CN103621938A - Food, health-care product or medicinal composition for improving gastronintestinal digestion function - Google Patents
Food, health-care product or medicinal composition for improving gastronintestinal digestion function Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
- A23L7/10—Cereal-derived products
- A23L7/152—Cereal germ products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a food, a health-care product or a medicinal composition for improving the gastronintestinal digestion function. The food, health-care product or medicinal composition is a preparation prepared from the following raw materials in parts by weight: 10-15 parts of yam, 10-15 parts of malt, and 3-5 parts of fennel. The invention also provides a preparation method and application of the food, the health-care product or the medicinal composition. After yam, malt and fennel are used in a combined manner, the food, the health-care product or the medicinal composition has a remarkable effect of improving the gastronintestinal digestion function, and a new choice of foods, health-care products or medicines is provided to clinical application.
Description
Technical field
The present invention relates to a kind of food, health products or pharmaceutical composition that improves digestive functions and its production and use.
Background technology
Taste are reservoir of food and drink, the foundation of acquired constitution, source of generating QI and blood.If the spleen being blocked by dampness, transformation failure of spleen, clear QI failing to ascend, can affect stomach received with fall, occur food less, vomiting, feel sick, the disease such as abdominal fullness and distention.Otherwise, if intemperance of taking food, retention of food in the stomach, stomach Qi rising, often can affect the clear and transporting of the liter of spleen, there is the abdominal distension disease such as have loose bowels.The traditional Chinese medical science has cloud: taste imbalance all kinds of diseases and ailments are raw.Digestive functions is unbalance is one of main manifestations of taste imbalance.
For the unbalance disease of gastro-intestinal digestion, adopt at present Chinese medicine effect better, as conventional ageratum oral liquid, its main component is: patchouli oil, perilla leaf oil, the root of Dahurain angelica, rhizoma atractylodis, the bark of official magnolia (ginger system), the raw tuber of pinellia, Poria cocos, dried orange peel, the shell of areca nut, extract of licorice root, can be used for treating abdominal distention, the vomiting disease such as have loose bowels; Classical Jianpi Wan (< < Standards of Diagnosis and Treatment > >) is comprised of the bighead atractylodes rhizome, the banksia rose, the coptis, Radix Glycyrrhizae, PORIA ALBA, ginseng, Divine Comedy, dried orange peel, fructus amomi, coloured malt, hawthorn, Chinese yam, nutmeg, can be used for strengthening the spleen and stomach, antidiarrheal helps digestion.
Yet in conventional prescription, flavour of a drug are more, certainly will bring higher treatment cost to patient at present.Therefore, research and develop a kind of flavour of a drug composition Traditional Chinese medicine composition few and evident in efficacy and seem particularly necessary.Yet there are no Chinese yam, Fructus Hordei Germinatus, fennel seeds three taste medicine compatibilities for improving the report of digestion function of stomach and intestine.
Summary of the invention
The object of the present invention is to provide a kind of food, health products or pharmaceutical composition that improves digestive functions.Another object of the present invention is to provide preparation method and the purposes of this food, health products or pharmaceutical composition.
The invention provides a kind of food, health products or pharmaceutical composition that improves digestive functions, it is the preparation that the raw material by following weight proportion is prepared from: 10～15 parts of Chinese yams, 10～15 parts, Fructus Hordei Germinatus, 3～5 parts of fennel seeds.
Preferably, it is the preparation that the raw material by following weight proportion is prepared from: 15 parts of Chinese yams, 10 parts, Fructus Hordei Germinatus, 3 parts of fennel seeds.
Wherein, described preparation is by the medicinal powder of each bulk drug, the water of bulk drug, or/and ethanol extract is active component, adds the preparation that auxiliary material conventional in pharmacy or health products or complementary composition are prepared from.
Further, described preparation is oral formulations.
Further, described oral formulations is paste, oral liquid, medicinal tea, granule, capsule, pill, tablet or powder.
