CN102735829B - Blood gas analyzer and using method thereof - Google Patents

Blood gas analyzer and using method thereof Download PDF

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Publication number
CN102735829B
CN102735829B CN 201210252942 CN201210252942A CN102735829B CN 102735829 B CN102735829 B CN 102735829B CN 201210252942 CN201210252942 CN 201210252942 CN 201210252942 A CN201210252942 A CN 201210252942A CN 102735829 B CN102735829 B CN 102735829B
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China
Prior art keywords
pump housing
solenoid valve
reagent
liquid
connects
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CN 201210252942
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CN102735829A (en
Inventor
侯兴凯
姚新宁
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Shenzhen Kang Li Biological Medicine Co., Ltd.
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MEIZHOU KANGLI HIGH-TECH Co Ltd
SHENZHEN MAIDICONG MEDICAL ELECTRONIC CO Ltd
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Application filed by MEIZHOU KANGLI HIGH-TECH Co Ltd, SHENZHEN MAIDICONG MEDICAL ELECTRONIC CO Ltd filed Critical MEIZHOU KANGLI HIGH-TECH Co Ltd
Priority to CN 201210252942 priority Critical patent/CN102735829B/en
Publication of CN102735829A publication Critical patent/CN102735829A/en
Priority to PCT/CN2013/074830 priority patent/WO2014015691A1/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4925Blood measuring blood gas content, e.g. O2, CO2, HCO3
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers

Abstract

The invention discloses a blood gas analyzer which comprises a needle valve arranged in a sampling frame, a sample box connected with the needle valve, a first pump body connected with the sample box, a waste liquid bag connected with the first pump body, a liquid detector connected with the needle valve and the second pump body, a third electromagnetic valve connected with the liquid detector, a first electromagnetic valve connected with the second pump body and a third pump body connected with the needle valve and the waste liquid bag, wherein in the sample box, one end of a front detector is connected with the needle valve, while the other end of the front detector is sequentially connected with a detection membrane pipe and a rear detector, and the rear detector is connected with the first pump body; the above parts are connected through flow pipes; a memory is connected with the detection membrane pipe through an electrode; and the first electromagnetic valve and the second electromagnetic valve are both provided with air inlets. According to the invention, a gas-liquid mixed calibration method in the prior art is replaced by liquid calibration, so that the method is more convenient for use, and faults caused by that liquid enters an air path are avoided, the fault probability is reduced, and the reliability of the analyzer is improved.

Description

A kind of blood gas analyzer and using method thereof
Technical field
The present invention relates to the medical science field tests, relate in particular to a kind of blood gas analyzer and using method thereof.
Background technology
Iontophoresis electrode was measured the passage calibration after the PCO2 of existing homemade blood gas analyzer, the calibration of PO2 electrode all adopted the different high gas of gas mixing ratio and two kinds of pressure gass of low gas through decompression, insulation, humidifying, and remaining electrode adopts the normal fluid calibration.In this calibration mode, stream divides gas circuit and liquid road, the control of gas-liquid infall is comparatively complicated, particularly under situation about breaking down, calibration solution or cleaning fluid enter gas circuit and very easily damage solenoid valve, in addition, because the existence of gas cylinder, instrument is not easy to make the portable or hand propelled of removable use, makes the standard fate defeated inconvenient; Because calibrating gas is pressure gas, gas cylinder is bigger again, is not easy to transportation and use, and ability was available after pressure gas will pass through decompression, insulation, humidifying, and use is comparatively loaded down with trivial details.Therefore be badly in need of a kind of easy to use, reliable quality qi and blood analyser.
Summary of the invention
The purpose of this invention is to provide a kind of blood gas analyzer and using method thereof, the method that replaces gas of the prior art and liquid hybrid scaling by the liquid calibration, use more convenient, avoid entering the fault that gas circuit produces because of liquid, reduce the probability that breaks down, thereby improved the reliability of instrument.
