CN102920437B - Close-distance imaging device and using method thereof - Google Patents
Close-distance imaging device and using method thereof Download PDFInfo
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- CN102920437B CN102920437B CN201210422507.7A CN201210422507A CN102920437B CN 102920437 B CN102920437 B CN 102920437B CN 201210422507 A CN201210422507 A CN 201210422507A CN 102920437 B CN102920437 B CN 102920437B
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- 238000003384 imaging method Methods 0.000 title claims abstract description 50
- 238000000034 method Methods 0.000 title claims abstract description 16
- 238000001514 detection method Methods 0.000 claims description 17
- 238000005286 illumination Methods 0.000 claims description 13
- 230000003287 optical effect Effects 0.000 claims description 13
- 238000012360 testing method Methods 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 10
- 238000007654 immersion Methods 0.000 claims description 9
- 230000003667 anti-reflective effect Effects 0.000 claims description 5
- 238000010276 construction Methods 0.000 claims description 4
- 230000021615 conjugation Effects 0.000 claims description 3
- 230000001678 irradiating effect Effects 0.000 abstract description 15
- 238000012014 optical coherence tomography Methods 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 230000001427 coherent effect Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
Abstract
The invention discloses a close-distance imaging device and a using method thereof, wherein the close-distance imaging device comprises a shell and an imaging unit, wherein at least one irradiating unit and a signal receiving unit are arranged in the shell, the irradiating unit comprises a shiner and an irradiating lens, the shiner and the irradiating lens are relatively arranged, the signal receiving unit comprises a sensor and a signal receiving lens, the sensor and the signal receiving lens are relatively arranged, the sensor is connected with the imaging unit, and the imaging unit is used for outputting image information of an object to be detected. The close-distance imaging device also comprises a relay lens, wherein the irradiating lens and the signal receiving lens are arranged on the same side of the relay lens, the other side of the relay lens faces to the outside of the shell, the relay lens is used for delivering irradiating light emitted by the irradiating unit to the object to be detected, and delivering a signal reflected by the object to be detected to the signal receiving unit.
Description
Technical field
The present invention relates to one closely imaging device and using method thereof, this closely imaging device be applied to medical field.
Background technology
Micro-medical imaging is with a long history, be detect, observe, measure human organ organize indispensable instrument.These image-forming informations are of value to medical diagnosis and treatment.Conventional microscope needs sampling, fixing, and dehydration, the processes such as section carry out long time treatment sample.Therefore, Real Time Observation biological tissue and cellularity have a great attraction to medical circle.In recent years, Optical coherence tomography (OCT) utilizes coherent light, and such as laser and Michelson's interferometer equipment carrys out transdermal.The image obtained by this method is depth plane.Another kind method, Laser Scanning Confocal Microscope, utilizes identical light path, and throw light on and receive the optical signal sent in biological tissue, final imaging is transverse plane image in biological tissue.A point-like light is used for illumination specific target sample, therefore can eliminate conventional microscope strain light and other side effect.Device as OCT and Laser Scanning Confocal Microscope is usually heavier, and limits single wavelength if laser is as light source.
But optical signal sends and receives is all by beam splitter, this structure is not suitable for use in the microstructure of medical treatment or other application usually, because beam splitter needs right angle to form usually, causes taking up room larger.Wherein beam splitter makes the light signal reflected can only irradiate towards sample direction, optical signal from sample can arrive optical sensor by transmitted beam separator, but beam splitter is normally effective for specific wavelength, result is that this device only to work under single or a few wavelength case.
Summary of the invention
The object of the invention is to provide a kind of closely imaging device that can work under multi-wavelength and using method thereof.
Closely imaging device of the present invention, comprise shell and image-generating unit, at least one illumination unit and a signal receiving unit is provided with in shell, illumination unit comprises luminous body and irradiates lens, luminous body is oppositely arranged with irradiation lens, signal receiving unit comprises sensor and Signal reception lens, sensor and Signal reception lens are oppositely arranged, sensor is connected with image-generating unit, image-generating unit is used for the image information of output detections thing, described closely imaging device also comprises relay lens, irradiation lens and Signal reception lens are placed in the same side of relay lens, relay lens opposite side is towards outside shell, the irradiation light that relay lens is used for illumination unit to send delivers to detection thing, and the flashlight detecting thing reflection is delivered to signal receiving unit.
As shown in Figure 1, in the prior art, need to adopt beam splitter to realize the correct transmission of optical signal, but the optical signal of beam splitter only for specific wavelength is effective, thus causes existing imaging device can only work under single or a few wavelength case; In addition, adopt beam splitter usually to need illumination unit and signal receiving unit at right angles to arrange, cause taking up room of equipment comparatively large, be not suitable for for armarium or other micromodule equipments.
