CN101485440B - Method for producing ion release type gelating product for sobering-up and inhibiting food ingredient absorption and product - Google Patents
Method for producing ion release type gelating product for sobering-up and inhibiting food ingredient absorption and product Download PDFInfo
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Abstract
The invention provides an ion-release type gelation method for alleviating intoxication and inhibiting food compositions from being absorbed, and a product thereof, which belongs to the technical field of food. The ion-release type gelation method for alleviating intoxication and inhibiting food compositions from being absorbed is characterized in that a human body takes in a mixture containing a calcium source and gel forming matter; under the action of acidic red wine or gastric acid, ethanol or food compositions in intestines and stomach are combined with the gel forming matter and calciumions into composite gel; and the gel forming matter is pectin or alginate. Experiment proves that the product provided according to the method can obviously inhibit ethanol from being absorbed in thehuman body and shorten the detention time of ethanol in the human body. The product can be used for drinking population for preventing intoxication and treat drunks, as well as the population needing to control the absorption of the food compositions.
Description
Technical field
The present invention relates to food technology field, particularly relate to relieving the effect of alcohol and suppressing method and the goods that COF absorbs of a kind of producing ion release type gelating product.
Background technology
Along with the raising of The development in society and economy and people's living standard, and spirits culture is in the influence of China, and it is very general drinking in China, but drink the person had very big infringement, and particularly a large amount of drinks.Therefore occasion in social activity must be drunk again sometimes, invents a kind ofly can relieve the effect of alcohol and reduce the product of ethanol to injury of human, and the needs of drinking in the time of can satisfying social activity can be protected healthy again.Relieving the effect of alcohol at present has three kinds of modes, and the one, reduce or suppress the absorption of ethanol; The 2nd, through accelerating ethanol metabolism in vivo becoming water and carbon dioxide, want to accelerate activity and the content that ethanol metabolism in vivo need increase L-AD and acetaldehyde dehydrogenase, this process is slower.The 3rd, through lung's exhalation, RE (diuresis and great quantity of water drinking) and skin perspiration (drink hot water and raising indoor temperature) eliminating, this approach at most only accounts for 10% of absorption ethanol total amount, is not the best approach that relieves the effect of alcohol.And the absorption of inhibition or minimizing ethanol can be brought into play the effect of relieving the effect of alcohol sooner.
It mainly is to have Chinese medicine materials such as FI puerariae, the root of kudzu vine, glossy ganoderma, Raisin Tree Seed, Radix Isatidis to process that some disintoxicating products are arranged in the market; Significant feature mechanism is the hepatoprotective effect through oxidation and removing free radicals; Might accelerate ethanol metabolism in vivo after absorbing in vivo, little to the inhibitory action of ethanol absorption.
In the drunk method of prevention among the people is exactly at the earlier edible before oily food of drinking, like fat meat, pork leg etc., or milk drink, utilize the fatty stodgy characteristic protection stomach in the food, to prevent the ethanol infiltration coat of the stomach.In addition, the shagreen of guava part also can be brought into play same effect.Empty stomach is drunk or carbonated drink, soda water and wine is drunk together, can make stomach under the situation that does not have protection, accelerate the infiltration rate of ethanol, makes liver have little time detoxifcation, and concentration of alcohol increases rapidly and causes drunk.
But said method is not clearly to preventing effect drunk and that relieve the effect of alcohol, and effect slowly, though some mode has utilized the principle that suppresses ethanol absorption to reach the effect of relieving the effect of alcohol, effect is also not obvious; Though drunk method and the product of prevention that suppresses ethanol absorption arranged at present, also only obvious to liquor and foreign wine effect, and the relieving alcoholism and preventing drunkenness of red wine is not had obvious effects.
Summary of the invention
To the deficiency in the above-mentioned technical field; The present invention provides relieving the effect of alcohol of a kind of producing ion release type gelating product and suppresses method and the goods that COF absorbs; Particularly suppress ethanol absorption in vivo in the red wine; Reaching the effect of relieving the effect of alcohol and increasing capacity for liquor, also play liver-protective effect simultaneously, in addition also clearly to the absorption that suppresses liquor and antialcoholism action.
The relieving the effect of alcohol and suppress the method that COF absorbs of a kind of producing ion release type gelating product; It is characterized in that: human body is taken in and is contained calcium source and the mixture that becomes the glue material; Under the effect of acid red wine or hydrochloric acid in gastric juice; Ethanol in the stomach or COF combine to form plural gel with becoming glue material and calcium ion, and said one-tenth glue material is pectin or alginate.
Said pectin is a kind of of HM or LM.
Said alginate is sodium alginate, potassium alginate or ammonium alginate.