Technical scheme of the present invention is: a kind of blood gas analyzer comprises: the needle-valve that places sampling stand, the sales kit (SK) that connects described needle-valve, first pump housing that connects described sales kit (SK), the waste fluid bag that connects described first pump housing, the detector of liquid that connects described needle-valve and second pump housing, the 4th reagent bag that connects described second pump housing by second solenoid valve, the 3rd solenoid valve that connects described detector of liquid, first solenoid valve that connects this second pump housing, the first reagent bag that connects described detector of liquid by the 6th solenoid valve, the second reagent bag that connects described detector of liquid by the 5th solenoid valve, connect the 3rd reagent bag of described detector of liquid and the 3rd pump housing that connects needle-valve and waste fluid bag by the 4th solenoid valve; In the sales kit (SK), an end of preceding detecting device connects needle-valve, and the other end connects detection film pipe and back detecting device successively, and back detecting device connects first pump housing; All connect by flow channel tube between aforementioned each parts; Storer connects detection film pipe by electrode; In above-mentioned each reagent bag different liquid is housed, on first solenoid valve and the 3rd solenoid valve air intake opening is arranged, when detector of liquid detects liquid, the closed electromagnetic valve of having opened that is used for extracting liquid, the 3rd solenoid valve is opened, and air substitutes liquid and enters flow channel tube, in the balance flow channel tube and the air pressure of space outerpace, make the liquid in the flow channel tube enter the detection of detection film pipe smoothly, saved liquid simultaneously; When second solenoid valve is opened the extraction cleaning fluid, open first solenoid valve, air is entered in the flow channel tube, air and cleaning fluid mix, and form the cleaning fluid of segmentation in flow channel tube, clean more thorough.
Wherein, the 3rd solenoid valve, the 4th solenoid valve, the 5th solenoid valve and the 6th solenoid valve are set up in parallel, connect the flow channel tube between second pump housing and the detector of liquid in order successively, the most close described second pump housing of described the 3rd solenoid valve, solenoid valve is swift in response, switch is flexible, and control is automatically used easily blood gas analyzer.In the first reagent bag first reagent is arranged, in the second reagent bag second reagent is arranged, in first reagent and second reagent, the numerical value of target to be measured was determined before detecting, be known, the numerical value of twice detection is contrasted with two described definite values respectively, if the numerical value that detects is identical with determined value, just illustrate that blood gas analyzer is accurately, can continue to use, if the numerical value that detects is different with determined value, just illustrate that blood gas analyzer is inaccurate, need to adjust blood gas analyzer.In the described storer that the data of first reagent, second reagent and sample detection are all preserved, the data that the user obtains according to test sample are judged and are analyzed, and carry out subsequent operation.In the technical program, only utilize liquid, without gas, therefore without gas cylinder, make things convenient for transportation and the movement of instrument; Only utilize liquid, use also very simply, the trouble of avoided reducing pressure because using gas to need, insulation, humidifying bringing; Avoid having reduced the probability that breaks down because liquid enters the fault that gas circuit produces, thus the reliability of raising instrument.
Further, in the described needle-valve main channel is arranged, first thief hatch and second thief hatch are arranged on the main channel, described first thief hatch connects first passage, and described second thief hatch connects second channel; First reagent, second reagent, protein liquid removal and cleaning fluid enter main channel in the needle-valve by first passage, and first thief hatch in the main channel enters follow-up flow channel tube; When cleaning stream, the cleaning fluid that enters the main channel is divided into two parts, a part enters flow channel tube from first thief hatch, clean in the sales kit (SK) and follow-up stream, enter waste fluid bag at last, another part enters second channel from second thief hatch, extracted out by the 3rd pump housing, enter waste fluid bag at last, the setting of each passage in the needle-valve, the needs that satisfied blood gas analyzer calibration, deproteinized, sampling and cleaned stream, easy to use, avoid having reduced the probability that breaks down because liquid enters the fault that gas circuit produces, thus the reliability of raising instrument.
Further, described first passage connects detector of liquid, be convenient to first reagent, second reagent, protein liquid removal and cleaning fluid and enter main channel in the needle-valve by flow channel tube, described second channel connects the 3rd pump housing by flow channel tube, be convenient to cleaning fluid smoothly by the 3rd pump housing, enter waste fluid bag, thus the convenient stream that cleans.
Further, described blood gas analyzer also comprises the sample collector, this sample collector inserts second thief hatch, sampling needle inserts in the sample collector by the main channel, sample in the draw samples collector, after extraction finished, sampling needle was extracted, the sample collector is also extracted from second thief hatch, and is easy to use.
