CN100478007C - Plaster for treating traumatic injuries and rheumatism, and its prepn. method - Google Patents
Plaster for treating traumatic injuries and rheumatism, and its prepn. method Download PDFInfo
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- CN100478007C CN100478007C CNB2005100815060A CN200510081506A CN100478007C CN 100478007 C CN100478007 C CN 100478007C CN B2005100815060 A CNB2005100815060 A CN B2005100815060A CN 200510081506 A CN200510081506 A CN 200510081506A CN 100478007 C CN100478007 C CN 100478007C
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Abstract
A Chinese medicine in the form of plaster for treating bone fracture, injury, rheumatism and hyperplasia is prepared from 10 Chinese-medicinal materials including peach kernel, safflower, myrrh, ground bettle, etc through pulverizing, decocting oil, mixing, stirring, immersing in flowing water for 10 hr, and coating it on cloth substrate.
Description
Technical field:
The present invention relates to a kind of externally applied ointment of making by pure Chinese medicine and preparation method thereof, specifically a kind of pure Chinese medicine externally applied ointment for the treatment of traumatic injury, rheumatalgia, hyperosteogeny disease and preparation method thereof.
Background technology:
Traumatic injury, rheumatalgia, hyperosteogeny are clinical a kind of commonly encountered diseases, frequently-occurring disease, and as arthritis, bony spur, prolapse of intervertebral disc etc., theory of Chinese medical science thinks that this type of disease all belongs to the disease of rheumatism and arthritis.The patient of the present rheumatic osteoarthropathy of China has about 100,000,000 people approximately, and pain discomfort during morbidity brings inconvenience for work and life, and directly influence is healthy when serious.Traumatic injury, rheumatalgia, hyperosteogeny are for oral administration, the medicine of external is a lot of though treat at present, lack curative effect more satisfactory medicine, especially externally applied ointment, and most externally applied ointments exist based on pain relieving, cure the symptoms, not the disease, easily the problem that recurs.In addition, though traditional externally applied ointment has its distinctive feature, medicine can directly act on focus, evident in efficacy, but the conventional pastes medicament preparation also has weak point, such as traditional high temperature extraction method of wasting lamp oil by not sleeping at night a lot of effective ingredient in the medicine are destroyed, reduced drug effect, and the oil refining that the long period continues prepares generation " fire-toxin " in the plaster process, oxidation Decomposition goes out products such as ketone excitatory, aldehyde and lower fatty acid in the medicine oil, can form stimulation to skin, produce red and swollen, scratch where it itches, side effect such as pain.
Summary of the invention:
The objective of the invention is deficiency at above-mentioned treatment traumatic injury, rheumatalgia, externally applied ointment for treating hyperosteogeny existence, act on motherland's Chinese medicine theory and the externally applied ointment invaluable experience aspect treatment traumatic injury, rheumatalgia, hyperosteogeny, research repeatedly through the more than ten years, meticulous screening of medicaments, by a large amount of clinical observations, provide a kind of new formula combination and preparation method thereof.
Technical scheme of the present invention is:
A kind of plaster for treating traumatic injuries and rheumatism comprises following raw materials in weight portion medical material:
Semen Strychni (processed) 0.2-0.9g; Semen Persicae 2-5g; Flos Carthami 3-15g; Radix Clematidis 5-15g; Olibanum 5-10g; Myrrha 5-10g; Eupolyphaga Seu Steleophaga 2-10g; Sanguis Draxonis 0.2-0.5g; Radix Et Rhizoma Rhei 5-10g; River Os Draconis 5-15g.
The said medicine raw material according to the best prescription of weight portion meter is:
Semen Strychni (processed) 0.9g; Semen Persicae 3g; Flos Carthami 10g; Radix Clematidis 10g; Olibanum 10g; Myrrha 10g; Eupolyphaga Seu Steleophaga 10g; Sanguis Draxonis 0.5g; Radix Et Rhizoma Rhei 8g; River Os Draconis 8g.
The preparation method of above-mentioned plaster for treating traumatic injuries and rheumatism is:
1, get raw medicinal material by weight ratio, and raw medicinal material is ground into 120 order powders, standby;
2, with slow fire Oleum Sesami is heated to 200-300 ℃, when Oleum Sesami decocts the cyan cigarette of emerging more shallow, add into cream base matter---Plumbum preparatium, oily, red ratio is 2.5: 1, stirs, red oil is endured to dripping into pearl, tack-free, when cooling is not hardened till;
3, the 1st step was produced standby powder spice in the red oil of being endured, red oil is 1.5-2 with the allotment ratio of spice: 1, stir rapidly, and form semi-solid soft dough shape;
4, the ointment of preparing was steeped 10 hours releasing fire-toxin with the cold flow water logging;
5, ointment is heated to the 60-80 degree is molten to be opened, is coated on the cloth, be coated with plaster 7g on every plaster stype, finish preparation process.
