CN102000129A - Medicinal composition with effect of improving immunity - Google Patents
Medicinal composition with effect of improving immunity Download PDFInfo
- Publication number
- CN102000129A CN102000129A CN201010545452XA CN201010545452A CN102000129A CN 102000129 A CN102000129 A CN 102000129A CN 201010545452X A CN201010545452X A CN 201010545452XA CN 201010545452 A CN201010545452 A CN 201010545452A CN 102000129 A CN102000129 A CN 102000129A
- Authority
- CN
- China
- Prior art keywords
- pharmaceutical composition
- weight portion
- preparation
- powder
- enhancing immunity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention belongs to the field of medicaments or healthcare foods and discloses a medicinal composition with the effect of improving immunity. The medicinal composition is characterized by comprising the following components in part by weight: 0.1 to 2 parts of cordyceps polysaccharide or 0.5 to 3 parts of fermented cordyceps bacterial powder, 0.5 to 5 parts of glossy ganoderma and 6 to 20 parts of American ginseng. Or the medicinal composition comprises the following components in part by weight: 0.1 to 2 parts of cordyceps polysaccharide or 0.5 to 3 parts of fermented cordyceps bacterial powder, 0.01 to 2 parts of glossy ganoderma polysaccharide and 0.05 to 2 parts of American ginseng total saponins. Pharmacological experiments show that the medicinal composition has very good effect of improving immunity.
Description
Technical field
The present invention relates to medicine or field of health care food, be specifically related to a kind of pharmaceutical composition with enhancing immunity effect
Background technology
Immunity is the defense mechanism of human body self, is human body identification and any foreign body (virus, antibacterial etc.) of eliminating external intrusion; Handle the ability of self cell and identification and the processing vivo mutations cell and the virus infected cell of old and feeble, damage, dead, degeneration.Modern immunology thinks that immunity is human body identification and the physiological reaction of getting rid of " dissident ".What carry out this function in the human body is immune system.Over millions of years, human at environment that not only is fit to existence but also is fraught with risks of life, the mankind are able to survival, have also obtained outstanding immunity.Immunity is the product of biological evolution process thus.
The health of hypoimmunity is easy to infected or cancer stricken; Immunity is extraordinary also can to produce insalubrious result, as causing anaphylaxis, autoimmune disease etc.A variety of causes makes immune system normally not bring into play protective effect, in the case, very easily cause infection such as antibacterial, virus, fungus, so the most direct performance of hypoimmunity is exactly liable to illness.Because of often ill, increased the weight of the consumption of body, thus generally have a delicate constitution, performances such as malnutrition, lethargy, fatigue and weak, appetite depression, sleep disorder, sick, have an injection and take medicine the normal potluck that just gets married.Each sickly all will could recover for a long time, and usually outbreak repeatedly.If things go on like this can cause health and intelligence development bad, also easily bring out major disease.Underlying causes is that hypoimmunity or immunity are unsound.When the immune function of human body imbalance, when perhaps immune system was unsound, following point will show effect repeatedly: so--show effect repeatedly repeatedly, asthma is shown effect repeatedly, bronchitis shows effect repeatedly, pneumonia is shown effect repeatedly, suffering from diarrhoea show effect-necessarily can't neglect repeatedly by outbreak, tonsillitis for flu.
Have huge harm based on hypoimmunity, therefore, strengthen the food or the medicine of body immunity, be medicine worker's in this year one of research hot fields always.
Summary of the invention
For these reasons, the applicant is the basis by clinical research for many years, is guidance with the modern Chinese medicine theory, with fermented Cordyceps powder or Cordyceps polysaccharide, adds Ganoderma and Radix Panacis Quinquefolii and carries out compatibility; Perhaps with fermented Cordyceps powder or Cordyceps polysaccharide, add ganoderan and American ginseng total saponins and carry out compatibility, obtain the new enhancing immunity pharmaceutical composition that has, pharmacological testing shows that the new pharmaceutical composition of the present invention has the effect of better enhancing immunity.
The present invention is achieved through the following technical solutions.
A kind of pharmaceutical composition with enhancing immunity effect is characterized in that pharmaceutical composition comprises Cordyceps polysaccharide 0.1-2 weight portion or fermented Cordyceps powder 0.5-3 weight portion, Ganoderma 0.5-5 weight portion, Radix Panacis Quinquefolii 6-20 weight portion; Perhaps pharmaceutical composition comprises Cordyceps polysaccharide 0.1-2 weight portion or fermented Cordyceps powder 0.5-3 weight portion, ganoderan 0.01-2 weight portion, American ginseng total saponins 0.05-2 weight portion.
Wherein said ganoderan is prepared according to prior art; Wherein American ginseng total saponins is prepared according to prior art.
