CN101564324B - Minisize storage device for oral cavity activity prosthesis - Google Patents

Minisize storage device for oral cavity activity prosthesis Download PDF

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Publication number
CN101564324B
CN101564324B CN2008100366633A CN200810036663A CN101564324B CN 101564324 B CN101564324 B CN 101564324B CN 2008100366633 A CN2008100366633 A CN 2008100366633A CN 200810036663 A CN200810036663 A CN 200810036663A CN 101564324 B CN101564324 B CN 101564324B
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China
Prior art keywords
oral cavity
storage device
administration
activity prosthesis
prosthesis
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Expired - Fee Related
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CN2008100366633A
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Chinese (zh)
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CN101564324A (en
Inventor
魏斌
潘瑾
宫耀
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Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
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Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
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Priority to CN2008100366633A priority Critical patent/CN101564324B/en
Publication of CN101564324A publication Critical patent/CN101564324A/en
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Publication of CN101564324B publication Critical patent/CN101564324B/en
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Abstract

The invention relates to a minisize storage device for an oral cavity activity prosthesis, which is formed by an inner layer and an outer layer which are mutually sleeved and overlapped. The upper part of the inner layer forms an opening shape, the central part is hollow, and a piece of one-way through membrane can be stuck and placed on the inner face of the inner layer; and the outer layer formsan inverse cup shape, the top end is closed, and the outer layer is sleeved on the outer surface of the inner layer. The invention is applied to local administration of oral mucous membrane, is a new oral mucous membrane administration carrier, is different from systemic administration and previous mucous membrane administration, provides a stable and reliable mucous membrane administration route , better achieves controlled release, slow release or synergy of medicines, and provides a new administration mode for use of the medicines in hardwires.

