CN101384237B - A container for a blister package - Google Patents
A container for a blister package Download PDFInfo
- Publication number
- CN101384237B CN101384237B CN2007800059446A CN200780005944A CN101384237B CN 101384237 B CN101384237 B CN 101384237B CN 2007800059446 A CN2007800059446 A CN 2007800059446A CN 200780005944 A CN200780005944 A CN 200780005944A CN 101384237 B CN101384237 B CN 101384237B
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- China
- Prior art keywords
- container
- blister package
- user
- compartment
- ejecting structure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
- B65D83/0445—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments
- B65D83/0463—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments formed in a band or a blisterweb, inserted in a dispensing device or container
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
- A61J7/0436—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system resulting from removing a drug from, or opening, a container
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- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- Medical Informatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The present invention provides a container for storing a blister package and for managing medication with a pharmaceutical composition comprised in the blister package. The container comprises a housing which forms a compartment for the blister package, means for indicating towards a user an appropriate time of accessing the blister package, and means for detecting a users access to a blister package in the compartment. The blister package is moved into and out of the compartment by means of an ejection structure to which the blister package may be fixed. The ejection structure facilitates an enhanced handling of the blister package during insertion and removal of the blister package and facilitates a more accurate indication of a user's access to the blister package.
Description
Technical field
The present invention relates to be used for the container of blister package (blister package); This blister package for example is used to hold the medicine (doses of a pharmaceutical composition) of multi-agent; This container comprises the housing of the compartment that is formed for blister package; Be used for device to the suitable time of user indication picked-up potion medicine, and the device that is used to detect user this blister package of visit and visits medicine thus.
Background technology
Blister package generally is transparent plastic mould, and it forms by peeling off or one or more cavitys of destructive paillon foil or cardboard sealing.Blister package typically is used to encapsulate and the medicine of displaying merchandise or packing multi-agent, confection, chewing gum or the like.Blister package sometimes is also referred to as blister package (bubblepack).
About having the blister package of medicine, there are allotter (dispenser) and container, it has time set and is used to notify user when to absorb medicament.Some already present systems automatically write down medicament from the removing of blister package, or the compliance (compliance) of the medicament that removes of record and the predetermined medication treatment plan of the medicine of being paid close attention to.User can for example accept to indicate when absorb the potion medicine or last time medicament incured loss through delay signal how long.
WO03/003970 discloses and a kind ofly has been used to discern the blister package with medicine, and WO99/43283 discloses a kind of device that is used to indicate the incident of taking.
Summary of the invention
An object of the present invention is to improve the existing container that is used for blister package.In first aspect, the invention provides the container of the type of being mentioned in a kind of background technology, wherein this container also comprises ejecting structure or exit structure, fixedly blister package on it." ejecting structure " and " exit structure " is appreciated that in description subsequently and is interchangeable statement.This ejecting structure can be shifted to the open position that is used for encapsulating structure is outwards shifted out this compartment, and can shift to the make position that is used for encapsulating structure is inwardly moved into this compartment.
Because blister package moves into and shift out compartment through ejecting structure, this ejecting structure forms the part of container, can avoid the sliding-contact between the container and blister package during blister package is inserted or shifted out from compartment fully.This makes the function can strengthen container, for example has the improved guiding of blister package turnover compartment, especially for the use of the blister package of dissimilar, size and condition.Because blister package receives guiding ground to insert compartment, user can be experienced the correct location of blister package in compartment more definitely, and the existence or the user that are used to detect blister package can be operated the pick off of the visit of blister package more reliably.In addition, avoid the direct sliding-contact between blister package and the container can strengthen protection, can avoid medicament because wearing and tearing and all of a sudden opened and expose to blister package.
Ejecting structure can be guided by the sliding-contact between ejecting structure surface and the surface of shell, for the ease of moving, can form sliding bearing or linear roller bearing at match surface.Ejecting structure preferably obtains guiding through linear slide rail in housing, this linear slide rail allows ejecting structure to move linearly with respect to housing, and the location of ejecting structure is preferably provided support by the frictional force between the surface of the surface of ejecting structure and housing.In one embodiment, ejecting structure moves forward and backward in a groove, and the size of this groove is suitable for receiving blister package ,-be that the groove that compartment passes through in the housing forms.For the ease of with in the blister package insertion groove, this groove can form the opening with chamfered edge or Chamfer Edge, and its guiding blister package gets into this groove.
This linear slide rail can limit end stop (end-stop), and ejecting structure surpasses being moved further of it with respect to housing and is prevented from.Prevented that thus ejecting structure from separating from housing.
