CN102697438A - Capsule enteroscopy system with function of CCD (couple charged device) and function of optical coherence tomography - Google Patents
Capsule enteroscopy system with function of CCD (couple charged device) and function of optical coherence tomography Download PDFInfo
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- CN102697438A CN102697438A CN2012100169896A CN201210016989A CN102697438A CN 102697438 A CN102697438 A CN 102697438A CN 2012100169896 A CN2012100169896 A CN 2012100169896A CN 201210016989 A CN201210016989 A CN 201210016989A CN 102697438 A CN102697438 A CN 102697438A
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Abstract
The invention relates to a capsule enteroscopy system with a function of CCD (couple charged device) and a function of optical coherence tomography. The capsule enteroscopy system comprises a capsule enteroscope with the function of optical coherence tomography, an in-vitro receiving device and a computer system. The capsule enteroscope with the function of optical coherence tomography is provided with a casing. A power module, an electronic CCD photographic system, an optical coherence tomography module, a first image processing module, a second image processing module, a storage and communication module and an auxiliary structure are arranged in the casing. The capsule enteroscopy system combines electronic CCD technology, optical coherence tomography technology and capsule enteroscope technology. Normal surface images and tomographic images of intestinal walls can be acquired respectively by the electronic CCD photographic system and the optical tomography module. Conditions of human gastrointestinal tracts can be revealed more really and objectively. The gastrointestinal tracts can be diagnosed effectively and more accurately.
Description
Technical field
The invention belongs to medical instruments field, specifically, the present invention relates to a kind of capsule small intestinal mirror system.
Background technology
The capsule endoscope full name is " an intelligent capsule digestive tract endoscope system ", claims again " medical wireless scope ".Its principle is the intelligent capsule of built-in shooting of person under inspection's administered through oral and signal transmitting apparatus; Make it motion and photographic images in digestive tract by peristalsis of the digest tract; The doctor utilizes external image recorder and image workstation; Understand person under inspection's whole digestive tract situation, thereby its state of an illness is made diagnosis.Capsule endoscope has inspection convenience, no wound, no lead, no pain, no cross infection, does not influence patient's advantages such as operate as normal; Expanded the visual field of digestive tract examining; Overcome traditional toleration that the plug-in type scope had poor, be not suitable for old and defective such as the state of an illness is critical, be the especially prefered method of diagnosis of small bowel diseases of digestive tract disease.
Present traditional endoscopic system; The most of medium that adopts cold light source as endoscope illumination of its mode, through conventional prism optical system or electronic CCD (Charge-coupled Device, charge coupled cell) optical system to obtain the image of human organ cavity tissue; Be used as the diagnosis basis of disease with visual mode; Pathological changes in the general visible human organ can obtain through the observation of naked eyes, and some potential disease can not show character, and the image that feeds back according to endoscope is difficult to diagnosis; Must obtain through getting modes such as biopsy, this is one of them weakness of conventional endoscope.The history that the development history of endoscope moves towards the light from dark promptly supplies light to observe from the unglazed cold light source of observing, and is having under the condition of light, and the doctor can observe the looks in the gastrointestinal tract through the optical system of endoscope.
Optical coherent chromatographic imaging (Optical Coherence Tomography; OCT) techniques make use weak coherent light principle of interference; Detect the backscatter signals of tested tissue different depth; And obtain organizing two dimension or three dimensional depth structural images through scanning, have characteristics such as radiationless, non-intruding, high-resolution and high detection sensitivity.The OCT technology has obtained effective application in ophthalmologic examination, and gets involved in the human organ, the microminiaturization of OCT technology is applied to intraorganic disease detect, and is effectively carried out as yet at present.
Summary of the invention
To the above technical problem that will solve; The objective of the invention is to propose the capsule small intestinal mirror system of a kind of CCD of having function and optical coherent chromatographic imaging function; It utilizes optical correlation chromatography imaging technique and CCD technology as the core Observations Means; In conjunction with the advantage of capsule endoscope, utilize new method and visual angle that intestinal is observed.