Aforementioned pharmaceutical compositions also comprises Flos Rosae Rugosae, Flos Osmanthi Fragrantis, Mel, pollen, Radix Rhodiolae, the structure Qi, Fructus Jujubae,, lentinan, Grifola frondosa, Pandan Leaves, D-ribose, in the barley green one or more
Aforementioned pharmaceutical compositions also comprises rose candy, Sweet-scented Osmanthus, white sugar, sucrose, crystal sugar, chitosan, glucose, citric acid, malic acid, probiotic bacteria, oligofructose, walnut powder, Fructus Hordei Germinatus powder, maltose alcohol, xylitol, mannitol, essence, in the cyclodextrin one or more.
Aforementioned pharmaceutical compositions also comprises milk.
Cordyceps polysaccharide 0.1-2 weight portion or fermented Cordyceps powder 0.5-3 weight portion in the pharmaceutical composition, Ganoderma 0.5-5 weight portion, Radix Panacis Quinquefolii 6-20 weight portion also adds milk or milk powder and rose candy.
Cordyceps polysaccharide 0.1-2 weight portion or fermented Cordyceps powder 0.5-3 weight portion in the pharmaceutical composition, Ganoderma 0.5-5 weight portion, Radix Panacis Quinquefolii 6-20 weight portion also adds Mel and rose candy.
The pharmaceutical preparation or the food of aforementioned pharmaceutical compositions preparation.
The pharmaceutical preparation or the food of aforementioned pharmaceutical compositions preparation are tablet, granule, pill, oral liquid or capsule
The beverage of aforementioned pharmaceutical compositions preparation.
Aforementioned pharmaceutical compositions also comprises milk powder or the milk powder that adds milk produced.
Fermented Cordyceps powder of the present invention refer to from natural cordyceps separate and arbitrary strain fermentation and mycelium powder, can use its extract.
Cordyceps polysaccharide of the present invention can be to extract from the natural cs sporophore, or extracts from the artificial culture Cordyceps sporophore, or extracts from the Cordyceps mycelium of fermentation culture or fermentation liquid.
Ganoderan of the present invention can be to extract from the natural glossy ganoderma sporophore and get, also can be from the artificial ganoderma sporophore, to extract and get, or extraction and getting from artificial ganoderma yeast powder (fermentation liquid).
Milk powder of the present invention is can be for selling and edible milk powder on the market.The standard that meets State Administration for Quality Supervision and Inspection and Quarantine's promulgation: CCGF 114.2-2008.
Pharmacological testing
1, the enhancing immunity functional experiment 1
Trial drug:
Test 1 group: Cordyceps.
Test 2 groups: fermented Cordyceps powder 2g, Ganoderma 4g, American ginseng total saponins 3g.
Test 3 groups: Cordyceps polysaccharide 0.1g, Ganoderma 0.5g, Radix Panacis Quinquefolii 6g.
Test 4 groups: Cordyceps polysaccharide 2g, Ganoderma 5g, Radix Panacis Quinquefolii 20g.
Test 5 groups: Cordyceps polysaccharide 1g, Ganoderma 3g, Radix Panacis Quinquefolii 10g.
Test 6 groups: Cordyceps polysaccharide 1.2g, Ganoderma 3g, Radix Panacis Quinquefolii 16g, lentinan 3g.
Experimental animal: the female white mice of Kunming kind, body weight 18-22g.
Test method: get the mice random packet: blank group, trial drug group, mice gastric infusion every day 1 time, each dosage is 0.5g/kg, the blank group waits the distilled water of capacity.Respectively animal being carried out every immune indexes behind the 30d continuously measures.
Mice delayed allergy (DTH) is measured: in irritating stomach the 26th day, inject 2% sheep red blood cell (SRBC) (SRBC) 0.2ml/ to mouse peritoneal and only carry out sensitization, after immunity the 4th day the left back toe ring of the every Mus subcutaneous injection 20%SRBC of portion (20 μ l/ only) attack.And 24h measures the same position of the left back sufficient intestinal of every Mus thickness before attacking and after attacking, and calculates and attacks forward and backward difference, carries out variance analysis.Result of the test sees Table 1.
Table 1 pair mouse DTH measurement result (24h)
Annotate: compare * * P＜0.01, * P＜0.05 with matched group; Compare △ P＜0.05 for 1 group with test; Compare #P＜0.05 for 2 groups with test.
2, the enhancing immunity functional experiment 2
Trial drug:
Test 1 group: Cordyceps.
Test 2 groups: fermented Cordyceps powder 2g, Ganoderma 4g, American ginseng total saponins 3g.
Test 3 groups: fermented Cordyceps powder 0.5g, Ganoderma 0.5g, Radix Panacis Quinquefolii 6g.
Test 4 groups: fermented Cordyceps powder 3g, Ganoderma 5g, Radix Panacis Quinquefolii 20g.
Test 5 groups: fermented Cordyceps powder 2g, Ganoderma 3.5g, Radix Panacis Quinquefolii 12g.
