CN103383349B - The supervisory system of energy high-quality collection of blood plasma and monitoring method - Google Patents
The supervisory system of energy high-quality collection of blood plasma and monitoring method Download PDFInfo
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- CN103383349B CN103383349B CN201210135316.2A CN201210135316A CN103383349B CN 103383349 B CN103383349 B CN 103383349B CN 201210135316 A CN201210135316 A CN 201210135316A CN 103383349 B CN103383349 B CN 103383349B
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Abstract
The present invention relates to the supervisory system of energy high-quality collection of blood plasma and monitoring method. Technical scheme is as follows: comprise blood inductor block, optoelectronic induction part comprises photoelectric amplifier and fibre-optical probe, photoelectric amplifier can send three primary colours mixed light and be irradiated on tested blood plasma by fibre-optical probe, reflected light is transmitted to photoelectric amplifier by fibre-optical probe and calculates, be according to diffuse-reflectance light voluntarily analyzing and processing chromatic aberration and according to light source changing conditions implement chromatic aberration saltus step, calculation result by TTL level feed-back to master control system; By the wavelength of spectrum, it is three primary colours red, green, blue, is also judged blood plasma and red corpuscle by wavelength exactly. To accept reflected light, carry out the change of analytical wavelengths, thus judge the red cell volume of medium to judge in blood plasma. Useful effect is as follows: solve blood plasma separation big by external interference, and stability is poor, easily cause and red corpuscle is monitored failure problem, has also stopped thrombocyte, the collection of red corpuscle unwanted contributions.
Description
Technical field:
The present invention relates to the monitoring method in the medicine equipment of a kind of sampled plasma and collection, particularly relate to supervisory system and the monitoring method of energy high-quality collection of blood plasma.
Background technology:
Function singleness is there is in current domestic centrifugal type blood composition separating machine in blood ingredient monitoring, blood inductor block (visible ray correlation type) is generally adopted to identify that the blood plasma dim light of night changes the monitoring of red corpuscle, big by external interference, stability is poor, easily cause and monitor unsuccessfully to red corpuscle, directly affects plasma collection quality.
Summary of the invention:
Goal of the invention:
In order to provide one dual to monitor, it is to increase monitoring effect and precision, judge supervisory system and the monitoring method of the energy high-quality collection of blood plasma of blood plasma segregation ratio in advance.
In order to reach as above object, the present invention takes following technical scheme: comprise blood inductor block, it is characterized in that: also comprise optoelectronic induction part, described optoelectronic induction part comprises photoelectric amplifier and fibre-optical probe, the function that photoelectric amplifier can realize is as follows: sends three primary colours mixed light and is irradiated on tested blood plasma by fibre-optical probe, reflected light is transmitted to photoelectric amplifier by fibre-optical probe and calculates, computation process be according to diffuse-reflectance light voluntarily analyzing and processing chromatic aberration and according to light source changing conditions implement chromatic aberration saltus step, calculation result passes through TTL level feed-back to master control system, three primary colours mixed optical path can calculate the difference of its composition according to reflected light photoelectric amplifier after being irradiated on blood plasma or blood, by wavelength, judge the color change state of analyte, and determine the content of red corpuscle.
The further technical scheme of the present invention is: described master control system gathers the monitoring data of blood inductor block simultaneously, calculates single loop slurry-outlet quantity in conjunction with two groups of data.
The further technical scheme of the present invention is: described photo-sensor solves because Centrifuge Cup material transparency, liquid-covered bubble disturb the impact caused by simple subprogram external calibration.
The further technical scheme of the present invention is: by the wavelength of spectrum, is three primary colours red, green, blue, is judged blood plasma and red corpuscle by wavelength, to accept reflected light, carrys out the change of analytical wavelengths, thus judges the red cell volume of medium to judge in blood plasma.
