CN102068268A - Method for utilizing multi-energy X-ray composite projection to digitally synthesize images and system thereof - Google Patents

Method for utilizing multi-energy X-ray composite projection to digitally synthesize images and system thereof Download PDF

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CN102068268A
CN102068268A CN 201010592939 CN201010592939A CN102068268A CN 102068268 A CN102068268 A CN 102068268A CN 201010592939 CN201010592939 CN 201010592939 CN 201010592939 A CN201010592939 A CN 201010592939A CN 102068268 A CN102068268 A CN 102068268A
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CN102068268B (en
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陈建锋
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Zhejiang Kangyuan Medical Device Co., Ltd.
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Abstract

The invention discloses a method for utilizing multi-energy X-ray composite projection to digitally synthesize images. The method sequentially includes the following steps: (A) projected image signal acquisition: n X rays with different energies are adopted to respectively project s image signals on m different spatial positions, wherein n is larger than or equal to 1, m is larger than or equal to 1, and n multiplied by m is s; (B) projected image preprocessing: analog projected image signals are first amplified and converted into digital image signals by a signal amplifier and an analog-to-digital converter; the digital image signals are then inputted into a digital image preprocessor; and the digital image preprocessor compensates the sensitivity of each received pixel unit; (C) projected digital image synthesis: by utilizing digital image processing, a digital image synthesizer synchronizes the amended digital images into a series of synchronized digital images; (D) synchronized digital images post-processing: the requirements of diagnosis can be met; and (E) the output of the synchronized digital images: the processed images are outputted to a terminal device.

Description

A kind of method and device thereof that utilizes multipotency X ray compound-projection numeral compound imaging
Technical field
The present invention relates to digital X-ray image compound imaging application, relate in particular to a kind of synthetic method of multipotency X ray compound-projection digital image and device of utilizing.
Background technology
Because digital X-ray line photography (DR-Digital Radiography) has the following advantages with respect to film X-ray line photography: the radiation dose that improves medical diagnosis on disease efficient and minimizing patient, and do not have an environmental pollution, need with film with and relevant chemical raw material.On overall, digital X-ray line photography is technical digital implementation and the digital image processing techniques utilized at traditional projection X-ray line photography.Digital X-ray line photography as a kind of be that it is made up of three parts usually: first is an X-ray source at projection X-ray line photography, comprise X-ray tube and relevant high voltage control circuit.Second portion is the X-line receiver, and two kinds of receive modes are arranged usually, and a kind of is that CCD (Charged-Coupled Devices) receives, and another kind is that quasiconductor flat board (Flat Panel Detectors) receives.CCD (Charged-Coupled Devices) receptor at first converts the X-ray to visible light by a change-over panel (CsI) with it, and these visible lights just can be focused the CCD chip surface then, and are absorbed by it.The CCD chip is made up of one group of isolating semiconductor silicon integrating circuit or unit, and for example: the CCD chip of a 2.5x2.5cm can contain 1024x1024 circuit unit.To produce electronics after visible light is absorbed by the CCD chip surface and be stored on each unit, the power of light and electron number are directly proportional.These electronics can be read out with the pattern of row output then.For the giant-screen receptor, need a point-device optical focusing lens that it is projected to the less CCD surface of relative area.Contain on the dull and stereotyped receptor of the quasiconductor surface and much independently accept the unit.Each unit can convert the X-ray of its acceptance to the signal of telecommunication, then the mode of these signals of telecommunication with serial level and vertical line will be read out.The CCD receptor is relatively lower with the dull and stereotyped receptor cost of quasiconductor, but owing to it contains an optical focusing system, so its image resolution ratio and signal to noise ratio are lower, and volume is bigger.Third part is that data image signal is handled and pictorial display.For traditional film roentgenograph X art, digital X-ray line photography imaging has bigger dynamic indication range, and DR can make full use of the modern computer image processing techniques simultaneously, to realize best diagnosis effect.Based on digital X-ray line photography system, constantly develop the application technology that renewal in recent years: dual energy photography (Dual-energyRadiography), digital fault plane synthetic technology (Digital Tomosynthesis) or the like.By these new The Application of Technology, make medical clinic applications more accurate.
