commonly seen clinical diseases, and its clinical onset rate is high, for disease The health suffered from and psychology all cause burden greatly.Osteoporosis clinical manifestation be bone amount reduce, bone crisp Property increase and and the fine structure of osseous tissue destroy, often cause generation and the limb function permanent loss of fracture. According to statistics, there is a sufferers of osteoporosis face more than 200,000,000 in the whole world, and China patient numbers the most up to 90,000,000 it Many, China reaches more than 108,000,000,000 RMB for osteoporotic medical economics is also costly every year, bone The high disability rate of matter osteoporotic fractures and fatality rate are also one of clinical great difficult problems.Along with China's population The speed aggravation of aging, " the quiet killer " of osteoporosis this phagocytosis senior health and fitness, to institute of China The economy brought and burden on society are also increasing the weight of year by year.Meanwhile, at full speed along with China's space industry Development, the severe bone Loss appeared in astronaut space flight have also been obtained Aero-Space worker Extensive concern.Secondly, clinically, the disease such as fracture, Cranial defect, bone does not connect is also clinic bone Modal osteopathia on surgery, the most quickly repairs bone injury disease and the height that reduces it caused is lethal Rate and disability rate are one of significant challenge of facing clinically.Based on a people average fracture 1-2 time Calculating, China occurs the height of the case of fracture to well imagine every year.
At present, traditional clinical treatment medication medication method promoting osteogenesis mainly has: (1) calcium preparation, Include escape happy, Kai Sili, Gaierqi D (vitamin D3 and calcium carbonate), happy power, calcium gluconate oral solution with effect, imperial prosperous calcium+D Oral liquid, strength obtain calcium, huge energy calcium and micro-calcium;(2) suppression bone resorption medicine, heir as pregnant in dehydrogenation, times U.S. power sheet and livial etc.;Bisphosphonates, such as Fosamax, bone unicorn, Bang get Lin and Ji Li oxazepan;(3) Promoting bone growing class medicine, such as growth hormone, insulin like growth factor, parathyroid hormone etc.;(4) promote Enter the vitamin medicaments of mineralising, as method can (l alpha-hydroxy vitamin D 3), Rocaltrol (calitriol), Sprout lattice prosperous (alfacalcidol), vertical celebrating (alfacalcidol sheet).
Current drug treatment also exists significantly and widely clinical practice limitation, mainly includes valency Lattice are high and drug side effect obvious, make osteoporosis and promote clinical prevention and the treatment of bone injury healing It is still a thorny difficult medical problem.Therefore, the method exploring more effective and safe non-drug therapy There is highly important medical science and social value, and the trouble of vast economically underdeveloped area can be benefited Person.
The Wolff law proposition that 19th century are famous: skeleton is as the stress bearing system of body, and it can Make adaptive change by the structure changing self with stress stimulation to external world, and OP generation is main One of reason is exactly that the mechanical load on skeleton is not enough or skeleton self stress response ability fails, and causes bone Calcium is lost in a large number, and then induction OP.Substantial amounts of research shows, answering of ectogenic applying physiological level Power load (range of strain is 500-2000 μ ε) has significantly rush bone synergistic effect, discloses stress and carries Lotus is for maintaining bone mass and the importance of bone metabolism.The Rubin of U.S. Stony Brook University Professor seminar in last century Mo find ectogenic applying low-intensity first, the vibratory stimulation of high frequency can The significantly suppression osteoporotic generation of turkey and development.Scientists finds subsequently, low-intensity (< 50 μ ε), the vibratory stimulation of high frequency (20-100Hz) has and significantly promotes osteogenesis speed, accelerates bone ore deposit Synthesis and the effect of suppression bone resorption.Meanwhile, some animal experiment studies also confirm, this vibration Model of action can promote the healing of animal long bone fracture, discloses it and is applied to clinical osteoporosis and bone The bright prospects of injury in treating.But, the action method of current document report is required to subject animal Or patient stands on vibration platen so that it is cannot apply to act on for a long time, the most also can be to being treated The comfort level of sufferer brings the biggest impact.Facing it addition, this method the most greatly constrains this method Application in bed fracture, bone does not connect and Cranial defect patient.
Summary of the invention
A kind of bone injury/osteoporosis based on the low strong vibration of high frequency of offer is provided Therapeutic bed, so that patient realizes the treatment of osteoporosis or bone injury when the most comfortable, Overcome and cannot apply long defect.
The present invention is to be achieved through the following technical solutions:
A kind of bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency, including being respectively arranged at two ends with head Pillow and the bed body of pedal, be configured with angle demodulator, angle demodulator regulation headrest side bottom bed body Bed body upwards heighten 0~10 °, the preload force that pedal is applied by gravity, pedal connects with motor Touch, produce vibratory stimulation by the drive of motor;
Pressure transducer gathers the stress loading intensity that applied of pedal, and pressure transducer will be gathered Stress signal is sent to data collecting card, is resent to control platform, controls the platform information to being received Display in real time, controls platform and sends feedback control signal also by feedback control module to motor.