The present invention also provides the preparation method of above-mentioned food, health products or pharmaceutical composition, and it comprises the steps:
(1) take by weight ratio each bulk drug;
(2) each bulk drug directly pulverized or added water or/and after alcohol extract, add auxiliary material conventional in pharmacy or health products or complementary composition, being prepared into conventional preparation, obtaining.
The present invention also provides above-mentioned food, health products or pharmaceutical composition to improve the purposes in food, health products or the medicine of digestive functions in preparation.
Wherein, described food, health products or medicine are to have the intestinal motility of promotion, gastric secretion, improve food, health products or the medicine of peptic activity of stomach.
Food provided by the invention, health products or pharmaceutical composition can be by promoting intestinal motility, promote gastric secretion, improving the number of ways such as peptic activity of stomach, significantly improve digestive functions, clear efficacy is the clinical selection that a kind of new medicine and health products are provided.
The specific embodiment
The preparation of embodiment 1 food of the present invention, health products or medicine
Get Chinese yam 15g, Fructus Hordei Germinatus 10g, fennel seeds 3g, boiling is extracted 3 times, decocts 0.5h at every turn, merges decocting liquid, after concentrating, adds appropriate filler, prepares particle.
The preparation of embodiment 2 food of the present invention, health products or medicine
Get Chinese yam 10g, Fructus Hordei Germinatus 15g, fennel seeds 3g, add 75%v/v alcohol extract 2 times, alcohol extract is standby, and dregs of a decoction boiling is extracted 2 times, and decocting liquid is standby; Alcohol extract is reclaimed after ethanol, merge with decocting liquid, after concentrating, add appropriate filler, prepare particle, compressing tablet obtains tablet.
The preparation of embodiment 3 food of the present invention, health products or medicine
Get Chinese yam 13g, Fructus Hordei Germinatus 10g, fennel seeds 5g, 65%v/v alcohol extract 3 times, merges alcohol extract, and spraying is dry, adds appropriate filler, prepares capsule.
By concrete pharmacodynamic experiment, prove beneficial effect of the present invention below
Test example 1 present composition promotes the investigation of digestive function
1 experiment material
1.1 these experiments of Experimental agents are set 3 kinds of various dose proportioning groups and are carried out preliminary screening, are respectively proportioning group 1(Chinese yam: Fructus Hordei Germinatus: fennel seeds=5:3.33:1, i.e. Chinese yam 15g, Fructus Hordei Germinatus 10g, fennel seeds 3g); Proportioning group 2(Chinese yam: Fructus Hordei Germinatus: fennel seeds=3.33:5:1, i.e. Chinese yam 10g, Fructus Hordei Germinatus 15g, fennel seeds 3g); Proportioning group 3(Chinese yam: Fructus Hordei Germinatus: fennel seeds=2.6:2:1, i.e. Chinese yam 13g, Fructus Hordei Germinatus 10g, fennel seeds 5g).Water boiling and extraction in above-mentioned prescription, concentrates to obtain thick paste, and being mixed with concentration is that 47g crude drug in whole/100ml medicinal extract sample is standby.
Ageratum oral liquid (Taiji Group Chongqing Fuling Pharmaceutical Factory Co., Ltd., lot number: 13060281)
1.2 animal used as test KM mouse, Da Shuo bio tech ltd, Chengdu provides, and body weight 18-22g is male, the animal quality certification number: animal credit number: SCXK(river) 2008-24; SD rat, Chengdu University of Traditional Chinese Medicine's Experimental Animal Center provides, and body weight 140g～160g is male, the animal quality certification number: SCXK(river) 2008-11
1.3 experiment reagents and instrument electronic balance (one thousandth precision, 0.1g); Loperamide hydrochloride (Xi'an Yang Sen company, lot number: 031014878); Gum arabic, prepared Chinese ink.
