CN103616910A - Multi-channel fluid automatic control device - Google Patents

Multi-channel fluid automatic control device Download PDF

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Publication number
CN103616910A
CN103616910A CN201310689952.4A CN201310689952A CN103616910A CN 103616910 A CN103616910 A CN 103616910A CN 201310689952 A CN201310689952 A CN 201310689952A CN 103616910 A CN103616910 A CN 103616910A
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China
Prior art keywords
pressure
control
fluid
automaton
hyperchannel
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CN201310689952.4A
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Chinese (zh)
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聂富强
沙俊
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SUZHOU WENHAO CHIP TECHNOLOGY Co Ltd
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SUZHOU WENHAO CHIP TECHNOLOGY Co Ltd
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Priority to CN201310689952.4A priority Critical patent/CN103616910A/en
Publication of CN103616910A publication Critical patent/CN103616910A/en
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Abstract

The invention relates to a multi-channel fluid automatic control device for the fields of biological analysis, chemical analysis, environmental detection, food safety, medical diagnosis, and the like which use fluid control. The multi-channel fluid automatic control device mainly comprises a pressure source (1), a program control device (2), a pressure display device (3), a control program input device (4), a control program display device (5), a pressure regulating device (6), a multi-channel output port (7), a multi-channel output indicating device (8), a standby pressure source interface (9) and a multi-path conversion and control device (10). According to the invention, the pressure source (1) is dispersed to the multi-channel output port (7) through the program control device (2) and outputs pressure according to a preset program set by the control program input device (4), so that the control output of a fluid is realized. The multi-channel fluid automatic control device disclosed by the invention is suitable for automatically controlling the fluid, can realize the complicated programmed control and has the characteristic of automatic and accurate control of the aspects of fluid volume, fluid flow, fluid flow velocity, fluid pressure, and the like.