User can for example detect through the supervision to blister package itself in device the visit of blister package, and this supervision realizes through mobile-initiated machinery, optics or other devices of blister package itself.Yet blister package possibly be of different sizes, type and condition.As an example, the size and dimension between the blister package maybe be different, and user possibly remove the part of blister package before remainder being inserted into blister package.Mobile difficulty and the inaccuracy of becoming that the condition of the variation of blister package makes the detection blister package.In one embodiment of the invention, through detecting the mobile of ejecting structure rather than keeping watch on the visit that blister package itself detects user.Thereby, can not receive type, size and the condition influence of blister package and obtain enhanced safety the detection of user visit.Can detect ejecting structure detects user with respect to any mechanical switch device, fluorescence detector, magnetic trigger switch or the magnetic induction device that move of housing visit through being arranged as.As an example, the visit of user can confirm that when ejecting structure moved along outside or inward direction, this mechanical switch was triggered through being embedded in the linear track or along the localized mechanical switch of linear track.
The visit of user also can detect optically, and the for example interruption through electromagnetic radiation beam is through being arranged in magnetosensitive switch or the electric induction on housing and ejecting structure one with respect to housing mobile-initiated by ejecting structure.
The visit of user also can be passed through alternatively interrecord structure of manual actuation, for example is obedient to press button and waits record.
For the clear indication that the visit that user is provided to user has been write down, this switch can provide the sense of touch indication maybe can provide indication through the sound that electricity or machinery produce.
In one embodiment, only ejecting structure along withdraw from approach axis in the visit of moving time record user of a direction.As an example, not record and record at ejecting structure and when blister package moves into compartment thus only when ejecting structure shifts out compartment of the visit of user.
In one embodiment; Container is suitable for storing blister package, and the multi-agent medicine is held in this blister package, for example pill, tablet, capsule, suppository, dragee, chewing gum, powder, particulate, colloid, liquid or the like; For example be used for non-orally using, for example be applicable to oral or the Sublingual use.If this composition is designed to take at interval by regular time; Be called " according to drug rehabilitation program " below; Promptly can not be too frequently or very little; It is auxiliary to be that user provides through compliant structure, and this compliant structure is suitable for time of indicating the last user visit to be taken place, and promptly when user is visited this blister package for the last time.Compliant structure can also be suitable for the time that the user visit was continued from last time.
In more advanced embodiment, compliant structure comprises automatically warns user about the information of drug rehabilitation program and in the time will taking medicament.As an example; Compliant structure can be suitable between attention state (attention state) and non-attention state, changing; Supposition user livery with medicament in this attention state, the supposition user waited for that this state changed to attention state before taking other medicament in non-attention state.Conversion from attention state to non-attention state can be triggered by timer, and this timer is programmed according to the drug rehabilitation program of the medicament that is used for being paid close attention to.Conversion from attention state to non-attention state can trigger through the visit of user, for example passes through the record that moves of ejecting structure.Thus when next medicament expires, the visit of user this timer that resets, it begins counting once more and is transformed into attention state.
In one embodiment, the visit of user only when compliant structure is in attention state by record.But compliant structure is in non-attention state, promptly also is not when taking the time of next medicament, the moving or the manual operation of press button this timer that can not reset of ejecting structure before next medicament expires, and this timer continues timing.In another embodiment, the visit of user is only write down by the manual operation press button when compliant structure is in attention state and reset timer thus.That is mobile this timer that can't reset of ejecting structure.If user moves blister package turnover container when compliant structure is in non-attention state, this has reduced the electric consumption of this device, and this characteristic is conserve batteries and further allow under the situation of reset timer not, to replace blister package thus.
In more advanced embodiment, compliant structure is suitable for reading drug rehabilitation program from blister package, for example reads technology through any electronics in the prior art, for example technology magnetic or light or the like.In one embodiment, container comprises a plurality of read sensors, for example is suitable for reading a plurality of medicaments drug rehabilitation program separately that is included in the blister package.In this embodiment, this pick off can also be used to write down the history of Drug therapy, and for example first agent medicine is taken at particular point in time, and second agent medicine is taken or the like at another time point.The feasible document based on the drug rehabilitation program that is included in some the different medicaments in the single blister package of this characteristic generates and is more prone to.
User can represent to obtain the expectation about the information of being obedient to very simple mode through using press button.As an example, user can be pressed pre-determined number, for example three times, to require the status information of compliant structure, promptly whether has arrived the time of new medicament or when has taken next medicament alternatively.
For indicate whether to user ejecting structure and thus blister package be not in closure state, container may further include second timer, it is suitable for period of confirming that ejecting structure is not in the close position.Can be only confirm that at timer ejecting structure has not been in the close position one during greater than the interval of predetermined time interval, compliant structure just can be transformed into non-attention state from attention state.
