CH713377A2 - Cannula insertion mechanism for a patch device. - Google Patents

Abstract

A reciprocating drive for an insertion mechanism for a delivery device having a planar or domed base (2a) and a guideway (2h) formed in or on the base defining a proximal and a distal end and a straight line or curve therebetween. Furthermore, the drive comprises a drive track (2b) connected to the base, comprising a plurality of drive sections, wherein a first drive section (2c) and a second drive section (2d) are opposite each other and parallel to the straight line or to the curve of the guide track. A carriage (6) is rotationally fixed to the base (2a) and slidable along or in the guideway (2h) between a proximal carriage end position and a distal carriage end position. A drive wheel (4) is at least rotatably mounted in the carriage and a torque source (5) is connected between carriage (6) and drive wheel (4) through which the drive wheel (4) relative to the base (2a) and carriage (6) in rotation is displaceable. With rotation of the drive wheel (4), the slide (6), starting from in particular the proximal Schlittenendposition by a positive or non-positive engagement of the drive wheel (4) in the first drive section (2c) along or in the guideway (2h) moves in the distal direction in that, at the distal end of the first drive section (2c), the positive or non-positive engagement of the drive wheel from the first (2c) to the second drive section (2d) is changed by further rotation of the drive wheel (4) and the carriage (6) consequently moves along or in the guideway (2h) shifts in the proximal direction until, for example, stops, in particular the proximal end of the guideway, the carriage (6) and the rotation of the drive wheel (4), in particular in the proximal Schlittenendposition stops.

Description

description

Technical field The invention relates to injection and infusion devices, in particular injection and infusion devices, which are applied, in particular glued, for the administration of a substance directly to the skin of the person using it, which are also known as patch devices. In particular, the invention relates to mechanisms for insertion of cannulas, in particular so-called soft cannulas, which are made for example of fluoropolymers (such as polytetrafluoroethylene) or property-like materials.

General Description A delivery device for fluid products, in particular an infusion pump or an injection device, in particular a patch infusion pump or a patch injector, may in principle be suitable for the administration of a wide variety of medicaments, provided that the medicament has a consistency which corresponds to the infusion pump or the injection device can be distributed. However, the aforementioned consistency, meaning for example the viscosity, may make it reasonable to optimize the design of the injection device or the infusion pump in order to make the use of the medicament as pleasant as possible for the user. One possibility for such optimization is the use of so-called patch devices (patch infusion pump, especially in the treatment of diabetes with insulin, or patch injectors, especially administration of high viscosity antibody formulations). The devices are stuck by means of plaster directly on the body of the user and then no longer need to be held manually or stowed for example in a holster.

As used herein, the term "medicament" includes any fluid medical formulation suitable for controlled administration by an agent, such as e.g. a cannula or hollow needle, for example comprising a liquid, a solution, a gel, an emulsion or a fine suspension containing one or more medicinal agents. "Drug" may be a single drug composition or a premixed or co-formulated multi-drug composition from a single container. Drug includes drugs such as peptides (eg, insulins, insulin-containing drugs, GLP-1 containing as well as derived or analogous preparations), proteins and hormones, biologically derived or active agents, hormone or gene based drugs, nutritional formulas, enzymes, and other substances both in the art solid (suspended) or liquid form but also polysaccharides, vaccines, DNA or RNA or oligonucleotides, antibodies or parts of antibodies and suitable base, excipients and carriers.

Patch devices in the sense of the present application, ie patch infusion pumps or patch injectors, often include so-called (cannula) insertion mechanisms, which serve to introduce a cannula into the tissue of the person using it. Some of these patch devices use soft infusion cannulas made of plastic, especially biocompatible fluoropolymers, for the delivery of the fluid medicament. This has the advantage that the soft infusion cannula potentially causes less pain to the user using the surrounding tissue than an infusion cannula made of a rigid material such as steel. Another advantage of the soft infusion cannulae is that it can not break with soft cannulas. In order to be able to insert a soft infusion cannula into the tissue at all, an insertion cannula (or an insertion needle) made of a rigid material such as steel is used. This insertion cannula is passed through the infusion cannula prior to insertion of the infusion cannula and protrudes beyond the open end of the infusion cannula. The insertion cannula is inserted into the tissue together with the infusion cannula during insertion. When the infusion cannula has reached its final position in the tissue, the insertion cannula is withdrawn. Only the soft infusion cannula remains in the tissue.

In some insertion mechanisms, the inner lumen of the insertion cannula is part of the fluid path through which the fluid medicament is administered. In this case, the insertion cannula in the retraction described above is not completely pulled out of the infusion cannula, so that the fluid to be administered drug is passed from the insertion cannula into the infusion cannula and from there via one or more openings of the infusion cannula into the tissue of the person using.

From US 7 128 727 B2 a patch infusion pump 10 with an insertion mechanism is known, with which a soft infusion cannula 38 is introduced by means of an insertion cannula 62 into the tissue. The mechanism described uses for the insertion movement of the infusion cannula and the subsequent withdrawal of the insertion cannula separate springs 70 resp. 82, so at least one spring 70, which provides the energy for the insertion movement and at least one spring 82, which provides the energy for the return movement.

From the US 2014 142 508 A1 a patch infusion pump 100 with insertion mechanism is known, with which a soft infusion cannula 176 is introduced by means of an insertion cannula 174 into the tissue. The drive of the insertion mechanism is realized with a torsion spring 181. In this case, the drive spring 181 is connected to a slide 184 via an arm system 183a, 183b. The two partial arms 183a and 183b are connected to each other via a hinge, so that the two partial arms 183a, 183b are rotatable in a plane relative to each other. The disclosed insertion mechanism allows the execution of the insertion movement and the withdrawal movement with a spring 181.

It is an object of the invention to provide drives for alternative cannula insertion mechanisms, as well as alternative cannula insertion mechanisms for delivery devices, particularly patch devices such as patch infusion pumps or patch injectors, which are inexpensive to manufacture while maintaining high reliability.

The object is achieved according to the independent claim 1, advantageous developments emerge from the dependent claims, the description and the figures.

In the following description, the terms distal and proximal with respect to position and direction indications are used. Distal means from the point of view of the fluid path of the administering device to the person using and proximal corresponding to the reverse. For example, the movement of an infusion cannula, which is introduced into the tissue of the person using it, is a movement in the distal direction, also referred to below as insertion direction.

One aspect of the invention includes a cannulation mechanism for a patch device, in particular a patch infusion pump or a patch injector. In the following description will be discussed in particular insertion mechanisms for patch infusion pumps, but which can be used in the same form for patch injectors, or could be used in other delivery devices without departing from the invention.

In one aspect of the invention, the patch infusion pump comprises a housing. The housing may be constructed in one or more parts and comprises a so-called base, which represents the region of the housing which is arranged on the skin of the user using plaster. The base itself can be designed in several parts and can also include inserts, such as in particular guide elements, which are mounted at the Monday at the base.

In one aspect of the invention, the patch infusion pump comprises an insertion mechanism for placing a flexible or soft infusion cannula in tissue of the person using it. The flexible or soft infusion cannula is introduced into the tissue with the aid of an insertion cannula.

In one aspect of the invention, the insertion mechanism of the patch infusion pump comprises a drive spring, in particular a torsion spring, and a gear, wherein the drive spring can transmit energy to the gear, which thereby can be set in motion, in particular rotation. In an advantageous embodiment, the drive spring is designed as a torsion spring, which may have a helical or spiral shape. Alternatively, the torsion spring could be a torsion bar or a stretched rubber band wound onto an axle. The drive spring can already be biased in the delivery state of the insertion mechanism (ie the patch device). Alternatively, the power spring may be biased prior to use. The person skilled in this relevant methods are known.

In one aspect of the invention, the insertion mechanism comprises a carriage on which the insertion cannula is fixed, wherein the carriage is operatively coupled to the gear, so that a movement, in particular rotation of the gear movement of the carriage and thus the insertion cannula for May have consequences. In the initial state, the infusion cannula is drawn over the insertion cannula, which is deposited in the tissue of the user using the insertion cannula as part of the insertion process. After deposition, the insertion cannula is withdrawn from the tissue through the infusion cannula, leaving the lumens of the two cannulas interconnected so that the medicament can be delivered via the insertion cannula into the infusion cannula and subsequently into the tissue of the user.

