CN101803925A - Monitoring device of blood oxygen saturation in motion state - Google Patents
Monitoring device of blood oxygen saturation in motion state Download PDFInfo
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- CN101803925A CN101803925A CN 201010136449 CN201010136449A CN101803925A CN 101803925 A CN101803925 A CN 101803925A CN 201010136449 CN201010136449 CN 201010136449 CN 201010136449 A CN201010136449 A CN 201010136449A CN 101803925 A CN101803925 A CN 101803925A
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title claims abstract description 58
- 229910052760 oxygen Inorganic materials 0.000 title claims abstract description 58
- 239000001301 oxygen Substances 0.000 title claims abstract description 58
- 210000004369 blood Anatomy 0.000 title claims abstract description 55
- 239000008280 blood Substances 0.000 title claims abstract description 55
- 238000012806 monitoring device Methods 0.000 title claims abstract description 14
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- 230000003321 amplification Effects 0.000 claims abstract description 17
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- 230000005622 photoelectricity Effects 0.000 claims description 11
- 210000005056 cell body Anatomy 0.000 claims description 4
- 238000012544 monitoring process Methods 0.000 abstract description 18
- 238000000034 method Methods 0.000 abstract description 9
- 238000006243 chemical reaction Methods 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 6
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010064719 Oxyhemoglobins Proteins 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 208000035861 hematochezia Diseases 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 230000009897 systematic effect Effects 0.000 description 2
- 238000006424 Flood reaction Methods 0.000 description 1
- 235000013405 beer Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
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- 238000013500 data storage Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
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- 230000005021 gait Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000002496 oximetry Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
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- 238000013186 photoplethysmography Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000010349 pulsation Effects 0.000 description 1
- 238000011946 reduction process Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
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- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention relates to a monitoring device of blood oxygen saturation in motion state in the technical field of medical appliances, which comprises a PPG signal generation module, a motion signal generation module, a signal processing module, a communication module and a man-machine interaction module. Compared with a traditional blood oxygen saturation monitoring device, the device adds the motion signal generation module for monitoring the motion acceleration of a space: in a signal acquisition stage, the output information of the motion signal generation module is used for adjusting the amplification process of the PPG signal; and in a signal processing stage, the output information of the motion signal generation module is used for eliminating the motion noise in the PPG signal. The monitoring device of blood oxygen saturation in motion state can effectively eliminate the impact of the motion noise in the blood oxygen monitoring process, improve the monitoring accuracy, and enlarge the scope of use of the device.
Description
Technical field
What the present invention relates to is a kind of device of Medical Instruments technical field, specifically is blood oxygen saturation monitoring device based under a kind of kinestate.
Background technology
The needed oxygen of human body metabolism, be by with blood in hemoglobin (Hb) be combined into to be transported in the different tissues cell behind the HbO2 Oxyhemoglobin (HbO2) and go.Blood oxygen saturation (SaO2) has then represented to be accounted for by the bonded HbO2 Oxyhemoglobin of oxygen (HbO2) in the blood percentage ratio of whole combinative hemoglobin (Hb), the i.e. concentration of blood oxygen in the blood.Therefore monitor SaO2 to understanding respiratory system, blood circulation situation and prevention histanoxia etc. plays an important role.
At present, existing oxygen saturation monitor device all is according to Lambert-beer principle and photoelectric technology, at first obtain photoelectricity volume pulsation wave (photoplethysmography under HONGGUANG and the infrared light by photoelectric technology, PPG), relatively calculate two PPG signals based on Lambert beer principle afterwards and obtain oximetry value.This device technique is ripe, in operation, is widely used in the clinical monitoring.Yet these monitorings all need experimenter's state of keeping quite, and motion is the main reason that influences signal monitoring.
Find that through existing technology retrieval Chinese application number is: 200510121269.6, name is called: can eliminate the blood oxygen measuring method and the device thereof of motion artifacts, this technology provides the blood oxygen measuring device that can realize eliminating motion artifacts.This device comprises: blood oxygen probe head component, and signal processing and amplifying assembly, the A/D conversion, the single-chip data processing components, Logic control module and power circuit, wherein probe assembly comprises: HONGGUANG, infrared light supply, drive circuit and light-receiving tube; Signal processing and amplifying assembly comprises: differential amplifier circuit and signal processing circuit; Logic control and functional module comprise: security function and communication function, single-chip data processing module assembly has comprised the motion artifacts module, the motion artifacts module comprises: pulse wave calculation of parameter, differential processing module, medium filtering module and area integral recurrence module.The outfan of this fortune merit interference module connects A/D conversion and logic control and functional module respectively.But this technology does not comprise the device of monitoring experimenter kinestate, relies on a large amount of calculating to remove the motion noise under the situation of not knowing experimenter's actual motion signal, and therefore the operand of device is excessive, and only effective to the tangible signal of Partial Feature.