Description

A kind of hyperchannel microfluid automaton
Technical field
Invention relates to a kind of hyperchannel microfluid automaton, and this device is controlled the complex operations that realizes micro fluid by the robotization to input pressure or flow velocity, belong to micro-total analysis system automation control area.
Background technology
Micro-total analysis system (miniaturized total analysis system, μ TAS) is the multifunction micro determination and analysis system that integrated sample introduction, sample preparation, biochemical reaction, separation, detection are integrated.Micro-fluidic chip (Micro-fluidic chip) is its main building block, there is microminiaturization, robotization, the advantage such as integrated, convenient and quick, in a lot of fields, obtain a wide range of applications fields such as cell biology, analytical chemistry, materialogy, organizational project, environment measuring, food security and medical diagnosis.It is basis that micro-fluidic chip be take analytical chemistry and biological chemistry, utilize the technology (MEMS) of micro electronmechanical processing, at silicon, glass, quartz, frosting, process the microchannel network of 1-500 micron, by complicated design, realize steps such as the sampling of target analytes, dilution, reagent adding, enrichment, extraction, mixing, reaction, separation, detections.In micro-fluidic chip, the type of drive of microfluid mainly contains two kinds of internal drive and external drives, it is driving force that internal drive mainly be take electroosmotic flow, electrophoresis stream and surface tension, by changing driving voltage and material character, controls flow direction and the flow velocity of fluid in the network of microchannel; External drive is mainly syringe pump, peristaltic pump and constant pressure pump.The former cost is high, and design is complicated, needs expensive external main equipment to realize, and the latter only can provide the flow control of pressure source and simple break-make, cannot realize and meet the needs that micro-fluidic chip is controlled complex fluid.
Due to the broad prospect of application of microfluidic chip analysis technology, set up a hyperchannel microfluid automaton that performance is efficient, with low cost, full-automatic, multi-functional, easy and simple to handle, be a technical matters in the urgent need to address.
Summary of the invention
In order to solve the problems of the technologies described above, the object of this invention is to provide hyperchannel microfluid automaton efficiently cheap, full-automatic, multi-functional and easy and simple to handle.
The technical solution adopted in the present invention is: a kind of hyperchannel microfluid automaton, this device comprises pressure source, presetting apparatus, pressure-display device, control program input media, control program display device, pressure adjustment assembly, hyperchannel output port, hyperchannel output indicating device, standby pressure source interface, multi-path conversion and control device.
Further, described hyperchannel microfluid automaton is inputted instruction by control program input media to presetting apparatus, the Output pressure mode in the latter's controlled pressure source, and input process and final instruction can be visual by control program display device; Described pressure source, can also be by accessing with pressure source interface the quantity that external pressure source comes propagation pressure source except the pressure source of this multi-channel fluid automaton self assembling; By described multi-path conversion and control device, pressure source can be distributed to hyperchannel output port artificially, and can pass through the artificial setup control way of output of presetting apparatus; Described pressure adjustment assembly can regulate size and the flow velocity of the input of input pressure source, and can show by pressure-display device size and the flow velocity of pressure source; The way of output of described hyperchannel output port can be passed through hyperchannel output indicating device synchronously visual.
Further, the installation site of described pressure source, presetting apparatus, pressure-display device, control program input media, control program display device, pressure adjustment assembly, hyperchannel output port, hyperchannel output indicating device, standby pressure source interface and multi-path conversion and control device and other servicing units and mode can be all around, upper and lower and internal freedom combination.
Further, described pressure source can be gas, can be also liquid, or while air inclusion and two kinds of pressure sources of liquid.
Further, what described pressure source provided can be both constant pressure, can be also constant flow velocity, or variable pressure or flow velocity.
Further, what described pressure source provided both can malleation, can be also negative pressure.
Further, described pressure source output or the pressure range of input can be 0-1Mpa, and the flow rates of output or input can be 0-1000mL/s.
Further, described presetting apparatus can be both single-chip microcomputer autonomous control system, can be also to control by host computer or computer.
Further, described control program input media both can be inputted the control program of robotization, can be also manual control mode.
Further, described control program input media can be both push button panel, can be also touch panel.
Further, described control program display device can be both non-touch display screen, can be also touch display screen.
Further, described pressure adjustment assembly can be both knob regulative mode, can be also button regulative mode, or touch-screen regulative mode.
Further, described hyperchannel output port can be both push-in, can be also other interface modes such as knob, or buckle-type.
Further, described hyperchannel output port can be the port of independence or one, the port of electronic control element that can be also comprising of independence or one.
Further, described hyperchannel output port can be output gas or liquid, can be also extracting gases or liquid, or has comprised output simultaneously and extracted two kinds of functions.
Further, the quantity of described hyperchannel output port, can be both 1, can be also 2, or a plurality of.
Further, described hyperchannel output indicating device both can synchronously have been indicated the pressure of each port of hyperchannel output port or output or the input state of flow velocity, pressure or the output of flow velocity or the value of input that also can each port of simultaneous display hyperchannel output port.
Further, described multi-path conversion and control device can be both fluid conversion and control element, can be also electric conversion and control element, or had comprised these two kinds conversions and control element simultaneously.
Further, described multi-path conversion and control device can be 1, can be also 2, or a plurality of.
Further, the mode that interconnects of described multi-path conversion and control device can independent assortment.
The invention has the beneficial effects as follows: by the robotization of input pressure or flow velocity is controlled, can realize the complex operations of micro fluid, and device performance of the present invention is efficient, with low cost, full-automatic, multi-functional and easy and simple to handle.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the specific embodiment of the present invention is described further:
Fig. 1 is the structural front view of a kind of hyperchannel microfluid of the present invention automaton;
Fig. 2 utilizes a kind of hyperchannel microfluid of the present invention automaton will realize the micro-fluidic chip of fluid automatic controlling system.
1 pressure source; 2 force control devices; 3 pressure-display devices; 4 control program input medias; 5 control program display device; 6 pressure adjustment assemblys; 7 hyperchannel output ports; 8 hyperchannel output indicating devices; 9 standby pressure source interfaces; 10 multi-path conversion and control device; A micro-fluidic chip; B micro-fluidic chip right side hyperchannel injection port; C micro-fluidic chip right side sample introduction hyperchannel; D micro-fluidic chip left hand polytunnel injection port; E micro-fluidic chip left side sample introduction hyperchannel; F micro-fluidic chip hybrid reaction microchamber; G micro-fluidic chip goes out sample hyperchannel; H micro-fluidic chip outlet.
Embodiment
Below in conjunction with accompanying drawing 1 and 2 pairs of the specific embodiment of the present invention of accompanying drawing, make a detailed explanation.
Embodiment: a kind of hyperchannel microfluid automaton, its structure mainly comprises: pressure source 1, presetting apparatus 2, pressure-display device 3, control program input media 4, control program display device 5, pressure adjustment assembly 6, hyperchannel output port 7, hyperchannel output indicating device 8, standby pressure source interface 9, multi-path conversion and control device 10.
Described device pressure source 1 is input as 0-1Mpa high-pressure air source, and control program input media 4 is inputted instructions to presetting apparatus 2, the Output pressure in the latter's controlled pressure source 1, and input process and final instruction show by control program display device 5; According to the demonstration of pressure-display device 3, by pressure adjustment assembly 6, regulate suitable pressure to input; Multi-path conversion and control device 10, by default control program in presetting apparatus 2, are controlledly distributed to high-pressure air source hyperchannel output port 7; Hyperchannel output port 7 according to the control mode of pre-set programs to conveying high-pressure source of the gas in micro-fluidic chip a.
Whole operating process is done once to detailed step explanation below: at micro-fluidic chip a right side hyperchannel injection port b and left hand polytunnel injection port d, add different reaction reagents in advance; Hyperchannel output port 7 is connected to a right side hyperchannel injection port b and left hand polytunnel injection port d by pre-set programs control mode, open hyperchannel microfluid automaton operation of the present invention, different reaction reagents is by micro-fluidic chip right side hyperchannel c and micro-fluidic chip left hand polytunnel, according to pre-set programs, enter micro-fluidic chip reaction microchamber f, reacted potpourri enters micro-fluidic chip outlet h by micro-fluidic chip sample output passage g, and the robotization that so far completes microfluid in micro-fluidic chip is controlled.