In one aspect of the invention, the insertion mechanism of the patch infusion pump comprises a guide slot (advantageously with one or more partial scenes) along which the gear can be guided via serrations or pin arrangements, wherein a rotation of the gear via the guide along the serrations or Pin arrangements can be transformed into a translation of the gear axis relative to the guide slot.

In one aspect of the invention, a plurality of toothings and pin arrangements along the guide slot are arranged so that the gear axis is staggered in time in different directions relative to the guide slot movable.

In one aspect of the invention, the gear is only partially occupied by teeth at its periphery, wherein it can be divided into two sectors, a first sector which is toothed and a second sector in which no teeth are present. In alternative embodiments, the gear could also have more than two sectors, with toothed and untoothed sectors alternating.

In one aspect of the invention, the guide slot comprises a first toothed part raceway and a second toothed part raceway, the first and second part raceways facing each other (antiparallel or mirrored), and the teeth of the first sector of the gearwheel first at the toothing unroll the first part of the track and then roll on the second part of the track on further rotation of the gear in the same direction and the teeth of the first sector are either in engagement with the first part of the gate or the second part of the gate, but not in engagement with both simultaneously. This sequential engagement of the teeth results in this aspect of the invention in that the gear axis moves during the engagement of the teeth of the first sector in the teeth of the first part of the gate relative to the guide link along the first part of the gate in the distal direction and following the engagement of the teeth of the moved first sector in the toothing of the second part of the slide along the second part of the gate in the proximal direction, so that a reciprocating motion between the guide slot and gear axis is formed.

In a partial aspect of the foregoing aspect of the invention, the maximum angle which comprises the first sector of the gear is defined as: maximum angular first sector = 180 ° - ((WinfceZ per tooth) * total number of teeth in simultaneous engagement with one Part gate) In a further partial aspect of the preceding aspect of the invention, the relative movement between the first part gate and the gear, while the gear rolls on the first part gate and the teeth of the first sector are in engagement with the teeth of the first part gate, the path of the insertion cannula during insertion of the infusion cannula into the tissue.

In one aspect of the invention, the gear is toothed along the entire circumference, hereinafter referred to as a full gear.

In a partial aspect of the above aspect of the invention, the guide slot comprises a linear pin arrangement, which is arranged fixed relative to the base (in an alternative embodiment, a displacement of the pin arrangement transversely to the insertion direction would be conceivable). The full gear rotates the pin assembly during the insertion process (insertion and retraction), wherein the carriage participates in the movement of the Vollzahnradachse along the pin assembly. The teeth of the full gear are in the insertion of the insertion and infusion cannula in engagement with a first side of the pin assembly and roll it along. At a first end of the pin assembly, the full gear rolls around the first end of the pin assembly toward a second side of the pin assembly (also referred to as the turning or apex of the movement). Subsequently, the teeth of the full gear are engaged with the second side of the pin assembly. Since now the side of the engagement changed, the full-toothed axis moves in the same direction of rotation of the full gear (torque orientation from the drive spring does not change) against the direction of insertion for the purpose of withdrawal of the insertion cannula. The movement of the full-toothed axis is guided in an advantageous embodiment by a guideway associated with the guide slot. The distance which the gear performs in the insertion direction, ie how far the needles are displaced in the insertion direction, depends on the length of the linear pin arrangement and is independent of the dimensioning of the full gear.

In an alternative partial aspect of the above aspect of the invention, the guide slot comprises a toothed slide instead of a pin arrangement. The toothed gate is fixedly attached to the housing wall of the patch infusion pump, for example, at the base and forms an elongated protrusion which projects from the wall into the interior of the patch infusion pump. The circumferential side wall of the elongated elevation is toothed, wherein the full gear can engage in this toothing and can move along along this by rotation. As a result, the gear makes a very similar movement as in the previous sub-aspect (pin arrangement).

In an advantageous variant of the two preceding aspects of the above aspect of the invention, the full gear missing one or a few teeth. When the full gear moves toward the vertex of movement described above during the insertion movement, it may be advantageous for the full-tooth axis (associated with the carriage and the cannulas) to not move at the apex for a moment. To realize this function, one or a few teeth are removed from the full gear, which actually at the apex in engagement with the pin assembly resp. the teeth would come. This has the consequence that the full gear at the apex rotates for a moment, without the Vollzahnradachse moves, and until such time until teeth of the full gear engage again with the pin assembly or the toothing. Thereafter, the full gear moves again and performs the return movement.

Other aspects of the invention are set forth below: In one aspect, the invention includes a cannula insertion mechanism for a patch device comprising a housing comprising a base which may also serve as a base for the patch device and which directly or indirectly on the skin of the person using it, - at least one guideway fixedly attached to the housing and defining at least part of an insertion path, - a carriage slidably mounted in the at least one guideway in and against an insertion direction along the guideway is, - a steel cannula, which is fixedly mounted on the carriage and protrudes approximately parallel to the direction of displacement of the carriage, - a drive spring, in particular a torsion spring whose axis is approximately perpendicular to at least one guideway and fixed to a first end of the drive spring attachable to the carriage, - a gear, we lches fixedly attachable to a second end of the drive spring, wherein the axis of rotation coincides with the axis of the drive spring, wherein the toothing of the gear comprises a first sector of the gear, - a guide link, which extends at a distance from at least one guideway, wherein the distance from the geometric dimensions of the carriage, drive spring and gear results, and which is fixedly connected to the housing or the base, wherein the guide slot comprises at least one part of slat, which runs concurrently to the guide track, wherein the at least one partial slat each have a toothing or pin arrangement which, depending on the rotational orientation of the gear, is engageable with the teeth of the first sector, wherein the gear is caused by the release of energy from the drive spring in a rotational movement and thereby the carriage with the steel cannula by engagement of the teeth of the Gear with the toothing or pin arrangement of the at least one part of the gate in a movement along the at least one guideway is displaceable.

In one aspect, the invention includes a cannula insertion mechanism for a patch device having a cannula made of soft plastic, in particular PTFE, which is designed to be pulled over the steel cannula.

In one aspect, the invention includes a cannula insertion mechanism for a patch device, wherein the drive spring is a torsion spring and has a helical shape.

In one aspect, the invention includes a cannula insertion mechanism for a patch device, wherein the drive spring is a torsion spring having the shape of a coil spring.

In one aspect, the invention includes a cannula insertion mechanism for a patch device, wherein the gear comprises a second sector in which there is no toothing.

In one aspect, the invention includes a cannula insertion mechanism for a patch device, wherein the guide slot comprises two partial toothed lobes, wherein the two partial lobes are in the same plane and the toothings are spaced apart, and wherein the spacing of the two partial lobes is determined by the diameter of the gear without its teeth.

In one aspect, the invention includes a cannula insertion mechanism for a patch device, wherein the gear is rotatably mounted on the carriage so that upon release of energy from the drive spring, the gear is rotated relative to the carriage in rotation.

In one aspect, the invention includes a cannula insertion mechanism for a patch device, wherein upon rotation of the gear teeth of the first sector of the gear in a first phase engage with the teeth of the first part of the gate, whereby on the arrangement of the gear is moved on the carriage of the carriage along the guideway in the insertion direction and wherein the teeth of the first sector of the gear engage in a second phase in engagement with the teeth of the second part of the gate, whereby on the arrangements of the gear on the carriage of the carriage along the guide track is moved against the insertion direction.

In one aspect, the invention includes a needle insertion mechanism for a patch device, wherein the first sector of the gear defines a pitch diameter with its teeth, whereby the arc resulting from the sector angle of the first sector and the pitch diameter results in the insertion route of the cannula insertion.

In one aspect, the invention includes a cannula insertion mechanism for a patch device, wherein the sector angle of the first sector is less than 180 °.

In one aspect, the invention includes a cannula insertion mechanism for a patch device wherein the first and second sub-gates are interconnected via further sub-gates.