The principles of formulating prescriptions of the present invention are by bringing into play synergism between the compatibility medical material, carry out function and integrate, realize blood circulation promoting and blood stasis dispelling, heat clearing away eliminating stagnation, anti-inflammatory analgetic, expelling wind and removing dampness, putrefaction-removing granulation-promoting, making lesion tissue recover normal therapeutic efficiency.
Semen Strychni (processed), Semen Persicae, Flos Carthami, Radix Clematidis are monarch drug in the prescription, in the side, play dispelling wind and removing obstruction in the collateral, blood circulation promoting and blood stasis dispelling, the mastery reaction of reducing swelling and alleviating pain, wherein Semen Strychni (processed) can dispelling wind and relieving pain, relaxing muscles and tendons and activating QI and blood in the collateral, Semen Persicae energy blood circulation promoting and blood stasis dispelling, promoting blood circulation to restore menstrual flow, Flos Carthami energy reducing swelling and alleviating pain, activating blood circulation to dissipate blood stasis, Radix Clematidis energy wind-damp dispelling, the meridian dredging.Modern pharmacology shows that the Semen Strychni (processed) main component is alkaloid-Strychnine, has excitement and refreshes oneself, Detoxication; Semen Persicae contains amygdalin, mandelic acid, fatty oil and vitamin B1, has the blood stasis dispelling effect; Flos Carthami contains Carthamus yellow, carthamone, saffloside, Flos Carthami sugar etc., has the reducing swelling and alleviating pain effect, helps osteoarticular reparation; Radix Clematidis contains anemonin, Radix Pulsatillae alcohol, and zoopery has certain anesthetic action, has rheumatism, analgesic effect;
Olibanum, Myrrha are ministerial drug, play dispelling wind and removing obstruction in the collateral in the side, blood circulation promoting and blood stasis dispelling, the assosting effect of reducing swelling and alleviating pain, wherein Olibanum can invigorate blood circulation, circulation of qi promoting, pain relieving, Myrrha can the promoting blood circulation to remove blood stasis analgesia, the convergence antiinflammatory.Modern pharmacology shows that Olibanum contains boswellic acid, lactic acid fat hydrocarbon, Olibanum subacid, boswellic acid, has the active effect of blood stasis dispelling; Myrrha is resinous, volatile oil, natural gum etc., and the power of blood stasis removing and clots absorbing is arranged, and has convergence and antiinflammation.
Eupolyphaga Seu Steleophaga, Sanguis Draxonis, Radix Et Rhizoma Rhei are left medicine, play removing blood stasis in the side, heat-clearing and toxic substances removing, and the auxilliary left side effect of pain relieving granulation promoting, wherein Eupolyphaga Seu Steleophaga has removing blood stasis, the crux function of loosing, the hemostasis of Sanguis Draxonis energy, pain relieving, blood activating and promoting tissue regeneration, Radix Et Rhizoma Rhei energy blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing.Modern pharmacology shows that Eupolyphaga Seu Steleophaga contains fatty acid, amino acids, volatilization wet goods, has the thrombosis of separating effect; Sanguis Draxonis contains dracorubin, benzoic acid etc., has hemostasis, pain relieving, promoting muscle growth functions; Radix Et Rhizoma Rhei contains anthraglycosides and the dissociated anthraquinone thing that spreads out, resin, and saccharide and amount starch, mucus and calcium oxalate, emodin etc. have antibiotic astriction.
The river Os Draconis have convergence, antiinflammatory, hemostasis and relaxing muscles and tendons and activating QI and blood in the collateral, remove the effect of rheumatism, enrich the whole pharmacodynamic feature of prescription, play envoy's effect in the side.Modern pharmacology shows that it contains calcium carbonate, calcium phosphate, can restrain antiinflammatory, reduces secretions and oozes out.
In addition, one-tenth cream base matter---Plumbum preparatium also has the effect of mediation, convergence, antiinflammatory, granulation promoting.
Beneficial effect:, make medicine give full play to drug effect because medicine of the present invention is paid attention to the interactive integration function of cooperative drug.Reach to pathogenesis reason prescription according to rheumatism osteoarthritis, the traumatic injury cause of disease, medicine among the other side carries out herbal pharmacology and modern pharmacological research, pays attention to taking stopgap measures on combining with effecting a permanent cure, to the treatment traumatic injury, rheumatic arthritis, arthralgia, waist leg gall, hyperosteogeny, cervical spondylosis, scapulohumeral periarthritis, mastitis, curative effect of disease such as cyclomastopathy are definite.And medicine instant effect of the present invention, short treating period is difficult for recurrence; With low cost, easy to use, be easy to be accepted by the patient.
