CN101350923A - Method for communication and indication of interactive iatrology image - Google Patents

Method for communication and indication of interactive iatrology image Download PDF

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CN101350923A
CN101350923A CN 200810042429 CN200810042429A CN101350923A CN 101350923 A CN101350923 A CN 101350923A CN 200810042429 CN200810042429 CN 200810042429 CN 200810042429 A CN200810042429 A CN 200810042429A CN 101350923 A CN101350923 A CN 101350923A
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jpip
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server
resolution
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CN101350923B (en
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田媛
蔡伟华
孙健永
张建国
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Shanghai Institute of Technical Physics of CAS
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Shanghai Institute of Technical Physics of CAS
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Abstract

An interactive medical image communications and display method which is based on JPEG2000 compressed data package transmission; the method uses the superior performance of JPEG 2000 compressed algorithm, and with the method, the JPEG 2000 compression process is implemented on the medical image in the pattern based on subsections; in this way, only the partial data package corresponding to image windows which client terminal is interested in rather than the entire image data is transmitted under the client/server environment and the client terminal could extract and display the medical image interactively based on the image content according to requests. With the invention, high-resolution DICOM medical image can be transmitted and displayed in real time fast and efficiently through WAN even when the bandwidth is limited to realize fast share of medical image information between PACS systems in different areas and hospitals; with the invention, medical resource can be effectively utilized, and the medical treatment effect, quality and efficiency of clinic activities such as long-distance consultation can be promoted.

Description

A kind of interactive medical image communication and display packing
Technical field:
The present invention relates to information communication, computer image processing technology, be meant a kind of interactive medical image communication and display packing especially based on the transmission of JPEG2000 compressed data packets.
Background technology:
Along with the digitized realization of various medical informations, and being extensive use of of the Internet and correlation technique, Regional Synergetic medical treatment and bidirectionally transfering consultation are being carried out gradually and are being put into practice.Patient has been exceeded hospital's scope based on the medical diagnosis and treatment activity of digital medical information, need in certain zone, call patient's various medical informations between (or in group of hospital) how tame hospital mutually, thereby provide continuous, consistent collaborative medical services to patient, to improve medical treatment level, reduce possible malpractice, to reduce rechecking, alleviate the overlapping investment of hospitalize burden, actual bodily harm and minimizing hospital digitisation, improve the utilization ratio of medical resource.For setting up wide area network Regional Synergetic medical system, the current different PACS of hospital (the PictureArchiving and Communication System) system that progressively carrying out carries out integrated research, and patient's medical information (comprising image) can be had access to and extract from the PACS system of different hospitals.
Medical image data shared fast main bottleneck that exchanges between the PACS of different hospitals system of realizing patient is: medical image has high-resolution (〉=2000 * 2000, as CR, DR, Mammography etc.), big volume (〉=60~400MB, as MR, CT, US Series etc.) characteristics, and the message transmission rate of Wide Area Network is limited, therefore under the prerequisite that guarantees the medical diagnosis quality, these high-resolution medical images are carried out efficient quick transmission, demonstration and processing in real time be difficult to realize perfectly.The solution of at present more existing systems, mostly adopt the mode of transmitted image, the agreement consultation of doctors in advance to carry out as teleradiology on, consultation system, image needed to spend transmit in advance before the consultation of doctors in 4~24 hours, the limitation of this mode is the image that can not visit online, in real time in the long-range PACS system, and diagnostic procedure complexity, efficient are lower; " Chinese medical apparatus magazine " (2006 30 the 4th phases of volume, the 299-301 page or leaf) proposes a kind of employing JPEG2000 splicing block (Tiles) data transmission manner in " based on the wireless transmission and the demonstration of the high-resolution DICOM medical image of JPIP agreement " that magazine is delivered and visited the high-resolution medical image, this mode is owing to adopt the splicing block partitioned image, and to each splicing block independent compression coding, all splicing block data that in network, need the transmission client area-of-interest to be covered, data quantity transmitted is bigger, visit underaction to view data, efficient is not high, only can show the part image data in client.
Summary of the invention:
The object of the present invention is to provide a kind of interactive medical image communication and display system, solve on the network of limited bandwidth the high-resolution medical image is carried out efficiently, transmits fast, in real time and the technique for displaying problem based on the transmission of JPEG2000 compressed data packets.