In one aspect, the invention includes a cannula insertion mechanism for a patch device, wherein the guide slot comprises a partial gate with a pin assembly, wherein the pins of the pin assembly are approximately perpendicular to the direction of insertion and arranged in a straight line, the distances between the pins are constant.

In one aspect, the invention includes a needle insertion mechanism for a patch device, wherein the sector angle of the first sector is 360 °, the teeth of the gear are arranged along the entire circumference of the gear.

In one aspect, the invention comprises a cannula insertion mechanism for a patch device comprising two parallel linear guideways, the carriage having guide elements which are in engagement with the two guideways and allow displacement of the carriage along the guideways and wherein the Carriage comprises a linearly slidable on the carriage spring bearing, to which the first end of the drive spring is fixedly mounted.

In one aspect, the invention comprises a cannula insertion mechanism for a patch device, wherein the gear is rotatably mounted on the spring bearing and thereby linearly slidably mounted in the carriage, wherein a displacement of the gear relative to the carriage in a direction is possible, which in approximately perpendicular to the axis of rotation of the gear and also perpendicular to the guideway or the guideways.

Figures [0043]

Fig. 1 exploded view of the insertion mechanism of a patch infusion pump 1 according to a first embodiment of the invention ers

Fig. 2 view of the parts of the patch infusion pump shown in Fig. 1 in the assembled state

Fig. 3 view of Fig. 2, but without the lid 8 of the insertion mechanism

Fig. 4 horizontal section through the insertion mechanism of FIG. 2nd

5 shows a partial vertical section through the insertion mechanism from FIG. 2

Fig. 6a and 6b detail view of the insertion mechanism on Fig. 2 before release

Fig. 6c and 6d detailed view of the insertion mechanism on Fig. 2 after release

7a to 7g are horizontal sectional views of the first embodiment of the insertion mechanism of Fig. 2 in different stages of insertion of the infusion cannula 3b

8 is an exploded view of the insertion mechanism of a patch infusion pump 100 according to an alternative embodiment

9 is a view of the parts of the patch infusion pump 100 shown in Fig. 8 in assembled to stand (in the initial state)

10 is a plan view of the arrangement of FIG. 9th

11 is a vertical partial section through the arrangement of Fig. 9th

Fig. 12a and 12b horizontal sections at different heights by the arrangement of Fig. 9, which represent the initial state.

Fig. 13a to 13c perspective view and horizontal sections through the embodiment of Fig. 8 during the insertion movement

Fig. 14a to 14c perspective view and horizontal sections through the embodiment of Fig. 8 after insertion, before the withdrawal of the insertion cannula 103a

15a to 15c perspective view and horizontal sections through the embodiment of Fig. 8 during the withdrawal of the insertion cannula 103a

16a to 16c vertical and horizontal sections through the embodiment of Fig. 8 after the withdrawal of the insertion cannula 103a

Fig. 17 exploded view of the insertion mechanism of a patch infusion pump 200 according to an al ternative embodiment

18 is a view of the parts of the patch infusion pump 200 shown in Fig. 17 in assembled state (in the initial state)

19a is a vertical partial section through the arrangement of FIG. 18

Fig. 19b detail of Fig. 19a

Fig. 20 horizontal section through the arrangement of FIG. 18th

Fig. 21 View of the insertion mechanism of the patch infusion pump 200 immediately after release of the

insertion mechanism

Fig. 22 horizontal section through the arrangement of Fig. 18 immediately after release of the mechanism Insertionsme

Fig. 23 horizontal section through the arrangement of Fig. 18 during the insertion movement

Fig. 24 horizontal section through the arrangement of Fig. 18 after insertion, before the withdrawal of

Insertion cannula 203a

Fig. 25 Horizontal section through the arrangement of Fig. 18 during the withdrawal of the insertion cannula 203a

Fig. 26 horizontal section through the arrangement of Fig. 18 after the withdrawal of the insertion cannula 203 a

Fig. 27 exploded view of the insertion mechanism of a patch infusion pump 300 according to another embodiment

28 is a view of the parts of the patch infusion pump 300 shown in Fig. 27 in assembled state (initial state)

FIG. 29 is a partial vertical section through the arrangement of FIG. 28. FIG

Fig. 30 View of the insertion mechanism of the patch infusion pump 300 immediately after release of the

insertion mechanism

FIG. 31 A vertical partial section through the insertion mechanism in the state of FIG. 30. FIG

Fig. 32 View of the insertion mechanism of the patch infusion pump 300 in the final state after

Insertion of infusion cannula 303b and withdrawal of insertion cannula 303a.

33 is an exploded view of the insertion mechanism of a patch infusion pump 400 according to another embodiment

34 is a view of the parts of the patch infusion pump 400 shown in Fig. 33 in assembled state (initial state)

FIG. 35 A vertical partial section through the arrangement from FIG. 34. FIG

FIG. 36 shows a horizontal section through part of the arrangement from FIG. 34 (representing the initial state). FIG.

Fig. 37 vertical section through the insertion mechanism of the patch infusion pump 400 when released

Fig. 38 horizontal section through a part of the arrangement of Fig. 34 during insertion

Fig. 39 horizontal section through a portion of the arrangement of Fig. 34 after insertion, before the withdrawal of the insertion cannula 403 a

Fig. 40 horizontal section through a portion of the arrangement of Fig. 34 during the withdrawal of the insertion onskanüle 403 a

Fig. 41 Perspective view of the arrangement of Fig. 34 in the final state

Fig. 42 Vertical partial section through an amended on the basis of the embodiment of Fig. 27 Ausfüh insurance form with the patch infusion pump 500, in which the insertion mechanism moves in the vertical direction

FIG. 43 Exploded view of the insertion mechanism of a patch infusion pump 600

44 shows a view of the parts of the patch infusion pump 600 shown in FIG. 43 in the assembled state (initial state)

Description of the Figures The following description of the figures and figures show and describe various possible embodiments and embodiments of the invention. This is not a final list of possible embodiments of the invention, but only examples. The skilled person will be apparent from the description and illustration of further embodiments of the invention, without departing from the idea of the invention. Also, by combinations of parts of described embodiments, further embodiments, obvious to the person skilled in the art, embodiments may arise, without departing from the idea of the invention. Such embodiments not shown here are expressly mitgemeint in this document.

FIGS. 1 to 7g show a first embodiment of a cannula insertion mechanism according to the invention for a patch device, here by way of example for a patch infusion pump 1. FIG. 1 shows an exploded view of the first embodiment. It should be noted that for reasons of clarity, the illustration does not show the entire patch infusion pump, but only the portions thereof that are important to the insertion mechanism. Fig. 2 shows the insertion mechanism of Fig. 1 in the assembled state. Fig. 3 shows the same illustration as

Fig. 2, wherein the lid 8 has been removed in Fig. 3. Fig. 4 shows a horizontal section through the insertion mechanism near the base 2a. FIGS. 5 to 6d show further details of the first embodiment. FIGS. 7a to 7g then represent different states in the process of insertion of the infusion cannula 3b.

The patch infusion pump 1 comprises a housing 2, of which in the figures of the first embodiment in each case the base 2a is shown. The base 2a is adhered, for example, by means of a plaster (not shown) directly to the skin of the person using, the patch being placed between the skin and the base 2a. In the region of the base, in which the infusion cannula is inserted through the skin into the tissue, the patch has an opening through which the infusion cannula can be passed.

The insertion mechanism of the first embodiment comprises a cannula ensemble 3 comprising a cannula support 9 with a cannula support base 9a. At the cannula carrier base 9a, the infusion cannula 3b is firmly anchored. Furthermore, the cannula ensemble 3 comprises the insertion cannula support 3c. In the insertion cannula carrier 3, the insertion cannula 3a and the lead 3e are firmly anchored. In this case there is a fluid connection between supply line 3e and insertion cannula 3a. In practice, the substance to be administered, for example the liquid medicament, can be supplied from the reservoir (optionally via a pumping element) via the supply line of the insertion cannula. In the initial state, the insertion cannula 3a protrudes through the lumen of the infusion cannula 3b, with the distal tip of the insertion cannula 3a protruding from the distal end of the infusion cannula 3b. When the infusion cannula 3b is inserted into the tissue of the person using it, the insertion cannula 3a is withdrawn (out of the tissue) through the infusion cannula 3b, the insertion cannula 3a still protruding into the infusion cannula 3b after completion of the retraction, thus preventing fluid communication Feed line 3e and infusion cannula 3b produces, so that the substance to be administered to the user can be supplied. The infusion cannula 3b is movably mounted together with the cannula carrier 9 on the insertion cannula 3a, wherein in the initial state cannula carrier 9 and insertion cannula carrier 3c are connected to one another indirectly via the snap arms 9b.

