CN102178523B

CN102178523B - Intracranially embedded insulating electrode for experiment

Info

Publication number: CN102178523B
Application number: CN201110096677A
Authority: CN
Inventors: 吴广延; 李轩; 隋建峰
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-04-18
Filing date: 2011-04-18
Publication date: 2012-08-29
Anticipated expiration: 2031-04-18
Also published as: CN102178523A

Abstract

The invention discloses an intracranially embedded insulating electrode for experiment, which is used for behavioral and electrophysiological study and comprises an insulating electrode wire, the lower end of which is the tip of the electrode, and a plurality of folded exposed section electrode wires, the lower ends of which are connected with the upper end of the insulating electrode wire, wherein a thin PE tube is sleeved at the lower part of the exposed section electrode wires and the upper end of the insulating electrode wire; a copper wire is uniformly wound on the upper part of the exposed section electrode wires and the winding part of the copper wire is an electrode clamping part; a thick PE tube, with the lower end being on a level with the lower end of the thin PE tube, is sleeved on the thin PE tube and the exposed section electrode wires, and the upper end of the thick PE tube is on a level with the lower end of the electrode clamping part. The intracranially embedded insulating electrode for experiment is simple in manufacturing, low in cost and convenient in use.

Description

Experiment is with the embedding insulating electrode of intracranial

Technical field

The invention belongs to behavior electrophysiologic study instrument and equipment technical field, be specifically related to a kind of experiment with the embedding insulating electrode of intracranial.

Background technology

In neuroscience and psychological study field, often need carry out behavior electrophysiologic study (in the body experiment), the stimulation in the record He Nao district that a wherein very important research is the brain cell electrical activity, and want chronic and dynamic observe electrophysiological index continuously.The eletrode tip and the electrode clamping part of the embedding insulating electrode that this just requires to use have good electrical conductivity, and electrode body (being that embedding insulating electrode is removed the part outside eletrode tip and the electrode clamping part) has good insulation performance property, and stability maintenance is high.

Existing embedding insulating electrode is the retaining part of end welding at the insulated electro polar filament.The appearance insullac of its insulated electro polar filament is destroyed in welding process easily; Influence the insulating properties of electrode body; And the retaining part of welding is easy in the animal feeding process, come off with the electrode that is embedded in the animal crown, is unfavorable for the long-term raising of animal and the observation of chronic and continuous dynamic electrophysiological index.

Summary of the invention

The purpose of this invention is to provide a kind of experiment with the embedding insulating electrode of intracranial; It can not only write down the brain cell electrical activity and stimulate brain kernel group; And eletrode tip and electrode clamping part have good electrical conductivity, and electrode body has good insulation performance property, and can held stationary.

Experiment of the present invention comprises that with the embedding insulating electrode of intracranial the lower end is the insulated electro polar filament of eletrode tip, the naked section wire electrode that is folded into multiply that the lower end is connected with insulated electro polar filament upper end, wherein:

One thin PE pipe box is in the bottom of said naked section wire electrode and the upper end of insulated electro polar filament;

One copper wire is wrapped in the top of said naked section wire electrode uniformly, and the part that this copper wire twines is the electrode clamping part;

One thick PE pipe lower end is concordant with thin PE pipe lower end and be enclosed within on thin PE pipe and the naked section wire electrode, and upper end and electrode clamping subordinate that this thick PE manages hold level with both hands together.

Further, also be wound with the copper wire that is beneficial to firm naked section wire electrode and increase electric conductivity on the naked section wire electrode in the said thick PE pipe.

Further, said thick PE pipe be bent into first vertically the section pipe, with first vertically the horizontal segment pipe that is connected of section pipe upper end, second vertical three sections of the section pipes that are connected with horizontal segment pipe right-hand member, said first vertical section length of managing equals the length that thin PE manages.

Further, be filled with sealing glue in the gap between said thick PE pipe, thin PE pipe, naked section wire electrode bottom and insulated electro polar filament upper end.

Further, said naked section wire electrode is to be folded into three strands bare electrode silk.

Naked section wire electrode of the present invention is after folding and twine copper wire, has increased the electric conductivity of insulating electrode retaining part and the fastness of clamping; The thick PE pipe that is enclosed within naked section wire electrode outside and thin PE pipe have not only increased the insulating properties of the electrode body of embedding insulating electrode, and its thick PE pipe and thin PE tube edges are as the reference point of insulated electro polar filament in intracranial length; The sealing glue of filling in the gap between thick PE pipe, thin PE pipe, naked section wire electrode bottom and insulated electro polar filament upper end has increased the fastness that connects between them; Thick PE pipe is bent into three sections, has increased embedding insulating electrode fixation stability property in use.This embedding insulating electrode is manufactured simply, and cost is low, and is easy to use, is applicable to the acute and chronic experiment of brain research and the dynamically observation of electrophysiological index continuously.

Description of drawings

Fig. 1 is a structural representation of the present invention.

Fig. 2 is the sketch map of the present invention when user mode.

Among the figure: 1. insulated electro polar filament; 2. naked section wire electrode; 3. copper wire; 4. thin PE pipe; 51. thick PE pipe first is the section pipe vertically; 52. thick PE pipe horizontal segment pipe; 53. thick PE pipe second is the section pipe vertically; 6. eletrode tip; 7. electrode clamping part; 8. sealing glue; 9. dentistry cement 10. skull surface.

The specific embodiment

Below in conjunction with accompanying drawing the present invention is described further.