Described calcium source is calcium sulfate or calcium monohydrogen phosphate.
Relieving the effect of alcohol and suppress the goods that method that COF absorbs makes according to above-mentioned producing ion release type gelating product; It is characterized in that comprising into glue material, acid-base modifier, calcium source and school flavor agent; Becoming glue material, calcium source, school flavor agent weight ratio is 1: 0.01-0.3: 0-40, the consumption of acid-base modifier are that pH transfers at 6.5-8.5.
Said one-tenth glue material, calcium source, school flavor agent weight ratio are 1: 0.07-0.2: 5-20, best pH are 6.9-7.5.
Described acid-base modifier is a kind of in sodium acid carbonate, sodium carbonate, potash, dipotassium hydrogen phosphate, sodium hydrogen phosphate, tertiary sodium phosphate, tripotassium phosphate, natrium citricum, potassium citrate, NaOH, potassium hydroxide, gluconic acid δ lactones, sodium dihydrogen citrate, the sodium sesquicarbonate.
The flavor agent of described school is sweetener, fruits and vegetables powder and/or Juice.
Described sweetener is granulated sugar, glucose, sucrose, fructose, maltose, lactose, maltitol, lactitol, xylitol, sorbierite, antierythrite, one or more of dithiothreitol (DTT); Said fruits and vegetables powder; Juice comprises apple; Strawberry; Cherry; "Hami" melon; Banana; Lichee; Fruit of Panax ginseng; Mango; Pomegranate; Olive; Sugarcane; Hawthorn; Pears; Oranges and tangerines; Watermelon; Muskmelon; Peach; Apricot; Passionflower; Kiwi berry; Shaddock; Pineapple; Wild jujube; Beet; Tomato; Carrot; Cucumber; Pumpkin; Wax gourd; Chinese cabbage; Cabbage; Cauliflower; Persimmon; Balsam pear; Water chestnut; Ternip; Eggplant; Green pepper; Celery; Spinach; Bright lotus root; Garlic; One or more compound fruit and vegetable powder of onion; Juice.
Said products is drunk in prevention, relieve the effect of alcohol and suppress the application aspect the absorption of COF.
The present invention adopts scientific principles; Under acid red wine or hydrochloric acid in gastric juice condition; Discharge calcium ion, make ethanol or COF be combined into plural gel shape thing, make free ethanol and COF reduction in the stomach with becoming the glue material; Reduce interior absorption of body of ethanol and COF, thereby play the effect of sobering up and improving capacity for liquor and the absorption of control COF.
The present invention is based on the ion freezing mechanism of pectin and alginate, pectin and alginate are that the most frequently used edible gel, particularly LM or alginate solution are under the situation that calcium ion exists; Molecule crosslinked formation gel, under the neutral environment condition, the calcium in the calcium source is in bonding state; Therefore product is in that liquid condition can not be solidified and after acid red wine mixes, makes product be in acid condition; At this moment calcium ion discharges, and makes pectin or alginate take place crosslinked and the formation gelling material, makes free ethanol molecule form plural gel shape thing; Suppress interior absorption of body of ethanol, thereby reach the effect of relieving the effect of alcohol, sobering up.
The goods that relieve the effect of alcohol provided by the invention add sweetener, fruits and vegetables powder and/or Juice as the school agent of distinguishing the flavor of, and have increased the agreeable to the taste sense and the nutritive value of these goods.
The present invention's goods that relieve the effect of alcohol can be electuary, beverage, tablet and gastric-dissolved capsule, take in before drinking these goods can prevent drunk with improve capacity for liquor, after drinking, drink into the goods that originally the relieve the effect of alcohol restoring consciouness of can relieving the effect of alcohol, reduce the burning sensation of alcohol to stomach.These goods are because its mechanism of action also can play inhibitory action to the absorption of food, such as the absorption of control fat, cholesterol, sugar.
Goods of the present invention only run into hydrochloric acid in gastric juice or acid wine liquid could form gelinite, and after being ingested, parcel ethanol forms frangible gel in stomach and under the interaction of acid red wine or hydrochloric acid in gastric juice, and free ethanol molecule is reduced; Gel forms thicker food layer on the small intestine surface after getting into small intestine, thereby the absorption of the inhibition or the ethanol that slows down reaches and relieves the effect of alcohol, increases capacity for liquor, is applicable to prevent the treatment drunk and drunk person.External ethanol combines the edible the present invention's goods that relieve the effect of alcohol that also prove of test and volunteer to have and increase capacity for liquor and the effect of relieving the effect of alcohol, and can be used to the crowd of drinking and prevent drunk and the treatment drunk person, can also play liver-protective effect.External COF combines test to show that these article ability and COF combine, and suppress the absorption of sugar and fatty material.