Distance between described headrest and pedal is adjustable, contacts with the recess sidewall of headrest with head, Foot is in close contact with pedal and is adjusted.
Described bed body is also configured with multiple fixing bandage, is respectively used to fixing limbs and waist, by solid Determine after bandage is fixed, to avoid health deviation axial location in pedal vibration processes.
Described driven by motor pedal produces vibration, produces the axial compression stress putting on human body.
Described pressure transducer is arranged between motor and pedal, and pressure transducer should by gathered Force signal, after signal conditioner filtering amplified device are amplified, is sent to data collecting card.
The described platform that controls receives the stress signal that pressure transducer is sent, by feedback control module to Processor sends signal, and processor drives motor to pedal loading stress, feedback by movement controller Motor is adjusted by control module with Stress Control pattern so that it is produce constant stress loading.
Described feedback control module also receives and controls the Vibration Parameter that platform is inputted by touch pad, to electricity The stress that machine loads to pedal is adjusted.
Described driven by motor pedal produce oscillation intensity be 1~1000g the most adjustable, frequency be 1~ The linear adjustable axial vibration ripple of 100Hz.
Compared with prior art, the present invention has a following useful technique effect:
Bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency that the present invention provides, have employed level Direction vibration wave stimulates, and vibration therapy of the prior art is vertical direction, vibrates without horizontal direction Report, but fracture and osteoporosis patient stand or stand for a long time the most inconvenient;And head of a bed scalable, Heightening slant range is 0~10 °, and on the one hand for ease of the more preferable stress of patient, head foot distance can root Regulate according to patient's height, on the other hand can be by the prestrain stress of the gravity of patient body;
Further, use and control platform and carry out feedback control, feedback system can observing and controlling patient foot stress, To ensure that in treatment, institute's loading stress is as constant force, and carry out the regulation of power and the frequency loaded, it is ensured that high Frequently, the therapeutic effect of low-intensity vibration.
Bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency that the present invention provides, it is possible to more The treatment of osteoporosis or bone injury is realized under comfortable state;For preventing patient during vibration therapy Move and make troubles to treatment, present invention adds extremity and waist strip design;And angle demodulator is adjusted Patient can be treated in the way of using easier acceptance.
Bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency that the present invention provides, it is provided Vibration therapy, it is possible to the significantly bone resorption rate of the sufferers of osteoporosis face of suppression estrogen deficiency induction, Thus suppress bone loss.Clinical study results shows, vibration therapy can significantly inhibit the bone of menopausal women The development of matter osteoporosis.Its design concept is unique, simple and practical, easy to operate, use safety.This The indication of bright design has: the 1) osteoporosis of each factor induction, as postmenopausal women, useless use, diabetes, Excessive drinking etc.;2) fracture, fracture delayed union, bone does not connect and osteanabrosis;3) adjuvant clinical is commonly used Biological bone repair materials treatment Cranial defect;4) stress fracture.
The adaptation treatment crowd of this invention design has: 1) menopausal women;2) due to disease long-term bed Old people;3) motion and the middle age of sun exposure are lacked;4) people of microgravity environment it is exposed to for a long time Group's (such as spaceman);5) diabetes and the osteoporosis crowd caused by excessive drinking;6) fracture, bone Do not connect, bone delay in healing, osteanabrosis and the patient of Cranial defect;7) stress fracture crowd is (as army fights Scholar, athlete etc.).
Accompanying drawing explanation
Fig. 1 is the structural representation of the present invention, in figure: 1, headrest;2, angle demodulator;3, control Platform;4, motor;5, pressure transducer;6, pedal;7, fixing bandage;
Fig. 2 is the schematic diagram of the signals collecting of the present invention, control;
Fig. 3 be control platform for treatment patient's output intensity be 8mN, frequency be axially shaking of 20Hz Dynamic ripple stimulates.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail, described in be to the present invention Explanation rather than restriction.
Seeing Fig. 1, a kind of bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency, including two ends Being respectively equipped with headrest 1 and the bed body of pedal 6, be configured with angle demodulator 2 bottom bed body, angle is adjusted The bed body of joint device 2 regulation headrest 1 side upwards heightens 0.1~10 °, and pedal 6 is applied by gravity Preload force, pedal 6 contacts with motor 4, produces vibratory stimulation by the drive of motor 4;
Pressure transducer 5 gathers the stress loading intensity that pedal 6 is applied, and pressure transducer 5 is by institute The stress signal gathered is sent to data collecting card, is resent to control platform 3, controls platform 3 to institute The information received shows in real time, controls platform 3 and sends feedback control also by feedback control module to motor 4 Signal processed.