2 experimental techniques
2.1 impacts on intestinal motility
72 of male KM mouse, divide 6 groups at random, comprise 3 kinds of different proportioning administration groups, blank group, ageratum oral liquid group and model control group, 12 of every treated animals.10 times of (4.7g crude drug/kgBW) per os with human body consumption per day give 3 kinds of different proportioning given the test agent, 10 times of ageratum oral liquid 3.3ml/kgBW(adult consumptions), 1 time/d, continuous 15d, blank group and model control group give experimental water by same volume.Give after given the test agent 15d, each is organized mouse fasting and can't help water 16h.After 30min, model control group and 4 administration group gavages give compound diphenoxylate (5mg/kgBW), and blank group to experimental water.Give after compound diphenoxylate 30min, 4 administration groups contain the prepared Chinese ink (activated carbon powder, 10% gum arabic containing 5%) of corresponding given the test agent, and blank group and model control group give prepared Chinese ink.After giving prepared Chinese ink 25min, disconnected neck is put to death animal, anatomical isolation mesenterium, take out pylorus (upper end) to the little intestinal tube of ileocecus (lower end), be placed in pallet, gently draw intestinal tube to be in line, measure small intestine total length, prepared Chinese ink advances length (pylorus is to prepared Chinese ink forward position), is calculated as follows prepared Chinese ink impelling ratio (P) and prepared Chinese ink propelling rate:
Prepared Chinese ink impelling ratio (P)=prepared Chinese ink advances length (cm)/small intestine total length (cm)
Prepared Chinese ink propelling rate
Adopt SPSS12.0 software to carry out statistical analysis to each proportioning group result and blank group, model control group.
2.2 impacts on digestive enzyme activity
50 of male SD rats, divide 5 groups at random, comprise 3 kinds of different proportioning administration groups, blank group, ageratum oral liquid group, 10 of every treated animals, and the difference of the weight of animals should be no more than 10% of average weight.With 10 times (4.7g crude drug/kgBW) of human body consumption per day, per os gives 3 kinds of different proportioning given the test agent, 10 times of ageratum oral liquid 3.3ml/kgBW(adult consumptions), 1 time/d, continuous 30d, blank group gives experimental water by same volume.After last administration, water 24h is can't help in each treated animal fasting, adopts etherization rat pylorus ligature law to collect the gastric juice of discharging in certain hour, gastric juice amount in the analytical unit time.Get the conical flask that gastric juice 1mL puts into 50mL, add 0.05mol/L hydrochloric acid solution 15mL to shake up, put into the protein pipe of made fresh and (select internal diameter 1.5mm glass tube, injection Fresh Egg is clear, put in hot bath and keep flat and make to take out after protein coagulating, discard alveolate protein pipe, put Refrigerator store, make before use 3cm length) two pieces.Fill in bottleneck, in 37 ℃ of insulating boxs, hatched 24h, taken out protein pipe, with chi, measured the length (mm) of protein pipe two ends transparent part, with the value of four ends, asked its mean value.Calculate pepsin activity and pepsin discharge rate.
Pepsin activity unit (U/mL)=tetra-end protein pipe transparent part length average
2* 16
Pepsin discharge rate (U/h)=pepsin activity * gastric juice amount per hour
Adopt SPSS12.0 software to carry out statistical analysis to each proportioning group result and blank group, model control group.
3 experimental results
Different prescription proportionings to the experimental result of mouse small intestine motion effects in Table 1:
The impact of the different prescription of table 1 proportioning on mouse prepared Chinese ink propelling rate
Note: with model control group comparison, * P<0.05, * * P<0.01; Compare with proportioning group 1,
△p < 0.05,
△ △p < 0.01.