The dual energy photography has been widely used in the angiography of X ray fluorescent screen.Because special electronics constraint efficiency should, the X ray absorption spectra of x-ray imaging agent material (as iodine, barium etc.) some energy section (~33keV) X-ray absorption coefficient of sudden change arranged, but the X-ray absorption coefficient of the tissue of human body does not have such sudden change in this energy section.The characteristics of utilizing these different X ray to absorb, we can produce two frame radioscopic images, and a frame is produced by the relative low-energy X-ray before the absorptance sudden change, and another frame is produced by the relative high-energy X ray after the absorptance sudden change.Then this two frame of digital image is weighted linear combination, just can gets the radioscopic image that only contains contrast agent material.If contrast agent material only is contained in the blood of some blood vessel, we just can utilize it to diagnose the physiological function of blood vessel and near organ thereof.
Also have a kind of mode to be: in digital X-ray line photography imaging process, because different property (effective atomic number of soft tissue: Z=7.6, the effective atomic number of osseous tissue: Z=13) of the effective atomic number of interior soft tissue of human body and osseous tissue.(~50kVp) section, the X-gamma ray absorption coefficient is directly relevant with atomic number Z: with Z^3 proportional (mainly being photoelectric effect) low-yield.(~120kVp) section, X-gamma ray absorption coefficient and atomic number Z be pass (mainly being Compton effect) not and at high-energy.Be similar to double energy X-ray fluorescent screen angiography, we can produce two two field pictures, a frame be by low-yield relatively X-ray produce (~50kVp), another frame then be by relative high-energy X-ray produce (~120kVp).Then this two two field picture is weighted linear combination, just can be only contained two frame radioscopic images of soft tissue (as the lung organ) or skeletal tissue's (as thoracic bone).
Although the dual energy method obtains in single projection imaging and should have, as X ray fluorescent screen angiography, it is also not accomplished in other imaging system, as aspect the digital fault plane compound imaging (DigitalTomosynthesis)." digital fault plane compound imaging " is a kind of new formation method.This technology and method will improve " contrast resolution " of image effectively, thereby can diagnose out the minor variations of the structure of matter effectively." fault plane compound imaging " is based on to blur and focusing on the projected image of fault plane with external structure, and the technology of preserving the projected image of the structure on the focusing surface.Up to the present, digital fault plane synthetic technology only utilizes the method for single energy to realize, and this technology is mainly used in the breast imaging system.Roundel is positioned at the focusing surface top, and square thing is arranged in focusing surface, and delta is positioned at the focusing surface below.When we with x-ray source when leftward position A moves to right positions B, the picture of X ray projection " A " and " B " also will change.In projection image " A ", the picture of left, middle and right is respectively " delta ", " square thing " and " roundel ".And in projection image " B ", the picture of left, middle and right is respectively " roundel ", " square thing " and " delta ".
Provided the image of these two projections, and the image of these two projections has been carried out simple linear, additive.We can see from the image of addition: being projected in the image after synthetic of roundel and delta, to be blured owing to be distributed in the left and right sides, and being projected in the image after synthetic of square thing is positioned at same position all the time and is retained.
Along with the continuous development of computer technology, the fault plane that traditional fault plane synthetic technology has been further extended numeral synthesizes in recent years.Adopt similar notion, when we move to position " B " with X-ray source from left-most position " A ", when " C " and " D " (right-most position), X ray projection imaging " A ", " B ", " C " and " D " also will change.We carry out in various degree translation and simple linear combination with these four groups of images, just can obtain four new two field pictures.Every two field picture will keep the projection of the structure of certain specific fault plane, and blurs the projection of the structure of other aspect.Like this, finally we will obtain the image of the projection of a series of fault plane structures.These images can be used to clinical diagnosis these fault plane structure and characteristics thereof.The fault plane synthetic technology can make us see the structure that can't see in traditional projection imaging.
Because continuing to bring out of these advanced digital X-ray photography systems and technology makes that doctors can diagnose out the early stage pathological changes of patient more exactly clinically.Advantages such as simultaneously these advanced digital X-ray photography systems compare with traditional CT, can also keep cheap relatively cost, and are easy to use, and X-radiation dosage is low.This patent invention will further develop these new techniques, with the fault plane formation method of the single energy of existing digital X-ray photography and fault plane imaging method and the equipment that equipment further develops multipotency.