Test 6 groups: fermented Cordyceps powder 1.5g, Ganoderma 2g, Radix Panacis Quinquefolii 9g, Fructus Lycii 4g.
Experimental animal: the female white mice of Kunming kind, body weight 18-22g.
Test method: get the mice random packet: blank group, trial drug group, mice gastric infusion every day 1 time, each dosage is 0.5g/kg, the blank group waits the distilled water of capacity.Respectively animal being carried out every immune indexes behind the 30d continuously measures.
ConA inducing mouse splenocyte transformation experiment (mtt assay): to the aseptic spleen of getting of each group mice, the system splenocyte suspension, adjusting splenocyte concentration with RPMI 1640 complete culture solutions is 3 * 10
9Individual/L, carry out lymphproliferation response according to MTr method in the program, survey its absorbance (A) at 752-C ultraviolet-uisible spectrophotometer 570nm wavelength place at last, calculate ConA
+With ConA
-The absorbance value difference in each hole.Carry out variance analysis.Result of the test sees Table 2.
Table 2 pair mouse spleen lymphocyte conversion test is measurement result (24h) as a result
Annotate: compare * P＜0.05 with matched group; Compare △ P＜0.05 for 1 group with test; Compare #P＜0.05 for 2 groups with test.
3, the enhancing immunity functional experiment 3
Trial drug:
Test 1 group: Cordyceps.
Test 2 groups: fermented Cordyceps powder 2g, Ganoderma 4g, American ginseng total saponins 3g.
Test 3 groups: Cordyceps polysaccharide 0.1g, ganoderan 0.01g, American ginseng total saponins 0.05g.
Test 4 groups: Cordyceps polysaccharide 2g, ganoderan 2g, American ginseng total saponins 2g.
Test 5 groups: Cordyceps polysaccharide 1g, ganoderan 0.5g, American ginseng total saponins 0.8g.
Test 6 groups: Cordyceps polysaccharide 1.2g, ganoderan 0.3g, American ginseng total saponins 0.4g, Flos Rosae Rugosae, Flos Osmanthi Fragrantis, Mel, pollen, each 1g of Radix Rhodiolae.
Experimental animal: the female white mice of Kunming kind, body weight 18-22g.
Test method: get the mice random packet: blank group, trial drug group, mice gastric infusion every day 1 time, each dosage is 0.1g/kg, the blank group waits the distilled water of capacity.Respectively animal being carried out every immune indexes behind the 30d continuously measures.
Serum hemolysin is measured: in irritating stomach the 25th day to mouse peritoneal injection 2%SRBC (0.2ml/ only), after immunity, plucked the eyeball blood sampling on the 5th day, separation of serum is also measured at the clear hemolysin of the enterprising promoting the circulation of blood of Microhemagglutination plate: hatch 3h for 37 ℃, statistics hemagglutination degree calculates the corresponding antibodies product.Carry out variance analysis.Result of the test sees Table 3.
Table 3 pair mice serum hemolysin measurement result
Annotate: compare * * P＜0.01, * P＜0.05 with matched group; Compare △ P＜0.05 for 1 group with test; Compare #P＜0.05 for 2 groups with test.
4, the enhancing immunity functional experiment 4
Trial drug:
Test 1 group: Cordyceps.
Test 2 groups: fermented Cordyceps powder 2g, Ganoderma 4g, American ginseng total saponins 3g.
Test 3 groups: fermented Cordyceps powder 0.5g, ganoderan 0.01g, American ginseng total saponins 0.05g.
Test 4 groups: fermented Cordyceps powder 3g, ganoderan 2g, American ginseng total saponins 2g.
Test 5 groups: fermented Cordyceps powder 2g, ganoderan 0.75g, American ginseng total saponins 1.45g.
Test 6 groups: fermented Cordyceps powder 1.5g, ganoderan 0.3g, American ginseng total saponins 0.9g, Fructus Lycii 2g, Fructus Jujubae 4g, Grifola frondosa 2g, Pandan Leaves 1g, D-ribose 0.5g.
Experimental animal: the female white mice of Kunming kind, body weight 18-22g.
Test method: get the mice random packet: blank group, trial drug group, mice gastric infusion every day 1 time, each dosage is 0.1g/kg, the blank group waits the distilled water of capacity.Respectively animal being carried out every immune indexes behind the 30d continuously measures.
Antibody-producting cell (PFc) detects: in to mouse peritoneal injection 2%SRBC0.2ml/ only irritating stomach the 25th day, putting to death in the 5th day after immunity, dissect and get spleen and prepare splenocyte suspension, is 5 * 10 with RPMI1640 complete culture solution adjustment splenocyte concentration
9Individual/L.The follow procedure method prepares the agarose slide, at CO
2Incubator (37 ℃, 5%CO
2) in add complement behind the incubation 1.5h, incubation 1.5h counts the hemolysis plaque number that forms on every thin agar layer slide again.Carry out variance analysis.Result of the test sees Table 4.