Summary of the invention
The objective of the invention is to overcome the above-mentioned deficiency of prior art, blood oxygen saturation monitoring device based under a kind of kinestate is provided.The present invention is based on the motion monitoring signal of sensor and eliminate the motion noise, realize kinestate blood oxygen saturation monitoring down, it is accurate and volume is little, the advantage of light weight to have a monitoring.
The present invention is achieved by the following technical solutions:
The present invention includes: PPG signal generation module, motor message generation module, signal processing module, communication module and human-computer interaction module, wherein: the PPG signal generation module PPG signal under transmission HONGGUANG and the infrared light that links to each other with signal processing module, the motor message generation module acceleration magnitude of transmission people soma on three mutually perpendicular directions in space that link to each other with signal processing module, communication module link to each other with signal processing module transmission blood oxygen signal and heart rate information, human-computer interaction module link to each other with signal processing module transmission of control signals and display result information.
Described PPG signal generation module comprises: an infrared diode, a near infrared diode and a photodiode, wherein: infrared diode and near infrared diode reverse parallel connection, infrared diode all links to each other with signal processing module with near infrared diode, and photodiode links to each other with signal processing module.
Described motor message generation module is an acceleration transducer.
Described signal processing module comprises: microprocessor, the photoelectricity drive circuit, the amplification filtering circuit, power circuit and memory device, wherein: the photoelectricity drive circuit links to each other with PPG signal generation module and transmits the luminous current signal of control, the photoelectricity drive circuit links to each other with microprocessor to transmit and drives signal, the amplification filtering circuit links to each other with PPG signal generation module and transmits the PPG signal, microprocessor links to each other with the amplification filtering circuit and transmits the amplification filtering signal, microprocessor links to each other with the motor message generation module and transmits the acceleration signal of three directions, microprocessor links to each other with memory device and transmits blood oxygen signal and heart rate information, microprocessor links to each other with power circuit and transmits power information, microprocessor link to each other with communication module transmission blood oxygen signal and heart rate information, microprocessor link to each other with human-computer interaction module transmission of control signals and display result information.
Described microprocessor is provided with analog-digital converter.
Described communication module comprises: wire communication submodule and radio communication submodule, wherein: the wire communication submodule all links to each other with signal processing module with the radio communication submodule and transmits blood oxygen and heart rate information.
Described wire communication submodule comprises: photoelectric isolating device and RS232 serial ports, and wherein: photoelectric isolating device links to each other with signal processing module and transmits blood oxygen and heart rate information, and photoelectric isolating device links to each other with the RS232 serial ports and transmits blood oxygen and heart rate information.
Described radio communication submodule is based on the less radio-frequency transmitter module of ZIGBEE agreement, its link to each other with signal processing module wireless transmission blood oxygen and heart rate signal.
Described human-computer interaction module comprises: button and lattice lcd, and wherein: button links to each other with signal processing module and transmits control information, and lattice lcd links to each other with signal processing module and shows blood oxygen and heart rate result.
Work process of the present invention is: the conducting of microprocessor control photoelectricity drive circuit generates anti-phase amplified current; Two light emitting diodes are alternately luminous under the effect of negative-phase sequence curent; Photodiode receives the light of penetrate tissue, gives filter amplification circuit with current delivery; Filter amplification circuit is passed to microcontroller with pretreated PPG analogue signal; Microprocessor receives the PPG analogue signal and is converted into digital signal, carries out the PPG Digital Signal Processing; Microprocessor receives the acceleration signal of motor message generation module, and carries out acceleration signal and handle; Microprocessor recovers the PPG signal that the passive movement noise floods based on acceleration signal, and calculates blood oxygen and heart rate result; Microprocessor sends to wire communication module with result, and sends to host computer by the RS232 serial ports; Microprocessor sends to result wireless communication module and then is transferred to other receiving system; Microprocessor sends to display module with the result, shows real-time blood oxygen and heart rate by lattice lcd.Button links to each other with microprocessor for user selective system mode of operation.
Compared with prior art, the invention has the beneficial effects as follows: can effectively suppress the motion noise, realize that the blood oxygen signal under the non-peculair motion state monitors in real time: utilize acceleration sensor chip to generate motor message, quantized unknown originally motion noise, thereby effectively control the collection of PPG analogue signal and the noise reduction process of PPG digital signal, thereby realize kinestate hematochezia oxygen information monitoring; In addition, the wireless transmission that the present invention is based on the ZIGBEE agreement can realize monitoring blood oxygen, the high speed of heart rate information, the transmitted in both directions of low-power consumption.Therefore the present invention not only can improve the accuracy of oxygen saturation monitor, is equally applicable to the monitoring of kinestate hematochezia oxygen signal, enlarges the scope of application of such device, but also it is little to have a volume, and characteristics such as light weight have realized the conversion of real-time dynamic monitoring blood oxygen.