Summary of the invention
The object of the present invention is to provide a kind of method and device thereof that utilizes multipotency X ray compound-projection numeral compound imaging, can solve existing monoergic imaging technique definition deficiency effectively, can not distinguish the problems such as structure of different tissues effectively, realize that the sensitivity and the degree of accuracy of diagnostic imaging significantly improves.
In order to solve the problems of the technologies described above, the present invention adopts following technical scheme:
A kind of method of utilizing multipotency X ray compound-projection numeral compound imaging is characterized in that in turn including the following steps:
The collection of A, projection image signal: adopt the X ray of n part different-energy to go out s part picture signal, n 〉=1, m 〉=1, s=n * m m different spatial projection respectively;
The pre-treatment of B, projected image: the projected image analogue signal is at first passed through signal amplifier and analog-digital converter, the projected image analogue signal is amplified and converts data image signal to; Then data image signal is input to the digital picture pre-treating device; The digital picture pre-treating device is done compensation to the pixel cell sensitivity of each reception;
Synthesizing of C, projection digital picture: the digital picture of revising is passed through the digital picture synthesizer, utilize Digital Image Processing, synthesize a series of composite number word image;
The post processing of D, composite number word image: to satisfy the requirement of diagnosis;
The output of E, composite number word image: will handle the back image and export terminal unit to.
Preferably, steps A adopts n part different-energy to carry out projection at other (m-1) individual different spaces projected position for the X ray that adopts n part different-energy earlier goes out n part image in a setting space position projection respectively again, i.e. projection produces s=n * m part image, n 〉=1, m 〉=1.
Preferred, steps A goes out two parts of images in a setting space position projection respectively for adopting the X ray of two parts of different-energies earlier, adopt two parts of different-energies to carry out projection at other (m-1) individual different spaces projected position again, i.e. projection produces s=2m part image, m 〉=1.
Preferably, steps A goes out m part image for adopting an X ray of setting energy earlier m locus projection, adopts the X ray of other (n-1) part different-energy to carry out projection respectively m position again, i.e. projection produces s=n * m part image, n 〉=1, m 〉=1.
Preferred, steps A goes out m part image for adopting an X ray of setting energy earlier m locus projection, adopts the X ray of another part different-energy to carry out projection m position again, i.e. projection produces s=2m part image, m 〉=1.
Preferably, the method that compensation is done in sensitivity to pixel cell among the step B is with a uniform X ray direct irradiation receptor, adjusts the gain of each pixel cell, makes from the picture signal of the same intensity of each pixel cell output.
Preferably, the digital picture pre-treating device also will be utilized the physical characteristic and the approximate hypothesis of scattered x-ray among the step B, scattered x-ray be disturbed to received signal do correction.
Preferred, the method for correction is that scattered x-ray is evenly distributed on each regional area, and the decay of its scattering strength and each regional area X ray is proportional or proportional with the thickness of the tissue of the regional area that passes through.
Further, the digital picture pre-treating device also will be done the motion correction of projection digital picture among the step B, comprise the correction of human external motion to the image influence, to obtain the projection digital picture of moving displacement correction.
Preferably, the human external motion utilizes optical inductor people from location displacement body to being modified to of image influence, solves the displacement of human external structure relative motion.
Preferably, the human external motion is carried out Flame Image Process and image comparison to being modified to by the projected image to the human external feature structure of image influence, solves the displacement of human external structure relative motion.
Further, the digital picture pre-treating device also will be done the motion correction of projection digital picture among the step B, comprise the correction of inside of human body motion to the image influence, to obtain the projection digital picture of moving displacement correction.
Preferably, the inside of human body motion is to the cycle movement displacement that the signal that utilizes electrocardiograph is located inside of human body that is modified to of image influence, the signal of electrocardiograph can provide the periodic phase information of heartbeat, in identical phase place identical heartbeat displacement is arranged, solve the displacement of inside of human body relative motion.
Preferably, the inside of human body motion is carried out Flame Image Process and image comparison to being modified to by the projected image to the inside of human body structure of image influence, the relative motion of human organ border or shape of blood vessel feature defines inside of human body structure relative motion, solves the displacement of inside of human body structure relative motion.
Preferably, among the step C synthesize earlier every same space angle but a fixed weighted linear combination is adopted in projection with different-energy earlier, to obtain the projection image of organ-/ tissue composition, projection image with the organ-/ tissue of all projection angles makes up then, thereby produces one group of image that contains the fault plane structure of organ-/ tissue composition.