Experiment as shown in Figure 1 is with the embedding insulating electrode of intracranial, comprise the lower end be naked section wire electrode 2 after folding of the insulated electro polar filament 1 of eletrode tip 6, three stock-traders' know-hows that the lower end is connected with insulated electro polar filament 1 upper end, be enclosed within the thin PE pipe 4 of naked section wire electrode 2 bottoms and insulated electro polar filament 1 upper end, the copper wire 3, lower end and the thin PE that are wrapped in said naked section wire electrode 2 tops uniformly manage the concordant and thick PE that be enclosed within on thin PE pipe 4 and the naked section wire electrode 2 in 4 lower ends and manage 5; The part on naked section wire electrode 2 tops that copper wire 3 twines is an electrode clamping part 7, and the upper end of thick PE pipe 5 is concordant with electrode clamping part 7 lower ends.

In order to make naked section wire electrode 2 fixing-stables, also be wound with on the naked section wire electrode 2 in thick PE pipe 5 and be beneficial to fixedly naked section wire electrode 2 and the copper wire that increases electric conductivity.

In order to increase embedding insulating electrode fixation stability property in the observation of the long-term raising of animal and chronic and continuous dynamically electrophysiological index; Thick PE pipe 5 be bent into first vertically section pipe 51, with first vertically the horizontal segment pipe 52 that is connected of section pipe upper end, second vertical 53 3 sections of the section pipes that are connected with horizontal segment pipe right-hand member, and first vertical section managed 51 length and equal thin PE and manage 4 length.

In order to increase the fastness that connects between thick PE pipe 5, thin PE pipe 4, naked section wire electrode 2 bottoms and insulated electro polar filament 1 upper end and the insulating properties of electrode body, filling sealing glue 8 in the gap between thick PE pipe 5, thin PE pipe 4 and naked section wire electrode 2 bottoms and insulated electro polar filament 1 upper end.

Manufacturing process of the present invention is following: (following concrete data just illustrate, and do not represent qualification of the present invention, and it is by the decision of the depth of the size of animal and record or stimulation location in actual fabrication)

Divest the appearance insullac of insulated electro polar filament (length is a 13.0-14.0 cm) end, form naked section wire electrode (length is 10.0-11.0 cm), the naked section wire electrode is folded into three strands;

Then one section copper wire 3 (diameter is 0.5 mm, and length is 15.0-20.0 cm) evenly closely is wrapped on three strands of folding wire electrodes, respectively stays one section exposed three strands of wire electrode at the two ends of these three strands of wire electrodes;

(internal diameter is 0.6 mm with a thin PE pipe 4; External diameter is 1.1 mm; Length is 0.3-0.4 cm) entangle the bottom (promptly near exposed three strands of wire electrodes of insulated electro polar filament 1 one ends) of naked section wire electrode 2 and the upper end (length is 1.0-1.5 mm) of insulated electro polar filament 1; Again thick PE pipe 5 (internal diameter is 1.8 mm, and external diameter is 2.4 mm, and length is 2.0-2.5 cm) are entangled the copper wire 3 of thin PE pipe 4 and part winding; The naked section wire electrode that another part twines copper wire 3 is electrode clamping part 7, and thickness PE tube edges is concordant.

Embedding insulating electrode is converted into 90 ° with the copper wire edge (being the upper end of thin PE pipe 4) near insulated electro polar filament 1, and insulated electro polar filament 2 opisthotonos with copper wire 3 and parcel become 90 ° again; At last with the gap between the upper end of the thick PE pipe of glue 8 sealings, thin PE pipe, naked section wire electrode bottom and insulated electro polar filament 1.

As shown in Figure 2, in use, treating excess syndrome is tested animal (rat, Cavia porcellus, rabbit etc.) and is fixed on the brain solid positioner.According to the location in the brain district that will write down or stimulate, confirm length under the thickness PE tube edges of embedding insulating electrode, bore a duck eye in the shadow-mark district of the skull surface 10 in this brain district, insulated electro polar filament 1 is vertically inserted from this duck eye.At last with dentistry cement 9 fixing should experiments with the embedding insulating electrode of intracranial.

Claims

1. an experiment comprises that with the embedding insulating electrode of intracranial the lower end is insulated electro polar filament (1), the lower end and the naked section wire electrode (2) that is folded into multiply that insulated electro polar filament upper end is connected of eletrode tip (6), is characterized in that:

One thin PE pipe (4) is enclosed within the bottom of said naked section wire electrode and the upper end of insulated electro polar filament;

One copper wire (3) is wrapped in the top of said naked section wire electrode uniformly, and the part that this copper wire twines is electrode clamping part (7);

One thick PE pipe (5) lower end concordant with thin PE pipe lower end and be enclosed within that thin PE manages and the naked section wire electrode on; The upper end and the electrode clamping subordinate of this thick PE pipe hold level with both hands together; And thick PE pipe (5) be bent into first vertically section pipe (51), with first vertically the horizontal segment pipe (52) that is connected of section pipe upper end, second vertical (53) three sections of the section pipes that are connected with horizontal segment pipe right-hand member, said first vertical section length of managing equals the length that thin PE manages.

2. experiment according to claim 1 is characterized in that with the embedding insulating electrode of intracranial: also be wound with copper wire (3) on the said naked section wire electrode (2) in the said thick PE pipe (5).

3. experiment according to claim 1 and 2 is characterized in that with the embedding insulating electrode of intracranial: all be filled with sealing glue (8) in gap between said thick PE pipe (5) and thin PE pipe (4) and the gap between thin PE pipe (4) and naked section wire electrode (2) bottom.

4. experiment according to claim 1 and 2 is characterized in that with the embedding insulating electrode of intracranial: said naked section wire electrode (2) is for being folded into three strands bare electrode silk.