Description of drawings
Fig. 1, aspiration eater drink behind the 56% strong, colourless liquor distilled from sorghum 100ml in the breath alcohol concentration (mg/100ml) in time (minute) change curve, the abscissa express time (minute), ordinate is represented alcohol concentration (mg/100ml).
Fig. 2, aspiration eater drink behind 56% strong, colourless liquor distilled from sorghum 100ml and the 200ml sample in the breath alcohol concentration (mg/100ml) in time (minute) change curve, the abscissa express time (minute), ordinate is represented alcohol concentration (mg/100ml).
Fig. 3, aspiration eater drink behind the 13.5% claret 200ml in the breath alcohol concentration (mg/100ml) in time (minute) change curve, the abscissa express time (minute), ordinate is represented alcohol concentration (mg/100ml).
Fig. 4, aspiration eater drink behind 13.5% claret 200ml and the 200ml sample in the breath alcohol concentration (mg/100ml) in time (minute) change curve, the abscissa express time (minute), ordinate is represented alcohol concentration (mg/100ml).
The specific embodiment
In conjunction with embodiment the present invention is done further detailed description.
Embodiment 1
Embodiment 2
LM 10 grams, sodium acid carbonate 0.09 gram, calcium monohydrogen phosphate 0.75 gram, granulated sugar 100 grams, pumpkin powder 30 grams dissolve in 1000ml water, every bottle of 100ml packing, high-temperature sterilization.
Embodiment 3
Ammonium alginate 10 grams, natrium citricum 0.6 gram, calcium monohydrogen phosphate 0.15 gram, granulated sugar 200 grams, pineapple powder 30 grams, every bag 15 gram packings behind the mixed grinding.
Embodiment 4
Embodiment 5
Potassium alginate 10 grams, sodium acid carbonate 0.06 gram, calcium sulfate 0.75 gram, granulated sugar 50 grams, glucose 50 grams, carrot meal 30 grams, every bag 15 gram packings behind the mixed grinding.
Embodiment 6
Embodiment 7
Embodiment 8
Sodium alginate 10 grams, sodium acid carbonate 0.3 gram, calcium monohydrogen phosphate 0.75 gram, mango powder 80 grams, every bag 15 gram packings behind the mixed grinding.
The experimental example effect assessment
Goods among the above embodiment are as being solid, and the ratio that then becomes the glue material to add 100ml water in 1g in the component is used for following test after dissolving fully, and liquid directly is used for test.
1. become the colloidality evaluation
Getting aforesaid liquid 5ml adding volume respectively is in the test tube of 10ml, adds 13.5%, 12% claret 5ml then respectively, shakes up immediately, observes into the glue situation after 5 minutes.Result such as table 1.
Table 1
| Wine concentration | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 | Embodiment 7 | Embodiment 8 |
| 13.5％ | ++++ | ++++ | +++ | ++++ | ++++ | ++++ | ++++ | ++++ |
| 12％ | ++++ | ++++ | +++ | ++++ | ++++ | ++++ | ++++ | ++++ |
+ expression forms gel
Above-mentioned experiment shows, the goods that relieve the effect of alcohol of the present invention add acid red and can form gelinite after drinking, can reduce ethanol free in the stomach, suppresses interior absorption of body of ethanol.
2. the ethanol conservation rate is estimated
Blank: the mixed liquor of the hydrochloric acid of 56% ethanol 1ml and 0.2ml pH=2 or 13.5% red wine 1ml and 2ml distilled water join in the 10ml test tube.
Test: the goods liquid 1ml that relieves the effect of alcohol that makes that the mixed liquor of the hydrochloric acid of 56% ethanol 1ml and 0.2ml pH=2 or 13.5% red wine 1ml add above embodiment joins mixing in the 10ml test tube; 1000RPM is centrifugal 20 minutes after 10 minutes; Collect supernatant and join in the 1ml distilled water, through suitably adopting ethanol content in the gas chromatography determination liquid after the dilution.The ethanol conservation rate calculates by following formula:
Ethanol conservation rate (%)=[(blank value-test value)/blank value] * 100%
Result such as table 2:
Table 2
| Wine concentration | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 | Embodiment 7 | Embodiment 8 |
| 13.5％ | 95％ | 93％ | 90％ | 95％ | 98％ | 96％ | 99％ | 96％ |
| 56％ | 96％ | 94％ | 88％ | 90％ | 93％ | 95％ | 96％ | 93％ |
Above-mentioned experiment showed, in the gelinite material is enclosed with ethanol, makes free amount of alcohol reduce, and the ethanol conservation rate is high, explains that the ethanol content that wraps up in the gelinite is high.