The present invention adopts relay lens to substitute beam splitter, still achieves the correct transmission of optical signal, and relay lens is effective to the optical signal of multi-wavelength, makes the present invention can be applicable to multiple working condition; In addition, adopt after relay lens, illumination unit and signal receiving unit, without the need to rectangular layout, make the structure of equipment can be less, compacter, more can be applicable to armarium or other micromodule equipments.
Preferably, described irradiation lens and Signal reception lens are arranged side by side,
Described irradiation lens side is relative with luminous body, and opposite side is relative with relay lens;
Described Signal reception lens side is relative with sensor, and opposite side is relative with relay lens.
Preferably, described multiple irradiation lens arrangement is a shadow surface, and multiple Signal reception lens arrangement is a Signal reception face, and shadow surface, Signal reception face are arranged with the detection faces conjugation detecting thing.
Preferably, described irradiation lens and Signal reception lens are arranged around the same side of relay lens,
Described irradiation lens side is relative with luminous body, and opposite side is relative with relay lens;
Described Signal reception lens side is relative with sensor, and opposite side is relative with relay lens.
Preferably, described luminous body is irradiate the adjustable luminous body of optical wavelength.
The irradiation optical wavelength sent due to luminous body is adjustable, makes closely imaging device can regulate according to detecting thing the wavelength irradiating light, to obtain the image information detecting thing more accurately.
Preferably, described luminous body comprises LCD and backlight, and LCD side is relative with irradiation lens, and opposite side is relative with backlight.
Preferably, described backlight is LED.
Preferably, described luminous body is monochromatic LED, multi-colored led, ultrared ray generator, ultraviolet light generator or laser generator.
Preferably, described relay lens surface is provided with anti-reflective film.
Because optical signal can produce reflection after relay lens, thus affect the accuracy of closely imaging device acquisition testing object image information, so arrange anti-reflective film on relay lens surface, decrease the direct reflection of optical signal, thus improve the accuracy of closely imaging device acquisition testing object image information.
Preferably, described relay lens is in sphere or ellipsoid shaped.
Preferably, described shell is waterproof construction.
Because the shell of closely imaging device adopts waterproof construction, make closely imaging device can carry out Scanning Detction to the detection thing in liquid.
Preferably, described image-generating unit comprises display, and image-generating unit is by the image of display output detections thing.
The using method of closely imaging device of the present invention,
(1) closely imaging device is used to scan detection thing, to obtain the image information detecting each test point of thing;
(2) image information detecting each test point of thing is delivered to image-generating unit;
(3) image information is analyzed with image-generating unit, and the image of output detections thing.
Preferably, closely imaging device is used to scan each test point detecting thing according to priority.
According to priority each test point detecting thing is scanned, make each image information relatedness high, facilitate the analyzing and processing of image.
Preferably, detect thing with immersion liquid submergence, closely imaging device is placed in immersion liquid the scanning of detection thing.
Preferably, send according to closely imaging device the immersion liquid that the wavelength that irradiates light and the optocoupler coefficient detected between thing select to match.
Select different immersion liquid according to different situations, can ensure that closely imaging device can obtain the image information detecting thing exactly.
Accompanying drawing explanation
Fig. 1 is the structural representation of prior art;
Fig. 2 is the structural representation of the first embodiment of the present invention;
Fig. 3 is the structural representation of the second embodiment of the present invention.
Detailed description of the invention
The first embodiment of the present invention as shown in Figure 2, comprise shell and image-generating unit, shell is set to waterproof construction, Signal reception lens 30 are provided with in shell, irradiate lens 20, relay lens 10, sensor 31, LCD21 and LED22, wherein Signal reception lens 30, irradiate lens 20 and relay lens 10 conjugation layout, Signal reception lens 30 and irradiation lens 20 are arranged side by side, Signal reception lens 30 and irradiation lens 20 are placed in the same side of relay lens 10, Signal reception lens 30 are parallel with the back side of relay lens 10 relative with the front irradiating lens 20, the back side of Signal reception lens 30 is parallel relative with sensor 31, the back side irradiating lens 20 is parallel relative with the front of LCD21, the back side of LCD is parallel relative with the front of LED, the front of relay lens 10 is towards outside shell, and relay lens 10 is in sphere, the surface of relay lens 10 is also coated with anti-reflective film 11, described image-generating unit is connected with sensor 31, and wherein, image-generating unit includes display.
