CN102253195B - Full-automatic immunochromatographic analyzer - Google Patents

Full-automatic immunochromatographic analyzer Download PDF

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Publication number
CN102253195B
CN102253195B CN 201110176382 CN201110176382A CN102253195B CN 102253195 B CN102253195 B CN 102253195B CN 201110176382 CN201110176382 CN 201110176382 CN 201110176382 A CN201110176382 A CN 201110176382A CN 102253195 B CN102253195 B CN 102253195B
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pusher arm
reagent
automatic
full
incubation
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CN102253195A (en
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黄桂民
黄波
于方治
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SHANGHAI BEIXI BIOLOGICAL TECHNOLOGY Co Ltd
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SHANGHAI BEIXI BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

The invention discloses a full-automatic immunochromatographic analyzer comprising a control unit, a sampling unit, a reagent providing unit and an incubation transmission detection unit, wherein, the control unit is respectively connected with the sampling unit, the reagent providing unit and the incubation transmission detection unit; the input ends of the reagent providing unit and the incubation transmission detection unit are horizontally connected; the reagent providing unit is used for receiving reagent sending signals of the control unit, and arranging a corresponding test bar box in the reagent providing unit at the input end of the incubation transmission detection unit; and the sampling unit is used for receiving sampling signals of the control unit, and adding the sample to bedetected into the test bar box positioned at the input end of the incubation transmission detection unit. By utilizing the full-automatic immunochromatographic analyzer provided by the invention, theimmunity analyzing operation technology is improved, the error of manual operation is avoided, and the powerful guarantee is provided for the homogeneity of the reaction conditions, such as temperature and time and the like, thus the accuracy of the immunity analysis can be effectively improved.

Description

A kind of full-automatic immunochromatographiassays assays instrument
Technical field
The present invention relates to a kind of full-automatic immunochromatographiassays assays instrument, belongs to the biochemical analyzer technical field.
Background technology
Immunochromatography is the immunoassay mode that comes across a kind of uniqueness at the initial stage eighties, it is solid phase with the fibre strip chromatographic material often, make sample solution swimming on chromatography strip by capillary action, and make the immune response that high special high-affinity takes place at the acceptor (as antibody or antigen) of determinand on determinand in the sample and the chromatographic material simultaneously, immune complex is by enrichment or be trapped in certain zone (detect band) of chromatographic material in the chromatography process, the label (as collaurum) that can estimate by enzyme reaction or direct utilization obtains experimental phenomena (as colour developing) intuitively, free label is then crossed and is detected band, reaches the purpose of separating automatically with binding label.This analytical technology is simple to operate, and analysis result is clear fast, is easy to judge, therefore, is highly suitable for hospitals at different levels, family or individual in the utilization of aspects such as diagnosis, health care, health check-up.
Immunochromatographiassays assays is divided into qualitative and quantitative, and wherein qualitative analysis mainly is that the operator is added to sample to be checked in the sample well of strip, reads the result by naked eyes, the qualitative interpretation of making or not having after the wait regular hour; After quantitative test mainly is the manual application of sample of operator, or behind the certain hour strip is put into analytical instrument at interval, read many or few quantitative result by instrument.Therefore, no matter qualitative analysis or quantitative test, their common feature is that the application of sample process all is manual operations, and only is suitable for a spot of sample, and the overall process of sample analysis all must have operating personnel on duty simultaneously, can not realize full-automatic the analysis.
Summary of the invention
Rely on manually-operated defective at the immunochromatographiassays assays that exists in the prior art, the purpose of this invention is to provide a kind of full-automatic immunochromatographiassays assays instrument, can when increasing work efficiency, reduce the error that manual operations produces, thereby improve the precision that detects.
For achieving the above object, the technical solution used in the present invention is as follows:
A kind of full-automatic immunochromatographiassays assays instrument comprises that control module, sampling unit, reagent provide unit and incubation transmission detecting unit, and described control module provides unit and incubation transmission detecting unit to be connected with sampling unit, reagent respectively; Described reagent provides the unit to be connected mutually with the input end level of incubation transmission detecting unit.