3. to the gelling of COF
1) to the gelling of sugar: getting aforesaid liquid 5ml respectively, to add volume be in the test tube of 15ml, adds 60% sugar solubility 4ml then, adds the hydrochloric acid 1ml of pH=2 again, and mixing is observed into the glue situation after 5 minutes immediately.Result such as table 3:
Table 3
| Sugar concentration | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 |
| 60％ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ |
| Sugar concentration | Embodiment 7 | Embodiment 8 | ||||
| 60％ | ++++ | ++++ |
+ expression forms gel
Above-mentioned experiment shows that goods of the present invention can form gelinite after adding granulated sugar under the condition of simulation hydrochloric acid in gastric juice, has reduced free glycan molecule, therefore can suppress to delay to absorb in the sugared body.
2) the one-tenth colloidality of yolk is estimated: getting aforesaid liquid 5ml adding volume respectively is in the test tube of 15ml, adds 60% yolk solution 4ml then, adds the hydrochloric acid 1ml of pH=2 again, and mixing is observed into the glue situation after 5 minutes immediately.Result such as table 4:
Table 4
| Yolk | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 |
| 60％ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ |
| Yolk | Embodiment 7 | Embodiment 8 | ||||
| 60％ | ++++ | ++++ |
+ expression forms gel
Above-mentioned experiment shows that goods of the present invention can form gelinite after adding yolk under the condition of simulation hydrochloric acid in gastric juice, reduced the CHF in the yolk, therefore can suppress to delay interior absorption of body of cholesterol.
3) the one-tenth colloidality of vegetable oil is estimated: getting aforesaid liquid 5ml adding volume respectively is in the test tube of 15ml, adds vegetable oil 4ml then, adds the hydrochloric acid 1ml of pH=2 again, and mixing is observed into the glue situation after 5 minutes immediately.Result such as table 5:
Table 5
| Vegetable oil | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 |
| 100％ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ |
| Vegetable oil | Embodiment 7 | Embodiment 8 | ||||
| 100％ | ++++ | ++++ |
+ expression forms gel
Above-mentioned experiment shows, under the condition of simulation hydrochloric acid in gastric juice, can form gelinite behind the goods adding vegetable oil of the present invention, reduces free aliphatic acid, therefore can suppress to delay interior absorption of body of aliphatic acid.
4. volunteer's eating effect experiment
Adopt the goods of embodiment 2 to be used for this experiment.
Select the age in 22-45 year, body weight has low alcohol consumption custom person at ordinary times at the healthy male of 55-75 kilogram, is divided into 4 groups at random.The 1st group: in 1-3 minute, drink 56% strong, colourless liquor distilled from sorghum 100ml, drink common fruit juice simultaneously; The 2nd group: in 1-3 minute, drink 56% strong, colourless liquor distilled from sorghum 100ml, drink 200ml goods of the present invention simultaneously; The 3rd group: in 1-3 minute, drink 13.5% claret 200ml, drink common fruit juice simultaneously; The 4th group: in 1-3 minute, drink 13.5% claret 200ml, drink 200ml goods of the present invention simultaneously.Before drinking with drink finish in back 1 hour every at a distance from after 5 minutes, 1 hour every in mensuration expiration in 10 minutes alcohol content, till can not measuring.The calculating mean value as a result of each time point determining.
The result is following: experimental data is illustrated in drinks 56% strong, colourless liquor distilled from sorghum 100ml; Drink in the absence of goods of the present invention; The back breath of drinking contained very high alcohol concentration (Fig. 1) at 6 hours; And drink simultaneously under the situation of goods of the present invention, the content of alcohol is not than drinking obvious reduction in the breath, and the alcohol holdup time in vivo obviously shortens (Fig. 2).Drinking the 200ml red wine; Drink in the absence of sample, breath can be measured alcohol content in 120 minutes, was in the state of drinking (Fig. 3); And drink at the same time under the situation of this sample; Breath was not measured alcohol content in 15 minutes-150 minutes that observe, be in the non-state of drinking (Fig. 4), and the alcohol of the breath in 15 minutes is the cause that remains in alcohol in the oral cavity after drinking.Therefore, the present invention can obviously suppress to delay alcohol and absorb, and reduces BAC, and shortening alcohol is the holdup time in vivo.
The result that goods of the present invention are used in vitro test shows, these goods and liquor, red wine and COF mix after the back becomes colloid, the free molecule that can absorb in the food is reduced, so inhibition delay the absorption of COF.In vivo studies shows that the present invention can obviously suppress alcohol absorption in liquor and the red wine, reduces BAC, and shortening alcohol is the holdup time in vivo.These goods can be used to the crowd of drinking and prevent drunk and the treatment drunk person.
