CN101380316A - Multifunctional external antibiotic preparation and production method thereof - Google Patents
Multifunctional external antibiotic preparation and production method thereof Download PDFInfo
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- CN101380316A CN101380316A CNA2007101393417A CN200710139341A CN101380316A CN 101380316 A CN101380316 A CN 101380316A CN A2007101393417 A CNA2007101393417 A CN A2007101393417A CN 200710139341 A CN200710139341 A CN 200710139341A CN 101380316 A CN101380316 A CN 101380316A
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- antibiotic preparation
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Abstract
The invention relates to a multifunctional antibacterial pharmaceutical composite for external use. The composite is a solution medicament composed of benzalkonium bromide, benzalkonium chloride, quaternary silyl ammonium salt, ethanol and deionized water. By spraying and other ways, the composite can quickly cure the diseases such as cutaneous superficial fungal infections of tinea on manus and pedis, tinea corporis and the like, pyogenic dermatosis, wound infection of cutaneous trauma, cutaneous infection due to burn and scald, and the like; after the composite is sprayed once, various articles contacting with the skin can have antibacterial and deodorizing functions for a long time, therefore, the articles which are easy to store bacteria become a long-term antibacterial barrier. The composite is an ideal medicament for both preventing and treating skin diseases.
Description
Technical field
The present invention relates to medicine and disinfectant or antibiotic hygiene article sector, particularly a kind of multifunctional external antibiotic preparation compositions and manufacture method thereof.
Background technology
Pathogenic microorganism at every moment can threaten or damages human body skin or article.Therefore to study fine antimicrobial products, killing pathogenic bacteria, the protection health also can make other animal or article avoid the pathogenic bacteria infringement.
The present invention is improvement and the raising to the Chinese invention patent ZL01133466.5 that is developed by the present patent application people.ZL01133466.5 patent of invention by the present patent application people development, because when development is in order to make this product solubility good, must use a large amount of ethanol (〉=80%V/V just solubilized a little, and extremely unstable), using like this has several shortcomings: 1, can cause certain stimulation or pain to skin or wound.2, inflammable.3, cost height.4, through long-term observation, difficult quality control.
Test for many years through us,, mix, irreversible precipitation can take place at once just antibacterial benzalkonium bromide and long-lasting antiseptic deodorant agent organosilicon quaternary ammonium salt are difficult in together if do not use high concentration ethanol, or the adherent phenomenon of solids content.
But benzalkonium bromide has good penetration, can kill promptly the deep skin pathogenic bacteria and pull the grass up by its roots, beneficial to the treatment tinea pedis especially, so must use, through groping for many years, we have developed the use micro ethanol finally, and to skin or the faint Multifunction external antibiotic preparation of wound zest.
The object of the invention
The purpose of this invention is to provide a kind of antimicrobial agent compositions that contains small amount of ethanol, shallow fungal infection such as it not only can the rapid healing tinea manus and pedis, tinea corporis, and to multiple by bacterial suppurative dermatosis, trauma wounds infect and the skin burn postoperative infection to prevent and treat curative effect very good.Can also make the effect of multiple article maintenance long-lasting antiseptic deodorants such as the glove that often contacts with brothers and health, footgear, underwear, wound dressing.This just makes and originally conceals the multiple article of pathogenic bacteria easily, is transformed into and can resists the barrier of extraneous germina infection, thereby make people's health from then on no longer be subjected to the puzzlement of tinea and other suppurative dermatosis.And, after using this chemicals treatment, no longer include brackish foreign odor flavor for a long time with the article of contact skin.Also having most important benefit is exactly to use ethanol less, thereby chafe or cause wound pain no longer reduces the cost.
Technical scheme of the present invention
Technical scheme of the present invention is a kind of quick-acting and long lasting again sterilized pharmaceutics of preparation, this medicament is SOLUTION PROPERTIES, employing is sprayed, floods or the mode of smearing makes this medicament reach the sufferer place, and with the sufferer place often contact such as article such as glove, footgear, underwear, wound dressings, thereby play shallow fungus type dermatosiss such as fast long-acting control tinea manus and pedis, tinea corporis; And the multiple infection of dying, causing behind the skin burn by bacterial suppurative dermatosis, skin injury mouthfeel of control etc.
A kind of multifunctional external antibiotic preparation of the present invention is characterized in that: described antimicrobial agent comprises following component by weight percentage:
A, antibacterial: benzalkonium bromide, content is: 0.1-2%,
B, antibacterial: benzalkonium chloride, content is: 0.1-2%,
C, long-lasting antiseptic deodorant agent: organosilicon quaternary ammonium salt, content is: 0.3-3%,
D, ethanol: content is 2.5-20%,
E, deionized water: content is 73-97%.
Manufacture method of the present invention is as follows:
After earlier benzalkonium chloride and organosilicon quaternary ammonium salt one being reinstated ethanol dilution, add mixing in the entry in the stirring, added the benzalkonium bromide mixing again after waiting about 10 minutes.