Table 4 pair mouse antibodies cellulation testing result
Annotate: compare * * P＜0.01, * P＜0.05 with matched group; Compare △ P＜0.05 for 1 group with test; Compare #P＜0.05 for 2 groups with test.
5, the enhancing immunity functional experiment 5
Trial drug:
Test 1 group: fermented Cordyceps powder 0.9g, ganoderan 0.8g, American ginseng total saponins 0.09g.
Test 2 groups: Cordyceps polysaccharide 1.8g, ganoderan 1.5g, American ginseng total saponins 0.8g, Radix Astragali 3g.
Test 3 groups: fermented Cordyceps powder 2.5g, ganoderan 0.4g, American ginseng total saponins 0.8g, pollen 0.5g, Radix Rhodiolae 3g.
Experimental animal: the female white mice of Kunming kind, body weight 18-22g.
Test method: get the mice random packet: blank group, trial drug group, mice gastric infusion every day 1 time, each dosage is 0.1g/kg, the blank group waits the distilled water of capacity.Respectively animal being carried out every immune indexes behind the 30d continuously measures.
Mice carbon is cleaned up experiment: in order to each group mouse tail vein injection india ink (4 times of dilutions) 0.1ml/10gbw.Every Mus all behind injection prepared Chinese ink 2min and 10min adjoin blood sampling 20 μ l in punctual respectively, and add the people rapidly in 2ml 0.1% sodium carbonate liquor and shake up, survey absorbance (A) with 752-C ultraviolet-uisible spectrophotometer 600nm wavelength place.Get Mouse Liver simultaneously, spleen is weighed, and by formula calculates phagocytic index (a).Carry out variance analysis.Result of the test sees Table 5.
Table 5 pair clearance in mice result of the test
Annotate: compare * P＜0.05, * * P＜0.05 with matched group; Compare #P＜0.05 for 4 groups with test.
6, the enhancing immunity functional experiment 6
Trial drug:
Test 1 group: Cordyceps polysaccharide 0.1g, ganoderan 0.05g, American ginseng total saponins 0.09g.
Test 2 groups: Cordyceps polysaccharide 1g, ganoderan 1g, American ginseng total saponins 1g.
Experimental animal: the female white mice of Kunming kind, body weight 18-22g.
Test method: get the mice random packet: blank group, trial drug group, mice gastric infusion every day 1 time, each dosage is 0.1g/kg, the blank group waits the distilled water of capacity.Respectively animal being carried out every immune indexes behind the 30d continuously measures.
Turnover of Mouse Peritoneal Macrophages is engulfed the chicken red blood cell experiment: respectively organize mouse peritoneal and only inject 20% chicken erythrocyte suspension 1ml/ after last is tried thing, 30min puts to death mice at interval, human physiology saline 2ml/ is only annotated in the abdominal cavity, get abdominal cavity washing liquid film-making behind the jolting min, 37 ℃ of incubation 30min, rinsing, fixing poststaining microscopy.Counting is engulfed red macrophage number of chicken and macrophage phagocytic chicken red blood cell number, carries out variance analysis with each dosage group phagocytic rate conversion value and phagocytic index.Result of the test sees Table 6.
Table 5 couple mouse macrophage phagocytosis test result
Annotate: compare * P＜0.05 with matched group.
Preparation embodiment
Embodiment 1
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises Cordyceps polysaccharide 0.1g, Ganoderma 0.5g, Radix Panacis Quinquefolii 6g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
Embodiment 2
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises Cordyceps polysaccharide 2g, Ganoderma 5g, Radix Panacis Quinquefolii 20g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
Embodiment 3
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises Cordyceps polysaccharide 0.5g, Ganoderma 3g, Radix Panacis Quinquefolii 14g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
Embodiment 4
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises fermented Cordyceps powder 0.5g, Ganoderma 0.5g, Radix Panacis Quinquefolii 6g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
Embodiment 5
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises fermented Cordyceps powder 3g, Ganoderma 5g, Radix Panacis Quinquefolii 20g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
Embodiment 6
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises fermented Cordyceps powder 2g, Ganoderma 3g, Radix Panacis Quinquefolii 9g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
Embodiment 7
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises Cordyceps polysaccharide 0.1g, ganoderan 0.01g, American ginseng total saponins 0.05g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
Embodiment 8
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises Cordyceps polysaccharide 2g, ganoderan 2g, American ginseng total saponins 2g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
Embodiment 9
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises Cordyceps polysaccharide 0.95g, ganoderan 0.15g, American ginseng total saponins 0.40g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
Embodiment 10
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises fermented Cordyceps powder 0.5g, ganoderan 0.01g, American ginseng total saponins 0.05g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
Embodiment 11
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises fermented Cordyceps powder 3g, ganoderan 2g, American ginseng total saponins 2g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
Embodiment 12
A kind of pharmaceutical composition with enhancing immunity effect, pharmaceutical composition comprises fermented Cordyceps powder 0.6g, ganoderan 0.09g, American ginseng total saponins 0.55g.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Pharmaceutical composition also comprises adding milk.