Preferably, a projection image that sets the different angles of energy is synthesized in synthesizing earlier among the step C, to obtain organizing the image of fault plane structure; Image with the formed fault plane of different-energy adopts weighting translation linear combination then, thereby obtains the image of organ-/ tissue composition fault plane structure.
Preferably, post processing comprises that the dynamic compression, the reduction of dynamic image noise, image-region selection, figure image intensifying, dynamic image of digital picture show among the step D, obtains the image after a series of processing.
A kind of device that is used for realizing utilizing the method for multipotency X ray compound-projection numeral compound imaging as claim 1, it is characterized in that: comprise x-ray source and picture receiver, picture receiver connects amplifier, analog-digital converter, digital projection picture pre-treating device, interim digital projection picture memorizer, Digital Image Processing and synthesizer, digital composograph preprocessor and digital composograph memorizer successively, and digital composograph memorizer connects final image display or computer network output.
Further, x-ray source connects x-ray source high-frequency and high-voltage control circuit and x-ray source position control circuit, picture receiver connects the receptor control circuit, and x-ray source high-frequency and high-voltage control circuit, x-ray source position control circuit, receptor control circuit, Digital Image Processing and synthesizer, digital composograph preprocessor, digital composograph memorizer, final image display all connect terminal use's controller.
The present invention has following beneficial effect owing to adopted technique scheme:
The different X ray absorption characteristic that the present invention is mainly had in different energy sections X ray in conjunction with the human body different tissues, carrying out numeral with the digital picture of different spaces angle projection synthesizes, finally obtain a series of high-contrasts, highly sensitive medical image, these images will comprise the surface information that is broken into of different material composition, can make the doctor diagnose the state of an illness more exactly.
The present invention is broken into scanning technique (CT-Computerized Tomography) with computer and compares, and has simple in structurely, and cost is low, and is easy to use, the advantage that X-radiation dosage is little.
The present invention can be applied to medical imaging, safety check instrument etc., also method of the present invention can be applied to the exploitation of breast machine and other specialized imaging of medical instruments.
Description of drawings
The invention will be further described below in conjunction with accompanying drawing:
Fig. 1 utilizes the flow chart of the method for multipotency X ray compound-projection numeral compound imaging for the present invention is a kind of;
Fig. 2 utilizes the structured flowchart of multipotency X ray compound-projection numeral compound imaging device for the present invention is a kind of.
The specific embodiment
As shown in Figure 1, a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging of the present invention in turn includes the following steps:
The collection of A, projection image signal: adopt the X ray of n part different-energy to go out s part picture signal, n 〉=1, m 〉=1, s=n * m m different spatial projection respectively.The collection of projection image signal can be adopted following method: adopt the X ray of n part different-energy to go out n part image in a setting space position projection respectively earlier, adopt n part different-energy to carry out projection again at other (m-1) individual different spaces projected position, be that projection produces s=n * m part image, n 〉=1, m 〉=1.Preferred, the collection of projection image signal goes out two parts of images in a setting space position projection respectively for adopting the X ray of two parts of different-energies earlier, adopt two parts of different-energies to carry out projection at other (m-1) individual different spaces projected position again, i.e. projection produces s=2m part image, m 〉=1.The collection of projection image signal also can be adopted following method: adopt an X ray of setting energy to go out m part image m locus projection earlier, adopt the X ray of other (n-1) part different-energy to carry out projection m position respectively again, be that projection produces s=n * m part image, n 〉=1, m 〉=1.Preferred, steps A goes out m part image for adopting an X ray of setting energy earlier m locus projection, adopts the X ray of another part different-energy to carry out projection m position again, i.e. projection produces s=2m part image, m 〉=1.Be the collection of multipotency and multi-angle space projection image, a kind of method is: we can adopt a fixed X ray energy (for example low-yield or high-energy) earlier and change the space angle projection to obtain one group of projected image; Change the X ray energy then, the complex phase of laying equal stress on space angle position together projection again obtains another group projected image.Another kind method is: we can adopt a fixed space angle to come to obtain two frame projected images with different X ray energy (for example low-yield and high-energy) projections earlier; Change the space angle position then, come to finish the projection of all space angles at last to obtain two frame projected images in addition and repeat identical X ray energy (low-yield and high-energy) projection.Similarly, we can replace dual energy with multipotency generally speaking.For example: adopt the X ray of 2 parts of different-energies to go out 2 parts of images the 1st fixed space position projection respectively earlier, adopt the X ray of 2 parts of different-energies to go out 2 parts of images the 2nd different spatial projection respectively again, adopt the X ray of 2 parts of different-energies to go out 2 parts of images the 3rd different spatial projection respectively again, adopt the X ray of 2 parts of different-energies to go out 2 parts of images the 4th different spatial projection respectively again, obtain 8 parts of images altogether; 2 parts of x rays that energy is different, portion is a high-energy, portion is low-yield.Again for example: adopt high-octane X ray to go out 3 parts of images 3 fixed space position projections respectively earlier, adopt low-energy X ray to go out 3 parts of images in above-mentioned 3 different spatial projections respectively again, obtain 6 parts of different images.
