CN100336486C - Synchronous analyzer for detecting signal of blood stream from nystagmus image and ear ending - Google Patents
Synchronous analyzer for detecting signal of blood stream from nystagmus image and ear ending Download PDFInfo
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- CN100336486C CN100336486C CNB2005100418437A CN200510041843A CN100336486C CN 100336486 C CN100336486 C CN 100336486C CN B2005100418437 A CNB2005100418437 A CN B2005100418437A CN 200510041843 A CN200510041843 A CN 200510041843A CN 100336486 C CN100336486 C CN 100336486C
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Abstract
The present invention discloses a synchronous detection analyzer for nystagmus pictures and aurisdistal blood stream signals, which can synchronously obtain the signal analysis relevant to vertigo or the signal analysis of changed nystagmus and aurisdistal blood flow which is not caused by vertigo. The present invention is composed of a light sheltering eye mask (8), a weak light source (11), a CCD sensor (9), a raster (10), an infrared emission light source (4), an infrared light detector (2), a signal acquisition card, a computer, a display and a printer, wherein nystagmus signals are acquired by the CCD sensor (9), the raster (10) and the signal acquisition card; aurisdistal blood flow signals are acquired by the infrared emission light source (4), the infrared light detector (2) and the signal acquisition card; output signals processed by the computer can be transmitted to a supervisory computer or can be exchanged with signals of the supervisory computer or can be displayed and printed. The present invention can detect without wound and can synchronously collect signals of nystagmus and aurisdistal blood flow. The present invention provides reliable judging bases for clinical diagnosis and pharmacology analysis.
Description
Technical field
The present invention relates to a kind of Electronystagmogram, ear ending blood flow signal synchronous analyzer for detecting, but synchronous detecting nystagmus figure and ear ending blood flow signal.
Background technology
Usually, nystagmus is relevant with multiple physiological change, as vertebra-basilar artery insufficiency, motion sexually transmitted disease (STD), mental sickness, and especially dizzy disease.Dizzyly not only nystagmus can be caused, and the autonomic nervous dysfunction can be caused.Nervous dysfunction can cause that the ear ending vasoconstriction causes green around the gills.Because the tip blood of ear is to be carried by face's blood vessel, green around the gills is that ear ending exists the degree of blood supply insufficiency and dizzy degree that necessary relation is arranged because of due to the tip blood supply insufficiency of ear when then dizzy.Therefore the change information that obtains Electronystagmogram information and ear ending blood flow can be analyzed dizzy degree and analyze the dizzy reason that causes.
Dizzy mechanism: normal spatial relationship is meant that parts of body is in antigravity optimum balance state, is meant that body gesture plays an important role in the balance adjustment of health with correct " balance three " with stable.Balance three: by forming of quiet-moving system's (vestibule-labyrinthine system) vision and somesthetic sensibility (sense of touch and depth perception).The basic organ of position to sensation takes place in vision, somesthetic sensibility and vestibular sensations system, the orientation of object on every side is familiar with in visual experience, and the relation of and external object own, because the conduction of somesthetic sensibility makes man-hour carve scope, the amplitude of attitude, position and the motion of understanding self constantly; The travel direction that the people can distinguish limbs of experiencing owing to vestibular apparatus, in a single day the center of gravity of judging body shifts, motion has taken place limbs, variation has just taken place in balance immediately, so the sensory organ of vision somesthetic sensibility, vestibule static sense imports signal into nervus centralis immediately, in reticular formation of brain stem, integrate, three's sensation impulsion coordination nothing is contrary to, is produced normal position to experience.Variation has taken place in the sensory function at three positions, all may cause dizzy.
Dizzy generation mechanism: the activity of vestibular system seldom is people's perception under the normal condition, when be subjected to bigger stimulation and when damage, vestibular apparatus and from the proprioception organ in muscle, joint to the inconsistent generation motor hallucination of spatial orientation impulse response, promptly dizzy.Second kind of situation causes that afferent impulse imbalance in both sides produces dizzy sensation at cerebral cortex when being side vestibular nerve damage.The third situation is vestibule-eye reflex obstacle, and vestibular nucleus is by medial longitudinal fasciculus and moving eye, and coaster and nucleus of abducent nerve interrelate, the impaired nystagmus that occurs of this path.The 4th kind of situation is that vestibular nucleus is got in touch formation vestibule spinal cord path by vestibulospinal tract and cerebellum, rubrum, ventricornu cell, and vestibulospinal reflex produces disequilibrium and coordinate movement imbalance unusually.The 5th be deeply in love vasomotor center that condition is vestibular nucleus and reticular formation of brain stem, vagus nerve nucleus etc. get in touch not normal, when the vestibule delayed ischemic neurological deficits.The 6th kind of situation is that vestibule semicircular duct sensation is responsive, and when rectilinear motion and rotation variable motion, afferent impulse causes strong reaction, causes posture insufficiency of accommodation and dizzy.The 7th kind of situation is the relevant blood supply of getting lost with its influence with vasomotion of orthosympathetic fiber (syndrome when belonging to psychentonia and anxiety) that is wrapped on the vasa labyrinthi wall.