Description

A kind of minisize storage device that is used for oral cavity activity prosthesis
[technical field]
The present invention relates to the stomatology field, specifically, is a kind of minisize storage device that is used for oral cavity activity prosthesis.
[background technology]
The oral mucosa administration is different with the whole body administration, can avoid gastrointestinal tract that medicine is destroyed and liver first-pass effect, directly absorbs to get in the body; For the local inflammation of oral cavity, throat, oral mucosa administration more effective.The oral mucosa administration generally includes medicine buccal and pad pasting administration, and wherein, buccal generally is along with tablet progressively dissolves and onset, and during the pad pasting administration, medicine acts on positions such as lip mucosa or cheek mucosa with various forms of pad pastings.Pad pasting generally has three-decker, and internal layer is the adhesion layer that contains binder, directly contacts with oral mucosa, and skin is an inert layer, and limit drug outwards discharges, and the centre is a medicine layer.In recent years; Also have the scholar to propose to contain the mode of bag administration; Contain bag administration and be the medicine of processing (tablet, granule, pill or powder) is enclosed in the pouch that filtration arranged; Pouch places buccal vestibule ditch or Sublingual, sees through bag film saliva and can infiltrate in the bag, and dissolved drug also can be infiltrated the oral cavity.
Oral cavity buccal, the dissolubility of medicine are difficult to control, and easy mistake gulps down, and its dosage form also can only be confined to tablet; The bonding of pad pasting administration adhesion layer and oral mucosa is a key, is difficult to obtain ideal adhesive effect on moistening surface, with the effect that directly has influence on medicine; Though contain the less-restrictive of bag administration to pharmaceutical dosage form, also have tangible foreign body sensation, and how properly fixing also be a problem anxious to be solved.
Activity prosthesis refers generally to traditional detachable dental prostheses, appliance and prosthesis etc., and this type of dummy is made up of artificial tooth, snap ring, base, connector etc. usually, and the patient can pluck voluntarily and wear.Activity prosthesis is by clinician's design and produce model, is made by special skilled worker, has had sophisticated processing technique and manufacturing technology.Do not see at present report as yet at activity prosthesis indoor design minisize storage device.
[summary of the invention]
The objective of the invention is to provide a kind of new oral administration carrier and approach, a kind of minisize storage device that is used for oral cavity activity prosthesis is provided.
For realizing above goal of the invention, the technical scheme that the present invention takes is:
A kind of minisize storage device that is used for oral cavity activity prosthesis is formed by inside and outside two-layer intussusception, and wherein, the top of internal layer is opening-like, and its middle body is a hollow structure, and skin is shaped as one and is inverted cup-shaped, and top closure is enclosed within the outer surface of internal layer.
This device is that material is processed by dental metal, and skin links to each other with activity prosthesis, and it can be produced in batches in advance, processes finished product or semi-finished product; The internal layer middle body of this device is a hollow, and medicine or other article, no solid shape, shape such as cylinder, cuboid, square etc. can be placed by central authorities; The hollow space of this device communicates with the external world through inside and outside base two-layer and activity prosthesis through micropore; After this device was inserted activity prosthesis, its skin was linked as integral body through certain way and activity prosthesis, to guarantee its stable bond, can adopt modes such as sleeve, half precision are adhered to, magnetic attachment; Can telescope crown maintenance mode be example, interior hat can be finished product, and outer hat can be plastics semi-finished product or post-production; Design different supplementary structures according to pharmaceutical properties: to volatile medicine, can paste the unidirectional penetrating film of placement a slice,, allow volatile medicine in the oral cavity, to volatilize from the locker room by unidirectional penetrating film at interior hat inner face; To solubility drug (buccal),, when guaranteeing activity prosthesis intensity, allow the two-way flow of saliva and medicine in the metal net shaped structure of activity prosthesis tongue lateral layout; To the medicine that the need mucosa absorbs, open activity prosthesis tissue surface, or by unidirectional penetrating film, the locker room directly contacts with the tissue surface mucosa, guarantees that the medicine unidirectional osmosis gets into mucosa; The mode that this device is presented in the activity prosthesis has 2 kinds, and insert with buccal aspect for tissue surface and insert, be main with the former, and this device is when shirking in activity prosthesis, the patient can take out by instruments such as probes easily voluntarily.
A kind of good effect that is used for the minisize storage device of oral cavity activity prosthesis of the present invention is:
(1) this device is through the reconstruction to the oral cavity activity prosthesis structure; On hardware, create a kind of new oral mucosa drug administration carrier; With whole body administration and mucosal drug delivery was different in the past, more reliable and stable mucosal drug delivery approach is provided, reach controlled release, slow release or the potentiation of medicine better;
(2) this device can make medicine with saliva limited contacting take place, and avoids medicine dissolution too fast, avoids mistake to gulp down, and the use of pharmaceutical dosage form is not confined to tablet yet, can also use liquor, paste etc.
[description of drawings]
The structural representation of Fig. 1 storage device of the present invention;
Fig. 2 is used for the sketch map of the inner storage device of oral cavity activity prosthesis.
The implication that each label is corresponding among the figure is: 1, support, 2, circular hole, 3, interior hat, 4, outer hat, 5, unidirectional penetrating film.
[specific embodiment]
Below in conjunction with accompanying drawing the present invention is provided a kind of specific embodiment that is used for the minisize storage device of oral cavity activity prosthesis, the invention is not restricted to the embodiment that is provided simultaneously.
Embodiment 1
Referring to accompanying drawing 1 and 2.At first need confirm to lay the position of storage device, generally design, enough spaces arranged, not influence the structure and the intensity of activity prosthesis simultaneously to guarantee it in the activity prosthesis thickness.In the present embodiment, activity prosthesis is a removable partial denture, is that example is described technical scheme of the present invention with the telescope crown maintenance.
(1) hat is made in: interior hat 3 finished productizations are metal or plastics; Interior hat is cylinder, and outer surface grinds through parallel beveller, and cohesion degree is the 6-8 degree, uniform thickness 3mm; The sealing of interior hat one end, towards alveolar ridge crest, there is groove in central authorities, the convenient interior rotation of being preced with; The other end is open, and interior crown height degree can close the gum footpath according to edentulous region and highly grind and change;
Hat 3 height and placement locations after grinding, grind a circular aperture 2, diameter 2mm, and sanding and polishing with the 1-1.5mm round bur in interior hat side in confirming;
(2) placement of unidirectional penetrating film: to the medication characteristic of some drugs; Can paste the unidirectional penetrating film 5 (about 3 * 3mm) of placement a slice at interior hat 3 inner faces; When medicine discharges from inside to outside, can prevent effectively that other material of saliva and oral cavity from flowing into the locker room;
(3) modelling: work model is placed on the visualizer, to confirm the whole path of insertion of artificial tooth;
(4) make fusible pattern: with sticky wax hat 3 in the metal is fixed on the model, fills and leads up recessedly according to drawn survey line, turn over the system refractory model;
(5) outer hat and rack making, according to the outer hat 4 of cohesion degree making of interior hat 6-8 degree, face shaping is inverted cup-shaped as one, top closure, other end open surface is preced with 3 outer surface to alveolar ridge crest in being enclosed within, and driving fit between the inside and outside hat can obtain good maintenance power; Link into an integrated entity with the support wax pattern when making outer hat wax pattern, support 1 is in order to increase the intensity of artificial tooth at this place, to avoid because of hollow design formation weak spot; Outer hat tongue side is made a circular aperture, diameter 2mm; Insert sprue-way, embedding, casting, grinding and buffing by conventional method then;
(6) the retainer examination is closed: metal rack that completes 1 and interior hat 3 examinations are closed, and inspection adaptation between the two, the goodness of fit between the aperture, and whether can rotate freely;
(7) making of other part of artificial tooth: make wax pattern, one aperture also arranged in artificial tooth tongue side group support corresponding position, can with outer hat 4, interior hat 3 two-way traffics; Adorn box, dewax, filling, heat treatment, open box, polishing and polishing by conventional steps, accomplish whole artificial tooth and make;
Be preced with 3 in noting before the dress box, must taking out, and be full of with silicone rubber, the destruction of hat elaboration in can avoiding at this place;
(8) placement of medicine and release: interior hat 3 inside are hollow, can directly place medicine, or by the penetrating film that interior hat inner face is placed, reach the slow release and the controlled release of medicine; The patient uses probe, and hat 3 takes out and place medicine and cleaning with interior hat 3 easily from outer hat 4 in aperture probes into.

