CN102335465A - Blood perfusion device for treating uremia - Google Patents
Blood perfusion device for treating uremia Download PDFInfo
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- CN102335465A CN102335465A CN2010102374716A CN201010237471A CN102335465A CN 102335465 A CN102335465 A CN 102335465A CN 2010102374716 A CN2010102374716 A CN 2010102374716A CN 201010237471 A CN201010237471 A CN 201010237471A CN 102335465 A CN102335465 A CN 102335465A
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- perfusion device
- blood perfusion
- adsorbent resin
- average pore
- treatment
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Abstract
The invention discloses a blood perfusion device for treating uremia. The technical scheme of the blood perfusion device is as follows: the blood perfusion device is composed of a tank body and adsorbent resin sealed and filled in the tank body, wherein the adsorbent resin is styrene-divinylbenzene polymer microspheres with the specific physical parameters as follows: specific surface area of 2732 m<2>/g weight +/- 10%, average pore diameter of 3.696 nm +/- 10% and average pore volume of 1.279 mL/ g weight +/- 10%.
Description
Technical field under the invention:
The invention belongs to medical apparatus and instruments, especially for the medical apparatus and instruments of blood purification treatment.
The background of invention technology:
Adopting blood perfusion device to purify the blood is the medical new technique that developed recently gets up.The blood perfusion device of using clinically at present that has salvage drug to poison.The blood perfusion device of opiates poisonous substance excessive in the quick removing human body was once invented by applicant unit before the several years.Aspect the treatment uremia launch is being arranged successively in recent years; But up to the present; The existing uremia's blood perfusion device of treating does not still have clear and definite physical index at the adsorbent resin technical elements that uses, thereby has blindness, in clinical, can cure the situation of not suiting the medicine to the illness inevitably.Establishing clear and definite physical index to adsorbent resin is to produce the blood perfusion device product research problem that is suitable for.
The content of invention:
The objective of the invention is to propose the uremic blood perfusion device product technology of a kind of treatment scheme, adopt the resin of targeted characterization of adsorption, with developing treatment uremia new way.
The technical scheme of blood perfusion device of the present invention comprises that tank body and sealing are filled in a jar intravital adsorbent resin and constitute, and employed adsorbent resin is the SDEB styrene diethylenebenzene polymer microballoon, its
Concrete physical parameter is:
Specific surface area: 2732 meters squared per gram are heavy, and ± 10%;
Average pore size: 3.696 nanometers, ± 10%;
Average pore volume: 1.279 milliliters/grammes per square metre, ± 10%.
Difference with the prior art of the present invention:
Substantive distinguishing features of the present invention is that the adsorbent resin of employing has clear and definite physical index, the blindness of having avoided prior art to exist.
Marked improvement of the present invention is, in clinical, to but being difficult to the middle macromole poisonous substance that excretes through hemodialysis in the uremic patient blood, has obvious separation adsorption.
Embodiments of the invention are following:
Embodiment 1: patient's hole, uremic patient has been done and has been done dialysis treatment for a long time.
Adopt blood perfusion device treatment of the present invention 120 minutes, the patient has sensation easily.To 430 units before the molecule total amount art in the industry postoperative blood constituent assay before patient's art, postoperative 266 units.Clearance rate is 38.1%.
Embodiment 2: patient Chen, uremic patient has been done and has been done dialysis treatment for a long time.
Adopt blood perfusion device treatment of the present invention 120 minutes, the patient has sensation easily, has particularly obviously alleviated skin pruritus.To 410 units before the molecule total amount art in the industry postoperative blood constituent assay before patient's art, postoperative 272 units.Clearance rate is 33.6%.
Embodiment 3: the patient ends certain, and uremic patient has been done and done dialysis treatment for a long time.
Adopt blood perfusion device treatment of the present invention 120 minutes, the patient has sensation easily.To 394 units before the molecule total amount art in the industry postoperative blood constituent assay before patient's art, postoperative 266 units.Clearance rate is 32.3%.