Further, the distance between described headrest 1 and pedal 6 is adjustable, with head and headrest 1 Recess sidewall contact, the close contact of foot and pedal 6 is adjusted.
Described bed body is also configured with multiple fixing bandage 7, is respectively used to fixing limbs and waist, passes through Health deviation axial location in pedal 6 vibration processes is avoided after fixing bandage 7 is fixing.Described motor 4 drive pedal 6 to produce vibration, produce the axial compression stress putting on human body.
Concrete, patient is flat to crouch on therapeutic bed, patients head and the sidewall contact of headrest, and headrest 1 sets Having the groove adapted with head, foot's base plate of patient and pedal keep being in close contact, pedal with One for producing the linear electric motors contact of vibration, by the drive of motor, pedal produce altofrequency, Low intensive vibratory stimulation.
And, can adjust different according to the difference of the height of patient for producing the pedal of vibration Position.There is the bandage for immobilized patients extremity and waist the both sides of therapeutic bed, prevent from applying vibration During patient health deviation axial location.Before applying vibratory stimulation, suitably by therapeutic bed near suffering from Person's head one heightens 5-10 ° on the side, so that what the fixing pedal of vibration was applied by patient body gravity Prestrain effect.Oscillation intensity is that 1-1000g is the most adjustable, and frequency is that 1-100Hz is the most adjustable.
Seeing Fig. 2, described pressure transducer 5 is arranged between motor 4 and pedal 6, and pressure passes The stress signal gathered after signal conditioner filtering amplified device are amplified, is sent to by sensor 5 Data collecting card.
The described platform 3 that controls receives the stress signal that pressure transducer 5 is sent, by feedback control mould Block sends signal to processor, and processor drives motor 4 to load to pedal 6 by movement controller should Power, motor 4 is adjusted by feedback control module with Stress Control pattern so that it is produce constant stress Load.
Concrete, the pressure transducer between the fixing pedal of linear electric machine and vibration experiences stress, After being modulated by stress signal, filtering, amplify, it is sent to data collecting card and feedback control module;Logical Cross feedback control module to feed back to movement controller and microprocessor and be adjusted controlling motor with this Make, thus ensure system be operated in accurately under Stress Control pattern (i.e. stress loading device produce constant Stress loading effect), to controlling platform, so that carrying out treating parameter, to be set for vibration dynamic in display simultaneously Make.Feedback control module also receives and controls the Vibration Parameter that platform 3 is inputted by touch pad, to motor 4 The stress loaded to pedal 6 is adjusted.
It is 1~1000g the most adjustable, frequency that described motor 4 drives pedal 6 to produce oscillation intensity It it is 1~100Hz linear adjustable axial vibration ripple.
The one provided based on the synergistic bone injury of many physical agents and osteoporosis therapeutic bed, When treatment service is provided:
When patient fixes and regulates pedal with headrest distance to after being suitable to patient's height, suitably by therapeutic bed Heighten 5-10 ° on the side near patients head one, make movement controller loading stress, be positioned at linear electric machine With the pressure transducer between the fixing pedal of vibration experiences stress, stress signal is modulated, filters, put After great, it is sent to data collecting card and feedback control module;Can be fed back to by feedback control module Movement controller and microprocessor are adjusted controlling motor action with this, thus ensure the accurate work of system Making under Stress Control pattern, display simultaneously is to controlling platform so that carrying out treating parameter to be set for vibration Action.
Embodiment 1
The present embodiment detailed process is as follows:
Female postmenopausal osteoporosis patient totally 48, age 52-64 year, use Dual X-ray bone Density Measuring Instrument (being purchased from Lunar company of the U.S.) measures L2-4Bone density, bone density is below corresponding age bracket Bone density peak value.All patient's hearts, liver, kidney and other endocrine metabolism states are all normal, in 3 months The medicine person of class without long-term steroid.
Before treatment, all object of study all empty stomach venous blood samples when the morning 9, take serum after being centrifuged and are placed in -20 DEG C of preservations are stand-by.Enzyme immunoassay is used to measure the anti-tartaric acid of serum in kits blood samples of patients The content of phosphatase 5b.48 example patients are equally divided into according to age, bone density and level of bone gla protein in serum Vibration therapy group and estrin treatment group, often group 24.Vibration group row intensity is 8mN, frequency is 20 The axial vibration ripple of Hz stimulates (waveform is as shown in Figure 3), 4 hours every days, continuous action 60 days.Female Steroid group takes livial 1 every day, takes 60 days continuously.