Described reagent provides the unit to comprise strip box, rotating disc, reagent storehouse and push mechanism, and described rotating disc, reagent storehouse and push mechanism all are connected with control module; Described reagent storehouse is provided with the strip box of single kind from top to bottom along circumferentially evenly being located on the rotating disc at interval in the single reagent storehouse; The horizontal level of described reagent storehouse base plate is consistent with the horizontal level of described incubation transmission detecting unit input end, the base plate upper edge axis in reagent storehouse is provided with gathering sill, the front shroud lower end in reagent storehouse is provided with opening, the shape of opening is corresponding with the shape of strip box xsect, the back shroud lower end in reagent storehouse is provided with pilot hole, and described pilot hole and opening are connected with gathering sill respectively; Described push mechanism is located at the rear in the reagent storehouse that is connected mutually with incubation transmission detecting unit input end and gathering sill and pilot hole by this reagent storehouse are connected mutually with the strip box.
Described push mechanism can adopt the promotion structure, also can adopt hooking structure.
When push mechanism adopt to promote structure, can take in following four kinds of concrete structures any one:
Described push mechanism comprises pusher arm, driving-belt and motor, and described driving-belt is connected with motor and pusher arm respectively, and the xsect of described pusher arm can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises pusher arm, screw rod and motor, and described motor links to each other with an end of screw rod, and screw rod also is connected with pusher arm; The xsect of described pusher arm can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises electromagnet, permanent magnet, slide rail and pusher arm, described electromagnet is located at the two ends of slide rail respectively, the lower end of described pusher arm is sheathed on the outside of slide rail, and the both sides, lower end of described pusher arm are provided with permanent magnet, and described permanent magnet is relative with electromagnet; The xsect of described pusher arm can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises pusher arm, gear bar and the motor that has gear, and described pusher arm is located at the top of gear bar and is fixedlyed connected with the gear bar, and described gear bar also meshes with gear; The xsect of described pusher arm can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box.
Above-mentioned pilot hole preferably is strip structure, and pilot hole and gathering sill are perpendicular
When push mechanism adopts hooking structure, can take in following four kinds of concrete structures any one:
Described push mechanism comprises pusher arm, driving-belt and motor, described driving-belt is connected with motor and pusher arm respectively, the outer end of described pusher arm is hook-shape structure, and the inboard of described hook-shape structure can be stretched into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises pusher arm, screw rod and motor, and described motor links to each other with an end of screw rod, and screw rod also is connected with pusher arm; The outer end of described pusher arm is hook-shape structure, and the inboard of described hook-shape structure can be stretched into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises electromagnet, permanent magnet, slide rail and pusher arm, described electromagnet is located at the two ends of slide rail respectively, the lower end of described pusher arm is sheathed on the outside of slide rail, and the both sides, lower end of described pusher arm are provided with permanent magnet, and described permanent magnet is relative with electromagnet; The outer end of described pusher arm is hook-shape structure, and the inboard of described hook-shape structure can be stretched into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises pusher arm, gear bar and the motor that has gear, and described pusher arm is located at the top of gear bar and is fixedlyed connected with the gear bar, and described gear bar also meshes with gear; The outer end of described pusher arm is hook-shape structure, and the inboard of described hook-shape structure can be stretched into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Wherein said pilot hole is strip structure, and pilot hole and gathering sill are perpendicular.
The kind of described strip box is one or more.
Described incubation transmission detecting unit comprises lucifuge constant temperature cover, travelling belt and detection part, and the output terminal of described travelling belt is connected with the input end of detection part; Described lucifuge constant temperature covers at the periphery, input end rear of travelling belt and the periphery of detection part.
Described detection part comprises one or more in excitation light source/emission light-receiving, visible light source/visible light reception and the visible light source/CCD photographed images analysis.
Described incubation transmission detecting unit adopts chain delivery structure or circumference formula transfer structure.
