CN100346755C - Two-way multi-channel artificial cochlea system with on-chip signal processor - Google Patents
Two-way multi-channel artificial cochlea system with on-chip signal processor Download PDFInfo
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- CN100346755C CN100346755C CNB2005100120023A CN200510012002A CN100346755C CN 100346755 C CN100346755 C CN 100346755C CN B2005100120023 A CNB2005100120023 A CN B2005100120023A CN 200510012002 A CN200510012002 A CN 200510012002A CN 100346755 C CN100346755 C CN 100346755C
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Abstract
The present invention relates to a two-way multi-channel artificial cochlea system with an on-chip signal processor, which belongs to the field of the electronic information technology and the medical appliance. The system is composed of an external circuit, an internal circuit and an electrode set, wherein the external circuit is used for acquiring sound signals and transmitting the sound signals which are amplified and modulated to the internal circuit, and providing a computer interface for programming and measuring the internal circuit at the same time; baseband signals are demodulated from the received modulated signals and are digitized by the internal circuit, the demodulated signals are processed by a built-in digital signal processor, so that the output of the electrode set can be controlled to program on line or provide reversal measuring results. The system integrates the digital signal processor with low power consumption on the internal circuit, so that the external circuit only needs to transmits untreated narrow-band analog voice signals to the internal circuit, the limitation of wireless transmission bandwidth is eliminated, and the precision of internal data processing is enhanced; in addition, the system has the capability of remote update and upgrade.
Description
Technical field
The present invention relates to a kind of two-way multi-channel artificial cochlea system that has on-chip signal processor, belong to electronic information technology and medical instruments field.
Background technology
Medically be referred to as the threshold of audibility complete deafness the patient more than 90 decibels.The complete deafness reason of most of patient is the damage rather than the acous deterioration of hair cell.The artificial cochlea is a kind of medical electronics that is used for the treatment of the sensitivities deafness, its function is to replace the hair cell of pathological changes to finish the conversion of sound-electricity, with the remaining acoustic nerve of the stimulating electrical signal that has acoustic information, make the patient produce real auditory perception, thereby reach the purpose of recovering patient's audition.The speech processor of current artificial cochlea system generally adopts the frequency decomposition algorithm, relies on extracorporeal circuit to finish the digitized of the sound signal of telecommunication, decompose and pass to the body internal circuit with wireless mode again after filtering is also encoded.Because electrode number is big, the stimulus frequency height, institute's data quantity transmitted is often very big, need take massive band width (usually in hundred KHz even MHz magnitude), under the limited situation of carrier frequency, must cause data precision deficiency and energy transmission efficiency low, and then influence the performance of system.
Summary of the invention
The present invention is directed to existing deficiency in the above-mentioned background technology, propose a kind of two-way multi-channel artificial cochlea system of the integrated digital of circuit in vivo signal processor, to reach the purpose that improves system accuracy and reduce power consumption.Under current technical conditions, the digital signal processor of integrated small size, extremely low power dissipation has become possibility in the circuit in vivo.The integrated digital signal processor can move to the decomposition filtering of voice signal and other relevant treatment tasks in the body and finishes in the circuit in vivo, make extracorporeal circuit only need to very narrow (several KHz of body internal circuit transmission bandwidth, the contrast aforementioned system hundreds of KHz even a few MHz) complete analog voice signal, at first eliminate the limited problem of transmission bandwidth, improved data processing precision in the body; Next has improved energy transmission efficiency, has reduced system power dissipation.