Embedded in the base 2a is the guideway 2h, which guides by their course, the insertion movement of the cannula ensemble 3. Furthermore, the base 2a also comprises the cannula guide 2f, whose function is to introduce the infusion cannula 3b and the insertion cannula 3a through the base 2a at a predetermined angle into the tissue.

The insertion mechanism of the first embodiment further includes a guide slot 2b fixedly disposed on the base 2a. The guide slot 2b comprises in this embodiment, two partial scenes 2c and 2d, wherein in both a respective toothing 10a resp. 10b. The guide slot 2b is closed except for the opening 2g at the distal end. Inserted into the gate is the gear 4, as well visible in Fig. 4, for example. In the sectional view of Fig. 4, it can be seen that the gear can be divided into two sectors 4a and 4c, wherein the first sector 4a has teeth 4b and the second sector 4c carries no teeth. Teeth 4b can first engage one after another in the toothing 10a and subsequently in the toothing 10b. Perpendicular to the actual gear level of the gear 4 is the gear axis 4d, which is designed as a sleeve.

The insertion mechanism of the first embodiment further comprises a carriage 6, which has an approximately cylindrical shape, see Fig. 1. Fig. 5 shows the carriage 6 in a sectional view. Carriage 6 comprises a carriage axis 6b which extends through the gear axis 4d into the guide track 2h. The gear 4 is rotatably mounted on the carriage axis 6b. Between the carriage 6 and the gear 4, the drive spring 5 is arranged, wherein one end of the spring 5 is fixedly connected to the gear 4 and the second end of the spring 5 is connected to the carriage. When drive spring 5 is a torsion spring.

Insertion cannula carrier 3c and slide 6 are firmly connected to each other via the cannula bridge 6c. The snap arms 9b of the cannula holder 9 are snapped in the initial state with the cannula bridge 6c. The cannula bridge 6c comprises a guide pin 6h (not visible), which, like the carriage axis 6b, engages in the guide track 2h, so that the carriage 6 is mounted so as to be secured against rotation with respect to the guide track 2h and thus relative to the base 2a. In the initial state, a rotation of the gear 4 relative to the carriage 6 (ie also the base 2a) is prevented, however, via the engagement of the catch of the release arm 6a in the blocking cam 4e ( see Fig. 6b). In order to prevent deflection of the release arm 6a to the outside, the insertion mechanism of the first embodiment also comprises a cup-shaped releaser 7. The releaser 7 is mounted on the carriage against rotation by the engagement of securing cam 6d of the carriage 6 in the anti-rotation opening 7c of the releaser 7. As shown in Fig. 6a, the releaser 7 comprises a release window 7a. The releaser is mounted on the carriage 6 via the spring elements 7b and can be pressed in the direction of the base 2a for the purpose of triggering the insertion process. In this case, the release window 7a shifts in the direction of the base (see Fig. 6c and 6d). Now comes the release arm 6a at the level of the release window 7a to lie and thus can deflect outwards, so that blocking cam 4 and release arm 6a disengage. As a result, the applied torque can be released from the drive spring 5.

In the first embodiment shown, the drive spring 5 is tensioned in a clockwise direction, so that acts on the gear 4 when released a torque in the counterclockwise direction. Thus, when released, the gear 4 begins to rotate counterclockwise (FIG. 7a). By the engagement of the teeth 4b in the toothing 10a of the first part of the gate 2c, the gear 4 and thus also the carriage 6 moves along the guide track in the distal direction. Thus, in the sequence, the cannula ensemble is moved in this direction. Movement in the distal direction continues (Figure 7b) until the teeth 4b disengage from the toothing 10a (Figure 7c). At the same time, the cannula holder 9 reaches the cannula guide 2f. Cannula guide 2f comprises a funnel-like tapered guide 2i, which then deflects the holding arms 9c of the cannula holder 9 inwards, whereby they are brought into engagement with the cannula holder 2j. By the deflection of the support arms 9c inwards, the snap arms 9b are in turn deflected outwards, whereby the engagement of the snap arms 9b in the cannula bridge 6c is released. Since there is still a torque applied to the gear 4, this continues to rotate in the counterclockwise direction (Figure 7d). It shifts for a moment no longer along the guideway 2h, but rotates in place until the teeth 4b get into engagement with the teeth 10b of the second part of the gate 2d. Although the gear 4 continues to rotate in the same direction, the gear 4 now begins to slide in the proximal direction along the guideway (Fig. 7e), with the gear also the carriage 6 is moved back. Since the connection between cannula support 9 and cannula bridge 6c is released, only the insertion cannula support 3c is displaced back with the cannula bridge, but not the cannula support 9. As a result, the insertion cannula 3a is withdrawn through the infusion cannula 3b and the infusion cannula remains firmly attached to the cannula holder 2j. Just before the teeth 4b disengage from the teeth 10b (Figure 7f), the release arm 6a blocks further rotation of the gear 4 by engaging the stop flank 4f, thereby stopping the movement Alternatively, other variants are possible for end stops of the movement In particular, the guide slot could be designed in such a way that the gearwheel could come out of engagement with the second part linkage at the end of the return movement without a renewed engagement in the toothing of the first part linkage being possible, if the energy were still stored in the drive spring 5 , the gear would continue to rotate in place without the carriage 6 would move on, so that the retraction movement would also be completed.

As mentioned, the releaser 7 is spring-mounted and secured against rotation on the carriage 6. Triggering / releasing the insertion device thus takes place against the resistance of the spring elements 7b. The lid 8, which covers the region of the guide slot 2b on the base 2a, has a trigger opening 8a, through which the releaser 7 can be actuated in the initial state of the insertion mechanism.

In one embodiment of the first embodiment, the cannula ensemble 3 comprises a guide tube 3d, the task of which is to mechanically stabilize the cannula ensemble 3 during the movement in the distal direction (see FIG. 3). The guide tube 3d encloses the infusion cannula 3b and is fixedly arranged on the cannula carrier base 9a. In this case, the guide tube 3d has a longitudinal slot on its side facing the base 2a. If the cannula ensemble 3 is displaced in the distal direction, the guide tube 3d is opened along the slot in the region of the cannula guide 2f and removed from the rest of the cannula ensemble 3, ie. the infusion cannula 3b and the insertion cannula 3a separated and not passed through the base 2a in the direction of tissue.

The first embodiment shown (as well as analogously to the following) of the insertion mechanism allows in an elegant and simple manner a reciprocating motion with a rotational direction of the gear, which makes it possible to use only one spring for the insertion mechanism. The insertion path, as the way that the insertion cannula 3a performs in the distal direction, depends on the one hand on the size (ie the angle) of the first sector 4a of the gear 4, on the other hand also on the diameter (pitch circle diameter) of the gear 4, which also the distance determined by the first part gate 2c and second part gate 2d. The dimensioning of the first sector has already been discussed above.

From the first embodiment shown, there are simply modifications. For example, the guideway 2h can run straight (as a result, the partial scenery would also be straight).

Another embodiment of the insertion mechanism according to the invention is shown in FIGS. 8 to 16c. The identifiers in this embodiment were named analogously to the embodiment of Fig. 1, the numbering was made such that e.g. the base 2a of the embodiment of Fig. 1 is analogous to the portion 102a of the embodiment of Fig. 8. Since the function of the embodiment of FIG. 8 is analogous or identical to that of FIG. 1, particular emphasis will be given below to the differences between the two embodiments.