Attention state can pass through notification signal, such as light, sound or vibration signal and combination thereof, indicates user, and perhaps container can even transmit notification signal through wireless telecommunications, for example via Bluetooth
TMCommunication is sent to external device (ED).The wireless telecommunications of notification signal have promoted patient's telemonitoring, the people who for example looks after at hospital or the needs of being in.
User possibly not noticed notification signal; For example because noise or other situation; For conserve batteries and do not produce unnecessary interference, after non-attention state was transformed into attention state, notification signal can be used as repeating signal and transmits by scheduled time slot at compliant structure.In one embodiment, this scheduled time slot can increase between each transmits.As an example, in case compliant structure is transformed into attention state, one for example continues that the notification signal of 15s is transmitted, if container also is in attention state after 5 minutes, notification signal subsequently can be transmitted.For example after 15 minutes, another notification signal can be transmitted, or the like.
If user has been ignored these signals, for example after the repeating signal of some, container can be converted back to non-attention state automatically.In this case, container can write down for the shortage of this period and be obedient to labelling.According to the medicine Planning Directive for specific medication, some " correctly " time points subsequently in time are determined, and will be taken the specific interval between the i.e. user of " correctly " visit at this " correctly " time point place medicament.Container can be suitable for each visit that determines whether user at interval is established, and promptly for example whether ejecting mechanism is moved.If ejecting mechanism is moved, container writes down to this and writes down " being obedient to " at interval, if do not have, then writes down " shortage is obedient to " at interval to this.After the interval of some, from some being obedient to or lacking the quantity of being obedient to and to present to user or be sent to external device (ED) at interval through interface.
The quantity of in one period, being obedient to can be converted into the identifier that is more readily understood of being obedient to; Numerical fraction for example; Or be converted into through the signal of light emitting diode (LED) emission or the similar light on the outer surface of container; Colour coding for example, perhaps acoustical signal can be obedient in the period at the interval that comprises some or the code that lacks the quantity of being obedient to transmits according to indication.
As an example; In five records, be obedient to red light signal or the warning tones that record can cause sending to user more than a shortage, and in five records one or be less than a shortage and be obedient to green light signal or the non-warning tones that record can cause sending to user.Container can always calculate and comprise the compliance of fixed qty in the period at interval.Promptly new each time interval begins, and the evaluation of compliance is based on the interval formerly of nearest interval and fixed qty.This provides moving average, the average of promptly fixed period formerly.
In one embodiment, container comprises interface structure, for example based on UBS interface or the like, can communicate by letter with external computer system through this interface container.As an example, be obedient to data and can be sent to computer, for example at the computer in health center, so that monitoring medicine plan and compliance.Alternatively or extra, container can be suitable for wireless telecommunications or it can comprise interchangeable memory module, for example known SD memory module in the appliance and electronic.Can allow user will be obedient to data and send to external computer system through the mail of routine.
In order to increase the effective area of optical signal on container outer surface, light can be through producing such as the such illuminating device of LED, and it is arranged to transmit the light transversely in the prism (prism), and for example prism forms the part of the protecgulum of container.This prism can propagates light and is made signal more container is to be detected.
In one embodiment, prism can form drug rehabilitation program provided and the shape that be included in the type of the medicine in the blister package of indication.
This blister package can be fixed to ejecting structure through clamping device, and this clamping device comprises two parts that form groove, and wherein blister package is inserted in this groove.As an example, clamp device and can comprise relative to each other localized back member and adjacent front part, thereby bubble-cap clamp (blister card) can be received in therebetween.Back member and front part for example can with the mode of clip or clothes-pegs along close to each other or away from direction relative to each other move.The clamping device of clip shape can be set size with respect to this groove and is pressed onto together by the inner surface of groove from then member and front part, and wherein blister package is received in this groove.
In one embodiment, clamp the blister package that device is suitable for supporting such type, medicament wherein, for example tablet or the pill surface independently bulge or the cavity that are arranged in blister package.In this embodiment, in member and the front part of back comprises the clamping structure that is suitable at least in part around a bulge in the blister package surface at least.This clamping device especially prevents the rotation of blister package during ejecting mechanism turnover container.As an example, clamping device can comprise that its one or more outward flanges along blister package of one or more support profiles extend and prevent that thus blister package from rotating with respect to ejecting structure.This support profiles for example can comprise groove, and it receives the edge of blister package.
In one embodiment, container comprises detection means, and it is suitable for detecting the existence of the blister package that is fixed to ejecting structure.As an example, detection means can not have blister package to be present under the situation in the container to warn user within a certain period of time.In another embodiment, container can comprise detection means, and it is suitable for confirming capacity, remaining medicament quantity in the blister package for example, and when arriving at certain level, remind user.This will allow user to obtain new blister package within the scheduled time, and detection means can form a part that clamps device.In one embodiment, detection means is divided into two independently pick offs, and its record has the capacity of the bubble-cap of two row medicaments.In this embodiment, pick off for example can be confirmed medicament quantity and the position in each row in the two row medicaments.