The two-way multi-channel artificial cochlea system that has on-chip signal processor that the present invention proposes comprises extracorporeal circuit, the body internal circuit of mutual wireless coupling and the electrode group that links to each other with the body internal circuit:
(1) described extracorporeal circuit comprises sound collection unit, automatic gain control unit, computer interface unit, manipulator, comparator and external antenna, wherein,
Sound collection unit is made up of two mikes, and this sound collection unit is used to gather two-way voice or one road voice and one tunnel noise signal;
Automatic gain control unit is made up of two automatic gain control circuits, and its input links to each other with the outfan of above-mentioned two mikes respectively, and this automatic gain control unit is used to adjust the dynamic range of tut collecting unit output signal;
Computer interface unit is used for being connected of described system and computer;
Manipulator, constitute by transistor and Resistor-Capacitor Unit, two inputs of this manipulator link to each other with two outfans of above-mentioned automatic gain control unit respectively, another input links to each other with the outfan of aforementioned calculation machine interface unit, described manipulator is used for CF signal that the analoging sound signal of above-mentioned automatic gain control unit output or computer instruction are modulated to setting, and carries out power amplification;
Comparator, its input links to each other with the voltage signal output end of said modulator, its outfan links to each other with the input of computer interface unit, and this comparator is used for when reverse the measurement said modulator voltage signal of exporting and the magnitude of voltage that presets being compared and comparative result being fed back to computer;
External antenna, its input links to each other with the modulation signal outfan of said modulator, and this external antenna is used for sending modulated signal to the body internal circuit;
(2) described body internal circuit comprises internal antenna, rectification filtering unit, clock generating unit, demodulator, analog-digital converter, digital signal processor, reverse data output unit, digital to analog converter, voltage-controlled current source group and switch matrix, this body internal circuit is that above-mentioned each circuit unit is integrated in characteristic size is that the area that customizes under the technology of 0.18um is on the special chip of 4mm * 4mm, wherein
Internal antenna is coupled with above-mentioned external antenna, is used to receive the modulation signal that extracorporeal circuit sends over;
Rectification filtering unit, its input links to each other with the outfan of above-mentioned internal antenna, and this rectification filtering unit is used for the modulation signal that receives is carried out extracting the supply voltage of crest voltage as other circuit units in the body behind the rectifying and wave-filtering;
Clock generating unit is used for the clock reference of clocking as the body internal circuit;
Demodulator, its modulation signal input links to each other with the outfan of above-mentioned internal antenna, and its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, and this demodulator is used for the modulation signal that receives is carried out extracting baseband signal after the demodulation;
Analog-digital converter is made up of an A/D changer, and its input end of analog signal links to each other with the outfan of above-mentioned demodulator, and this A/D changer is used for converting the analog baseband signal of above-mentioned demodulator output to digital signal;
Digital signal processor, its clock links to each other with the outfan of above-mentioned clock generating unit and the outfan of above-mentioned A-D converter respectively with the data signal input, its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, this digital signal processor is used for the voice data or the computer instruction of above-mentioned A-D converter output are handled: for acoustical signal, this digital signal processor carries out signal filtering to it, resonance point extract and frequency decomposition after according to the output of result control electrode, for programming instruction, this digital signal processor then enters programming state automatically and the routine data that receives is deposited in inner command memory, for measuring instruction, this digital signal processor is then realized the reverse data measuring operation;
The reverse data output unit, its data input pin links to each other with the outfan of above-mentioned digital signal processor, its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, its outfan links to each other with above-mentioned antenna, this reverse data output unit is used for the pulse that the size of the reverse measurement data that provides according to above-mentioned digital signal processor is exported respective width, and change antenna load as switch with pulse, to the reverse measurement data of extracorporeal circuit transmission;
Digital to analog converter is made of a D/A changer, and its input links to each other with the outfan of above-mentioned digital signal processor, and this D/A changer is used for converting the digital signal of digital signal processor output to analog voltage amount;
The voltage-controlled current source group, its input links to each other with the outfan of above-mentioned digital to analog converter, and this voltage-controlled current source group is used for the voltage of above-mentioned digital to analog converter output is changed into the current value of corresponding size;
Switch matrix, its input links to each other with the outfan of above-mentioned voltage-controlled current source group, its control end links to each other with the outfan of above-mentioned digital signal processor, and described switch matrix is used for the electrode channel that gating will be implemented to stimulate under the control of above-mentioned digital signal processor and exports stimulating current on respective channel;
(3) described electrode group, constitute by one group of silicone rubber electrode that applies with the polytetrafluoroethylene insulating coating, its input links to each other with the switch matrix of above-mentioned body internal circuit, its outfan directly links to each other with acoustic nerve, and this electrode group is used for the output current on the above-mentioned switch matrix respective channel is connected to stimulates acoustic nerve on the acoustic nerve.
The two-way multi-channel artificial cochlea system that has on-chip signal processor that the present invention proposes, the digital signal processor by integrated small volume low watt consumption on the circuit in vivo makes system have data-handling capacity in the powerful body.Extracorporeal circuit only needs to transmit undressed pure arrowband analog voice signal to the body internal circuit thus, has both improved the precision of system, has reduced the energy loss in the wireless transmission process again.This system voice signals sampling rate is more than 8K * 12bit/s, the total SR of the pulse of electrode is more than 1MHz, total power consumption is at (body internal circuit power consumption is below 10mW) below the 20mW, the extracorporeal circuit cumulative volume is at 40mm * 25mm * below the 10mm, shortage in weight 200g, chip area is below 4mm * 4mm in the body, whole system have the precision height, low in energy consumption, volume is little and advantage such as in light weight.In addition, intravital digital signal processor can also load multiple speech processing algorithm, and can add new speech processing algorithm at any time by the remote online programming.
Description of drawings
Fig. 1 is the structured flowchart of extracorporeal circuit among the present invention;
Fig. 2 is the structured flowchart of body internal circuit among the present invention.