Claims (1)
1. the uremic blood perfusion device of treatment is filled in a jar intravital adsorbent resin by tank body and sealing and constitutes, and it is characterized in that:
Employed adsorbent resin is the SDEB styrene diethylenebenzene polymer microballoon, and its concrete physical parameter is:
Specific surface area: 2732 meters squared per gram are heavy, and ± 10%;
Average pore size: 3.696 nanometers, ± 10%;
Average pore volume: 1.279 milliliters/grammes per square metre, ± 10%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102374716A CN102335465A (en) | 2010-07-27 | 2010-07-27 | Blood perfusion device for treating uremia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102374716A CN102335465A (en) | 2010-07-27 | 2010-07-27 | Blood perfusion device for treating uremia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102335465A true CN102335465A (en) | 2012-02-01 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010102374716A Pending CN102335465A (en) | 2010-07-27 | 2010-07-27 | Blood perfusion device for treating uremia |
Country Status (1)
| Country | Link |
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| CN (1) | CN102335465A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103223197A (en) * | 2013-04-23 | 2013-07-31 | 天津市阳权医疗器械有限公司 | Combined medical apparatus device for toxemia blood purifying |
| CN103536977A (en) * | 2013-11-04 | 2014-01-29 | 于杰 | Hemoperfusion apparatus |
| CN104434954A (en) * | 2014-11-10 | 2015-03-25 | 苏州维泰生物技术有限公司 | Middle molecular adsorbent for uremia and preparation method of middle molecular adsorbent |
| CN104857015A (en) * | 2013-08-12 | 2015-08-26 | 天津市阳权医疗器械有限公司 | Styrene type novel-structure adsorption resin for de-addiction and detoxification |
| CN109689124A (en) * | 2016-09-06 | 2019-04-26 | 甘布罗伦迪亚股份公司 | Liver system |
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| US5839258A (en) * | 1995-11-28 | 1998-11-24 | Mitsubishi Chemical Corporation | Storing method for adsorbent particles |
| US6527735B1 (en) * | 2000-04-27 | 2003-03-04 | Renaltech International Llc | Method of peritoneal dialysis |
| CN101088600A (en) * | 2006-06-12 | 2007-12-19 | 天津协成昌国际贸易有限公司 | Prepn and product of adsorbing material |
| CN101357963A (en) * | 2007-08-01 | 2009-02-04 | 中国科学院大连化学物理研究所 | Preparation method of polystyrene-divinylbenzene microspheres for bilirubin adsorption |
| CN101657224A (en) * | 2007-01-12 | 2010-02-24 | 贝尔科股份责任有限公司 | Polymer resin is used for the purposes of the external removal inflammatory mediator of adsorptivity in the treatment of whole body inflammatory relevant disease |
| CN101693750A (en) * | 2009-10-16 | 2010-04-14 | 崔建 | Preparation method of macroporous absorption resin |
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2010
- 2010-07-27 CN CN2010102374716A patent/CN102335465A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5839258A (en) * | 1995-11-28 | 1998-11-24 | Mitsubishi Chemical Corporation | Storing method for adsorbent particles |
| US6527735B1 (en) * | 2000-04-27 | 2003-03-04 | Renaltech International Llc | Method of peritoneal dialysis |
| CN101088600A (en) * | 2006-06-12 | 2007-12-19 | 天津协成昌国际贸易有限公司 | Prepn and product of adsorbing material |
| CN101657224A (en) * | 2007-01-12 | 2010-02-24 | 贝尔科股份责任有限公司 | Polymer resin is used for the purposes of the external removal inflammatory mediator of adsorptivity in the treatment of whole body inflammatory relevant disease |
| CN101357963A (en) * | 2007-08-01 | 2009-02-04 | 中国科学院大连化学物理研究所 | Preparation method of polystyrene-divinylbenzene microspheres for bilirubin adsorption |
| CN101693750A (en) * | 2009-10-16 | 2010-04-14 | 崔建 | Preparation method of macroporous absorption resin |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103223197A (en) * | 2013-04-23 | 2013-07-31 | 天津市阳权医疗器械有限公司 | Combined medical apparatus device for toxemia blood purifying |
| CN104857015A (en) * | 2013-08-12 | 2015-08-26 | 天津市阳权医疗器械有限公司 | Styrene type novel-structure adsorption resin for de-addiction and detoxification |
| CN104923185A (en) * | 2013-08-12 | 2015-09-23 | 天津市阳权医疗器械有限公司 | Medical adsorption resin for eliminating H-N- macromolecular virus |
| CN104923185B (en) * | 2013-08-12 | 2017-10-24 | 天津市阳权医疗器械有限公司 | Medical polymeric adsorbent for removing H N macromoleculars virus |
| CN103536977A (en) * | 2013-11-04 | 2014-01-29 | 于杰 | Hemoperfusion apparatus |
| CN104434954A (en) * | 2014-11-10 | 2015-03-25 | 苏州维泰生物技术有限公司 | Middle molecular adsorbent for uremia and preparation method of middle molecular adsorbent |
| CN109689124A (en) * | 2016-09-06 | 2019-04-26 | 甘布罗伦迪亚股份公司 | Liver system |
| CN109689124B (en) * | 2016-09-06 | 2021-12-03 | 甘布罗伦迪亚股份公司 | Liver support system |
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Application publication date: 20120201 |