CL2017001466A1 - A process for the manufacture of idalopirdine - Google Patents

A process for the manufacture of idalopirdine

Info

Publication number
CL2017001466A1
CL2017001466A1 CL2017001466A CL2017001466A CL2017001466A1 CL 2017001466 A1 CL2017001466 A1 CL 2017001466A1 CL 2017001466 A CL2017001466 A CL 2017001466A CL 2017001466 A CL2017001466 A CL 2017001466A CL 2017001466 A1 CL2017001466 A1 CL 2017001466A1
Authority
CL
Chile
Prior art keywords
idalopirdine
manufacture
idalopiridine
preparation
pharmaceutically acceptable
Prior art date
Application number
CL2017001466A
Other languages
Spanish (es)
Inventor
Mikkel Fog Jacobsen
Ole Nielsen
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of CL2017001466A1 publication Critical patent/CL2017001466A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

<p>EN LA PRESENTE SE DESCRIBE UN PROCESO PARA LA PREPARACIÓN DE IDALOPIRIDINA Y SALES FARMACÉUTICAMENTE ACEPTABLES DE ESTA.</p><p> A PROCESS FOR THE PREPARATION OF IDALOPIRIDINE AND PHARMACEUTICALLY ACCEPTABLE SALTS OF THIS IS DESCRIBED. </p>

CL2017001466A 2014-12-12 2017-06-08 A process for the manufacture of idalopirdine CL2017001466A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA201400721 2014-12-12

Publications (1)

Publication Number Publication Date
CL2017001466A1 true CL2017001466A1 (en) 2018-01-05

Family

ID=59011415

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017001466A CL2017001466A1 (en) 2014-12-12 2017-06-08 A process for the manufacture of idalopirdine

Country Status (13)

Country Link
EP (1) EP3230265A1 (en)
JP (1) JP2017537128A (en)
KR (1) KR20170093821A (en)
CN (1) CN107001266A (en)
AU (1) AU2015359347A1 (en)
BR (1) BR112017012021A2 (en)
CA (1) CA2968770A1 (en)
CL (1) CL2017001466A1 (en)
CO (1) CO2017005357A2 (en)
IL (1) IL252471A0 (en)
MA (1) MA41148A (en)
MX (1) MX2017007510A (en)
RU (1) RU2017120216A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10196363B2 (en) 2014-12-12 2019-02-05 Japan Tobacco Inc. Dihydropyrimidin-2-one compounds and medical use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3042685A (en) * 1962-07-03 Process of making g-fluoro tryptamine
AR065804A1 (en) * 2007-03-23 2009-07-01 Smithkline Beecham Corp COMPOSITE OF INDOL CARBOXAMIDE, PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS IT AND USE OF THIS COMPOUND TO PREPARE A MEDICINAL PRODUCT
TW201139370A (en) * 2009-12-23 2011-11-16 Lundbeck & Co As H Processes for the manufacture of a pharmaceutically active agent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10196363B2 (en) 2014-12-12 2019-02-05 Japan Tobacco Inc. Dihydropyrimidin-2-one compounds and medical use thereof

Also Published As

Publication number Publication date
AU2015359347A1 (en) 2017-06-08
IL252471A0 (en) 2017-07-31
CN107001266A (en) 2017-08-01
CO2017005357A2 (en) 2017-09-20
EP3230265A1 (en) 2017-10-18
CA2968770A1 (en) 2016-06-16
RU2017120216A (en) 2019-01-15
BR112017012021A2 (en) 2018-03-13
KR20170093821A (en) 2017-08-16
JP2017537128A (en) 2017-12-14
MA41148A (en) 2017-10-17
MX2017007510A (en) 2017-08-22

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