Medicine of the present invention adopts unique preparation method, overcome the deficiency that the conventional pastes medicament preparation exists to a great extent, not only having significantly reduced effective ingredient is at high temperature destroyed, particularly volatile active chemicals such as resin, alkaloid, glycoside are not destroyed, keep drug effect abundant, and make to temper and produce harmful substance in the medicine oil process and fall sharply, it is red, swollen greatly to have reduced the skin that skin irritation is produced, the anaphylaxiss such as pain of scratching where it itches have reached basically and have had no side effect.
The specific embodiment:
Embodiment 1
A kind of plaster for treating traumatic injuries and rheumatism comprises following raw materials in weight portion medical material:
Semen Strychni (processed) 0.2g; Semen Persicae 5g; Flos Carthami 3g; Radix Clematidis 5g; Olibanum 5g; Myrrha 10g; Eupolyphaga Seu Steleophaga 2g; Sanguis Draxonis 0.4g; Radix Et Rhizoma Rhei 5g; River Os Draconis 15g.
The preparation method of the plaster for treating traumatic injuries and rheumatism of said components is:
1, get raw medicinal material by weight ratio, and raw medicinal material is ground into 120 order powders, standby;
2, with slow fire Oleum Sesami is heated to 200-300 ℃ of oil temperature, when Oleum Sesami decocts the cyan cigarette of emerging more shallow, add into cream base matter---Plumbum preparatium, oily, red ratio is 2.5: 1, stir, red oil endured to dripping into pearl, tack-free, when cooling is not hardened till;
3, the 1st step was produced standby powder spice in the red oil of being endured, red oil is 1.5-2 with the allotment ratio of spice: 1, stir rapidly, and form semi-solid soft dough shape;
4, the ointment of preparing is soaked 10 hours releasing fire-toxin with cooler flowing water;
5, ointment is heated to the 60-80 degree is molten to be opened, is coated on the cloth, be coated with plaster 7g on every plaster stype, finish preparation process.
Using method: wipe pars affecta skin clearly with Rhizoma Zingiberis Recens, plaster is heated to deliquescing (about 40 ℃) is affixed on the affected part, 7 days is a course of treatment, anemia of pregnant woman, skin allergy person forbidding.
The treatment case: traumatic injury 5 examples, wherein male 2 examples, age 13-54 year, women 3 examples, age 38-65 year, treated for 2 courses of treatment, cure 4 examples, produce effects 1 example; Rheumatalgia 18 examples, wherein male 7 examples, in age 37-56 year, women 11 examples in age 45-62 year, treated for 4 courses of treatment, cure rate 14 examples, produce effects 4 examples; Hyperosteogeny 6 examples, wherein male 3 examples, age 43-56 year, women 3 examples, age 41-47 year, treated for 2 courses of treatment, cure 3 examples, produce effects 2 examples, invalid 1 example.
Embodiment 2
A kind of plaster for treating traumatic injuries and rheumatism comprises following raw materials in weight portion medical material:
Semen Strychni (processed) 0.5g; Semen Persicae 2g; Flos Carthami 5g; Radix Clematidis 15g; Olibanum 7g; Myrrha 5g; Eupolyphaga Seu Steleophaga 6g; Sanguis Draxonis 0.2g; Radix Et Rhizoma Rhei 10g; River Os Draconis 5g.
Preparation method is identical with embodiment 1.
Using method: wipe pars affecta skin clearly with Rhizoma Zingiberis Recens, plaster is heated to deliquescing (about 40 ℃) is affixed on the affected part, 7 days is a course of treatment, anemia of pregnant woman, skin allergy person forbidding.
The treatment case: traumatic injury 4 examples, wherein male 1 example, 45 years old age, women 3 examples, age 15-68 year, treated for 2 courses of treatment, cure 3 examples, produce effects 1 example; Rheumatalgia 22 examples, wherein male 15 examples, age 25-55 year, women 7 examples, treatment 2-5 course of treatment, are cured 17 examples, produce effects 5 examples at age 43-64 year; Hyperosteogeny 9 examples, wherein male 4 examples, age 42-57 year, women 5 examples, treatment 4-6 course of treatment, are cured 5 examples, produce effects 2 examples, invalid 2 examples at age 37-61 year.
Embodiment 3
A kind of plaster for treating traumatic injuries and rheumatism comprises following raw materials in weight portion medical material:
Semen Strychni (processed) 0.9g; Semen Persicae 3g; Flos Carthami 10g; Radix Clematidis 10g; Olibanum 10g; Myrrha 10g; Eupolyphaga Seu Steleophaga 10g; Sanguis Draxonis 0.5g; Radix Et Rhizoma Rhei 8g; River Os Draconis 8g.
Preparation method is identical with embodiment 1.