The present invention makes full use of the good characteristic of JPEG2000 compression algorithm, the medical image employing is carried out the JPEG2000 compression based on the mode of subregion (Precincts-based), the pairing partial data bag of the interested image window of a transmission client (Packets) under client/server environment, and needn't transmit whole image data, client can be extracted and the display of medical image by the demand interactively, compared with the prior art, the present invention is more meticulous and flexible to the visit granularity of image, data quantity transmitted still less in network, between the network of limited bandwidth, can transmit and the display of high resolution medical image more efficient and apace, thereby promote the structure of Regional Synergetic medical system, improve the medical treatment level of clinical events such as remote medical consultation with specialists, quality and efficient.
Technical scheme of the present invention is as follows:
The present invention adopts based on the mode of subregion medical image is carried out JPEG2000 compression processing, image is not carried out the preliminary treatment that splicing block is cut apart, entire image is compressed as a splicing block, wavelet sub-band to each stage resolution ratio of each picture content adopts subregion to divide, partition size on each stage resolution ratio is identical, and a subregion comprises three encoding blocks and is beneficial to obtain high space access fineness.Comprise code stream principal mark head and a splicing block data division in the gained image compression code stream, this splicing block data division comprises a series of packet.Server is according to interested window (the Window Of Interest of client to image, be called for short WOI, be meant interested area of space, resolution levels, component and quality layers) relevant packet in client transmissions target image compressed bit stream, the step of the access images of client terminal interactive comprises:
(1) low-resolution image preview: client sends request according to the resolution levels of required image to server, and server extracts the response package client relevant with the resolution levels of client-requested according to request from the targeted compression image code stream.Client receives data, and reorganization JPEG2000 code stream and decompress(ion) show low-resolution image.
(2) high-resolution of area-of-interest shows: after the low-definition version of image had been arranged, client sent the high-resolution request of area-of-interest to server according to user's area-of-interest (as the focus zone).Server extracts from the targeted compression image code stream and the corresponding packet of request, generates response message and returns to client.Client receives data, and reorganization JPEG2000 code stream and decompress(ion) show the high-definition picture of area-of-interest.
A kind of interactive medical image communication and display system based on the transmission of JPEG2000 compressed data packets that the present invention proposes, its system comprise PACS server, a coupled JPIP server and a plurality of JPIP client three parts.Adopt high-speed local area network to connect between PACS server and the JPIP server, available slow wan between JPIP server and a plurality of JPIP client (as Internet, GPRS and 3G etc.) is connected.
A kind of interactive medical image communication and display system that the present invention proposes based on the transmission of JPEG2000 compressed data packets, its system works flow process is as follows: the JPIP client generates the JPIP request according to the user to the window interested of image and sends to the JPIP server; After receiving the request of client, the JPIP server is according to the unique identifier of requested image, download this image to this locality by WADO communication protocol (or other is based on tcp/ip communication agreement) from the PACS server, this image is carried out compressing based on the JPEG2000 of subregion, and, generate JPIP message response JPIP client according to JPIP request corresponding packet of extraction from the image compression code stream; After the JPIP client receives JPIP response message from the JPIP server, resolve JPIP message, the mode that adopts empty bag the to fill small echo high-frequency sub-band subregion JPEG2000 code stream of recombinating, the decompress(ion) bit stream data also shows.
The JPIP server adopts data base administration and memory management technology, before response JPIP client, to be saved in local data base from the DICOM image that the PACS server is downloaded, the image employing is carried out the JPEG2000 compression based on the compress mode of subregion, then the compressed image code stream is loaded in the internal memory, the JPIP response message of regeneration JPP-stream type returns to the JPIP client, when the JPIP client is asked same width of cloth view data once more, the JPIP server can directly read the compressed bit stream data of this image from internal memory, thereby improved response speed greatly, each image object all has a lifetime (time that the last access time is experienced till now) in internal memory, when the lifetime exceeds a certain given limit, this image object will be deleted from internal memory, thereby effectively uses internal memory; The bit stream data that receives from the JPIP server before the JPIP customer end adopted buffer stores, comprise DICOM header, code stream master head, splicing block head and packet, wherein each packet is by these four parameter identifications of resolution, quality layers, component and subregion, when drawing image, from buffering area, extract required bit stream data, when JPIP client once more during the requested image data, to in the JPIP request, comprise the buffer models field, be used for describing the bit stream data that received from the JPIP server last time; The JPIP server is all safeguarded a buffer models for each session, be used for describing the buffer state of JPIP client, when comprising the buffer models field in the received JPIP request, upgrade the buffer models of this session earlier with the buffer models field value, send response message again, for existing bit stream data in the JPIP client buffer district, the JPIP server can not repeat transmission, thereby has avoided the transmission of redundant data in the network; When the JPIP client is rebuild the JPEG2000 code stream, adopt the sky of a series of distance of zero mark degree to wrap the subregion outside the area-of-interest in the high-frequency sub-band of filling on each resolution levels, when display image, show area-of-interest with full resolution, with the image-region outside the low resolution demonstration area-of-interest, thereby can provide the contextual information of area-of-interest in image.
