CN103267867B - Fully-automatic chemiluminescent immunoassay analyzer - Google Patents
Fully-automatic chemiluminescent immunoassay analyzer Download PDFInfo
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- CN103267867B CN103267867B CN201310167162.XA CN201310167162A CN103267867B CN 103267867 B CN103267867 B CN 103267867B CN 201310167162 A CN201310167162 A CN 201310167162A CN 103267867 B CN103267867 B CN 103267867B
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Abstract
The invention relates to a fully-automatic chemiluminescent immunoassay analyzer. The fully-automatic chemiluminescent immunoassay analyzer comprises a frame and a control system, a sample zone, a lath feeding system, an incubation zone and a lath detecting system are sequentially arranged on the frame from the left to the right, a fluid path system is arranged below or at the right side of the incubation zone, a reagent zone is arranged below the incubation zone and below or at the right side of the lath detecting system, a sample arm is arranged at the left side of the frame, a reagent arm is arranged at the right side of the frame, a first push rod arm is arranged above the lath feeding system on the frame, a second push rod arm is arranged in the incubation zone, and the lath feeding system, the incubation zone, the lath detecting system, the fluid path system, the sample arm, the reagent arm, the first push rod arm and the second push rod arm are respectively electrically connected with the control system. The fully-automatic chemiluminescent immunoassay analyzer has the advantages of simple structure, convenient operation, high automation degree, and supporting of the non-shutdown loading.
Description
Technical field
The present invention relates to a kind of Full-automatic chemiluminescence immunoassay analysis meter.
Background technology
Thereby chemical illumination immunity analysis instrument is human body to be carried out to the medical laboratory instrument of immunoassay by detecting patients serum.Quantitative patients serum and horseradish peroxidase (HRP) are joined to solid-phase coating to be had in the White-opalescent microwell plate of antibody, antibody specific binding on testing molecule in serum and the bond of horseradish peroxidase and solid phase carrier, the unreacted free composition of separating, washing, then, add liquid of the luminous end, the free energy that utilizes chemical reaction to discharge excites intermediate, from ground state, gets back to excited state, and energy discharges with the form of photon.But, existing Full-automatic chemiluminescence immunoassay analysis meter is all the faint light energy sending for reading 96 or 48 hole microwell plates in the market, for measuring the concentration of certain antibody of patients serum's sample or antigen, so-called 96 or 48 hole microwell plates are on plank, to comprise 96 or 48 reaction cup, patients serum's sample that each need to detect is placed in a reaction cup, the sample size detecting when needs only has several or need to use equally a monoblock 96 or 48 hole microwell plates tens time, therefore causes a large amount of wastes; On the other hand, current existing Full-automatic chemiluminescence immunoassay analysis meter generally once can only detect a microwell plate, and second microwell plate need to be put into detector again and detect after first detection completes, therefore, the speed detecting is unhappy, and staff's detection efficiency is not high; 96 or 48 microwell plate is longer in the required time of first hole of application of sample to last hole, therefore the consistance of result is had a certain impact; The structure of microwell plate cannot solve the problem of hole interdigit light cross pollution completely.
Summary of the invention
The invention provides a kind of simple in structure, easy to operate, automaticity is high, support not shut down a kind of Full-automatic chemiluminescence immunoassay analysis meter of loading.
The present invention is achieved through the following technical solutions:
A kind of Full-automatic chemiluminescence immunoassay analysis meter, comprise support body and control system, on described support body, be provided with successively from left to right sample area, lath feed system, incubation district and lath detection system, below or the right side in described incubation district are provided with liquid-way system, the below in described incubation district, below or the right side of described lath detection system are provided with reagent area, described support body left side is provided with sample arm, right side is provided with reagent arm, on described support body, be positioned at described lath feed system top and be provided with the first pusher arms, be positioned at inside, described incubation district and be provided with the second pusher arms, described lath feed system, incubation district, lath detection system, liquid-way system, sample arm, reagent arm, the first pusher arms and the second pusher arms are electrically connected to described control system respectively.