Further, sampling needle one end inserts in the sample collector by the main channel, detecting device before the other end connects, this sampling needle front end has pin hole, under the effect of first pump housing, the examination sampling needle is extracted the sample in the sample collector out by the pin hole of sidewall, and sample enters described test membrane pipe by preceding detecting device, be convenient to detect, easy to use.
The present invention also provides a kind of using method of blood gas analyzer, comprises the steps:
S1, determine first standard value: open the 6th solenoid valve, first pump housing extracts first reagent in the first reagent bag by flow channel tube; When detector of liquid detects first reagent, close the 6th solenoid valve, open the 3rd solenoid valve, first reagent enters and detects in the film pipe; When the back detecting device detected first reagent, first pump housing stopped operating, and closes the 3rd solenoid valve, and electrode begins test, and the data of test are kept in the storer, as first standard value; Open the 3rd solenoid valve then, first pump housing is with in the first reagent suction waste fluid bag in the stream;
S2, determine second standard value: open the 5th solenoid valve, first pump housing extracts second reagent in the second reagent bag by flow channel tube; When detector of liquid detects second reagent, close the 5th solenoid valve, open the 3rd solenoid valve, second reagent enters and detects in the film pipe; When the back detecting device detected second reagent, first pump housing stopped operating, and electrode begins test, and the data of test are kept in the storer, as second standard value; Open the 3rd solenoid valve then, first pump housing is with in the second reagent suction waste fluid bag in the stream;
S3, deproteinized: open the 4th solenoid valve, first pump housing extracts protein liquid removal in the 3rd reagent bag by flow channel tube; When detector of liquid detected protein liquid removal, described first pump housing continued to be rotated counterclockwise, and closes the 4th solenoid valve then, opens the 3rd solenoid valve, and protein liquid removal enters and detects in the film pipe; When the back detecting device detected protein liquid removal, first pump housing was rotated further, and when protein liquid removal begins to enter waste fluid bag, closes the 3rd solenoid valve, and blood protein residual in protein liquid removal and the stream is fully reacted.At last, first pump housing rotates, in the deproteinized waste liquid suction waste fluid bag in the flow channel tube;
S4, sampling: sampling needle inserts in the sample, and first pump housing rotates counterclockwise, draw samples; Sampling needle is extracted out from sample then, first pump housing is extracted into the sample in the stream and detects in the film pipe through preceding detecting device, sample detecting device before out-of-date constantly detects, after sample passes through preceding detecting device, first pump housing stops operating, and the electrode pair sample detects, and testing result is kept in the storer, first pump rotates, and the sample in the stream is arranged in the waste fluid bag; And
S5, clean stream: the first solenoid valve pause switch, open second solenoid valve, second pump housing is extracted into main channel in the needle-valve by flow channel tube with the cleaning fluid in the 4th reagent bag; First solenoid valve often changes into to be opened, and closes second solenoid valve, and first pump housing is evacuated to waste fluid bag through first thief hatch, sales kit (SK) successively with a part of cleaning fluid that second pump housing pushes the main channel; Simultaneously the 3rd pump housing is shifted second pump housing onto in the main channel of needle-valve and another part cleaning fluid of overflowing to second thief hatch is evacuated to waste fluid bag; Second pump housing rotates continuously, and till detector of liquid detected less than cleaning fluid, first pump housing and the 3rd pump housing stopped operating after the cleaning fluid in the stream all is extracted into waste fluid bag.
Wherein, in the first reagent bag first reagent is housed, in the second reagent bag second reagent is housed, in the 3rd reagent bag protein liquid removal is housed, in the 4th reagent bag cleaning fluid is housed; The 3rd solenoid valve, the 4th solenoid valve, the 5th solenoid valve and the 6th solenoid valve are set up in parallel, connect the flow channel tube between second pump housing and the detector of liquid in order successively, the most close described second pump housing of described the 3rd solenoid valve, solenoid valve is swift in response, switch is flexible, automatically control is used easily blood gas analyzer.In first reagent and second reagent, the numerical value of target to be measured was determined before detecting, be known, the numerical value of twice detection is contrasted with two described definite values respectively, if the numerical value that detects is identical with determined value, just illustrate that blood gas analyzer is accurately, can continue to use, if the numerical value that detects is different with determined value, just illustrate that blood gas analyzer is inaccurate, need to adjust blood gas analyzer.In the described storer that the data of first reagent, second reagent and sample detection are all preserved, the data that the user obtains according to test sample are judged and are analyzed, and carry out subsequent operation.In the technical program, only utilize liquid, without gas, therefore without gas cylinder, make things convenient for transportation and the movement of instrument; Only utilize liquid, use also very simply, the trouble of avoided reducing pressure because using gas to need, insulation, humidifying bringing; Avoid having reduced the probability that breaks down because liquid enters the fault that gas circuit produces, thus the reliability of raising instrument.