The pre-treatment of B, projected image: the projected image analogue signal is at first passed through signal amplifier and analog-digital converter, the projected image analogue signal is amplified and converts data image signal to; Then data image signal is input to the digital picture pre-treating device; The digital picture pre-treating device is done compensation to the pixel cell sensitivity of each reception and is revised and scattered x-ray disturbed to received signal and do correction.Because the human body imaging process need be finished in the regular hour, the motion of human organ tissue in the meantime is as human body respiration, heartbeat etc., all inevitable.And these athletic meeting produce wrong image information, thereby obtain wrong clinical diagnosis result.Here we will adopt the method for automatic digital picture correction to revise.Compensation correction is done in sensitivity to pixel cell: a kind of simple method is with a uniform X ray direct irradiation receptor, adjusts the gain of each pixel cell, makes from the picture signal of the same intensity of each pixel cell output.We will be according to the physical characteristic of X ray scattering simultaneously, do correction with the X ray scattering is interferential to received signal, the method of revising is that scattered x-ray is evenly distributed on each regional area, and its scattering strength and each regional area X ray are decayed proportional or proportional with the thickness of the tissue of the regional area that passes through.The digital picture pre-treating device also will be done the motion correction of projection digital picture, comprise that human external motion is to the correction of image influence and the inside of human body motion correction to the image influence, to obtain the projection digital picture of moving displacement correction.The human external motion utilizes optical inductor people from location displacement body to being modified to of image influence, solves the displacement of human external structure relative motion.The human external motion also can solve the displacement of human external structure relative motion for carrying out Flame Image Process and image by the projected image to the human external structure relatively to the correction of image influence.The inside of human body motion is to the cycle movement displacement that the signal that utilizes electrocardiograph is located inside of human body that is modified to of image influence, the signal of electrocardiograph can provide the periodic phase information of heartbeat, in identical phase place identical heartbeat displacement is arranged, solve the displacement of inside of human body relative motion.The inside of human body motion also can be for carrying out Flame Image Process and image relatively to the correction of image influence by the projected image to the inside of human body structure, the relative motion of human organ border or shape of blood vessel feature defines inside of human body structure relative motion, solves the displacement of inside of human body structure relative motion.
Synthesizing of C, projection digital picture: the digital picture of revising is passed through the digital picture synthesizer, utilize Digital Image Processing, synthesize a series of composite number word image.The projection digital picture synthesize earlier every same space angle but a fixed weighted linear combination is adopted in projection with different-energy earlier, to obtain the projection image of organ-/ tissue composition, projection image with the organ-/ tissue of all projection angles makes up then, thereby produces one group of image that contains the fault plane structure of organ-/ tissue composition.The synthetic of projection digital picture also can be for earlier a projection image that sets the different angles of energy being synthesized, to obtain organizing the image of fault plane structure; Image with the formed fault plane of different-energy adopts weighting translation linear combination then, thereby obtains the image of organ-/ tissue composition fault plane structure.
The post processing of D, composite number word image: composograph is handled by the digital picture preprocessor, dynamic compression, the reduction of dynamic image noise, image-region selection, figure image intensifying, dynamic image as digital picture show or the like, obtain the image after a series of processing, to satisfy the requirement of diagnosis.
The output of E, composite number word image: will handle the back image and export terminal unit to.