The specific embodiment
The two-way multi-channel artificial cochlea system that has on-chip signal processor that the present invention proposes, its structured flowchart as shown in Figure 1.Its extracorporeal circuit comprises: sound collection unit, automatic gain control unit, computer interface unit, manipulator, comparator and external antenna; The body internal circuit comprises: internal antenna, rectification filtering unit, clock generating unit, demodulator, analog-digital converter, digital signal processor, reverse data output unit, digital to analog converter, voltage-controlled current source group and switch matrix; The body internal circuit links to each other with acoustic nerve by the electrode group.
The operation principle of system is as described below.Under the normal operating conditions, the sound collection unit of extracorporeal circuit at first converts tones into analog electrical signal, and after amplifying through automatic gain control unit, manipulator directly is modulated to it antenna output; Under programming or the measurement state, what manipulator was imported then is the instruction data, is provided by computer interface by computer, is modulated to antenna output with simulated mode equally, and comparator then detects modularot output voltage to obtain reverse measurement data.The signal that internal antenna is received is at first delivered to rectification filtering unit and is extracted the required supply voltage of body internal circuit work, the required clock reference of body internal circuit is then provided by clock generating unit, meanwhile demodulator recovers baseband signal from the modulation signal of receiving, give digital signal processor after converting digital signal to through analog-digital converter again, digital signal processor is handled accordingly to data of different types: for voice data, need finish signal filtering, computings such as resonance point extraction and frequency decomposition, result is sent to and converts aanalogvoltage on the digital to analog converter to, convert electric current to by the voltage-controlled current source group then, switch matrix is received electric current under the control of digital signal processor stimulates acoustic nerve on the corresponding electrode; For programming instruction, digital signal processor then enters programming state automatically, and the routine data that receives is deposited in the inner program storage; For measuring instruction, then measurement result is delivered to the reverse data output unit, change antenna load by this unit measurement data is passed to extracorporeal circuit.
Among the embodiment of this scheme, the model of mike is EM-100B in the sound collection unit, the model of automatic gain control unit is MAX4252, the model of comparator is MAX987, the control circuit that manipulator is made up of modulation transistor, Resistor-Capacitor Unit and some logic circuits constitutes, computer interface adopts RS-232 interface, antenna is made of a pair of inductance coil, it is that the area that customizes under the 0.18um technology is on the special chip of 4mm * 4mm that the body internal circuit all is integrated in characteristic size, and the electrode group is made of 17 silicone rubber electrodes that apply with the polytetrafluoroethylene insulating coating.Whole system adopts complete 3.6 volts of power supplys design, with one 3.6 volts lithium rechargeable batteries or three joint Ni-MH battery power supplies, uses low pressure difference linear voltage regulator output 3.3V and 1.8V running voltage.Body internal circuit and electrode group are implanted patient's cochlea, and external antenna places the patient to be coupled with internal antenna in one's ear, and extracorporeal circuit (except that antenna) then is encapsulated in size in the box of 40mm * 25mm * 10mm, and link to each other with external antenna by lead.The patient can carry box-packed extracorporeal circuit, and can place any position of health.
Claims (1)
1, a kind of two-way multi-channel artificial cochlea system that has on-chip signal processor is characterized in that this system comprises extracorporeal circuit, the body internal circuit of mutual wireless coupling and the electrode group that links to each other with the body internal circuit:
(1) described extracorporeal circuit comprises sound collection unit, automatic gain control unit, computer interface unit, manipulator, comparator and external antenna, wherein,
Sound collection unit is made up of two mikes, and this sound collection unit is used to gather two-way voice or one road voice and one tunnel noise signal;
Automatic gain control unit is made up of two automatic gain control circuits, and its input links to each other with the outfan of above-mentioned two mikes respectively, and this automatic gain control unit is used to adjust the dynamic range of tut collecting unit output signal;
Computer interface unit is used for being connected of described system and computer;
Manipulator, constitute by transistor and Resistor-Capacitor Unit, two inputs of this manipulator link to each other with two outfans of above-mentioned automatic gain control unit respectively, another input links to each other with the outfan of aforementioned calculation machine interface unit, described manipulator is used for CF signal that the analoging sound signal of above-mentioned automatic gain control unit output or computer instruction are modulated to setting, and carries out power amplification;
Comparator, its input links to each other with the voltage signal output end of said modulator, its outfan links to each other with the input of computer interface unit, and this comparator is used for when reverse the measurement said modulator voltage signal of exporting and the magnitude of voltage that presets being compared and comparative result being fed back to computer;
External antenna, its input links to each other with the modulation signal outfan of said modulator, and this external antenna is used for sending modulated signal to the body internal circuit;