The dizzy cause of disease: cause according to statistics the dizzy cause of disease have 80 surplus kind, the cause of disease that has is clear and definite, but also has 30%～40% still difficultly to determine [Chen Xuetao, the dizzy cause of disease, clinical manifestation and classification, Chinese rural medical magazine, 2003,10 (3)].The dizzy medical inspection method commonly used of dizzy diagnosis and symptom Differential Diagnosis thereof mainly contains following several.
Examination of ocular fundus: check papilloedema, check optical fundus blood vessel, check retina.
Otoneurology is checked: check audition, Eustachian tube, semicircular duct and otolith function.
Check biochemical indicator: hematocrit, blood viscosity, fibronectin, erythrocyte rigidity, platelet count, adhesiveness and clustering etc.
Image and physical examination: inner ear labyrinth, the superelevation electron beam scanning, colorful ultrasonic scanning and the multispectral blood flow analysis instrument of reining in are checked the entocranial artery blood flow.
Electrophysiologic study: check electric audiometry, auditory evoked potential, electronystagmogram etc. [Li Yingxi, the explanation of dizzy clinical diagnosis and the suggestion of treatment flow process, Chinese neuropsychiatric disease magazine, 2003,29 (4)].
By Electronystagmogram vertebra base tremulous pulse blood supply insufficiency dizzy measured nystagmus occurrence rate 87%[and open forever post etc., the meaning of electronystagmogram diagnosis megrim caused by vertebra-fundus artery blood supply insufficiency, Chinese clinical rehabilitation, 2002,21 (6)].
Other has internal ear temperature-sensitive stimulation test: internal ear temperature-sensitive stimulation test is inhomogeneously can cause dizzy and nystagmus because the lymph fluid in the semicircular duct is heated.
Rotation test: can cause that semicircular duct is subjected to inertia effects to produce sense of rotation and nystagmus.
Position experiment: produce dizzy and nystagmus [stone advances, dizzy general diagnostic order, Chinese rural medical magazine, 2003,10 (3)] because experimenter's head place diverse location causes the moment dynamic change of semicircular duct lymph fluid.
People such as Guo Chunmiao adopt TCD to analyze 70 routine dizzy persons and provide diagnosis basis for 57 routine vertebra base tremulous pulse blood supply insufficiencies, adopt French explorer-cvs detector artery and under different depth, detect substrate bilateral vertebral artery and posterior inferior cerebellar artery in different depth is surveyed before left and right sides temporo window detects the homonymy brain respectively through the big empty window of occipital bone, measure the contraction of blood vessel, diastole mean blood flow velocity and vascular pulsation index, measure the slack-off [people such as Guo Chunmiao of dizzy person's blood flow rate, TCD (colored multispectral reining in) detects the diagnostic value to VBI (vertebra base tremulous pulse blood supply insufficiency) vertigo, the new medical science of China, 2002,3 (1)].
Belong to different generation reasons by distinguishing different nystagmus axial amplitude to the feature analysis of nystagmus, the Meniere's disease nystagmus is horizontal movement, the nystagmus of psychosis and other disease has its feature [yellow maidenliness etc. respectively, nystagmus is observed the meaning in the patients with vertigo nursing, the nurse studies magazine, 2003,18 (3)].
The above-mentioned nystagmus that studies show that quivers and with dizzy close ties is arranged, nystagmus quivers also has multiple disease to cause, the different nystagmus feature of quivering is caused by different reasons, the nystagmus that has quivers and does not contact directly with dizzy, dizzy have multiple reason to cause, the correct diagnosis of dizzy reason is very important to treatment, the dizzy autonomic nervous dysfunction who causes causes that peripheral vessel shrinks the not all nystagmus of disease reason cause ear ending blood vessel ischemia to belong to some type syndrome that quivers, and the feature of analyzing nystagmus changes analyzing the nystagmus and the vertigo cause of disease significant in conjunction with ear ending blood vessel ischemia.
