CN101279016A - Oral medicament for curing craniocerebral injury associated with hydrocephalus - Google Patents
Oral medicament for curing craniocerebral injury associated with hydrocephalus Download PDFInfo
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- CN101279016A CN101279016A CNA2008100164097A CN200810016409A CN101279016A CN 101279016 A CN101279016 A CN 101279016A CN A2008100164097 A CNA2008100164097 A CN A2008100164097A CN 200810016409 A CN200810016409 A CN 200810016409A CN 101279016 A CN101279016 A CN 101279016A
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Abstract
The invention relates to an internal medicine for curing cerebral edema caused by craniocerebral injury, which pertains to traditional Chinese medicine preparation. The internal medicine of the invention is characterized in that: the effective components of the internal medicine comprises the raw pharamaceutical materials with the following parts by weight: 15-45 parts of Indian buead, 10-24 parts of polyporus, 10-24 parts of largehead atractylodes rhizome, 15-45 parts of water plaintain, 8-18 parts of twotooth achyranthes root, 15-45 parts of motherwort herb, 15-45 parts of raidx astragali, 8-18 parts of rhubarb, 8-18 parts of peach seed, 8-18 parts of rhizomaligustici chuanxiong, 10-36 parts of radix salivae miltiorrhizae, 8-18 parts of safflower, 8-18 parts of red paeony root, 10-24 parts of kudzuvine root, 8-18 parts of thinleaf milkwort root-bark and 8-18 parts of drug sweetflag rhizome. The preparation method of the internal medicine comprises the steps: all the pharamaceutical raw materials (except rhubarb) are mixed in a casserole, appropriate amount of water is added for pickling, the boiling by strong fire is firstly carried out, the rhubarb is added, the liquid medicine is filtered after half an hour, the boiling by small fire is carried out, and the liquid medicine is filtered; the two liquid medicines are mixed and cooled. The method of administration is that: the internal medicine is orally taken three times a day for conscious patients, and is injected by using a gastric tube three times a day for narcose patients. The cure rate of the composition of the invention for curing traumatic brain edema is 96%, and the effective rate is 100%.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, is a kind of medicine of orally taken for curing craniocerebral injury associated with hydrocephalus specifically.
Background technology
In recent years, along with the development of China's communication, domestic private vehicular traffic increase and craniocerebral trauma patient that various social cause causes has the trend of being on the increase.Traumatic brain edema is craniocerebral injury death and major cause of morbidity, and its genesis mechanism is very complicated, and all multifactor weave ins cause jointly.If traumatic brain edema can not get control, can make nervous tissue's regression and atrophy, the aggravation delayed ischemic neurological deficits.And the intracranial pressure that cerebral edema causes continues to increase, and finally may cause cerebral hernia, is one of early stage main causes of death of craniocerebral trauma.Therefore, in the craniocerebral trauma Comprehensive Treatment, the early prevention and treatment cerebral edema is extremely important.
At present, the scheme of treatment craniocerebral injury associated with hydrocephalus mainly is: in the whole process of craniocerebral trauma treatment, must keep the patient respiratory road unobstructed, and keep effective respiratory function.Correct dysarteriotony,, keep effective regional cerebral blood flow to improve cerebral perfusion pressure.Should use calcium ion antagonist early to the craniocerebral trauma patient.By the medicine dehydration therapy, alleviate cerebral edema.Though medicine is many at present, do not cost an arm and a leg, be exactly that effect is undesirable.
Summary of the invention
The object of the present invention is to provide a kind of medicine of orally taken for curing craniocerebral injury associated with hydrocephalus, it has overcome the deficiency of existing medicine, can be quick, effectively treat craniocerebral injury associated with hydrocephalus, and cost is low.