Described sampling unit comprises sample needle and clean-out opening, and the sampled signal that described sample needle receives control module is added to sample to be checked in the strip box that is positioned at incubation transmission detecting unit input end; Described sample needle also receives the purge signal of described control module and sample needle is stretched into clean-out opening.
Described full-automatic immunochromatographiassays assays instrument also comprises quantitative charger, and described quantitative charger is connected with control module, and quantitative charger is located in the incubation transmission detecting unit, and is connected with the medium position of incubation transmission detecting unit.
Described full-automatic immunochromatographiassays assays instrument also comprises alarm unit, and described alarm unit is connected with control module.
Adopt a kind of full-automatic immunochromatographiassays assays instrument of the present invention, can provide the unit that the strip box is provided by reagent, according to the control module instruction corresponding strip box is sent for test and used; Sampling unit makes circumference according to the instruction of control module or sampling and application of sample are carried out in three-dimensional motion, and cleans automatically after portion sample pipetting volume to be checked is finished, to prevent the cross pollution of sample room; After incubation transmission detecting unit receives and adds the strip box of sample, enter the lucifuge flat-temperature zone and be incubated to and react completely, it is consistent that wherein required fully time of application of sample sample incubation reaction to be checked to the strip box and the incubation input end that transmits detecting unit moves to time of input end; At last, the strip box that is loaded with sample to be checked is tested, detection mode can be to read fluorometry or the chemiluminometry of photosignal, calculates measured value according to the signal power; Also can adopt the CCD pickup image, calculate measured value according to the gray-scale value of band.
Compared with prior art, the present invention has following beneficial effect:
One. the operative technique of perfect immunochromatography or immunity percolation, avoided manual error, assurance can be provided to the homogeneity of reaction conditionss such as temperature and time simultaneously, thereby the precision of test can be effectively improved.
Two. both be applicable to the test of multinomial order short run sample, also can have satisfied the automatic test of sample in enormous quantities, greatly improved work efficiency.
Three. realize high flux, automatic immunity, had bright development prospect.
Description of drawings
Fig. 1 is a kind of structural representation of full-automatic immunochromatographiassays assays instrument provided by the invention;
Fig. 2 is the structural representation that reagent of the present invention provides the unit;
Fig. 3 is a kind of structural representation of push mechanism of the present invention;
Fig. 4 is the another kind of structural representation of push mechanism of the present invention;
Fig. 5 is another structural representation of push mechanism of the present invention;
Fig. 6 is a kind of structural representation of pusher arm of the present invention;
Fig. 7 is the another kind of structural representation of full-automatic immunochromatographiassays assays instrument provided by the invention.
Embodiment
Further specify technical scheme of the present invention below in conjunction with drawings and Examples.
See also shown in Figure 1: a kind of full-automatic immunochromatographiassays assays instrument provided by the invention, comprise that control module (not shown), sampling unit 11, reagent provide unit 12 and incubation transmission detecting unit 13, control module provides unit 12 and incubation transmission detecting unit 13 to be connected with sampling unit 11, reagent respectively; Reagent provides unit 12 to be connected mutually with the input end level of incubation transmission detecting unit 13.Wherein, the reagent reagent that provides unit 12 to receive control modules sends behind the signal input end that reagent is provided corresponding strip box 121 in the unit 12 be arranged on incubation transmission detecting unit 13; Sampling unit 11 receives the sampled signal of control module and sample 20 addings to be checked is positioned at the strip box 121 of incubation transmission detecting unit 13 input ends.Can be suitable for the fluorescence labeling technology in the strip box 121, also can be suitable for other technology.
Incubation transmission detecting unit 13 comprises lucifuge constant temperature cover 131, travelling belt 132 and detection part 133, and the output terminal of travelling belt 132 is connected with the input end of detection part 133.Lucifuge constant temperature cover 131 is located at the periphery, input end rear of travelling belt 132 and the periphery of detection part 133.Detection part 133 comprises one or more in excitation light source/emission light-receiving, visible light source/visible light reception and the visible light source/CCD photographed images analysis.F is the moving direction of travelling belt 132 among the figure.