Container can be suitable for holding more blister package, for example in compartment independently.
Container can comprise tears the edge, and the part of blister package can be torn along it.This can for example make single medicament or string medicament be more prone to from removing of blister package.For this reason, ejecting structure moves between the diverse location of being confirmed by the sense of touch indication.Through moving between two in these positions, the string medicament moves past this and tears the edge, and this row medicament can be torn thus.
In one embodiment, container is configured as can be erect on the table, and for example being similar to that photo frame has not bracket with foldable on overleaf or be similar to can unfolded books.Be similar among the embodiment that books equally open at container class, container open the visit that can write down user.
In one embodiment, container comprises the single operation button, can control various functions according to the operated number of times of button through it.As an example, single activates the visit that can indicate user, three activation in the certain hour; For example three times in 5s activate, and can indicate the data of user requirement about being obedient to, the activation of more times number; For example 5 times, can indicate the expectation of closing compliant structure.In this case, container can be with the conventional vessel that acts on the storage packing bubble-cap structure.
Preferably, ejecting structure is basic and the coplanar sheet form of housing.
In one embodiment; The lid device that is used at make position covering container opening is provided; This lid device can and be opened between the end position and to move in closed end position, open the said lid device of end position around the longitudinal axis rotation of container so that be formed for container is positioned at the support of the obliquity on the horizontal surface.Preferably, the lid device is actuated ejecting structure moving from the rest position to the ejected position from said closed end position to said at least a portion that moves of opening end position, and vice versa.These characteristics provide and have been easy to use, container powerful and attractive in appearance, and it has the inexpensive construction that is easy to make.
According to second aspect; The invention provides the container and the blister package of the compartment that is used for blister package; Said blister package forms the cavity that string at least has the multi-agent medicine; This is listed between first end and the second end and extends, and the clamping device cooperation that it is characterized in that at least one said end and adjacent cavity and ejecting structure makes said blister package moved into or shift out said container and is more prone to.In one embodiment, blister package comprises many weakened line, and it makes separately being more prone to of blister package between each cavity, thus can the tear used part of blister package of user when taking medicament away.In this embodiment, between at least one end and adjacent cavity, weakened line is not provided.This makes user all of a sudden blister package not to be shifted out in this end, and this end can be used for engaging with the clamping device of container thus.
Description of drawings
Below with reference to accompanying drawing the preferred embodiments of the present invention are described in more details, in the accompanying drawings:
Fig. 1 shows three different views according to first embodiment of container of the present invention;
Fig. 2 shows the variant of the container of the Fig. 1 with shelf support;
Fig. 3 shows the logical flow chart of the container of Fig. 1;
Fig. 4 shows another variant of the container of Fig. 1, and wherein second compartment is opened;
Fig. 5 shows the groove of first and second compartments of the container that gets into Fig. 1;
Fig. 6 shows the another variant of container shown in Figure 1, has to be used for the string medicament from the isolating edge of tearing of the blister package of container;
Fig. 7 to 9 shows three different views according to a second embodiment of the present invention;
Figure 10 shows the partial section of the embodiment of Fig. 7 to 9; And
Figure 10 a shows the details of Figure 10.
The specific embodiment
Fig. 1,2 with 4-6 show first embodiment according to container 1 of the present invention.
As shown in Figure 1, the container 1 of first embodiment comprises first groove 2 of the opening that forms first compartment and second groove 3 of the opening that forms second compartment.First compartment is used to store first blister package, and second compartment is used to store second blister package.First blister package is effective blister package, be consumed from this blister package medicine, and second blister package is " subsequent use " blister package that this second blister package can move to first compartment when the blister package in first compartment uses up.Container comprises housing 4, is used for for example visiting through the acoustical signal indication to user the device of the suitable time of blister package, is used to keep the immobilising device 5 of this blister package and is used for detecting the device of user to the visit of the blister package of compartment.
Make bubble-cap insert and extract first compartment out through ejecting structure (ejection structure) and be more prone to that this ejecting structure is by handle 6 operations, this handle 6 can slidably reciprocate on the outer surface of container and move the bubble-cap entering thus and shift out compartment.This exit structure can be shifted to open position and make position, and this open position is used for first compartment is outwards shifted out in encapsulation, and this make position is used for encapsulation is inwardly moved into first compartment.When user moved ejecting structure, this moving recording was (registered as) user visit this blister package in first compartment.Ejecting structure is connected to housing via linear guides, and this linear guides provides the linear slide of ejecting structure with respect to housing.