System of the present invention has standardization and opening.It can be applied in the third party PACS system of any support based on the image querying service of DICOMWADO agreement (or other is based on tcp/ip communication agreement).
JPIP client in the system of the present invention can be integrated into the diagnostic work station, the Internet that connects by low speed visits the high-resolution medical image in the long-range PACS system, also can be applied to the radio hand-held equipment (as wireless PDA etc.) of resource-constrained, by wireless network (as WLAN, GPRS or 3G etc.) visit high-resolution medical image.
Effect of the present invention:
The present invention has made full use of the random access characteristic of JPEG2000 bit stream data bag, the high compression rate of JPEG2000 compression algorithm and resolution flexible, in network, only need a spot of data of transmission can satisfy the diagnosis requirement of doctor to image, as a width of cloth original size is the CR image of 9.76MB, resolution is 2048 * 2500, size is 5.18MB after the JPEG2000 lossless compress, ask the low-definition version of this image 256 * 313, in network, only need transmission 113KB, data volume only is 2.13% of a whole compressed image, ask the area-of-interest of 512 * 512 sizes of this image full resolution, only need transmission 362KB in network, data volume only is 6.82% of a whole compressed image.
Description of drawings:
Fig. 1 is interactive medical image communication and the display system architectures figure based on the transmission of JPEG2000 compressed data packets of the present invention.
Fig. 2 be the invention process example based on the interactive medical image communication of JPEG2000 compressed data packets transmission and the software configuration and the data flow sketch of display system.
Fig. 3 is the workflow diagram based on the JPIP server of the interactive medical image communication of JPEG2000 compressed data packets transmission and display system of the invention process example.
Fig. 4 is the workflow diagram based on the JPIP client of the interactive medical image communication of JPEG2000 compressed data packets transmission and display system of the invention process example
Embodiment:
Provide a better embodiment of the present invention below in conjunction with Fig. 1-Fig. 4, further the present invention is elaborated, enable to be easier to understand architectural feature of the present invention and functional characteristics.
Interactive medical image communication and display system based on the transmission of JPEG2000 compressed data packets of the present invention, its system comprises the PACS server, coupled a JPIP server and a plurality of JPIP client three parts, its structure chart is as shown in Figure 1.The PACS server is connected by high-speed local area network with the JPIP server, and communicates by WADO agreement (or other is based on tcp/ip communication agreement); The JPIP server is connected with the wide area network of a plurality of JPIP clients by limited bandwidth, and communicates by the JPIP agreement.Said a plurality of JPIP client can be the PACS display workstation, also can be wireless PDA.
In the present embodiment DICOM image being carried out the partition size that JPEG2000 compression adopts is 32 * 32; The PACS server adopts Web Service to realize DICOM WADO (or other is based on tcp/ip communication agreement) image querying service in the present embodiment, and the JPIP server is by calling the Web service query image of PACS server; Present embodiment is implemented in the JPIP agreement on the http protocol, and the JPIP client is embedded into the JPIP request in the HTTP GET request, and the JPIP server is included in the JPIP response message in the http response message body; Present embodiment adopts the SSL technology that the data of transmitting between JPIP server and the JPIP client are encrypted, with the medical data that guarantees patient in the wide area network safety of transmission.
The each several part composition is described below respectively:
The JPIP of first server:
The JPIP server of present embodiment connects PACS server and a plurality of long-range JPIP client as network middleware, the JPIP server receives the query requests based on picture material from the JPIP client, extracts image and extract corresponding bag data from the image compression code stream from the PACS server lookup to send it back the JPIP client.The JPIP server adopts database and memory management technology to improve the response performance of JPIP server, adopts buffer models and session management mechanism management and storage package data, to reduce the volume of transmitted data in the network.