Using method of the present invention is as follows, first LED22 sends illumination light, illumination light is delivered to LCD21 and is then produced irradiation light, irradiate light and deliver to relay lens 10 through irradiating lens 20, then irradiate light and deliver to detection thing through relay lens 10 again, irradiation light after testing thing is reflected as flashlight, flashlight delivers to Signal reception lens 30 through relay lens 10, then flashlight delivers to sensor 31 through Signal reception lens 30 again, sensor 31 transfers Received signal strength light to image information, and image information is delivered to image-generating unit, reduced the direct reflection of irradiating light and flashlight by the anti-reflective film 11 on relay lens 10 in whole process, the accuracy of image information is gathered to improve closely imaging device, repeat above-mentioned steps, according to priority image information collecting is carried out to each test point detecting thing, till the image information collecting that will detect all test points of thing is complete, now image-generating unit carries out analyzing and processing to the image information of all receptions, and detects the image of thing by display display.
The accuracy of image information is gathered in order to improve closely imaging device further, the immersion liquid that the wavelength that irradiates light and the optocoupler coefficient detected between thing select to match should be sent according to closely imaging device, and detect thing with immersion liquid submergence, then repeat the image information that above-mentioned steps just can obtain detection thing exactly; Again because the duty of control LCD can regulate the wavelength irradiating light, make closely imaging device can regulate according to detecting thing the wavelength irradiating light, with obtain more accurately detect thing image information (when equipment irradiates the adjustable function of light without the need to arranging, also can select LCD21, monochromatic LED, multi-colored led, ultrared ray generator, ultraviolet light generator or laser generator etc. replace, irradiate light directly to send).
The second embodiment of the present invention as shown in Figure 3, its structure is substantially identical with the first embodiment of the present invention with using method, its difference is: Signal reception lens 30 are not arranged side by side with irradiation lens 20, both arrange around the back side of relay lens 10, make Signal reception lens 30 be splayed with the arrangement of irradiation lens 20.
Wherein, above for Signal reception lens 30, the definition of irradiating the positive back side of lens 20 and relay lens 10, only in order to more clearly make an explanation to technical scheme, technical scheme do not formed and limiting; In addition, multiple signal receiving unit (signal receiving unit is made up of sensor 31 and Signal reception lens 30) and illumination unit (illumination unit is made up of LCD21, LED22 and irradiation lens 20) can also be set according to actual needs.
The protection domain being also considered as patent that the basis of above embodiment is improved.
Claims (15)
1. a closely imaging device, for Real Time Observation biological tissue and cellularity, comprise shell and image-generating unit, at least one illumination unit and multiple signal receiving unit is provided with in shell, illumination unit comprises luminous body and irradiates lens, luminous body is oppositely arranged with irradiation lens, signal receiving unit comprises sensor and Signal reception lens, sensor and Signal reception lens are oppositely arranged, sensor is connected with image-generating unit, image-generating unit is used for the image information of output detections thing, it is characterized in that: described closely imaging device also comprises relay lens, irradiation lens and Signal reception lens are placed in the same side of relay lens, relay lens opposite side is towards outside shell, the irradiation light that relay lens is used for illumination unit to send delivers to detection thing, and the flashlight detecting thing reflection is delivered to signal receiving unit, described luminous body is irradiate the adjustable luminous body of optical wavelength.
2. closely imaging device according to claim 1, is characterized in that: described irradiation lens and Signal reception lens are arranged side by side,
Described irradiation lens side is relative with luminous body, and opposite side is relative with relay lens;
Described Signal reception lens side is relative with sensor, and opposite side is relative with relay lens.
3. closely imaging device according to claim 2, it is characterized in that: described irradiation lens have multiple, multiple irradiation lens arrangement is a shadow surface, and multiple Signal reception lens arrangement is a Signal reception face, and shadow surface, Signal reception face are arranged with the detection faces conjugation detecting thing.
4. closely imaging device according to claim 1, is characterized in that: described irradiation lens and Signal reception lens are arranged around the same side of relay lens,
Described irradiation lens side is relative with luminous body, and opposite side is relative with relay lens;
Described Signal reception lens side is relative with sensor, and opposite side is relative with relay lens.
5. closely imaging device according to claim 1, is characterized in that: described luminous body comprises LCD and backlight, and LCD side is relative with irradiation lens, and opposite side is relative with backlight.
6. closely imaging device according to claim 5, is characterized in that: described backlight is LED.
7. closely imaging device according to claim 1, is characterized in that: described luminous body is monochromatic LED, multi-colored led, ultrared ray generator, ultraviolet light generator or laser generator.
8. closely imaging device according to claim 1, is characterized in that: described relay lens surface is provided with anti-reflective film.
9. closely imaging device according to claim 1, is characterized in that: described relay lens is in sphere or ellipsoid shaped.