Container comprises the single press button (single compliance push button switch) 7 of being obedient to, and can activate particular functionality according to the activation number of times of switch in the predetermined time cycle through this switch user.
Container comprises signal transmitter spare 8, the optical signal of its conveyer belt color, and wherein color is indicated the compliance of user, and promptly user is observed the drug rehabilitation program how many times between given period.In addition, container comprises conveyer, is used to transmit acoustical signal, and it indicates when user is taken the potion medicine in the blister package.In the present embodiment; Container is transformed into attention state (attentive state) when user shifts out ejecting structure make position and turns back to make position from non-attention state; Be that blister package turns back to first compartment after taking out medicament; This container from attention state be converted back to non-attention state and for during this period compliance by record, medicament is taken according to drug rehabilitation program in this period.
In order to support correct Drug therapy, the following function that container has timer and carried out by the processing apparatus in the container:
In case user visit blister package was reset by the time of timer counting after writing down.In practice, this record is through moving ejecting structure to open position and turn back to make position or be obedient to button 7 through the user activation and realize.
After some cycles, for example when one day potion medicine of drug rehabilitation program regulation after 24 hours, warning is transmitted.
Snooze (snooze function), if first warning 15 minutes with 30 minutes afterwards medicament also do not taken away.
Reminder alerting, if after first warning in 6 hours medicament do not taken away.
Reminder alerting, if after first warning in 12 hours medicament do not taken away.
If medicament was not taken away within 24 hours+12 hours, counting is set to " shortage is obedient to ".
In addition, container definite interaction of being suitable for being described below is obedient to:
" adhere to (adherence) " and be defined as the summation of being obedient to (compliance) and lasting (persistence);
" being obedient to " is to take medicine away according to drug rehabilitation program, for example once a day.
" lastingly " is during whole therapeutic scheme (treatment regiment), to continue treatment.
" be obedient to the time " and be defined as 24 hours and add the reminder time (24+12=36 hour altogether) that is 12 hours to the maximum.The time of being obedient to always begins when resetting this device (between elementary period by user be provided with) from default time." default time " is defined as user and is obedient to button is set to warn the time greater than 5s time through pressing." be obedient to time range "=" being obedient to the time "-6 are hour to " being obedient to the time "+12 hour.
The example of warning time (under the worst situation first warning after 4 reminder alertings)
| First day XX:XX | Default time+ |
|
| Second day XX:XX | (as an example) do not taken out in |
|
| Second day, greedy sleeping XX:XX+15 minute | (as an example) do not taken out in |
|
| Second day, greedy sleeping XX:XX+30 minute | (as an example) do not taken out in |
|
| Second day XX:XX+12 hour | Warning 2-do not take out: be not obedient to-take out: be obedient to | |
| The 3rd day XX: | Warning | 2. is in first warning of default time |
| Or the like |
This device transmits the compliance of user according to algorithm as follows.7 days moving average of compliance algorithm computation.When restarting or reset, compliance should begin from the whole 7 days compliance the record to calculate.The instance of face as follows.Following numeral is being obedient to the tablet summation that time durations is taken away.
The past seven days (if restart/reset then all be obedient to calculating in 7 days) according to imagination:
Be obedient to very much in 5-7 days (green)
Noted being obedient in 3-4 days (orange)
Lacked in 0-2 days and be obedient to (redness)
Be obedient to the instance of work function
1=takes out tablet in being obedient to window (compliance window)
0=does not take out tablet in being obedient to window
The R=rebooting device
* algorithm all was obedient to beginning with past 7 days
Signal transmitter spare 8 comprises light emitting diode (LED).This LED illuminates the prism of shape with expression drug type, wherein drug rehabilitation program in compliant structure by sequencing to be used for this medicine.In the present embodiment, this shape indicates Caulis et Folium Oryzae, and it is irritated that it points to grass.Three kinds of color codes can be used to make the compliance signalling: green, orange and red.Green expression " being obedient to very much ", orange device " attention is obedient to " and red device " shortage is obedient to ".
It is 65dB is measured as 74dB apart from 8 feet places of this device sound level that the conveyer that is used to transmit sound is suitable for being transmitted in background.Warning is activated in 30s or the action advised is performed.
Can use following warning/sound:
| Warning | Sound is described | Note | |
| Warning/ |
XX | " default time setting ", the buzzer of two weak points in 0 to | |
| Warning | |||
| 2 | XX-XX-XX-XX-XX- | " taking-up medicament " | |
| Warning 3 | XXX-XXX-XXX-XXX | " blister package is back in the compartment " | |
| |
XX---XX---XX---XX--- | " by being obedient to button " |
This container is suitable for based on battery 9 operations.
This container is fabricated to the blister package 10 of the medicament that is used to comprise two hurdle tablet form especially.Each hurdle forms the row with 5 medicaments, and between each row, this blister package comprises weakened line 13, and these row can be torn from the remainder of blister package at this place.