From table 1, model control group prepared Chinese ink impelling ratio and propelling rate, all significantly lower than blank group (P<0.05), show Constipated mice establishment.Compare with model control group, the different proportioning groups of medicine of the present invention/health food, ageratum oral liquid all can significantly promote intestinal motility (P<0.05, P<0.01), wherein the prepared Chinese ink propelling rate of 1 pair of mouse of proportioning group has utmost point significant difference.The prepared Chinese ink propelling rate of 1 pair of mouse of compatibility group is significantly better than compatibility group 3 and compatibility group 4(P<0.05), act on more obvious.
Different prescription proportionings to the sex experimental result of rat digestive enzyme in Table 2:
The impact of the different prescription of table 2 proportioning on rat digestive ferment
Note: with the comparison of blank group, * P<0.05, * * P<0.01; Compare with proportioning group 1,
△p < 0.05,
△ △p < 0.01.
From table 2, compare with blank group, the rat stomach protease discharge rate of the different proportioning groups of medicine of the present invention/health food, ageratum oral liquid all has significant difference (P<0.05, P<0.01), and proportioning group 1 utmost point conspicuousness effect (P<0.01), can significantly improve rat stomach prolease activity, promote rat gastric secretion to increase (P<0.05).Compatibility group 1 improves rat stomach prolease activity, and the effect that promotes rat gastric secretion to increase is significantly better than other each compatibility groups (P<0.05).
To sum up, the different proportioning groups of medicine of the present invention/health food all have significant promotion intestinal motility, promote the effects such as pepsinia, wherein especially with proportioning group 1(Chinese yam: Fructus Hordei Germinatus: fennel seeds=5:3.33:1, be Chinese yam 15g, Fructus Hordei Germinatus 10g, fennel seeds 3g) effect the most remarkable, can be by promoting mouse small intestine to move, promoting rat gastric secretion, improve the number of ways such as peptic activity of stomach and improve digestive functions, is the optimum dose proportion of medicine/health food of the present invention.
Test example 2 pharmaceutical composition/health food of the present invention improves gastrointestinal function effect and is better than simple
Checking:
1 experiment material
1.1 Experimental agents pharmaceutical composition/health food of the present invention, by Chinese yam 15g, Fructus Hordei Germinatus 10g, fennel seeds 3g(consumption per day) etc. form for primary raw material.Water boiling and extraction, concentrating and being mixed with concentration is that 47g crude drug in whole/100ml medicinal extract sample is standby, is divided into three groups: high dose group, middle dosage group, low dose group.
Chinese yam Zu，You Luzhou Baicaotang Chinese Herbal Pieces Co., Ltd provides.Boiling, decocting liquid concentrates and is mixed with concentration is that 47g crude drug in whole/100ml medicinal extract sample is standby.
Fructus Hordei Germinatus Zu，You Luzhou Baicaotang Chinese Herbal Pieces Co., Ltd provides.Adopt Chinese yam same procedure to process to such an extent that sample is standby.
Fennel seeds Zu，You Luzhou Baicaotang Chinese Herbal Pieces Co., Ltd provides.Adopt Chinese yam same procedure to process to such an extent that sample is standby.
1.2 animal used as test KM mouse, Da Shuo bio tech ltd, Chengdu provides, and body weight 18-22g is male, the animal quality certification number: animal credit number: SCXK(river) 2008-24; SD rat, Chengdu University of Traditional Chinese Medicine's Experimental Animal Center provides, and body weight 140g～160g is male, the animal quality certification number: SCXK(river) 2008-11.
1.3 experiment reagents and instrument electronic balance (one thousandth precision, 0.1g); Loperamide hydrochloride (Xi'an Yang Sen company, lot number: 031014878); Gum arabic, prepared Chinese ink.