8 shows an exploded view of this alternative embodiment with the patch infusion pump 100, wherein it should also be noted in this embodiment that the illustrations of FIGS. 8 to 16c do not show the entire patch infusion pump 100 for reasons of clarity, but only the parts thereof which are of importance for the insertion mechanism. Fig. 9 shows a perspective view of the insertion mechanism of Fig. 8 in the assembled state. FIG. 10 shows a plan view of the arrangement from FIG. 9. FIG.

As in the first embodiment of FIG. 1, in the embodiment of FIG. 8, the ensemble of carriages 106 with the cannula ensemble 103 first performs a displacement in the distal direction upon insertion, with the infusion cannula 103b using the insertion cannula 103a is inserted into the tissue of the person using and following the carriage 106 with the insertion cannula 103a is moved back together in the proximal direction, the cannula support 109 is held together with the infusion cannula 103b on the cannula holder 102j. The required drive energy for the insertion movement is provided by the prestressed drive spring 105, drive spring 105 is a torsion spring, in the example shown a helical torsion spring, whereby a helical torsion spring could be used. The actual drive of the insertion mechanism via the gear 104. In the initial state, the drive spring 105 is biased.

The carriage 106 is secured against rotation but slidably mounted in and against the insertion direction in the guideways 102h and 102h 'of the base 102a. Fixed to the base 102a is the guide slot 102b, which includes a pin assembly 102c with pins 110 and the gear guide 102k, with the pin assembly 102c oriented according to the direction of insertion - as seen, for example, in FIG. The teeth 104b of the gear can be engaged with the pin assembly 102c (see Figs. 12b, 13c, 14b and 15c). Between carriage 106 and gear 104, the spring housing 111 is arranged. The spring housing 111 is secured against rotation by way of the guide spring 111b and the spring housing guide 106e, but is mounted displaceably in the carriage 106 transversely to the insertion direction. Between spring housing 111 and gear 104, the drive spring 105 is arranged, one end of the drive spring 105 is fixedly mounted on the spring housing 111 and the other end of the drive spring 105 is fixedly mounted on the gear 104, the spring housing 111 further comprises a fixedly arranged on the spring housing 111 spring housing axis 111c, on which the gear 104 is rotatably mounted. The spring housing axis 111c extends through the gear 104 into the gear guide 102k (see FIG. 11). The gear guide 102k thus performs, together with the carriage 106, the movement of the spring housing relative to the base 102a. Upon release of the stored energy from the drive spring 105, the gear 104 rotates clockwise relative to the carriage 106 (see FIGS. 12b, 13c, 14b and 15c). By engagement of the teeth 104b of the gear 104 with the pins of the pin assembly 102c, the ensemble of gear 104, spring 105, spring housing 111 and cannula assembly 103 and slide 106 are displaced along the pin assembly 102c in the insertion direction. At the apex of the movement, the cannula holder 109 is fixed to the cannula holder 102j analogously to the first embodiment from FIG. 1 (FIG. 14b). Around the vertex of the insertion movement, gear 104 changes (during continuous clockwise rotation) from one side of pin assembly 102c to the other. This is possible because the spring housing 111 is mounted displaceably in the carriage 106 transversely to the insertion direction. After the change of sides, the gear 104 continues to rotate in the clockwise direction, with the result that the carriage 106 is displaced counter to the direction of insertion, ie the insertion cannula 103a is pulled out of the tissue in the proximal direction through the infusion cannula 103b.

The carriage 106 includes a release arm 106a, which is shown for example in FIG. 8. At its free end tooth 106f is arranged. Base 102a also includes a releaser 107 having a snap arm 107b which is fixedly attached to the base 102a via the releaser base 107a. The snap-action arm 107b can be deflected via the pushbutton 107c. In the initial state of the insertion mechanism, as shown in Figs. 9 and 10, carriage 106 is held in its proximal position by engagement of tooth 106f and snap arm 107b. This connection also holds the spring force of the drive spring 105 by blocking the displacement in the direction of insertion and prevents rotation of the gear 104. Actuation of the button 107c enables the connection between the tooth 106f and the snap arm 107b to be released, thus saving energy stored in the drive spring 105 can be converted into a rotation of the gear 104. At the end of the withdrawal movement of the insertion cannula 103a, the displacement of the carriage 106 in the proximal direction re-engages the tooth 106f and the snap-action arm 107b, thereby blocking further rotation of the toothed wheel 104. Without this re-engagement of tooth 106f and snap-on arm 107b, it would be conceivable in that the gear 104 would continue to rotate if enough energy were stored in the drive spring 105 and the carriage 106 would subsequently be reciprocated until the drive spring 105 was fully relaxed.

The different phases of the insertion process in the embodiment of Figure 8 are shown in various views of FIGS. 12a to 16c.

Also in the embodiment, a guide tube 103d (analogous to guide tube 3d) serve the mechanical stabilization of the cannula ensemble. Functions and parts are the same as in the first embodiment.

An obvious difference between the embodiment of Fig. 1 and Fig. 8 results in the gear. While the gear 4 is divided into a first sector 4a (with teeth 4b) and a second sector 4c (without teeth), gear 104 of the embodiment of FIG. 8 comprises only one sector 104a, which however extends over 360 °, that is whole gear. This simplification has to do with the fact that the two partial scenes 2c and 2d from the first embodiment in the embodiment from FIG. 8 have been brought together to form the pin assembly 102c and are now arranged centrally in the guide slot 102b. As a result, the gear 104 can be passed around the pin assembly 102c, allowing a continuous tooth arrangement on the gear 104.

Compared with the embodiment of FIG. 1, in the embodiment of FIG. 8 there is at least the advantage that the insertion path, that is to say the path by which the infusion cannula 103b is displaced in the direction of tissue during insertion, can be adjusted relatively easily. Namely, by adjusting the length over which the pin assembly 102c extends, the insertion path can be adjusted without changing the dimensioning of the gear or slide. In an extension of the insertion path thus in the embodiment of Fig. 8, the gear must not be increased, which in the embodiment of Fig. 1 by from may be necessary if the maximum angle for the first sector is exceeded at a constant gear size (see general Description). The embodiment of FIG. 8 can thereby be kept narrow even with longer insertion paths.

Another embodiment of the insertion mechanism according to the invention is shown in FIGS. 17 to 26. The identifiers in this embodiment were named analogously to the embodiment of Fig. 1, the numbering was made such that e.g. the base 2a of the embodiment of FIG. 1 is analogous to the part 202a of the embodiment of FIG. 17. Since the function of the embodiment of FIG. 17 is analogous or identical to that of FIG. 1, particular emphasis will be given below to the differences between the two embodiments.

17 shows an exploded view of this further embodiment of the insertion mechanism according to the invention for a patch infusion pump 200, wherein it should also be noted in this embodiment that the illustrations of FIGS. 17 to 26 do not cover the entire patch infusion pump for reasons of clarity 200, but only the parts thereof which are important to the insertion mechanism. Fig. 18 shows the insertion mechanism of the patch infusion pump 200 in the assembled state prior to the initiation of the insertion mechanism (also referred to as the initial state). FIG. 19 a shows a vertical section (drive spring 205 is not cut in this case) through the arrangement of FIG. 18.

Fig. 19b shows a detail of Fig. 19a, in which the separation of the optional guide tube 203d of infusion cannula 203b and insertion cannula 203a is shown. 19b also shows the guidance of the infusion cannula 203b and the insertion cannula 203a through the base 202a along the cannula guide 202f in the direction of the tissue of the user (at this point reference is made to the description of the previous embodiments, which operate the same with respect to the cannula guide shown in Fig. 19b).

Fig. 20 shows a horizontal section through the arrangement of Fig. 18 in the initial state, this presentation in connection with the release of the insertion mechanism will be discussed in detail below.

Fig. 21 shows a view of the insertion mechanism of the patch infusion pump 200 immediately after release of the insertion mechanism. Fig. 22 shows the insertion mechanism immediately after release as a horizontal section, while in the horizontal section of Fig. 23 has started the movement of the carriage 206 in the insertion direction. In the horizontal section of FIG. 24, the infusion cannula 203b is completely inserted into the tissue and the withdrawal of the insertion cannula 203a arrives. FIG. 25 also shows the insertion mechanism of FIG. 17 during the withdrawal movement of the insertion cannula 203a in horizontal section, while FIG Final state of the insertion mechanism is also shown again in horizontal section.