Further, among the described step S1, the pin hole of sampling needle is positioned at first thief hatch, and first reagent first passage of flowing through enters the sampling needle from pin hole; Among the described step S2, the pin hole of sampling needle is positioned at first thief hatch, and second reagent first passage of flowing through enters the sampling needle from pin hole.Among step S1 and the S2, sampling needle is positioned at first thief hatch, the liquid of being convenient to enter first thief hatch enters the follow-up stream from sampling needle, easy to use, simultaneously, only detect with liquid, avoided entering the fault that gas circuit produces because of liquid, reduce the probability that breaks down, thereby improved the reliability of instrument.
Further, among the step S4, the bottleneck of sample collector inserts in second thief hatch, sampling needle passes the main channel and inserts in the sample collector, by the sample in the pin hole draw samples collector, extracted sample after, extract sampling needle out, carry out subsequent operation, easy to use.
Beneficial effect of the present invention: replace the method for gas of the prior art and liquid hybrid scaling by liquid calibration, uses more conveniently, avoid having reduced the probability that breaks down because liquid enters the fault that gas circuit produces, thus the reliability of raising instrument.
Description of drawings
Fig. 1 is the structural representation of an embodiment of the present invention;
Fig. 2 is the longitudinal sectional drawing of needle-valve in the one embodiment of the invention;
Fig. 3 be in the one embodiment of the invention when sampling needle-valve longitudinal sectional drawing.
Mark among the figure: 1-sampling stand; The 101-needle-valve; The 102-main channel; The 103-first passage; The 104-second channel; 105-first thief hatch; 106-second thief hatch; The 107-sampling needle; The 108-pin hole; 109-sample collector; The 2-sales kit (SK); Detecting device before the 201-; 202-detects the film pipe; Detecting device behind the 203-; The 204-electrode; The 205-storer; The 3-flow channel tube; 4-first pump housing; 5-second pump housing; 6-the 3rd pump housing; The 7-waste fluid bag; 8-first solenoid valve; 9-second solenoid valve; 10-the 4th reagent bag; 11-the 3rd solenoid valve; 12-the 4th solenoid valve; 13-the 3rd reagent bag; 14-the 5th solenoid valve; The 15-second reagent bag; 16-the 6th solenoid valve; The 17-first reagent bag; The 18-detector of liquid.
Embodiment
Below in conjunction with accompanying drawing, more excellent embodiment of the present invention is described in further detail:
Embodiment 1, referring to Fig. 1, a kind of blood gas analyzer comprises: the needle-valve 101 that places sampling stand 1, the sales kit (SK) 2 that connects described needle-valve 101, first pump housing 4 that connects described sales kit (SK) 2, the waste fluid bag 7 that connects described first pump housing 4, the detector of liquid 18 that connects described needle-valve 101 and second pump housing 5, the 4th reagent bag 10 that connects described second pump housing 5 by second solenoid valve 9, the 3rd solenoid valve 11 that connects described detector of liquid 18, first solenoid valve 8 that connects this second pump housing 5, the first reagent bag 17 that connects described detector of liquid 18 by the 6th solenoid valve 16, the second reagent bag 15 that connects described detector of liquid 18 by the 5th solenoid valve 14, connect the 3rd reagent bag 13 of described detector of liquid 18 and the 3rd pump housing 6 that connects needle-valve 101 and waste fluid bag 7 by the 4th solenoid valve 12; In the sales kit (SK) 2, an end of preceding detecting device 201 connects needle-valve 101, and the other end connects detection film pipe 202 and back detecting device 203 successively, and back detecting device 203 connects first pump housing 4; All passing through flow channel tube 3 between aforementioned each parts connects; Storer 205 connects detection film pipe by electrode 204; In above-mentioned each reagent bag different liquid is housed, on first solenoid valve 8 and the 3rd solenoid valve 11 air intake opening is arranged, when detector of liquid 18 detects liquid, the closed electromagnetic valve of having opened that is used for extracting liquid, the 3rd solenoid valve 11 is opened, and air substitutes liquid and enters flow channel tube 3, in the balance flow channel tube 3 and the air pressure of space outerpace, make the liquid in the flow channel tube 3 enter 202 detections of detection film pipe smoothly, saved liquid simultaneously; When second solenoid valve 9 is opened the extraction cleaning fluid, open first solenoid valve 8, air is entered in the flow channel tube 3, air and cleaning fluid mix, and form the cleaning fluid of segmentation in flow channel tube 3, clean more thorough.