Sampling unit 11 comprises sample needle 111 and clean-out opening 112, and sample needle 111 is added to the strip box 121 that is positioned at incubation transmission detecting unit 13 input ends with sample 20 to be checked after receiving the sampled signal of control modules.Application of sample 111 pins also receive the purge signal of control module and sample needle 11 are stretched into clean-out opening 112.
See also shown in Figure 2 again: described reagent provides unit 12 to comprise strip box 121, rotating disc 122, reagent storehouse 123 and push mechanism 124, rotating disc 122, reagent storehouse 123 and push mechanism 124 all are connected with control module, several reagent storehouses 123 are along circumferentially evenly being located on the rotating disc 122 at interval, be provided with the strip box 121 of single kind in the single reagent storehouse 123 from top to bottom, the kind of strip box 121 is one or more, the strip box 121 of single kind also can be arranged in a plurality of reagent storehouse 123, but different types of strip box 121 must be arranged in the corresponding reagent storehouse 123, need to prove that at this different types of strip box 121 can not be arranged in the same reagent storehouse 123.The horizontal level of the base plate 125 in reagent storehouse 123 is consistent with the horizontal level of incubation transmission detecting unit 13 input ends, the base plate 125 upper edge axis in reagent storehouse 123 are provided with gathering sill, front shroud 126 lower ends in reagent storehouse 123 are provided with opening 127, the shape of opening 127 is corresponding with the shape of strip box 121 xsects, back shroud 128 lower ends in reagent storehouse 123 are provided with pilot hole 129, pilot hole 129 is strip structure, and pilot hole 129 is vertical with gathering sill.Pilot hole 129 and opening 127 also are connected with gathering sill respectively.Push mechanism 124 is located at the rear in the reagent storehouse that is connected mutually with travelling belt 132 input ends and gathering sill and pilot hole by this reagent storehouse are connected mutually with the strip box.Push mechanism 124 comprises pusher arm 1241, driving-belt 1242 and motor 1243 that can rotating, driving-belt 1242 is connected with motor 1243 and pusher arm 1241 respectively, and the xsect of pusher arm 1241 can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box.
Push mechanism 124 also can adopt screw drive structure as shown in Figure 3, wherein push mechanism 124 comprises pusher arm 1244, screw rod 1245 and motor 1246 that can rotating, motor 1246 is connected with an end of screw rod 1245, screw rod 1245 also is connected with pusher arm 1244, and the xsect of pusher arm 1244 can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box.
Push mechanism 124 can also adopt electromagnetism push-pull configuration as shown in Figure 4, wherein push mechanism 124 comprises electromagnet 1247, permanent magnet 1248, slide rail 1249 and pusher arm 1250, electromagnet 1247 is located at the two ends of slide rail 1249 respectively, the lower end of pusher arm 1250 is sheathed on the outside of slide rail 1249, the both sides, lower end of pusher arm 1250 are fixed with permanent magnet 1248, and permanent magnet 1248 is relative with electromagnet 1247.The xsect of pusher arm 1250 can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box.During use, make it produce magnetic field by the corresponding electromagnet 1247 of power connection, so just can attract the permanent magnet corresponding with it 1248, move thereby drive pusher arm 1250.
Push mechanism 124 can also adopt structure as shown in Figure 5, push mechanism 124 comprises pusher arm 1251, gear bar 1252 and the motor 1253 that has gear, pusher arm 1251 is located at the top of gear bar 1252 and is fixedlyed connected with gear bar 1252, and gear bar 1252 also meshes with gear.The xsect of pusher arm 1251 can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box.
See also pusher arm shown in Figure 6 again, by the pusher arm among Fig. 2, Fig. 3, Fig. 4 and Fig. 5 being changed into the hook-shape structure of Fig. 6, so just push mechanism can be changed into the delivery formula of colluding by the promotion pattern, the main body of push mechanism namely can place the below of travelling belt 132, like this can be so that strip pick-up unit of the present invention integrated level spatially increases.