The technical scheme that technical solution problem of the present invention is taked is:
The medicine of this kind orally taken for curing craniocerebral injury associated with hydrocephalus, it is characterized in that the crude drug of making effective ingredient by following weight portion is: Poria 15～45, Polyporus 10～24, the Rhizoma Atractylodis Macrocephalae 10～24, Rhizoma Alismatis 15～45, Radix Achyranthis Bidentatae 8～18, Herba Leonuri 15～45, the Radix Astragali 15～45, Radix Et Rhizoma Rhei 8～18, Semen Persicae 8～18, Rhizoma Chuanxiong 8～18, Radix Salviae Miltiorrhizae 10～36, Flos Carthami 8～18, Radix Paeoniae Rubra 8～18, Radix Puerariae 10～24, Radix Polygalae 8～18 and Rhizoma Acori Graminei 8～18.
The further technical scheme of the present invention is: the medicine of this kind orally taken for curing craniocerebral injury associated with hydrocephalus, it is characterized in that the crude drug of making effective ingredient by following weight portion is: Poria 30, Polyporus 15, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Alismatis 30, Radix Achyranthis Bidentatae 12, Herba Leonuri 30, the Radix Astragali 30, Radix Et Rhizoma Rhei 10, Semen Persicae 10, Rhizoma Chuanxiong 10, Radix Salviae Miltiorrhizae 30, Flos Carthami 10, Radix Paeoniae Rubra 10, Radix Puerariae 15, Radix Polygalae 10 and Rhizoma Acori Graminei 10.
Preparation and instructions of taking:
Each raw material of the present invention all is pure natural property, can be buied by pharmacy.Its application process is: various medicine materials (except the Radix Et Rhizoma Rhei) are mixed in the marmite, add water and soak in right amount; Elder generation's intense fire back that is fried boiling adds Radix Et Rhizoma Rhei and leaches medicinal liquid half an hour, reuse half an hour at a simmer, leaches medicinal liquid again.Twice medicinal liquid mixes, cools completely.Clear-headed patient divides 3 clothes every day down, and coma patient can divide 3 injections every day through stomach tube.
The invention has the beneficial effects as follows:
Medicinal liquid is for oral administration after 15～20 minutes, enhanced borborygmus can appear, can occur thin feces after 40 minutes～1 hour discharges, and having the cacosmia flavor, defecation frequency and output, do not wait, along with the discharge of thin feces, cerebral edema improves gradually, show as irritable patient and become quiet gradually, the patient reaction takes a turn for the better gradually, and the GCS scoring increases gradually.And it is low to be the raw material of Chinese medicine cost, and the patient burden is light.
Traumatic brain edema is the wet category of disease in the traditional Chinese medical science.Studying carefully its pathogenesis, is in stagnant blood stays, paralysis resistance passages through which vital energy circulates, and the QI and blood paralysis is stagnant, and water is wet not to be transported, and gives birth to brains in the phlegm-damp and loses foster.Old pathogen gas is this with congestion, is mark with the phlegm-damp.Modern medicine thinks, the pathological change of traumatic brain edema be too much moisture accumulation in brain cell or ECS, it is caused by trickle circulatory disturbance.Therefore the phlegm reduction of blood circulation promoting inducing diuresis to remove edema is the key of treatment.The side is with Rhizoma Chuanxiong, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Semen Persicae, Flos Carthami, Radix Et Rhizoma Rhei, Radix Puerariae blood circulation promoting and blood stasis dispelling, to control the blood stasis of brain; Poria, Polyporus, the Rhizoma Atractylodis Macrocephalae, Rhizoma Alismatis, Ramulus Cinnamomi, the Radix Astragali, Radix Achyranthis Bidentatae, Herba Leonuri inducing diuresis to remove edema are so that the god's of unit wet descending the leaking of heresy of internal organs water.Two methods are share, and are the pathogenesis that hits, and the merit of playing blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema.Except that function of promoting blood circulation to disperse blood clots is arranged, rushing down detoxifcation down in addition except that damp and hot effect under simultaneously behind the Radix Et Rhizoma Rhei, foul smell is descended, poison gets clearly; Radix Polygalae, Rhizoma Acori Graminei consciousness-restoring and orifice-opening; More than all medicine fit applications blood stasis is gone, edema disappears, and is clearheaded.