2 experimental techniques
2.1 impacts on intestinal motility
96 of male KM mouse, divide 8 groups at random, comprise 6 kinds of different dosing groups, blank group and model control group, 12 of every treated animals.With 10 times (4.7g crude drug/kgBW) of human body consumption per day, per os gives 12 kinds of different given the test agent, and 1 time/d, continuous 15d, blank group and model control group give experimental water by same volume.Give after given the test agent 15d, each is organized mouse fasting and can't help water 16h.After 30min, model control group and each administration group gavage give compound diphenoxylate (5mg/kgBW), and blank group to experimental water.Give after compound diphenoxylate 30min, each administration group contains the prepared Chinese ink (activated carbon powder, 10% gum arabic containing 5%) of corresponding given the test agent, and blank group and model control group give prepared Chinese ink.After giving prepared Chinese ink 25min, disconnected neck is put to death animal, anatomical isolation mesenterium, take out pylorus (upper end) to the little intestinal tube of ileocecus (lower end), be placed in pallet, gently draw intestinal tube to be in line, measure small intestine total length, prepared Chinese ink advances length (pylorus is to prepared Chinese ink forward position), is calculated as follows prepared Chinese ink impelling ratio (P) and prepared Chinese ink propelling rate:
Prepared Chinese ink impelling ratio (P)=prepared Chinese ink advances length (cm)/small intestine total length (cm)
Prepared Chinese ink propelling rate
Adopt SPSS12.0 software to carry out statistical analysis to each proportioning group result and blank group, model control group.
2.2 impacts on digestive enzyme activity
70 of male SD rats, divide 7 groups at random, comprise 6 kinds of administration groups, blank group, 10 of every treated animals, and the difference of the weight of animals should be no more than 10% of average weight.Per os gives different given the test agent, and 1 time/d, continuous 30d, blank group control group gives experimental water by same volume.After last administration, water 24h is can't help in each treated animal fasting, adopts etherization rat pylorus ligature law to collect the gastric juice of discharging in certain hour, gastric juice amount in the analytical unit time.Select internal diameter 1.5mm glass tube, inject Fresh Egg clear, put in hot bath and keep flat and make to take out after protein coagulating, discard alveolate protein pipe, put Refrigerator store, make before use 3cm length.Get the conical flask that gastric juice 1mL puts into 50mL, add 0.05mol/L hydrochloric acid solution 15mL to shake up, put into two of the protein pipe of made fresh.Fill in bottleneck, in 37 ℃ of insulating boxs, hatched 24h, taken out protein pipe, with chi, measured the length (mm) of protein pipe two ends transparent part, with the value of four ends, asked its mean value.Calculate pepsin activity and pepsin discharge rate.
Pepsin activity unit (U/mL)=tetra-end protein pipe transparent part length average
2* 16
Pepsin discharge rate (U/h)=pepsin activity * gastric juice amount per hour
Adopt SPSS12.0 software to carry out statistical analysis to each proportioning group result and blank group, model control group.
3 experimental results
Different groups to the experimental result of mouse small intestine motion effects in Table 3:
The impact of the different groups of table 3 on mouse prepared Chinese ink propelling rate
Note: with model control group comparison, * P<0.05, * * P<0.01; With the comparison of middle dosage group,
△p < 0.05,
△ △p < 0.01.
From table 3, model control group prepared Chinese ink impelling ratio and propelling rate, all significantly lower than blank group (P<0.05), show Constipated mice establishment.Compare with model control group, the high, medium and low dosage group of medicine/health food of the present invention all can significantly promote intestinal motility (P<0.05, P<0.01), wherein high, middle dosage group has utmost point significant difference to the prepared Chinese ink propelling rate of mouse, acts on more obvious.Compare with dosage group in compound of the present invention, other simple groups all have significant difference (P<0.05 to the prepared Chinese ink propelling rate of mouse, P<0.01), show under Isodose condition, compound of the present invention promotes that the effect of intestinal motility is more excellent.
Different groups to the sex experimental result of rat digestive enzyme in Table 4:
The impact of the different groups of table 4 on rat digestive ferment
Note: with the comparison of blank group, * P<0.05, * * P<0.01; With the comparison of middle dosage group,
△p < 0.05,
△ △p < 0.01.