As shown in Figure 2, be a kind of device that is used to realize utilize the method for multipotency X ray compound-projection numeral compound imaging, comprise x-ray source and picture receiver, picture receiver connects amplifier, analog-digital converter (ADC), digital projection picture pre-treating device, interim digital projection picture memorizer, Digital Image Processing and synthesizer (DSP), digital composograph preprocessor and digital composograph memorizer successively, and digital composograph memorizer connects final image display or computer network output.X-ray source connects x-ray source high-frequency and high-voltage control circuit and x-ray source position control circuit, the digital picture receptor connects the receptor control circuit, and x-ray source high-frequency and high-voltage control circuit, x-ray source position control circuit, receptor control circuit, Digital Image Processing and synthesizer, digital composograph preprocessor, digital composograph memorizer, final image display all connect terminal use's controller.
The user can import instruction (parameter) to required x-ray source by " terminal use's controller ": 1) x-ray source high-frequency and high-voltage control circuit: monoergic or multipotency, kVp, mAs/mA, the x-ray source size is (as 0.1mm, 0.3mm or 0.6mm), 2) x-ray source position control circuit: single or multiple position, rotational angle, rotation/translational velocity etc.Concrete gatherer process is such, after x-ray source receives these instructions, at first with a fixed X ray energy (for example 140kVp), rotate radiographic source to form the space projection image of different angles, change X ray energy (for example 70kVp) then, repeat above-mentioned rotation again to form the space projection image of another group different angles.
In this process, the user can pass through " terminal use's controller ", and " accepter " imported instruction (parameter): begin/stop acquired signal, every frame projection image signal is gathered required time, picking rate or the like.The analog picture signal that receives will be by " signal amplifier ", is stored in " projection digital image memory " after " analog-digital converter " and " digital projection picture pre-treating device " temporarily.The user can import instruction (parameter) by " terminal use's controller " then: the image slices face degree of depth (cm), the fault plane number of plies (single or multiple lift face), and organ classification (lungs, skeleton), the digital picture that is stored in " digital projection picture memorizer " lining is synthesized.These synthesize finishes in " Digital Image Processing and synthesizer ".The simplest a kind of synthetic method is: the set of digital images of all projections of a certain specific X ray energy (as the X ray that produces under the 140kVp high pressure) is carried out the processing of simple translation addition.In this building-up process, we can revise automatically to the motion of human body.A kind of simple method is with respect to the do relative motion correction of displacement of first width of cloth projection image of the same space projected position with second width of cloth projection image.
Synthetic later picture signal will be output to " digital picture preprocessor ".The user can pass through " terminal use's controller ", and " preprocessor " imported instruction (parameter): the required time is gathered in interested picture signal scope of composograph and zone." digital picture preprocessor " does corresponding processing with digital picture, selects (Image segmentation), figure image intensifying (Imageenhancement) or the like as dynamic compression (Dynamic compression), dynamic image noise reduction (Dynamicimage noise reduction), the image-region of digital picture.
At last the digital picture of handling well is stored in " digital image memory ".These digital pictures can show in high resolution display, or print, and output to computer network, or on the DVD, are provided with the back diagnosis and use.
Below only be specific embodiments of the invention; but technical characterictic of the present invention is not limited thereto, and is any based on the present invention, for realizing essentially identical technique effect; done the ground simple change, be equal to replacement or modification etc., all be covered by among protection scope of the present invention.

Claims (19)

1. method of utilizing multipotency X ray compound-projection numeral compound imaging is characterized in that in turn including the following steps:
The collection of A, projection image signal: adopt the X ray of n part different-energy to go out s part picture signal, n 〉=1, m 〉=1, s=n * m m different spatial projection respectively;
The pre-treatment of B, projected image: the projected image analogue signal is at first passed through signal amplifier and analog-digital converter, the projected image analogue signal is amplified and converts data image signal to; Then described data image signal is input to the digital picture pre-treating device; The digital picture pre-treating device is done compensation to the pixel cell sensitivity of each reception;
Synthesizing of C, projection digital picture: the digital picture of revising is passed through the digital picture synthesizer, utilize Digital Image Processing, synthesize a series of composite number word image;
The post processing of D, composite number word image: to satisfy the requirement of diagnosis;
The output of E, composite number word image: will handle the back image and export terminal unit to.
2. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 1, it is characterized in that: described steps A goes out n part image in a setting space position projection respectively for the X ray that adopts n part different-energy earlier, adopt described n part different-energy to carry out projection again at other (m-1) individual different spaces projected position, be that projection produces s=n * m part image, n 〉=1, m 〉=1.
3. according to the described a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging of claim 2, it is characterized in that: described steps A goes out two parts of images in a setting space position projection respectively for adopting the X ray of two parts of different-energies earlier, adopt described two parts of different-energies to carry out projection again at other (m-1) individual different spaces projected position, be that projection produces s=2m part image, m 〉=1.
4. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 1, it is characterized in that: described steps A goes out m part image for adopting an X ray of setting energy earlier m locus projection, adopt the X ray of other (n-1) part different-energy to carry out projection in a described m position respectively again, be that projection produces s=n * m part image, n 〉=1, m 〉=1.
5. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 4, it is characterized in that: described steps A goes out m part image for adopting an X ray of setting energy earlier m locus projection, adopt the X ray of another part different-energy to carry out projection again in a described m position, be that projection produces s=2m part image, m 〉=1.
6. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 1, it is characterized in that: the method that compensation is done in sensitivity to pixel cell among the described step B is with a uniform X ray direct irradiation receptor, adjust the gain of each pixel cell, make from the picture signal of the same intensity of each pixel cell output.
7. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 1, it is characterized in that: the digital picture pre-treating device also will be utilized the physical characteristic and the approximate hypothesis of scattered x-ray among the described step B, scattered x-ray be disturbed to received signal do correction.
8. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 7, it is characterized in that: the method for described correction is that scattered x-ray is evenly distributed on each regional area, and the decay of its scattering strength and each regional area X ray is proportional or proportional with the thickness of the tissue of the regional area that passes through.
9. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 1, it is characterized in that: the digital picture pre-treating device also will be done the motion correction of projection digital picture among the described step B, comprise the correction of human external motion, to obtain the projection digital picture of moving displacement correction to the image influence.
10. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 9, it is characterized in that: described human external motion utilizes optical inductor people from location displacement body to being modified to of image influence, solves the displacement of human external structure relative motion.
11. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 9, it is characterized in that: described human external motion is carried out Flame Image Process and image comparison to being modified to by the projected image to the human external feature structure of image influence, solves the displacement of human external structure relative motion.
12. according to claim 1 or 9 described a kind of methods of utilizing multipotency X ray compound-projection numeral compound imaging, it is characterized in that: the digital picture pre-treating device also will be done the motion correction of projection digital picture among the described step B, comprise the correction of inside of human body motion, to obtain the projection digital picture of moving displacement correction to the image influence.
13. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 12, it is characterized in that: described inside of human body motion is to the cycle movement displacement that the signal that utilizes electrocardiograph is located inside of human body that is modified to of image influence, the signal of electrocardiograph can provide the periodic phase information of heartbeat, in identical phase place identical heartbeat displacement is arranged, solve the displacement of inside of human body relative motion.
14. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 12, it is characterized in that: described inside of human body motion is carried out Flame Image Process and image comparison to being modified to by the projected image to the inside of human body structure of image influence, the relative motion of human organ border or shape of blood vessel feature defines inside of human body structure relative motion, solves the displacement of inside of human body structure relative motion.
15. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 1, it is characterized in that: among the described step C synthesize earlier every same space angle but a fixed weighted linear combination is adopted in projection with different-energy earlier, to obtain the projection image of organ-/ tissue composition, projection image with the organ-/ tissue of all projection angles makes up then, thereby produces one group of image that contains the fault plane structure of organ-/ tissue composition.
16. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 1, it is characterized in that: a projection image that sets the different angles of energy is synthesized in synthesizing earlier among the described step C, to obtain organizing the image of fault plane structure; Image with the formed fault plane of different-energy adopts weighting translation linear combination then, thereby obtains the image of organ-/ tissue composition fault plane structure.
17. a kind of method of utilizing multipotency X ray compound-projection numeral compound imaging according to claim 1, it is characterized in that: post processing comprises that the dynamic compression, the reduction of dynamic image noise, image-region selection, figure image intensifying, dynamic image of digital picture show among the described step D, obtains the image after a series of processing.