In order to achieve the above object, the present invention realizes through following technical scheme:
A kind of capsule small intestinal mirror system with CCD function and optical coherent chromatographic imaging function; Comprise the capsule small intestinal mirror with CCD function and optical coherent chromatographic imaging function, external receiving system and computer system; The capsule small intestinal mirror of the said CCD of having function and optical coherent chromatographic imaging function has a shell; This shell is the semicircle capsule shape hermetically-sealed construction in two; Be provided with power module in the said shell; And the electronic CCD camera system that links to each other with this power module respectively, optical coherent chromatographic imaging module, first image processing module, second image processing module and storage and communication module; Near two nose circle settings of said shell, said electronic CCD camera system, said first image processing module link to each other with said storage and communication module successively respectively for said electronic CCD camera system and said optical coherent chromatographic imaging module, and said optical coherent chromatographic imaging module, said second image processing module link to each other with said storage and communication module successively; Also be provided with auxiliary structure in the said shell, it is used for fixing each module of said enclosure;
Said electronic CCD camera system is near a nose circle setting of said shell; Be used to obtain the normal picture of digestive tract wall; And be sent to said first image processing module; Then after first image processing module is handled, its further analyzing and processing is become can supply the form that shows or store, be resent to said storage and communication module;
Said optical coherent chromatographic imaging module is provided with near another nose circle of said shell; Be used to obtain the tomography structural images of digestive tract wall and be sent to said second image processing module; Said second image processing module is used to receive the image that said optical coherent chromatographic imaging module is obtained; And its further analyzing and processing become can supply the form that shows or store, and be sent to said storage and communication module;
The picture that said storage and communication module are used to store said first image processing module and said second image processing module after handling, and the picture that is obtained to external receiving system emission through wireless transmission method, and analyze by said computer system.
As a kind of preferred implementation of the present invention; Said electronic CCD camera system is provided with the CCD object lens near said housing one nose circle; These CCD object lens link to each other with CCD chip, ccd image treatment circuit and CCD transmission line successively, and around being provided with light source, this light source provides brightness and takes digestive tract wall image by said CCD object lens around the said CCD object lens; After CCD chip and ccd image processing circuit processes, be sent to said first image processing module via the CCD transmission circuit.
Further, 1/4 inch at the most of the size of said CCD chip, resolution at least 50 ten thousand pixels.
As a kind of preferred implementation of the present invention; Said optical coherent chromatographic imaging module comprises near the prism of said shell nose circle and the GRIN Lens that links to each other successively with this prism, optical fiber tissue and image information transmission structure; Said image information transmission structure links to each other with said second image processing module, and the transfer of data that optical correlation tomography module is collected to said second image processing module.
As a kind of preferred implementation of the present invention, 15 millimeters at the most of said housing diameters, 30 millimeters at the most of length.
As a kind of preferred implementation of the present invention, said power module is a recharge-able battery.
As a kind of preferred implementation of the present invention, said power module is a replaceable battery.
As a kind of preferred implementation of the present invention, said external receiving system is the Worn type receptor.
As a kind of preferred implementation of the present invention, said external receiving system is the hand-held receptor.
Capsule small intestinal mirror system with CCD function and optical coherent chromatographic imaging function of the present invention; Its method for using is following: after the inspection before patient's process art; Administered through oral has the capsule small intestinal mirror of optical coherent chromatographic imaging function; This capsule small intestinal mirror gets into gastral cavity and gets into through the intravital transportation naturally of people within a certain period of time through the human body esophagus and gets into duodenum road, little intestinal, big intestinal, colon and rectum successively; Finally the excretory function through human body excretes, and accomplishes the whole cycle of its work.After capsule small intestinal mirror gets into human body; The patient can wear external receiving system; And through should be external receiving system activation capsule small intestinal mirror, open the electronic CCD camera system and optical correlation tomography module is carried out the scanning between intestinal wall top layer and tomography, after treatment; Can store or through wireless transmit to external receiving equipment, and be presented at the monitor screen of computer system in real time.The doctor analyzes it through observing the top layer image and the intestinal wall faultage image of each digestive tract wall, obtains abundant more diagnosis basis.The doctor can detect the naked eyes about intestinal wall that capsule small intestinal mirror returns in real time can not observed image information.