(2) described body internal circuit comprises internal antenna, rectification filtering unit, clock generating unit, demodulator, analog-digital converter, digital signal processor, reverse data output unit, digital to analog converter, voltage-controlled current source group and switch matrix, this body internal circuit is that above-mentioned each circuit unit is integrated in characteristic size is that the area that customizes under the technology of 0.18um is on the special chip of 4mm * 4mm, wherein
Internal antenna is coupled with above-mentioned external antenna, is used to receive the modulation signal that extracorporeal circuit sends over;
Rectification filtering unit, its input links to each other with the outfan of above-mentioned internal antenna, and this rectification filtering unit is used for the modulation signal that receives is carried out extracting the supply voltage of crest voltage as other circuit units in the body behind the rectifying and wave-filtering;
Clock generating unit is used for the clock reference of clocking as the body internal circuit;
Demodulator, its modulation signal input links to each other with the outfan of above-mentioned internal antenna, and its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, and this demodulator is used for the modulation signal that receives is carried out extracting baseband signal after the demodulation;
Analog-digital converter is made up of an A/D changer, and its input end of analog signal links to each other with the outfan of above-mentioned demodulator, and this A/D changer is used for converting the analog baseband signal of above-mentioned demodulator output to digital signal;
Digital signal processor, its clock links to each other with the outfan of above-mentioned clock generating unit and the outfan of above-mentioned A-D converter respectively with the data signal input, its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, this digital signal processor is used for the voice data or the computer instruction of above-mentioned A-D converter output are handled: for acoustical signal, this digital signal processor carries out signal filtering to it, resonance point extract and frequency decomposition after according to the output of result control electrode, for programming instruction, this digital signal processor then enters programming state automatically and the routine data that receives is deposited in inner command memory, for measuring instruction, this digital signal processor is then realized the reverse data measuring operation;
The reverse data output unit, its data input pin links to each other with the outfan of above-mentioned digital signal processor, its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, its outfan links to each other with above-mentioned antenna, this reverse data output unit is used for the pulse that the size of the reverse measurement data that provides according to above-mentioned digital signal processor is exported respective width, and change antenna load as switch with pulse, to the reverse measurement data of extracorporeal circuit transmission;
Digital to analog converter is made of a D/A changer, and its input links to each other with the outfan of above-mentioned digital signal processor, and this D/A changer is used for converting the digital signal of digital signal processor output to analog voltage amount;
The voltage-controlled current source group, its input links to each other with the outfan of above-mentioned digital to analog converter, and this voltage-controlled current source group is used for the voltage of above-mentioned digital to analog converter output is changed into the current value of corresponding size;
Switch matrix, its input links to each other with the outfan of above-mentioned voltage-controlled current source group, its control end links to each other with the outfan of above-mentioned digital signal processor, and described switch matrix is used for the electrode channel that gating will be implemented to stimulate under the control of above-mentioned digital signal processor and exports stimulating current on respective channel;
(3) described electrode group, constitute by one group of silicone rubber electrode that applies with the polytetrafluoroethylene insulating coating, its input links to each other with the switch matrix of above-mentioned body internal circuit, its outfan directly links to each other with acoustic nerve, and this electrode group is used for the output current on the above-mentioned switch matrix respective channel is connected to stimulates acoustic nerve on the acoustic nerve.
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| CN110850773A (en) * | 2019-11-14 | 2020-02-28 | 北京和利时系统工程有限公司 | Signal acquisition method and device, computer storage medium and electronic equipment |
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| CN100517908C (en) * | 2007-06-21 | 2009-07-22 | 清华大学 | Power-supplying circuit with zero-static consumption induction controlled |
| DK2280560T3 (en) * | 2009-07-03 | 2015-12-14 | Bernafon Ag | Hearing aid system comprising a receiver in the ear and a system for identifying the receiver type |
| CN103142328B (en) * | 2013-02-07 | 2015-01-21 | 浙江诺尔康神经电子科技股份有限公司 | Speech processor capable of performing multi-channel dynamic range adjustment for electrical cochlea and method |
| CN103190965B (en) * | 2013-02-28 | 2015-03-11 | 浙江诺尔康神经电子科技股份有限公司 | Voice-endpoint-detection based artificial cochlea automatic gain control method and system |
| CN103156709B (en) * | 2013-04-09 | 2015-01-21 | 上海力声特医学科技有限公司 | Method for reducing electrical cochlea power consumption |
| BR102015016843A2 (en) * | 2015-06-17 | 2016-02-02 | Medtronic Inc | implantable medical device |
| CN105434084A (en) * | 2015-12-11 | 2016-03-30 | 深圳大学 | Mobile equipment, extracorporeal machine, artificial cochlea system and speech processing method |
| CN105488987B (en) * | 2016-01-19 | 2018-12-28 | 东南大学 | A kind of passive and wireless micro-machinery switch array control system |
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| US6161046A (en) * | 1996-04-09 | 2000-12-12 | Maniglia; Anthony J. | Totally implantable cochlear implant for improvement of partial and total sensorineural hearing loss |
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