Clamp mechanism comprises the front part and back member (invisible at Fig. 1) on the opposite side that is arranged in blister package 10.Front part comprises two elements 14,15, and one of them comprises arcuate part, and this arcuate part promptly partly centers on the part of the last string in the hurdle partly around the ledge of blister package.
Fig. 2 shows the variant according to the container of the first embodiment of the present invention, and wherein this container has shelf support 16, and it can be connected to the back surface of container and allow container upright on the table.
Fig. 3 shows logical flow chart.
Fig. 4 shows another variant according to the container of this first embodiment, and its middle cover 17 is hinged to housing 4 and makes can open in the compartment fully, is second compartment in this case.
Fig. 5 shows the groove 2,3 that gets into first and second compartments.First groove comprises first and second enlarged openings 18,19 and mid portion 20.This groove is the shape of the blister package 10 of disclosed type in the match map 1 thus, promptly has two row medicaments, for example tablet or pill.
Fig. 6 shows the another variant according to the container of first embodiment, wherein has to be used for string medicament 22 from the isolating edge of tearing of the blister package of container.In this variant; Be used for moving exit structure also thus with blister package shift-in and the handle 23 that shifts out compartment; 24 are provided with the sense of touch indication of position; Medicament under this position in the blister package is in respect to tear the tram at edge 21, and for example the weakened line of blister package is positioned at and tears near the edge.
Fig. 7 shows second embodiment according to container of the present invention to 10a.Similar reference number represent to have with Fig. 1 to 6 in the similar element or the parts of identical function among the embodiment.
This container 1 comprises housing 4, and it can comprise unshowned indicating device in the front side shown in its Fig. 7, such as LED or LCD and/or such as the compliant structure of describing hereinbefore, for example button form or the like.Housing 4 is flaky material such as the plastic form that are bent with the compartment that is formed for blister package 10.Ejecting structure with the form that ejects sheet 30 is accommodated in housing 4 inside in the closed end position of container as shown in Figure 71.In centre position shown in Figure 8 and Fig. 9, open end position, eject sheet 30 and eject with side outstanding from housing 4 from housing 4.Figure 10 shows at the ejection sheet 30 corresponding to the ejected position of Fig. 8 and 9, and the details of the ejection sheet 30 among Figure 10 has been shown among Figure 10 a.
Eject the immobilising device that sheet 30 also comprises insert (insert) 33 forms, be used for blister package 10 is fastened to ejection sheet 30.Shown in Figure 10 a, insert 33 comprises two convexities, and it can keep the blister package 10 of shown in Figure 10 a arrow, inserting, i.e. the lamellar of blister package 10 partly is pushed into fastening or fixed position.In the fastening or fixed position of blister package, convexity is pressed to each other in the plate portion both sides of blister package 10.Two blister packages are maintained in the insert 33 in the variant of the unshowned second embodiment of the present invention, and for example second blister package is maintained between in the convexity of insert one and the 3rd protrusion.
Ejecting the dorsal part 30c of sheet 30 can be alternatively or additionally comprise the immobilising device (not shown) of other cellular type, its corresponding to the tablet projections 10a of blister package 10 so that blister package 10 better connection on ejection sheet 30 is provided.Comprise in blister package 10 under the situation of ten tablet projections that dorsal part will comprise ten holes of correspondingly locating and being shaped.In this variant, these crownings are to the dorsal part 30c that ejects sheet 30, yet they also can be in the opposite direction in other embodiments.In another unshowned variant, the hole is set on the coplanar individual sheets of dorsal part 30c of orientating and eject sheet 30 as.
In the unshowned variant of the second embodiment of the present invention, ejecting structure does not comprise front side 30b and dorsal part 30c.In this variant, insert 33 self is released housing with blister package 10 in pop-up action.Yet, shown in variant be preferably because front side 30b and dorsal part 30c provide the support to blister package 10.
Being used for detecting the user can be for example to be arranged on insert 33 or at the pick off of protruding 32 end to the device of the visit of container 1.
When expectation is opened container 1 so that when obtaining tablet, user will cover the centre position that 34 closed end position from Fig. 7 move to Fig. 8.This can make their separated from one another realizations through using a hand grip housing 4 another hand grip lid 34 and pullling them.This provides and has covered 34 linear slide, this through minor axis will eject sheet 30 pull out housing 4 openings lateral edges and away from its rest position in housing 4.Housing 4 be formed make when lid 34 when ejecting sheet 30 and get into the centre position of container 1 of Fig. 8, lid 34 discharges and the longitudinal axis that can wind the container 1 that is limited semiaxis rotates from linear slide rail.So user rotates to second end position as shown in Figure 9 with lid.Can easily visit blister package 10 now.User takes out blister package 10, tears or releases tablet and again blister package 10 is inserted into insert 33.For closed container 1, user is carried out reverse operating, for example takes container 1 to closed end position from opening end position.