Compared with prior art; The present invention adopts Optical Coherence Tomography Imaging Technology and electronic CCD technology as the core Observations Means; Optical Coherence Tomography Imaging Technology, electronic CCD technology are combined with capsule small intestinal mirror technology; Can obtain structure chart between top layer image and the tomography of gastrointestinal tract wall simultaneously, and respectively various images compared analysis, more comprehensively and objectively be familiar with gastrointestinal tract and related gastric enteropathy and become through system.
Capsule small intestinal mirror system with CCD function and optical coherent chromatographic imaging function of the present invention; Utilize the painless noinvasiveization of capsule endoscope microminiaturization and operation; In conjunction with the electronic CCD technology and in the few Optical Coherence Tomography Imaging Technology of using of medical domain, reach the purpose of diagnosis human gastrointestinal tract function and pathological changes.This capsule small intestinal mirror volume with CCD function and optical coherent chromatographic imaging function is little, in light weight; The patient takes the no fear in back; And simple to operate, there is not the complication that operation causes, structure chart between the tomography of top layer image that it obtains through the electronic CCD camera system and the intestinal wall that obtains through optical correlation tomography module; Can be more truly and disclose the situation of human gastrointestinal tract objectively, help more exactly gastrointestinal tract being carried out efficient diagnosis.
Description of drawings
Fig. 1 is the capsule small intestinal mirror system work sketch map of the CCD of having function provided by the invention and optical coherent chromatographic imaging function.
Fig. 2 is the structural representation of the capsule small intestinal mirror of the CCD of having function provided by the invention and optical coherent chromatographic imaging function.
The specific embodiment
Below in conjunction with the accompanying drawing and the specific embodiment the present invention is done further detailed explanation, but the present invention is not limited to following specific embodiment.
Fig. 1 is the work sketch map with capsule small intestinal mirror system of CCD function and optical coherent chromatographic imaging function of the present invention.As shown in Figure 1, the capsule small intestinal mirror system of the CCD of having function provided by the invention and optical coherent chromatographic imaging function is by the capsule small intestinal mirror 1 with CCD function and optical coherent chromatographic imaging function, and external receiving system and computer system 4 are formed.Said external receiving system is preferably Worn type receptor 2 or hand-held receptor 3.After before the patient is through strict in detail art, checking; The oral capsule small intestinal mirror 1 of swallowing the CCD of having function provided by the invention and optical coherent chromatographic imaging function; This capsule small intestinal mirror 1 trans-oral 5; Excrete successively through esophagus 51, stomach 52, duodenum 53, small intestinal 54, large intestine 55, and via anus 56, accomplish whole work period.After capsule small intestinal mirror 1 gets into human body; The patient can use external receiving system (for example Worn type receptor 2 or hand-held receptor 3); And activate said capsule small intestinal mirror 1 through this external receiving system; It is sent instruction, make capsule small intestinal mirror 1 in each organ of digestion, obtain the top layer image and the tomography structure chart of digestive tract wall simultaneously.The top layer image of these digestive tract walls and tomography structure chart can pass through wireless transmit to external receiving system, and be presented in real time on the display screen of computer system 4 after treatment.Computer system 4 can read the information that is obtained, and the doctor passes through the top layer image and the tomography structure chart of the digestive tract wall of each organ of observation, and it is analyzed, and can access abundant more diagnosis basis.
As shown in Figure 2, be the structural representation with capsule small intestinal mirror 1 of CCD function and optical coherent chromatographic imaging function provided by the invention.This capsule small intestinal mirror 1 with CCD function and optical coherent chromatographic imaging function has a shell 11; This shell 11 is the semicircle capsule shape hermetically-sealed construction in two; Its cross section is preferably circle, and it is preferably dimensioned to be 15 millimeters at the most of diameters, 30 millimeters at the most of length; So that the patient swallows, the material for preparing this shell 11 preferably can tolerate the strong acidic environment of gastral cavity.
Be provided with power module 15 in the said shell 11, and the electronic CCD camera system 12 that links to each other with this power module 15 respectively, optical coherent chromatographic imaging module 16, first image processing module 13, second image processing module 13 ' and storage and communication module 14.Said electronic CCD camera system 12 and said optical coherent chromatographic imaging module 16 are respectively near two nose circle settings of said shell 11; Said electronic CCD camera system 12, said first image processing module 13 link to each other with said storage and communication module 14 successively, and said optical coherent chromatographic imaging module 16, said second image processing module 13 ' link to each other with said storage and communication module 14 successively; Also be provided with auxiliary structure 17 in the said shell 11.