Though existing medical inspection has a several different methods to dizzy, also adopt multiple inspection method to be added on analysis to the dizzy reason that causes usually in clinical to reach the purpose of correct diagnosis.But, the diagnostic instruments that obtains the foundation of mutual confirmation an analytical tool does not appear in the newspapers as yet, adopt the instrument can same at one time place, the information that the synchronous detecting nystagmus quivers, ear ending blood vessel ischemia changes can be avoided the interference of time difference and environment change.
Summary of the invention
In order to overcome the deficiency that prior art can not detect the information that nystagmus quivers, ear ending blood vessel ischemia changes simultaneously, the invention provides a kind of Electronystagmogram, ear ending blood flow signal synchronous analyzer for detecting, but synchronous detecting nystagmus figure and ear ending blood flow signal.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Electronystagmogram, ear ending blood flow signal synchronous analyzer for detecting, comprise ear ending blood flow signal deriving means, nystagmus quiver signal deriving means, data acquisition card, computer, display and printer, it is characterized in that: the quiver signal of signal deriving means collection of ear ending blood flow signal deriving means and nystagmus is input to computer by data acquisition card.
Described ear ending blood flow signal deriving means comprises infrared emission light source 4 and infrared detector 2, and infrared emission light source 4 and infrared detector 2 and ear tissue 1 are separated by that a formula is placed and in opposite directions and right.
The described nystagmus signal deriving means that quivers comprises ccd sensor 9, grating 10 and low-light source 11, and low-light source 11 is installed in the bottom of lucifuge eyeshield 8, between low-light source 11 and ccd sensor 9 grating 10 is installed.
Described grating 10 is installed for level.
The invention has the beneficial effects as follows: because ear ending blood flow signal deriving means and the nystagmus signal deriving means that quivers is electrically connected with data acquisition card respectively, but the noinvasive triage is surveyed, but and synchronous detecting nystagmus figure and ear ending blood flow signal, for clinical diagnosis and pharmacology analysis improve reliable basis for estimation.
The present invention is further described below in conjunction with drawings and Examples.
Description of drawings
Fig. 1 is an ear ending blood flow signal deriving means occupation mode front view of the present invention;
Fig. 2 is an ear ending blood flow signal deriving means occupation mode rear view of the present invention;
Fig. 3 is ear ending blood flow signal deriving means infrared transmitter of the present invention and infrared detector location view;
Fig. 4 is the nystagmus of the present invention signal deriving means view that quivers;
Fig. 5 is a structured flowchart of the present invention;
Fig. 6 is the quiver stop position sketch map of signal deriving means of nystagmus of the present invention.
The specific embodiment
According to the dizzy nystagmus that causes, cause the autonomic nervous dysfunction with dizzy, thereby the peripheral vessel spasm that causes face causes face's tip blood supply insufficiency, the clinical symptoms of ear ending blood supply insufficiency, the present invention is by low-light emission directive eyeball surface, form hot spot-promptly form dancing hot spot when the nystagmus hot spot on the surface of eyeball, the hot spot of beating adopts video camera (CCD) to obtain nystagmic image, and by grating device with nystagmic kinematic axis to differentiating nystagmus horizontal vibration amplitude or vertical amplitude, or unordered trembling, grating device is a horizontal grate, hot spot is beated and is horizontal continuous wave figure when the nystagmus horizontal vibration amplitude, when the nystagmus vertical amplitude because grating device is cut into breakpoint ripple figure for the horizontal grate hot spot seriality of beating by horizontal grate, by the ccd signal collection, Computer Processing calculates frequency, amplitude, the identification nystagmus is vertical amplitude or horizontal vibration amplitude, ear ending blood flow velocity flow signal is to be surveyed by Infrared Detectors by ear tissue by infrared emission light, the ear ending blood engorgement is different with ear ending ischemia infrared Absorption amount, Infrared Detectors obtains the information of variation, the change information that Infrared Detectors obtains inputs to computer, is calculated the changing value of ear ending blood flow velocity flow by Computer Processing.
With reference to Fig. 1～6.Form ear ending blood flow signal deriving means by the 3600Hz modulation circuit that infrared emission light source 4 infrared detectors 2 leads 3 are formed, infrared emission light is surveyed by Infrared Detectors by ear tissue, infrared emission light source 4 is through modulation 3600Hz, the light source of emission passes ear tissue 1 and is received by infrared detector 2, because the peripheral vessel blood flow difference that ear tissue 1 distributes is also different to the light source amount of being absorbed of passing ear tissue 1, infrared detector 2 receiving optical signals change with the light source amount of being absorbed is different, the signal of infrared detector 2 outputs also changes with the light source amount of being absorbed is different, the signal of infrared detector 2 outputs exports the capture card collection to through lead 3 and imports computer again, and machine is handled output demonstration or output print as calculated.