Description of drawings
Fig. 1 is a composition sketch map of the present invention.
The specific embodiment
Below embodiments of the invention are elaborated, present embodiment is being to implement under the prerequisite with the technical solution of the present invention, provided detailed embodiment and concrete operating process, but protection scope of the present invention is not limited to following embodiment.
Embodiment
As shown in Figure 1, present embodiment comprises: PPG signal generation module, the motor message generation module, signal processing module, communication module and human-computer interaction module, wherein: the PPG signal generation module PPG signal under transmission HONGGUANG and the infrared light that links to each other with signal processing module, the motor message generation module is by the SPI mouth acceleration magnitude of transmission people soma on three mutually perpendicular directions in space that link to each other with signal processing module, communication module links to each other with signal processing module and transmits blood oxygen information and heart rate information, and human-computer interaction module links to each other with signal processing module and transmits control information and monitoring result.
Described PPG signal generation module comprises: 840mn light emitting diode, 960mn light emitting diode and photodiode, wherein: 840mn light emitting diode and 960mn light emitting diode reverse parallel connection, the 840mn light emitting diode links to each other with signal processing module, the 960mn light emitting diode links to each other with signal processing module, 840mn light emitting diode and 960mn light emitting diode are alternately luminous, and photodiode links to each other with signal processing module and transmits the current signal that comprises blood oxygen information.
Described motor message generation module is an acceleration transducer, and the model of the acceleration transducer that present embodiment adopts is MMA7260QT, its transmission X that links to each other with signal processing module, Y, three axial acceleration of motion information of Z.
Described signal processing module comprises: microprocessor, the photoelectricity drive circuit, the amplification filtering circuit, power circuit and storage card, wherein: the photoelectricity drive circuit links to each other with PPG signal generation module and transmits the luminous current signal of control, the photoelectricity drive circuit links to each other with microprocessor, the amplification filtering circuit links to each other with PPG signal generation module and transmits the PPG signal, microprocessor links to each other with the amplification filtering circuit, microprocessor links to each other with the motor message generation module and transmits the acceleration signal of three directions, microprocessor links to each other with storage card and transmits blood oxygen signal and heart rate information, microprocessor links to each other with power circuit and transmits power information, microprocessor link to each other with communication module transmission blood oxygen signal and heart rate information, microprocessor link to each other with human-computer interaction module transmission of control signals and display result information.
Microprocessor described in the present embodiment is the super low-power consumption microprocessor MSP430FG439 of American TI Company, it is built-in with analog-digital converter, this chip is little except volume, outside low in energy consumption, chip contains abundant external resource, present embodiment uses two operational amplifier 0A wherein, 12 analog digital conversion ADC, two intervalometer TIMER etc.Not only simplify circuit design based on resource in the sheet of this microprocessor, dwindle the circuit volume, and avoid external electromagnetic interference, improve systematic function.
Described communication module comprises: wire communication submodule and radio communication submodule, wherein: the wire communication submodule all links to each other with signal processing module with the radio communication submodule and transmits blood oxygen and heart rate information.
Described wire communication submodule comprises: photoelectric isolating device and RS232 serial ports, and wherein: photoelectric isolating device links to each other with signal processing module and transmits blood oxygen and heart rate information, and photoelectric isolating device links to each other with the RS232 serial ports and transmits blood oxygen and heart rate information.
Described radio communication submodule is based on the less radio-frequency transmitter module of ZIGBEE agreement, its link to each other with signal processing module wireless transmission blood oxygen and heart rate signal, and present embodiment is selected the low-power consumption chip CC2500 of American TI Company for use.
Described human-computer interaction module comprises: the lattice lcd of button and 128*64, and wherein: button links to each other with signal processing module and transmits control information, and lattice lcd links to each other with signal processing module and shows blood oxygen and heart rate result.
The work process of present embodiment is:
1, startup self-detection: after system powers on, finish the initialization to microprocessor automatically, system's operate as normal is guaranteed in the initialization of acceleration chip, and the inspection of other module operate as normal.
2, the generation of PPG signal: under the control of microprocessor, PPG signal generation module generates the PPG signal, and the motor message generation module generates the acceleration magnitude of transmission people soma on three mutually perpendicular directions in space.
3, the amplification filtering of PPG signal: under moving situation, the situations such as seriously overflowing range to such an extent as to useful signal may be flooded by excessive motor message or drift about, present embodiment is corrected primary signal with the motor message of monitoring and is amplified, the PPG signal is effectively amplified, motor message is suppressed, and the signal after the amplification is removed other frequency content through filtering.
4, the analog digital conversion of PPG signal:, be that digital signal is used for follow-up Digital Signal Processing with analog signal conversion by the built-in analog-digital converter of microprocessor.