In addition to the fact that the guideways 202h are not bent with respect to the guideway 2h, the main difference between the embodiment of Fig. 17 and that of Fig. 1 is in the reversed motion of the gear and guide slot. In the embodiment of Fig. 1, during the insertion movement, the gear 4 moves together with the carriage 6 along the guide track 2h relative to the base 2a. The carriage 6 is guided over the guide elements 6b in the guideways 2h. The guide slot 2b is fixedly arranged on the base 2a. In the embodiment of Fig. 17, the guide slot 202b is disposed on the carriage 206 which moves along the track 202h during the insertion process. The gear 204 is rotatably mounted on the spring holder 202k, which in turn is fixedly and immovably arranged on the base 202a.

Another difference between the embodiments of Figs. 1 and 17 results in the release (alternatively called release) of the insertion mechanism, which was solved in the embodiment of Fig. 17 in an elegant manner. The operation of the release will now be explained with reference to FIGS. 17, 18, 20 and 22 in particular.

As already mentioned, the gear 204 is rotatably mounted rotatably on the spring holder 202k. Between the gear 204 and the spring holder 202k, the drive spring 205 is arranged, which is designed as a helical torsion spring. It should be mentioned again at this point that the drive spring could also have other shapes, in particular, for example, the spring with the spring holder integrated could be designed as a torsion bar, which would be firmly connected at one end to the gear 204. Back to the shown version; one end of the drive spring 205 is fixedly connected to the spring holder 202k, the other fixed to the gear 204. Energy stored in the spring 205 can then be converted into a rotation of the gear 204 relative to the base 202a. As in the embodiment of Fig. 1, the gear 204 is divided into a first sector 204a with teeth 204b and a second sector 204c without teeth, for the kinematics between gear 204 and guide slot 202b reference is made to the description of the embodiment of Fig. 1, since the kinematics work analogously (taking into account the differences described above). The guide slot 202b is, as mentioned, fixedly arranged on the carriage 206 and, like the embodiment of FIG. 1, has a first part gate 202c and a second part gate 202d.

In the initial state, the spring 205 is biased, so that a moment acts on the gear 204, which is transmitted via the teeth 204b to the first part of the slide 202c on the carriage 206. As a result, the carriage 206 pushes in the distal direction. In the initial state, however, this movement is blocked. For this purpose, release arms 202I are arranged at the base, which have a free end with tooth 202m. One tooth 202m in the initial state engages a tooth 206f of the carriage 206 (the embodiment of FIG. 17 has such a tooth 206f on both sides of the carriage 206). In order to prevent flexing of the free end 202m of the release arm 202I outwardly in the initial state, the insertion mechanism of the patch infusion pump 200 further includes a release peg 207.

The release bracket 207 is connected via the guide arms 207b, which are slidably mounted in the guides 202o, connected to the base 202a. The release clamp further comprises the spring elements 207a, the free ends 207d of which protrude against the bulges 202n of the release arms 2021 and thus resiliently urge the release clamp in the distal direction. The bay 207c of the release bracket 207 supports the gear axis 204d and pushes this also in the distal direction (see, for example, Fig. 18).

As mentioned, Fig. 20 shows a horizontal section through the insertion mechanism in the initial state. Here, it becomes clear how the blocking zones 207e of the release bracket 207 prevent the free ends of the release arms 202m from deflecting. The insertion mechanism can now be released by displacing the release clamp in the proximal direction against the spring force induced by the spring elements 207a. The displacement of the release clamp 207 in the proximal direction also causes the blocking zones 207e to shift in the proximal direction.

In Figs. 21 and 22, the insertion mechanism is shown when the release tab 207 is actuated. In this condition, the free ends 202m of the release arms 202I can now flex outward, allowing movement of the carriage 206 distally along the guideways 202h. The force acting on the gear 204 torque from the spring 205 now causes the gear begins to rotate, in the embodiment of Fig. 17 in the counterclockwise direction. Accordingly, the carriage 206 shifts in the distal direction, whereby the cannula ensemble 203 is also displaced in the insertion direction, which leads analogously to the embodiments described above for insertion of insertion cannula 203a and infusion cannula 203b into the tissue of the user. Fig. 23 shows the insertion mechanism during the movement in the insertion direction.

In Fig. 24, the insertion mechanism is shown upon successful insertion of the cannulas 203a and 203b, but prior to the withdrawal of the insertion cannula 203a. As in the embodiment of Fig. 1, gear 204 rotates between the insertion and withdrawal of the insertion cannula 203a through an angle at which the teeth 204b are neither in engagement with the first sub-gate 202c nor the second sub-gate 202d. Here the carriage stops. Fig. 24 shows the moment in which the teeth 204b are getting into engagement with the second sub-gate 202d. It should be noted that due to the dimensioning of the first sector 204a and the circle diameter of the gear 204, the most proximal tooth of the second sub-gate, half-tooth 206g, is cut so that the movement of the gear 204 is not blocked by undesired interference with the second sub-gate 202d. It should further be noted that in the state of Fig. 24, the cannula support 209 is fixedly connected to the cannula holder 202j (analogous to the previous embodiments) and thus the infusion cannula 203b remains in place upon withdrawal of the insertion cannula 203a.

In Fig. 25, the return movement of the carriage is already in progress, that is, the carriage moves against the insertion direction. As in the embodiment of Fig. 1, the carriage 206 has changed the direction of travel with the gear 204 always rotating therein.

The end of the retraction is shown in FIG. In this state, the arc of the distal end of the guide slot 202b prevents further movement of the carriage 206 in the proximal direction, in which the sheet comes into abutment with the gear 204. Due to the fact that a part of the teeth 204b is further in engagement with the toothing of the second part of the slide 202d, also a further rotation of the gear 204 is no longer possible. The insertion mechanism has subsequently reached its final state.

Another embodiment of the insertion mechanism according to the invention is shown in FIGS. 27 to 32. The identifiers in this embodiment were named analogously to the embodiment of Fig. 1, the numbering was made such that e.g. the base 2a of the embodiment of FIG. 1 is analogous to the part 302a of the embodiment of FIG. 27. Since the function of the embodiment of FIG. 27 is analogous or identical to that of FIG. 1, the differences between the two embodiments will be discussed below.

27 shows an exploded view of this further embodiment according to the invention of the insertion mechanism for a patch infusion pump 300, wherein it should also be noted in this embodiment that the illustrations of FIGS. 27 to 32 do not cover the entire patch infusion pump for reasons of clarity 300, but only the parts thereof that are important to the insertion mechanism.

Also in the embodiment of Fig. 27, the guideways 302h are straight. With the exception of the release and the end blocking, the embodiment of FIG. 27 functions the same as the embodiment of FIG. 1. Otherwise, reference is made to the description of the embodiment of FIG.

The base 302a of the patch infusion pump 300 includes u. a. the guideways 302h, in which the carriage 306 is slidably guided (but secured against rotation) via its guide elements 306b. As in the embodiment of FIG. 1, the drive spring 305 is disposed between the carriage 306 and the gear 304. In the initial state, the torsion spring designed as a drive spring 305 is biased so far that the stored energy reaches at least for a complete insertion. The gear 304 is rotatably mounted in the carriage 306. The base 302a further includes the guide slot 302b, which includes the first sub-gate 302c and the second sub-gate 302d. During the insertion process, the gear 304 rolls (counterclockwise) with its teeth 304b of the first sector 304a first on the first part slide 302c in the insertion direction (ie distal direction), then rotates out of engagement with the first part slide 302c, continues rotating without intervention in the Partial scenes until the teeth 304b reach and engage the second part of the slide 302d, so that upon further rotation of the gear 304, the carriage is moved in the proximal direction to have withdrawn the insertion tube to completion of the insertion process.