Described lath feed system comprises lath frame, enters panel assembly, plate taking device and application of sample snubber assembly, describedly enter panel assembly, plate taking device and application of sample snubber assembly and be all fixed on described support body, described plate taking device enters panel assembly rear described in being located at, described application of sample snubber assembly is located between described plate taking device and described incubation district, described in enter panel assembly, plate taking device and application of sample snubber assembly and be electrically connected to described control system respectively; Describedly enter panel assembly and comprise shell, stack gate, the first motor and the first slide mechanism, after user is placed on described lath frame by lath, from stack gate, put into the bottom of described shell, under the drive of the first motor, by the first slide mechanism, lath frame is lifted to the top of shell; Described plate taking device comprises handgrip, the second motor and the second slide mechanism, and described handgrip takes out lath frame under the drive of the second motor and the second slide mechanism in shell; Described application of sample snubber assembly comprises application of sample buffer zone base, the 3rd motor and the 3rd slide mechanism, lath on described lath frame moves on the base of described application of sample buffer zone by the first pusher arms, moving linearly under the drive of the 3rd motor and the 3rd slide mechanism, and carry out application of sample by sample arm.
Described incubation district comprises lucifuge shell, incubation district base, the 4th motor, the 4th slide mechanism and the second pusher arms, it is inner that described incubation district base, the 4th slide mechanism and the second pusher arms are all located at described lucifuge shell, lath after application of sample is moved on incubation district base from application of sample buffer zone base, under the drive of the 4th motor and the 4th slide mechanism, shake, described the second pusher arms is provided with sensitization liquid sample needle, described liquid-way system comprises sensitization liquid and cleaning fluid, by ram pump, is connected with described sensitization liquid phase.
Described lath detection system comprises detection module, sliding block, lath driver module and lath active module, and described detection module is positioned at described lath active module top, and described sliding block slides and is located at described lath driver module top.
Described lath active module comprises lath chute, Qianmen and back door, described lath is located in described lath chute, one end of described lath chute is located at described Qianmen by Qianmen resetting-mechanism, the bottom of the described lath chute other end is provided with fluting, described fluting top is located at by back door resetting-mechanism in described back door, described Qianmen is provided with jack, and described back door is provided with slot.
Described sliding block comprises fixed head, lath fixation fork, direct current generator and leading screw, described lath fixation fork is slidably connected by slide rail and described fixed head, described direct current generator is fixed on fixed head, and be provided with driving gear at output terminal, described leading screw one end is connected with described lath fixation fork, the other end is provided with follower gear, described driving gear and follower gear are meshed, one side of described lath fixation fork is provided with Qianmen inserted link, described Qianmen inserted link inserts in the jack at described Qianmen in the time need to driving Qianmen, the lower surface of described lath fixation fork is provided with back door inserted link, described back door inserted link inserts in the slot at described back door in the time need to driving back door, described lath fixation fork is provided with some inserted sheets, described lath chute wall is provided with groove, described inserted sheet inserts between the gap on described lath through described groove.
Described Full-automatic chemiluminescence immunoassay analysis meter also comprises dilution vibration district, and described dilution vibration district is fixed on described support body, and between described sample area and lath feed system.
Described lath frame lower surface is provided with two blocks, and the two ends of described block change into fillet.
On described application of sample buffer zone base and incubation district base, be equipped with clamp clip, described lath chute is provided with clamp clip, all by screw, fixes.
Described support body outside is provided with housing.
The beneficial effect that the present invention brings is:
In the present invention, loading is not shut down in described Full-automatic chemiluminescence immunoassay analysis meter support, be that user can add from entering panel assembly the lath frame of having placed lath continuously in non-stop-machine situation, by plate taking device, take out again, and at application of sample snubber assembly place application of sample, after application of sample, lath immigration incubation district carries out incubation processing, the lath of lath immigration afterwards detection system detects and the lath after having detected is discharged in pail for used dressings, above whole process can be carried out continuously under non-stop-machine state, so just improved detection efficiency, and guaranteed the accuracy detecting, on the other hand, 96 or 48 hole microwell plates are resolved into single lath and enter detection, more flexible than using 96 or 48 hole microwell plates to detect, and cost-saving, when single lath enters flowing water detection, short to the time interval of last reaction cup application of sample or reagent adding from first reaction cup application of sample or reagent adding, and then testing result is more accurate, inserted sheet on described lath fixation fork inserts between the gap on described lath through described groove, can reduce the hole interdigit light cross pollution of adjacent two reaction cup, and on the other hand, described inserted sheet can play the effect that drives lath to move.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the present invention is described in further detail.