Full-automatic immunochromatographiassays assays instrument of the present invention also comprises quantitative charger 14, and described quantitative charger 1 is located in the incubation transmission detecting unit 13, and is connected with the medium position of incubation transmission detecting unit 13.The substrate sample adding device that adds the sample to be checked of substrate after quantitative charger 14 can be used as and needs.
Full-automatic immunochromatographiassays assays instrument of the present invention also comprises the alarm unit (not shown), and alarm unit is connected with control module.
Incubation transmission detecting unit 13 not only can adopt circumference formula transfer structure as shown in Figure 1, can also adopt chain delivery structure as shown in Figure 7.
Control module adopts computer or single card microcomputer programming Control, is equipped with built-in miniprinter and LIS interface.And carry internal memory and can roll and store a certain amount of testing result and data such as calibration, Quality Control.Control module comprises setting, inquires about and safeguards three partial functions.
Part wherein is set comprises setting commonly used, project setting and task setting at least.The commonly used setting mainly is to date, time and the setting of printing ON/OFF etc.The project setting comprises title setting, the setting of strip box, unit setting and term of reference etc., in setting, the strip box only allows to establish a kind of strip box in a reagent storehouse, also can take a plurality of reagent storehouse by a kind of strip box, after the strip box in the reagent storehouse uses up, can be according to setting the next reagent storehouse of placing identical strip box of migrating automatically, unit sets and comprises ng/ml, pg/ml or ug/ml etc.The task setting comprises operator and sample ID to be checked number setting, the setting of sample position and the setting of test item, and wherein being set in of sample position can be selected to continue or from initial 1 the same day.Also allow a sample to be checked to do Multitest, namely a sample to be checked can adopt 121 pairs of corresponding test items of different types of strip box to test simultaneously.
Query portion comprises result queries at least, by date, option such as ID number or project query.
Service portion comprises that at least light signal strength is proofreaied and correct, project calibration curve correction (can import operation during the change of reagent lot number by magnetic card), and wherein the light signal strength calibration function need be encrypted, and the user must not be from line operate.
During use, at first carry out the self check step, the self check step comprises that travelling belt 132 fortune circle no abnormal, light path detection signal in the detection part 133 is no abnormal, sample needle 111 cleans, and suction sample, application of sample move no abnormal, and be no abnormal for cleansing solution, cleaning solution and discharge of wastewater in the clean-out opening 112.After above-mentioned self check step is finished, send the self check step and finish signal, wait for operating personnel's input test instruction.Operating personnel set test instruction then, press beginning key test beginning, the setting in advance of control module basis is with the strip box the implementation of supply measurement in the corresponding reagent storehouse, and sample disc to be checked moves into place simultaneously, treats the sample product by sample needle 111 and carries out actions such as inhaling sample and application of sample.After this be positioned on travelling belt 132 input ends and sent into lucifuge constant temperature cover 131 by the abbreviation of the strip box behind application of sample reaction box by travelling belt 132.Need to prove at this, travelling belt 132 is by step motor control, the step distance of stepper motor and stepped intervals time are preestablished by control module, make reaction box be incubated in lucifuge constant temperature cover 131 by travelling belt 132 it to be sent into detection part 133 when reacting completely to detect accordingly.After 133 pairs of reaction boxes of detection part detect and finish, by the outlet of pick-up unit 133 reaction box is sent in the discarded case.Move forward the position of a step-length when reaction tray after, 111 times clean-out openings of sample needle 112 clean, and wait for the order of the application of sample again that is sent by control module.When if certain sample to be checked need be done multinomial test by different types of strip box, sample needle 111 can not clean, provide unit 12 to provide different types of strip box according to preestablishing by control module control reagent, again by the continuous application of sample of sample needle 111 difference, move forward successively and be called for short reaction box by the strip box behind the application of sample, until the detection of finishing according to predefined all samples to be checked.Reaction tray is rotated according to fixing step-length node, in operational process as after any warning occurring and causing travelling belt 132 operations to suspend, start the node number of accumulating the waiting period that the node clocking capability calculating automatically by control module, that also namely incurs loss through delay answers the application of sample number or claims gap digit.After treating that operating personnel check, fix a breakdown and press down acknowledgement key, reaction tray is pressed node and is recovered action, the gap digit incured loss through delay of fast moving at first, be that travelling belt 132 is walked the sky barrel of not adding an examination of, this measure purpose be guarantee the front the strip box of application of sample be that reaction tray is covered the incubation time at preset timed intervals and finished reaction in order in time detect.Travelling belt 132 continues and then runs well then.