Wherein, the 3rd solenoid valve 11, the 4th solenoid valve 12, the 5th solenoid valve 14 and the 6th solenoid valve 16 are set up in parallel, connect the flow channel tube 3 between second pump housing 5 and the detector of liquid 18 in order successively, described the 3rd solenoid valve 11 the most close described second pump housings 5, solenoid valve is swift in response, switch is flexible, and control is automatically used easily blood gas analyzer.In the first reagent bag 17 first reagent is arranged, in the second reagent bag 15 second reagent is arranged, in first reagent and second reagent, the numerical value of target to be measured was determined before detecting, be known, the numerical value of twice detection is contrasted with two described definite values respectively, if the numerical value that detects is identical with determined value, just illustrate that blood gas analyzer is accurately, can continue to use, if the numerical value that detects is different with determined value, just illustrate that blood gas analyzer is inaccurate, need to adjust blood gas analyzer.In the described storer 205 that the data of first reagent, second reagent and sample detection are all preserved, the data that the user obtains according to test sample are judged and are analyzed, and carry out subsequent operation.In the technical program, only utilize liquid, without gas, therefore without gas cylinder, make things convenient for transportation and the movement of instrument; Only utilize liquid, use also very simply, the trouble of avoided reducing pressure because using gas to need, insulation, humidifying bringing; Avoid having reduced the probability that breaks down because liquid enters the fault that gas circuit produces, thus the reliability of raising instrument.
Embodiment 2, referring to Fig. 2, main channel 102 arranged in the needle-valve 101, and first thief hatch 105 and second thief hatch 106 are arranged on the main channel 102, and described first thief hatch 105 connects first passage 103, and described second thief hatch 106 connects second channel 104; First reagent, second reagent, protein liquid removal and cleaning fluid enter main channel 102 in the needle-valve 101 by first passage 103, and 102 first thief hatch 105 enters follow-up flow channel tube 3 in the main channel; When cleaning stream, the cleaning fluid that enters main channel 102 is divided into two parts, a part enters flow channel tube 3 from first thief hatch 105, clean in the sales kit (SK) 2 and follow-up stream, enter waste fluid bag 7 at last, another part enters second channel 104 from second thief hatch 106, extracted out by the 3rd pump housing 6, enter waste fluid bag 7 at last, the blood gas analyzer calibration has been satisfied in the setting of each passage in the needle-valve 101, deproteinized, sampling and the needs that clean stream, easy to use, avoid having reduced the probability that breaks down because liquid enters the fault that gas circuit produces, thus the reliability of raising instrument.
Embodiment 3, referring to Fig. 1 and Fig. 2, first passage 103 connects detector of liquid 18, be convenient to first reagent, second reagent, protein liquid removal and cleaning fluid and enter main channel 102 in the needle-valve 101 by flow channel tube 3, described second channel 104 connects the 3rd pump housing 6 by flow channel tube 3, be convenient to cleaning fluid smoothly by the 3rd pump housing 6, enter waste fluid bag 7, thus the convenient stream that cleans.
Embodiment 4, referring to Fig. 3, blood gas analyzer also comprises sample collector 109, this sample collector 109 inserts second thief hatch 106, and sampling needle 107 inserts in the sample collector 109 by main channel 102, the sample in the draw samples collector 109, after extraction finishes, sampling needle 107 is extracted, and sample collector 109 is also extracted from second thief hatch 106, and is easy to use.