The method of the monitoring of energy high-quality collection of blood plasma, it is characterised in that: comprise following steps:
A. automatically calibrate according to Centrifuge Cup material transparency, liquid-covered bubble regime change photo-sensor;
B. device as above is taked to be directed at tested blood plasma or blood sends three primary colours mixed light and analyzed by reflected light, analyze the difference of blood plasma in Centrifuge Cup, blood ingredient, according to diffuse-reflectance light voluntarily analyzing and processing chromatic aberration and according to light source changing conditions implement chromatic aberration saltus step, method of calculation pass through wavelength, judge the color change state of analyte, and determine the difference of composition;
D. undertaken can be calculated blood plasma segregation ratio by analytical results; Analytical results can be transferred to master control system simultaneously; Master control system gathers the monitoring data of blood inductor block simultaneously, calculates single loop slurry-outlet quantity in conjunction with two groups of data.
Adopt the present invention of as above technical scheme, there is following useful effect: realize not only solving blood plasma separation by several step function above and be subject to external interference big, stability is poor, easily cause and red corpuscle is monitored failure problem, also stopped thrombocyte, the collection of red corpuscle unwanted contributions, also made equipment reach the object of high quality blood plasma separation.
Embodiment:
Being described by embodiments of the invention below, embodiment is not construed as limiting the invention:
1, photo-sensor and blood inductor block realize blood plasma separation of double being monitored.
2, photo-sensor adopts three primary colours mixed optical path detection principle can precisely identify the difference of blood plasma in Centrifuge Cup, blood ingredient.
3, separate cup inner blood separating medium is directly carried out detection monitoring by photo-sensor.
4, photo-sensor judges in advance according to blood plasma segregation ratio in Centrifuge Cup.
5, photo-sensor is solved because of Centrifuge Cup material transparency, liquid-covered bubble interference problem by simple subprogram external calibration.
6, PCMO2 software system can according to photo-sensor and blood inductor block 2 monitoring point intellectual analysis single loop slurry-outlet quantities, plasma collection quality height.
Detection thing interface is calibrated automatically, avoids the impact of material properties difference. Specific embodiment of the invention is not caused restriction by the kind of transparent material.
About parts:
1, photoelectricity module is divided into: photoelectric amplifier, fibre-optical probe two discrete parts compositions.
2, photoelectric amplifier sends three primary colours mixed light and is irradiated to testee on the surface by probe.
3, testee reflected light is transmitted to photoelectric amplifier device by fibre-optical probe and carries out sampling processing.
4, photoelectric amplifier according to diffuse-reflectance light voluntarily analyzing and processing chromatic aberration and according to light source changing conditions implement chromatic aberration saltus step, by TTL level feed-back to master control system.
5, photoelectric amplifier sensitivity, luminous Gain Automatic adjustment do not need artificial participation.
6, different measured medium pattern can manually be preset.
7, the concrete external calibration function of photoelectric amplifier, external calibration has equipment master control system automatically to complete, it is not necessary to manually participate in.
More than show and describe the ultimate principle of the present invention, the advantage of main characteristic sum the present invention.The technician of the industry should understand; the present invention is not restricted to the described embodiments; the principle that the present invention is just described described in above-described embodiment and specification sheets; the present invention also has various changes and modifications without departing from the spirit and scope of the present invention, and these changes and improvements all fall in the claimed scope of the invention. The claimed scope of the present invention by appending claims and etc. jljl define.
Claims (3)
1. the supervisory system of energy high-quality collection of blood plasma, comprise blood inductor block, it is characterized in that: also comprise optoelectronic induction part, described optoelectronic induction part comprises photoelectric amplifier and fibre-optical probe, the function that photoelectric amplifier can realize is as follows: sends three primary colours mixed light and is irradiated on tested blood plasma by fibre-optical probe, reflected light is transmitted to photoelectric amplifier by fibre-optical probe and calculates, computation process be according to diffuse-reflectance light voluntarily analyzing and processing chromatic aberration and according to light source changing conditions implement chromatic aberration saltus step, calculation result passes through TTL level feed-back to master control system, three primary colours mixed optical path can calculate the difference of its composition according to reflected light photoelectric amplifier after being irradiated on blood plasma or blood, by wavelength, judges the color change state of analyte, so that it is determined that the content of red corpuscle,
Described master control system gathers the monitoring data of blood inductor block simultaneously, calculates single loop slurry-outlet quantity in conjunction with two groups of data.