Fig. 1 is the structural representation of Full-automatic chemiluminescence immunoassay analysis meter of the present invention.
Fig. 2 is the structural representation of lath feed system of the present invention.
Fig. 3 is the structural representation of lath frame of the present invention.
Fig. 4 is the structural representation in incubation of the present invention district.
Fig. 5 is the structural representation of lath detection system of the present invention.
Fig. 6 is the structural representation of lath active module of the present invention.
Fig. 7 is the structural representation of sliding block of the present invention.
Fig. 8 is the structural representation of lath fixation fork of the present invention.
The label that in figure, component names is corresponding is as follows:
1, support body; 2, control system; 3, sample area; 4, lath feed system; 5, incubation district; 6, lath detection system; 7, reagent area; 8, sample arm; 9, reagent arm; 10, the first pusher arms; 11, the second pusher arms; 12, lath frame; 13, shell; 14, stack gate; 15, the first motor; 16, the first slide mechanism; 17, lath; 18, handgrip; 19, the second motor; 20, the second slide mechanism; 21, application of sample buffer zone base; 22, the 3rd motor; 23, the 3rd slide mechanism; 24, incubation district base; 25, the 4th motor; 26, the 4th slide mechanism; 27, sensitization liquid sample needle; 28, sensitization liquid; 29, cleaning fluid; 30, ram pump; 31, detection module; 32, sliding block; 33, lath driver module; 34, lath active module; 35, lath chute; 36, Qianmen; 37, back door; 38, Qianmen resetting-mechanism; 39, fluting; 40, back door resetting-mechanism; 41, jack; 42, slot; 43, fixed head; 44, lath fixation fork; 45, direct current generator; 46, leading screw; 47, slide rail; 48, driving gear; 49, follower gear; 50, Qianmen inserted link; 51, back door inserted link; 52, inserted sheet; 53, groove; 54, dilution vibration district; 55, block; 56, clamp clip; 57, screw.
Embodiment
Below in conjunction with drawings and Examples, the present invention is described in further detail:
Embodiment as Full-automatic chemiluminescence immunoassay analysis meter of the present invention, as shown in Figure 1, comprise support body 1 and control system 2, on described support body 1, be provided with successively from left to right sample area 3, lath feed system 4, incubation district 5 and lath detection system 6, the below in described incubation district 5 is provided with liquid-way system, the below in described incubation district 5 is provided with reagent area 7, described support body 1 left side is provided with sample arm 8, right side is provided with reagent arm 9, on described support body 1, be positioned at described lath feed system 4 tops and be provided with the first pusher arms 10, be positioned at 5 inside, described incubation district and be provided with the second pusher arms 11, described lath feed system 4, incubation district 5, lath detection system 6, liquid-way system, sample arm 8, reagent arm 9, the first pusher arms 10 and the second pusher arms 11 are electrically connected to described control system 2 respectively.
In the present embodiment, as shown in Figures 2 and 3, described lath feed system 4 comprises lath frame 12, enters panel assembly, plate taking device and application of sample snubber assembly, describedly enter panel assembly, plate taking device and application of sample snubber assembly and be all fixed on described support body 1, described plate taking device enters panel assembly rear described in being located at, described application of sample snubber assembly is located between described plate taking device and described incubation district 5, described in enter panel assembly, plate taking device and application of sample snubber assembly and be electrically connected to described control system 2 respectively; Describedly enter panel assembly and comprise shell 13, stack gate 14, the first motor 15 and the first slide mechanism 16, after user is placed on described lath frame 12 by lath 17, from stack gate 14, put into the bottom of described shell 13, under the drive of the first motor 15, by the first slide mechanism 16, lath frame 12 is lifted to the top of shell 13; Described plate taking device comprises handgrip 18, the second motor 19 and the second slide mechanism 20, described handgrip 18 under the drive of the second motor 19 and the second slide mechanism 20 by lath frame 12 from the interior taking-up of shell 13; Described application of sample snubber assembly comprises application of sample buffer zone base 21, the 3rd motor 22 and the 3rd slide mechanism 23, lath 17 on described lath frame 12 moves on described application of sample buffer zone base 21 by the first pusher arms 10, moving linearly under the drive of the 3rd motor 22 and the 3rd slide mechanism 23, and carry out application of sample by sample arm 8.