The present composition is treated traumatic brain edema patient 100 examples, cure rate 96%, effective percentage 100% altogether.Model case is as follows:
Case 1, Zhang, the man, 32 years old, because of traffic accident hurts Heavy craniocerebral injury, stupor, GCS5 branch, cranium brain CT: multiple brain contusion.Subarachnoid hemorrhage, cerebral edema is serious, obeys 6 doses of medicaments of the present invention, and mind is changeed clearly gradually, recovery from illness.
Case 2, Lee, man, 23 years old.Remain unconscious after the traffic accident wound, the GCS7 branch, cranium brain CT shows: multiple contusion and laceration of brain, acute subdural hematoma, subarachnoid hemorrhage.Obey 8 doses of medicaments of the present invention, mind is changeed clearly gradually, recovery from illness.
Case 3, Wang, man, 28 years old.The occurrences in human life of remaining unconscious after the Falling Injury, the GCS6 branch, cranium brain CT shows: two frontal lobe brain contusion, subarachnoid hemorrhage.Obey 8 doses of medicaments of the present invention, mind is changeed clearly gradually, recovery from illness.
Case 4, Guo, woman, 36 years old, the occurrences in human life of remaining unconscious after vehicle is hindered.The GCS7 branch, cranium brain CT shows: left side volume, leaf brain contusion are split subarachnoid hemorrhage.Obey 8 doses of medicaments of the present invention, mind is changeed clearly gradually, recovery from illness.
Case 5, Liu, the man, 33 years old, the occurrences in human life of remaining unconscious after vehicle is hindered, the GCS5 branch, cranium brain CT shows: multiple brain contusion.Subarachnoid hemorrhage, cerebral edema is serious, obeys 10 doses of medicaments of the present invention, and mind is changeed clearly gradually, recovery from illness.
In clinical, also find medicine of the present invention such as fit applications mannitol, better effects if.
The specific embodiment
Example 1: a kind of medicine of orally taken for curing craniocerebral injury associated with hydrocephalus, the crude drug of making effective ingredient by following weight portion is: Poria 15, Polyporus 10, the Rhizoma Atractylodis Macrocephalae 10, Rhizoma Alismatis 15, Radix Achyranthis Bidentatae 8, Herba Leonuri 15, the Radix Astragali 15, Radix Et Rhizoma Rhei 8, Semen Persicae 8, Rhizoma Chuanxiong 8, Radix Salviae Miltiorrhizae 10, Flos Carthami 8, Radix Paeoniae Rubra 8, Radix Puerariae 10, Radix Polygalae 8 and Rhizoma Acori Graminei 8.
Each crude drug of the present invention all is pure natural property, can be buied by pharmacy.Its application process is: various medicine materials (except the Radix Et Rhizoma Rhei) are mixed in the marmite, add water and soak in right amount; Elder generation's intense fire back that is fried boiling adds Radix Et Rhizoma Rhei and leaches medicinal liquid half an hour, reuse half an hour at a simmer, leaches medicinal liquid again.Twice medicinal liquid mixes, cools completely.Clear-headed patient divides 3 clothes every day down, and coma patient can divide 3 injections every day through stomach tube.
Example 2: a kind of medicine of orally taken for curing craniocerebral injury associated with hydrocephalus, the crude drug of making effective ingredient by following weight portion is: Poria 45, Polyporus 24, the Rhizoma Atractylodis Macrocephalae 24, Rhizoma Alismatis 45, Radix Achyranthis Bidentatae 18, Herba Leonuri 45, the Radix Astragali 45, Radix Et Rhizoma Rhei 18, Semen Persicae 18, Rhizoma Chuanxiong 18, Radix Salviae Miltiorrhizae 36, Flos Carthami 18, Radix Paeoniae Rubra 18, Radix Puerariae 24, Radix Polygalae 18 and Rhizoma Acori Graminei 18.Its application process is with example 1.
Example 3: a kind of medicine of orally taken for curing craniocerebral injury associated with hydrocephalus, the crude drug of making effective ingredient by following weight portion is: Poria 20, Polyporus 20, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Alismatis 30, Radix Achyranthis Bidentatae 12, Herba Leonuri 30, the Radix Astragali 30, Radix Et Rhizoma Rhei 12, Semen Persicae 12, Rhizoma Chuanxiong 12, Radix Salviae Miltiorrhizae 20, Flos Carthami 12, Radix Paeoniae Rubra 12, Radix Puerariae 18, Radix Polygalae 12 and Rhizoma Acori Graminei 12.Its application process is with example 1.