5, burbling noise: the PPG signal is amplifying through overcorrection, still contain the eclipsed noise signal of part time-domain frequency-domain characteristic after the filtering, present embodiment is further isolated noise by the method for adaptive-filtering based on PPG and acceleration signal, obtains ideal PPG signal.
6, data storage: system is saved to the PPG signal on the built-in storage card.
7, physiological parameter shows and transmission: based on acceleration and PPG signal, system can obtain the gait about monitoring person, and parameters such as heart rate and blood oxygen saturation show monitoring result by lattice lcd, and transmit by communication module.
The advantage of present embodiment is: the MMA7260QT acceleration sensor chip can be expressed as space motion the size of three mutually perpendicular direction acceleration, and shows with correspondent voltage value size, passes to microprocessor by the SPI mode.Microprocessor can be adjusted the amplification process of PPG signal based on these signals, and removes motion noise in the PPG signal by the method for adaptive-filtering; Adopted super low-power consumption microprocessor MSP430FG439, every 1MHz under the CPU mode of operation, electric current are 300 μ A, minimum current 0.1 μ A under the CPU sleep pattern.In addition, the peripheral hardware that enriches that system contains is promptly simplified circuit design, and the reduction system volume has been avoided extraneous electromagnetic interference again, improves systematic function; The low-consumption wireless radio-frequency transmissions chip CC2500 that system adopts can transmit data efficiently based on the ZIGBEE agreement.
Claims (7)
1. blood oxygen saturation monitoring device based under the kinestate, comprise: PPG signal generation module, signal processing module, communication module and human-computer interaction module, it is characterized in that, also comprise: the motor message generation module, the motor message generation module acceleration magnitude of transmission people soma on three mutually perpendicular directions in space that link to each other with signal processing module, the PPG signal generation module PPG signal under transmission HONGGUANG and the infrared light that links to each other with signal processing module, communication module link to each other with signal processing module transmission blood oxygen signal and heart rate information, human-computer interaction module link to each other with signal processing module transmission of control signals and display result information;
Described motor message generation module is an acceleration transducer.
2. blood oxygen saturation monitoring device based under the kinestate according to claim 1, it is characterized in that, described PPG signal generation module comprises: an infrared diode, a near infrared diode and a photodiode, wherein: infrared diode and near infrared diode reverse parallel connection, infrared diode all links to each other with signal processing module with near infrared diode, and photodiode links to each other with signal processing module.
3. blood oxygen saturation monitoring device based under the kinestate according to claim 1, it is characterized in that, described signal processing module comprises: microprocessor, the photoelectricity drive circuit, the amplification filtering circuit, power circuit and memory device, wherein: the photoelectricity drive circuit links to each other with PPG signal generation module and transmits the luminous current signal of control, the photoelectricity drive circuit links to each other with microprocessor to transmit and drives signal, the amplification filtering circuit links to each other with PPG signal generation module and transmits the PPG signal, microprocessor links to each other with the amplification filtering circuit and transmits the amplification filtering signal, microprocessor links to each other with the motor message generation module and transmits the acceleration signal of three directions, microprocessor links to each other with memory device and transmits blood oxygen signal and heart rate information, microprocessor links to each other with power circuit and transmits power information, microprocessor link to each other with communication module transmission blood oxygen signal and heart rate information, microprocessor link to each other with human-computer interaction module transmission of control signals and display result information;
Described microprocessor is provided with analog-digital converter.
4. blood oxygen saturation monitoring device based under the kinestate according to claim 1, it is characterized in that, described communication module comprises: wire communication submodule and radio communication submodule, wherein: the wire communication submodule all links to each other with signal processing module with the radio communication submodule and transmits blood oxygen and heart rate information.
5. blood oxygen saturation monitoring device based under the kinestate according to claim 4, it is characterized in that, described wire communication submodule comprises: photoelectric isolating device and RS232 serial ports, wherein: photoelectric isolating device links to each other with signal processing module and transmits blood oxygen and heart rate information, and photoelectric isolating device links to each other with the RS232 serial ports and transmits blood oxygen and heart rate information.
6. blood oxygen saturation monitoring device based under the kinestate according to claim 4, it is characterized in that, described radio communication submodule is based on the less radio-frequency transmitter module of ZIGBEE agreement, its link to each other with signal processing module wireless transmission blood oxygen and heart rate signal.
7. blood oxygen saturation monitoring device based under the kinestate according to claim 1, it is characterized in that, described human-computer interaction module comprises: button and lattice lcd, wherein: button links to each other with signal processing module and transmits control information, and lattice lcd links to each other with signal processing module and shows blood oxygen and heart rate result.
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| CN2010101364492A CN101803925B (en) | 2010-03-31 | 2010-03-31 | Monitoring device of blood oxygen saturation in motion state |
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