After treatment is finished, all object of study all empty stomach venous blood samples measurement patient's blood when the morning 9 The content of clear tartrate resistant phosphatase 5b.Subsequently, two groups of patients all use Dual-energy X-rays absorptionmetry to survey Amount L2-4Bone density.Result of study is as shown in table 1~2:
The bone density of two groups no difference of science of statistics before the treatment, after the treatment of 60 days, estrin treatment group Bone density before bone density after treatment is significantly higher than treatment (P < 0.05), after the treatment of same vibration therapy group Before being significantly higher than treatment (P < 0.05), show that vibration therapy is for improving the bone density tool of sufferers of osteoporosis face There is significant facilitation.Equally, the content of the tartrate resistant phosphatase 5b after the treatment of vibration therapy group shows Before writing less than treatment, show the sclerotin that the vibration therapy of 60 days can significantly suppress estrogen deficiency to induce The bone resorption rate of loose patient, thus suppress bone loss.This clinical study results shows, vibration therapy The development of the osteoporosis of menopausal women can be significantly inhibited.
Table 1 patient rear L before the treatment2-4Bone density (g/cm2) situation of change
Table 2 patient before the treatment after serum tartrate resistant phosphatase 5b(U/L) situation of change
Embodiment 2
The present embodiment detailed process is as follows:
Clinical 18 example Patients with Fractures of Lower Limbs, male 10 examples, female 8 example, minimum 26 years old of age, maximum 53 In year, the axial vibration ripple that use intensity is 8mN, frequency is 20Hz stimulates (waveform is as shown in Figure 3), Once a day, act on 1 hour, continuous action 45 days every time.
The evaluation criterion of curative effect is: (1) is effective: freely, functional activity recovers normal to joint motion, office Portion's swelling is disappeared, without tenderness and discomfort.(2) take a turn for the better: ankylosis makes moderate progress, range of motion Relatively increasing before treatment, swelling is disappeared, slightly uncomfortable.(3) invalid: the vibration therapy of 45 days is for fracture Sings and symptoms be not improved.
Result of study after 45 days shows: after vibration therapy, effective case totally 7 example, the case of improvement Totally 10 example, Ineffective Cases 1 example.This clinical trial results shows, vibration therapy is for promoting fracture patient Union of fracture, accelerate bone injury reparation there is remarkable result.

Claims (7)

1. bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency, it is characterised in that bag Include and be respectively arranged at two ends with headrest (1) and the bed body of pedal (6), bottom bed body, be configured with angular adjustment Device (2), angle demodulator (2) regulates the bed body of headrest (1) side and upwards heightens 0~10 °, foot The preload force that pedal (6) is applied by gravity, pedal (6) contacts, by electricity with motor (4) The drive of machine (4) produces vibratory stimulation;
Pressure transducer (5) gathers the stress loading intensity that pedal (6) is applied, pressure transducer (5) stress signal gathered is sent to data collecting card, is resent to control platform (3), controls The information received is shown by platform (3) in real time, control platform (3) also by feedback control module to Motor (4) sends feedback control signal, to ensure that in treatment, institute's loading stress is as constant force;
Described motor (4) drive pedal (6) produce oscillation intensity be 1~1000g the most adjustable, Frequency is 20~100Hz linear adjustable axial vibration ripples.
2. bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency as claimed in claim 1, It is characterized in that, the distance between described headrest (1) and pedal (6) is adjustable, with head and head The recess sidewall contact of pillow (1), foot is in close contact with pedal (6) and is adjusted.
3. bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency as claimed in claim 1, It is characterized in that, described bed body is also configured with multiple fixing bandage (7), be respectively used to fixing limbs and Waist, avoids health deviation in pedal (6) vibration processes axial after being fixed by fixing bandage (7) Position.
4. bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency as claimed in claim 3, It is characterized in that, the bed body of described angle demodulator (2) regulation headrest (1) side upwards heighten 5~ 10 °, motor (4) drives pedal (6) to produce vibration, produces the axial compression stress putting on human body.
5. bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency as claimed in claim 1, It is characterized in that, described pressure transducer (5) is arranged between motor (4) and pedal (6), The stress signal gathered is filtered and after the amplification of amplified device by pressure transducer (5) through signal conditioner, It is sent to data collecting card.
6. bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency as claimed in claim 1, It is characterized in that, described control platform (3) receives the stress signal that pressure transducer (5) is sent, Sending signal by feedback control module to processor, processor drives motor (4) by movement controller To pedal (6) loading stress, motor (4) is adjusted by feedback control module with Stress Control pattern Joint so that it is produce constant stress loading.
7. bone injury/osteoporosis therapeutic bed based on the low strong vibration of high frequency as claimed in claim 6, It is characterized in that, described feedback control module also receives control platform (3) by shaking that touch pad inputs Dynamic parameter, the stress loaded motor (4) to pedal (6) is adjusted.
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CN107715311A (en) * 2017-11-10 2018-02-23 长春先盈医疗科技有限公司 A kind of osteoporosis therapy machine
CN108498953A (en) * 2018-04-20 2018-09-07 刘西纺 Osteoporosis treatment instrument
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