Form the nystagmus signal deriving means that quivers by lucifuge eyeshield 8, low-light source 11, CCD9 and grating 10, lucifuge eyeshield 8 covers eyeball 7 and avoids interference light source, and the bottom of lucifuge eyeshield 8 is equipped with low-light source 11.Grating 10 is installed between low-light source 11 and the CCD9, and grating 10 is installed for level.Eyeball 7 showed the low-light speckle when low-light source 11 covered eyeball 7 at lucifuge eyeshield 8, eyeball 7 and CCD9 light path coaxial, and the low-light speckle is absorbed by CCD9, and the low-light speckle signal of picked-up is through data acquisition card collection input computer, and machine is handled to export and is shown or output print as calculated.
The same at one time place of Electronystagmogram ear ending blood flow signal obtains, the interference of having avoided time difference and place and environment to change, and the signal that Electronystagmogram ear ending blood flow synchronous detecting obtains is used for medical diagnosis on disease and the pharmacological evaluation analysis has great importance.
Claims (4)
1, a kind of Electronystagmogram, ear ending blood flow signal synchronous analyzer for detecting, comprise ear ending blood flow signal deriving means, nystagmus quiver signal deriving means, data acquisition card, computer, display and printer, it is characterized in that: the quiver signal of signal deriving means collection of ear ending blood flow signal deriving means and nystagmus is input to computer by data acquisition card.
2, Electronystagmogram according to claim 1, ear ending blood flow signal synchronous analyzer for detecting, it is characterized in that: described ear ending blood flow signal deriving means comprises infrared emission light source (4) and infrared detector (2), and infrared emission light source (4) and infrared detector (2) and ear tissue (1) are separated by that a formula is placed and in opposite directions and right.
3, Electronystagmogram according to claim 1, ear ending blood flow signal synchronous analyzer for detecting, it is characterized in that: the described nystagmus signal deriving means that quivers comprises ccd sensor (9), grating (10) and low-light source (11), low-light source (11) is installed in the bottom of lucifuge eyeshield (8), between low-light source (11) and ccd sensor (9) grating (10) is installed.
4, Electronystagmogram according to claim 3, ear ending blood flow signal synchronous analyzer for detecting is characterized in that: described grating (10) is installed for level.
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2005100418437A CN100336486C (en) | 2005-03-23 | 2005-03-23 | Synchronous analyzer for detecting signal of blood stream from nystagmus image and ear ending |
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| CNB2005100418437A CN100336486C (en) | 2005-03-23 | 2005-03-23 | Synchronous analyzer for detecting signal of blood stream from nystagmus image and ear ending |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20110176106A1 (en) * | 2006-05-01 | 2011-07-21 | Christopher Paul Lewkowski | Portable eye monitoring device and methods for using the same |
| CN104146684B (en) * | 2014-06-25 | 2016-03-30 | 兰州大学 | The dizzy detector of a kind of eyeshield formula |
| EP3991642A1 (en) * | 2015-03-30 | 2022-05-04 | Natus Medical Incorporated | Vestibular testing apparatus |
| US10426379B2 (en) | 2015-03-30 | 2019-10-01 | Natus Medical Incorporated | Vestibular testing apparatus |
| CN111191639B (en) * | 2020-03-12 | 2024-03-08 | 上海志听医疗科技有限公司 | Vertigo type identification method and device based on eye shake, medium and electronic equipment |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6144867A (en) * | 1998-09-18 | 2000-11-07 | The United States Of America As Represented By The Secretary Of The Army | Self-piercing pulse oximeter sensor assembly |
| US20040097839A1 (en) * | 2002-07-03 | 2004-05-20 | Epley Research, L.L.C. | Head-stabilized medical apparatus, system and methodology |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6144867A (en) * | 1998-09-18 | 2000-11-07 | The United States Of America As Represented By The Secretary Of The Army | Self-piercing pulse oximeter sensor assembly |
| US20040097839A1 (en) * | 2002-07-03 | 2004-05-20 | Epley Research, L.L.C. | Head-stabilized medical apparatus, system and methodology |
Non-Patent Citations (1)
| Title |
|---|
| 经颅超声多普勒对眩晕的病因诊断 刘新良，中国航天医药杂志，第4卷第4期 2002 * |
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