Claims (5)
1. the relieving the effect of alcohol and suppress the goods that COF absorbs an of producing ion release type gelating product, it consists of: LM 10 grams, dipotassium hydrogen phosphate 0.15 gram, calcium monohydrogen phosphate 0.75 gram, granulated sugar 150 grams, every bag 15 gram packings behind the mixed grinding.
2. the relieving the effect of alcohol and suppress the goods that COF absorbs an of producing ion release type gelating product, it consists of: ammonium alginate 10 grams, natrium citricum 0.6 gram, calcium monohydrogen phosphate 0.15 gram, granulated sugar 200 grams, pineapple powder 30 grams, every bag 15 gram packings behind the mixed grinding.
3. a producing ion release type gelating product relieves the effect of alcohol and suppresses the goods that COF absorbs; It consists of: potassium alginate 10 grams, sodium acid carbonate 0.06 gram, calcium sulfate 0.75 gram, granulated sugar 50 grams; Glucose 50 grams, carrot meal 30 grams, every bag 15 gram packings behind the mixed grinding.
4. a producing ion release type gelating product relieves the effect of alcohol and suppresses the goods that COF absorbs; It consists of: HM 10 grams, glucono-delta-lactone 0.06 gram, calcium monohydrogen phosphate 3 grams, granulated sugar 100 grams, litchi powder 30 grams, every bag 15 gram packings behind the mixed grinding.
5. the relieving the effect of alcohol and suppress the goods that COF absorbs an of producing ion release type gelating product, it consists of: sodium alginate 10 grams, sodium acid carbonate 0.3 gram, calcium monohydrogen phosphate 0.75 gram, mango powder 80 grams, every bag 15 gram packings behind the mixed grinding.
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| CN110787185A (en) * | 2019-11-26 | 2020-02-14 | 广东海洋大学 | Alcohol-dispelling liver-protecting hydrogel tablet and preparation method and application thereof |
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| CN102727514B (en) * | 2011-04-12 | 2016-04-13 | 熊慧 | For adsorbing preparation and the application thereof of ethanol and composition of food |
| CN102871117A (en) * | 2011-07-15 | 2013-01-16 | 张清 | Method and product for controlling absorption of food composition |
| CN103027295A (en) * | 2012-12-28 | 2013-04-10 | 青岛爱维互动信息技术有限公司 | Sobering agent |
| CN103478632B (en) * | 2013-09-17 | 2014-09-17 | 江西宇骏生物工程有限公司 | Fruit and vegetable health tablets and method for preparing same |
| JPWO2016104334A1 (en) * | 2014-12-25 | 2017-10-05 | 大正製薬株式会社 | Aqueous liquid beverage |
| CN106581684A (en) * | 2016-11-30 | 2017-04-26 | 王利华 | Method for forming wine/gastric juice stable interface, use of special material and special wine |
| CN109090585A (en) * | 2018-08-13 | 2018-12-28 | 万光瑞 | One kind relieves the effect of alcohol, protect stomach, protect liver, shield brain composition and preparation method thereof |
| CN114916666A (en) * | 2022-04-20 | 2022-08-19 | 杭州曼士元食品科技有限公司 | Composition for relieving alcoholism |
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| CN1620257A (en) * | 2001-12-20 | 2005-05-25 | 努特里奇亚有限公司 | Matrix-forming composition containing pectin |
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| CN110787185A (en) * | 2019-11-26 | 2020-02-14 | 广东海洋大学 | Alcohol-dispelling liver-protecting hydrogel tablet and preparation method and application thereof |
| CN110787185B (en) * | 2019-11-26 | 2021-08-27 | 广东海洋大学 | Alcohol-dispelling liver-protecting hydrogel tablet and preparation method and application thereof |
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Application publication date: 20090722 Assignee: Beijing Ricky virtue Technology Development Co., Ltd. Assignor: Zhang Qing Contract record no.: 2015990000229 Denomination of invention: Method for producing ion release type gelating product for sobering-up and inhibiting food ingredient absorption and product Granted publication date: 20121226 License type: Exclusive License Record date: 20150424 |
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Effective date of registration: 20180625 Address after: 100085 room 1, room 5, Haidian District trail Road, Beijing, Beijing Patentee after: Beijing Ricky virtue Technology Development Co., Ltd. Address before: 100029 1502, 14 floor, three District, anzhen Li, Chaoyang District, Beijing. Patentee before: Zhang Qing |
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