Example 4: a kind of medicine of orally taken for curing craniocerebral injury associated with hydrocephalus, the crude drug of making effective ingredient by following weight portion is: Poria 45, Polyporus 10, the Rhizoma Atractylodis Macrocephalae 12, Rhizoma Alismatis 45, Radix Achyranthis Bidentatae 8, Herba Leonuri 40, the Radix Astragali 15, Radix Et Rhizoma Rhei 18, Semen Persicae 12, Rhizoma Chuanxiong 8, Radix Salviae Miltiorrhizae 36, Flos Carthami 16, Radix Paeoniae Rubra 10, Radix Puerariae 24, Radix Polygalae 8 and Rhizoma Acori Graminei 18.Its application process is with example 1.
Example 5: a kind of medicine of orally taken for curing craniocerebral injury associated with hydrocephalus, the crude drug of making effective ingredient by following weight portion is: Poria 15, Polyporus 24, the Rhizoma Atractylodis Macrocephalae 10, Rhizoma Alismatis 30, Radix Achyranthis Bidentatae 8, Herba Leonuri 45, the Radix Astragali 20, Radix Et Rhizoma Rhei 18, Semen Persicae 8, Rhizoma Chuanxiong 8, Radix Salviae Miltiorrhizae 12, Flos Carthami 16, Radix Paeoniae Rubra 24, Radix Puerariae 18, Radix Polygalae 18 and Rhizoma Acori Graminei 12.Its application process is with example 1.
Example 6: a kind of medicine of orally taken for curing craniocerebral injury associated with hydrocephalus, the crude drug of making effective ingredient by following weight portion is: Poria 30, Polyporus 15, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Alismatis 30, Radix Achyranthis Bidentatae 12, Herba Leonuri 30, the Radix Astragali 30, Radix Et Rhizoma Rhei 10, Semen Persicae 10, Rhizoma Chuanxiong 10, Radix Salviae Miltiorrhizae 30, Flos Carthami 10, Radix Paeoniae Rubra 10, Radix Puerariae 15, Radix Polygalae 10 and Rhizoma Acori Graminei 10.
Claims (2)
1, a kind of medicine of orally taken for curing craniocerebral injury associated with hydrocephalus, it is characterized in that the crude drug of making effective ingredient by following weight portion is: Poria 15～45, Polyporus 10～24, the Rhizoma Atractylodis Macrocephalae 10～24, Rhizoma Alismatis 15～45, Radix Achyranthis Bidentatae 8～18, Herba Leonuri 15～45, the Radix Astragali 15～45, Radix Et Rhizoma Rhei 8～18, Semen Persicae 8～18, Rhizoma Chuanxiong 8～18, Radix Salviae Miltiorrhizae 10～36, Flos Carthami 8～18, Radix Paeoniae Rubra 8～18, Radix Puerariae 10～24, Radix Polygalae 8～18 and Rhizoma Acori Graminei 8～18.
2, the medicine of a kind of orally taken for curing craniocerebral injury associated with hydrocephalus according to claim 1, it is characterized in that the crude drug of making effective ingredient by following weight portion is: Poria 30, Polyporus 15, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Alismatis 30, Radix Achyranthis Bidentatae 12, Herba Leonuri 30, the Radix Astragali 30, Radix Et Rhizoma Rhei 10, Semen Persicae 10, Rhizoma Chuanxiong 10, Radix Salviae Miltiorrhizae 30, Flos Carthami 10, Radix Paeoniae Rubra 10, Radix Puerariae 15, Radix Polygalae 10 and Rhizoma Acori Graminei 10.