As mentioned, one of the differences between the embodiments of FIGS. 1 and 27 is the release of the insertion mechanism (ie the triggering). Referring to Figs. 27 to 31, the following will be given to the initiation of the insertion process. Movably arranged on the carriage 306 is the releaser 307, which is arranged in the release bearing 306a on its axis of rotation 307c.

The releaser 307 can be easily rotated about its horizontal axis of rotation 307c. At the distal end of the releaser 307, the blocking element 307b is fixed, which is best seen in FIG. In the initial state, as shown in Fig. 28, the blocking member 307b is engaged with the blocking recess 304e. As can be clearly seen in Fig. 27, the blocking recess 304e is channel-shaped and terminates in the stop flank 304g. Due to the counterclockwise torque acting on the gear from the spring, in the initial state, the blocking element 307b and the stop flank 304g engage and block rotation of the gear 304 relative to the carriage 306.

The releaser 307 includes at its proximal end the edge 307a, which in the initial state presses against the arm-shaped fuse 306d. The fuse 306d is designed as a flexible arm. If, for releasing the insertion mechanism, the releaser 307 is pressed at its proximal end in the direction of the base 302a, the securing device 306d deviates in the proximal direction, whereby the edge 307a is moved in the direction of the base 302a and consequently the engagement between the blocking element 307b and the stop flank 304g is released because the releaser 307 is rotated about its axis of rotation 307c. Thus, rotation of the gear 304 relative to the carriage 306 is now possible and the insertion process starts.

At the end of the insertion process, see Fig. 32, the teeth 304b are still engaged with the second sub-gate 302d, which means that the still-acting torque could result in further displacement of the carriage 306 in the proximal direction, however, this is prevented by the proximal termination 3021 of the guideways 302h, in which the termination 3021 blocks further movement of the guide members 306b. The insertion process is thus finished and the mechanism stops.

Another embodiment of the insertion mechanism according to the invention is shown in FIGS. 33 to 41. The identifiers in this embodiment were named analogously to the embodiment of Fig. 8, the numbering was made such that e.g. the base 102a of the embodiment of Fig. 8 is analogous to the portion 402a of the embodiment of Fig. 33. Since the function of the embodiment of FIG. 33 is analogous or identical to that of FIG. 8, the differences between the two embodiments will be discussed below. It is also expressly made to the description of the embodiment of FIG. 8 at this point.

33 shows an exploded illustration of this alternative embodiment with the patch infusion pump 400, wherein it should also be noted in this embodiment that the illustrations of FIGS. 33 to 41 do not show the entire patch infusion pump 100 for reasons of clarity, but only the parts thereof which are of importance for the insertion mechanism. Fig. 34 shows a perspective view of the insertion mechanism of Fig. 33 in the assembled state.

Fig. 35 shows a perspective and partial vertical section through the insertion mechanism of the patch infusion pump 400, wherein the drive spring 405 as well as the gear 404 were not cut. The insertion mechanism is shown in Fig. 35 in its initial state with preloaded drive spring 405. FIG. 36 shows a horizontal section through the insertion mechanism in the same state as in FIG. 35. FIG.

Fig. 37 shows a vertical section through the insertion mechanism at the moment of release of the mechanism in which the engagement between the release arm 406a with tooth 406f and the releaser 407 is released. It should be added that only the teeth are shown by the releaser 407, which, respectively, the carriage in its proximal starting position, respectively. Hold end position. Those skilled in the art will appreciate possible overall implementations of the releaser 407 from the various variants shown in this specification and its general knowledge, without departing from the spirit of the present invention.

The various phases of the insertion process are shown in FIGS. 36, 38, 39 and 40 in the form of horizontal sections through the insertion mechanism. FIG. 38 shows the insertion mechanism of the patch infusion pump 400 during the insertion movement in the distal direction. FIG. 39 shows the embodiment of FIG. 33 at the moment when the gear 404 together with the carriage 406 and the cannula ensemble 403 at the vertex of movement. Fig. 40 shows the insertion mechanism during the withdrawal of the insertion cannula 403a. Fig. 41 is a perspective view of the insertion mechanism of the patch infusion pump 400 in the final state after insertion, it being noteworthy that the teeth 406f and releaser 407 are again engaged, so that further rotation of the gear 404 is prevented.

There are differences between the embodiments of Fig. 8 and Fig. 33. The main difference lies in the guidance. The guide slot 102b in the embodiment of FIG. 8 includes the pin assembly 102c. In the embodiment of FIG. 33, as an alternative to the pin assembly 102c, the toothed part race 402c has been arranged. Functionally, the pin assembly 102c is a reduced special case of the toothed parting cuscles 402c. Both variants function equivalently.

Another difference between the embodiments of Figs. 8 and 33 is in the release, it being noted that the release of Fig. 33 is not fully shown in the figures.

The linear guideways 102h, 102h 'and 402h, or the guide elements 106b and 406b on the carriages 106 and 406, are also designed differently. These are functionally equivalent alternatives.

Based on the embodiment of Fig. 27, Fig. 42 shows a slightly modified embodiment in a patch infusion pump 500. As shown in Fig. 42, the insertion mechanism is not disposed on the base 502a, but on the wall 502e and Movement of the insertion mechanism is vertical rather than horizontal. Otherwise, the insertion mechanism of the embodiment of FIG. 42 has the same structure as that of FIG. 27 and functions in the same manner, for which reason reference is also made to the description of FIGS. 27 to 32 and again to the references therein. The identifiers in FIG. 42 are selected analogously to the identifiers from FIGS. 27 to 32.

A further embodiment in the form of the patch infusion pump 600, which is based primarily on the embodiment of FIG. 27, is shown in FIGS. 43 and 44. The designators in FIGS. 43 and 43 are selected analogously to the designators from FIGS. 27 to 32. As in the embodiment of FIG. 42, the insertion mechanism of the patch infusion pump 600 is disposed on the wall of the patch infusion pump 600, namely on the wall 602e. In contrast to the embodiment of Fig. 27, the insertion movement of the insertion mechanism is along the circumference of the wall 602e, which is why e.g. the carriage 606 is slightly curved.

Fig. 43 shows an exploded view of the insertion mechanism of the patch infusion pump 600. Fig. 44 shows the insertion mechanism of the patch infusion pump 600 assembled in its initial state.

Designator [0100] 1 patch pump 2 housing 2a base 2b guide slot 2c first part gate 2d second part track 2e wall 2f cannula guide 2g opening 2h guide track 2i guide (funnel-like) 2j cannula holder 3 cannula ensemble 3a insertion cannula 3b infusion cannula 3c insertion cannula carrier 3d guide tube 3e supply line 4 toothed wheel 4a first sector 4b teeth 4c second sector 4d gear axle 4e blocking cam 4f stop flank 5 drive spring 6 slide 6a release arm 6b slide axle 6c cannula bridge 6d safety cam 6h guide pin 7 release 7a release window 7b spring element 7c anti-rotation opening 8 cover 8a release opening 9 cannula support 9a cannula support base 9b snap arms 9c support arms 10a toothing first Partial gate 10b Teeth second part gate 100 Patch pump 102 Housing 102a Base 102b Guide slot 102c Pin arrangement (part gate) 102h Track 102h 'Track 102i Guide 102j Needle holder 102k Gear guide 103 Canoe lenensemble 103a insertion cannula 103b infusion cannula 103c insertion cannula support 103d guide tube 103e supply line 104 gear 104a first sector 104b teeth 105 drive spring 106 slide 106a release arm 106b guide elements 106c cannula bridge 106e spring housing guide 106f tooth 107 release 107a release base 107b snap 107c button 109 cannula support 109a cannula support base 109b snap arms 109c support arms 110 pins 111 spring housing 111a housing 111b guide spring 111c spring housing axis 200 patch infusion pump 202 housing 202a base 202b guide slot 202c first sub-gate 202d second sub-gate 202f cannula guide 202h guideways 202i guide 202] cannula holder 202k spring holder 202I release arms 202m free end with tooth 202n bulge 202o guide 203 cannula ensemble 203a insertion cannula 203b infusion cannula 203c insertion cannula support 203d guide tube 203e supply line 204 gear 204a first sector 204b teeth 204c z continue sector 204d gear axis 205 drive spring 206 slide 206b guide elements 206c cannula bridge 206f tooth 206g half tooth 207 release clamp 207a spring elements 207b guide arms 207c bay 207d free end 207e blocking zone 209 cannula support 209a cannula support base 209b snap arms 209c support arms 300 patch infusion pump 302 housing 302a base 302b guide slot 302c first part gate 302d second sub-gate 302e wall 302h guideway 3021 proximal end of guideway 303 cannula assembly 303a insertion cannula 303b infusion cannula 303c insertion cannula carrier 303d guide tube 303e lead 304 gear 304a first sector 304b teeth 304c second sector 304d gear axis 304e blocking recess 304g stop flank 305 drive spring 306 slide 306a release bearing 306b guide elements 306c cannula bridge 306d securing 307 releaser 307a edge 307b blocking element 307c rotation axis 309 cannula support 309a cannula support base 309b snap arms 309 c Holding arms 400 Patch infusion pump 402 Housing 402a Base 402b Guide track 402c Tooth arrangement 402f Needle guide 402h Guideway 402i Guide 402j Needle holder 402k Gear guide 403 Needle assembly 403a Insertion cannula 403b Infusion cannula 403c Insertion cannula carrier 403d Guide tube 403e Lead 404 Gear 404b Teeth 405 Drive spring 406 Carriage 406a Release arms 406b Guide elements 406e Spring housing guide 406f Tooth 407 Freigeber (Tooth) 409 Cannulet Holder 409a Cannulet Holder Base 409b Retaining Rods 409c Retaining Arms 411 Spring Housing 411a Housing 411b Guide Spring 411c Spring Housing Axle