When full-automatic immunochromatographiassays assays instrument of the present invention takes place in following situation, can send acoustic alarm by alarm unit, travelling belt 132 suspends mobile simultaneously.
The strip box has strip the implementation of supply measurement signal, as does not have this signal, and alarm unit has sent acoustic alarm and shown " please check strip supply with ", and sample needle 111 suspends application of samples simultaneously, the reaction tray time-out of dividing a word with a hyphen at the end of a line.After treating that operating personnel check, fix a breakdown (expose if any the strip box and then it is pushed up go back to the reagent storehouse, or directly take out the strip box, put back to the reagent storehouse) and press down acknowledgement key, strip pick-up unit of the present invention recovers running by aforementioned principle.
Perhaps, strip box strip is blocked in the reagent storehouse, and in the time of can't supplying with, alarm unit has sent acoustic alarm and shown " please check the reagent storehouse ", and sample needle 111 suspends application of samples simultaneously, the reaction tray time-out of dividing a word with a hyphen at the end of a line.After treating that the operator checks, fixes a breakdown and presses down acknowledgement key, strip pick-up unit of the present invention recovers running by aforementioned principle.
Or, the reagent storehouse is empty, when no strip box is supplied with, alarm unit has sent acoustic alarm and has shown " please replenish the strip box ", sample needle 111 suspends application of sample, reaction tray continues to divide a word with a hyphen at the end of a line by node, treats that the operator presses down Pause key, and reaction tray is suspended mobile, after waiting to replenish the strip box and pressing down the continuation key, strip pick-up unit of the present invention recovers running by aforementioned principle.
Those of ordinary skill in the art will be appreciated that, above embodiment illustrates purpose of the present invention, and be not as limitation of the invention, as long as in essential scope of the present invention, all will drop in the scope of claim of the present invention variation, the modification of the above embodiment.

Claims (12)

1. a full-automatic immunochromatographiassays assays instrument comprises that control module, sampling unit, reagent provide unit and incubation transmission detecting unit, and described control module provides unit and incubation transmission detecting unit to be connected with sampling unit, reagent respectively; Described reagent provides the unit to be connected mutually with the input end level of incubation transmission detecting unit; It is characterized in that:
Described reagent provides the unit to comprise strip box, rotating disc, reagent storehouse and push mechanism, and described rotating disc, reagent storehouse and push mechanism all are connected with control module; Described reagent storehouse is provided with the strip box of single kind from top to bottom along circumferentially evenly being located on the rotating disc at interval in the single reagent storehouse; The horizontal level of described reagent storehouse base plate is consistent with the horizontal level of described incubation transmission detecting unit input end, the base plate upper edge axis in reagent storehouse is provided with gathering sill, the front shroud lower end in reagent storehouse is provided with opening, the shape of opening is corresponding with the shape of strip box xsect, the back shroud lower end in reagent storehouse is provided with pilot hole, and described pilot hole and opening are connected with gathering sill respectively; Described push mechanism is located at the rear in the reagent storehouse that is connected mutually with incubation transmission detecting unit input end and gathering sill and pilot hole by this reagent storehouse are connected mutually with the strip box.
2. full-automatic immunochromatographiassays assays instrument according to claim 1 is characterized in that: described push mechanism employing promotion structure or employing hooking structure.