Pharmaceutical composition also comprises milk powder or the milk powder that adds milk produced.
The foregoing description pharmaceutical composition also comprises Flos Rosae Rugosae, Flos Osmanthi Fragrantis, Mel, pollen, Radix Rhodiolae, the structure Qi, Fructus Jujubae, lentinan, Grifola frondosa, Pandan Leaves, in the D-ribose one or more
The foregoing description Chinese medicine compositions also comprises rose candy, Sweet-scented Osmanthus, white sugar, sucrose, crystal sugar, chitosan, glucose, citric acid, malic acid, probiotic bacteria, oligofructose, barley green, walnut powder, Fructus Hordei Germinatus powder, maltose alcohol, xylitol, mannitol, essence, in the cyclodextrin one or more.
Embodiment 13
A kind of pharmaceutical composition with enhancing immunity effect, Cordyceps polysaccharide 0.1g wherein, Ganoderma 0.5g, Radix Panacis Quinquefolii 6g, it is an amount of also to add milk or milk powder and rose candy.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
The milk powder of preparation of pharmaceutical compositions or milk powder
Embodiment 14
A kind of pharmaceutical composition with enhancing immunity effect, Cordyceps polysaccharide 2g wherein, Ganoderma 5g, Radix Panacis Quinquefolii 20g, it is an amount of also to add milk or milk powder and rose candy.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
The milk powder of preparation of pharmaceutical compositions or milk powder
Embodiment 15
A kind of pharmaceutical composition with enhancing immunity effect, Cordyceps polysaccharide 0.9g wherein, Ganoderma 2.5g, Radix Panacis Quinquefolii 14g, it is an amount of also to add milk or milk powder and rose candy.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
The milk powder of preparation of pharmaceutical compositions or milk powder
Embodiment 16
A kind of pharmaceutical composition with enhancing immunity effect, fermented Cordyceps powder 0.5g wherein, Ganoderma 0.5g, Radix Panacis Quinquefolii 6g, it is an amount of also to add milk or milk powder and rose candy.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
The milk powder of preparation of pharmaceutical compositions or milk powder
Embodiment 17
A kind of pharmaceutical composition with enhancing immunity effect, fermented Cordyceps powder 3g wherein, Ganoderma 5g, Radix Panacis Quinquefolii 20g, it is an amount of also to add milk or milk powder and rose candy.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
The milk powder of preparation of pharmaceutical compositions or milk powder
Embodiment 18
A kind of pharmaceutical composition with enhancing immunity effect, fermented Cordyceps powder 2g wherein, Ganoderma 1.5g, Radix Panacis Quinquefolii 8g, it is an amount of also to add milk or milk powder and rose candy.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
The milk powder of preparation of pharmaceutical compositions or milk powder
Embodiment 19
A kind of pharmaceutical composition with enhancing immunity effect, Cordyceps polysaccharide 0.1g wherein, Ganoderma 0.5g, Radix Panacis Quinquefolii 6g also adds Mel and rose candy is an amount of.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Embodiment 20
A kind of pharmaceutical composition with enhancing immunity effect, Cordyceps polysaccharide 2g wherein, Ganoderma 5g, Radix Panacis Quinquefolii 20g also adds Mel and rose candy is an amount of.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Embodiment 21
A kind of pharmaceutical composition with enhancing immunity effect, Cordyceps polysaccharide 0.8g wherein, Ganoderma 4.5g, Radix Panacis Quinquefolii 8g also adds Mel and rose candy is an amount of.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Embodiment 22
A kind of pharmaceutical composition with enhancing immunity effect, fermented Cordyceps powder 0.5g wherein, Ganoderma 0.5g, Radix Panacis Quinquefolii 6g also adds Mel and rose candy is an amount of.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Embodiment 23
A kind of pharmaceutical composition with enhancing immunity effect, fermented Cordyceps powder 3g wherein, Ganoderma 5g, Radix Panacis Quinquefolii 20g also adds Mel and rose candy is an amount of.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Embodiment 24
A kind of pharmaceutical composition with enhancing immunity effect, fermented Cordyceps powder 1.4g wherein, Ganoderma 1.5g, Radix Panacis Quinquefolii 12g also adds Mel and rose candy is an amount of.
The pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
The beverage of preparation of pharmaceutical compositions.
Milk powder of the present invention is can be for selling and edible milk powder on the market.The standard that meets State Administration for Quality Supervision and Inspection and Quarantine's promulgation: CCGF 114.2-2008.