2. the supervisory system of energy high-quality collection of blood plasma as claimed in claim 1, it is characterised in that: described optoelectronic induction part solves because Centrifuge Cup material transparency, liquid-covered bubble disturb the impact caused by simple subprogram external calibration.
3. the method for the monitoring of energy high-quality collection of blood plasma, it is characterised in that: by the wavelength of spectrum, it is three primary colours red, green, blue, is judged blood plasma and red corpuscle by wavelength, to accept reflected light, carry out the change of analytical wavelengths, so that it is determined that the content of red corpuscle;
Comprise following steps:
A. automatically calibrate according to Centrifuge Cup material transparency, liquid-covered bubble regime change optoelectronic induction part;
B. take as claim 1-2 arbitrarily as described in supervisory system be directed at tested blood plasma or blood sends three primary colours mixed light and analyzed by reflected light, analyze the difference of blood plasma in Centrifuge Cup, blood ingredient, according to diffuse-reflectance light voluntarily analyzing and processing chromatic aberration and according to light source changing conditions implement chromatic aberration saltus step, method of calculation pass through wavelength, judge the color change state of analyte, and determine the difference of composition;
C. undertaken can be calculated blood plasma segregation ratio by analytical results; Analytical results can be transferred to master control system simultaneously; Master control system gathers the monitoring data of blood inductor block simultaneously, calculates single loop slurry-outlet quantity in conjunction with two groups of data.
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US4202625A (en) * | 1978-08-18 | 1980-05-13 | Ortho Diagnostics, Inc. | Method and apparatus for discriminating red blood cells from platelets |
CN1200657A (en) * | 1995-10-23 | 1998-12-02 | 斯托迈奇克公司 | Method and apparatus for reflected imaging analysis |
CN1809739A (en) * | 2003-07-02 | 2006-07-26 | 甘布罗公司 | Monitoring and control system for blood processing |
CN101236158A (en) * | 2007-01-29 | 2008-08-06 | 深圳迈瑞生物医疗电子股份有限公司 | Reticular cell detection method and detection device |
CN101915741A (en) * | 2010-08-03 | 2010-12-15 | 宁波大学 | Portable hemoglobin solution measurement system and measurement method thereof |
CN102016577A (en) * | 2008-05-09 | 2011-04-13 | 希森美康株式会社 | Blood analyzer, blood analysis method and hemolytic agent |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH0618522A (en) * | 1992-07-02 | 1994-01-25 | Hitachi Ltd | Method for detecting hemolytic component in blood |
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2012
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Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4202625A (en) * | 1978-08-18 | 1980-05-13 | Ortho Diagnostics, Inc. | Method and apparatus for discriminating red blood cells from platelets |
CN1200657A (en) * | 1995-10-23 | 1998-12-02 | 斯托迈奇克公司 | Method and apparatus for reflected imaging analysis |
CN1809739A (en) * | 2003-07-02 | 2006-07-26 | 甘布罗公司 | Monitoring and control system for blood processing |
CN101236158A (en) * | 2007-01-29 | 2008-08-06 | 深圳迈瑞生物医疗电子股份有限公司 | Reticular cell detection method and detection device |
CN102016577A (en) * | 2008-05-09 | 2011-04-13 | 希森美康株式会社 | Blood analyzer, blood analysis method and hemolytic agent |
CN101915741A (en) * | 2010-08-03 | 2010-12-15 | 宁波大学 | Portable hemoglobin solution measurement system and measurement method thereof |
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