Embodiment 5, referring to Fig. 1 and Fig. 3, one end of sampling needle 107 inserts in the sample collector by main channel 102, detecting device 201 before the other end connects, these sampling needle 107 front ends have pin hole 108, under the effect of first pump housing 4, examination sampling needle 107 is extracted the sample in the sample collector out by the pin hole 108 of sidewall, sample enters described test membrane pipe by preceding detecting device 201, is convenient to detect, and is easy to use.
Embodiment 6, and referring to Fig. 1 to Fig. 3, a kind of using method of blood gas analyzer comprises the steps:
S1, determine first standard value: open the 6th solenoid valve 16, pin hole 108 is aimed at first thief hatch, 105, the first pump housings 4 and is rotated counterclockwise, and extracts first reagent in the first reagent bag 17.When detector of liquid 18 detects first reagent, close the 6th solenoid valve 16, open the 3rd solenoid valve 11, gas enters in the flow channel tube 3 by the air intake opening on the 3rd solenoid valve 11, first pump housing 4 continues to rotate counterclockwise, when the back detecting device 203 in the sales kit (SK) 2 detected first reagent, first pump housing 4 stopped operating, and the 3rd solenoid valve 11 cuts out.At this moment, be full of first reagent in sales kit (SK) 2 overall flow paths, electrode 204 begins test, and the data of test are kept in the storer, as first standard value.The 3rd solenoid valve 11 is opened then, and first pump housing 4 rotates counterclockwise in the first reagent suction waste fluid bag 7 in the stream;
S2, determine second standard value: open the 5th solenoid valve 14, pin hole 108 is aimed at second thief hatch, 106, the first pump housings 41 and is rotated counterclockwise, and extracts second reagent in the second reagent bag 15.When detector of liquid 18 detects second reagent, the 5th solenoid valve 14 cuts out, the 3rd solenoid valve 11 is opened, gas enters in the flow channel tube 3 by the air intake opening on the 3rd solenoid valve 11, first pump housing 4 continues to rotate counterclockwise, when the back detecting device 203 in the sales kit (SK) 2 detected second reagent, first pump housing 4 stopped operating.At this moment, be full of second reagent in sales kit (SK) 2 overall flow paths, electrode 204 begins test, and the data of test are kept in the storer, as second standard value.The 3rd solenoid valve 11 is opened, and first pump housing 4 rotates counterclockwise, in the second reagent suction waste fluid bag 7 in the stream;
S3, deproteinized: open the 4th solenoid valve 12, pin hole 108 is aimed at first thief hatch, 105, the first pump housings 4 and is rotated counterclockwise, and extracts the protein liquid removal in the 3rd reagent bag 13.When detector of liquid 18 detects protein liquid removal, described first pump housing 4 continues to be rotated counterclockwise, close the 4th solenoid valve 12 then, open the 3rd solenoid valve 11, the air intake opening on air the 3rd solenoid valve 11 enters in the flow channel tube 3, and first pump housing 4 continues to rotate counterclockwise, when the back detecting device 203 in the sales kit (SK) 2 detects protein liquid removal, first pump housing 4 continues to rotate counterclockwise, and when having protein liquid removal to enter waste fluid bag 7, closes the 3rd solenoid valve 11.At this moment, all be full of protein liquid removal in the overall flow paths, protein liquid removal stopped in stream 3 minutes, and blood protein residual in protein liquid removal and the stream is fully reacted.At last, first pump housing 4 rotates counterclockwise, in the deproteinized waste liquid suction waste fluid bag 7 in the flow channel tube 3;
S4, sampling: sampling needle 107 inserts in the sample, first pump housing 4 rotates counterclockwise draw samples, this first pump housing 4 continues to rotate counterclockwise 4 circles, sampling needle 107 is extracted out from sample, pin hole 108 communicates with atmosphere, first pump housing 4 continues to rotate counterclockwise, and in the detecting device 201, first pump housing 4 continued to twitch sample and travels forward before the sample in the stream was extracted into, preceding detecting device 201 constantly detects, when detecting sample by behind the preceding detecting device 201, first pump housing 4 stops operating, and sample was full of and detected film pipe 202 this moment, 204 pairs of samples of electrode detect, and testing result is kept in the storer 205.After detect finishing, first pump housing 4 rotates counterclockwise, and the sample in the stream is arranged in the waste fluid bag 7; And