Claims (10)

1. a hyperchannel microfluid automaton, it is characterized in that: presetting apparatus (2) is accepted the Output pressure mode in the input instruction controlled pressure source (1) of control program input media (4), input process and final instruction are by control program display device (5) synchronously visual; Multi-path conversion and control device (10) are accepted the artificial control way of output of setting of presetting apparatus (2), pressure source are distributed to hyperchannel output port (7), by hyperchannel output indicating device (8) synchronously visual; Pressure adjustment assembly (6) regulates size and the flow velocity of input pressure source (1) input, shows size and the flow velocity of pressure source (1) by pressure-display device (3).
2. by a kind of multi-channel fluid automaton claimed in claim 1, it is characterized in that described pressure source (1) can be gas, also can be liquid, or while air inclusion and liquid, constant pressure (0-1Mpa) can be provided, also can be constant flow velocity (0-1000mL/s), or variable pressure or flow velocity.
3. by a kind of multi-channel fluid automaton claimed in claim 1, it is characterized in that described pressure source (1) can provide malleation, also can provide negative pressure.
4. by a kind of multi-channel fluid automaton claimed in claim 1, it is characterized in that described presetting apparatus (2) can be single-chip microcomputer autonomous control system, also can control by host computer or computer.
5. by a kind of multi-channel fluid automaton claimed in claim 1, the control program input media (4) described in it is characterized in that can be inputted the control program of robotization, can be also manual control mode; Can be push button panel, can be also touch panel.
6. by a kind of multi-channel fluid automaton claimed in claim 1, it is characterized in that described control program display device (5) can be non-touch display screen, can be also touch display screen.
7. by a kind of multi-channel fluid automaton claimed in claim 1, it is characterized in that described pressure adjustment assembly (6) can be knob regulative mode, can be also button regulative mode, or touch-screen regulative mode.
8. by a kind of multi-channel fluid automaton claimed in claim 1, it is characterized in that described hyperchannel output port (7) can be push-in, can be also knob, or buckle-type; Can be separate port, can be also one port, or the port that has comprised electronic control element of independence or one; Can export gas or liquid, also can extracting gases or liquid, or comprise output simultaneously and extract two kinds of functions; Can be 1, can be also 2, or a plurality of.
9. by a kind of multi-channel fluid automaton claimed in claim 1, it is characterized in that described hyperchannel output indicating device (8) can synchronously indicate the pressure of each port of hyperchannel output port (7) or output or the input state of flow velocity, pressure or the output of flow velocity or the value of input that also can each port of simultaneous display hyperchannel output port (7).
10. by a kind of multi-channel fluid automaton claimed in claim 1, it is characterized in that described multi-path conversion and control device (10) can be fluid conversion and control element, also can be electric conversion and control element, or these two kinds conversions and control element have been comprised simultaneously, the mode of interconnecting can independent assortment, quantity can be 1, can be also 2, or a plurality of.
CN201310689952.4A 2013-12-17 2013-12-17 Multi-channel fluid automatic control device Pending CN103616910A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104101494A (en) * 2014-07-15 2014-10-15 超达阀门集团股份有限公司 Valve opening and closing cycle life testing system

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CN1727888A (en) * 2005-07-20 2006-02-01 中国科学院上海微系统与信息技术研究所 A kind of mini type electrophoresis detection system of microflow control chip and detection autocontrol method
CN101187669A (en) * 2006-11-22 2008-05-28 柯尼卡美能达医疗印刷器材株式会社 Microchip inspection system and method used in microchip inspection system
US20090325276A1 (en) * 2006-09-27 2009-12-31 Micronics, Inc. Integrated microfluidic assay devices and methods
CN103604936A (en) * 2013-11-08 2014-02-26 苏州汶颢芯片科技有限公司 Automatic control and analysis detector for micro-fluidic chip

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1588088A (en) * 1923-12-27 1926-06-08 Bond Edward Samuel Machine for making wire netting
CN1521499A (en) * 2003-02-12 2004-08-18 财团法人工业技术研究院 Polydirectional logic type microfluid control system and method thereof
CN1727888A (en) * 2005-07-20 2006-02-01 中国科学院上海微系统与信息技术研究所 A kind of mini type electrophoresis detection system of microflow control chip and detection autocontrol method
US20090325276A1 (en) * 2006-09-27 2009-12-31 Micronics, Inc. Integrated microfluidic assay devices and methods
CN101187669A (en) * 2006-11-22 2008-05-28 柯尼卡美能达医疗印刷器材株式会社 Microchip inspection system and method used in microchip inspection system
CN103604936A (en) * 2013-11-08 2014-02-26 苏州汶颢芯片科技有限公司 Automatic control and analysis detector for micro-fluidic chip

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104101494A (en) * 2014-07-15 2014-10-15 超达阀门集团股份有限公司 Valve opening and closing cycle life testing system
CN104101494B (en) * 2014-07-15 2015-08-19 超达阀门集团股份有限公司 A kind of valve opening and closing cycling life test system

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Application publication date: 20140305