In the present embodiment, as shown in Figure 4, described incubation district 5 comprises lucifuge shell (not shown), incubation district base 24, the 4th motor 25, the 4th slide mechanism 26 and the second pusher arms 11, described incubation district base 24, it is inner that the 4th slide mechanism 26 and the second pusher arms 11 are all located at described lucifuge shell, lath after application of sample 17 is moved on incubation district base 24 from application of sample buffer zone base 21, under the drive of the 4th motor 25 and the 4th slide mechanism 26, shake, described the second pusher arms 11 is provided with sensitization liquid sample needle 27, described liquid-way system comprises sensitization liquid 28 and cleaning fluid 29, by ram pump 30, be connected with described sensitization liquid 28.
In the present embodiment, as shown in Figure 5, described lath detection system 6 comprises detection module 31, sliding block 32, lath driver module 33 and lath active module 34, described detection module 31 is positioned at described lath active module 34 tops, and described sliding block 32 slides and is located at described lath driver module 33 tops.
In the present embodiment, as shown in Figure 6, described lath active module 34 comprises lath chute 35,36He back door, Qianmen 37, described lath 17 is located in described lath chute 35, one end of described lath chute 35 is located at described Qianmen 36 by Qianmen resetting-mechanism 38, the bottom of described lath chute 35 other ends is provided with fluting 39, and described fluting 39 tops are located at by back door resetting-mechanism 40 in described back door 37, described Qianmen 36 is provided with jack 41, and described back door 37 is provided with slot 42.
In the present embodiment, as shown in Figure 7 and Figure 8, described sliding block 32 comprises fixed head 43, lath fixation fork 44, direct current generator 45 and leading screw 46, described lath fixation fork 44 is slidably connected by slide rail 47 and described fixed head 43, described direct current generator 45 is fixed on fixed head 43, and be provided with driving gear 48 at output terminal, described leading screw 46 one end are connected with described lath fixation fork 44, the other end is provided with follower gear 49, described driving gear 48 and follower gear 49 are meshed, one side of described lath fixation fork 44 is provided with Qianmen inserted link 50, described Qianmen inserted link 50 inserts in the jack 41 at described Qianmen 36 in the time need to driving Qianmen 36, the lower surface of described lath fixation fork 44 is provided with back door inserted link 51, described back door inserted link 51 inserts in the slot 42 at described back door 37 in the time need to driving back door 37, described lath fixation fork 44 is provided with seven inserted sheets 52, described lath chute 35 sidewalls are provided with groove 53, between the gap that described inserted sheet 52 inserts on described lath 17 through described groove 53.
In the present embodiment, described Full-automatic chemiluminescence immunoassay analysis meter also comprises dilution vibration district 54, and described dilution vibration district 54 is fixed on described support body 1, and between described sample area 3 and lath feed system 4.
In the present embodiment, described lath frame 12 lower surfaces are provided with two blocks 55, and the two ends of described block 55 change into fillet.
In the present embodiment, on base 21He incubation district, described application of sample buffer zone base 24, be equipped with clamp clip 56, described lath chute 35 is provided with clamp clip 56, all fixing by screw 57.
In the present embodiment, described support body 1 outside is provided with housing (not shown).
Claims (8)
1. a Full-automatic chemiluminescence immunoassay analysis meter, it is characterized in that comprising support body and control system, on described support body, be provided with successively from left to right sample area, lath feed system, incubation district, dilution vibration district and lath detection system, below or the right side in described incubation district are provided with liquid-way system, the below in described incubation district, below or the right side of described lath detection system are provided with reagent area, described support body left side is provided with sample arm, right side is provided with reagent arm, on described support body, be positioned at described lath feed system top and be provided with the first pusher arms, be positioned at inside, described incubation district and be provided with the second pusher arms, described lath feed system, incubation district, lath detection system, liquid-way system, sample arm, reagent arm, the first pusher arms and the second pusher arms are electrically connected to described control system respectively, described dilution vibration district is fixed on described support body, and between described sample area and lath feed system, described lath detection system comprises detection module, sliding block, lath driver module and lath active module, described sliding block comprises fixed head, lath fixation fork, direct current generator and leading screw, described lath fixation fork is slidably connected by slide rail and described fixed head, described direct current generator is fixed on fixed head, and be provided with driving gear at output terminal, described leading screw one end is connected with described lath fixation fork, the other end is provided with follower gear, described driving gear and follower gear are meshed, one side of described lath fixation fork is provided with Qianmen inserted link, described Qianmen inserted link inserts in the jack at described Qianmen in the time need to driving Qianmen, the lower surface of described lath fixation fork is provided with back door inserted link, described back door inserted link inserts in the slot at described back door in the time need to driving back door, described lath fixation fork is provided with some inserted sheets, described lath chute wall is provided with groove, described inserted sheet inserts between the gap on described lath through described groove.
2. Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 1, it is characterized in that described lath feed system comprises lath frame, enters panel assembly, plate taking device and application of sample snubber assembly, describedly enter panel assembly, plate taking device and application of sample snubber assembly and be all fixed on described support body, described plate taking device enters panel assembly rear described in being located at, described application of sample snubber assembly is located between described plate taking device and described incubation district, described in enter panel assembly, plate taking device and application of sample snubber assembly and be electrically connected to described control system respectively; Describedly enter panel assembly and comprise shell, stack gate, the first motor and the first slide mechanism, after user is placed on described lath frame by lath, from stack gate, put into the bottom of described shell, under the drive of the first motor, by the first slide mechanism, lath frame is lifted to the top of shell; Described plate taking device comprises handgrip, the second motor and the second slide mechanism, and described handgrip takes out lath frame under the drive of the second motor and the second slide mechanism in shell; Described application of sample snubber assembly comprises application of sample buffer zone base, the 3rd motor and the 3rd slide mechanism, lath on described lath frame moves on the base of described application of sample buffer zone by the first pusher arms, moving linearly under the drive of the 3rd motor and the 3rd slide mechanism, and carry out application of sample by sample arm.
3. Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 2, it is characterized in that described incubation district comprises lucifuge shell, incubation district base, the 4th motor, the 4th slide mechanism and the second pusher arms, described incubation district base, it is inner that the 4th slide mechanism and the second pusher arms are all located at described lucifuge shell, lath after application of sample is moved on incubation district base from application of sample buffer zone base, under the drive of the 4th motor and the 4th slide mechanism, shake, described the second pusher arms is provided with sensitization liquid sample needle, described liquid-way system comprises sensitization liquid and cleaning fluid, by ram pump, be connected with described sensitization liquid phase.
4. Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 3, is characterized in that described detection module is positioned at described lath active module top, and described sliding block slides and is located at described lath driver module top.
5. Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 4, it is characterized in that described lath active module comprises lath chute, Qianmen and back door, described lath is located in described lath chute, one end of described lath chute is located at described Qianmen by Qianmen resetting-mechanism, the bottom of the described lath chute other end is provided with fluting, described fluting top is located at by back door resetting-mechanism in described back door, and described Qianmen is provided with jack, and described back door is provided with slot.
6. the Full-automatic chemiluminescence immunoassay analysis meter as described in claim 2-5 any one, is characterized in that described lath frame lower surface is provided with two blocks, and the two ends of described block change into fillet.
7. Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 6, is characterized in that being equipped with clamp clip on described application of sample buffer zone base and incubation district base, and described lath chute is provided with clamp clip, all by screw, fixes.
8. Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 7, is characterized in that described support body outside is provided with housing.