Claims (9)
1. the pharmaceutical composition with enhancing immunity effect is characterized in that pharmaceutical composition comprises Cordyceps polysaccharide 0.1-2 weight portion or fermented Cordyceps powder 0.5-3 weight portion, Ganoderma 0.5-5 weight portion, Radix Panacis Quinquefolii 6-20 weight portion; Perhaps pharmaceutical composition comprises Cordyceps polysaccharide 0.1-2 weight portion or fermented Cordyceps powder 0.5-3 weight portion, ganoderan 0.01-2 weight portion, American ginseng total saponins 0.05-2 weight portion.
2. a kind of pharmaceutical composition according to claim 1 with enhancing immunity effect, wherein pharmaceutical composition also comprises Flos Rosae Rugosae, Flos Osmanthi Fragrantis, Mel, pollen, Radix Rhodiolae, Fructus Lycii, Fructus Jujubae, lentinan, Grifola frondosa, Pandan Leaves, D-ribose, in the barley green one or more
3. a kind of pharmaceutical composition according to claim 1 with enhancing immunity effect, wherein pharmaceutical composition also comprises rose candy, Sweet-scented Osmanthus, white sugar, sucrose, crystal sugar, chitosan, glucose, citric acid, malic acid, probiotic bacteria, oligofructose, walnut powder, Fructus Hordei Germinatus powder, maltose alcohol, xylitol, mannitol, essence, in the cyclodextrin one or more.
4. a kind of pharmaceutical composition according to claim 1 with enhancing immunity effect, wherein Cordyceps polysaccharide 0.1-2 weight portion or fermented Cordyceps powder 0.5-3 weight portion, Ganoderma 0.5-5 weight portion, Radix Panacis Quinquefolii 6-20 weight portion also adds milk or milk powder and rose candy.
5. a kind of pharmaceutical composition according to claim 1 with enhancing immunity effect, wherein Cordyceps polysaccharide 0.1-2 weight portion or fermented Cordyceps powder 0.5-3 weight portion, Ganoderma 0.5-5 weight portion, Radix Panacis Quinquefolii 6-20 weight portion also adds Mel and rose candy.
6. according to claim 1-5 each described a kind of pharmaceutical composition, the wherein pharmaceutical preparation of preparation of pharmaceutical compositions or food with enhancing immunity effect.
7. according to each described a kind of pharmaceutical composition with enhancing immunity effect of claim 1-5, wherein the pharmaceutical preparation of preparation of pharmaceutical compositions or food are tablet, granule, pill, oral liquid or capsule.
8. according to claim 1-5 each described a kind of pharmaceutical composition, wherein beverage of preparation of pharmaceutical compositions with enhancing immunity effect.
9. a kind of pharmaceutical composition with enhancing immunity effect according to claim 4, wherein preparation of pharmaceutical compositions becomes milk powder or milk powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010545452XA CN102000129A (en) | 2010-11-16 | 2010-11-16 | Medicinal composition with effect of improving immunity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010545452XA CN102000129A (en) | 2010-11-16 | 2010-11-16 | Medicinal composition with effect of improving immunity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102000129A true CN102000129A (en) | 2011-04-06 |
Family
ID=43807997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201010545452XA Pending CN102000129A (en) | 2010-11-16 | 2010-11-16 | Medicinal composition with effect of improving immunity |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102000129A (en) |
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188467A (en) * | 2011-05-10 | 2011-09-21 | 北京采瑞医药科技有限公司 | Traditional Chinese medicine composition for reinforcing vital energy and consolidating constitution, boosting human immunity, resisting fatigue and tumor, and delaying aging |
| CN102266054A (en) * | 2011-07-26 | 2011-12-07 | 西藏月王生物技术有限公司 | Aweto ferment and preparation method thereof |
| CN102551058A (en) * | 2012-01-17 | 2012-07-11 | 北京东方红航天生物技术股份有限公司 | Chinese medicinal health-care product with function of enhancing immunity |
| CN102742690A (en) * | 2012-07-19 | 2012-10-24 | 瑞福祥药业（广西）有限公司 | Health-care functional tea and preparation method thereof |
| CN102885301A (en) * | 2012-09-19 | 2013-01-23 | 北京同仁堂健康药业股份有限公司 | Composition for enhancing immunity and preparation method thereof |
| WO2013177947A1 (en) * | 2012-05-29 | 2013-12-05 | 江中药业股份有限公司 | Composition and use thereof for preventing and treating hepatitis b |