18. device that is used to realize described in claim 1, utilize the method for multipotency X ray compound-projection numeral compound imaging, it is characterized in that: comprise x-ray source and picture receiver, described picture receiver connects amplifier, analog-digital converter, digital projection picture pre-treating device, interim digital projection picture memorizer, Digital Image Processing and synthesizer, digital composograph preprocessor and digital composograph memorizer successively, and described digital composograph memorizer connects final image display or computer network output.
19. the device that utilizes multipotency X ray compound-projection numeral compound imaging according to claim 18, it is characterized in that: described x-ray source connects x-ray source high-frequency and high-voltage control circuit and x-ray source position control circuit, described picture receiver connects the receptor control circuit, and described x-ray source high-frequency and high-voltage control circuit, x-ray source position control circuit, receptor control circuit, Digital Image Processing and synthesizer, digital composograph preprocessor, digital composograph memorizer, final image display all connect terminal use's controller.
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103995010A (en) * 2014-01-26 2014-08-20 浙江康源医疗器械有限公司 Correction method for nonuniformity of spatial distribution of X-ray imaging
CN106562797A (en) * 2016-10-27 2017-04-19 南京航空航天大学 System and method for single-exposure digital subtraction angiography imaging
CN107753048A (en) * 2012-09-05 2018-03-06 三星电子株式会社 X-ray imaging device
CN110084753A (en) * 2019-05-29 2019-08-02 深圳市安健科技股份有限公司 Dynamic DR image split-joint method and terminal based on Multi-sensor Fusion
CN112730468A (en) * 2019-10-28 2021-04-30 同方威视技术股份有限公司 Article detection device and method for detecting article
CN112924478A (en) * 2021-01-29 2021-06-08 上海科技大学 Overhead cable detection system based on dual-energy digital X-ray imaging
WO2022053049A1 (en) * 2020-09-11 2022-03-17 上海联影医疗科技股份有限公司 Dynamic perspective method, apparatus and system for c-shaped arm equipment

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5490196A (en) * 1994-03-18 1996-02-06 Metorex International Oy Multi energy system for x-ray imaging applications
CN101175440A (en) * 2005-05-18 2008-05-07 株式会社日立医药 Radiograph and image processing program
CN101273896A (en) * 2007-03-30 2008-10-01 通用电气公司 Image acquisition and processing chain for dual-energy radiography using a portable flat panel detector

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5490196A (en) * 1994-03-18 1996-02-06 Metorex International Oy Multi energy system for x-ray imaging applications
CN101175440A (en) * 2005-05-18 2008-05-07 株式会社日立医药 Radiograph and image processing program
CN101273896A (en) * 2007-03-30 2008-10-01 通用电气公司 Image acquisition and processing chain for dual-energy radiography using a portable flat panel detector

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107753048A (en) * 2012-09-05 2018-03-06 三星电子株式会社 X-ray imaging device
CN107753048B (en) * 2012-09-05 2020-12-29 三星电子株式会社 X-ray imaging apparatus
CN103995010A (en) * 2014-01-26 2014-08-20 浙江康源医疗器械有限公司 Correction method for nonuniformity of spatial distribution of X-ray imaging
CN103995010B (en) * 2014-01-26 2016-03-23 浙江康源医疗器械有限公司 The bearing calibration of X-radial imaging space distribution unevenness
CN106562797A (en) * 2016-10-27 2017-04-19 南京航空航天大学 System and method for single-exposure digital subtraction angiography imaging
CN106562797B (en) * 2016-10-27 2021-01-01 南京航空航天大学 Single exposure digital subtraction angiography imaging system
CN110084753A (en) * 2019-05-29 2019-08-02 深圳市安健科技股份有限公司 Dynamic DR image split-joint method and terminal based on Multi-sensor Fusion
CN110084753B (en) * 2019-05-29 2023-04-11 深圳市安健科技股份有限公司 Dynamic DR image splicing method and terminal based on multi-sensor fusion
CN112730468A (en) * 2019-10-28 2021-04-30 同方威视技术股份有限公司 Article detection device and method for detecting article
WO2022053049A1 (en) * 2020-09-11 2022-03-17 上海联影医疗科技股份有限公司 Dynamic perspective method, apparatus and system for c-shaped arm equipment
CN112924478A (en) * 2021-01-29 2021-06-08 上海科技大学 Overhead cable detection system based on dual-energy digital X-ray imaging

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