Claims (21)

500 patch infusion pump 502 housing 502a base 502d second part 502e wall 503 cannula ensemble 504 gear 505 drive spring 506 slide 600 patch infusion pump 602 housing 602a base 602c first part gate 602d second part gate 602e wall 602h track 603 needle assembly 604 gear 605 drive spring 606 carriage claims A reciprocating drive for an insertion mechanism for an administering device comprising - a planar or domed base - a guideway formed in or on the base defining a proximal and a distal end and therebetween a straight line or a curve - one with the A base connected drive track having a plurality of drive sections, wherein a first drive section and a second drive section are opposite and parallel to the straight or to the curve of the guideway, - provided a slide rotationally fixed to the base and along or in the guideway between a proximal Schlittenendposition and a distal Schlittenendposition slidably mounted - a drive wheel at least rotatably mounted in the carriage, - a torque source connected between the carriage and the drive wheel, by which the drive wheel relative to the base and slide in rotation is displaceable, wherein upon rotation of the drive wheel of the Moving carriage starting from particular the proximal Schlittenendposition by a positive or non-positive engagement of the drive wheel in the first drive section along or in the guideway in the distal direction, to the distal end of the first drive portion of the positive or non-positive engagement of the drive wheel from the first to the second Drive section changes by further rotation of the drive wheel and thus moves the carriage along or in the guideway in the proximal direction. 2. A drive according to the preceding claim, wherein the carriage a supply line is arranged with a lumen and guided in or on the carriage through which a substance to be administered, in particular a fluid medicament, can be passed. 3. A drive according to the preceding claim, wherein at the distal end of the carriage, a cannula bridge is arranged, at which the supply line terminates and a proximal end of an insertion cannula is arranged with a lumen, wherein the lumen of the supply line and the lumen of the insertion cannula are interconnected in that the substance to be administered can be conducted from the supply line into the insertion cannula, and wherein the insertion cannula makes a displacement of the carriage in the distal as well as in the proximal direction. 4. A drive according to the preceding claim, wherein the first and the second drive portion each comprise a toothing or a pin arrangement, wherein the drive wheel is a gear and wherein the gear can engage with the toothing or the pin arrangement. 5. A drive according to claim 4, wherein the gear comprises a first sector which is toothed, wherein the first sector may comprise up to 360 °. 6. A drive according to the preceding claim, wherein the torque source can be maintained by a release device in a locked, in particular biased state. 7. A drive according to claim 6, wherein the release device consists of a releasable rotation between the drive wheel and the carriage or between the drive wheel and the base. 8. A drive according to claim 7, wherein the release means consists of a releasable fuse which prevents displacement of the carriage relative to the base. 9. A cannula insertion mechanism for a patch device, comprising - a drive according to one of claims 3 to 8, - an infusion cannula having a distal and a proximal end, through which the insertion cannula is passed, wherein fixedly attached to the proximal end of the infusion cannula a cannula carrier is, wherein on the cannula carrier, a connecting means, in particular one or more Schnapparme, is arranged, via which the cannula carrier is releasably connectable to the cannula bridge, when the insertion cannula is passed through the infusion cannula so far that the cannula carrier rests against the cannula bridge. 10. cannula insertion mechanism according to the preceding claim with a drive according to claim 5 to 8, wherein the first sector of the gear less than 360 °, in particular less than 180 °, and the gear comprises a second sector, which has no toothing. 11. The cannula insertion mechanism according to the preceding claim, wherein the teeth of the first sector of the gear engage in the movement of the carriage in the distal direction in the toothing or pin arrangement of the first drive portion, wherein at the end of the first drive portion, the gear is rotated so far that the teeth except Engage with the toothing or the pin arrangement of the first drive section, wherein the teeth of the first sector with further rotation of the gear immediately or after further rotation by a certain angle engage the toothing or pin arrangement of the second drive section, whereby in the sequence further rotation of the gear of the carriage in the proximal direction shifts. 12. The cannula insertion mechanism according to the preceding claim, wherein at the distal end of the first drive portion, the connecting means of the cannula support is moved by guide elements on the base, so that the connection between the cannula support and cannula bridge is released and the connection means is fixed to the base. 13. cannula insertion mechanism according to claim 9 with a drive according to one of claims 5 to 8, wherein the drive track comprises a pin assembly, which consists of linearly arranged behind one another pins, where a first longitudinal side of the pin assembly serves as a first drive section and a second longitudinal side as the second drive section serves, wherein the carriage comprises a linearly displaceable on the carriage transversely to the guide rail spring bearing, on which the gear is rotatably mounted, wherein at the end of the first drive portion, which is formed by the last pin in the pin assembly, the gear rotates about the last pin, wherein the spring bearing is moved transversely to the carriage, and so is moved together with the gear on the second longitudinal side of the pin assembly, so that the gear with the second drive portion engages. 14. A cannula insertion mechanism according to the preceding claim, wherein the first sector of the gear comprises 360 °. 15. The cannula insertion mechanism according to claim 13, wherein the first sector of the toothed wheel is smaller than 360 ° by an angle .alpha., Wherein the toothed wheel and the first drive section are arranged relative to one another such that at the end of the first drive section the toothed wheel has rotated so far that the teeth of the first Sector out of engagement with the pin assembly and the carriage lingers for a rotation of the gear by the rotation angle α in place, before upon further rotation, the teeth of the first sector again engage with the pin assembly and the carriage together with the gear along the second Drive section moves in the proximal direction. 16. cannula insertion mechanism according to claim 9 with a drive according to claim 3, wherein the drive wheel is configured as a friction wheel, wherein the drive track comprises a plurality of drive portions, which constitute friction surfaces for the friction wheel, wherein the friction wheel rolls upon release of torque from the torque source to the friction surfaces. 17. The cannula insertion mechanism according to any one of claims 9 to 16, wherein the displacement of the carriage in the proximal direction is limited by a stop in the proximal Schlittenendposition, in particular the proximal end of the guide track, whereby the rotation of the drive wheel is stopped. 18. A cannula insertion mechanism according to any one of claims 9 to 17, wherein the torque source is a spring, in particular a torsion spring, which has a helical or spiral shape. 19. A cannula insertion mechanism according to any one of claims 9 to 17, wherein the torque source is a torsion bar. 20. A patch pump comprising a cannula insertion mechanism according to any one of claims 9 to 19. 21. A patch injector comprising a cannula insertion mechanism according to any one of claims 9 to 19.