| WO2013177948A1 (en) | 2012-05-29 | 2013-12-05 | 江中药业股份有限公司 | Application of composition in preparing health care product or medicine for preventing and treating leukopenia caused by radiotherapy and chemotherapy |
| WO2013177944A1 (en) | 2012-05-29 | 2013-12-05 | 江中药业股份有限公司 | Use of composition in preparing health care products or medicines for preventing and treating allergic diseases |
| CN103445046A (en) * | 2012-05-30 | 2013-12-18 | 孔翔 | Food composition for improving immunity and preparation method thereof |
| CN103462016A (en) * | 2013-09-11 | 2013-12-25 | 大连海晏堂生物有限公司 | Ginseng lozenge and preparation method thereof |
| CN104366485A (en) * | 2014-12-06 | 2015-02-25 | 黑龙江众生生物工程有限公司 | Immunity enhancing tablet and method for manufacturing same |
| CN104905262A (en) * | 2015-05-29 | 2015-09-16 | 湖北省农业科学院农产品加工与核农技术研究所 | Method for preparing cordyceps sinensis and lucid ganoderma compound preparation |
| CN105248801A (en) * | 2015-09-02 | 2016-01-20 | 庆元大山合菌物科技有限公司 | Grifola frondosus hard candy and preparation method thereof |
| CN105920303A (en) * | 2016-06-01 | 2016-09-07 | 朱国平 | Medicinal compound for improving immunity of human body as well as preparation method and application of medicinal compound |
| CN106036307A (en) * | 2016-05-10 | 2016-10-26 | 香格里拉东旺生物科技有限公司 | A cordyceps militaris polysaccharide compound drink and a preparing method thereof |
| CN106722954A (en) * | 2016-12-21 | 2017-05-31 | 安徽新华学院 | It is a kind of to strengthen food of body immunity and preparation method thereof |
| CN108244432A (en) * | 2018-01-24 | 2018-07-06 | 江苏阜丰生物科技有限公司 | A kind of fermentation Cordyceps militaris probiotic beverage and preparation method thereof |
| JP2019198245A (en) * | 2018-05-14 | 2019-11-21 | 株式会社ノエビア | Beverage and production method of the same |
| CN116763812A (en) * | 2023-08-17 | 2023-09-19 | 青岛农业大学 | American ginseng polysaccharide, osteoporosis treatment medicine prepared from American ginseng polysaccharide and application of American ginseng polysaccharide |
-
2010
- 2010-11-16 CN CN201010545452XA patent/CN102000129A/en active Pending
Cited By (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188467A (en) * | 2011-05-10 | 2011-09-21 | 北京采瑞医药科技有限公司 | Traditional Chinese medicine composition for reinforcing vital energy and consolidating constitution, boosting human immunity, resisting fatigue and tumor, and delaying aging |
| CN102188467B (en) * | 2011-05-10 | 2012-12-12 | 北京采瑞医药科技有限公司 | Traditional Chinese medicine composition for reinforcing vital energy and consolidating constitution, boosting human immunity, resisting fatigue and tumor, and delaying aging |
| CN102266054A (en) * | 2011-07-26 | 2011-12-07 | 西藏月王生物技术有限公司 | Aweto ferment and preparation method thereof |
| CN102266054B (en) * | 2011-07-26 | 2013-01-30 | 西藏月王生物技术有限公司 | Fermentation functionality aweto beverage and preparation method thereof |
| CN102551058A (en) * | 2012-01-17 | 2012-07-11 | 北京东方红航天生物技术股份有限公司 | Chinese medicinal health-care product with function of enhancing immunity |
| EP2857030B1 (en) * | 2012-05-29 | 2018-10-10 | Jiangzhong Pharmaceutical Co., Ltd. | Composition for use in preventing and treating allergic diseases |
| US10086030B2 (en) | 2012-05-29 | 2018-10-02 | Jiangzhong Pharmaceutical Co., Ltd. | Use of composition in preparing health care products or medicines for preventing and treating allergic diseases |
| US9744203B2 (en) | 2012-05-29 | 2017-08-29 | Jiangzhong Pharmaceutical Co., Ltd. | Application of composition in preparing health care product or medicine for preventing and treating leukopenia caused by radiotherapy and chemotherapy |
| WO2013177947A1 (en) * | 2012-05-29 | 2013-12-05 | 江中药业股份有限公司 | Composition and use thereof for preventing and treating hepatitis b |
| WO2013177948A1 (en) | 2012-05-29 | 2013-12-05 | 江中药业股份有限公司 | Application of composition in preparing health care product or medicine for preventing and treating leukopenia caused by radiotherapy and chemotherapy |
| WO2013177944A1 (en) | 2012-05-29 | 2013-12-05 | 江中药业股份有限公司 | Use of composition in preparing health care products or medicines for preventing and treating allergic diseases |
| CN103445046A (en) * | 2012-05-30 | 2013-12-18 | 孔翔 | Food composition for improving immunity and preparation method thereof |
| CN102742690B (en) * | 2012-07-19 | 2013-08-14 | 瑞福祥药业（广西）有限公司 | Health-care functional tea and preparation method thereof |
| CN102742690A (en) * | 2012-07-19 | 2012-10-24 | 瑞福祥药业（广西）有限公司 | Health-care functional tea and preparation method thereof |