Make mixing of materials by above-mentioned weight percent concentration and method, can obtain a kind of multifunctional external antibiotic preparation compositions of good stability.
Advantage of the present invention
A kind of multifunctional external antibiotic preparation provided by the present invention is the time that the inventor goes through more than ten years, gropes repeatedly, by developing with great concentration and improvement forms.The inventor is by personal repetition test, the household, the test that friend and various age level (18-65 years old) are more than 60 person-time shows, effect is as follows: light, moderate tinea manus and pedis and tinea corporis are after using this product three to five times (once a day), and symptom can take a turn for the better, the skin lesion healing, skin recovers naturalness gradually, severe tinea pedis (ten toes all rotten to the corn) also can return to healthy skin gradually after using this product five to ten times, total effective rate absolutely.The effect that also can obtain rapid healing after this product is used in the infection that cause behind the skin wound pyogenic infection that is caused by wound, the skin burn etc.
Because the organosilicon quaternary ammonium salt among the present invention, can with the article surface of contact skin, can form firm chemical bond; wash for a long time to wear for a long time and do not come off,, form the protection barrier so can keep the antibacterial and deodouring function for a long time; long-actingly prevent that pathogenic bacteria from invading skin once more, cause dermatosis.The present invention other benefit, be exactly only to need use small amount of ethanol, saved great amount of cost, no longer chafe or wound, thus make the patient no longer feel pain unbearably.
Formulation Example of the present invention:
Benzalkonium bromide (bromogeramine) 0.25%
Benzalkonium chloride (geramine) 0.25%
Organosilicon quaternary ammonium salt 1%
Ethanol 6%
Excess water
Compound method be earlier with benzalkonium chloride and organosilicon quaternary ammonium salt with ethanol dilution after, add mixing in the entry in the stirring, add the benzalkonium bromide mixing again after about 10 minutes.
All compositions mix the back fill.
Claims (2)
1, a kind of multifunctional external antibiotic preparation is characterized in that: described antimicrobial agent comprises following component by weight percentage:
A, antibacterial: benzalkonium bromide, content is: 0.1-2%,
B, antibacterial: benzalkonium chloride, content is: 0.1-2%,
C, long-lasting antiseptic deodorant agent: organosilicon quaternary ammonium salt, content is: 0.3-3%,
D, ethanol: content is 2.5---20%,
E, deionized water: content is 73-97%.
2, according to the manufacture method of the described a kind of multifunctional external antibiotic preparation of claim 1, it is characterized in that:
After earlier benzalkonium chloride and organosilicon quaternary ammonium salt one being reinstated ethanol dilution, add mixing in the entry in the stirring, added the benzalkonium bromide mixing again after waiting about 10 minutes.
Make mixing of materials by above-mentioned weight percent concentration and method, can obtain a kind of multifunctional external antibiotic preparation compositions of good stability.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007101393417A CN101380316B (en) | 2007-09-05 | 2007-09-05 | Multifunctional external antibiotic preparation and production method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007101393417A CN101380316B (en) | 2007-09-05 | 2007-09-05 | Multifunctional external antibiotic preparation and production method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101380316A true CN101380316A (en) | 2009-03-11 |
| CN101380316B CN101380316B (en) | 2011-08-03 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2007101393417A Expired - Fee Related CN101380316B (en) | 2007-09-05 | 2007-09-05 | Multifunctional external antibiotic preparation and production method thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN101380316B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104652133A (en) * | 2015-02-15 | 2015-05-27 | 浙江兆新织造有限公司 | Anti-bacterial and odor-resistor anti-mite infant bedding fabric |
| CN107789209A (en) * | 2017-11-01 | 2018-03-13 | 上海展艺商贸有限公司 | Alkaline electrolyte water antimicrobial fluid and antibacterial wet tissue |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107412213B (en) * | 2017-06-30 | 2020-03-17 | 深圳市海文深生物科技有限公司 | Multifunctional external antibacterial and sterilizing agent and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1226034C (en) * | 2001-11-19 | 2005-11-09 | 陈唐龙 | Durably antibacterial and deodouring medicine for treating tinea manuum and tinea pedis |
-
2007
- 2007-09-05 CN CN2007101393417A patent/CN101380316B/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104652133A (en) * | 2015-02-15 | 2015-05-27 | 浙江兆新织造有限公司 | Anti-bacterial and odor-resistor anti-mite infant bedding fabric |
| CN107789209A (en) * | 2017-11-01 | 2018-03-13 | 上海展艺商贸有限公司 | Alkaline electrolyte water antimicrobial fluid and antibacterial wet tissue |
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| Publication number | Publication date |
|---|---|
| CN101380316B (en) | 2011-08-03 |
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Owner name: SHENZHEN ZHENGNENG QIANGDA TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: CHEN YANE Effective date: 20130904 |
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