S5, clean stream: open second solenoid valve 9, sampling needle 107 moves on to first thief hatch 105 in the needle-valve 101.Second pump housing 5 rotates counterclockwise the cleaning fluid that extracts in the 4th reagent bag 10, first solenoid valve, 8 pause switches, in the liquid that second pump extracts, form the gas-liquid segmentation, second pump housing 5 rotates continuously, in stream, push the liquid of gas-liquid segmentation to needle-valve 101, when first solenoid valve 8 by open close the gas-liquid segmentation that produces 9 sections after, first solenoid valve 8 often changes into to be opened, close second solenoid valve 9, the gas-liquid mixed flow direction needle-valve 101 that second pump housing 5 promotes in the stream, when the detector of liquid 18 in the stream detected cleaning fluid, first pump housing 4 rotated counterclockwise second pump housing 5 is pushed the cleaning fluid of a part of gas-liquid segmentation of valve pocket successively through first thief hatch 105, sales kit (SK) 2 is evacuated to waste fluid bag 7 to clean first thief hatch 105 to sales kit (SK) 2 part streams; Simultaneously the 3rd pump housing 6 clockwise rotates, and second pump housing 5 is shifted onto in the main channel 102 of needle-valve 101 and the liquid that overflows to another part gas-liquid segmentation of second thief hatch 106 is evacuated to waste fluid bag 7, to clean the main channel 102 of needle-valve 101.Second pump housing 5 promotes gas-liquid segmentation liquid inserting needle valve 101 continuously, and when detector of liquid 18 detected less than cleaning fluid, second pump housing 5 stopped operating, and first pump housing 4 and the 3rd pump housing 6 stop operating after the cleaning fluid in the stream all is extracted into waste fluid bag 7.
Among the step S4, the bottleneck of sample collector 109 inserts in second thief hatch 106, and sampling needle 107 passes main channel 102 and inserts in the sample collector 109, by the sample in the pin hole 108 draw samples collectors 109, extracted sample after, extract sampling needle 107 out, carry out subsequent operation, easy to use.
In first reagent and second reagent, the numerical value of target to be measured was determined before detecting, be known, the numerical value of twice detection is contrasted with two described definite values respectively, if the numerical value that detects is identical with determined value, just illustrate that blood gas analyzer is accurately, can continue to use, if the numerical value that detects is different with determined value, just illustrate that blood gas analyzer is inaccurate, need to adjust blood gas analyzer.In the described storer 205 that the data of first reagent, second reagent and sample detection are all preserved, the data that the user obtains according to test sample are judged and are analyzed, and carry out subsequent operation.Above-described embodiment replaces the method for gas of the prior art and liquid hybrid scaling by liquid calibration, uses more conveniently, avoid having reduced the probability that breaks down because liquid enters the fault that gas circuit produces, thus the reliability of raising instrument.
[0026] above content be in conjunction with concrete preferred implementation to further describing that the present invention does, can not assert that concrete enforcement of the present invention is confined to these explanations.For the general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, can also make some simple deduction or replace, all should be considered as belonging to protection scope of the present invention.

Claims (9)

1. blood gas analyzer, it is characterized in that, comprising: the needle-valve that places sampling stand, the sales kit (SK) that connects described needle-valve, first pump housing that connects described sales kit (SK), the waste fluid bag that connects described first pump housing, the detector of liquid that connects described needle-valve and second pump housing, the 4th reagent bag that connects described second pump housing by second solenoid valve, the 3rd solenoid valve that connects described detector of liquid, first solenoid valve that connects this second pump housing, the first reagent bag that connects described detector of liquid by the 6th solenoid valve, the second reagent bag that connects described detector of liquid by the 5th solenoid valve, connect the 3rd reagent bag of described detector of liquid and the 3rd pump housing that connects needle-valve and waste fluid bag by the 4th solenoid valve; In the sales kit (SK), an end of preceding detecting device connects needle-valve, and the other end connects detection film pipe and back detecting device successively, and back detecting device connects first pump housing; All connect by flow channel tube between aforementioned each parts; Storer connects detection film pipe by electrode; On first solenoid valve and second solenoid valve air intake opening is arranged.
2. blood gas analyzer according to claim 1, it is characterized in that: main channel, first passage and second channel are arranged in the described needle-valve, first thief hatch and second thief hatch are arranged on the main channel, and described first thief hatch connects first passage, and described second thief hatch connects second channel.