Said electronic CCD camera system 12 is used to obtain the normal top layer image of digestive tract wall near a nose circle setting of said shell 11, and is sent to said first image processing module 13.As shown in Figure 2, this electronic CCD camera system 12 is provided with CCD object lens 121 near the nose circle of said shell 11, and these CCD object lens 121 link to each other with transmission line with CCD chip, ccd image treatment circuit successively.Around being provided with light source 122, this light source 122 provides brightness and takes digestive tract wall image by CCD object lens 121, after CCD chip and ccd image processing circuit processes, is sent to first image processing module 13 via transmission circuit around the said CCD object lens 121.Preferably at the most 1/4 inch of said CCD chip size, resolution is at least 50 ten thousand pixels preferably.First image processing module 13 is used to receive the image that said electronic CCD camera system 12 is obtained, and its further analyzing and processing is become can supply the form that shows or store, is sent to said storage and communication module 14.
Said optical coherent chromatographic imaging module 16 is provided with near another nose circle of said shell 11, is used to obtain the tomography structural images of digestive tract wall, and is sent to said second image processing module 13 '.Said optical coherent chromatographic imaging module 16 comprises prism 161 and the GRIN Lens that links to each other successively with this prism 161, optical fiber tissue and the image information transmission structure that is provided with near said shell 11 nose circles; Said prism 161 is used to obtain the tomography structured data of digestive tract wall; Said image information transmission structure links to each other with said second image processing module 13 ', and the transfer of data that optical correlation tomography module 16 is collected to said image processing module 13 '.Said second image processing module 13 ' is used to receive the image that said optical coherent chromatographic imaging module 16 is obtained, and its further analyzing and processing is become can supply the form that shows or store, and be sent to said storage and communication module 14;
Said power module 15 is used to said shell 11 interior each module the operate as normal energy needed is provided, and it is preferably recharge-able battery or replaceable battery.
Said storage and communication module 14 are used for accepting and store the picture after said first image processing module 13 and the 13 ' processing of second image processing module; And the picture that is obtained to external receiving system (for example Worn type receptor 2 or hand-held receptor 3) emission through wireless transmission method, and analyze by said computer system 4;
Be provided with auxiliary structure 17 in the said shell 11, this auxiliary structure 17 is used for fixing said shell 11 inner each module, and it is preferably and comprises stationary frame structure.
The present invention obtains the top layer image of digestive tract wall through electronic CCD camera system 12; Obtain the tomography structural images of digestive tract wall simultaneously through optical coherent chromatographic imaging module 16; And respectively after first image processing module 13 and second image processing module 13 ' are handled; Outside human body, launch image in real time through storage and communication module 14; Perhaps with image storage in this storage and communication module 14, carry out reads image data by external computer system 4 again after waiting to discharge human body, so as for the doctor provide when using traditional gastrointestinal mirror status information that can't obtain, true and reliable; Enrich the means that intestinal is observed and diagnosed, also further guaranteed the accuracy of diagnosis.
Claims (9)
1. capsule small intestinal mirror system with CCD function and optical coherent chromatographic imaging function; Comprise the capsule small intestinal mirror with CCD function and optical coherent chromatographic imaging function, external receiving system and computer system; It is characterized in that: the capsule small intestinal mirror of the said CCD of having function and optical coherent chromatographic imaging function has a shell; This shell is the semicircle capsule shape hermetically-sealed construction in two; Be provided with power module in the said shell; And the electronic CCD camera system that links to each other with this power module respectively, optical coherent chromatographic imaging module, first image processing module, second image processing module and storage and communication module; Near two nose circle settings of said shell, said electronic CCD camera system, said first image processing module link to each other with said storage and communication module successively respectively for said electronic CCD camera system and said optical coherent chromatographic imaging module, and said optical coherent chromatographic imaging module, said second image processing module link to each other with said storage and communication module successively; Also be provided with auxiliary structure in the said shell, it is used for fixing each module of said enclosure;
Said electronic CCD camera system is near a nose circle setting of said shell; Be used to obtain the normal picture of digestive tract wall; And be sent to said first image processing module; Then after first image processing module is handled, its further analyzing and processing is become can supply the form that shows or store, be resent to said storage and communication module;
Said optical coherent chromatographic imaging module is provided with near another nose circle of said shell; Be used to obtain the tomography structural images of digestive tract wall and be sent to said second image processing module; Said second image processing module is used to receive the image that said optical coherent chromatographic imaging module is obtained; And its further analyzing and processing become can supply the form that shows or store, and be sent to said storage and communication module;
The picture that said storage and communication module are used to store said first image processing module and said second image processing module after handling, and the picture that is obtained to external receiving system emission through wireless transmission method, and analyze by said computer system.