Claims (5)

1. a minisize storage device that is used for oral cavity activity prosthesis is characterized in that, is formed by inside and outside two-layer intussusception, and wherein, the top of internal layer is opening-like, and middle body is a hollow structure; Skin is shaped as one and is inverted cup-shaped, is enclosed within the outer surface of internal layer; And middle body communicates with the external world through inside and outside base two-layer and activity prosthesis through micropore, and said middle body is the locker room that is used to place medicine.
2. a kind of minisize storage device that is used for oral cavity activity prosthesis according to claim 1; It is characterized in that; The inner face of described internal layer is pasted and is placed the unidirectional penetrating film of a slice; This unidirectional penetrating film allows volatile medicine to volatilize in the oral cavity from said locker room, can prevent that other material of saliva and oral cavity from flowing into the locker room simultaneously.
3. a kind of minisize storage device that is used for oral cavity activity prosthesis according to claim 1 is characterized in that described skin is linked as integral body through sleeve and activity prosthesis.
4. a kind of minisize storage device that is used for oral cavity activity prosthesis according to claim 1 is characterized in that, described skin adheres to activity prosthesis through half precision and is linked as integral body.
5. a kind of minisize storage device that is used for oral cavity activity prosthesis according to claim 1 is characterized in that described skin is linked as integral body through magnetic attachment and activity prosthesis.
CN2008100366633A 2008-04-25 2008-04-25 Minisize storage device for oral cavity activity prosthesis Expired - Fee Related CN101564324B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2008100366633A CN101564324B (en) 2008-04-25 2008-04-25 Minisize storage device for oral cavity activity prosthesis

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Application Number Priority Date Filing Date Title
CN2008100366633A CN101564324B (en) 2008-04-25 2008-04-25 Minisize storage device for oral cavity activity prosthesis

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CN101564324A CN101564324A (en) 2009-10-28
CN101564324B true CN101564324B (en) 2012-07-25

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103961053A (en) * 2014-05-19 2014-08-06 闫亚平 Mouth rehabilitation device
CN113440285B (en) * 2021-06-12 2023-06-30 杭州口腔医院集团有限公司 Denture for oral repair and denture bridge fusion method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1729503A1 (en) * 1990-03-19 1992-04-30 Научно-инженерный центр автоматизированных биотехнических систем "Сонар" Института кибернетики АН УССР Dental prosthesis
US6068475A (en) * 1999-02-11 2000-05-30 Stoyka, Jr.; Frank S. Flavored and medicated therapeutic mouthpiece
WO2002019937A2 (en) * 2000-09-05 2002-03-14 Technion Research And Development Foundation Ltd. Hydrogel incorporated with bone growth promoting agents for dental and oral surgery
CN1440730A (en) * 2002-11-13 2003-09-10 张佐 Occlusion jacket for treating tooth sensitiveness

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1729503A1 (en) * 1990-03-19 1992-04-30 Научно-инженерный центр автоматизированных биотехнических систем "Сонар" Института кибернетики АН УССР Dental prosthesis
US6068475A (en) * 1999-02-11 2000-05-30 Stoyka, Jr.; Frank S. Flavored and medicated therapeutic mouthpiece
WO2002019937A2 (en) * 2000-09-05 2002-03-14 Technion Research And Development Foundation Ltd. Hydrogel incorporated with bone growth promoting agents for dental and oral surgery
CN1440730A (en) * 2002-11-13 2003-09-10 张佐 Occlusion jacket for treating tooth sensitiveness

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