| CN102885301B (en) * | 2012-09-19 | 2013-12-11 | 北京同仁堂健康药业股份有限公司 | Composition for enhancing immunity and preparation method thereof |
| CN102885301A (en) * | 2012-09-19 | 2013-01-23 | 北京同仁堂健康药业股份有限公司 | Composition for enhancing immunity and preparation method thereof |
| CN103462016A (en) * | 2013-09-11 | 2013-12-25 | 大连海晏堂生物有限公司 | Ginseng lozenge and preparation method thereof |
| CN104366485A (en) * | 2014-12-06 | 2015-02-25 | 黑龙江众生生物工程有限公司 | Immunity enhancing tablet and method for manufacturing same |
| CN104905262A (en) * | 2015-05-29 | 2015-09-16 | 湖北省农业科学院农产品加工与核农技术研究所 | Method for preparing cordyceps sinensis and lucid ganoderma compound preparation |
| CN105248801A (en) * | 2015-09-02 | 2016-01-20 | 庆元大山合菌物科技有限公司 | Grifola frondosus hard candy and preparation method thereof |
| CN106036307A (en) * | 2016-05-10 | 2016-10-26 | 香格里拉东旺生物科技有限公司 | A cordyceps militaris polysaccharide compound drink and a preparing method thereof |
| CN105920303A (en) * | 2016-06-01 | 2016-09-07 | 朱国平 | Medicinal compound for improving immunity of human body as well as preparation method and application of medicinal compound |
| CN106722954A (en) * | 2016-12-21 | 2017-05-31 | 安徽新华学院 | It is a kind of to strengthen food of body immunity and preparation method thereof |
| CN108244432A (en) * | 2018-01-24 | 2018-07-06 | 江苏阜丰生物科技有限公司 | A kind of fermentation Cordyceps militaris probiotic beverage and preparation method thereof |
| JP2019198245A (en) * | 2018-05-14 | 2019-11-21 | 株式会社ノエビア | Beverage and production method of the same |
| CN116763812A (en) * | 2023-08-17 | 2023-09-19 | 青岛农业大学 | American ginseng polysaccharide, osteoporosis treatment medicine prepared from American ginseng polysaccharide and application of American ginseng polysaccharide |
| CN116763812B (en) * | 2023-08-17 | 2023-11-03 | 青岛农业大学 | American ginseng polysaccharide, osteoporosis treatment medicine prepared from American ginseng polysaccharide and application of American ginseng polysaccharide |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102000129A (en) | Medicinal composition with effect of improving immunity | |
| CN102166227B (en) | Pharmaceutical composition with function of enhancing immunity | |
| CN102133241B (en) | Medicine composite with effect of improving immunity | |
| CN102133250B (en) | Medicinal composition with effect of improving immunity | |
| CN105816430B (en) | A kind of preparation method with antitumor action radix tetrastigme polyoses grain | |
| CN101716256B (en) | Preparation used for strengthening immunity | |
| CN107647405A (en) | A kind of pulvis with strengthen immunity function and preparation method thereof | |
| CN107668705A (en) | A kind of pulvis with strengthen immunity function and preparation method thereof | |
| CN102000122B (en) | Pharmaceutical composition with effect of improving immunity | |
| CN106727738A (en) | A kind of Phellinus glossy ganoderma powder and preparation method thereof | |
| CN108902628A (en) | A kind of anti-inflammatory probiotics solid beverage of children | |
| CN101856370A (en) | Medicine combination capable of regulating immunity | |
| CN107912771A (en) | A kind of stem of noble dendrobium composition with enhancing immune function and preparation method thereof | |
| CN101890056A (en) | Medicinal composition for enhancing immunologic function | |
| CN102058648A (en) | Medicinal composition for improving immunity | |
| CN101904874A (en) | Medicinal composition having effect of enhancing immunologic functions | |
| CN108813610A (en) | A kind of saussurea involucrata composition and its application for improving immunity | |
| CN103330211A (en) | Composition with immunoregulation function and preparation method and application of composition | |
| CN106377541A (en) | Polysaccharide composition and application thereof | |
| CN101862354A (en) | Pharmaceutical composition for adjusting immunity | |
| CN104286844A (en) | Food, health product or medicine composition capable of improving immunity | |
| CN107951992A (en) | A kind of Chinese medicine composition for strengthen immunity and preparation method thereof | |
| CN107223966A (en) | It is a kind of to be used to improve sweet oral liquid of Rong's grass of immunity and preparation method thereof | |
| CN102406172B (en) | Health-care food for enhancing immunity and preparation method thereof | |
| CN103082286B (en) | Health-care food for enhancing immunity and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110406 |