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2008100164097A CN101279016A (en) | 2008-05-29 | 2008-05-29 | Oral medicament for curing craniocerebral injury associated with hydrocephalus |
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Cited By (8)
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| CN101474022B (en) * | 2009-01-13 | 2010-08-25 | 赵青菊 | External-use Chinese medicine refreshment pillow for treating coma patient with brain trauma |
| WO2010110755A1 (en) * | 2009-03-27 | 2010-09-30 | Moleac Pte. Ltd. | Therapy for promoting cell growth |
| CN101972452A (en) * | 2010-10-26 | 2011-02-16 | 左权县蓝天中药科技开发有限公司 | Medicament for treating cerebral trauma associated tardive cranial nerve dysfunction |
| CN101843889B (en) * | 2009-03-25 | 2012-02-15 | 上海交通大学医学院附属第九人民医院 | Medicament for treating lymphedema and venous edema and application thereof |
| CN104491461A (en) * | 2015-01-15 | 2015-04-08 | 青岛大学附属医院 | Externally-used traditional Chinese medicines formula for preventing chronic subdural haematoma postoperative complications and preparation method |
| CN104587199A (en) * | 2014-12-30 | 2015-05-06 | 青岛大学附属医院 | traditional Chinese medicine composition for treating chronic subdural hematoma, as well as preparation method thereof |
| CN104815075A (en) * | 2015-05-14 | 2015-08-05 | 赵新军 | Traditional Chinese medicine composition for treating encephaledema after cerebral trauma |
| CN116966247A (en) * | 2023-02-07 | 2023-10-31 | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | Traditional Chinese medicine composition and medicine for treating cerebral edema |
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2008
- 2008-05-29 CN CNA2008100164097A patent/CN101279016A/en active Pending
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101474022B (en) * | 2009-01-13 | 2010-08-25 | 赵青菊 | External-use Chinese medicine refreshment pillow for treating coma patient with brain trauma |
| CN101843889B (en) * | 2009-03-25 | 2012-02-15 | 上海交通大学医学院附属第九人民医院 | Medicament for treating lymphedema and venous edema and application thereof |
| US9289459B2 (en) | 2009-03-27 | 2016-03-22 | Moleac Pte. Ltd. | Therapy for promoting cell growth |
| WO2010110755A1 (en) * | 2009-03-27 | 2010-09-30 | Moleac Pte. Ltd. | Therapy for promoting cell growth |
| US10188688B2 (en) | 2009-03-27 | 2019-01-29 | Moleac Pte. Ltd. | Therapy for promoting cell growth |
| RU2586302C2 (en) * | 2009-03-27 | 2016-06-10 | Молеак Пте. Лтд. | Therapy for stimulation of cell growth |
| CN101972452A (en) * | 2010-10-26 | 2011-02-16 | 左权县蓝天中药科技开发有限公司 | Medicament for treating cerebral trauma associated tardive cranial nerve dysfunction |
| CN104587199B (en) * | 2014-12-30 | 2017-09-01 | 青岛大学附属医院 | It is a kind of to treat Chinese medicine composition of CSDH and preparation method thereof |
| CN104587199A (en) * | 2014-12-30 | 2015-05-06 | 青岛大学附属医院 | traditional Chinese medicine composition for treating chronic subdural hematoma, as well as preparation method thereof |
| CN104491461B (en) * | 2015-01-15 | 2017-11-07 | 青岛大学附属医院 | Prevent the external application Chinese medicine prescription and preparation method of CSDH postoperative complications |
| CN104491461A (en) * | 2015-01-15 | 2015-04-08 | 青岛大学附属医院 | Externally-used traditional Chinese medicines formula for preventing chronic subdural haematoma postoperative complications and preparation method |
| CN104815075A (en) * | 2015-05-14 | 2015-08-05 | 赵新军 | Traditional Chinese medicine composition for treating encephaledema after cerebral trauma |
| CN104815075B (en) * | 2015-05-14 | 2019-03-26 | 赵新军 | A kind of Chinese medicine composition for treating craniocerebral injury brain edema |
| CN116966247A (en) * | 2023-02-07 | 2023-10-31 | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | Traditional Chinese medicine composition and medicine for treating cerebral edema |
| CN116966247B (en) * | 2023-02-07 | 2024-03-22 | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | Traditional Chinese medicine composition and medicine for treating cerebral edema |
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Open date: 20081008 |