Using method: wipe pars affecta skin clearly with Rhizoma Zingiberis Recens, plaster is heated to deliquescing (about 40 ℃) is affixed on the affected part, 7 days is a course of treatment, anemia of pregnant woman, skin allergy person forbidding.
The treatment case: traumatic injury 2 examples, wherein male 2 examples, age 18-35 year, treated for 1 course of treatment, cure 2 examples; Rheumatalgia 49 examples, wherein male 23 examples, age 24-66 year, women 26 examples, treatment 3-5 course of treatment, are cured 39 examples, produce effects 10 examples at age 28-72 year; Hyperosteogeny 12 examples, wherein male 5 examples, age 46-57 year, women 7 examples, treatment 4-7 course of treatment, are cured 9 examples, produce effects 3 examples at age 36-68 year.
Use plaster for treating traumatic injuries and rheumatism by three groups of embodiment, 127 routine different patients are carried out systematic observation and treatment, statistical results show, total effective rate is 97.64%; Wherein cure 96 examples, account for 75.6%; Produce effects 28 examples account for 22.04%; Invalid 3 examples account for 2.36%.
Claims (3)
1, a kind of externally applied ointment for the treatment of traumatic injury, rheumatism and hyperosteogeny disease is characterized in that the pharmacodynamic raw materials of this plaster is:
Semen Strychni (processed) 0.2-0.9g; Semen Persicae 2-5g; Flos Carthami 3-15g; Radix Clematidis 5-15g; Olibanum 5-10g; Myrrha 5-10g; Eupolyphaga Seu Steleophaga 2-10g; Sanguis Draxonis 0.2-0.5g; Radix Et Rhizoma Rhei 5-10g; River Os Draconis 5-15g.
2, externally applied ointment according to claim 1 is characterized in that the pharmacodynamic raw materials of this plaster is:
Semen Strychni (processed) 0.9g; Semen Persicae 3g; Flos Carthami 10g; Radix Clematidis 10g; Olibanum 10g; Myrrha 10g; Eupolyphaga Seu Steleophaga 10g; Sanguis Draxonis 0.5g; Radix Et Rhizoma Rhei 8g; River Os Draconis 8g.
3, the method for preparing claim 1 or 2 described externally applied ointments is:
A, get raw medicinal material by weight ratio, and raw medicinal material is ground into 120 order powder, standby;
B, with slow fire Oleum Sesami is heated to 200-300 ℃ of oil temperature, when Oleum Sesami decocts the cyan cigarette of emerging more shallow, add into cream base matter Plumbum preparatium, oily, red ratio is 2.5: 1, stirs, red oil is endured to dripping into pearl, tack-free, when cooling is not hardened till;
C, a step is produced standby powder spice in the red oil of being endured, red oil is 1.5-2 with the allotment ratio of spice: 1, stir rapidly, and form semi-solid soft dough shape;
D, ointment cold water flush, 10 hours releasing fire-toxin of immersion with preparing;
E, ointment is heated to the 60-80 degree is molten to be opened, is coated on the cloth, it is 7g that every subsides are coated with dose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100815060A CN100478007C (en) | 2005-05-28 | 2005-06-25 | Plaster for treating traumatic injuries and rheumatism, and its prepn. method |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200510074566.X | 2005-05-28 | ||
| CN200510074566 | 2005-05-28 | ||
| CNB2005100815060A CN100478007C (en) | 2005-05-28 | 2005-06-25 | Plaster for treating traumatic injuries and rheumatism, and its prepn. method |
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| Publication Number | Publication Date |
|---|---|
| CN1868510A CN1868510A (en) | 2006-11-29 |
| CN100478007C true CN100478007C (en) | 2009-04-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2005100815060A Expired - Fee Related CN100478007C (en) | 2005-05-28 | 2005-06-25 | Plaster for treating traumatic injuries and rheumatism, and its prepn. method |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111714593A (en) * | 2020-08-14 | 2020-09-29 | 徐州成 | Plaster for treating arthralgia and myalgia and preparation method |
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- 2005-06-25 CN CNB2005100815060A patent/CN100478007C/en not_active Expired - Fee Related
Non-Patent Citations (4)
| Title |
|---|
| 中药成方制剂中风湿病相关方剂数据库的建立与处方分析. 方勇飞等.中国药方，第14卷第11期. 2003 |
| 中药成方制剂中风湿病相关方剂数据库的建立与处方分析. 方勇飞等.中国药方，第14卷第11期. 2003 * |
| 类风湿性关节炎的中医药治疗概况. 王鸿宾.甘肃中医，第11卷第4期. 1998 |
| 类风湿性关节炎的中医药治疗概况. 王鸿宾.甘肃中医，第11卷第4期. 1998 * |
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| CN1868510A (en) | 2006-11-29 |
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Granted publication date: 20090415 Termination date: 20100625 |