Present embodiment based on the interactive medical image communication of JPEG2000 compressed data packets transmission and its software configuration sketch of display system as shown in Figure 2.The JPIP server is by forming with lower module: JPIP module, JPEG2000 code stream module, database management module, memory management module, image format conversion module, image querying module, image receiver module, network function module, log pattern and local resource administration module.Wherein the function of JPIP module comprises the JPIP request of resolving client and generates the JPIP response message; The function of JPEG2000 code stream module comprises parsing JPEG2000 image compression code stream and extracts with JPIP from JPEG2000 image compression code stream and ask corresponding bit stream data bag; Database management module is responsible for the insertion and the inquiry of image information; The function of memory management module comprises image object management, session management and buffer model management; The image format conversion module carries out compressing based on the JPEG2000 of subregion to the DICOM image that is received by the image receiver module; The image querying module is extracted image according to the unique identifier of requested image from the PACS server lookup; The image receiver module receives the DICOM image that is returned by the PACS server and is saved in local hard drive according to WADO/HTTP agreement (or other is based on tcp/ip communication agreement); Network function module is responsible for monitoring the request of JPIP client, if there is client to connect, then starts the request of a thread process client, and the JPIP response message that the JPIP module is generated sends to client, and the The data SSL technology of transmission is encrypted; Log pattern register system security log and error log; The local resource administration module is made regular check on the operating position of local hard drive, if the hard drive space utilization rate is too high, then the image of storing in the hard disk is cleared up.
The workflow of the JPIP server of present embodiment is as follows:
The JPIP server of present embodiment comprises JPIP service processes and local resource managing process.The workflow of JPIP service processes is as shown in Figure 3: step 10, and service starts; Step 11 is monitored the connection request of JPIP client, if receive the connection request of client, then execution in step 12, otherwise circulation is monitored; Step 12, when the connection request that receives client, starting a new thread process should ask; Step 13, the JPIP that resolves client asks; Step 14, the image object of search request in internal memory, the Session ID field in the search request in internal memory at first, if the image object that then obtains this Session ID correspondence is arranged, execution in step 111, otherwise be that this JPIP client is distributed a new Session ID, and whether the image object of search request exists in internal memory, if exist then execution in step 111, if there is no execution in step 15 then; Step 15, the image of search request in local data base, if image exists in local data base, then execution in step 19, otherwise execution in step 16; Step 16, the Web image querying service of calling the PACS server, the image of download request; Step 17 carries out handling based on the JPEG2000 compression of subregion to the DICOM image of downloading from the PACS server; Step 18 is stored in image information in the local data base; Step 19 is loaded into DICOM header and compressed image code stream the internal memory from hard disk; Step 110 is resolved the JPEG2000 compressed bit stream that is loaded into by step 19 in the internal memory, obtains the information of each bag in JPEG2000 compression parameters and the code stream; Step 111 is upgraded buffer model, if comprise the buffer models field in the request, then upgrades the buffer model of current sessions with this field value; Step 112 is extracted with JPIP from the compressed bit stream of image object and is asked corresponding packet; Step 113, the packet that extracts according to step 112 generates the JPIP response message; Step 114, the log information that record this time connects; Step 115, the JPIP response message that step 113 is generated sends to client.The local resource managing process is made regular check on the operating position of local hard drive, if the hard drive space utilization rate is too high, then the image of storing in the hard disk is cleared up.
The JPIP server software of present embodiment is divided into linux version and version of window.Adopt C Plus Plus and GCC compiler to develop on the Linux platform, database adopts MySQL; Adopt the ISAPI expansion of Visual Studio 6.0 exploitations to realize server capability on windows platform, the function of mixed-media network modules mixed-media adopts IIS to realize, database adopts SQL Server.
Second portion JPIP client:
The JPIP client of present embodiment from JPIP server interaction formula ground is extracted the part compressed bit stream data of image to the window interested of image by multithreading according to the user, and image compression bit stream data reorganization back decompress(ion) is shown.The image code stream data that JPIP customer end adopted buffer stores receives comprise DICOM header, code stream master head, splicing block head and packet, and wherein each packet is by these four parameter identifications of resolution, quality layers, component and subregion.The sky of a series of distance of zero mark degree of JPIP customer end adopted wraps rebuilds the JPEG2000 code stream, thereby the image information outside the window interested is provided.