3. blood gas analyzer according to claim 2 is characterized in that: described first passage connects detector of liquid, and described second channel connects the 3rd pump housing by flow channel tube.
4. blood gas analyzer according to claim 3, it is characterized in that: also comprise the sample collector, this sample collector inserts the second thief hatch inside.
5. blood gas analyzer according to claim 4 is characterized in that: in the described sample collector sample is housed.
6. blood gas analyzer according to claim 5 is characterized in that: sampling needle one end inserts in the sample collector by the main channel, and detecting device before the other end connects has pin hole on this sampling needle.
7. the using method of blood gas analyzer according to claim 6, its feature in, comprise the steps:
S1, determine first standard value: open the 6th solenoid valve, first pump housing extracts first reagent in the first reagent bag by flow channel tube; When detector of liquid detects first reagent, close the 6th solenoid valve, open the 3rd solenoid valve, first reagent enters and detects in the film pipe; When the back detecting device detected first reagent, first pump housing stopped operating, and closes the 3rd solenoid valve, and electrode begins test, and the data of test are kept in the storer, as first standard value; Open the 3rd solenoid valve then, first pump housing is with in the first reagent suction waste fluid bag in the stream;
S2, determine second standard value: open the 5th solenoid valve, first pump housing extracts second reagent in the second reagent bag by flow channel tube; When detector of liquid detects second reagent, close the 5th solenoid valve, open the 3rd solenoid valve, second reagent enters and detects in the film pipe; When the back detecting device detected second reagent, first pump housing stopped operating, and electrode begins test, and the data of test are kept in the storer, as second standard value; Open the 3rd solenoid valve then, first pump housing is with in the second reagent suction waste fluid bag in the stream;
S3, deproteinized: open the 4th solenoid valve, first pump housing extracts protein liquid removal in the 3rd reagent bag by flow channel tube; When detector of liquid detected protein liquid removal, described first pump housing continued to be rotated counterclockwise, and closes the 4th solenoid valve then, opens the 3rd solenoid valve, and protein liquid removal enters and detects in the film pipe; When the back detecting device detected protein liquid removal, first pump housing was rotated further, and when protein liquid removal begins to enter waste fluid bag, closes the 3rd solenoid valve, and blood protein residual in protein liquid removal and the stream is fully reacted; At last, first pump housing rotates, in the deproteinized waste liquid suction waste fluid bag in the flow channel tube;
S4, sampling: sampling needle inserts in the sample, and first pump housing rotates counterclockwise, draw samples; Sampling needle is extracted out from sample then, first pump housing is extracted into the sample in the stream and detects in the film pipe through preceding detecting device, sample detecting device before out-of-date constantly detects, after sample passes through preceding detecting device, first pump housing stops operating, and the electrode pair sample detects, and testing result is kept in the storer, first pump rotates, and the sample in the stream is arranged in the waste fluid bag; And
S5, clean stream: the first solenoid valve pause switch, open second solenoid valve, second pump housing is extracted into main channel in the needle-valve by flow channel tube with the cleaning fluid in the 4th reagent bag; First solenoid valve often changes into to be opened, and closes second solenoid valve, and first pump housing is evacuated to waste fluid bag through first thief hatch, sales kit (SK) successively with a part of cleaning fluid that second pump housing pushes the main channel; Simultaneously the 3rd pump housing is shifted second pump housing onto in the main channel of needle-valve and another part cleaning fluid of overflowing to second thief hatch is evacuated to waste fluid bag; Second pump housing rotates continuously, and till detector of liquid detected less than cleaning fluid, first pump housing and the 3rd pump housing stopped operating after the cleaning fluid in the stream all is extracted into waste fluid bag.
8. the using method of blood gas analyzer according to claim 7, it is characterized in that: among the described step S1, the pin hole of sampling needle is positioned at first thief hatch, and first reagent first passage of flowing through enters the sampling needle from pin hole; Among the described step S2, the pin hole of sampling needle is positioned at first thief hatch, and second reagent first passage of flowing through enters the sampling needle from pin hole.
9. the using method of blood gas analyzer according to claim 8, it is characterized in that: among the step S4, the bottleneck of sample collector inserts in second thief hatch, and sampling needle passes the main channel and inserts in the sample collector, by the sample in the pin hole draw samples collector.
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