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| CN201310167162.XA CN103267867B (en) | 2013-05-09 | 2013-05-09 | Fully-automatic chemiluminescent immunoassay analyzer |
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| CN201310167162.XA CN103267867B (en) | 2013-05-09 | 2013-05-09 | Fully-automatic chemiluminescent immunoassay analyzer |
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| CN103267867B true CN103267867B (en) | 2014-09-10 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105319379B (en) * | 2014-05-21 | 2017-02-22 | 凯和生物科技(上海)有限公司 | Full-automatic analyzer for immunity |
| CN106199025B (en) * | 2016-01-18 | 2018-03-20 | 深圳雷杜生命科学股份有限公司 | Full-automatic chemiluminescence immunoassay analysis meter |
| CN106980024A (en) * | 2017-03-28 | 2017-07-25 | 杭州凯坤科技有限公司 | A kind of full-automatic light-induced chemiluminescent detector |
| CN107831326A (en) * | 2017-10-20 | 2018-03-23 | 厦门市波生生物技术有限公司 | Full-automatic chemiluminescence immunoassay analysis meter |
| CN107831322A (en) * | 2017-12-08 | 2018-03-23 | 郑州科蒂亚生物技术有限公司 | A kind of Full-automatic chemiluminescence immunoassay analysis meter device |
| CN110161258B (en) * | 2018-02-11 | 2021-01-01 | 博阳生物科技（上海）有限公司 | Full-automatic light-activated chemiluminescence detector |
| CN110412258A (en) * | 2018-04-28 | 2019-11-05 | 上海索昕生物科技有限公司 | Full-automatic light-induced chemiluminescent detector |
| CN110470658B (en) * | 2018-05-11 | 2022-04-29 | 科美博阳诊断技术(上海)有限公司 | Control method of chemiluminescence analyzer and application thereof |
| CN110470854A (en) * | 2018-05-11 | 2019-11-19 | 博阳生物科技（上海）有限公司 | Automatic lmunoassays analyzer |
| CN108507848A (en) * | 2018-07-05 | 2018-09-07 | 嘉兴凯实生物科技有限公司 | A kind of incubation module |
| CN109030808A (en) * | 2018-10-24 | 2018-12-18 | 嘉兴凯实生物科技有限公司 | A kind of improved automatic chemical illumination immunity analysis instrument |
| CN109507438B (en) * | 2018-11-08 | 2022-06-14 | 迪瑞医疗科技股份有限公司 | Linear incubation groove and full-automatic biochemical analyzer thereof |
| CN109738256B (en) * | 2019-02-27 | 2024-03-08 | 苏州鑫点石精密机械制造有限公司 | Food detection pretreatment device and pretreatment method |
| CN109775373A (en) * | 2019-03-18 | 2019-05-21 | 北京爱博生生物技术有限公司 | A kind of full-automatic microwell plate board-washing work station of goods yard formula |
| CN112433063B (en) * | 2020-11-09 | 2021-07-09 | 昭衍(北京)医药科技有限公司 | Full-automatic chemiluminescence immunoassay technical platform |
| CN116148459B (en) * | 2023-01-09 | 2024-02-23 | 浙江宝太智能科技有限公司 | Reading compensation method for chemiluminescent reader |
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| US7842504B2 (en) * | 2004-04-02 | 2010-11-30 | Siemens Healthcare Diagnostics Inc. | Method for increasing throughput in an automatic clinical analyzer by duplicating reagent resources |
| CN102183639B (en) * | 2011-03-14 | 2013-06-05 | 哈尔滨工业大学（威海） | Full-automatic chemiluminescence immunity analyzer |
| CN202421193U (en) * | 2011-11-15 | 2012-09-05 | 北京勤邦生物技术有限公司 | Automatic reaction cup feeding and abandoning device |
| CN102520201B (en) * | 2011-12-31 | 2013-05-15 | 重庆州泰生物科技有限公司 | Automatic chemoluminescence immunity detecting system |
| CN102998473B (en) * | 2012-12-19 | 2014-06-11 | 北京利德曼生化股份有限公司 | Full-automatic chemiluminescence immune analyzer |
| CN203191380U (en) * | 2013-05-09 | 2013-09-11 | 嘉兴凯实生物科技有限公司 | Full-automatic chemiluminescence immunoassay analyzer |
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Denomination of invention: Fully-automatic chemiluminescent immunoassay analyzer Effective date of registration: 20151225 Granted publication date: 20140910 Pledgee: Bank of Hangzhou, Limited by Share Ltd, Jiaxing branch Pledgor: Jiaxing Quest Life Science Co., Ltd. Registration number: 2015990001162 |
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Address after: 314000 floor 3, building 1, floor 2-3, building 2, No. 3535, linggongtang Road, Nanhu District, Jiaxing City, Zhejiang Province Patentee after: Jiaxing Kaishi Biotechnology Co.,Ltd. Address before: 3 / F, building 6, 3339 linggongtang Road, Jiaxing City, Zhejiang Province Patentee before: JIAXING QUEST BIOTECHNOLOGY Co.,Ltd. |