Opening in the end position in Fig. 9, the lid 34 of rotation are formed for container 1 is positioned at the support such as the obliquity on the such horizontal surface (not shown) of desktop.Container 1 preferably includes spring device (not shown) or other appropriate device well known by persons skilled in the art are used for lid 34 is remained on position of rotation shown in Figure 9, can not collapse in the time of for example on being positioned at said horizontal plane.
In the variant of the second embodiment of the present invention, the spring device that other can be provided to be being used for ejection sheet 30 to the ejected position biasing, and such spring device is for example actuated through button etc.
Claims (27)
1. be used for the container (1) of blister package, this container comprises:
Housing (4), this housing is formed for the compartment of said blister package,
Be used for to the device of suitable time of the said blister package of user indication visit and
Be used for detecting the device of user to the visit of the blister package of said compartment,
It is characterized in that said container also comprises ejecting structure; Wherein this blister package is fixed to this ejecting structure; This ejecting structure (6) can be shifted to and be used for packing is outwards shifted out the open position of said compartment, and can shift to the make position that is used for packing is inwardly moved into said compartment
Wherein, i) said blister package (10) can be fixed to said ejecting structure through clamping device, and this clamping device comprises two parts that form groove, promptly back member and adjacent front part, and wherein said blister package (10) is inserted in this groove;
Ii) said container (1) also comprises handle (6), is used to operate said ejecting structure, and wherein this handle (6) can slidably reciprocate on the outer surface of said container (1) thus and to move said blister package (10) and get into and shift out compartment; And
Iii) said back member and front part can along close to each other and away from direction relative to each other mobile.
2. container as claimed in claim 1 wherein detects the visit of user to the blister package in the said compartment through detecting said ejecting structure with respect to moving of said housing.
3. according to claim 1 or claim 2 container, wherein said ejecting structure is connected to said housing via linear slide rail, and wherein this linear slide rail allows said ejecting structure to move with respect to said housing is linear.
4. according to claim 1 or claim 2 container, wherein said ejecting structure is prevented from from the separation of said housing.
5. according to claim 1 or claim 2 container also comprises the detection means of the existence that can detect the blister package that is fixed to said ejecting structure.
6. container as claimed in claim 1 also comprises being suitable for indicating the last compliant structure of visiting the time of the blister package in the said compartment of user.
7. container as claimed in claim 6, wherein said compliant structure are suitable for being transformed into non-attention state according to receiving user Visitor Logs signal from attention state.
8. container as claimed in claim 7, wherein said user Visitor Logs signal provides through moving of said ejecting structure.
9. container as claimed in claim 8, wherein said user Visitor Logs signal only provides through moving of ejecting structure when said compliant structure is in attention state.
10. container as claimed in claim 7, wherein said user Visitor Logs signal provides through the activation of button.
11. container as claimed in claim 10, the activation through button under the situation of the state of not considering said compliant structure of wherein said user Visitor Logs signal provides.
12., also comprise being suitable for making said compliant structure being in said non-attention state is transformed into said attention state from said non-attention state after the scheduled time timer like the described container of claim 7-11.
13. container as claimed in claim 12 also comprises being used for the indicating device that according to the said compliant structure conversion from non-attention state to attention state transmits notification signal.
14. container as claimed in claim 13, wherein said indicating device transmits notice with predetermined period at said compliant structure after non-attention state is transformed into attention state.
15. like each described container among the claim 7-11, wherein said compliant structure is suitable for after being in the attention state predetermined period, not receiving under the situation of said tracer signal and is transformed into non-attention state.
16. container according to claim 1 or claim 2 also comprises the processing apparatus that is suitable for confirming to be obedient to level, this expectation of being obedient to horizontal indicator substance consumes frequency and receives poor between the frequency of said tracer signal.
17. container as claimed in claim 16; Wherein for a plurality of intervals; Wherein in each interval, infer user and visit said blister package at least once; Said processing apparatus is suitable for each interval write down when this receives said tracer signal at interval is obedient to expression, and record lacks and is obedient to expression when not receiving tracer signal at this interval.
18. container as claimed in claim 17, wherein said processing apparatus are suitable for confirming hierarchy level based on being obedient to expression and lacking the quantity of being obedient to expression in the interval in succession of predetermined quantity.
19. container as claimed in claim 18, wherein said processing apparatus comprises light emitting diode, and it is set to transmit has coloured light, and from a plurality of colors, selects color based on said hierarchy level.