From table 4, compare with blank group, medicine/health food of the present invention is high, in, the rat stomach protease discharge rate of low dose group has significant difference (P<0.05, P<0.01), and in, high dose group utmost point conspicuousness effect (P<0.01), can be significantly or the utmost point significantly improve rat stomach prolease activity, promote rat gastric secretion to increase (P<0.05, P<0.01), illustrate that the present composition is all better than each taste prescription and solely uses, in the present composition, each component has the effect of Synergistic.Compare with dosage group in compound of the present invention, other simple groups, to rat stomach prolease activity, promote rat gastric juice secretion all to have significant difference (P<0.05, P<0.01), show under Isodose condition, compound effect of the present invention is more excellent.
To sum up, medicine/health food provided by the invention can, by promoting intestinal motility, promote gastric secretion, improving the number of ways such as peptic activity of stomach, significantly improve digestive functions.
Claims (8)
1. the food, health products or the pharmaceutical composition that improve digestive functions, is characterized in that: it is the preparation that the raw material by following weight proportion is prepared from: 10～15 parts of Chinese yams, 10～15 parts, Fructus Hordei Germinatus, 3～5 parts of fennel seeds.
2. food according to claim 1, health products or pharmaceutical composition, is characterized in that: it is the preparation that the raw material by following weight proportion is prepared from: 15 parts of Chinese yams, 10 parts, Fructus Hordei Germinatus, 3 parts of fennel seeds.
3. food according to claim 1 and 2, health products or pharmaceutical composition, it is characterized in that: it is by the medicinal powder of each bulk drug, the water of bulk drug, or/and ethanol extract is active component, adds the preparation that auxiliary material conventional in pharmacy or health products or complementary composition are prepared from.
4. according to food, health products or pharmaceutical composition described in claim 1～3 any one, it is characterized in that: described preparation is oral formulations.
5. food according to claim 4, health products or pharmaceutical composition, is characterized in that: described oral formulations is paste, oral liquid, medicinal tea, granule, capsule, pill, tablet or powder.
6. the preparation method of food, health products or pharmaceutical composition described in claim 1～5 any one, is characterized in that: it comprises the steps:
(1) take by weight ratio each bulk drug;
(2) each bulk drug directly pulverized or added water or/and after alcohol extract, add auxiliary material conventional in pharmacy or health products or complementary composition, being prepared into conventional preparation.
7. described in claim 1～5 any one, food, health products or pharmaceutical composition improve the purposes in food, health products or the medicine of digestive functions in preparation.
8. purposes according to claim 7, is characterized in that: described food, health products or medicine are to have the intestinal motility of promotion, gastric secretion, improve food, health products or the medicine of peptic activity of stomach.
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| CN108420066A (en) * | 2017-02-14 | 2018-08-21 | 泸州百草堂健康产品有限公司 | A kind of composition for tonifying spleen and nourishing stomach and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1569118A (en) * | 2004-04-28 | 2005-01-26 | 南京中科生化技术有限公司 | Chinese traditional medicinal formulation for protecting alimentary tract mucosa |
| CN101766765A (en) * | 2008-12-30 | 2010-07-07 | 北京中科仁和科技有限公司 | Granule for treating children indigestion |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1569118A (en) * | 2004-04-28 | 2005-01-26 | 南京中科生化技术有限公司 | Chinese traditional medicinal formulation for protecting alimentary tract mucosa |
| CN101766765A (en) * | 2008-12-30 | 2010-07-07 | 北京中科仁和科技有限公司 | Granule for treating children indigestion |
Non-Patent Citations (1)
| Title |
|---|
| 田琳，等: "调气中药对豚鼠体外胃平滑肌运动的影响", 《中国中西医结合消化杂志》, vol. 15, no. 5, 31 October 2007 (2007-10-31) * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108420066A (en) * | 2017-02-14 | 2018-08-21 | 泸州百草堂健康产品有限公司 | A kind of composition for tonifying spleen and nourishing stomach and preparation method thereof |
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