The JPIP client of present embodiment is by forming with lower module: image querying module, image receiver module, JPIP message resolution module, buffer management module, code stream recombination module, JPEG2000 decompression module, image show processing module.Wherein the image querying module is asked by multichannel to JPIP server lookup image code stream according to the interesting image window generation JPIP that the user is provided with; The image receiver module is responsible for receiving the JPIP response message that the JPIP server returns; The JPIP message resolution module is resolved the JPIP response message that the image receiver module receives; The image code stream storage that the buffer management module obtains parsing is in buffering area; The function of code stream recombination module is to extract required packet according to image window to display from buffering area to reassemble into the JPEG2000 code stream; The JPEG2000 decompression module decompresses to the JPEG2000 code stream of reorganization; Image shows that the view data after processing module is to decompress(ion) shows to be handled.
The workflow of the JPIP client of present embodiment is as follows:
The workflow of JPIP client is as shown in Figure 4: step 20, program start; Step 21 is provided with WOI according to the user to the window interested of image; Step 22 judges in the buffering area whether comprised needed code stream, if execution in step 27 then, otherwise execution in step 23; Step 23, send the JPIP request to the JPIP server, extract needed image code stream data, in the JPIP request, comprise the Session ID field, its value is the Session ID that this session distributed for the JPIP server, if the JPIP client is request for the first time, then establish this value and be " new ", if the JPIP client received the image code stream data that the JPIP server returns in last time in the request, then need to comprise the buffer models field in the JPIP request, its value is described the code stream information that last time, request received; Step 24 receives the JPIP response message from the JPIP server; Step 25 is resolved the JPIP response message; Step 26 will be resolved the DICOM header and the JPEG2000 code stream (comprising main head, block head and bag) that obtain by step 25 and be stored in the buffering area; Step 27 is extracted needed bit stream data from buffering area, reorganization JPEG2000 code stream; Step 28 is called the JPEG2000 code stream of JPEG2000 decompression module decompress(ion) reorganization; Step 29, the image behind the demonstration decompress(ion).Step 24 wherein, 25,26,27,28,29 can carry out with three threads respectively simultaneously, and image can adopt the incremental model of resolution → quality → component → position or quality → resolution → component → position to show, to accelerate the display speed of image.
The JPIP client of present embodiment can be applied to the PACS display workstation, also can be applied to wireless PDA.JPIP client software on the PACS display workstation is by Visual Studio 6.0 exploitations; JPIP client software on the wireless PDA adopts Visual Studio 2005 exploitations.
Third part PACS server:
The PACS server is the image center memory cell of PACS system, receives the various medical science DICOM images from each acquisition gateway, and carries out storage and uniform, filing and backup.In store all digital pictures relevant with patient of database in the PACS server, the user can pass through mode quick search such as patient number, patient name, inspection classification, review time and extract patient's image document.The WEB image querying that the present invention has added based on WADO agreement (or other is based on tcp/ip communication agreement) for the PACS server extracts interface as shown in Figure 2, can select Apache or IIS as the WEB server, the WEB service makes the JPIP server can pass through the WADO/HTTP agreement according to image UID inquiry/extraction image as the middleware that connects JPIP server and PACS server.

Claims (1)

1. interactive medical image communication and display packing, it be by between adopt that high-speed local area network connects PACS server and a JPIP server and the system that forms of a plurality of JPIP clients of adopting slow wan (as Internet, GPRS and 3G etc.) to be connected with the JPIP server on realize, it is characterized in that:
A. said medical image compresses processing with JPEG2000, entire image is compressed as single splicing block, wavelet sub-band to each stage resolution ratio of each picture content adopts subregion to divide, partition size on each stage resolution ratio is identical, a subregion comprises three encoding blocks, comprise code stream principal mark head and a splicing block data division in the gained image compression code stream, this splicing block data division comprises a series of packet;
B. low-resolution image preview: client sends request according to the resolution levels of required image to server, server extracts the response package client relevant with the resolution levels of client-requested according to request from the targeted compression image code stream, client receives data, and reorganization JPEG2000 code stream and decompress(ion) show low-resolution image;
C. the high-resolution of area-of-interest shows: after the low-definition version of image had been arranged, client sent the high-resolution request of area-of-interest to server according to user's area-of-interest (as the focus zone); Server extracts from the targeted compression image code stream and the corresponding packet of request, generates response message and returns to client; Client receives data, and reorganization JPEG2000 code stream and decompress(ion) show the high-definition picture of area-of-interest.
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