20. container as claimed in claim 19, wherein said container also comprises protecgulum, and said light emitting diode is set to the transverse conveyor chrominance signal in prism, and this prism forms the part of the protecgulum of said container.
21. container as claimed in claim 20, wherein said prism have the shape of the material in the sign blister package.
22. container according to claim 1 or claim 2 also comprises being suitable for confirming that said ejecting structure is not positioned at the timer of the period of make position.
23. container as claimed in claim 22, wherein said compliant structure only are suitable for timer is confirmed situation that ejecting structure is not in the close position in the interval greater than predetermined time interval under, being transformed into non-attention state from attention state.
24. container as claimed in claim 1, at least one in wherein said back member and the front part comprises clamping structure, and it is suitable at least in part the ledge around blister package.
25. container according to claim 1 or claim 2 also comprises the additional compartment that is used for extra bubble-cap clamp.
26. container as claimed in claim 1; Wherein also comprise blister package; This vessel is useful on the compartment of blister package, and said blister package forms the cavity that string at least has the multi-agent medicine, and this is listed between first end and the second end and extends; It is characterized in that the clamping device cooperation of at least one said end and adjacent cavity and ejecting structure, this ejecting structure is suitable for said blister package is moved into or shift out said container.
27. container as claimed in claim 26, wherein said blister package comprises many weakened line, and it makes separately being more prone to of blister package between each cavity, thus can the tear used part of said blister package of user when taking medicament away.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75962106P | 2006-01-18 | 2006-01-18 | |
| DKPA200600079 | 2006-01-18 | ||
| DKPA200600079 | 2006-01-18 | ||
| US60/759,621 | 2006-01-18 | ||
| PCT/DK2007/050003 WO2007082543A1 (en) | 2006-01-18 | 2007-01-18 | A container for a blister package |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101384237A CN101384237A (en) | 2009-03-11 |
| CN101384237B true CN101384237B (en) | 2012-08-22 |
Family
ID=36917273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2007800059446A Expired - Fee Related CN101384237B (en) | 2006-01-18 | 2007-01-18 | A container for a blister package |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20100236973A1 (en) |
| EP (1) | EP1973512B1 (en) |
| CN (1) | CN101384237B (en) |
| CA (1) | CA2637212A1 (en) |
| HK (1) | HK1126955A1 (en) |
| WO (1) | WO2007082543A1 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11565034B2 (en) | 2017-02-24 | 2023-01-31 | Sanofi | Packaging assembly |
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| WO2009000890A2 (en) * | 2007-06-27 | 2008-12-31 | N.V. Organon | Medication container |
| US7607538B2 (en) * | 2007-08-27 | 2009-10-27 | Schering-Plough Healthcare Products, Inc. | Container for transporting a blister package |
| US8061513B2 (en) * | 2008-08-21 | 2011-11-22 | Very Special Hearts, LLC | USB flash drive with integrated medication holder |
| WO2015021014A1 (en) * | 2013-08-06 | 2015-02-12 | Meadwestvaco Corporation | Smart dispensing packaging system |
| GB2549688B (en) * | 2015-02-27 | 2019-04-24 | Westrock Mwv Llc | Packages with monitoring devices |
| JP6876695B2 (en) | 2015-11-30 | 2021-05-26 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Packaging assembly |
| WO2017093199A1 (en) | 2015-11-30 | 2017-06-08 | Sanofi-Aventis Deutschland Gmbh | Packaging assembly with mounting attachment |
| DK3884973T3 (en) | 2017-02-24 | 2023-02-27 | Sanofi Sa | PACKAGING UNIT FOR INJECTION UNITS |
| USD841805S1 (en) | 2017-10-04 | 2019-02-26 | West Pharmaceutical Services, Inc. | Container lid |
| USD841158S1 (en) | 2017-10-04 | 2019-02-19 | West Pharmaceutical Services, Inc. | Container lid |
| USD841157S1 (en) | 2017-10-04 | 2019-02-19 | West Pharmaceutical Services, Inc. | Container and lid |
| US10842300B2 (en) * | 2018-04-19 | 2020-11-24 | Carl Reid | Mountable container |
| DE102019133076A1 (en) * | 2019-12-04 | 2021-06-10 | Aesculap Ag | Composite packaging for easier aseptic presentation of medical products |
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Also Published As
| Publication number | Publication date |
|---|---|
| US20130008818A1 (en) | 2013-01-10 |
| WO2007082543A1 (en) | 2007-07-26 |
| CA2637212A1 (en) | 2007-07-26 |
| US20100236973A1 (en) | 2010-09-23 |
| EP1973512A1 (en) | 2008-10-01 |
| CN101384237A (en) | 2009-03-11 |
| HK1126955A1 (en) | 2009-09-18 |
| EP1973512B1 (en) | 2012-10-17 |
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