2. capsule small intestinal mirror system according to claim 1; It is characterized in that: said electronic CCD camera system is provided with the CCD object lens near said housing one nose circle; These CCD object lens link to each other with CCD chip, ccd image treatment circuit and CCD transmission line successively; Said CCD object lens are on every side around being provided with light source; This light source provides brightness and takes digestive tract wall image by said CCD object lens, after CCD chip and ccd image processing circuit processes, is sent to said first image processing module via the CCD transmission circuit.
3. capsule small intestinal mirror system according to claim 2 is characterized in that: 1/4 inch at the most of the size of said CCD chip, resolution at least 50 ten thousand pixels.
4. capsule small intestinal mirror system according to claim 1; It is characterized in that: said optical coherent chromatographic imaging module comprises near the prism of said shell nose circle and the GRIN Lens that links to each other successively with this prism, optical fiber tissue and image information transmission structure; Said image information transmission structure links to each other with said second image processing module, and the transfer of data that optical correlation tomography module is collected to said second image processing module.
5. according to each described capsule small intestinal mirror system of claim 1 to 4, it is characterized in that: 15 millimeters at the most of said housing diameters, 30 millimeters at the most of length.
6. according to each described capsule small intestinal mirror system of claim 1 to 4, it is characterized in that: said power module is a recharge-able battery.
7. according to each described capsule small intestinal mirror system of claim 1 to 4, it is characterized in that: said power module is a replaceable battery.
8. according to each described capsule small intestinal mirror system of claim 1 to 4, it is characterized in that: said external receiving system is the Worn type receptor.
9. according to each described capsule small intestinal mirror system of claim 1 to 4, it is characterized in that: said external receiving system is the hand-held receptor.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012100169896A CN102697438A (en) | 2012-01-18 | 2012-01-18 | Capsule enteroscopy system with function of CCD (couple charged device) and function of optical coherence tomography |
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| CN2012100169896A CN102697438A (en) | 2012-01-18 | 2012-01-18 | Capsule enteroscopy system with function of CCD (couple charged device) and function of optical coherence tomography |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105361843A (en) * | 2015-11-30 | 2016-03-02 | 青岛大学附属医院 | Wireless capsule OCT (optical coherence tomography) endoscope system for gastrointestinal tract diagnosis and treatment |
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| CN202426489U (en) * | 2012-01-18 | 2012-09-12 | 广州宝胆医疗器械科技有限公司 | Capsule enteroscope system with CCD (Charge Coupled Device) function and optical coherence tomography function |
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Patent Citations (4)
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| US20080119740A1 (en) * | 2004-12-30 | 2008-05-22 | Iddan Gavriel J | Device, System, and Method for Optical In-Vivo Analysis |
| CN101495022A (en) * | 2006-07-24 | 2009-07-29 | 皇家飞利浦电子股份有限公司 | Capsule camera with variable illumination of the surrounding tissue |
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| CN105361843A (en) * | 2015-11-30 | 2016-03-02 | 青岛大学附属医院 | Wireless capsule OCT (optical coherence tomography) endoscope system for gastrointestinal tract diagnosis and treatment |
| CN105361843B (en) * | 2015-11-30 | 2019-03-19 | 青岛大学附属医院 | Wireless capsule OCT endoscopic system for gastrointestinal tract diagnosis and treatment |
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Application publication date: 20121003 |