3. full-automatic immunochromatographiassays assays instrument according to claim 2 is characterized in that, when push mechanism adopted the promotion structure, its concrete structure was any one in following four kinds:
Described push mechanism comprises pusher arm, driving-belt and motor, and described driving-belt is connected with motor and pusher arm respectively, and the xsect of described pusher arm can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises pusher arm, screw rod and motor, and described motor links to each other with an end of screw rod, and screw rod also is connected with pusher arm; The xsect of described pusher arm can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises electromagnet, permanent magnet, slide rail and pusher arm, described electromagnet is located at the two ends of slide rail respectively, the lower end of described pusher arm is sheathed on the outside of slide rail, and the both sides, lower end of described pusher arm are provided with permanent magnet, and described permanent magnet is relative with electromagnet; The xsect of described pusher arm can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises pusher arm, gear bar and the motor that has gear, and described pusher arm is located at the top of gear bar and is fixedlyed connected with the gear bar, and described gear bar also meshes with gear; The xsect of described pusher arm can stretch into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box.
4. full-automatic immunochromatographiassays assays instrument according to claim 3, it is characterized in that: described pilot hole is strip structure, and pilot hole and gathering sill are perpendicular.
5. full-automatic immunochromatographiassays assays instrument according to claim 2 is characterized in that, when push mechanism adopted hooking structure, its concrete structure was any one in following four kinds:
Described push mechanism comprises pusher arm, driving-belt and motor, described driving-belt is connected with motor and pusher arm respectively, the outer end of described pusher arm is hook-shape structure, and the inboard of described hook-shape structure can be stretched into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises pusher arm, screw rod and motor, and described motor links to each other with an end of screw rod, and screw rod also is connected with pusher arm; The outer end of described pusher arm is hook-shape structure, and the inboard of described hook-shape structure can be stretched into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises electromagnet, permanent magnet, slide rail and pusher arm, described electromagnet is located at the two ends of slide rail respectively, the lower end of described pusher arm is sheathed on the outside of slide rail, and the both sides, lower end of described pusher arm are provided with permanent magnet, and described permanent magnet is relative with electromagnet; The outer end of described pusher arm is hook-shape structure, and the inboard of described hook-shape structure can be stretched into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Described push mechanism comprises pusher arm, gear bar and the motor that has gear, and described pusher arm is located at the top of gear bar and is fixedlyed connected with the gear bar, and described gear bar also meshes with gear; The outer end of described pusher arm is hook-shape structure, and the inboard of described hook-shape structure can be stretched into the gathering sill in reagent storehouse and pilot hole and be connected mutually with the strip box;
Wherein said pilot hole is strip structure, and pilot hole and gathering sill are perpendicular.
6. full-automatic immunochromatographiassays assays instrument according to claim 1 is characterized in that: the kind of described strip box is one or more.
7. full-automatic immunochromatographiassays assays instrument according to claim 1 is characterized in that: described incubation transmission detecting unit comprises lucifuge constant temperature cover, travelling belt and detection part, and the output terminal of described travelling belt is connected with the input end of detection part; Described lucifuge constant temperature covers at the periphery, input end rear of travelling belt and the periphery of detection part.
8. full-automatic immunochromatographiassays assays instrument according to claim 7 is characterized in that: described detection part comprises the excitation light source/emission light-receiving, visible light source/visible light receives and visible light source/CCD photographed images one or more in analyzing.
9. full-automatic immunochromatographiassays assays instrument according to claim 7 is characterized in that: described incubation transmission detecting unit employing chain delivery structure or circumference formula transfer structure.
10. full-automatic immunochromatographiassays assays instrument according to claim 1, it is characterized in that: described sampling unit comprises sample needle and clean-out opening, and the sampled signal that described sample needle receives control module is added to sample to be checked in the strip box that is positioned at incubation transmission detecting unit input end; Described sample needle also receives the purge signal of described control module and sample needle is stretched into clean-out opening.
11. according to each described full-automatic immunochromatographiassays assays instrument in the claim 1 to 10, it is characterized in that: described full-automatic immunochromatographiassays assays instrument also comprises quantitative charger, described quantitative charger is connected with control module, quantitative charger is located in the incubation transmission detecting unit, and is connected with the medium position of incubation transmission detecting unit.
12. full-automatic immunochromatographiassays assays instrument according to claim 11 is characterized in that: described full-automatic immunochromatographiassays assays instrument also comprises alarm unit, and described alarm unit is connected with control module.
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