10. closely imaging device according to claim 1, is characterized in that: described shell is waterproof construction.
11. closely imaging devices according to claim 1, is characterized in that: described image-generating unit comprises display, and image-generating unit is by the image of display output detections thing.
The using method of closely imaging device described in 12. 1 kinds of claim 1, is characterized in that:
(1) closely imaging device is used to scan detection thing, to obtain the image information detecting each test point of thing;
(2) image information detecting each test point of thing is delivered to image-generating unit;
(3) image information is analyzed with image-generating unit, and the image of output detections thing.
13., according to the using method of closely imaging device described in claim 12, is characterized in that: use closely imaging device according to priority to each test point scanning detecting thing.
14. according to the using method of closely imaging device described in claim 12, and it is characterized in that: detect thing with immersion liquid submergence, closely imaging device is placed in immersion liquid the scanning of detection thing.
15., according to the using method of closely imaging device described in claim 14, is characterized in that: send according to closely imaging device the immersion liquid that the wavelength that irradiates light and the optocoupler coefficient detected between thing select to match.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210422507.7A CN102920437B (en) | 2012-10-29 | 2012-10-29 | Close-distance imaging device and using method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210422507.7A CN102920437B (en) | 2012-10-29 | 2012-10-29 | Close-distance imaging device and using method thereof |
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| Publication Number | Publication Date |
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| CN102920437A CN102920437A (en) | 2013-02-13 |
| CN102920437B true CN102920437B (en) | 2015-03-11 |
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| CN201210422507.7A Active CN102920437B (en) | 2012-10-29 | 2012-10-29 | Close-distance imaging device and using method thereof |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4866258A (en) * | 1987-07-10 | 1989-09-12 | Matsushita Electric Industrial Co., Ltd. | Optical pattern detecting apparatus |
| CN1673943A (en) * | 2004-03-22 | 2005-09-28 | 安捷伦科技公司 | Contaminant-resistant optical mouse and cradle |
| CN1729932A (en) * | 2005-09-01 | 2006-02-08 | 北京光电技术研究所 | Endoscope lighting arrangement |
| CN1964231A (en) * | 2005-11-09 | 2007-05-16 | 鸿富锦精密工业（深圳）有限公司 | A multifunctional adapter |
| CN101288105A (en) * | 2005-10-11 | 2008-10-15 | 普莱姆传感有限公司 | Method and system for object reconstruction |
| CN102105780A (en) * | 2008-07-24 | 2011-06-22 | 麻省理工学院 | Systems and methods for imaging using absorption |
| CN202908679U (en) * | 2012-10-29 | 2013-05-01 | 广州市盛光微电子有限公司 | Close range imaging device |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3559341B2 (en) * | 1995-02-15 | 2004-09-02 | ペンタックス株式会社 | Stereoscopic endoscope |
-
2012
- 2012-10-29 CN CN201210422507.7A patent/CN102920437B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4866258A (en) * | 1987-07-10 | 1989-09-12 | Matsushita Electric Industrial Co., Ltd. | Optical pattern detecting apparatus |
| CN1673943A (en) * | 2004-03-22 | 2005-09-28 | 安捷伦科技公司 | Contaminant-resistant optical mouse and cradle |
| CN1729932A (en) * | 2005-09-01 | 2006-02-08 | 北京光电技术研究所 | Endoscope lighting arrangement |
| CN101288105A (en) * | 2005-10-11 | 2008-10-15 | 普莱姆传感有限公司 | Method and system for object reconstruction |
| CN1964231A (en) * | 2005-11-09 | 2007-05-16 | 鸿富锦精密工业（深圳）有限公司 | A multifunctional adapter |
| CN102105780A (en) * | 2008-07-24 | 2011-06-22 | 麻省理工学院 | Systems and methods for imaging using absorption |
| CN202908679U (en) * | 2012-10-29 | 2013-05-01 | 广州市盛光微电子有限公司 | Close range imaging device |
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Effective date of registration: 20211123 Address after: 510700 No. 308, building G2, South China new material innovation park, No. 31, Kefeng Road, Science City, high tech Industrial Development Zone, Guangzhou, Guangdong Patentee after: COMPUTATIONAL IMAGING MICROSYSTEMS Inc. Address before: C1-1106, innovation building, No. 182, science Avenue, Science City, Guangzhou, Guangdong 510663 Patentee before: COMPUTATIONAL IMAGING MICROSYSTEMS Inc. Patentee before: GUANGZHOU BLOOMBASE INFORMATION TECHNOLOGY CO.,LTD. |
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Effective date of registration: 20231219 Granted publication date: 20150311 |